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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PRDM14

Z-value: 0.53

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Transcription factors associated with PRDM14

Gene Symbol Gene ID Gene Info
PRDM14
ENSG00000147596.3 PR/SET domain 14

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PRDM14hg19_v2_chr8_-_70983506_709835620.701.2e-01Click!

Activity profile of PRDM14 motif

Sorted Z-values of PRDM14 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_156052354 0.28 ENST00000368301.2
LMNA
lamin A/C
chr18_+_57567180 0.27 ENST00000316660.6
ENST00000269518.9
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr13_-_34250861 0.27 ENST00000445227.1
ENST00000454681.2
RP11-141M1.3
RP11-141M1.3
chr1_+_27668505 0.26 ENST00000318074.5
SYTL1
synaptotagmin-like 1
chr15_-_45694380 0.26 ENST00000561148.1
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr4_-_10459009 0.24 ENST00000507515.1
ZNF518B
zinc finger protein 518B
chr3_-_143567262 0.24 ENST00000474151.1
ENST00000316549.6
SLC9A9
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr4_-_103266626 0.20 ENST00000356736.4
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr12_-_76742183 0.20 ENST00000393262.3
BBS10
Bardet-Biedl syndrome 10
chr17_-_19651598 0.20 ENST00000570414.1
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr3_-_134092561 0.20 ENST00000510560.1
ENST00000504234.1
ENST00000515172.1
AMOTL2
angiomotin like 2
chr17_-_19651654 0.19 ENST00000395555.3
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr1_-_116383322 0.18 ENST00000429731.1
NHLH2
nescient helix loop helix 2
chr12_-_52967600 0.15 ENST00000549343.1
ENST00000305620.2
KRT74
keratin 74
chr1_-_33642151 0.14 ENST00000543586.1
TRIM62
tripartite motif containing 62
chr15_+_63188009 0.14 ENST00000557900.1
RP11-1069G10.2
RP11-1069G10.2
chr4_+_141677577 0.13 ENST00000609937.1
RP11-102N12.3
RP11-102N12.3
chr17_-_17726907 0.11 ENST00000423161.3
SREBF1
sterol regulatory element binding transcription factor 1
chr12_+_49760639 0.11 ENST00000549538.1
ENST00000548654.1
ENST00000550643.1
ENST00000548710.1
ENST00000549179.1
ENST00000548377.1
SPATS2
spermatogenesis associated, serine-rich 2
chr20_-_3154162 0.11 ENST00000360342.3
LZTS3
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr1_+_36621529 0.10 ENST00000316156.4
MAP7D1
MAP7 domain containing 1
chr17_+_36873677 0.10 ENST00000471200.1
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr5_-_108063949 0.10 ENST00000606054.1
LINC01023
long intergenic non-protein coding RNA 1023
chr11_+_85566422 0.10 ENST00000342404.3
CCDC83
coiled-coil domain containing 83
chr12_-_56326402 0.10 ENST00000547925.1
WIBG
within bgcn homolog (Drosophila)
chr17_-_19651668 0.09 ENST00000494157.2
ENST00000225740.6
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr19_-_6279932 0.09 ENST00000252674.7
MLLT1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr8_-_102216925 0.08 ENST00000517844.1
ZNF706
zinc finger protein 706
chr5_-_55777586 0.08 ENST00000506836.1
CTC-236F12.4
Uncharacterized protein
chr12_+_121647868 0.08 ENST00000359949.7
ENST00000541532.1
ENST00000543171.1
ENST00000538701.1
P2RX4
purinergic receptor P2X, ligand-gated ion channel, 4
chr3_-_47517302 0.07 ENST00000441517.2
ENST00000545718.1
SCAP
SREBF chaperone
chr14_-_21492113 0.07 ENST00000554094.1
NDRG2
NDRG family member 2
chr2_+_101437487 0.07 ENST00000427413.1
ENST00000542504.1
NPAS2
neuronal PAS domain protein 2
chr2_-_208030886 0.07 ENST00000426163.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr12_+_3600356 0.06 ENST00000382622.3
PRMT8
protein arginine methyltransferase 8
chr17_-_73775839 0.05 ENST00000592643.1
ENST00000591890.1
ENST00000587171.1
ENST00000254810.4
ENST00000589599.1
H3F3B
H3 histone, family 3B (H3.3B)
chr1_+_45274154 0.05 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTBD19
BTB (POZ) domain containing 19
chr19_+_49838653 0.05 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37
CD37 molecule
chr1_+_36621174 0.04 ENST00000429533.2
MAP7D1
MAP7 domain containing 1
chr6_+_43140095 0.04 ENST00000457278.2
SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr4_+_81187753 0.04 ENST00000312465.7
ENST00000456523.3
FGF5
fibroblast growth factor 5
chr11_+_64879317 0.04 ENST00000526809.1
ENST00000279263.7
ENST00000524986.1
ENST00000534371.1
ENST00000540748.1
ENST00000525385.1
ENST00000345348.5
ENST00000531321.1
ENST00000529414.1
ENST00000526085.1
ENST00000530750.1
TM7SF2
transmembrane 7 superfamily member 2
chr17_-_2117600 0.04 ENST00000572369.1
SMG6
SMG6 nonsense mediated mRNA decay factor
chr4_+_4861385 0.04 ENST00000382723.4
MSX1
msh homeobox 1
chr7_-_124405681 0.04 ENST00000303921.2
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr15_+_45694523 0.03 ENST00000305560.6
SPATA5L1
spermatogenesis associated 5-like 1
chrX_+_41193407 0.03 ENST00000457138.2
ENST00000441189.2
DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr10_+_12171636 0.03 ENST00000379051.1
ENST00000379033.3
ENST00000441368.1
ENST00000298428.9
ENST00000304267.8
SEC61A2
Sec61 alpha 2 subunit (S. cerevisiae)
chr2_-_192711968 0.03 ENST00000304141.4
SDPR
serum deprivation response
chr11_-_62474803 0.03 ENST00000533982.1
ENST00000360796.5
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr7_-_30066233 0.03 ENST00000222803.5
FKBP14
FK506 binding protein 14, 22 kDa
chr17_+_41924536 0.02 ENST00000317310.4
CD300LG
CD300 molecule-like family member g
chr6_-_46048116 0.02 ENST00000185206.6
CLIC5
chloride intracellular channel 5
chr14_+_89290965 0.02 ENST00000345383.5
ENST00000536576.1
ENST00000346301.4
ENST00000338104.6
ENST00000354441.6
ENST00000380656.2
ENST00000556651.1
ENST00000554686.1
TTC8
tetratricopeptide repeat domain 8
chr10_+_12171721 0.02 ENST00000379020.4
ENST00000379017.3
SEC61A2
Sec61 alpha 2 subunit (S. cerevisiae)
chr19_-_49314269 0.02 ENST00000545387.2
ENST00000316273.6
ENST00000402551.1
ENST00000598162.1
ENST00000599246.1
BCAT2
branched chain amino-acid transaminase 2, mitochondrial
chr12_+_72332618 0.02 ENST00000333850.3
TPH2
tryptophan hydroxylase 2
chr6_-_109777128 0.02 ENST00000358807.3
ENST00000358577.3
MICAL1
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr14_-_21492251 0.02 ENST00000554398.1
NDRG2
NDRG family member 2
chr12_+_121647962 0.02 ENST00000542067.1
P2RX4
purinergic receptor P2X, ligand-gated ion channel, 4
chr22_-_29457832 0.02 ENST00000216071.4
C22orf31
chromosome 22 open reading frame 31
chr15_+_45694567 0.01 ENST00000559860.1
SPATA5L1
spermatogenesis associated 5-like 1
chr17_-_46691990 0.01 ENST00000576562.1
HOXB8
homeobox B8
chr19_+_3572758 0.01 ENST00000416526.1
HMG20B
high mobility group 20B
chr2_-_145278475 0.01 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr17_+_47653178 0.01 ENST00000328741.5
NXPH3
neurexophilin 3
chr2_+_113033164 0.01 ENST00000409871.1
ENST00000343936.4
ZC3H6
zinc finger CCCH-type containing 6
chr9_+_132099158 0.01 ENST00000444125.1
RP11-65J3.1
RP11-65J3.1
chr1_-_27216729 0.00 ENST00000431781.2
ENST00000374135.4
GPN2
GPN-loop GTPase 2
chr3_-_155394099 0.00 ENST00000414191.1
PLCH1
phospholipase C, eta 1
chr7_+_39989611 0.00 ENST00000181839.4
CDK13
cyclin-dependent kinase 13
chr19_-_5624057 0.00 ENST00000590262.1
SAFB2
scaffold attachment factor B2
chr19_-_49314169 0.00 ENST00000597011.1
ENST00000601681.1
BCAT2
branched chain amino-acid transaminase 2, mitochondrial
chr6_+_72926145 0.00 ENST00000425662.2
ENST00000453976.2
RIMS1
regulating synaptic membrane exocytosis 1

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM14

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0006601 creatine biosynthetic process(GO:0006601)
0.1 0.3 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.3 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.0 0.2 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.0 GO:0061145 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145)
0.0 0.0 GO:0090427 activation of meiosis(GO:0090427)
0.0 0.2 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.0 GO:0000333 telomerase catalytic core complex(GO:0000333)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0015068 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.1 0.5 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.2 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.0 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.1 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)