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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SCRT1_SCRT2

Z-value: 1.14

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Transcription factors associated with SCRT1_SCRT2

Gene Symbol Gene ID Gene Info
SCRT1
ENSG00000170616.9 scratch family transcriptional repressor 1
SCRT2
ENSG00000215397.3 scratch family transcriptional repressor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SCRT1hg19_v2_chr8_-_145559943_145559943-0.167.6e-01Click!

Activity profile of SCRT1_SCRT2 motif

Sorted Z-values of SCRT1_SCRT2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_165675197 1.40 ENST00000515485.1
RP11-294O2.2
RP11-294O2.2
chr4_-_6675550 0.85 ENST00000513179.1
ENST00000515205.1
RP11-539L10.3
RP11-539L10.3
chr9_+_69650263 0.58 ENST00000322495.3
AL445665.1
Protein LOC100996643
chr4_+_165675269 0.55 ENST00000507311.1
RP11-294O2.2
RP11-294O2.2
chr8_-_110988070 0.52 ENST00000524391.1
KCNV1
potassium channel, subfamily V, member 1
chr3_+_181429704 0.48 ENST00000431565.2
ENST00000325404.1
SOX2
SRY (sex determining region Y)-box 2
chr15_+_76352178 0.47 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr13_+_96743093 0.46 ENST00000376705.2
HS6ST3
heparan sulfate 6-O-sulfotransferase 3
chr14_-_81902516 0.42 ENST00000554710.1
STON2
stonin 2
chr8_-_33330595 0.41 ENST00000524021.1
ENST00000335589.3
FUT10
fucosyltransferase 10 (alpha (1,3) fucosyltransferase)
chr22_-_22090043 0.41 ENST00000403503.1
YPEL1
yippee-like 1 (Drosophila)
chr16_-_30022293 0.40 ENST00000565273.1
ENST00000567332.2
ENST00000350119.4
DOC2A
double C2-like domains, alpha
chr5_-_73936544 0.40 ENST00000509127.2
ENC1
ectodermal-neural cortex 1 (with BTB domain)
chrX_+_55744228 0.38 ENST00000262850.7
RRAGB
Ras-related GTP binding B
chr1_-_219615984 0.37 ENST00000420762.1
RP11-95P13.1
RP11-95P13.1
chr10_+_35484793 0.35 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr14_-_81902791 0.35 ENST00000557055.1
STON2
stonin 2
chr17_-_39258461 0.34 ENST00000440582.1
KRTAP4-16P
keratin associated protein 4-16, pseudogene
chr13_+_20268547 0.34 ENST00000601204.1
AL354808.2
AL354808.2
chr20_-_50159198 0.32 ENST00000371564.3
ENST00000396009.3
ENST00000610033.1
NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr1_+_156308245 0.32 ENST00000368253.2
ENST00000470342.1
ENST00000368254.1
TSACC
TSSK6 activating co-chaperone
chr1_+_33283043 0.32 ENST00000373476.1
ENST00000373475.5
ENST00000529027.1
ENST00000398243.3
S100PBP
S100P binding protein
chr1_-_95392635 0.30 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
CNN3
calponin 3, acidic
chr1_+_222791417 0.29 ENST00000344922.5
ENST00000344441.6
ENST00000344507.1
MIA3
melanoma inhibitory activity family, member 3
chr5_+_15500280 0.28 ENST00000504595.1
FBXL7
F-box and leucine-rich repeat protein 7
chr6_-_27440460 0.28 ENST00000377419.1
ZNF184
zinc finger protein 184
chr1_-_33283754 0.28 ENST00000373477.4
YARS
tyrosyl-tRNA synthetase
chr16_-_25122785 0.27 ENST00000563962.1
ENST00000569920.1
RP11-449H11.1
RP11-449H11.1
chr15_-_76352069 0.27 ENST00000305435.10
ENST00000563910.1
NRG4
neuregulin 4
chr17_+_19920456 0.26 ENST00000582604.1
SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr6_-_27440837 0.26 ENST00000211936.6
ZNF184
zinc finger protein 184
chr12_+_96337061 0.25 ENST00000266736.2
AMDHD1
amidohydrolase domain containing 1
chr17_+_78194205 0.25 ENST00000573809.1
ENST00000361193.3
ENST00000574967.1
ENST00000576126.1
ENST00000411502.3
ENST00000546047.2
SLC26A11
solute carrier family 26 (anion exchanger), member 11
chr5_-_73936451 0.25 ENST00000537006.1
ENC1
ectodermal-neural cortex 1 (with BTB domain)
chr4_-_90757364 0.25 ENST00000508895.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr8_+_98881268 0.24 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
MATN2
matrilin 2
chr5_-_59064458 0.24 ENST00000502575.1
ENST00000507116.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_+_12726623 0.23 ENST00000439721.1
ARL4A
ADP-ribosylation factor-like 4A
chr11_+_44748361 0.23 ENST00000533202.1
ENST00000533080.1
ENST00000520358.2
ENST00000520999.2
TSPAN18
tetraspanin 18
chr15_-_30114231 0.22 ENST00000356107.6
ENST00000545208.2
TJP1
tight junction protein 1
chr3_+_32280159 0.22 ENST00000458535.2
ENST00000307526.3
CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr15_-_98646940 0.22 ENST00000560195.1
CTD-2544M6.2
CTD-2544M6.2
chr16_-_103572 0.22 ENST00000293860.5
POLR3K
polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
chr1_+_109289279 0.22 ENST00000370008.3
STXBP3
syntaxin binding protein 3
chr7_+_154795154 0.22 ENST00000608317.1
PAXIP1-AS1
PAXIP1 antisense RNA 1 (head to head)
chr3_-_139195350 0.21 ENST00000232217.2
RBP2
retinol binding protein 2, cellular
chr1_-_104239302 0.21 ENST00000446703.1
AMY1B
amylase, alpha 1B (salivary)
chr1_+_104197912 0.21 ENST00000430659.1
AMY1A
amylase, alpha 1A (salivary)
chr9_+_125703282 0.21 ENST00000373647.4
ENST00000402311.1
RABGAP1
RAB GTPase activating protein 1
chr19_-_5838734 0.20 ENST00000532464.1
ENST00000528505.1
FUT6
fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
chr1_+_16083123 0.20 ENST00000510393.1
ENST00000430076.1
FBLIM1
filamin binding LIM protein 1
chr12_-_33049690 0.19 ENST00000070846.6
ENST00000340811.4
PKP2
plakophilin 2
chr16_+_67063855 0.19 ENST00000563939.2
CBFB
core-binding factor, beta subunit
chr2_-_24583314 0.19 ENST00000443927.1
ENST00000406921.3
ENST00000412011.1
ITSN2
intersectin 2
chr4_-_120133661 0.18 ENST00000503243.1
ENST00000326780.3
RP11-455G16.1
Uncharacterized protein
chr2_-_224467093 0.18 ENST00000305409.2
SCG2
secretogranin II
chr15_+_63889577 0.17 ENST00000534939.1
ENST00000539570.3
FBXL22
F-box and leucine-rich repeat protein 22
chr17_-_34257771 0.17 ENST00000394529.3
ENST00000293273.6
RDM1
RAD52 motif 1
chr1_-_21044489 0.17 ENST00000247986.2
KIF17
kinesin family member 17
chr1_-_9129598 0.17 ENST00000535586.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr3_-_42846021 0.17 ENST00000321331.7
HIGD1A
HIG1 hypoxia inducible domain family, member 1A
chr22_+_40742512 0.17 ENST00000454266.2
ENST00000342312.6
ADSL
adenylosuccinate lyase
chr1_+_55271736 0.17 ENST00000358193.3
ENST00000371273.3
C1orf177
chromosome 1 open reading frame 177
chr11_-_85430356 0.17 ENST00000526999.1
SYTL2
synaptotagmin-like 2
chr4_+_41258786 0.17 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr3_-_42845951 0.17 ENST00000418900.2
ENST00000430190.1
HIGD1A
HIG1 hypoxia inducible domain family, member 1A
chr1_-_247335269 0.17 ENST00000543802.2
ENST00000491356.1
ENST00000472531.1
ENST00000340684.6
ZNF124
zinc finger protein 124
chr3_+_151986709 0.16 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
MBNL1
muscleblind-like splicing regulator 1
chr7_+_130126165 0.16 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
MEST
mesoderm specific transcript
chr1_-_104239076 0.16 ENST00000370080.3
AMY1B
amylase, alpha 1B (salivary)
chr15_-_30113676 0.16 ENST00000400011.2
TJP1
tight junction protein 1
chr1_+_156308403 0.16 ENST00000481479.1
ENST00000368252.1
ENST00000466306.1
ENST00000368251.1
TSACC
TSSK6 activating co-chaperone
chr18_+_47087390 0.16 ENST00000583083.1
LIPG
lipase, endothelial
chr9_+_214842 0.16 ENST00000453981.1
ENST00000432829.2
DOCK8
dedicator of cytokinesis 8
chr15_+_63889552 0.16 ENST00000360587.2
FBXL22
F-box and leucine-rich repeat protein 22
chrX_-_134232630 0.16 ENST00000535837.1
ENST00000433425.2
LINC00087
long intergenic non-protein coding RNA 87
chr10_+_6779326 0.16 ENST00000417112.1
RP11-554I8.2
RP11-554I8.2
chr8_-_101718991 0.16 ENST00000517990.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr10_-_95209 0.15 ENST00000332708.5
ENST00000309812.4
TUBB8
tubulin, beta 8 class VIII
chr6_+_90272027 0.15 ENST00000522441.1
ANKRD6
ankyrin repeat domain 6
chr6_-_31080336 0.15 ENST00000259870.3
C6orf15
chromosome 6 open reading frame 15
chr8_+_82644669 0.15 ENST00000297265.4
CHMP4C
charged multivesicular body protein 4C
chr15_-_34628951 0.15 ENST00000397707.2
ENST00000560611.1
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr5_+_173763250 0.15 ENST00000515513.1
ENST00000507361.1
ENST00000510234.1
RP11-267A15.1
RP11-267A15.1
chr1_+_16083098 0.15 ENST00000496928.2
ENST00000508310.1
FBLIM1
filamin binding LIM protein 1
chr14_-_77495007 0.14 ENST00000238647.3
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr15_-_44486632 0.14 ENST00000484674.1
FRMD5
FERM domain containing 5
chr22_+_40742497 0.14 ENST00000216194.7
ADSL
adenylosuccinate lyase
chr1_+_222988464 0.14 ENST00000420335.1
RP11-452F19.3
RP11-452F19.3
chr22_-_22090064 0.14 ENST00000339468.3
YPEL1
yippee-like 1 (Drosophila)
chrX_-_31284974 0.14 ENST00000378702.4
DMD
dystrophin
chr14_+_23776167 0.14 ENST00000554635.1
ENST00000557008.1
BCL2L2
BCL2L2-PABPN1
BCL2-like 2
BCL2L2-PABPN1 readthrough
chr5_+_74011328 0.14 ENST00000513336.1
HEXB
hexosaminidase B (beta polypeptide)
chr1_-_9129631 0.14 ENST00000377414.3
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr21_-_35987438 0.13 ENST00000313806.4
RCAN1
regulator of calcineurin 1
chr19_-_49250054 0.13 ENST00000602105.1
ENST00000332955.2
IZUMO1
izumo sperm-egg fusion 1
chr6_+_121756809 0.12 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr19_-_12624647 0.12 ENST00000455490.1
ZNF709
zinc finger protein 709
chr1_-_151813033 0.12 ENST00000454109.1
C2CD4D
C2 calcium-dependent domain containing 4D
chr1_+_33283246 0.12 ENST00000526230.1
ENST00000531256.1
ENST00000482212.1
S100PBP
S100P binding protein
chr4_-_89619386 0.12 ENST00000323061.5
NAP1L5
nucleosome assembly protein 1-like 5
chr21_-_34852304 0.12 ENST00000542230.2
TMEM50B
transmembrane protein 50B
chr16_-_53537105 0.12 ENST00000568596.1
ENST00000570004.1
ENST00000564497.1
ENST00000300245.4
ENST00000394657.7
AKTIP
AKT interacting protein
chr16_+_2198604 0.12 ENST00000210187.6
RAB26
RAB26, member RAS oncogene family
chr9_+_74526532 0.11 ENST00000486911.2
C9orf85
chromosome 9 open reading frame 85
chr1_-_104238912 0.11 ENST00000330330.5
AMY1B
amylase, alpha 1B (salivary)
chr12_-_15374328 0.11 ENST00000537647.1
RERG
RAS-like, estrogen-regulated, growth inhibitor
chr7_+_130126012 0.10 ENST00000341441.5
MEST
mesoderm specific transcript
chrX_-_31285018 0.10 ENST00000361471.4
DMD
dystrophin
chr11_+_27062272 0.10 ENST00000529202.1
ENST00000533566.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr2_+_149402009 0.10 ENST00000457184.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr5_+_32710736 0.10 ENST00000415685.2
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr16_-_50402690 0.10 ENST00000394689.2
BRD7
bromodomain containing 7
chr7_+_12727250 0.10 ENST00000404894.1
ARL4A
ADP-ribosylation factor-like 4A
chr12_-_122907091 0.10 ENST00000358808.2
ENST00000361654.4
ENST00000539080.1
ENST00000537178.1
CLIP1
CAP-GLY domain containing linker protein 1
chr5_+_138611798 0.10 ENST00000502394.1
MATR3
matrin 3
chr10_+_99894399 0.10 ENST00000298999.3
ENST00000314594.5
R3HCC1L
R3H domain and coiled-coil containing 1-like
chr13_+_39261224 0.10 ENST00000280481.7
FREM2
FRAS1 related extracellular matrix protein 2
chr4_-_108204846 0.09 ENST00000513208.1
DKK2
dickkopf WNT signaling pathway inhibitor 2
chr4_-_149363662 0.09 ENST00000355292.3
ENST00000358102.3
NR3C2
nuclear receptor subfamily 3, group C, member 2
chr4_-_52904425 0.09 ENST00000535450.1
SGCB
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
chr19_+_30097181 0.09 ENST00000586420.1
ENST00000221770.3
ENST00000392279.3
ENST00000590688.1
POP4
processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
chr5_+_138089100 0.09 ENST00000520339.1
ENST00000355078.5
ENST00000302763.7
ENST00000518910.1
CTNNA1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr5_-_151066514 0.09 ENST00000538026.1
ENST00000522348.1
ENST00000521569.1
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr7_-_122526499 0.09 ENST00000412584.2
CADPS2
Ca++-dependent secretion activator 2
chr17_-_1029866 0.09 ENST00000570525.1
ABR
active BCR-related
chr6_+_7107999 0.09 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
RREB1
ras responsive element binding protein 1
chr1_+_44115814 0.09 ENST00000372396.3
KDM4A
lysine (K)-specific demethylase 4A
chr11_+_32112431 0.09 ENST00000054950.3
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chrX_-_31285042 0.09 ENST00000378680.2
ENST00000378723.3
DMD
dystrophin
chr20_-_45061695 0.09 ENST00000445496.2
ELMO2
engulfment and cell motility 2
chr17_-_33760269 0.09 ENST00000452764.3
SLFN12
schlafen family member 12
chr12_+_16500037 0.08 ENST00000536371.1
ENST00000010404.2
MGST1
microsomal glutathione S-transferase 1
chr20_-_23402028 0.08 ENST00000398425.3
ENST00000432543.2
ENST00000377026.4
NAPB
N-ethylmaleimide-sensitive factor attachment protein, beta
chr4_-_83483395 0.08 ENST00000515780.2
TMEM150C
transmembrane protein 150C
chr7_+_138145145 0.08 ENST00000415680.2
TRIM24
tripartite motif containing 24
chr2_-_96192450 0.08 ENST00000609975.1
RP11-440D17.3
RP11-440D17.3
chr16_-_82045049 0.08 ENST00000532128.1
ENST00000328945.5
SDR42E1
short chain dehydrogenase/reductase family 42E, member 1
chr2_-_180726232 0.08 ENST00000410066.1
ZNF385B
zinc finger protein 385B
chr12_+_50794947 0.08 ENST00000552445.1
LARP4
La ribonucleoprotein domain family, member 4
chr19_-_5838768 0.08 ENST00000527106.1
ENST00000531199.1
ENST00000529165.1
FUT6
fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
chr1_-_9129895 0.08 ENST00000473209.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr4_-_149363376 0.08 ENST00000512865.1
NR3C2
nuclear receptor subfamily 3, group C, member 2
chr17_-_33760164 0.08 ENST00000445092.1
ENST00000394562.1
ENST00000447040.2
SLFN12
schlafen family member 12
chr1_+_67395922 0.08 ENST00000401042.3
ENST00000355356.3
MIER1
mesoderm induction early response 1, transcriptional regulator
chr2_+_223162866 0.07 ENST00000295226.1
CCDC140
coiled-coil domain containing 140
chr2_-_175870085 0.07 ENST00000409156.3
CHN1
chimerin 1
chr11_-_6624801 0.07 ENST00000534343.1
ENST00000254605.6
RRP8
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr10_+_99894380 0.07 ENST00000370584.3
R3HCC1L
R3H domain and coiled-coil containing 1-like
chr17_+_67410832 0.07 ENST00000590474.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr6_+_28092338 0.07 ENST00000340487.4
ZSCAN16
zinc finger and SCAN domain containing 16
chr9_+_99212403 0.07 ENST00000375251.3
ENST00000375249.4
HABP4
hyaluronan binding protein 4
chr17_-_10101868 0.07 ENST00000432992.2
ENST00000540214.1
GAS7
growth arrest-specific 7
chr17_-_44657017 0.07 ENST00000573185.1
ENST00000570550.1
ENST00000445552.2
ENST00000336125.5
ENST00000329240.4
ENST00000337845.7
ARL17A
ADP-ribosylation factor-like 17A
chr5_-_111091948 0.06 ENST00000447165.2
NREP
neuronal regeneration related protein
chr4_-_170897045 0.06 ENST00000508313.1
RP11-205M3.3
RP11-205M3.3
chr9_+_74526384 0.06 ENST00000334731.2
ENST00000377031.3
C9orf85
chromosome 9 open reading frame 85
chr5_+_125758865 0.06 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr14_-_64761078 0.06 ENST00000341099.4
ENST00000556275.1
ENST00000542956.1
ENST00000353772.3
ENST00000357782.2
ENST00000267525.6
ESR2
estrogen receptor 2 (ER beta)
chr9_+_100174344 0.06 ENST00000422139.2
TDRD7
tudor domain containing 7
chr11_+_125461607 0.06 ENST00000527606.1
STT3A
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr6_-_135818368 0.06 ENST00000367798.2
AHI1
Abelson helper integration site 1
chr12_-_71148357 0.06 ENST00000378778.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr2_+_54684327 0.06 ENST00000389980.3
SPTBN1
spectrin, beta, non-erythrocytic 1
chr10_+_97515409 0.06 ENST00000371207.3
ENST00000543964.1
ENTPD1
ectonucleoside triphosphate diphosphohydrolase 1
chr4_-_5890145 0.06 ENST00000397890.2
CRMP1
collapsin response mediator protein 1
chr3_-_62860704 0.06 ENST00000490353.2
CADPS
Ca++-dependent secretion activator
chr10_+_90672113 0.06 ENST00000371922.1
STAMBPL1
STAM binding protein-like 1
chr7_+_94536898 0.06 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr6_-_42418999 0.06 ENST00000340840.2
ENST00000354325.2
TRERF1
transcriptional regulating factor 1
chr1_+_24645915 0.06 ENST00000350501.5
GRHL3
grainyhead-like 3 (Drosophila)
chr5_+_125758813 0.06 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr19_-_42759300 0.06 ENST00000222329.4
ERF
Ets2 repressor factor
chr14_-_102829051 0.06 ENST00000536961.2
ENST00000541568.2
ENST00000216756.6
CINP
cyclin-dependent kinase 2 interacting protein
chr2_+_62423242 0.06 ENST00000301998.4
B3GNT2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
chrX_-_153141783 0.06 ENST00000458029.1
L1CAM
L1 cell adhesion molecule
chr16_+_25123148 0.06 ENST00000570981.1
LCMT1
leucine carboxyl methyltransferase 1
chr12_-_67197760 0.06 ENST00000539540.1
ENST00000540433.1
ENST00000541947.1
ENST00000538373.1
GRIP1
glutamate receptor interacting protein 1
chr10_+_24498060 0.06 ENST00000376454.3
ENST00000376452.3
KIAA1217
KIAA1217
chr1_+_222988406 0.06 ENST00000448808.1
ENST00000457636.1
ENST00000439440.1
RP11-452F19.3
RP11-452F19.3
chr17_+_63133587 0.05 ENST00000449996.3
ENST00000262406.9
RGS9
regulator of G-protein signaling 9
chr2_-_241759622 0.05 ENST00000320389.7
ENST00000498729.2
KIF1A
kinesin family member 1A
chr17_+_53343577 0.05 ENST00000573945.1
HLF
hepatic leukemia factor
chr12_-_31478428 0.05 ENST00000543615.1
FAM60A
family with sequence similarity 60, member A
chr16_+_25123041 0.05 ENST00000399069.3
ENST00000380966.4
LCMT1
leucine carboxyl methyltransferase 1
chr1_+_104198377 0.05 ENST00000370083.4
AMY1A
amylase, alpha 1A (salivary)
chr12_-_56221330 0.05 ENST00000546837.1
RP11-762I7.5
Uncharacterized protein
chr17_+_63133526 0.05 ENST00000443584.3
RGS9
regulator of G-protein signaling 9
chr17_-_32484313 0.05 ENST00000359872.6
ASIC2
acid-sensing (proton-gated) ion channel 2
chr1_-_154928562 0.05 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
chr14_-_71107921 0.05 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
CTD-2540L5.5
CTD-2540L5.6
chr3_+_167453026 0.05 ENST00000472941.1
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr2_-_167232484 0.05 ENST00000375387.4
ENST00000303354.6
ENST00000409672.1
SCN9A
sodium channel, voltage-gated, type IX, alpha subunit
chr8_-_11873043 0.05 ENST00000527396.1
RP11-481A20.11
Protein LOC101060662
chr10_+_24497704 0.05 ENST00000376456.4
ENST00000458595.1
KIAA1217
KIAA1217
chrX_-_153141434 0.05 ENST00000407935.2
ENST00000439496.1
L1CAM
L1 cell adhesion molecule
chr17_-_34257731 0.05 ENST00000431884.2
ENST00000425909.3
ENST00000394528.3
ENST00000430160.2
RDM1
RAD52 motif 1
chr17_-_40288449 0.05 ENST00000552162.1
ENST00000550504.1
RAB5C
RAB5C, member RAS oncogene family
chr5_-_114631958 0.05 ENST00000395557.4
CCDC112
coiled-coil domain containing 112
chr4_-_110223523 0.05 ENST00000399127.1
COL25A1
collagen, type XXV, alpha 1

Network of associatons between targets according to the STRING database.

First level regulatory network of SCRT1_SCRT2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 0.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.3 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.5 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 0.3 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.2 GO:0051585 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.7 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.2 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.7 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0 0.3 GO:0015755 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.1 GO:0061485 memory T cell proliferation(GO:0061485)
0.0 0.4 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.1 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.0 0.2 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.0 0.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.0 0.2 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.1 GO:0039020 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric nephron tubule development(GO:0039020) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.0 0.1 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.0 GO:0007623 circadian rhythm(GO:0007623)
0.0 0.4 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.2 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.0 0.6 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.1 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.0 0.0 GO:0050894 determination of affect(GO:0050894)
0.0 0.2 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.3 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.3 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.2 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.7 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.3 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.0 0.2 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.7 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 0.3 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.2 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.3 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.3 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.2 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.3 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.5 GO:0035198 miRNA binding(GO:0035198)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.0 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.0 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.0 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.2 GO:0016918 retinal binding(GO:0016918)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters