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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for RARA

Z-value: 0.72

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Transcription factors associated with RARA

Gene Symbol Gene ID Gene Info
RARA
ENSG00000131759.13 retinoic acid receptor alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RARAhg19_v2_chr17_+_38498594_38498661-0.641.7e-01Click!

Activity profile of RARA motif

Sorted Z-values of RARA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_70963538 0.59 ENST00000413503.1
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr9_-_72374848 0.58 ENST00000377200.5
ENST00000340434.4
ENST00000472967.2
PTAR1
protein prenyltransferase alpha subunit repeat containing 1
chr6_+_151358048 0.51 ENST00000450635.1
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr14_+_38065052 0.43 ENST00000556845.1
TTC6
tetratricopeptide repeat domain 6
chrX_-_37706815 0.42 ENST00000378578.4
DYNLT3
dynein, light chain, Tctex-type 3
chr14_-_54955376 0.39 ENST00000553333.1
GMFB
glia maturation factor, beta
chr5_-_136649218 0.39 ENST00000510405.1
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr5_-_114961858 0.36 ENST00000282382.4
ENST00000456936.3
ENST00000408996.4
TMED7-TICAM2
TMED7
TICAM2
TMED7-TICAM2 readthrough
transmembrane emp24 protein transport domain containing 7
toll-like receptor adaptor molecule 2
chr2_+_189157536 0.35 ENST00000409580.1
ENST00000409637.3
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr2_+_189157498 0.33 ENST00000359135.3
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr1_+_222988363 0.32 ENST00000450784.1
ENST00000426045.1
ENST00000457955.1
ENST00000444858.1
ENST00000435378.1
ENST00000441676.1
RP11-452F19.3
RP11-452F19.3
chr22_-_29138386 0.32 ENST00000544772.1
CHEK2
checkpoint kinase 2
chr8_-_101348408 0.32 ENST00000519527.1
ENST00000522369.1
RNF19A
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr14_+_22600515 0.31 ENST00000390456.3
TRAV8-7
T cell receptor alpha variable 8-7 (non-functional)
chr17_-_26926005 0.31 ENST00000536674.2
SPAG5
sperm associated antigen 5
chr13_+_43597269 0.30 ENST00000379221.2
DNAJC15
DnaJ (Hsp40) homolog, subfamily C, member 15
chr14_+_54976603 0.30 ENST00000557317.1
CGRRF1
cell growth regulator with ring finger domain 1
chr15_+_23255242 0.28 ENST00000450802.3
GOLGA8I
golgin A8 family, member I
chr7_+_130794878 0.27 ENST00000416992.2
MKLN1
muskelin 1, intracellular mediator containing kelch motifs
chr3_-_101232019 0.27 ENST00000394095.2
ENST00000394091.1
ENST00000394094.2
ENST00000358203.3
ENST00000348610.3
ENST00000314261.7
SENP7
SUMO1/sentrin specific peptidase 7
chr4_-_10459009 0.26 ENST00000507515.1
ZNF518B
zinc finger protein 518B
chr11_-_18610214 0.26 ENST00000300038.7
ENST00000396197.3
ENST00000320750.6
UEVLD
UEV and lactate/malate dehyrogenase domains
chr6_+_54711533 0.26 ENST00000306858.7
FAM83B
family with sequence similarity 83, member B
chr2_-_113191096 0.25 ENST00000496537.1
ENST00000330575.5
ENST00000302558.3
RGPD8
RANBP2-like and GRIP domain containing 8
chr7_+_97910962 0.24 ENST00000539286.1
BRI3
brain protein I3
chr17_-_4463856 0.24 ENST00000574584.1
ENST00000381550.3
ENST00000301395.3
GGT6
gamma-glutamyltransferase 6
chr9_+_114393581 0.24 ENST00000313525.3
DNAJC25
DnaJ (Hsp40) homolog, subfamily C , member 25
chr1_+_225965518 0.24 ENST00000304786.7
ENST00000366839.4
ENST00000366838.1
SRP9
signal recognition particle 9kDa
chr6_-_146285221 0.24 ENST00000367503.3
ENST00000438092.2
ENST00000275233.7
SHPRH
SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
chr6_+_96025341 0.24 ENST00000369293.1
ENST00000358812.4
MANEA
mannosidase, endo-alpha
chrX_+_51486481 0.24 ENST00000340438.4
GSPT2
G1 to S phase transition 2
chr9_-_21995249 0.23 ENST00000494262.1
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr12_+_102091400 0.23 ENST00000229266.3
ENST00000549872.1
CHPT1
choline phosphotransferase 1
chr9_+_86595626 0.23 ENST00000445877.1
ENST00000325875.3
RMI1
RecQ mediated genome instability 1
chr3_-_50360165 0.22 ENST00000428028.1
HYAL2
hyaluronoglucosaminidase 2
chr2_-_40006357 0.22 ENST00000505747.1
THUMPD2
THUMP domain containing 2
chr11_-_2906979 0.22 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
CDKN1C
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr10_-_126849626 0.21 ENST00000530884.1
CTBP2
C-terminal binding protein 2
chr3_+_43732362 0.21 ENST00000458276.2
ABHD5
abhydrolase domain containing 5
chr13_+_103451399 0.21 ENST00000257336.1
ENST00000448849.2
BIVM
basic, immunoglobulin-like variable motif containing
chr4_+_38665810 0.21 ENST00000261438.5
ENST00000514033.1
KLF3
Kruppel-like factor 3 (basic)
chr1_+_220921582 0.21 ENST00000359316.2
MARC2
mitochondrial amidoxime reducing component 2
chr12_+_67663056 0.20 ENST00000545606.1
CAND1
cullin-associated and neddylation-dissociated 1
chr14_-_45603657 0.20 ENST00000396062.3
FKBP3
FK506 binding protein 3, 25kDa
chr15_+_76135622 0.20 ENST00000338677.4
ENST00000267938.4
ENST00000569423.1
UBE2Q2
ubiquitin-conjugating enzyme E2Q family member 2
chr13_-_52026730 0.20 ENST00000420668.2
INTS6
integrator complex subunit 6
chr9_+_114393634 0.20 ENST00000556107.1
ENST00000374294.3
DNAJC25
DNAJC25-GNG10
DnaJ (Hsp40) homolog, subfamily C , member 25
DNAJC25-GNG10 readthrough
chr12_-_44152551 0.20 ENST00000416848.2
ENST00000550784.1
ENST00000547156.1
ENST00000549868.1
ENST00000553166.1
ENST00000551923.1
ENST00000431332.3
ENST00000344862.5
PUS7L
pseudouridylate synthase 7 homolog (S. cerevisiae)-like
chr8_+_67344710 0.20 ENST00000379385.4
ENST00000396623.3
ENST00000415254.1
ADHFE1
alcohol dehydrogenase, iron containing, 1
chr7_-_105752971 0.20 ENST00000011473.2
SYPL1
synaptophysin-like 1
chr14_+_101295948 0.19 ENST00000452514.2
MEG3
maternally expressed 3 (non-protein coding)
chr5_+_63461642 0.19 ENST00000296615.6
ENST00000381081.2
ENST00000389100.4
RNF180
ring finger protein 180
chr10_+_115438920 0.19 ENST00000429617.1
ENST00000369331.4
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr2_-_175351744 0.19 ENST00000295500.4
ENST00000392552.2
ENST00000392551.2
GPR155
G protein-coupled receptor 155
chr4_-_87855851 0.19 ENST00000473559.1
C4orf36
chromosome 4 open reading frame 36
chr4_-_76439483 0.19 ENST00000380840.2
ENST00000513257.1
ENST00000507014.1
RCHY1
ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chr4_+_184580420 0.19 ENST00000334690.6
ENST00000357207.4
TRAPPC11
trafficking protein particle complex 11
chr1_-_93426998 0.18 ENST00000370310.4
FAM69A
family with sequence similarity 69, member A
chr1_-_222763240 0.18 ENST00000352967.4
ENST00000391882.1
ENST00000543857.1
TAF1A
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
chr7_+_30068260 0.18 ENST00000440706.2
PLEKHA8
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
chr1_+_219347203 0.18 ENST00000366927.3
LYPLAL1
lysophospholipase-like 1
chr5_+_59783540 0.18 ENST00000515734.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr1_-_85156417 0.18 ENST00000422026.1
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr7_-_21985656 0.18 ENST00000406877.3
CDCA7L
cell division cycle associated 7-like
chr1_-_152061537 0.17 ENST00000368806.1
TCHHL1
trichohyalin-like 1
chr1_-_16939976 0.17 ENST00000430580.2
NBPF1
neuroblastoma breakpoint family, member 1
chr4_-_184580304 0.17 ENST00000510968.1
ENST00000512740.1
ENST00000327570.9
RWDD4
RWD domain containing 4
chr1_-_211848899 0.17 ENST00000366998.3
ENST00000540251.1
ENST00000366999.4
NEK2
NIMA-related kinase 2
chr14_-_71107921 0.17 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
CTD-2540L5.5
CTD-2540L5.6
chr1_+_29241027 0.17 ENST00000373797.1
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr5_+_118690466 0.17 ENST00000503646.1
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr10_+_62538248 0.17 ENST00000448257.2
CDK1
cyclin-dependent kinase 1
chr1_+_160709055 0.16 ENST00000368043.3
ENST00000368042.3
ENST00000458602.2
ENST00000458104.2
SLAMF7
SLAM family member 7
chr6_-_110500826 0.16 ENST00000265601.3
ENST00000447287.1
ENST00000444391.1
WASF1
WAS protein family, member 1
chr1_+_76251912 0.16 ENST00000370826.3
RABGGTB
Rab geranylgeranyltransferase, beta subunit
chr13_+_53030107 0.16 ENST00000490903.1
ENST00000480747.1
CKAP2
cytoskeleton associated protein 2
chr10_+_60144782 0.16 ENST00000487519.1
TFAM
transcription factor A, mitochondrial
chr11_+_114310237 0.16 ENST00000539119.1
REXO2
RNA exonuclease 2
chr9_-_125027079 0.16 ENST00000417201.3
RBM18
RNA binding motif protein 18
chr4_-_159592996 0.16 ENST00000508457.1
C4orf46
chromosome 4 open reading frame 46
chr13_+_53029564 0.16 ENST00000468284.1
ENST00000378034.3
ENST00000258607.5
ENST00000378037.5
CKAP2
cytoskeleton associated protein 2
chr10_+_60145155 0.15 ENST00000373895.3
TFAM
transcription factor A, mitochondrial
chr19_-_40030861 0.15 ENST00000390658.2
EID2
EP300 interacting inhibitor of differentiation 2
chr12_-_56848426 0.15 ENST00000257979.4
MIP
major intrinsic protein of lens fiber
chr11_-_130184470 0.15 ENST00000357899.4
ENST00000397753.1
ZBTB44
zinc finger and BTB domain containing 44
chr7_-_100239132 0.15 ENST00000223051.3
ENST00000431692.1
TFR2
transferrin receptor 2
chr18_+_12947981 0.15 ENST00000262124.11
SEH1L
SEH1-like (S. cerevisiae)
chr6_+_12008986 0.15 ENST00000491710.1
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr1_-_59165763 0.15 ENST00000472487.1
MYSM1
Myb-like, SWIRM and MPN domains 1
chr5_+_112312454 0.15 ENST00000543319.1
DCP2
decapping mRNA 2
chr3_-_88108192 0.15 ENST00000309534.6
CGGBP1
CGG triplet repeat binding protein 1
chr13_+_25670268 0.15 ENST00000281589.3
PABPC3
poly(A) binding protein, cytoplasmic 3
chr16_+_31885079 0.15 ENST00000300870.10
ENST00000394846.3
ZNF267
zinc finger protein 267
chr5_+_112312399 0.15 ENST00000515408.1
ENST00000513585.1
DCP2
decapping mRNA 2
chr11_-_8986279 0.15 ENST00000534025.1
TMEM9B
TMEM9 domain family, member B
chr7_-_30544405 0.15 ENST00000409390.1
ENST00000409144.1
ENST00000005374.6
ENST00000409436.1
ENST00000275428.4
GGCT
gamma-glutamylcyclotransferase
chr6_-_146285455 0.14 ENST00000367505.2
SHPRH
SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
chr7_-_105752651 0.14 ENST00000470347.1
ENST00000455385.2
SYPL1
synaptophysin-like 1
chr2_+_171673072 0.14 ENST00000358196.3
ENST00000375272.1
GAD1
glutamate decarboxylase 1 (brain, 67kDa)
chr13_+_73356197 0.14 ENST00000326291.6
PIBF1
progesterone immunomodulatory binding factor 1
chr19_+_44331555 0.14 ENST00000590950.1
ZNF283
zinc finger protein 283
chr15_-_66790146 0.14 ENST00000316634.5
SNAPC5
small nuclear RNA activating complex, polypeptide 5, 19kDa
chr11_-_102323489 0.14 ENST00000361236.3
TMEM123
transmembrane protein 123
chr5_+_131892815 0.14 ENST00000453394.1
RAD50
RAD50 homolog (S. cerevisiae)
chr12_+_22778116 0.14 ENST00000538218.1
ETNK1
ethanolamine kinase 1
chr1_-_40367668 0.14 ENST00000397332.2
ENST00000429311.1
MYCL
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr2_-_86790472 0.14 ENST00000409727.1
CHMP3
charged multivesicular body protein 3
chr11_-_12030681 0.14 ENST00000529338.1
DKK3
dickkopf WNT signaling pathway inhibitor 3
chr1_+_222988406 0.14 ENST00000448808.1
ENST00000457636.1
ENST00000439440.1
RP11-452F19.3
RP11-452F19.3
chr5_-_171433548 0.14 ENST00000517395.1
FBXW11
F-box and WD repeat domain containing 11
chr11_+_58910201 0.14 ENST00000528737.1
FAM111A
family with sequence similarity 111, member A
chr15_+_22736484 0.14 ENST00000560659.2
GOLGA6L1
golgin A6 family-like 1
chr16_-_88752889 0.14 ENST00000332281.5
SNAI3
snail family zinc finger 3
chr2_-_208030886 0.13 ENST00000426163.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr19_+_11877838 0.13 ENST00000357901.4
ENST00000454339.2
ZNF441
zinc finger protein 441
chr16_-_14724131 0.13 ENST00000341484.7
PARN
poly(A)-specific ribonuclease
chr2_+_157291953 0.13 ENST00000310454.6
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr11_-_18610246 0.13 ENST00000379387.4
ENST00000541984.1
UEVLD
UEV and lactate/malate dehyrogenase domains
chr5_-_114961673 0.13 ENST00000333314.3
TMED7-TICAM2
TMED7-TICAM2 readthrough
chr1_+_109289279 0.13 ENST00000370008.3
STXBP3
syntaxin binding protein 3
chr16_+_68573640 0.13 ENST00000398253.2
ENST00000573161.1
ZFP90
ZFP90 zinc finger protein
chr9_-_135230336 0.13 ENST00000224140.5
ENST00000372169.2
ENST00000393220.1
SETX
senataxin
chr11_+_1856034 0.13 ENST00000341958.3
SYT8
synaptotagmin VIII
chr6_-_57086200 0.13 ENST00000468148.1
RAB23
RAB23, member RAS oncogene family
chr11_+_105948216 0.13 ENST00000278618.4
AASDHPPT
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr6_+_31540056 0.13 ENST00000418386.2
LTA
lymphotoxin alpha
chr10_+_23728198 0.13 ENST00000376495.3
OTUD1
OTU domain containing 1
chr13_-_48575401 0.13 ENST00000433022.1
ENST00000544100.1
SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chr6_-_134861089 0.13 ENST00000606039.1
RP11-557H15.4
RP11-557H15.4
chr18_-_812517 0.12 ENST00000584307.1
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr1_-_200379180 0.12 ENST00000294740.3
ZNF281
zinc finger protein 281
chr5_-_55290773 0.12 ENST00000502326.3
ENST00000381298.2
IL6ST
interleukin 6 signal transducer (gp130, oncostatin M receptor)
chr1_-_33168336 0.12 ENST00000373484.3
SYNC
syncoilin, intermediate filament protein
chr19_+_5904866 0.12 ENST00000339485.3
VMAC
vimentin-type intermediate filament associated coiled-coil protein
chr2_-_122407007 0.12 ENST00000263710.4
ENST00000455322.2
ENST00000397587.3
ENST00000541377.1
CLASP1
cytoplasmic linker associated protein 1
chr9_+_139873264 0.12 ENST00000446677.1
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr22_-_29137771 0.12 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
CHEK2
checkpoint kinase 2
chr3_+_44596679 0.12 ENST00000426540.1
ENST00000431636.1
ENST00000341840.3
ENST00000273320.3
ZKSCAN7
zinc finger with KRAB and SCAN domains 7
chr7_-_16460863 0.12 ENST00000407010.2
ENST00000399310.3
ISPD
isoprenoid synthase domain containing
chr21_-_34144157 0.12 ENST00000331923.4
PAXBP1
PAX3 and PAX7 binding protein 1
chr4_+_76439665 0.12 ENST00000508105.1
ENST00000311638.3
ENST00000380837.3
ENST00000507556.1
ENST00000504190.1
ENST00000507885.1
ENST00000502620.1
ENST00000514480.1
THAP6
THAP domain containing 6
chr5_+_170288856 0.12 ENST00000523189.1
RANBP17
RAN binding protein 17
chr6_+_133562472 0.12 ENST00000430974.2
ENST00000367895.5
ENST00000355167.3
ENST00000355286.6
EYA4
eyes absent homolog 4 (Drosophila)
chr1_+_91966384 0.12 ENST00000430031.2
ENST00000234626.6
CDC7
cell division cycle 7
chr1_+_222988464 0.12 ENST00000420335.1
RP11-452F19.3
RP11-452F19.3
chr10_+_62538089 0.12 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
CDK1
cyclin-dependent kinase 1
chr8_-_74659068 0.12 ENST00000523558.1
ENST00000521210.1
ENST00000355780.5
ENST00000524104.1
ENST00000521736.1
ENST00000521447.1
ENST00000517542.1
ENST00000521451.1
ENST00000521419.1
ENST00000518502.1
ENST00000524300.1
STAU2
staufen double-stranded RNA binding protein 2
chr18_-_812231 0.12 ENST00000314574.4
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr3_-_123680246 0.12 ENST00000488653.2
CCDC14
coiled-coil domain containing 14
chr14_-_64194745 0.12 ENST00000247225.6
SGPP1
sphingosine-1-phosphate phosphatase 1
chr11_+_1855645 0.11 ENST00000381968.3
ENST00000381978.3
SYT8
synaptotagmin VIII
chr2_-_235405679 0.11 ENST00000390645.2
ARL4C
ADP-ribosylation factor-like 4C
chr6_-_127664475 0.11 ENST00000474289.2
ENST00000534442.1
ENST00000368289.2
ENST00000525745.1
ENST00000430841.2
ECHDC1
enoyl CoA hydratase domain containing 1
chr6_+_71377567 0.11 ENST00000422334.2
SMAP1
small ArfGAP 1
chr8_-_494824 0.11 ENST00000427263.2
ENST00000324079.6
TDRP
testis development related protein
chr18_-_6929829 0.11 ENST00000583840.1
ENST00000581571.1
ENST00000578497.1
ENST00000579012.1
LINC00668
long intergenic non-protein coding RNA 668
chr14_-_23791484 0.11 ENST00000594872.1
AL049829.1
Uncharacterized protein
chr7_-_148725544 0.11 ENST00000413966.1
PDIA4
protein disulfide isomerase family A, member 4
chr11_-_8985927 0.11 ENST00000528117.1
ENST00000309134.5
TMEM9B
TMEM9 domain family, member B
chr2_+_197504278 0.11 ENST00000272831.7
ENST00000389175.4
ENST00000472405.2
ENST00000423093.2
CCDC150
coiled-coil domain containing 150
chr1_-_23694794 0.11 ENST00000374608.3
ZNF436
zinc finger protein 436
chr11_-_66445219 0.11 ENST00000525754.1
ENST00000531969.1
ENST00000524637.1
ENST00000531036.2
ENST00000310046.4
RBM4B
RNA binding motif protein 4B
chr9_-_86432547 0.11 ENST00000376365.3
ENST00000376371.2
GKAP1
G kinase anchoring protein 1
chr15_+_80351977 0.11 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
ZFAND6
zinc finger, AN1-type domain 6
chr4_-_107237340 0.11 ENST00000394706.3
TBCK
TBC1 domain containing kinase
chr6_+_111303218 0.11 ENST00000441448.2
RPF2
ribosome production factor 2 homolog (S. cerevisiae)
chr1_+_145611010 0.11 ENST00000369291.5
RNF115
ring finger protein 115
chr4_+_144106063 0.11 ENST00000510377.1
USP38
ubiquitin specific peptidase 38
chr19_+_13122980 0.11 ENST00000590027.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr19_-_37958318 0.11 ENST00000316950.6
ENST00000591710.1
ZNF569
zinc finger protein 569
chr15_+_90777424 0.10 ENST00000561433.1
ENST00000559204.1
ENST00000558291.1
GDPGP1
GDP-D-glucose phosphorylase 1
chr2_+_47630108 0.10 ENST00000233146.2
ENST00000454849.1
ENST00000543555.1
MSH2
mutS homolog 2
chr15_+_40544749 0.10 ENST00000559617.1
ENST00000560684.1
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr17_+_19314432 0.10 ENST00000575165.2
RNF112
ring finger protein 112
chrX_+_100878079 0.10 ENST00000471229.2
ARMCX3
armadillo repeat containing, X-linked 3
chr4_+_159593418 0.10 ENST00000507475.1
ENST00000307738.5
ETFDH
electron-transferring-flavoprotein dehydrogenase
chr17_+_48172639 0.10 ENST00000503176.1
ENST00000503614.1
PDK2
pyruvate dehydrogenase kinase, isozyme 2
chr20_-_34638841 0.10 ENST00000565493.1
LINC00657
long intergenic non-protein coding RNA 657
chr4_+_107236692 0.10 ENST00000510207.1
AIMP1
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
chrX_-_47863348 0.10 ENST00000376943.3
ENST00000396965.1
ENST00000305127.6
ZNF182
zinc finger protein 182
chr19_+_16435625 0.10 ENST00000248071.5
ENST00000592003.1
KLF2
Kruppel-like factor 2
chr11_-_61196858 0.10 ENST00000413184.2
CPSF7
cleavage and polyadenylation specific factor 7, 59kDa
chr5_-_16509101 0.10 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr17_+_10048831 0.10 ENST00000581040.1
AC000003.2
CDNA FLJ25865 fis, clone CBR01927
chr16_+_68279256 0.10 ENST00000564827.2
ENST00000566188.1
ENST00000444212.2
ENST00000568082.1
PLA2G15
phospholipase A2, group XV
chr4_-_107237374 0.10 ENST00000361687.4
ENST00000507696.1
ENST00000394708.2
ENST00000509532.1
TBCK
TBC1 domain containing kinase
chr9_-_21335240 0.10 ENST00000537938.1
KLHL9
kelch-like family member 9
chr3_+_184529929 0.10 ENST00000287546.4
ENST00000437079.3
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr8_+_70404996 0.10 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr19_+_38880695 0.10 ENST00000587947.1
ENST00000338502.4
SPRED3
sprouty-related, EVH1 domain containing 3
chr11_+_32605350 0.10 ENST00000531120.1
ENST00000524896.1
ENST00000323213.5
EIF3M
eukaryotic translation initiation factor 3, subunit M
chr4_+_107236847 0.10 ENST00000358008.3
AIMP1
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
chr11_-_8986474 0.10 ENST00000525069.1
TMEM9B
TMEM9 domain family, member B
chr21_+_34144411 0.10 ENST00000382375.4
ENST00000453404.1
ENST00000382378.1
ENST00000477513.1
C21orf49
chromosome 21 open reading frame 49
chr16_-_14724057 0.09 ENST00000539279.1
ENST00000420015.2
ENST00000437198.2
PARN
poly(A)-specific ribonuclease
chr1_-_11918988 0.09 ENST00000376468.3
NPPB
natriuretic peptide B
chr10_+_94608218 0.09 ENST00000371543.1
EXOC6
exocyst complex component 6
chr6_-_127664683 0.09 ENST00000528402.1
ENST00000454591.2
ECHDC1
enoyl CoA hydratase domain containing 1
chr13_-_73356009 0.09 ENST00000377780.4
ENST00000377767.4
DIS3
DIS3 mitotic control homolog (S. cerevisiae)
chr1_-_202896310 0.09 ENST00000367261.3
KLHL12
kelch-like family member 12

Network of associatons between targets according to the STRING database.

First level regulatory network of RARA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.5 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 0.4 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.1 0.3 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.1 0.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.3 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.2 GO:0015993 molecular hydrogen transport(GO:0015993)
0.1 0.2 GO:0061433 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.1 0.3 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.1 0.2 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.0 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.2 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.6 GO:0097354 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.2 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.0 0.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.0 0.1 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.2 GO:0010520 meiotic gene conversion(GO:0006311) regulation of reciprocal meiotic recombination(GO:0010520)
0.0 0.2 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.2 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.2 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.2 GO:1990262 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0 0.2 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.1 GO:0031392 regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.0 0.2 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.2 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.2 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.3 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.0 0.2 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.2 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.1 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800) renal water absorption(GO:0070295)
0.0 0.3 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.4 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.1 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.2 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.0 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.6 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.1 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.0 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.0 GO:1903524 regulation of vasoconstriction(GO:0019229) vasoconstriction(GO:0042310) positive regulation of blood circulation(GO:1903524)
0.0 0.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.1 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.1 GO:0060702 negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.0 0.2 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.0 0.0 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 0.0 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.2 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.0 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.1 GO:0015820 leucine transport(GO:0015820)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.3 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 0.3 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.1 0.2 GO:0032302 MutSbeta complex(GO:0032302)
0.0 0.7 GO:0005883 neurofilament(GO:0005883)
0.0 0.2 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0005713 recombination nodule(GO:0005713)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.4 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.4 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 0.1 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.5 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.3 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.3 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.1 0.6 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.3 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.1 0.2 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.1 0.6 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.1 0.2 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1 0.2 GO:0032181 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.1 0.3 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.4 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.2 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.0 0.2 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.2 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.1 GO:0004915 interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981)
0.0 0.1 GO:0019808 polyamine binding(GO:0019808)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0016855 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.4 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.1 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.0 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.1 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.1 GO:0004645 phosphorylase activity(GO:0004645)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.7 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions