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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for RXRG

Z-value: 1.34

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Transcription factors associated with RXRG

Gene Symbol Gene ID Gene Info
ENSG00000143171.8 retinoid X receptor gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RXRGhg19_v2_chr1_-_165414414_165414433-0.108.5e-01Click!

Activity profile of RXRG motif

Sorted Z-values of RXRG motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_1174226 1.31 ENST00000587024.1
ENST00000361757.3
strawberry notch homolog 2 (Drosophila)
chr20_+_44637526 1.18 ENST00000372330.3
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr2_+_74212073 0.83 ENST00000441217.1
AC073046.25
chr5_+_149865377 0.82 ENST00000522491.1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr14_-_103989033 0.77 ENST00000553878.1
ENST00000557530.1
creatine kinase, brain
chr11_-_615942 0.76 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
interferon regulatory factor 7
chr11_-_65429891 0.72 ENST00000527874.1
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr19_+_50887585 0.69 ENST00000440232.2
ENST00000601098.1
ENST00000599857.1
ENST00000593887.1
polymerase (DNA directed), delta 1, catalytic subunit
chr16_+_30194916 0.69 ENST00000570045.1
ENST00000565497.1
ENST00000570244.1
coronin, actin binding protein, 1A
chr11_-_615570 0.68 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
interferon regulatory factor 7
chr19_-_49622348 0.68 ENST00000408991.2
chromosome 19 open reading frame 73
chr2_+_113763031 0.65 ENST00000259211.6
interleukin 36, alpha
chr17_+_7748233 0.62 ENST00000570632.1
lysine (K)-specific demethylase 6B
chr17_-_79304150 0.58 ENST00000574093.1
transmembrane protein 105
chr10_+_88718397 0.56 ENST00000372017.3
synuclein, gamma (breast cancer-specific protein 1)
chr14_-_35873856 0.56 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr3_-_49203744 0.55 ENST00000321895.6
coiled-coil domain containing 71
chr19_+_49622646 0.54 ENST00000334186.4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr21_-_45196326 0.53 ENST00000291568.5
cystatin B (stefin B)
chr6_+_31916733 0.53 ENST00000483004.1
complement factor B
chr6_+_30951487 0.52 ENST00000486149.2
ENST00000376296.3
mucin 21, cell surface associated
chr10_+_26986582 0.50 ENST00000376215.5
ENST00000376203.5
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr19_+_6361754 0.48 ENST00000597326.1
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr11_+_65383227 0.45 ENST00000355703.3
pecanex-like 3 (Drosophila)
chr14_-_24729251 0.45 ENST00000559136.1
transglutaminase 1
chr3_-_50340996 0.45 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
hyaluronoglucosaminidase 1
chr18_-_19748379 0.44 ENST00000579431.1
GATA6 antisense RNA 1 (head to head)
chr6_+_43737939 0.42 ENST00000372067.3
vascular endothelial growth factor A
chr19_+_18303992 0.42 ENST00000599612.2
MPV17 mitochondrial membrane protein-like 2
chr8_+_61822605 0.42 ENST00000526936.1
AC022182.1
chr11_+_45944190 0.41 ENST00000401752.1
ENST00000389968.3
ENST00000325468.5
ENST00000536139.1
glycosyltransferase-like 1B
chr19_+_41882466 0.41 ENST00000436170.2
transmembrane protein 91
chr13_+_114462193 0.40 ENST00000375353.3
transmembrane protein 255B
chr12_+_132413739 0.40 ENST00000443358.2
pseudouridylate synthase 1
chr9_-_140009130 0.40 ENST00000497375.1
ENST00000371579.2
dipeptidyl-peptidase 7
chr12_-_122241812 0.40 ENST00000538335.1
AC084018.1
chr9_-_131534188 0.39 ENST00000414921.1
zyg-11 related, cell cycle regulator
chr2_-_20101385 0.39 ENST00000431392.1
tetratricopeptide repeat domain 32
chr17_+_7211280 0.38 ENST00000419711.2
ENST00000571955.1
ENST00000573714.1
eukaryotic translation initiation factor 5A
chr22_-_29663954 0.38 ENST00000216085.7
rhomboid domain containing 3
chr22_-_18257178 0.38 ENST00000342111.5
BH3 interacting domain death agonist
chr19_+_532049 0.38 ENST00000606136.1
cell division cycle 34
chr8_-_145331153 0.38 ENST00000377412.4
KM-PA-2 protein; Uncharacterized protein
chr11_-_65430251 0.38 ENST00000534283.1
ENST00000527749.1
ENST00000533187.1
ENST00000525693.1
ENST00000534558.1
ENST00000532879.1
ENST00000532999.1
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr17_-_7120525 0.38 ENST00000447163.1
ENST00000399506.2
ENST00000302955.6
discs, large homolog 4 (Drosophila)
chr1_-_1850697 0.37 ENST00000378598.4
ENST00000416272.1
ENST00000310991.3
transmembrane protein 52
chr12_+_132413798 0.37 ENST00000440818.2
ENST00000542167.2
ENST00000538037.1
ENST00000456665.2
pseudouridylate synthase 1
chr8_-_11058847 0.37 ENST00000297303.4
ENST00000416569.2
XK, Kell blood group complex subunit-related family, member 6
chr15_-_43663214 0.37 ENST00000561661.1
zinc finger and SCAN domain containing 29
chr11_-_47447970 0.36 ENST00000298852.3
ENST00000530912.1
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr19_+_18530184 0.36 ENST00000601357.2
single stranded DNA binding protein 4
chr20_-_36793663 0.35 ENST00000536701.1
ENST00000536724.1
transglutaminase 2
chr14_+_103243813 0.35 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
TNF receptor-associated factor 3
chr16_+_2039946 0.35 ENST00000248121.2
ENST00000568896.1
synaptogyrin 3
chr19_-_39322497 0.35 ENST00000221418.4
enoyl CoA hydratase 1, peroxisomal
chr3_+_52454971 0.35 ENST00000465863.1
PHD finger protein 7
chr15_-_74494779 0.34 ENST00000571341.1
stimulated by retinoic acid 6
chr1_-_154946825 0.34 ENST00000368453.4
ENST00000368450.1
ENST00000366442.2
SHC (Src homology 2 domain containing) transforming protein 1
chr19_+_36239576 0.34 ENST00000587751.1
lin-37 homolog (C. elegans)
chr19_+_50354430 0.34 ENST00000599732.1
prostate tumor overexpressed 1
chr11_+_66624527 0.33 ENST00000393952.3
leucine rich repeat and fibronectin type III domain containing 4
chr17_-_2615031 0.33 ENST00000576885.1
ENST00000574426.2
clustered mitochondria (cluA/CLU1) homolog
chr11_+_64009072 0.32 ENST00000535135.1
ENST00000394540.3
FK506 binding protein 2, 13kDa
chr5_-_172755056 0.32 ENST00000520648.1
stanniocalcin 2
chr12_-_42631529 0.32 ENST00000548917.1
YY1 associated factor 2
chr5_+_139505520 0.32 ENST00000333305.3
IgA-inducing protein
chr22_-_32022280 0.32 ENST00000442379.1
phosphatidylserine decarboxylase
chr5_+_139493665 0.32 ENST00000331327.3
purine-rich element binding protein A
chr12_+_132413765 0.32 ENST00000376649.3
ENST00000322060.5
pseudouridylate synthase 1
chr17_-_73844722 0.32 ENST00000586257.1
WW domain binding protein 2
chr16_-_29466285 0.31 ENST00000330978.3
bolA family member 2
chr7_-_3083472 0.31 ENST00000356408.3
caspase recruitment domain family, member 11
chr19_+_54705025 0.31 ENST00000441429.1
ribosomal protein S9
chr7_+_2671663 0.31 ENST00000407643.1
tweety family member 3
chr19_+_6361795 0.31 ENST00000596149.1
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr19_+_17830051 0.31 ENST00000594625.1
ENST00000324096.4
ENST00000600186.1
ENST00000597735.1
microtubule-associated protein 1S
chr19_+_7968728 0.31 ENST00000397981.3
ENST00000545011.1
ENST00000397983.3
ENST00000397979.3
mitogen-activated protein kinase kinase 7
chr20_+_37230511 0.30 ENST00000373345.4
Rho GTPase activating protein 40
chr19_-_39322299 0.30 ENST00000601094.1
ENST00000595567.1
ENST00000602115.1
ENST00000601778.1
ENST00000597205.1
ENST00000595470.1
enoyl CoA hydratase 1, peroxisomal
chr1_-_154946792 0.30 ENST00000412170.1
SHC (Src homology 2 domain containing) transforming protein 1
chr19_+_50706866 0.30 ENST00000440075.2
ENST00000376970.2
ENST00000425460.1
ENST00000599920.1
ENST00000601313.1
myosin, heavy chain 14, non-muscle
chr22_+_30821784 0.30 ENST00000407550.3
mitochondrial fission process 1
chr19_-_4124079 0.29 ENST00000394867.4
ENST00000262948.5
mitogen-activated protein kinase kinase 2
chr16_-_29934558 0.29 ENST00000568995.1
ENST00000566413.1
potassium channel tetramerization domain containing 13
chr19_+_6361440 0.29 ENST00000245816.4
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr16_-_67700594 0.29 ENST00000602644.1
ENST00000243878.4
enkurin domain containing 1
chr7_+_766850 0.29 ENST00000437419.1
ENST00000440747.1
HEAT repeat containing 2
chr19_+_50353944 0.29 ENST00000594151.1
ENST00000600603.1
ENST00000601638.1
ENST00000221557.9
prostate tumor overexpressed 1
chr19_+_926000 0.29 ENST00000263620.3
AT rich interactive domain 3A (BRIGHT-like)
chr11_+_450255 0.29 ENST00000308020.5
phosphatidylserine synthase 2
chr3_+_122399697 0.29 ENST00000494811.1
poly (ADP-ribose) polymerase family, member 14
chr11_-_57089774 0.28 ENST00000527207.1
tankyrase 1 binding protein 1, 182kDa
chr17_-_79829190 0.28 ENST00000581876.1
ENST00000584461.1
ENST00000583868.1
ENST00000400721.4
ENST00000269321.7
Rho GDP dissociation inhibitor (GDI) alpha
chr17_+_38119216 0.28 ENST00000301659.4
gasdermin A
chr19_+_50919056 0.28 ENST00000599632.1
CTD-2545M3.6
chr11_-_45939374 0.28 ENST00000533151.1
ENST00000241041.3
peroxisomal biogenesis factor 16
chr20_-_36793774 0.28 ENST00000361475.2
transglutaminase 2
chr16_+_2933229 0.28 ENST00000573965.1
ENST00000572006.1
FLYWCH family member 2
chr1_-_6420737 0.28 ENST00000541130.1
ENST00000377845.3
acyl-CoA thioesterase 7
chr20_-_44539538 0.28 ENST00000372420.1
phospholipid transfer protein
chr22_-_20104700 0.27 ENST00000439169.2
ENST00000445045.1
ENST00000404751.3
ENST00000252136.7
ENST00000403707.3
tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr11_-_1587166 0.27 ENST00000331588.4
dual specificity phosphatase 8
chr7_-_766879 0.27 ENST00000537384.1
ENST00000417852.1
protein kinase, cAMP-dependent, regulatory, type I, beta
chr5_-_138730817 0.27 ENST00000434752.2
proline-rich basic protein 1
chr19_+_7587491 0.27 ENST00000264079.6
mucolipin 1
chr19_-_3772209 0.27 ENST00000555978.1
ENST00000555633.1
retina and anterior neural fold homeobox 2
chr7_-_767249 0.27 ENST00000403562.1
protein kinase, cAMP-dependent, regulatory, type I, beta
chr16_-_30582888 0.27 ENST00000563707.1
ENST00000567855.1
zinc finger protein 688
chr22_-_18257249 0.27 ENST00000399765.1
ENST00000399767.1
ENST00000399774.3
BH3 interacting domain death agonist
chr9_-_139334247 0.26 ENST00000371712.3
inositol polyphosphate-5-phosphatase, 72 kDa
chr1_+_1243947 0.26 ENST00000379031.5
pseudouridylate synthase-like 1
chr5_-_149829314 0.26 ENST00000407193.1
ribosomal protein S14
chr19_+_18451439 0.26 ENST00000597431.2
pyroglutamyl-peptidase I
chr19_-_7990991 0.26 ENST00000318978.4
cortexin 1
chr19_-_46148820 0.26 ENST00000587152.1
echinoderm microtubule associated protein like 2
chr9_-_131534160 0.26 ENST00000291900.2
zyg-11 related, cell cycle regulator
chr19_+_50354393 0.25 ENST00000391842.1
prostate tumor overexpressed 1
chr22_-_32058416 0.25 ENST00000439502.2
phosphatidylserine decarboxylase
chr19_+_3506261 0.25 ENST00000441788.2
fizzy/cell division cycle 20 related 1 (Drosophila)
chr6_+_43738444 0.25 ENST00000324450.6
ENST00000417285.2
ENST00000413642.3
ENST00000372055.4
ENST00000482630.2
ENST00000425836.2
ENST00000372064.4
ENST00000372077.4
ENST00000519767.1
vascular endothelial growth factor A
chr5_-_149829244 0.25 ENST00000312037.5
ribosomal protein S14
chr7_-_45960850 0.25 ENST00000381083.4
ENST00000381086.5
ENST00000275521.6
insulin-like growth factor binding protein 3
chr12_+_51633061 0.25 ENST00000551313.1
DAZ associated protein 2
chr17_+_9066252 0.25 ENST00000436734.1
netrin 1
chr9_-_139581848 0.25 ENST00000538402.1
ENST00000371694.3
1-acylglycerol-3-phosphate O-acyltransferase 2
chr6_+_2245982 0.25 ENST00000530346.1
ENST00000524770.1
ENST00000532124.1
ENST00000531092.1
ENST00000456943.2
ENST00000529893.1
GMDS antisense RNA 1 (head to head)
chr15_-_76352069 0.25 ENST00000305435.10
ENST00000563910.1
neuregulin 4
chr11_-_45939565 0.25 ENST00000525192.1
ENST00000378750.5
peroxisomal biogenesis factor 16
chr1_-_183538319 0.25 ENST00000420553.1
ENST00000419402.1
neutrophil cytosolic factor 2
chr17_+_47074758 0.25 ENST00000290341.3
insulin-like growth factor 2 mRNA binding protein 1
chr22_-_43567750 0.25 ENST00000494035.1
tubulin tyrosine ligase-like family, member 12
chr19_+_50354462 0.24 ENST00000601675.1
prostate tumor overexpressed 1
chr19_+_3136115 0.24 ENST00000262958.3
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
chr19_+_19496728 0.24 ENST00000537887.1
ENST00000417582.2
GATA zinc finger domain containing 2A
chr19_+_50180317 0.24 ENST00000534465.1
protein arginine methyltransferase 1
chr19_+_35630344 0.24 ENST00000455515.2
FXYD domain containing ion transport regulator 1
chr19_-_1021113 0.24 ENST00000333175.5
ENST00000356663.3
transmembrane protein 259
chr1_-_1009683 0.24 ENST00000453464.2
ring finger protein 223
chr2_+_95963052 0.24 ENST00000295225.5
Kv channel interacting protein 3, calsenilin
chr22_+_31489344 0.24 ENST00000404574.1
smoothelin
chr3_-_119379719 0.24 ENST00000493094.1
popeye domain containing 2
chr19_-_6279932 0.24 ENST00000252674.7
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr1_+_155146318 0.23 ENST00000368385.4
ENST00000545012.1
ENST00000392451.2
ENST00000368383.3
ENST00000368382.1
ENST00000334634.4
tripartite motif containing 46
chr11_+_63753883 0.23 ENST00000538426.1
ENST00000543004.1
OTU domain, ubiquitin aldehyde binding 1
chr19_-_13068012 0.23 ENST00000316939.1
growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr9_+_116638630 0.23 ENST00000452710.1
ENST00000374124.4
zinc finger protein 618
chr6_+_126112074 0.23 ENST00000453302.1
ENST00000417494.1
ENST00000229634.9
nuclear receptor coactivator 7
chr15_-_93965805 0.23 ENST00000556708.1
RP11-164C12.2
chr11_+_66036004 0.23 ENST00000311481.6
ENST00000527397.1
RAB1B, member RAS oncogene family
chr19_-_50432654 0.23 ENST00000596680.1
ENST00000594673.1
ENST00000597029.1
nucleoporin 62kDa
chr5_+_131593364 0.23 ENST00000253754.3
ENST00000379018.3
PDZ and LIM domain 4
chr16_-_11363178 0.23 ENST00000312693.3
transition protein 2 (during histone to protamine replacement)
chr16_+_30675654 0.23 ENST00000287468.5
ENST00000395073.2
fibrosin
chr22_+_19701985 0.23 ENST00000455784.2
ENST00000406395.1
septin 5
chr7_+_73242490 0.23 ENST00000431918.1
claudin 4
chr22_+_51176624 0.23 ENST00000216139.5
ENST00000529621.1
acrosin
chr12_-_54813229 0.22 ENST00000293379.4
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr19_+_35759824 0.22 ENST00000343550.5
upstream transcription factor 2, c-fos interacting
chr22_+_30821732 0.22 ENST00000355143.4
mitochondrial fission process 1
chr17_-_39928501 0.22 ENST00000420370.1
junction plakoglobin
chr19_-_14117074 0.22 ENST00000588885.1
ENST00000254325.4
regulatory factor X, 1 (influences HLA class II expression)
chr11_-_47447767 0.22 ENST00000530651.1
ENST00000524447.2
ENST00000531051.2
ENST00000526993.1
ENST00000602866.1
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr21_-_46962379 0.22 ENST00000311124.4
ENST00000380010.4
solute carrier family 19 (folate transporter), member 1
chr7_+_143078652 0.22 ENST00000354434.4
ENST00000449423.2
zyxin
chr2_-_220117867 0.22 ENST00000456818.1
ENST00000447205.1
tubulin, alpha 4a
chr17_+_33307503 0.22 ENST00000378526.4
ENST00000585941.1
ENST00000262327.5
ENST00000592690.1
ENST00000585740.1
ligase III, DNA, ATP-dependent
chr17_+_40811283 0.22 ENST00000251412.7
tubulin, gamma 2
chr19_+_54704990 0.22 ENST00000391753.2
ribosomal protein S9
chr11_-_64856497 0.22 ENST00000524632.1
ENST00000530719.1
transmembrane protein 262
chr22_-_41682172 0.22 ENST00000356244.3
Ran GTPase activating protein 1
chr17_-_7120498 0.21 ENST00000485100.1
discs, large homolog 4 (Drosophila)
chr12_+_6494285 0.21 ENST00000541102.1
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr17_+_2240916 0.21 ENST00000574563.1
small G protein signaling modulator 2
chr19_-_51504852 0.21 ENST00000391806.2
ENST00000347619.4
ENST00000291726.7
ENST00000320838.5
kallikrein-related peptidase 8
chr11_-_407103 0.21 ENST00000526395.1
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr2_+_74757050 0.21 ENST00000352222.3
ENST00000437202.1
HtrA serine peptidase 2
chr19_+_10362577 0.21 ENST00000592514.1
ENST00000307422.5
ENST00000253099.6
ENST00000590150.1
ENST00000590669.1
mitochondrial ribosomal protein L4
chr17_-_46688334 0.21 ENST00000239165.7
homeobox B7
chr8_+_117950422 0.21 ENST00000378279.3
alanine and arginine rich domain containing protein
chr3_-_48470838 0.21 ENST00000358459.4
ENST00000358536.4
plexin B1
chr22_-_32058166 0.21 ENST00000435900.1
ENST00000336566.4
phosphatidylserine decarboxylase
chr6_+_106535455 0.21 ENST00000424894.1
PR domain containing 1, with ZNF domain
chr5_-_176778523 0.21 ENST00000513877.1
ENST00000515209.1
ENST00000514458.1
ENST00000502560.1
lectin, mannose-binding 2
chr1_+_10534944 0.21 ENST00000356607.4
ENST00000538836.1
ENST00000491661.2
peroxisomal biogenesis factor 14
chr19_+_17186577 0.20 ENST00000595618.1
ENST00000594824.1
myosin IXB
chr19_+_52693259 0.20 ENST00000322088.6
ENST00000454220.2
ENST00000444322.2
ENST00000477989.1
protein phosphatase 2, regulatory subunit A, alpha
chr1_+_199996702 0.20 ENST00000367362.3
nuclear receptor subfamily 5, group A, member 2
chr17_+_39969183 0.20 ENST00000321562.4
FK506 binding protein 10, 65 kDa
chr14_-_78174344 0.20 ENST00000216489.3
alkB, alkylation repair homolog 1 (E. coli)
chr17_+_38498594 0.20 ENST00000394081.3
retinoic acid receptor, alpha
chr19_-_15560730 0.20 ENST00000389282.4
ENST00000263381.7
widely interspaced zinc finger motifs
chr19_+_54704718 0.20 ENST00000391752.1
ENST00000402367.1
ENST00000391751.3
ribosomal protein S9
chr17_-_39968406 0.20 ENST00000393928.1
leprecan-like 4
chr17_-_72889697 0.20 ENST00000310226.6
fatty acid desaturase 6
chr22_-_18256742 0.20 ENST00000317361.7
BH3 interacting domain death agonist
chr20_+_21686290 0.20 ENST00000398485.2
paired box 1
chr21_-_46237883 0.20 ENST00000397893.3
small ubiquitin-like modifier 3
chr22_+_18593446 0.20 ENST00000316027.6
tubulin, alpha 8
chr11_+_62439126 0.20 ENST00000377953.3
chromosome 11 open reading frame 83
chr7_+_44646218 0.20 ENST00000444676.1
ENST00000222673.5
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)

Network of associatons between targets according to the STRING database.

First level regulatory network of RXRG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.4 1.5 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.4 1.1 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.4 1.4 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.2 0.7 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.2 0.5 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.2 0.8 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.7 GO:0032796 uropod organization(GO:0032796)
0.1 1.2 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.1 0.6 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.5 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.1 0.7 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.5 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.1 0.7 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.3 GO:0042631 cellular response to water deprivation(GO:0042631)
0.1 0.6 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.4 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.1 0.4 GO:1900104 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 0.3 GO:1901899 positive regulation of relaxation of muscle(GO:1901079) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.1 0.2 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.1 0.5 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.1 0.5 GO:1903436 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.1 0.5 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 0.4 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.1 0.2 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.1 0.6 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.3 GO:0036116 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.4 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.1 0.2 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.1 0.2 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.1 0.2 GO:0002101 tRNA wobble cytosine modification(GO:0002101) RNA repair(GO:0042245)
0.1 0.4 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 0.3 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
0.1 0.2 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.1 0.5 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.3 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 0.8 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.3 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 0.2 GO:1901536 negative regulation of DNA demethylation(GO:1901536)
0.1 0.2 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.1 0.2 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.1 0.6 GO:0035897 proteolysis in other organism(GO:0035897)
0.1 0.2 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.2 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.1 0.6 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1 0.1 GO:0034204 lipid translocation(GO:0034204)
0.1 0.2 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.3 GO:0015692 lead ion transport(GO:0015692)
0.0 0.1 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.4 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.3 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.1 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.3 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.8 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210) embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.2 GO:0061056 sclerotome development(GO:0061056)
0.0 0.3 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.1 GO:1901207 regulation of heart looping(GO:1901207)
0.0 0.1 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.2 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:1902824 cleavage furrow ingression(GO:0036090) positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.4 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0033037 polysaccharide localization(GO:0033037)
0.0 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.0 0.2 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.4 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.1 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.0 0.3 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.1 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.0 0.1 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.2 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.1 GO:0071879 UDP-glucose catabolic process(GO:0006258) positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.4 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.2 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.2 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.1 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560) positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.0 0.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.1 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.1 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.0 0.1 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.0 0.2 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.0 0.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951) positive regulation of inclusion body assembly(GO:0090261)
0.0 0.1 GO:0071672 negative regulation of smooth muscle cell chemotaxis(GO:0071672)
0.0 0.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.2 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.4 GO:0043266 regulation of potassium ion transport(GO:0043266) regulation of potassium ion transmembrane transport(GO:1901379)
0.0 0.4 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.4 GO:0070970 interleukin-2 secretion(GO:0070970)
0.0 0.3 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.3 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.1 GO:0060581 ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581) regulation of neural retina development(GO:0061074) negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.2 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.2 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.5 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.5 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.0 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.0 0.1 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.0 0.2 GO:0099612 protein localization to axon(GO:0099612)
0.0 0.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.0 0.3 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.5 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:0033504 floor plate development(GO:0033504)
0.0 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.2 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.4 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.2 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.1 GO:0048148 behavioral response to cocaine(GO:0048148)
0.0 0.2 GO:1902915 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.1 GO:0048863 stem cell differentiation(GO:0048863)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.1 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.2 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.6 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.4 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.1 GO:0048619 hindgut morphogenesis(GO:0007442) embryonic hindgut morphogenesis(GO:0048619)
0.0 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.2 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.1 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.0 GO:0072343 pancreatic stellate cell proliferation(GO:0072343) response to metformin(GO:1901558) regulation of pancreatic stellate cell proliferation(GO:2000229) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.0 GO:0002086 diaphragm contraction(GO:0002086)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.2 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.0 GO:0033128 negative regulation of histone phosphorylation(GO:0033128)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.2 1.1 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.1 0.4 GO:0036117 hyaluranon cable(GO:0036117)
0.1 0.6 GO:0070435 Shc-EGFR complex(GO:0070435)
0.1 0.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.2 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.2 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.1 0.8 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.2 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.1 0.6 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 0.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.3 GO:0097513 myosin II filament(GO:0097513)
0.0 0.3 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.1 GO:0043257 laminin-8 complex(GO:0043257)
0.0 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.6 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.3 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.6 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.6 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.2 GO:0032010 phagolysosome(GO:0032010)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 1.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 1.6 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.4 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.6 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 0.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.2 1.8 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.6 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.5 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.1 0.8 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.7 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.8 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 0.7 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 1.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.3 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.1 0.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.2 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 0.6 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 0.6 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.4 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.7 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.2 GO:0070984 SET domain binding(GO:0070984)
0.1 0.2 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 0.2 GO:0004040 amidase activity(GO:0004040)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.2 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 0.2 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 0.2 GO:0008518 reduced folate carrier activity(GO:0008518)
0.1 0.6 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.3 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.2 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.1 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.7 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.2 GO:0043734 DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.4 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.3 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.1 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.0 0.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.2 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.3 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.6 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.3 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.1 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.6 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.9 GO:0005123 death receptor binding(GO:0005123)
0.0 0.3 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.0 GO:0052830 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.4 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.1 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.5 GO:0001848 complement binding(GO:0001848)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.0 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 3.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.0 GO:0047661 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.0 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.0 0.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.3 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.9 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.7 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.9 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.6 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 1.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.1 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.6 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.8 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.7 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.1 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.8 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.5 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes