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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SIX1_SIX3_SIX2

Z-value: 0.33

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Transcription factors associated with SIX1_SIX3_SIX2

Gene Symbol Gene ID Gene Info
SIX1
ENSG00000126778.7 SIX homeobox 1
SIX3
ENSG00000138083.3 SIX homeobox 3
SIX2
ENSG00000170577.7 SIX homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SIX1hg19_v2_chr14_-_61124977_611250370.473.5e-01Click!
SIX2hg19_v2_chr2_-_45236540_452365770.404.3e-01Click!
SIX3hg19_v2_chr2_+_45168875_45168916-0.128.2e-01Click!

Activity profile of SIX1_SIX3_SIX2 motif

Sorted Z-values of SIX1_SIX3_SIX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_171640291 0.23 ENST00000409885.1
ERICH2
glutamate-rich 2
chr14_+_51026844 0.13 ENST00000554886.1
ATL1
atlastin GTPase 1
chr6_+_53794780 0.12 ENST00000505762.1
ENST00000511369.1
ENST00000431554.2
MLIP
RP11-411K7.1
muscular LMNA-interacting protein
RP11-411K7.1
chr3_+_184530173 0.11 ENST00000453056.1
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr1_-_169337176 0.11 ENST00000472647.1
ENST00000367811.3
NME7
NME/NM23 family member 7
chr7_+_99746514 0.11 ENST00000341942.5
ENST00000441173.1
LAMTOR4
late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
chr19_+_42824511 0.10 ENST00000601644.1
TMEM145
transmembrane protein 145
chr16_+_22517166 0.10 ENST00000356156.3
NPIPB5
nuclear pore complex interacting protein family, member B5
chr3_+_42850959 0.09 ENST00000442925.1
ENST00000422265.1
ENST00000497921.1
ENST00000426937.1
ACKR2
KRBOX1
atypical chemokine receptor 2
KRAB box domain containing 1
chr1_+_152730499 0.08 ENST00000368773.1
KPRP
keratinocyte proline-rich protein
chr9_-_113018746 0.08 ENST00000374515.5
TXN
thioredoxin
chr11_-_118134997 0.08 ENST00000278937.2
MPZL2
myelin protein zero-like 2
chr16_-_28550320 0.08 ENST00000395641.2
NUPR1
nuclear protein, transcriptional regulator, 1
chr1_+_40942887 0.08 ENST00000372706.1
ZFP69
ZFP69 zinc finger protein
chr1_-_51791596 0.08 ENST00000532836.1
ENST00000422925.1
TTC39A
tetratricopeptide repeat domain 39A
chr3_+_52448539 0.07 ENST00000461861.1
PHF7
PHD finger protein 7
chr19_-_43702231 0.07 ENST00000597374.1
ENST00000599371.1
PSG4
pregnancy specific beta-1-glycoprotein 4
chr8_-_123139423 0.07 ENST00000523792.1
RP11-398G24.2
RP11-398G24.2
chr20_-_55100981 0.07 ENST00000243913.4
GCNT7
glucosaminyl (N-acetyl) transferase family member 7
chr19_+_50015870 0.07 ENST00000599701.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr3_-_11685345 0.07 ENST00000430365.2
VGLL4
vestigial like 4 (Drosophila)
chr19_+_42055879 0.07 ENST00000407170.2
ENST00000601116.1
ENST00000595395.1
CEACAM21
AC006129.2
carcinoembryonic antigen-related cell adhesion molecule 21
AC006129.2
chr3_+_178865887 0.07 ENST00000477735.1
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr11_-_59633951 0.07 ENST00000257264.3
TCN1
transcobalamin I (vitamin B12 binding protein, R binder family)
chr19_-_42916499 0.07 ENST00000601189.1
ENST00000599211.1
LIPE
lipase, hormone-sensitive
chr10_-_38265517 0.06 ENST00000302609.7
ZNF25
zinc finger protein 25
chr5_-_142077569 0.06 ENST00000407758.1
ENST00000441680.2
ENST00000419524.2
FGF1
fibroblast growth factor 1 (acidic)
chr1_-_207119738 0.06 ENST00000356495.4
PIGR
polymeric immunoglobulin receptor
chr19_+_17579556 0.06 ENST00000442725.1
SLC27A1
solute carrier family 27 (fatty acid transporter), member 1
chr1_+_241695424 0.06 ENST00000366558.3
ENST00000366559.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr2_-_105953912 0.05 ENST00000610036.1
RP11-332H14.2
RP11-332H14.2
chr16_-_28550348 0.05 ENST00000324873.6
NUPR1
nuclear protein, transcriptional regulator, 1
chr8_-_95487272 0.05 ENST00000297592.5
RAD54B
RAD54 homolog B (S. cerevisiae)
chr12_-_7077125 0.05 ENST00000545555.2
PHB2
prohibitin 2
chr9_-_27005686 0.05 ENST00000380055.5
LRRC19
leucine rich repeat containing 19
chrX_+_13587712 0.05 ENST00000361306.1
ENST00000380602.3
EGFL6
EGF-like-domain, multiple 6
chr15_-_100258029 0.05 ENST00000378904.2
DKFZP779J2370
DKFZP779J2370
chr4_+_70894130 0.05 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
HTN3
histatin 3
chr1_-_171711387 0.05 ENST00000236192.7
VAMP4
vesicle-associated membrane protein 4
chr7_+_75511362 0.05 ENST00000428119.1
RHBDD2
rhomboid domain containing 2
chr1_+_160709029 0.05 ENST00000444090.2
ENST00000441662.2
SLAMF7
SLAM family member 7
chr14_+_62462541 0.05 ENST00000430451.2
SYT16
synaptotagmin XVI
chrX_+_1733876 0.04 ENST00000381241.3
ASMT
acetylserotonin O-methyltransferase
chr14_+_24025345 0.04 ENST00000557630.1
THTPA
thiamine triphosphatase
chr1_+_87595433 0.04 ENST00000469312.2
ENST00000490006.2
RP5-1052I5.1
long intergenic non-protein coding RNA 1140
chr11_-_82782952 0.04 ENST00000534141.1
RAB30
RAB30, member RAS oncogene family
chr7_+_138915102 0.04 ENST00000486663.1
UBN2
ubinuclein 2
chr1_+_241695670 0.04 ENST00000366557.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr2_-_114514181 0.04 ENST00000409342.1
SLC35F5
solute carrier family 35, member F5
chr4_-_156298087 0.04 ENST00000311277.4
MAP9
microtubule-associated protein 9
chr4_+_11470867 0.04 ENST00000515343.1
RP11-281P23.1
RP11-281P23.1
chr10_+_18948311 0.04 ENST00000377275.3
ARL5B
ADP-ribosylation factor-like 5B
chr19_-_37407172 0.04 ENST00000391711.3
ZNF829
zinc finger protein 829
chr11_+_17298522 0.04 ENST00000529313.1
NUCB2
nucleobindin 2
chr4_-_156297949 0.04 ENST00000515654.1
MAP9
microtubule-associated protein 9
chr4_+_78829479 0.04 ENST00000504901.1
MRPL1
mitochondrial ribosomal protein L1
chr19_+_11039391 0.04 ENST00000270502.6
C19orf52
chromosome 19 open reading frame 52
chr6_+_53964336 0.04 ENST00000447836.2
ENST00000511678.1
MLIP
muscular LMNA-interacting protein
chr15_-_31521567 0.04 ENST00000560812.1
ENST00000559853.1
ENST00000558109.1
RP11-16E12.2
RP11-16E12.2
chr7_-_92219698 0.04 ENST00000438306.1
ENST00000445716.1
FAM133B
family with sequence similarity 133, member B
chr12_+_2912363 0.04 ENST00000544366.1
FKBP4
FK506 binding protein 4, 59kDa
chr15_+_91416092 0.04 ENST00000559353.1
FURIN
furin (paired basic amino acid cleaving enzyme)
chr16_+_28763108 0.04 ENST00000357796.3
ENST00000550983.1
NPIPB9
nuclear pore complex interacting protein family, member B9
chr1_+_198189921 0.04 ENST00000391974.3
NEK7
NIMA-related kinase 7
chr9_+_67977438 0.04 ENST00000456982.1
RP11-195B21.3
Protein LOC644249
chr7_-_34978980 0.04 ENST00000428054.1
DPY19L1
dpy-19-like 1 (C. elegans)
chr8_+_121457642 0.04 ENST00000305949.1
MTBP
Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa
chr11_-_76155700 0.04 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chr6_+_96969672 0.04 ENST00000369278.4
UFL1
UFM1-specific ligase 1
chr2_-_150444116 0.04 ENST00000428879.1
ENST00000422782.2
MMADHC
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr3_-_125900369 0.04 ENST00000490367.1
ALDH1L1
aldehyde dehydrogenase 1 family, member L1
chr3_-_178976996 0.04 ENST00000485523.1
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr11_+_100862811 0.04 ENST00000303130.2
TMEM133
transmembrane protein 133
chr5_+_71616188 0.04 ENST00000380639.5
ENST00000543322.1
ENST00000503868.1
ENST00000510676.2
ENST00000536805.1
PTCD2
pentatricopeptide repeat domain 2
chr14_+_61449076 0.04 ENST00000526105.1
SLC38A6
solute carrier family 38, member 6
chr1_+_214776516 0.04 ENST00000366955.3
CENPF
centromere protein F, 350/400kDa
chr20_+_36661910 0.04 ENST00000373433.4
RPRD1B
regulation of nuclear pre-mRNA domain containing 1B
chr12_+_7052974 0.04 ENST00000544681.1
ENST00000537087.1
C12orf57
chromosome 12 open reading frame 57
chr16_+_22524379 0.04 ENST00000536620.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr22_+_37257015 0.04 ENST00000447071.1
ENST00000248899.6
ENST00000397147.4
NCF4
neutrophil cytosolic factor 4, 40kDa
chr4_+_129349188 0.04 ENST00000511497.1
RP11-420A23.1
RP11-420A23.1
chr10_-_103603523 0.04 ENST00000370046.1
KCNIP2
Kv channel interacting protein 2
chr2_+_74361599 0.03 ENST00000401851.1
MGC10955
MGC10955
chr18_+_61575200 0.03 ENST00000238508.3
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr11_+_17298543 0.03 ENST00000533926.1
NUCB2
nucleobindin 2
chr16_+_451826 0.03 ENST00000219481.5
ENST00000397710.1
ENST00000424398.2
DECR2
2,4-dienoyl CoA reductase 2, peroxisomal
chr12_+_147052 0.03 ENST00000594563.1
AC026369.1
Uncharacterized protein
chr20_+_62694834 0.03 ENST00000415602.1
TCEA2
transcription elongation factor A (SII), 2
chr19_-_52097613 0.03 ENST00000301439.3
AC018755.1
HCG2008157; Uncharacterized protein; cDNA FLJ30403 fis, clone BRACE2008480
chr3_+_113609472 0.03 ENST00000472026.1
ENST00000462838.1
GRAMD1C
GRAM domain containing 1C
chr4_-_156298028 0.03 ENST00000433024.1
ENST00000379248.2
MAP9
microtubule-associated protein 9
chr2_-_55459294 0.03 ENST00000407122.1
ENST00000406437.2
CLHC1
clathrin heavy chain linker domain containing 1
chr11_+_85339623 0.03 ENST00000358867.6
ENST00000534341.1
ENST00000393375.1
ENST00000531274.1
TMEM126B
transmembrane protein 126B
chr7_-_92219337 0.03 ENST00000456502.1
ENST00000427372.1
FAM133B
family with sequence similarity 133, member B
chr18_-_51750948 0.03 ENST00000583046.1
ENST00000398398.2
MBD2
methyl-CpG binding domain protein 2
chr11_+_27062502 0.03 ENST00000263182.3
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr5_-_159846066 0.03 ENST00000519349.1
ENST00000520664.1
SLU7
SLU7 splicing factor homolog (S. cerevisiae)
chr13_-_60737898 0.03 ENST00000377908.2
ENST00000400319.1
ENST00000400320.1
ENST00000267215.4
DIAPH3
diaphanous-related formin 3
chr10_+_48359344 0.03 ENST00000412534.1
ENST00000444585.1
ZNF488
zinc finger protein 488
chr10_-_33405600 0.03 ENST00000414308.1
RP11-342D11.3
RP11-342D11.3
chr13_-_41837620 0.03 ENST00000379477.1
ENST00000452359.1
ENST00000379480.4
ENST00000430347.2
MTRF1
mitochondrial translational release factor 1
chr10_+_51549498 0.03 ENST00000358559.2
ENST00000298239.6
MSMB
microseminoprotein, beta-
chr1_-_108743471 0.03 ENST00000569674.1
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr3_-_149095652 0.03 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr1_+_16330723 0.03 ENST00000329454.2
C1orf64
chromosome 1 open reading frame 64
chr6_+_31554962 0.03 ENST00000376092.3
ENST00000376086.3
ENST00000303757.8
ENST00000376093.2
ENST00000376102.3
LST1
leukocyte specific transcript 1
chr19_+_11457232 0.03 ENST00000587531.1
CCDC159
coiled-coil domain containing 159
chr19_-_36606181 0.03 ENST00000221859.4
POLR2I
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
chr9_+_97766409 0.03 ENST00000425634.2
C9orf3
chromosome 9 open reading frame 3
chr12_-_118796910 0.03 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr11_+_114168085 0.03 ENST00000541754.1
NNMT
nicotinamide N-methyltransferase
chr11_-_112034831 0.03 ENST00000280357.7
IL18
interleukin 18 (interferon-gamma-inducing factor)
chr9_+_12693336 0.03 ENST00000381137.2
ENST00000388918.5
TYRP1
tyrosinase-related protein 1
chr2_+_161993465 0.03 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr10_+_5238793 0.03 ENST00000263126.1
AKR1C4
aldo-keto reductase family 1, member C4
chr16_-_47493041 0.03 ENST00000565940.2
ITFG1
integrin alpha FG-GAP repeat containing 1
chr20_+_44074071 0.03 ENST00000595203.1
AL031663.2
CDNA FLJ26875 fis, clone PRS08969; Uncharacterized protein
chr11_-_35547151 0.03 ENST00000378878.3
ENST00000529303.1
ENST00000278360.3
PAMR1
peptidase domain containing associated with muscle regeneration 1
chr12_+_7053172 0.03 ENST00000229281.5
C12orf57
chromosome 12 open reading frame 57
chr3_-_178984759 0.03 ENST00000349697.2
ENST00000497599.1
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr3_-_46786245 0.03 ENST00000442359.2
PRSS45
protease, serine, 45
chr12_+_49717081 0.03 ENST00000547807.1
ENST00000551567.1
TROAP
trophinin associated protein
chr2_-_207629997 0.03 ENST00000454776.2
MDH1B
malate dehydrogenase 1B, NAD (soluble)
chr22_-_44258360 0.03 ENST00000330884.4
ENST00000249130.5
SULT4A1
sulfotransferase family 4A, member 1
chr3_+_141144963 0.03 ENST00000510726.1
ZBTB38
zinc finger and BTB domain containing 38
chr2_+_120517174 0.03 ENST00000263708.2
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr9_+_97766469 0.03 ENST00000433691.2
C9orf3
chromosome 9 open reading frame 3
chr4_-_14889791 0.03 ENST00000509654.1
ENST00000515031.1
ENST00000505089.2
LINC00504
long intergenic non-protein coding RNA 504
chr7_+_12727250 0.03 ENST00000404894.1
ARL4A
ADP-ribosylation factor-like 4A
chr17_+_43213004 0.02 ENST00000586346.1
ENST00000398322.3
ENST00000592162.1
ENST00000376955.4
ENST00000321854.8
ACBD4
acyl-CoA binding domain containing 4
chr6_-_138428613 0.02 ENST00000421351.3
PERP
PERP, TP53 apoptosis effector
chr1_+_160709076 0.02 ENST00000359331.4
ENST00000495334.1
SLAMF7
SLAM family member 7
chr4_-_153332886 0.02 ENST00000603841.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr5_-_141392538 0.02 ENST00000503794.1
ENST00000510194.1
ENST00000504424.1
ENST00000513454.1
ENST00000458112.2
ENST00000542860.1
ENST00000503229.1
ENST00000500692.2
ENST00000311337.6
ENST00000504139.1
ENST00000505689.1
GNPDA1
glucosamine-6-phosphate deaminase 1
chr16_+_27214802 0.02 ENST00000380948.2
ENST00000286096.4
KDM8
lysine (K)-specific demethylase 8
chr3_-_10028366 0.02 ENST00000429759.1
EMC3
ER membrane protein complex subunit 3
chr21_+_37442239 0.02 ENST00000530908.1
ENST00000290349.6
ENST00000439427.2
ENST00000399191.3
CBR1
carbonyl reductase 1
chr1_+_53793885 0.02 ENST00000445039.2
RP4-784A16.5
RP4-784A16.5
chr8_-_48651648 0.02 ENST00000408965.3
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr2_-_152146385 0.02 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr22_-_43091639 0.02 ENST00000249005.2
ENST00000381278.3
A4GALT
alpha 1,4-galactosyltransferase
chr12_-_112614506 0.02 ENST00000548588.2
HECTD4
HECT domain containing E3 ubiquitin protein ligase 4
chr2_-_180871780 0.02 ENST00000410053.3
ENST00000295749.6
ENST00000404136.2
CWC22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr4_-_52883786 0.02 ENST00000343457.3
LRRC66
leucine rich repeat containing 66
chr15_+_62853562 0.02 ENST00000561311.1
TLN2
talin 2
chr14_+_73563735 0.02 ENST00000532192.1
RBM25
RNA binding motif protein 25
chr5_-_143550241 0.02 ENST00000522203.1
YIPF5
Yip1 domain family, member 5
chr14_-_94759595 0.02 ENST00000261994.4
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr4_+_159131346 0.02 ENST00000508243.1
ENST00000296529.6
TMEM144
transmembrane protein 144
chr11_-_108438847 0.02 ENST00000531386.1
EXPH5
exophilin 5
chr19_+_37464063 0.02 ENST00000586353.1
ENST00000433993.1
ENST00000592567.1
ZNF568
zinc finger protein 568
chr10_-_103603568 0.02 ENST00000356640.2
KCNIP2
Kv channel interacting protein 2
chr12_-_11036844 0.02 ENST00000428168.2
PRH1
proline-rich protein HaeIII subfamily 1
chr12_-_58135903 0.02 ENST00000257897.3
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr16_+_68279256 0.02 ENST00000564827.2
ENST00000566188.1
ENST00000444212.2
ENST00000568082.1
PLA2G15
phospholipase A2, group XV
chr11_-_111794446 0.02 ENST00000527950.1
CRYAB
crystallin, alpha B
chr1_+_87595497 0.02 ENST00000471417.1
RP5-1052I5.1
long intergenic non-protein coding RNA 1140
chr2_-_207630033 0.02 ENST00000449792.1
MDH1B
malate dehydrogenase 1B, NAD (soluble)
chr1_+_54703710 0.02 ENST00000361350.4
SSBP3-AS1
SSBP3 antisense RNA 1
chr6_-_35656685 0.02 ENST00000539068.1
ENST00000540787.1
FKBP5
FK506 binding protein 5
chr1_+_174670143 0.02 ENST00000367687.1
ENST00000347255.2
RABGAP1L
RAB GTPase activating protein 1-like
chr21_+_35736302 0.02 ENST00000290310.3
KCNE2
potassium voltage-gated channel, Isk-related family, member 2
chr3_-_155011483 0.02 ENST00000489090.1
RP11-451G4.2
RP11-451G4.2
chr4_-_860950 0.02 ENST00000511980.1
ENST00000510799.1
GAK
cyclin G associated kinase
chr2_-_150444300 0.02 ENST00000303319.5
MMADHC
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr5_+_81575281 0.02 ENST00000380167.4
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr6_-_11779174 0.02 ENST00000379413.2
ADTRP
androgen-dependent TFPI-regulating protein
chr19_-_50836762 0.02 ENST00000474951.1
ENST00000391818.2
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr6_-_35656712 0.02 ENST00000357266.4
ENST00000542713.1
FKBP5
FK506 binding protein 5
chr19_-_11457162 0.02 ENST00000590482.1
TMEM205
transmembrane protein 205
chr13_+_28712614 0.02 ENST00000380958.3
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr7_-_123198284 0.02 ENST00000355749.2
NDUFA5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr12_+_104680793 0.02 ENST00000529546.1
ENST00000529751.1
ENST00000540716.1
ENST00000528079.2
ENST00000526580.1
TXNRD1
thioredoxin reductase 1
chr12_-_118796971 0.02 ENST00000542902.1
TAOK3
TAO kinase 3
chr3_+_184529948 0.02 ENST00000436792.2
ENST00000446204.2
ENST00000422105.1
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr2_-_158732340 0.02 ENST00000539637.1
ENST00000413751.1
ENST00000434821.1
ENST00000424669.1
ACVR1
activin A receptor, type I
chr5_-_133304473 0.02 ENST00000231512.3
C5orf15
chromosome 5 open reading frame 15
chr19_+_47523058 0.02 ENST00000602212.1
ENST00000602189.1
NPAS1
neuronal PAS domain protein 1
chr19_+_36632204 0.02 ENST00000592354.1
CAPNS1
calpain, small subunit 1
chr22_+_21321531 0.02 ENST00000405089.1
ENST00000335375.5
AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr19_+_11457175 0.02 ENST00000458408.1
ENST00000586451.1
ENST00000588592.1
CCDC159
coiled-coil domain containing 159
chr12_+_16500037 0.02 ENST00000536371.1
ENST00000010404.2
MGST1
microsomal glutathione S-transferase 1
chr12_-_110883346 0.02 ENST00000547365.1
ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr11_+_933555 0.02 ENST00000534485.1
AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr1_+_26737292 0.02 ENST00000254231.4
LIN28A
lin-28 homolog A (C. elegans)
chr2_+_61404624 0.02 ENST00000394457.3
AHSA2
AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast)
chr19_-_3600549 0.02 ENST00000589966.1
TBXA2R
thromboxane A2 receptor
chr1_-_44818599 0.02 ENST00000537474.1
ERI3
ERI1 exoribonuclease family member 3
chr4_+_26165074 0.02 ENST00000512351.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chrX_+_152907913 0.02 ENST00000370167.4
DUSP9
dual specificity phosphatase 9
chr12_-_323689 0.02 ENST00000428720.1
SLC6A12
solute carrier family 6 (neurotransmitter transporter), member 12
chr16_+_2303738 0.02 ENST00000454671.1
AC009065.1
Uncharacterized protein
chr6_-_159466042 0.02 ENST00000338313.5
TAGAP
T-cell activation RhoGTPase activating protein
chr5_+_140201183 0.02 ENST00000529619.1
ENST00000529859.1
ENST00000378126.3
PCDHA5
protocadherin alpha 5
chr15_+_89631381 0.02 ENST00000352732.5
ABHD2
abhydrolase domain containing 2
chr10_-_96122682 0.02 ENST00000371361.3
NOC3L
nucleolar complex associated 3 homolog (S. cerevisiae)
chr11_+_58874701 0.02 ENST00000529618.1
ENST00000534403.1
ENST00000343597.3
FAM111B
family with sequence similarity 111, member B
chr16_+_11343475 0.02 ENST00000572173.1
RMI2
RecQ mediated genome instability 2
chr12_+_26205496 0.02 ENST00000537946.1
ENST00000541218.1
ENST00000282884.9
ENST00000545413.1
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr10_+_104613980 0.02 ENST00000339834.5
C10orf32
chromosome 10 open reading frame 32

Network of associatons between targets according to the STRING database.

First level regulatory network of SIX1_SIX3_SIX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.0 GO:0090472 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.0 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.0 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.0 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)