Project
NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for RELB
Z-value: 1.42
Motif logo
Transcription factors associated with RELB
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| RELB | hg19_v2_chr19_+_45504688_45504782 | 0.95 | 4.0e-03 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of RELB
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 9.8 | GO:0090023 | positive regulation of neutrophil chemotaxis(GO:0090023) |
| 1.8 | 5.4 | GO:0090291 | regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of osteoclast proliferation(GO:0090291) negative regulation of CD40 signaling pathway(GO:2000349) |
| 0.1 | 4.6 | GO:0050716 | positive regulation of interleukin-1 secretion(GO:0050716) |
| 0.7 | 3.5 | GO:0052027 | modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032) |
| 0.7 | 2.8 | GO:0002384 | hepatic immune response(GO:0002384) response to prolactin(GO:1990637) |
| 0.2 | 2.2 | GO:0070424 | regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) |
| 0.0 | 2.1 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.7 | 2.0 | GO:2000625 | regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627) |
| 0.1 | 1.8 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.3 | 1.4 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.6 | GO:0071682 | endocytic vesicle lumen(GO:0071682) |
| 0.6 | 2.8 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.0 | 2.1 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.3 | 2.0 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.2 | 1.8 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.0 | 1.8 | GO:0000145 | exocyst(GO:0000145) |
| 0.0 | 1.2 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.1 | 1.1 | GO:0070552 | BRISC complex(GO:0070552) |
| 0.2 | 1.0 | GO:0033257 | Bcl3/NF-kappaB2 complex(GO:0033257) |
| 0.1 | 1.0 | GO:0035631 | CD40 receptor complex(GO:0035631) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 8.7 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.3 | 5.4 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.1 | 4.6 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.1 | 3.5 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 0.3 | 2.8 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.1 | 2.7 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.1 | 2.0 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
| 0.5 | 1.4 | GO:0005146 | leukemia inhibitory factor receptor binding(GO:0005146) |
| 0.0 | 1.3 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.0 | 1.2 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 12.2 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.2 | 10.4 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.1 | 4.5 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.2 | 2.9 | ST STAT3 PATHWAY | STAT3 Pathway |
| 0.1 | 1.8 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.0 | 1.0 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.1 | 0.6 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
| 0.0 | 0.6 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.0 | 0.6 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 0.3 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 8.8 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.1 | 8.0 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.2 | 5.8 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.2 | 3.5 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.2 | 1.6 | REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX | Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex |
| 0.1 | 1.6 | REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
| 0.0 | 1.3 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.0 | 0.9 | REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 0.0 | 0.8 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.0 | 0.7 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |