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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SHOX2_HOXC5

Z-value: 1.11

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Transcription factors associated with SHOX2_HOXC5

Gene Symbol Gene ID Gene Info
SHOX2
ENSG00000168779.15 short stature homeobox 2
HOXC5
ENSG00000172789.3 homeobox C5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SHOX2hg19_v2_chr3_-_157823839_1578240780.739.6e-02Click!
HOXC5hg19_v2_chr12_+_54426637_544266370.562.5e-01Click!

Activity profile of SHOX2_HOXC5 motif

Sorted Z-values of SHOX2_HOXC5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_119669160 1.04 ENST00000514240.1
CTC-552D5.1
CTC-552D5.1
chr11_-_104817919 0.90 ENST00000533252.1
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr1_+_81001398 0.79 ENST00000418041.1
ENST00000443104.1
RP5-887A10.1
RP5-887A10.1
chr8_-_65730127 0.66 ENST00000522106.1
RP11-1D12.2
RP11-1D12.2
chr22_+_46476192 0.62 ENST00000443490.1
FLJ27365
hsa-mir-4763
chr8_+_105235572 0.56 ENST00000523362.1
RIMS2
regulating synaptic membrane exocytosis 2
chr5_-_126409159 0.56 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
C5orf63
chromosome 5 open reading frame 63
chr13_-_46742630 0.56 ENST00000416500.1
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr2_-_55496476 0.55 ENST00000441307.1
MTIF2
mitochondrial translational initiation factor 2
chrX_+_13671225 0.52 ENST00000545566.1
ENST00000544987.1
ENST00000314720.4
TCEANC
transcription elongation factor A (SII) N-terminal and central domain containing
chr10_+_6779326 0.50 ENST00000417112.1
RP11-554I8.2
RP11-554I8.2
chr11_+_29181503 0.49 ENST00000530960.1
RP11-466I1.1
RP11-466I1.1
chr16_+_77756399 0.49 ENST00000564085.1
ENST00000268533.5
ENST00000568787.1
ENST00000437314.3
ENST00000563839.1
NUDT7
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr4_+_75174204 0.49 ENST00000332112.4
ENST00000514968.1
ENST00000503098.1
ENST00000502358.1
ENST00000509145.1
ENST00000505212.1
EPGN
epithelial mitogen
chr1_+_51434357 0.49 ENST00000396148.1
CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr11_-_104916034 0.48 ENST00000528513.1
ENST00000375706.2
ENST00000375704.3
CARD16
caspase recruitment domain family, member 16
chr19_+_36239576 0.47 ENST00000587751.1
LIN37
lin-37 homolog (C. elegans)
chr12_-_85430024 0.43 ENST00000547836.1
ENST00000532498.2
TSPAN19
tetraspanin 19
chr2_-_70352421 0.41 ENST00000414141.1
AC016700.5
AC016700.5
chr6_-_32557610 0.41 ENST00000360004.5
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
chr8_+_55466915 0.39 ENST00000522711.2
RP11-53M11.3
RP11-53M11.3
chr14_-_73997901 0.37 ENST00000557603.1
ENST00000556455.1
HEATR4
HEAT repeat containing 4
chr20_+_5731083 0.36 ENST00000445603.1
ENST00000442185.1
C20orf196
chromosome 20 open reading frame 196
chrM_-_14670 0.36 ENST00000361681.2
MT-ND6
mitochondrially encoded NADH dehydrogenase 6
chr1_+_81106951 0.35 ENST00000443565.1
RP5-887A10.1
RP5-887A10.1
chr8_-_25281747 0.35 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr11_-_96239990 0.34 ENST00000511243.2
JRKL-AS1
JRKL antisense RNA 1
chr6_+_130339710 0.34 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr3_+_28390637 0.34 ENST00000420223.1
ENST00000383768.2
ZCWPW2
zinc finger, CW type with PWWP domain 2
chr1_+_87012922 0.34 ENST00000263723.5
CLCA4
chloride channel accessory 4
chr6_-_170151603 0.33 ENST00000366774.3
TCTE3
t-complex-associated-testis-expressed 3
chr5_+_53751445 0.33 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr11_+_27015628 0.33 ENST00000318627.2
FIBIN
fin bud initiation factor homolog (zebrafish)
chr12_-_64062583 0.33 ENST00000542209.1
DPY19L2
dpy-19-like 2 (C. elegans)
chr1_-_204135450 0.32 ENST00000272190.8
ENST00000367195.2
REN
renin
chr2_+_232316906 0.32 ENST00000370380.2
AC017104.2
Uncharacterized protein
chr21_-_31538971 0.31 ENST00000286808.3
CLDN17
claudin 17
chr5_+_55147205 0.31 ENST00000396836.2
ENST00000396834.1
ENST00000447346.2
ENST00000359040.5
IL31RA
interleukin 31 receptor A
chr4_-_69434245 0.31 ENST00000317746.2
UGT2B17
UDP glucuronosyltransferase 2 family, polypeptide B17
chr17_-_4938712 0.31 ENST00000254853.5
ENST00000424747.1
SLC52A1
solute carrier family 52 (riboflavin transporter), member 1
chr17_+_61473104 0.30 ENST00000583016.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr1_-_179457805 0.30 ENST00000600581.1
AL160286.1
Uncharacterized protein
chr9_-_75488984 0.30 ENST00000423171.1
ENST00000449235.1
ENST00000453787.1
RP11-151D14.1
RP11-151D14.1
chr7_-_77325545 0.30 ENST00000447009.1
ENST00000416650.1
ENST00000440088.1
ENST00000430801.1
ENST00000398043.2
RSBN1L-AS1
RSBN1L antisense RNA 1
chr3_-_69590486 0.30 ENST00000497880.1
FRMD4B
FERM domain containing 4B
chr5_-_94417339 0.29 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1
multiple C2 domains, transmembrane 1
chr12_-_8803128 0.29 ENST00000543467.1
MFAP5
microfibrillar associated protein 5
chr11_+_327171 0.29 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12
RP11-326C3.12
chr4_+_87857538 0.28 ENST00000511442.1
AFF1
AF4/FMR2 family, member 1
chr4_+_147145709 0.28 ENST00000504313.1
RP11-6L6.2
Uncharacterized protein
chr12_-_112123524 0.27 ENST00000327551.6
BRAP
BRCA1 associated protein
chr12_-_25150409 0.27 ENST00000549262.1
C12orf77
chromosome 12 open reading frame 77
chr6_-_38670897 0.27 ENST00000373365.4
GLO1
glyoxalase I
chr12_-_25348007 0.27 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
CASC1
cancer susceptibility candidate 1
chr8_-_7287870 0.27 ENST00000318124.3
DEFB103B
defensin, beta 103B
chr12_-_15114658 0.27 ENST00000542276.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr14_-_69864993 0.27 ENST00000555373.1
ERH
enhancer of rudimentary homolog (Drosophila)
chr4_-_19458597 0.27 ENST00000505347.1
RP11-3J1.1
RP11-3J1.1
chr17_+_19091325 0.27 ENST00000584923.1
SNORD3A
small nucleolar RNA, C/D box 3A
chr2_+_113763031 0.27 ENST00000259211.6
IL36A
interleukin 36, alpha
chr16_+_1359511 0.26 ENST00000397514.3
ENST00000397515.2
ENST00000567383.1
ENST00000403747.2
ENST00000566587.1
UBE2I
ubiquitin-conjugating enzyme E2I
chr3_+_52245458 0.26 ENST00000459884.1
ALAS1
aminolevulinate, delta-, synthase 1
chr11_-_124981475 0.26 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
TMEM218
transmembrane protein 218
chr3_-_150421752 0.26 ENST00000498386.1
FAM194A
family with sequence similarity 194, member A
chr16_-_28634874 0.26 ENST00000395609.1
ENST00000350842.4
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr7_-_111032971 0.25 ENST00000450877.1
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr22_+_23487513 0.25 ENST00000263116.2
ENST00000341989.4
RAB36
RAB36, member RAS oncogene family
chr17_-_77005813 0.25 ENST00000590370.1
ENST00000591625.1
CANT1
calcium activated nucleotidase 1
chr6_+_31021225 0.25 ENST00000565192.1
ENST00000562344.1
HCG22
HLA complex group 22
chr2_-_136633940 0.25 ENST00000264156.2
MCM6
minichromosome maintenance complex component 6
chr16_-_66583701 0.25 ENST00000527800.1
ENST00000525974.1
ENST00000563369.2
TK2
thymidine kinase 2, mitochondrial
chr5_-_20575959 0.25 ENST00000507958.1
CDH18
cadherin 18, type 2
chr11_+_27076764 0.25 ENST00000525090.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr12_-_22063787 0.25 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr18_+_52385068 0.25 ENST00000586570.1
RAB27B
RAB27B, member RAS oncogene family
chr11_-_46408107 0.25 ENST00000433765.2
CHRM4
cholinergic receptor, muscarinic 4
chr16_-_66583994 0.25 ENST00000564917.1
TK2
thymidine kinase 2, mitochondrial
chr16_+_27226256 0.25 ENST00000567735.1
KDM8
lysine (K)-specific demethylase 8
chr16_-_28608424 0.24 ENST00000335715.4
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr19_-_55150343 0.24 ENST00000456337.1
AC009892.10
Uncharacterized protein
chr13_+_37581115 0.24 ENST00000481013.1
EXOSC8
exosome component 8
chr11_+_110225855 0.24 ENST00000526605.1
ENST00000526703.1
RP11-347E10.1
RP11-347E10.1
chr16_-_30122717 0.24 ENST00000566613.1
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr16_-_66584059 0.24 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
TK2
thymidine kinase 2, mitochondrial
chr9_+_108463234 0.24 ENST00000374688.1
TMEM38B
transmembrane protein 38B
chr2_-_114461655 0.24 ENST00000424612.1
AC017074.2
AC017074.2
chr6_+_52442083 0.24 ENST00000606714.1
TRAM2-AS1
TRAM2 antisense RNA 1 (head to head)
chr19_-_58951496 0.24 ENST00000254166.3
ZNF132
zinc finger protein 132
chr18_-_67624412 0.24 ENST00000580335.1
CD226
CD226 molecule
chr1_+_160709055 0.23 ENST00000368043.3
ENST00000368042.3
ENST00000458602.2
ENST00000458104.2
SLAMF7
SLAM family member 7
chr20_+_18548055 0.23 ENST00000435844.1
ENST00000411646.1
ENST00000608034.1
LINC00493
long intergenic non-protein coding RNA 493
chr11_-_105010320 0.23 ENST00000532895.1
ENST00000530950.1
CARD18
caspase recruitment domain family, member 18
chr18_-_59274139 0.23 ENST00000586949.1
RP11-879F14.2
RP11-879F14.2
chr10_+_5454505 0.23 ENST00000355029.4
NET1
neuroepithelial cell transforming 1
chr12_-_11548496 0.23 ENST00000389362.4
ENST00000565533.1
ENST00000546254.1
PRB2
PRB1
proline-rich protein BstNI subfamily 2
proline-rich protein BstNI subfamily 1
chrX_-_100662881 0.23 ENST00000218516.3
GLA
galactosidase, alpha
chr6_+_160542870 0.23 ENST00000324965.4
ENST00000457470.2
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr19_+_54466179 0.23 ENST00000270458.2
CACNG8
calcium channel, voltage-dependent, gamma subunit 8
chr8_-_86290333 0.23 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
CA1
carbonic anhydrase I
chr1_-_92952433 0.23 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr2_-_74618907 0.22 ENST00000421392.1
ENST00000437375.1
DCTN1
dynactin 1
chr3_+_37035289 0.22 ENST00000455445.2
ENST00000441265.1
ENST00000435176.1
ENST00000429117.1
ENST00000536378.1
MLH1
mutL homolog 1
chr17_+_67498538 0.22 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr21_-_30257669 0.22 ENST00000303775.5
ENST00000351429.3
N6AMT1
N-6 adenine-specific DNA methyltransferase 1 (putative)
chr10_-_128110441 0.22 ENST00000456514.1
LINC00601
long intergenic non-protein coding RNA 601
chr12_-_15038779 0.22 ENST00000228938.5
ENST00000539261.1
MGP
matrix Gla protein
chr9_-_28670283 0.22 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chr14_-_100841794 0.22 ENST00000556295.1
ENST00000554820.1
WARS
tryptophanyl-tRNA synthetase
chr2_-_134326009 0.21 ENST00000409261.1
ENST00000409213.1
NCKAP5
NCK-associated protein 5
chr8_-_38008783 0.21 ENST00000276449.4
STAR
steroidogenic acute regulatory protein
chr6_+_160542821 0.21 ENST00000366963.4
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr7_-_22862406 0.21 ENST00000372879.4
TOMM7
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr12_+_90674665 0.21 ENST00000549313.1
RP11-753N8.1
RP11-753N8.1
chrM_+_10758 0.21 ENST00000361381.2
MT-ND4
mitochondrially encoded NADH dehydrogenase 4
chr9_+_117904097 0.20 ENST00000374016.1
DEC1
deleted in esophageal cancer 1
chr12_+_34175398 0.20 ENST00000538927.1
ALG10
ALG10, alpha-1,2-glucosyltransferase
chr1_+_225600404 0.20 ENST00000366845.2
AC092811.1
AC092811.1
chr5_-_10761206 0.20 ENST00000432074.2
ENST00000230895.6
DAP
death-associated protein
chr11_+_35201826 0.20 ENST00000531873.1
CD44
CD44 molecule (Indian blood group)
chr5_-_94417562 0.20 ENST00000505465.1
MCTP1
multiple C2 domains, transmembrane 1
chr17_-_72588422 0.20 ENST00000375352.1
CD300LD
CD300 molecule-like family member d
chr6_+_139349903 0.20 ENST00000461027.1
ABRACL
ABRA C-terminal like
chr14_-_104387888 0.20 ENST00000286953.3
C14orf2
chromosome 14 open reading frame 2
chr1_+_160709076 0.20 ENST00000359331.4
ENST00000495334.1
SLAMF7
SLAM family member 7
chr8_+_70476088 0.19 ENST00000525999.1
SULF1
sulfatase 1
chr1_-_201140673 0.19 ENST00000367333.2
TMEM9
transmembrane protein 9
chr11_+_33061543 0.19 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1
t-complex 11, testis-specific-like 1
chr17_-_19015945 0.19 ENST00000573866.2
SNORD3D
small nucleolar RNA, C/D box 3D
chr18_-_74839891 0.19 ENST00000581878.1
MBP
myelin basic protein
chr2_+_27886330 0.19 ENST00000326019.6
SLC4A1AP
solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr17_-_18950950 0.19 ENST00000284154.5
GRAP
GRB2-related adaptor protein
chr13_+_111748183 0.18 ENST00000422994.1
LINC00368
long intergenic non-protein coding RNA 368
chr22_-_40929812 0.18 ENST00000422851.1
MKL1
megakaryoblastic leukemia (translocation) 1
chrX_+_107334983 0.18 ENST00000457035.1
ENST00000545696.1
ATG4A
autophagy related 4A, cysteine peptidase
chr20_-_33735070 0.18 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chrX_+_55744166 0.18 ENST00000374941.4
ENST00000414239.1
RRAGB
Ras-related GTP binding B
chr11_-_107729887 0.18 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr2_+_102953608 0.17 ENST00000311734.2
ENST00000409584.1
IL1RL1
interleukin 1 receptor-like 1
chr6_+_26204825 0.17 ENST00000360441.4
HIST1H4E
histone cluster 1, H4e
chr1_+_212965170 0.17 ENST00000532324.1
ENST00000366974.4
ENST00000530441.1
ENST00000526641.1
ENST00000531963.1
ENST00000366973.4
ENST00000526997.1
ENST00000488246.2
TATDN3
TatD DNase domain containing 3
chr5_+_140514782 0.17 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr17_+_66511540 0.17 ENST00000588188.2
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr7_+_141438118 0.17 ENST00000265304.6
ENST00000498107.1
ENST00000467681.1
ENST00000465582.1
ENST00000463093.1
SSBP1
single-stranded DNA binding protein 1, mitochondrial
chr1_+_160709029 0.17 ENST00000444090.2
ENST00000441662.2
SLAMF7
SLAM family member 7
chr10_+_35484793 0.17 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr9_+_131684027 0.17 ENST00000426694.1
PHYHD1
phytanoyl-CoA dioxygenase domain containing 1
chr15_+_77713222 0.17 ENST00000558176.1
HMG20A
high mobility group 20A
chr1_-_54483842 0.17 ENST00000371362.3
ENST00000420619.1
LDLRAD1
low density lipoprotein receptor class A domain containing 1
chrX_+_19362011 0.17 ENST00000379806.5
ENST00000545074.1
ENST00000540249.1
ENST00000423505.1
ENST00000417819.1
ENST00000422285.2
ENST00000355808.5
ENST00000379805.3
PDHA1
pyruvate dehydrogenase (lipoamide) alpha 1
chr19_+_41281416 0.17 ENST00000597140.1
MIA
melanoma inhibitory activity
chr3_+_187930491 0.17 ENST00000443217.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr11_+_122733011 0.17 ENST00000533709.1
CRTAM
cytotoxic and regulatory T cell molecule
chr8_+_134125727 0.17 ENST00000521107.1
TG
thyroglobulin
chr19_-_54824344 0.17 ENST00000346508.3
ENST00000446712.3
ENST00000432233.3
ENST00000301219.3
LILRA5
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
chr19_-_2944907 0.17 ENST00000314531.4
ZNF77
zinc finger protein 77
chr9_-_23779367 0.17 ENST00000440102.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chrM_+_10464 0.17 ENST00000361335.1
MT-ND4L
mitochondrially encoded NADH dehydrogenase 4L
chr14_+_74486043 0.17 ENST00000464394.1
ENST00000394009.3
CCDC176
coiled-coil domain containing 176
chr4_+_169418255 0.17 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr14_-_70883708 0.17 ENST00000256366.4
SYNJ2BP
synaptojanin 2 binding protein
chr7_+_120591170 0.17 ENST00000431467.1
ING3
inhibitor of growth family, member 3
chr19_-_47104118 0.16 ENST00000593888.1
ENST00000602017.1
AC011551.3
PPP5D1
Uncharacterized protein
PPP5 tetratricopeptide repeat domain containing 1
chr19_-_51327034 0.16 ENST00000301420.2
ENST00000448701.2
KLK1
kallikrein 1
chr21_-_31852663 0.16 ENST00000390689.2
KRTAP19-1
keratin associated protein 19-1
chr5_+_42756903 0.16 ENST00000361970.5
ENST00000388827.4
CCDC152
coiled-coil domain containing 152
chr17_-_6543973 0.16 ENST00000571642.1
ENST00000572370.1
KIAA0753
KIAA0753
chr13_-_30160925 0.16 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr5_-_81574160 0.16 ENST00000510210.1
ENST00000512493.1
ENST00000507980.1
ENST00000511844.1
ENST00000510019.1
RPS23
ribosomal protein S23
chr3_+_185431080 0.16 ENST00000296270.1
C3orf65
chromosome 3 open reading frame 65
chr18_-_47018869 0.16 ENST00000583036.1
ENST00000580261.1
RPL17
ribosomal protein L17
chr12_+_106751436 0.16 ENST00000228347.4
POLR3B
polymerase (RNA) III (DNA directed) polypeptide B
chr6_+_148663729 0.16 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1
chr4_-_17513604 0.15 ENST00000505710.1
QDPR
quinoid dihydropteridine reductase
chr4_-_299110 0.15 ENST00000419098.1
ZNF732
zinc finger protein 732
chr12_-_112279694 0.15 ENST00000443596.1
ENST00000442119.1
MAPKAPK5-AS1
MAPKAPK5 antisense RNA 1
chr17_+_41150290 0.15 ENST00000589037.1
ENST00000253788.5
RPL27
ribosomal protein L27
chr19_-_51920952 0.15 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
SIGLEC10
sialic acid binding Ig-like lectin 10
chr15_+_75639372 0.15 ENST00000566313.1
ENST00000568059.1
ENST00000568881.1
NEIL1
nei endonuclease VIII-like 1 (E. coli)
chr14_-_54423529 0.15 ENST00000245451.4
ENST00000559087.1
BMP4
bone morphogenetic protein 4
chr11_-_128894053 0.15 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr12_-_56321397 0.15 ENST00000557259.1
ENST00000549939.1
WIBG
within bgcn homolog (Drosophila)
chr14_-_20801427 0.15 ENST00000557665.1
ENST00000358932.4
ENST00000353689.4
CCNB1IP1
cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
chr5_+_60933634 0.15 ENST00000505642.1
C5orf64
chromosome 5 open reading frame 64
chr15_-_100273544 0.15 ENST00000409796.1
ENST00000545021.1
ENST00000344791.2
ENST00000332728.4
ENST00000450512.1
LYSMD4
LysM, putative peptidoglycan-binding, domain containing 4
chr18_-_47018897 0.15 ENST00000418495.1
RPL17
ribosomal protein L17
chr7_-_7679633 0.15 ENST00000401447.1
RPA3
replication protein A3, 14kDa
chr17_+_67498396 0.15 ENST00000588110.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr11_+_62496114 0.15 ENST00000532583.1
TTC9C
tetratricopeptide repeat domain 9C
chr2_+_183982238 0.15 ENST00000442895.2
ENST00000446612.1
ENST00000409798.1
NUP35
nucleoporin 35kDa
chr3_+_138153451 0.15 ENST00000389567.4
ENST00000289135.4
ESYT3
extended synaptotagmin-like protein 3
chr12_+_7013897 0.15 ENST00000007969.8
ENST00000323702.5
LRRC23
leucine rich repeat containing 23
chr16_-_75467274 0.15 ENST00000566254.1
CFDP1
craniofacial development protein 1
chr17_-_4710288 0.14 ENST00000571067.1
RP11-81A22.5
RP11-81A22.5
chr17_-_71258491 0.14 ENST00000397671.1
CPSF4L
cleavage and polyadenylation specific factor 4-like
chr11_+_122753391 0.14 ENST00000307257.6
ENST00000227349.2
C11orf63
chromosome 11 open reading frame 63
chr6_+_28092338 0.14 ENST00000340487.4
ZSCAN16
zinc finger and SCAN domain containing 16
chr10_+_96522361 0.14 ENST00000371321.3
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr2_+_219472488 0.14 ENST00000450993.2
PLCD4
phospholipase C, delta 4
chr5_-_147286065 0.14 ENST00000318315.4
ENST00000515291.1
C5orf46
chromosome 5 open reading frame 46
chr12_-_91546926 0.14 ENST00000550758.1
DCN
decorin

Network of associatons between targets according to the STRING database.

First level regulatory network of SHOX2_HOXC5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0046356 acetyl-CoA catabolic process(GO:0046356)
0.1 0.7 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.1 0.4 GO:0051257 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.1 0.5 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 0.5 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.1 1.0 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.4 GO:1990637 response to prolactin(GO:1990637)
0.1 0.4 GO:0048241 epinephrine transport(GO:0048241)
0.1 0.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.2 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.4 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.3 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.2 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1 0.1 GO:1904640 response to methionine(GO:1904640)
0.1 0.4 GO:0071494 cellular response to UV-C(GO:0071494)
0.1 0.2 GO:0018963 insecticide metabolic process(GO:0017143) phthalate metabolic process(GO:0018963) cellular response to luteinizing hormone stimulus(GO:0071373)
0.1 0.1 GO:1904875 regulation of DNA ligase activity(GO:1904875)
0.0 0.3 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.6 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.3 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.2 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.2 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.2 GO:0060434 bronchus morphogenesis(GO:0060434)
0.0 0.1 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.2 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.3 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.0 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.2 GO:0036511 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.1 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.3 GO:0035932 mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) drinking behavior(GO:0042756) regulation of mineralocorticoid secretion(GO:2000855) regulation of aldosterone secretion(GO:2000858)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.1 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.1 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.3 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.2 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.1 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.4 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.2 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 0.3 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.7 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.1 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.0 0.1 GO:0061571 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 0.3 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.2 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.3 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0099558 maintenance of synapse structure(GO:0099558)
0.0 0.1 GO:0010983 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0 0.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.0 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.0 0.1 GO:2001193 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.1 GO:0039516 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.1 GO:0003277 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.1 GO:0019542 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.1 GO:0019516 lactate oxidation(GO:0019516)
0.0 0.2 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.2 GO:0070777 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.1 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.1 GO:1902948 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.1 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.0 GO:0071284 cellular response to lead ion(GO:0071284)
0.0 0.0 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0042737 drug catabolic process(GO:0042737)
0.0 0.1 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
0.0 0.5 GO:0002438 acute inflammatory response to antigenic stimulus(GO:0002438)
0.0 0.3 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.2 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.2 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.2 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.0 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.1 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.0 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 1.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.2 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.1 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.0 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.2 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.1 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.1 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.0 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.0 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.0 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.1 GO:0042182 ketone catabolic process(GO:0042182)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.3 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.2 GO:0051451 myoblast migration(GO:0051451)
0.0 0.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.0 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.2 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.2 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.1 GO:0009233 menaquinone metabolic process(GO:0009233)
0.0 0.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.0 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.1 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:1902306 negative regulation of sodium ion transmembrane transport(GO:1902306)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.5 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.0 0.1 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.1 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.1 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.4 GO:0005715 late recombination nodule(GO:0005715)
0.1 0.4 GO:0097179 protease inhibitor complex(GO:0097179)
0.1 0.3 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.4 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.2 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.0 0.3 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.2 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.2 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993)
0.0 0.3 GO:0034709 methylosome(GO:0034709)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.0 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.5 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.0 GO:0060187 cell pole(GO:0060187)
0.0 0.0 GO:0097196 Shu complex(GO:0097196)
0.0 1.2 GO:0070469 respiratory chain(GO:0070469)
0.0 0.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.4 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.1 0.7 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1 0.6 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 0.3 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 1.8 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.3 GO:0043398 HLH domain binding(GO:0043398)
0.1 0.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.3 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.2 GO:0031862 prostanoid receptor binding(GO:0031862)
0.1 0.2 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 0.2 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.2 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1 0.2 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.3 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.2 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.4 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.2 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.1 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0 0.1 GO:0004145 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.0 0.3 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.6 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0070404 NADH binding(GO:0070404)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0030109 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107) HLA-B specific inhibitory MHC class I receptor activity(GO:0030109) inhibitory MHC class I receptor activity(GO:0032396)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.1 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.1 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505) 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.1 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 1.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.0 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.0 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266)
0.0 0.0 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.0 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.0 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.0 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.4 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.0 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.1 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 0.0 GO:0004132 dCMP deaminase activity(GO:0004132)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.0 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.3 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling