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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for RFX7_RFX4_RFX1

Z-value: 1.33

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Transcription factors associated with RFX7_RFX4_RFX1

Gene Symbol Gene ID Gene Info
RFX7
ENSG00000181827.10 regulatory factor X7
RFX4
ENSG00000111783.8 regulatory factor X4
RFX1
ENSG00000132005.4 regulatory factor X1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RFX7hg19_v2_chr15_-_56535464_565355210.758.6e-02Click!
RFX1hg19_v2_chr19_-_14117074_141171410.572.3e-01Click!
RFX4hg19_v2_chr12_+_106994905_106994954-0.098.6e-01Click!

Activity profile of RFX7_RFX4_RFX1 motif

Sorted Z-values of RFX7_RFX4_RFX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_51014460 2.56 ENST00000595669.1
JOSD2
Josephin domain containing 2
chr19_-_51014588 1.64 ENST00000598418.1
JOSD2
Josephin domain containing 2
chr19_+_55996565 1.07 ENST00000587400.1
NAT14
N-acetyltransferase 14 (GCN5-related, putative)
chr19_-_51014345 0.97 ENST00000391815.3
ENST00000594350.1
ENST00000601423.1
JOSD2
Josephin domain containing 2
chr16_+_24550857 0.76 ENST00000568015.1
RBBP6
retinoblastoma binding protein 6
chr19_-_50316517 0.74 ENST00000313777.4
ENST00000445575.2
FUZ
fuzzy planar cell polarity protein
chr19_-_50316489 0.71 ENST00000533418.1
FUZ
fuzzy planar cell polarity protein
chr7_-_105221898 0.69 ENST00000486180.1
ENST00000485614.1
ENST00000480514.1
EFCAB10
EF-hand calcium binding domain 10
chr13_+_103046954 0.67 ENST00000606448.1
FGF14-AS2
FGF14 antisense RNA 2
chr1_+_161068179 0.66 ENST00000368011.4
ENST00000392192.2
KLHDC9
kelch domain containing 9
chr19_+_507299 0.63 ENST00000359315.5
TPGS1
tubulin polyglutamylase complex subunit 1
chr1_-_85155939 0.55 ENST00000603677.1
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr19_-_50316423 0.54 ENST00000528094.1
ENST00000526575.1
FUZ
fuzzy planar cell polarity protein
chr1_+_32674675 0.54 ENST00000409358.1
DCDC2B
doublecortin domain containing 2B
chr12_+_119772502 0.52 ENST00000536742.1
ENST00000327554.2
CCDC60
coiled-coil domain containing 60
chr12_+_119772734 0.49 ENST00000539847.1
CCDC60
coiled-coil domain containing 60
chr1_-_86861660 0.45 ENST00000486215.1
ODF2L
outer dense fiber of sperm tails 2-like
chr19_-_40324767 0.44 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
DYRK1B
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr19_-_55791058 0.42 ENST00000587959.1
ENST00000585927.1
ENST00000587922.1
ENST00000585698.1
HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr4_-_2420335 0.41 ENST00000503000.1
ZFYVE28
zinc finger, FYVE domain containing 28
chr22_-_23484246 0.41 ENST00000216036.4
RTDR1
rhabdoid tumor deletion region gene 1
chr6_+_89790490 0.40 ENST00000336032.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr17_-_15244894 0.40 ENST00000338696.2
ENST00000543896.1
ENST00000539245.1
ENST00000539316.1
ENST00000395930.1
TEKT3
tektin 3
chr4_-_156297949 0.39 ENST00000515654.1
MAP9
microtubule-associated protein 9
chr11_+_61248583 0.39 ENST00000432063.2
ENST00000338608.2
PPP1R32
protein phosphatase 1, regulatory subunit 32
chr17_+_48585794 0.37 ENST00000576179.1
ENST00000419930.1
MYCBPAP
MYCBP associated protein
chr1_-_74663825 0.36 ENST00000370911.3
ENST00000370909.2
ENST00000354431.4
LRRIQ3
leucine-rich repeats and IQ motif containing 3
chrX_+_23925918 0.36 ENST00000379211.3
CXorf58
chromosome X open reading frame 58
chr12_-_121973974 0.36 ENST00000538379.1
ENST00000541318.1
ENST00000541511.1
KDM2B
lysine (K)-specific demethylase 2B
chr4_-_156298028 0.36 ENST00000433024.1
ENST00000379248.2
MAP9
microtubule-associated protein 9
chr19_-_41220957 0.34 ENST00000596357.1
ENST00000243583.6
ENST00000600080.1
ENST00000595254.1
ENST00000601967.1
ADCK4
aarF domain containing kinase 4
chr1_+_74663994 0.33 ENST00000472069.1
FPGT
fucose-1-phosphate guanylyltransferase
chr1_-_85156216 0.33 ENST00000342203.3
ENST00000370612.4
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr19_+_55996316 0.33 ENST00000205194.4
NAT14
N-acetyltransferase 14 (GCN5-related, putative)
chr9_+_26956371 0.33 ENST00000380062.5
ENST00000518614.1
IFT74
intraflagellar transport 74 homolog (Chlamydomonas)
chr7_+_12726474 0.33 ENST00000396662.1
ENST00000356797.3
ENST00000396664.2
ARL4A
ADP-ribosylation factor-like 4A
chr1_+_36549676 0.32 ENST00000207457.3
TEKT2
tektin 2 (testicular)
chr10_+_106113515 0.32 ENST00000369704.3
ENST00000312902.5
CCDC147
coiled-coil domain containing 147
chr14_+_89290965 0.32 ENST00000345383.5
ENST00000536576.1
ENST00000346301.4
ENST00000338104.6
ENST00000354441.6
ENST00000380656.2
ENST00000556651.1
ENST00000554686.1
TTC8
tetratricopeptide repeat domain 8
chr19_+_48972459 0.31 ENST00000427476.1
CYTH2
cytohesin 2
chr3_+_158449972 0.31 ENST00000486568.1
MFSD1
major facilitator superfamily domain containing 1
chr2_-_27851745 0.31 ENST00000394775.3
ENST00000522876.1
CCDC121
coiled-coil domain containing 121
chr16_-_29875057 0.31 ENST00000219789.6
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr20_-_44420507 0.31 ENST00000243938.4
WFDC3
WAP four-disulfide core domain 3
chr10_-_25304889 0.31 ENST00000483339.2
ENKUR
enkurin, TRPC channel interacting protein
chr14_+_52313833 0.31 ENST00000553560.1
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr1_-_85156090 0.31 ENST00000605755.1
ENST00000437941.2
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr1_+_43637996 0.30 ENST00000528956.1
ENST00000529956.1
WDR65
WD repeat domain 65
chr7_+_23637118 0.30 ENST00000448353.1
CCDC126
coiled-coil domain containing 126
chr10_+_15001430 0.30 ENST00000407572.1
MEIG1
meiosis/spermiogenesis associated 1
chr16_+_30773610 0.30 ENST00000566811.1
RNF40
ring finger protein 40, E3 ubiquitin protein ligase
chr19_-_40324255 0.29 ENST00000593685.1
ENST00000600611.1
DYRK1B
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr9_-_117267717 0.29 ENST00000374057.3
DFNB31
deafness, autosomal recessive 31
chr4_-_156298087 0.28 ENST00000311277.4
MAP9
microtubule-associated protein 9
chr1_+_6640046 0.28 ENST00000319084.5
ENST00000435905.1
ZBTB48
zinc finger and BTB domain containing 48
chr17_+_42977122 0.28 ENST00000412523.2
ENST00000331733.4
ENST00000417826.2
FAM187A
CCDC103
family with sequence similarity 187, member A
coiled-coil domain containing 103
chr12_-_76478386 0.27 ENST00000535020.2
NAP1L1
nucleosome assembly protein 1-like 1
chr19_+_5914213 0.27 ENST00000222125.5
ENST00000452990.2
ENST00000588865.1
CAPS
calcyphosine
chr6_+_89790459 0.27 ENST00000369472.1
PNRC1
proline-rich nuclear receptor coactivator 1
chr14_+_105452094 0.26 ENST00000551606.1
ENST00000547315.1
C14orf79
chromosome 14 open reading frame 79
chr18_-_32957260 0.26 ENST00000587422.1
ENST00000306346.1
ENST00000589332.1
ENST00000586687.1
ENST00000585522.1
ZNF396
zinc finger protein 396
chr10_+_70980051 0.26 ENST00000354624.5
ENST00000395086.2
HKDC1
hexokinase domain containing 1
chr5_-_54529415 0.26 ENST00000282572.4
CCNO
cyclin O
chr3_-_48659193 0.26 ENST00000330862.3
TMEM89
transmembrane protein 89
chr11_+_450255 0.26 ENST00000308020.5
PTDSS2
phosphatidylserine synthase 2
chr2_+_172778952 0.26 ENST00000392584.1
ENST00000264108.4
HAT1
histone acetyltransferase 1
chr17_+_29815113 0.26 ENST00000583755.1
RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr1_-_45140227 0.25 ENST00000372237.3
TMEM53
transmembrane protein 53
chr4_-_140005341 0.25 ENST00000379549.2
ENST00000512627.1
ELF2
E74-like factor 2 (ets domain transcription factor)
chr11_+_537494 0.24 ENST00000270115.7
LRRC56
leucine rich repeat containing 56
chr20_+_17550489 0.24 ENST00000246069.7
DSTN
destrin (actin depolymerizing factor)
chr17_+_2264983 0.24 ENST00000574650.1
SGSM2
small G protein signaling modulator 2
chrX_-_131623874 0.24 ENST00000436215.1
MBNL3
muscleblind-like splicing regulator 3
chr11_-_73882249 0.23 ENST00000535954.1
C2CD3
C2 calcium-dependent domain containing 3
chr5_-_149669612 0.23 ENST00000510347.1
CAMK2A
calcium/calmodulin-dependent protein kinase II alpha
chr2_-_63815628 0.23 ENST00000409562.3
WDPCP
WD repeat containing planar cell polarity effector
chr16_+_74411776 0.22 ENST00000429990.1
NPIPB15
nuclear pore complex interacting protein family, member B15
chr16_-_72127550 0.22 ENST00000268483.3
TXNL4B
thioredoxin-like 4B
chr14_+_96343100 0.22 ENST00000503525.2
LINC00617
long intergenic non-protein coding RNA 617
chr3_-_195076933 0.22 ENST00000423531.1
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr18_+_29671812 0.21 ENST00000261593.3
ENST00000578914.1
RNF138
ring finger protein 138, E3 ubiquitin protein ligase
chr17_-_65242063 0.21 ENST00000581159.1
HELZ
helicase with zinc finger
chr11_-_559377 0.20 ENST00000486629.1
C11orf35
chromosome 11 open reading frame 35
chr2_-_196933536 0.20 ENST00000312428.6
ENST00000410072.1
DNAH7
dynein, axonemal, heavy chain 7
chr11_-_108422926 0.20 ENST00000428840.1
ENST00000526312.1
EXPH5
exophilin 5
chr20_+_306177 0.20 ENST00000544632.1
SOX12
SRY (sex determining region Y)-box 12
chr19_-_11545920 0.19 ENST00000356392.4
ENST00000591179.1
CCDC151
coiled-coil domain containing 151
chr1_-_63988846 0.19 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
ITGB3BP
integrin beta 3 binding protein (beta3-endonexin)
chr16_-_71598823 0.19 ENST00000566202.1
ZNF19
zinc finger protein 19
chr3_+_132379154 0.19 ENST00000468022.1
ENST00000473651.1
ENST00000494238.2
UBA5
ubiquitin-like modifier activating enzyme 5
chr11_+_65779283 0.19 ENST00000312134.2
CST6
cystatin E/M
chr1_+_63989004 0.19 ENST00000371088.4
EFCAB7
EF-hand calcium binding domain 7
chr16_+_50059182 0.19 ENST00000562576.1
CNEP1R1
CTD nuclear envelope phosphatase 1 regulatory subunit 1
chr5_-_138739739 0.19 ENST00000514983.1
ENST00000507779.2
ENST00000451821.2
ENST00000450845.2
ENST00000509959.1
ENST00000302091.5
SPATA24
spermatogenesis associated 24
chr8_+_86999516 0.18 ENST00000521564.1
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr8_+_6566206 0.18 ENST00000518327.1
AGPAT5
1-acylglycerol-3-phosphate O-acyltransferase 5
chr5_-_133702761 0.18 ENST00000521118.1
ENST00000265334.4
ENST00000435211.1
CDKL3
cyclin-dependent kinase-like 3
chr1_-_51791596 0.18 ENST00000532836.1
ENST00000422925.1
TTC39A
tetratricopeptide repeat domain 39A
chr12_-_76478417 0.18 ENST00000552342.1
NAP1L1
nucleosome assembly protein 1-like 1
chr12_+_111051832 0.18 ENST00000550703.2
ENST00000551590.1
TCTN1
tectonic family member 1
chr17_+_48585958 0.18 ENST00000436259.2
MYCBPAP
MYCBP associated protein
chr11_+_71791693 0.18 ENST00000289488.2
ENST00000447974.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr5_+_110074685 0.18 ENST00000355943.3
ENST00000447245.2
SLC25A46
solute carrier family 25, member 46
chr4_-_140544386 0.18 ENST00000561977.1
RP11-308D13.3
RP11-308D13.3
chr12_-_76478446 0.18 ENST00000393263.3
ENST00000548044.1
ENST00000547704.1
ENST00000431879.3
ENST00000549596.1
ENST00000550934.1
ENST00000551600.1
ENST00000547479.1
ENST00000547773.1
ENST00000544816.1
ENST00000542344.1
ENST00000548273.1
NAP1L1
nucleosome assembly protein 1-like 1
chr8_+_15397732 0.18 ENST00000382020.4
ENST00000506802.1
ENST00000509380.1
ENST00000503731.1
TUSC3
tumor suppressor candidate 3
chr11_-_66104237 0.18 ENST00000530056.1
RIN1
Ras and Rab interactor 1
chr20_-_49575081 0.17 ENST00000371588.5
ENST00000371582.4
DPM1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr2_-_62081148 0.17 ENST00000404929.1
FAM161A
family with sequence similarity 161, member A
chr4_+_926171 0.17 ENST00000507319.1
ENST00000264771.4
TMEM175
transmembrane protein 175
chr9_-_130477912 0.17 ENST00000543175.1
PTRH1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr14_-_22005062 0.17 ENST00000317492.5
SALL2
spalt-like transcription factor 2
chr1_+_40627038 0.17 ENST00000372771.4
RLF
rearranged L-myc fusion
chr20_-_49575058 0.17 ENST00000371584.4
ENST00000371583.5
ENST00000413082.1
DPM1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr11_-_64885111 0.17 ENST00000528598.1
ENST00000310597.4
ZNHIT2
zinc finger, HIT-type containing 2
chr1_-_36915880 0.17 ENST00000445843.3
OSCP1
organic solute carrier partner 1
chr4_-_153457197 0.16 ENST00000281708.4
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr19_+_58111241 0.16 ENST00000597700.1
ENST00000332854.6
ENST00000597864.1
ZNF530
zinc finger protein 530
chr13_+_21141270 0.16 ENST00000319980.6
ENST00000537103.1
ENST00000389373.3
IFT88
intraflagellar transport 88 homolog (Chlamydomonas)
chr17_-_80656528 0.16 ENST00000538809.2
ENST00000269347.6
ENST00000571995.1
RAB40B
RAB40B, member RAS oncogene family
chr15_+_49913175 0.16 ENST00000403028.3
DTWD1
DTW domain containing 1
chr1_+_24120143 0.16 ENST00000374501.1
LYPLA2
lysophospholipase II
chr20_+_17550691 0.16 ENST00000474024.1
DSTN
destrin (actin depolymerizing factor)
chr3_-_10149907 0.16 ENST00000450660.2
ENST00000524279.1
FANCD2OS
FANCD2 opposite strand
chr6_+_112408768 0.16 ENST00000368656.2
ENST00000604268.1
FAM229B
family with sequence similarity 229, member B
chr2_-_62081254 0.16 ENST00000405894.3
FAM161A
family with sequence similarity 161, member A
chr19_+_41856816 0.16 ENST00000539627.1
TMEM91
transmembrane protein 91
chr20_+_18447771 0.16 ENST00000377603.4
POLR3F
polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
chr15_+_49913201 0.16 ENST00000329873.5
ENST00000558653.1
ENST00000559164.1
ENST00000560632.1
ENST00000559405.1
ENST00000251250.6
DTWD1
DTW domain containing 1
chr2_+_95537248 0.16 ENST00000427593.2
TEKT4
tektin 4
chr15_+_40531621 0.16 ENST00000560346.1
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr12_-_76478686 0.15 ENST00000261182.8
NAP1L1
nucleosome assembly protein 1-like 1
chr19_+_11546153 0.15 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
PRKCSH
protein kinase C substrate 80K-H
chr15_+_40531243 0.15 ENST00000558055.1
ENST00000455577.2
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr21_-_43916296 0.15 ENST00000398352.3
RSPH1
radial spoke head 1 homolog (Chlamydomonas)
chr2_-_192016276 0.15 ENST00000413064.1
STAT4
signal transducer and activator of transcription 4
chr6_+_134274322 0.15 ENST00000367871.1
ENST00000237264.4
TBPL1
TBP-like 1
chr19_+_50321528 0.15 ENST00000312865.6
ENST00000595185.1
ENST00000538643.1
MED25
mediator complex subunit 25
chr4_-_177116772 0.15 ENST00000280191.2
SPATA4
spermatogenesis associated 4
chr19_-_55791431 0.15 ENST00000593263.1
ENST00000376343.3
HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr1_-_1051455 0.15 ENST00000379339.1
ENST00000480643.1
ENST00000434641.1
ENST00000421241.2
C1orf159
chromosome 1 open reading frame 159
chr11_+_86748957 0.15 ENST00000526733.1
ENST00000532959.1
TMEM135
transmembrane protein 135
chrX_-_114252193 0.15 ENST00000243213.1
IL13RA2
interleukin 13 receptor, alpha 2
chr11_-_66103932 0.14 ENST00000311320.4
RIN1
Ras and Rab interactor 1
chr2_-_74648702 0.14 ENST00000518863.1
C2orf81
chromosome 2 open reading frame 81
chr21_-_47743719 0.14 ENST00000397680.1
ENST00000445935.1
ENST00000397685.4
ENST00000397682.3
ENST00000291691.7
C21orf58
chromosome 21 open reading frame 58
chr7_+_156902674 0.14 ENST00000594086.1
AC006967.1
Protein LOC100996426
chr8_-_144623595 0.14 ENST00000262577.5
ZC3H3
zinc finger CCCH-type containing 3
chr12_-_85430024 0.14 ENST00000547836.1
ENST00000532498.2
TSPAN19
tetraspanin 19
chr20_+_814349 0.14 ENST00000381941.3
FAM110A
family with sequence similarity 110, member A
chr19_+_14184370 0.14 ENST00000590772.1
hsa-mir-1199
hsa-mir-1199
chr19_-_51017881 0.14 ENST00000601207.1
ENST00000598657.1
ENST00000376916.3
ASPDH
aspartate dehydrogenase domain containing
chr20_+_306221 0.14 ENST00000342665.2
SOX12
SRY (sex determining region Y)-box 12
chr17_+_48585745 0.14 ENST00000323776.5
MYCBPAP
MYCBP associated protein
chr6_+_116937636 0.14 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
RSPH4A
radial spoke head 4 homolog A (Chlamydomonas)
chr15_-_49447771 0.14 ENST00000558843.1
ENST00000542928.1
ENST00000561248.1
COPS2
COP9 signalosome subunit 2
chr19_-_5293243 0.13 ENST00000591760.1
PTPRS
protein tyrosine phosphatase, receptor type, S
chr1_+_85527987 0.13 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WDR63
WD repeat domain 63
chr6_-_46620522 0.13 ENST00000275016.2
CYP39A1
cytochrome P450, family 39, subfamily A, polypeptide 1
chr10_-_82116497 0.13 ENST00000372204.3
DYDC1
DPY30 domain containing 1
chr18_+_61254221 0.13 ENST00000431153.1
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr17_+_78010428 0.13 ENST00000397545.4
ENST00000374877.3
ENST00000269318.5
ENST00000374876.4
ENST00000576033.1
ENST00000574099.1
CCDC40
coiled-coil domain containing 40
chr15_+_71184931 0.13 ENST00000560369.1
ENST00000260382.5
LRRC49
leucine rich repeat containing 49
chr22_-_33968239 0.13 ENST00000452586.2
ENST00000421768.1
LARGE
like-glycosyltransferase
chr19_+_5681153 0.13 ENST00000579559.1
ENST00000577222.1
HSD11B1L
RPL36
hydroxysteroid (11-beta) dehydrogenase 1-like
ribosomal protein L36
chr15_+_81489213 0.13 ENST00000559383.1
ENST00000394660.2
IL16
interleukin 16
chr6_-_80247140 0.13 ENST00000392959.1
ENST00000467898.3
LCA5
Leber congenital amaurosis 5
chr3_-_149510553 0.13 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ANKUB1
ankyrin repeat and ubiquitin domain containing 1
chr19_+_55888186 0.13 ENST00000291934.3
TMEM190
transmembrane protein 190
chr1_+_111888890 0.13 ENST00000369738.4
PIFO
primary cilia formation
chr22_-_39268192 0.13 ENST00000216083.6
CBX6
chromobox homolog 6
chr3_+_149689066 0.13 ENST00000593416.1
AC117395.1
LOC646903 protein; Uncharacterized protein
chr12_+_49297887 0.13 ENST00000266984.5
CCDC65
coiled-coil domain containing 65
chr3_-_47324079 0.13 ENST00000352910.4
KIF9
kinesin family member 9
chr3_-_45883558 0.13 ENST00000445698.1
ENST00000296135.6
LZTFL1
leucine zipper transcription factor-like 1
chr12_+_14927270 0.13 ENST00000544848.1
H2AFJ
H2A histone family, member J
chr5_+_176873789 0.12 ENST00000323249.3
ENST00000502922.1
PRR7
proline rich 7 (synaptic)
chr1_-_118727781 0.12 ENST00000336338.5
SPAG17
sperm associated antigen 17
chr1_-_1051736 0.12 ENST00000448924.1
ENST00000294576.5
ENST00000437760.1
ENST00000462097.1
ENST00000475119.1
C1orf159
chromosome 1 open reading frame 159
chr12_+_111051902 0.12 ENST00000397655.3
ENST00000471804.2
ENST00000377654.3
ENST00000397659.4
TCTN1
tectonic family member 1
chr8_+_38065104 0.12 ENST00000521311.1
BAG4
BCL2-associated athanogene 4
chr14_-_74025625 0.12 ENST00000553558.1
ENST00000563329.1
ENST00000334988.2
ENST00000560393.1
HEATR4
HEAT repeat containing 4
chr19_-_59084647 0.12 ENST00000594234.1
ENST00000596039.1
MZF1
myeloid zinc finger 1
chr12_-_108154705 0.12 ENST00000547188.1
PRDM4
PR domain containing 4
chr16_-_88923285 0.12 ENST00000542788.1
ENST00000569433.1
ENST00000268695.5
ENST00000568311.1
GALNS
galactosamine (N-acetyl)-6-sulfate sulfatase
chrX_-_131623982 0.12 ENST00000370844.1
MBNL3
muscleblind-like splicing regulator 3
chr6_+_52285131 0.12 ENST00000433625.2
EFHC1
EF-hand domain (C-terminal) containing 1
chr15_+_85923856 0.12 ENST00000560302.1
ENST00000394518.2
ENST00000361243.2
ENST00000560256.1
AKAP13
A kinase (PRKA) anchor protein 13
chr1_+_74663896 0.12 ENST00000370898.3
ENST00000467578.2
ENST00000370894.5
ENST00000482102.2
ENST00000609362.1
ENST00000534056.1
ENST00000557284.2
ENST00000370899.3
ENST00000370895.1
ENST00000534632.1
ENST00000370893.1
ENST00000370891.2
FPGT
FPGT-TNNI3K
TNNI3K
fucose-1-phosphate guanylyltransferase
FPGT-TNNI3K readthrough
TNNI3 interacting kinase
chr16_+_30772913 0.12 ENST00000563909.1
RNF40
ring finger protein 40, E3 ubiquitin protein ligase
chr4_+_26585538 0.12 ENST00000264866.4
TBC1D19
TBC1 domain family, member 19
chr19_+_35634146 0.11 ENST00000586063.1
ENST00000270310.2
ENST00000588265.1
FXYD7
FXYD domain containing ion transport regulator 7
chr19_+_11546440 0.11 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
PRKCSH
protein kinase C substrate 80K-H
chr7_+_2598628 0.11 ENST00000402050.2
ENST00000404984.1
ENST00000415271.2
ENST00000438376.2
IQCE
IQ motif containing E
chr19_+_16308711 0.11 ENST00000429941.2
ENST00000444449.2
ENST00000589822.1
AP1M1
adaptor-related protein complex 1, mu 1 subunit
chr16_+_78133536 0.11 ENST00000402655.2
ENST00000406884.2
ENST00000539474.2
ENST00000569818.1
ENST00000355860.3
ENST00000408984.3
WWOX
WW domain containing oxidoreductase
chr2_+_26785409 0.11 ENST00000329615.3
ENST00000409392.1
C2orf70
chromosome 2 open reading frame 70
chr1_-_207226313 0.11 ENST00000367084.1
YOD1
YOD1 deubiquitinase
chr14_+_61447832 0.11 ENST00000354886.2
ENST00000267488.4
SLC38A6
solute carrier family 38, member 6
chr15_+_71185148 0.11 ENST00000443425.2
ENST00000560755.1
LRRC49
leucine rich repeat containing 49

Network of associatons between targets according to the STRING database.

First level regulatory network of RFX7_RFX4_RFX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:2000314 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 0.4 GO:0080154 regulation of fertilization(GO:0080154)
0.1 0.4 GO:1903452 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.1 0.3 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.1 0.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.1 GO:0097192 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 0.7 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.2 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 0.1 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.1 0.7 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.4 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.7 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.1 0.2 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.5 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.3 GO:0050893 sensory processing(GO:0050893)
0.0 0.1 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.2 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.1 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.0 1.0 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.3 GO:0021997 neural plate axis specification(GO:0021997)
0.0 0.2 GO:2001176 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.6 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.2 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0031329 regulation of cellular catabolic process(GO:0031329)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.1 GO:0061433 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.0 0.2 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.2 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.1 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.0 GO:0010868 negative regulation of triglyceride biosynthetic process(GO:0010868)
0.0 0.2 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.3 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.4 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.2 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.2 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.0 0.6 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.3 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.2 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.0 0.5 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.3 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.0 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.0 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.2 GO:1902363 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.4 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.1 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.1 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.0 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.3 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.7 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.1 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.2 GO:0019336 phenol-containing compound catabolic process(GO:0019336) catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 0.0 GO:0090108 positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of pancreatic juice secretion(GO:0090187) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.0 0.2 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.0 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.0 GO:1900247 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.0 GO:0072344 rescue of stalled ribosome(GO:0072344)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.9 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.1 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.5 GO:0033503 HULC complex(GO:0033503)
0.0 0.0 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0034464 BBSome(GO:0034464)
0.0 1.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.2 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.5 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.0 GO:0005674 transcription factor TFIIF complex(GO:0005674)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 0.3 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.2 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.1 0.4 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 5.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.3 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.3 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.3 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.4 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.0 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.0 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.0 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.0 0.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.0 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0 1.5 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway