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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for RXRA_NR2F6_NR2C2

Z-value: 1.32

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Transcription factors associated with RXRA_NR2F6_NR2C2

Gene Symbol Gene ID Gene Info
RXRA
ENSG00000186350.8 retinoid X receptor alpha
NR2F6
ENSG00000160113.5 nuclear receptor subfamily 2 group F member 6
NR2C2
ENSG00000177463.11 nuclear receptor subfamily 2 group C member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RXRAhg19_v2_chr9_+_137218362_1372184260.493.2e-01Click!
NR2C2hg19_v2_chr3_+_14989076_14989113-0.434.0e-01Click!
NR2F6hg19_v2_chr19_-_17356697_173567620.108.4e-01Click!

Activity profile of RXRA_NR2F6_NR2C2 motif

Sorted Z-values of RXRA_NR2F6_NR2C2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_39616410 1.08 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
PAK4
p21 protein (Cdc42/Rac)-activated kinase 4
chr17_+_37821593 1.00 ENST00000578283.1
TCAP
titin-cap
chr5_+_172484377 0.93 ENST00000523161.1
CREBRF
CREB3 regulatory factor
chr14_-_24729251 0.93 ENST00000559136.1
TGM1
transglutaminase 1
chr19_-_48867291 0.87 ENST00000435956.3
TMEM143
transmembrane protein 143
chr8_-_8639956 0.84 ENST00000522213.1
RP11-211C9.1
RP11-211C9.1
chr17_-_2615031 0.82 ENST00000576885.1
ENST00000574426.2
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr14_-_69350920 0.80 ENST00000553290.1
ACTN1
actinin, alpha 1
chr12_+_132413798 0.79 ENST00000440818.2
ENST00000542167.2
ENST00000538037.1
ENST00000456665.2
PUS1
pseudouridylate synthase 1
chr3_-_49203744 0.79 ENST00000321895.6
CCDC71
coiled-coil domain containing 71
chr22_+_30163340 0.78 ENST00000330029.6
ENST00000401406.3
UQCR10
ubiquinol-cytochrome c reductase, complex III subunit X
chr12_+_132413765 0.77 ENST00000376649.3
ENST00000322060.5
PUS1
pseudouridylate synthase 1
chr12_+_132413739 0.77 ENST00000443358.2
PUS1
pseudouridylate synthase 1
chr6_-_160148356 0.77 ENST00000401980.3
ENST00000545162.1
SOD2
superoxide dismutase 2, mitochondrial
chr11_-_61659006 0.77 ENST00000278829.2
FADS3
fatty acid desaturase 3
chr6_-_160147925 0.75 ENST00000535561.1
SOD2
superoxide dismutase 2, mitochondrial
chr3_-_119396193 0.74 ENST00000484810.1
ENST00000497116.1
ENST00000261070.2
COX17
COX17 cytochrome c oxidase copper chaperone
chr19_+_535835 0.71 ENST00000607527.1
ENST00000606065.1
CDC34
cell division cycle 34
chr6_+_31895467 0.71 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr11_-_61658853 0.71 ENST00000525588.1
ENST00000540820.1
FADS3
fatty acid desaturase 3
chr19_-_6720686 0.67 ENST00000245907.6
C3
complement component 3
chr1_+_161068179 0.66 ENST00000368011.4
ENST00000392192.2
KLHDC9
kelch domain containing 9
chr6_+_31895480 0.62 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2
CFB
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr19_-_42927251 0.62 ENST00000597001.1
LIPE
lipase, hormone-sensitive
chr19_+_45394477 0.62 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr17_+_73997419 0.60 ENST00000425876.2
CDK3
cyclin-dependent kinase 3
chr8_+_61822605 0.60 ENST00000526936.1
AC022182.1
AC022182.1
chr16_+_81272287 0.58 ENST00000425577.2
ENST00000564552.1
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr19_-_48867171 0.58 ENST00000377431.2
ENST00000436660.2
ENST00000541566.1
TMEM143
transmembrane protein 143
chr11_-_45939565 0.57 ENST00000525192.1
ENST00000378750.5
PEX16
peroxisomal biogenesis factor 16
chr16_+_2255841 0.55 ENST00000301725.7
MLST8
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr2_+_113763031 0.55 ENST00000259211.6
IL36A
interleukin 36, alpha
chr17_-_79817091 0.54 ENST00000570907.1
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr19_+_50919056 0.54 ENST00000599632.1
CTD-2545M3.6
CTD-2545M3.6
chr11_-_45939374 0.53 ENST00000533151.1
ENST00000241041.3
PEX16
peroxisomal biogenesis factor 16
chr16_+_2255710 0.52 ENST00000397124.1
ENST00000565250.1
MLST8
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr17_+_7533439 0.52 ENST00000441599.2
ENST00000380450.4
ENST00000416273.3
ENST00000575903.1
ENST00000576830.1
ENST00000571153.1
ENST00000575618.1
ENST00000576152.1
SHBG
sex hormone-binding globulin
chr19_-_7698599 0.51 ENST00000311069.5
PCP2
Purkinje cell protein 2
chr11_-_118868682 0.50 ENST00000526453.1
RP11-110I1.12
RP11-110I1.12
chr17_-_2614927 0.50 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr3_-_49314640 0.50 ENST00000436325.1
C3orf62
chromosome 3 open reading frame 62
chr22_-_20104700 0.49 ENST00000439169.2
ENST00000445045.1
ENST00000404751.3
ENST00000252136.7
ENST00000403707.3
TRMT2A
tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr19_-_10687983 0.49 ENST00000587069.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr8_+_145582633 0.48 ENST00000540505.1
SLC52A2
solute carrier family 52 (riboflavin transporter), member 2
chr16_-_4401258 0.48 ENST00000577031.1
PAM16
presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr11_+_66624527 0.44 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr17_-_2318731 0.44 ENST00000609667.1
AC006435.1
Uncharacterized protein
chr19_-_14201776 0.44 ENST00000269724.5
SAMD1
sterile alpha motif domain containing 1
chr11_-_66496655 0.43 ENST00000527010.1
SPTBN2
spectrin, beta, non-erythrocytic 2
chr2_+_27282134 0.42 ENST00000441931.1
AGBL5
ATP/GTP binding protein-like 5
chrX_-_1511617 0.42 ENST00000381401.5
SLC25A6
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr2_-_70475730 0.42 ENST00000445587.1
ENST00000433529.2
ENST00000415783.2
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr19_-_1021113 0.42 ENST00000333175.5
ENST00000356663.3
TMEM259
transmembrane protein 259
chr2_+_10442993 0.40 ENST00000423674.1
ENST00000307845.3
HPCAL1
hippocalcin-like 1
chr18_+_54318893 0.40 ENST00000593058.1
WDR7
WD repeat domain 7
chr19_+_49055332 0.40 ENST00000201586.2
SULT2B1
sulfotransferase family, cytosolic, 2B, member 1
chr1_+_44457441 0.39 ENST00000466180.1
CCDC24
coiled-coil domain containing 24
chr1_+_43855560 0.39 ENST00000562955.1
SZT2
seizure threshold 2 homolog (mouse)
chr2_-_85108240 0.39 ENST00000409133.1
TRABD2A
TraB domain containing 2A
chr17_+_46970134 0.38 ENST00000503641.1
ENST00000514808.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr15_+_91449971 0.38 ENST00000557865.1
MAN2A2
mannosidase, alpha, class 2A, member 2
chr12_+_113659234 0.38 ENST00000551096.1
ENST00000551099.1
ENST00000335509.6
ENST00000552897.1
ENST00000550785.1
ENST00000549279.1
TPCN1
two pore segment channel 1
chr17_-_4852332 0.38 ENST00000572383.1
PFN1
profilin 1
chr19_-_633576 0.38 ENST00000588649.2
POLRMT
polymerase (RNA) mitochondrial (DNA directed)
chr6_+_31916733 0.37 ENST00000483004.1
CFB
complement factor B
chr9_-_33402506 0.37 ENST00000377425.4
ENST00000537089.1
ENST00000297988.1
ENST00000539936.1
ENST00000541274.1
AQP7
aquaporin 7
chr5_+_1801503 0.37 ENST00000274137.5
ENST00000469176.1
NDUFS6
NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
chrY_-_1461617 0.36 ENSTR0000381401.5
SLC25A6
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr22_-_37415475 0.36 ENST00000403892.3
ENST00000249042.3
ENST00000438203.1
TST
thiosulfate sulfurtransferase (rhodanese)
chr15_+_43885799 0.35 ENST00000449946.1
ENST00000417289.1
CKMT1B
creatine kinase, mitochondrial 1B
chr19_-_51289436 0.35 ENST00000562076.1
CTD-2568A17.1
CTD-2568A17.1
chr17_-_73285293 0.35 ENST00000582778.1
ENST00000581988.1
ENST00000579207.1
ENST00000583332.1
ENST00000416858.2
ENST00000442286.2
ENST00000580151.1
ENST00000580994.1
ENST00000584438.1
ENST00000320362.3
ENST00000580273.1
SLC25A19
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr2_-_27603582 0.35 ENST00000323703.6
ENST00000436006.1
ZNF513
zinc finger protein 513
chr19_-_59023348 0.34 ENST00000601355.1
ENST00000263093.2
SLC27A5
solute carrier family 27 (fatty acid transporter), member 5
chr19_+_49109990 0.34 ENST00000321762.1
SPACA4
sperm acrosome associated 4
chrX_-_55020511 0.34 ENST00000375006.3
ENST00000374992.2
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr19_+_17420340 0.33 ENST00000359866.4
DDA1
DET1 and DDB1 associated 1
chr10_-_4285835 0.33 ENST00000454470.1
LINC00702
long intergenic non-protein coding RNA 702
chr16_+_30710462 0.33 ENST00000262518.4
ENST00000395059.2
ENST00000344771.4
SRCAP
Snf2-related CREBBP activator protein
chr11_+_86013253 0.33 ENST00000533986.1
ENST00000278483.3
C11orf73
chromosome 11 open reading frame 73
chr16_+_30076052 0.33 ENST00000563987.1
ALDOA
aldolase A, fructose-bisphosphate
chr7_-_139763521 0.32 ENST00000263549.3
PARP12
poly (ADP-ribose) polymerase family, member 12
chr19_-_2328572 0.32 ENST00000252622.10
LSM7
LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr19_+_11546153 0.32 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
PRKCSH
protein kinase C substrate 80K-H
chr19_-_10687948 0.32 ENST00000592285.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr19_+_11546440 0.31 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
PRKCSH
protein kinase C substrate 80K-H
chr5_+_179220979 0.31 ENST00000292596.10
ENST00000401985.3
LTC4S
leukotriene C4 synthase
chr5_-_176981417 0.31 ENST00000514747.1
ENST00000443375.2
ENST00000329540.5
FAM193B
family with sequence similarity 193, member B
chr1_-_6420737 0.31 ENST00000541130.1
ENST00000377845.3
ACOT7
acyl-CoA thioesterase 7
chr17_+_7531281 0.31 ENST00000575729.1
ENST00000340624.5
SHBG
sex hormone-binding globulin
chr8_-_80942061 0.31 ENST00000519386.1
MRPS28
mitochondrial ribosomal protein S28
chr16_+_30075783 0.30 ENST00000412304.2
ALDOA
aldolase A, fructose-bisphosphate
chr3_-_48936272 0.30 ENST00000544097.1
ENST00000430379.1
ENST00000319017.4
SLC25A20
solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
chr19_+_44100632 0.30 ENST00000533118.1
ZNF576
zinc finger protein 576
chr13_+_113344542 0.30 ENST00000487903.1
ENST00000375630.2
ENST00000375645.3
ENST00000283558.8
ATP11A
ATPase, class VI, type 11A
chr11_-_73687997 0.30 ENST00000545212.1
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr19_+_50887585 0.29 ENST00000440232.2
ENST00000601098.1
ENST00000599857.1
ENST00000593887.1
POLD1
polymerase (DNA directed), delta 1, catalytic subunit
chr1_-_43855444 0.29 ENST00000372455.4
MED8
mediator complex subunit 8
chr2_-_219134343 0.29 ENST00000447885.1
ENST00000420660.1
AAMP
angio-associated, migratory cell protein
chr12_+_10365082 0.29 ENST00000545859.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr2_+_74757050 0.29 ENST00000352222.3
ENST00000437202.1
HTRA2
HtrA serine peptidase 2
chr20_+_44486246 0.28 ENST00000255152.2
ENST00000454862.2
ZSWIM3
zinc finger, SWIM-type containing 3
chr19_+_36239576 0.28 ENST00000587751.1
LIN37
lin-37 homolog (C. elegans)
chr19_-_42192189 0.28 ENST00000401731.1
ENST00000338196.4
ENST00000006724.3
CEACAM7
carcinoembryonic antigen-related cell adhesion molecule 7
chr17_+_7123207 0.28 ENST00000584103.1
ENST00000579886.2
ACADVL
acyl-CoA dehydrogenase, very long chain
chr16_-_75284758 0.28 ENST00000561970.1
BCAR1
breast cancer anti-estrogen resistance 1
chr19_+_11546093 0.28 ENST00000591462.1
PRKCSH
protein kinase C substrate 80K-H
chr19_+_54606145 0.27 ENST00000485876.1
ENST00000391762.1
ENST00000471292.1
ENST00000391763.3
ENST00000391764.3
ENST00000303553.5
NDUFA3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
chr19_-_51530916 0.27 ENST00000594768.1
KLK11
kallikrein-related peptidase 11
chr8_+_96037205 0.27 ENST00000396124.4
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr1_-_154946825 0.27 ENST00000368453.4
ENST00000368450.1
ENST00000366442.2
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr16_+_30075595 0.27 ENST00000563060.2
ALDOA
aldolase A, fructose-bisphosphate
chr15_-_74501310 0.27 ENST00000423167.2
ENST00000432245.2
STRA6
stimulated by retinoic acid 6
chr19_-_1174226 0.27 ENST00000587024.1
ENST00000361757.3
SBNO2
strawberry notch homolog 2 (Drosophila)
chr14_-_101295407 0.27 ENST00000596284.1
AL117190.2
AL117190.2
chr9_-_35749162 0.27 ENST00000378094.4
ENST00000378103.3
GBA2
glucosidase, beta (bile acid) 2
chr18_+_54318566 0.27 ENST00000589935.1
ENST00000357574.3
WDR7
WD repeat domain 7
chr2_-_85108164 0.26 ENST00000409520.2
TRABD2A
TraB domain containing 2A
chr12_-_48276710 0.26 ENST00000550314.1
VDR
vitamin D (1,25- dihydroxyvitamin D3) receptor
chr1_-_151138422 0.26 ENST00000440902.2
LYSMD1
LysM, putative peptidoglycan-binding, domain containing 1
chr16_+_8736232 0.26 ENST00000562973.1
METTL22
methyltransferase like 22
chr2_-_28113217 0.26 ENST00000444339.2
RBKS
ribokinase
chr14_+_105331596 0.25 ENST00000556508.1
ENST00000414716.3
ENST00000453495.1
ENST00000418279.1
CEP170B
centrosomal protein 170B
chr11_-_66496430 0.25 ENST00000533211.1
SPTBN2
spectrin, beta, non-erythrocytic 2
chr15_-_74501360 0.25 ENST00000323940.5
STRA6
stimulated by retinoic acid 6
chr19_+_1205740 0.25 ENST00000326873.7
STK11
serine/threonine kinase 11
chr21_-_45196326 0.25 ENST00000291568.5
CSTB
cystatin B (stefin B)
chr15_+_45021183 0.25 ENST00000559390.1
TRIM69
tripartite motif containing 69
chr4_-_120243545 0.25 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr11_+_67798363 0.24 ENST00000525628.1
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr20_-_43883197 0.24 ENST00000338380.2
SLPI
secretory leukocyte peptidase inhibitor
chr4_+_79475019 0.24 ENST00000508214.1
ANXA3
annexin A3
chr17_+_7483761 0.24 ENST00000584180.1
CD68
CD68 molecule
chr8_-_80942139 0.24 ENST00000521434.1
ENST00000519120.1
ENST00000520946.1
MRPS28
mitochondrial ribosomal protein S28
chr8_-_73793975 0.24 ENST00000523881.1
RP11-1145L24.1
RP11-1145L24.1
chr16_-_69448 0.23 ENST00000326592.9
WASH4P
WAS protein family homolog 4 pseudogene
chr11_+_67798090 0.23 ENST00000313468.5
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr22_+_38453378 0.23 ENST00000437453.1
ENST00000356976.3
PICK1
protein interacting with PRKCA 1
chr3_+_37284824 0.23 ENST00000431105.1
GOLGA4
golgin A4
chr19_+_10196981 0.23 ENST00000591813.1
C19orf66
chromosome 19 open reading frame 66
chr14_-_91720224 0.23 ENST00000238699.3
ENST00000531499.2
GPR68
G protein-coupled receptor 68
chr11_+_67798114 0.23 ENST00000453471.2
ENST00000528492.1
ENST00000526339.1
ENST00000525419.1
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr17_-_4852243 0.23 ENST00000225655.5
PFN1
profilin 1
chr22_+_46663895 0.23 ENST00000421359.1
TTC38
tetratricopeptide repeat domain 38
chr17_+_73996987 0.23 ENST00000588812.1
ENST00000448471.1
CDK3
cyclin-dependent kinase 3
chr6_+_30524663 0.23 ENST00000376560.3
PRR3
proline rich 3
chr8_-_145652336 0.22 ENST00000529182.1
ENST00000526054.1
VPS28
vacuolar protein sorting 28 homolog (S. cerevisiae)
chr1_+_197881592 0.22 ENST00000367391.1
ENST00000367390.3
LHX9
LIM homeobox 9
chr11_-_65429891 0.22 ENST00000527874.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr4_-_103266355 0.22 ENST00000424970.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr11_+_64685026 0.22 ENST00000526559.1
PPP2R5B
protein phosphatase 2, regulatory subunit B', beta
chr18_+_54318616 0.22 ENST00000254442.3
WDR7
WD repeat domain 7
chr1_+_12079517 0.22 ENST00000235332.4
ENST00000436478.2
MIIP
migration and invasion inhibitory protein
chr6_+_116937636 0.22 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
RSPH4A
radial spoke head 4 homolog A (Chlamydomonas)
chr1_-_154946792 0.22 ENST00000412170.1
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr22_+_37415728 0.22 ENST00000404802.3
MPST
mercaptopyruvate sulfurtransferase
chr6_-_39693111 0.21 ENST00000373215.3
ENST00000538893.1
ENST00000287152.7
ENST00000373216.3
KIF6
kinesin family member 6
chr6_+_31926857 0.21 ENST00000375394.2
ENST00000544581.1
SKIV2L
superkiller viralicidic activity 2-like (S. cerevisiae)
chr21_-_43735446 0.21 ENST00000398431.2
TFF3
trefoil factor 3 (intestinal)
chr1_-_161039753 0.21 ENST00000368015.1
ARHGAP30
Rho GTPase activating protein 30
chr17_-_80023659 0.21 ENST00000578907.1
ENST00000577907.1
ENST00000578176.1
ENST00000582529.1
DUS1L
dihydrouridine synthase 1-like (S. cerevisiae)
chr17_+_17991197 0.21 ENST00000225729.3
DRG2
developmentally regulated GTP binding protein 2
chr2_-_70475701 0.21 ENST00000282574.4
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr22_+_37415676 0.21 ENST00000401419.3
MPST
mercaptopyruvate sulfurtransferase
chr19_+_49128209 0.21 ENST00000599748.1
ENST00000443164.1
ENST00000599029.1
SPHK2
sphingosine kinase 2
chr8_-_80942467 0.21 ENST00000518271.1
ENST00000276585.4
ENST00000521605.1
MRPS28
mitochondrial ribosomal protein S28
chr1_-_161102421 0.21 ENST00000490843.2
ENST00000368006.3
ENST00000392188.1
ENST00000545495.1
DEDD
death effector domain containing
chr11_+_65383227 0.21 ENST00000355703.3
PCNXL3
pecanex-like 3 (Drosophila)
chr20_-_36661826 0.21 ENST00000373448.2
ENST00000373447.3
TTI1
TELO2 interacting protein 1
chr7_-_1067968 0.20 ENST00000412051.1
C7orf50
chromosome 7 open reading frame 50
chr12_+_6493199 0.20 ENST00000228918.4
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr17_+_73629500 0.20 ENST00000375215.3
SMIM5
small integral membrane protein 5
chr1_+_228395755 0.20 ENST00000284548.11
ENST00000570156.2
ENST00000422127.1
ENST00000366707.4
ENST00000366709.4
OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr2_+_95963052 0.20 ENST00000295225.5
KCNIP3
Kv channel interacting protein 3, calsenilin
chr2_+_47799601 0.20 ENST00000601243.1
AC138655.1
CDNA: FLJ23120 fis, clone LNG07989; HCG1987724; Uncharacterized protein
chr1_-_16539094 0.19 ENST00000270747.3
ARHGEF19
Rho guanine nucleotide exchange factor (GEF) 19
chr20_-_44485835 0.19 ENST00000457981.1
ENST00000426915.1
ENST00000217455.4
ACOT8
acyl-CoA thioesterase 8
chr12_-_121972556 0.19 ENST00000545022.1
KDM2B
lysine (K)-specific demethylase 2B
chr17_-_7123021 0.19 ENST00000399510.2
DLG4
discs, large homolog 4 (Drosophila)
chr17_-_7531121 0.19 ENST00000573566.1
ENST00000269298.5
SAT2
spermidine/spermine N1-acetyltransferase family member 2
chr8_-_57123815 0.19 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr9_+_124103625 0.19 ENST00000594963.1
AL161784.1
Uncharacterized protein
chr19_-_38806390 0.19 ENST00000589247.1
ENST00000329420.8
ENST00000591784.1
YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr2_+_219135115 0.19 ENST00000248451.3
ENST00000273077.4
PNKD
paroxysmal nonkinesigenic dyskinesia
chr11_+_394196 0.19 ENST00000331563.2
ENST00000531857.1
PKP3
plakophilin 3
chr22_+_50354104 0.19 ENST00000360612.4
PIM3
pim-3 oncogene
chr16_+_88704978 0.19 ENST00000244241.4
IL17C
interleukin 17C
chr18_-_14970301 0.19 ENST00000580867.1
RP11-527H14.3
RP11-527H14.3
chr1_-_31381528 0.19 ENST00000339394.6
SDC3
syndecan 3
chr16_+_67927147 0.19 ENST00000291041.5
PSKH1
protein serine kinase H1
chr21_-_43735628 0.19 ENST00000291525.10
ENST00000518498.1
TFF3
trefoil factor 3 (intestinal)
chr2_+_27719697 0.19 ENST00000264717.2
ENST00000424318.2
GCKR
glucokinase (hexokinase 4) regulator
chr7_+_100210133 0.19 ENST00000393950.2
ENST00000424091.2
MOSPD3
motile sperm domain containing 3
chr11_-_65641044 0.18 ENST00000527378.1
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr19_+_45690646 0.18 ENST00000591569.1
AC006126.3
Uncharacterized protein
chr1_-_161039647 0.18 ENST00000368013.3
ARHGAP30
Rho GTPase activating protein 30
chr20_+_43374421 0.18 ENST00000372861.3
KCNK15
potassium channel, subfamily K, member 15
chr22_-_51021397 0.18 ENST00000406938.2
CHKB
choline kinase beta
chr6_+_106546808 0.18 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr1_+_151138500 0.18 ENST00000368905.4
SCNM1
sodium channel modifier 1

Network of associatons between targets according to the STRING database.

First level regulatory network of RXRA_NR2F6_NR2C2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.4 1.1 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.3 1.0 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.3 1.5 GO:0003068 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.3 0.8 GO:0052509 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.2 0.9 GO:0038161 prolactin signaling pathway(GO:0038161)
0.2 1.1 GO:0009439 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.2 0.7 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.2 0.7 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.1 0.4 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.1 0.9 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 0.6 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.4 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.5 GO:0032218 riboflavin transport(GO:0032218)
0.1 1.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.3 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1 0.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.3 GO:0038183 bile acid signaling pathway(GO:0038183)
0.1 0.5 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 0.8 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.3 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.3 GO:1902616 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.1 0.2 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1 0.2 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.2 GO:0050823 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.1 0.3 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.3 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 1.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.3 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 0.2 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 1.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.2 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.2 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.1 1.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.2 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 1.0 GO:0045023 G0 to G1 transition(GO:0045023)
0.1 0.2 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.7 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 0.5 GO:0034378 chylomicron assembly(GO:0034378)
0.1 0.4 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.2 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.1 0.3 GO:0019303 D-ribose catabolic process(GO:0019303)
0.1 0.7 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951) positive regulation of inclusion body assembly(GO:0090261)
0.0 0.2 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.3 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.3 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.6 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.0 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.0 0.4 GO:0015793 glycerol transport(GO:0015793)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.6 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.4 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.0 0.3 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.7 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.2 GO:1903939 regulation of TORC2 signaling(GO:1903939)
0.0 0.1 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.7 GO:0010155 regulation of proton transport(GO:0010155)
0.0 0.3 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.3 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.1 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.0 0.4 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.4 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.4 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.4 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0045726 regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726) male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.5 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998) cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0 0.3 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.8 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:1903299 regulation of glucokinase activity(GO:0033131) negative regulation of glucokinase activity(GO:0033132) regulation of hexokinase activity(GO:1903299) negative regulation of hexokinase activity(GO:1903300)
0.0 0.3 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.0 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.0 0.1 GO:0052361 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.9 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.3 GO:0038202 TORC1 signaling(GO:0038202)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:0046882 negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.2 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.2 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.2 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.1 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.1 GO:2001176 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.0 0.2 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.1 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.1 GO:0060032 notochord regression(GO:0060032)
0.0 0.2 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.1 GO:0030421 defecation(GO:0030421)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 1.3 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.2 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.3 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.0 GO:0097018 renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.1 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.3 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.1 GO:0090345 alkaloid catabolic process(GO:0009822) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.0 0.2 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.0 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.3 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0060992 response to fungicide(GO:0060992)
0.0 0.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.0 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.2 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.1 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0070543 response to linoleic acid(GO:0070543)
0.0 0.4 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0033594 response to hydroxyisoflavone(GO:0033594)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.1 0.5 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.6 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 1.4 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.7 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.2 GO:0036398 TCR signalosome(GO:0036398)
0.1 0.8 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.5 GO:0070435 Shc-EGFR complex(GO:0070435)
0.1 0.8 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.2 GO:0055087 Ski complex(GO:0055087)
0.1 0.4 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.8 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.1 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.7 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 1.0 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.4 GO:0031430 M band(GO:0031430)
0.0 0.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.7 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 2.7 GO:0072562 blood microparticle(GO:0072562)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.0 GO:0044393 microspike(GO:0044393)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.1 GO:0032010 phagolysosome(GO:0032010)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.9 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.2 0.6 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.2 1.0 GO:0051373 FATZ binding(GO:0051373)
0.2 0.8 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.2 0.8 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.2 0.4 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 0.7 GO:0016531 copper chaperone activity(GO:0016531)
0.1 1.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.8 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.5 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 1.0 GO:0005497 androgen binding(GO:0005497)
0.1 1.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.3 GO:0038181 bile acid receptor activity(GO:0038181)
0.1 0.9 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.4 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.1 0.3 GO:0015227 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226) acyl carnitine transmembrane transporter activity(GO:0015227)
0.1 0.4 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.3 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.1 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.4 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.2 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.1 0.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.5 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.3 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.2 GO:0004103 choline kinase activity(GO:0004103)
0.1 0.2 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.1 0.4 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.1 0.6 GO:0015288 porin activity(GO:0015288)
0.1 0.5 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.3 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.2 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 1.6 GO:0001848 complement binding(GO:0001848)
0.0 0.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.2 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 1.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.4 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.4 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.3 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.2 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.4 GO:0004386 helicase activity(GO:0004386)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.2 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.1 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.1 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.0 1.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.8 GO:0017166 vinculin binding(GO:0017166)
0.0 0.4 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.3 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.6 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.0 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.0 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 1.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.9 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.5 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.1 GO:0005124 scavenger receptor binding(GO:0005124)
0.0 0.1 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.0 GO:0036440 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.9 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.0 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.9 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.9 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.3 PID FOXO PATHWAY FoxO family signaling
0.0 0.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.9 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.8 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 3.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.5 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.6 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions