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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PRDM1

Z-value: 0.77

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Transcription factors associated with PRDM1

Gene Symbol Gene ID Gene Info
PRDM1
ENSG00000057657.10 PR/SET domain 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PRDM1hg19_v2_chr6_+_106534192_106534224-0.572.3e-01Click!

Activity profile of PRDM1 motif

Sorted Z-values of PRDM1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_25205155 0.54 ENST00000550945.1
LRMP
lymphoid-restricted membrane protein
chr21_+_17909594 0.44 ENST00000441820.1
ENST00000602280.1
LINC00478
long intergenic non-protein coding RNA 478
chr19_+_36239576 0.43 ENST00000587751.1
LIN37
lin-37 homolog (C. elegans)
chr12_+_94656297 0.36 ENST00000545312.1
PLXNC1
plexin C1
chr4_-_140544386 0.35 ENST00000561977.1
RP11-308D13.3
RP11-308D13.3
chr17_-_43339474 0.34 ENST00000331780.4
SPATA32
spermatogenesis associated 32
chr12_+_25205446 0.34 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP
lymphoid-restricted membrane protein
chr2_+_145780767 0.31 ENST00000599358.1
ENST00000596278.1
ENST00000596747.1
ENST00000608652.1
ENST00000609705.1
ENST00000608432.1
ENST00000596970.1
ENST00000602041.1
ENST00000601578.1
ENST00000596034.1
ENST00000414195.2
ENST00000594837.1
TEX41
testis expressed 41 (non-protein coding)
chr17_-_43339453 0.28 ENST00000543122.1
SPATA32
spermatogenesis associated 32
chr22_-_36556821 0.27 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
APOL3
apolipoprotein L, 3
chr1_-_221915418 0.26 ENST00000323825.3
ENST00000366899.3
DUSP10
dual specificity phosphatase 10
chr5_+_112227311 0.26 ENST00000391338.1
ZRSR1
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1
chr2_-_70475586 0.26 ENST00000416149.2
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr7_-_105332084 0.26 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr14_+_86401039 0.25 ENST00000557195.1
CTD-2341M24.1
CTD-2341M24.1
chr1_-_119869846 0.23 ENST00000457719.1
RP11-418J17.3
RP11-418J17.3
chr4_-_100242549 0.23 ENST00000305046.8
ENST00000394887.3
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
chr10_-_81203972 0.20 ENST00000372333.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr22_+_39436862 0.19 ENST00000381565.2
ENST00000452957.2
APOBEC3F
APOBEC3G
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
chr7_-_143059780 0.19 ENST00000409578.1
ENST00000409346.1
FAM131B
family with sequence similarity 131, member B
chr6_+_108616243 0.18 ENST00000421954.1
LACE1
lactation elevated 1
chr5_-_39203093 0.18 ENST00000515010.1
FYB
FYN binding protein
chr11_+_46402583 0.18 ENST00000359803.3
MDK
midkine (neurite growth-promoting factor 2)
chr5_-_94417339 0.18 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1
multiple C2 domains, transmembrane 1
chr19_-_17186229 0.17 ENST00000253669.5
ENST00000448593.2
HAUS8
HAUS augmin-like complex, subunit 8
chr11_+_46402744 0.17 ENST00000533952.1
MDK
midkine (neurite growth-promoting factor 2)
chr14_-_21490653 0.16 ENST00000449431.2
NDRG2
NDRG family member 2
chr3_+_51977294 0.16 ENST00000498510.1
PARP3
poly (ADP-ribose) polymerase family, member 3
chr7_-_143059845 0.16 ENST00000443739.2
FAM131B
family with sequence similarity 131, member B
chr13_+_31309645 0.16 ENST00000380490.3
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr10_+_91589309 0.15 ENST00000448490.1
LINC00865
long intergenic non-protein coding RNA 865
chr2_-_231084820 0.15 ENST00000258382.5
ENST00000338556.3
SP110
SP110 nuclear body protein
chr10_-_82049424 0.15 ENST00000372213.3
MAT1A
methionine adenosyltransferase I, alpha
chr5_-_94417562 0.15 ENST00000505465.1
MCTP1
multiple C2 domains, transmembrane 1
chr8_-_29120604 0.15 ENST00000521515.1
KIF13B
kinesin family member 13B
chr18_+_3466248 0.14 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
RP11-838N2.4
chr20_+_388935 0.14 ENST00000382181.2
ENST00000400247.3
RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chr14_-_23479331 0.14 ENST00000397377.1
ENST00000397379.3
ENST00000406429.2
ENST00000341470.4
ENST00000555998.1
ENST00000397376.2
ENST00000553675.1
ENST00000553931.1
ENST00000555575.1
ENST00000553958.1
ENST00000555098.1
ENST00000556419.1
ENST00000553606.1
ENST00000299088.6
ENST00000554179.1
ENST00000397382.4
C14orf93
chromosome 14 open reading frame 93
chr1_+_110453514 0.14 ENST00000369802.3
ENST00000420111.2
CSF1
colony stimulating factor 1 (macrophage)
chr3_-_64431058 0.14 ENST00000564377.1
PRICKLE2
prickle homolog 2 (Drosophila)
chr3_+_8543561 0.14 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr6_+_130339710 0.14 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr1_+_212782012 0.14 ENST00000341491.4
ENST00000366985.1
ATF3
activating transcription factor 3
chr4_+_152020715 0.13 ENST00000274065.4
RPS3A
ribosomal protein S3A
chr6_-_167276033 0.13 ENST00000503859.1
ENST00000506565.1
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr12_-_54653313 0.13 ENST00000550411.1
ENST00000439541.2
CBX5
chromobox homolog 5
chr20_-_18774614 0.13 ENST00000412553.1
LINC00652
long intergenic non-protein coding RNA 652
chr3_-_4793274 0.13 ENST00000414938.1
EGOT
eosinophil granule ontogeny transcript (non-protein coding)
chr7_+_95401851 0.13 ENST00000447467.2
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr10_+_91589261 0.13 ENST00000448963.1
LINC00865
long intergenic non-protein coding RNA 865
chr12_+_6561190 0.12 ENST00000544021.1
ENST00000266556.7
TAPBPL
TAP binding protein-like
chr5_-_96143602 0.12 ENST00000443439.2
ENST00000503921.1
ENST00000508227.1
ENST00000507154.1
ERAP1
endoplasmic reticulum aminopeptidase 1
chr1_+_110453109 0.12 ENST00000525659.1
CSF1
colony stimulating factor 1 (macrophage)
chr4_+_152020789 0.12 ENST00000512690.1
ENST00000508783.1
ENST00000512797.1
ENST00000507327.1
ENST00000515792.1
ENST00000506126.1
RPS3A
ribosomal protein S3A
chr4_+_186990298 0.12 ENST00000296795.3
ENST00000513189.1
TLR3
toll-like receptor 3
chr4_+_152020736 0.12 ENST00000509736.1
ENST00000505243.1
ENST00000514682.1
ENST00000322686.6
ENST00000503002.1
RPS3A
ribosomal protein S3A
chr7_-_111424462 0.12 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr12_-_120763739 0.11 ENST00000549767.1
PLA2G1B
phospholipase A2, group IB (pancreas)
chr11_+_46402297 0.11 ENST00000405308.2
MDK
midkine (neurite growth-promoting factor 2)
chr11_+_46402482 0.11 ENST00000441869.1
MDK
midkine (neurite growth-promoting factor 2)
chrX_+_10124977 0.11 ENST00000380833.4
CLCN4
chloride channel, voltage-sensitive 4
chr8_+_97506033 0.11 ENST00000518385.1
SDC2
syndecan 2
chr21_+_22370717 0.11 ENST00000284894.7
NCAM2
neural cell adhesion molecule 2
chr6_-_105584560 0.11 ENST00000336775.5
BVES
blood vessel epicardial substance
chr6_+_106535455 0.11 ENST00000424894.1
PRDM1
PR domain containing 1, with ZNF domain
chr5_-_39274617 0.11 ENST00000510188.1
FYB
FYN binding protein
chr1_+_2487631 0.11 ENST00000409119.1
TNFRSF14
tumor necrosis factor receptor superfamily, member 14
chr7_+_95401877 0.11 ENST00000524053.1
ENST00000324972.6
ENST00000537881.1
ENST00000437599.1
ENST00000359388.4
ENST00000413338.1
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr15_+_85144217 0.11 ENST00000540936.1
ENST00000448803.2
ENST00000546275.1
ENST00000546148.1
ENST00000442073.3
ENST00000334141.3
ENST00000358472.3
ENST00000502939.2
ENST00000379358.3
ENST00000327179.6
ZSCAN2
zinc finger and SCAN domain containing 2
chr3_+_8543393 0.10 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1
LIM and cysteine-rich domains 1
chr11_-_796197 0.10 ENST00000530360.1
ENST00000528606.1
ENST00000320230.5
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr2_+_166150541 0.10 ENST00000283256.6
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr2_+_234545148 0.10 ENST00000373445.1
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr3_+_47422485 0.10 ENST00000431726.1
ENST00000456221.1
ENST00000265562.4
PTPN23
protein tyrosine phosphatase, non-receptor type 23
chr3_+_107241882 0.10 ENST00000416476.2
BBX
bobby sox homolog (Drosophila)
chr9_+_133454943 0.10 ENST00000319725.9
FUBP3
far upstream element (FUSE) binding protein 3
chr7_+_7811992 0.10 ENST00000406829.1
RPA3-AS1
RPA3 antisense RNA 1
chr4_+_146403912 0.10 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD1
SMAD family member 1
chr18_-_47017956 0.09 ENST00000584895.1
ENST00000332968.6
ENST00000580210.1
ENST00000579408.1
RPL17-C18orf32
RPL17
RPL17-C18orf32 readthrough
ribosomal protein L17
chr4_-_100140331 0.09 ENST00000407820.2
ENST00000394897.1
ENST00000508558.1
ENST00000394899.2
ADH6
alcohol dehydrogenase 6 (class V)
chr2_+_69240415 0.09 ENST00000409829.3
ANTXR1
anthrax toxin receptor 1
chr12_+_51317788 0.09 ENST00000550502.1
METTL7A
methyltransferase like 7A
chr12_+_51318513 0.09 ENST00000332160.4
METTL7A
methyltransferase like 7A
chr15_+_71185148 0.09 ENST00000443425.2
ENST00000560755.1
LRRC49
leucine rich repeat containing 49
chr2_+_175260514 0.09 ENST00000424069.1
ENST00000427038.1
SCRN3
secernin 3
chr20_-_5100591 0.09 ENST00000379143.5
PCNA
proliferating cell nuclear antigen
chr1_+_2985760 0.09 ENST00000378391.2
ENST00000514189.1
ENST00000270722.5
PRDM16
PR domain containing 16
chr2_-_202508169 0.09 ENST00000409883.2
TMEM237
transmembrane protein 237
chr8_-_142012169 0.09 ENST00000517453.1
PTK2
protein tyrosine kinase 2
chr2_+_145780739 0.08 ENST00000597173.1
ENST00000602108.1
ENST00000420472.1
TEX41
testis expressed 41 (non-protein coding)
chr4_+_142557771 0.08 ENST00000514653.1
IL15
interleukin 15
chr3_-_46000064 0.08 ENST00000433878.1
FYCO1
FYVE and coiled-coil domain containing 1
chr8_-_29120580 0.08 ENST00000524189.1
KIF13B
kinesin family member 13B
chr1_+_2985726 0.08 ENST00000511072.1
ENST00000378398.3
ENST00000441472.2
ENST00000442529.2
PRDM16
PR domain containing 16
chr15_-_72565340 0.08 ENST00000568360.1
PARP6
poly (ADP-ribose) polymerase family, member 6
chr13_+_108921977 0.07 ENST00000430559.1
ENST00000375887.4
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr19_+_13106383 0.07 ENST00000397661.2
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr12_-_57504975 0.07 ENST00000553397.1
ENST00000556259.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr22_-_31688431 0.07 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr14_-_21490958 0.07 ENST00000554104.1
NDRG2
NDRG family member 2
chr10_+_62538089 0.07 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
CDK1
cyclin-dependent kinase 1
chr9_+_137533615 0.07 ENST00000371817.3
COL5A1
collagen, type V, alpha 1
chr1_-_182361327 0.07 ENST00000331872.6
ENST00000311223.5
GLUL
glutamate-ammonia ligase
chr17_-_79818354 0.07 ENST00000576541.1
ENST00000576380.1
ENST00000571617.1
ENST00000576052.1
ENST00000576390.1
ENST00000573778.2
ENST00000439918.2
ENST00000574914.1
ENST00000331483.4
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr15_-_37393406 0.06 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr11_+_71710973 0.06 ENST00000393707.4
IL18BP
interleukin 18 binding protein
chr2_+_234545092 0.06 ENST00000344644.5
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr11_+_71710648 0.06 ENST00000260049.5
IL18BP
interleukin 18 binding protein
chr2_+_234526272 0.06 ENST00000373450.4
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr21_-_35899113 0.06 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1
regulator of calcineurin 1
chr8_-_116681221 0.06 ENST00000395715.3
TRPS1
trichorhinophalangeal syndrome I
chr4_-_74088800 0.06 ENST00000509867.2
ANKRD17
ankyrin repeat domain 17
chr14_-_24615805 0.06 ENST00000560410.1
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr1_-_153919128 0.06 ENST00000361217.4
DENND4B
DENN/MADD domain containing 4B
chr14_+_24605361 0.06 ENST00000206451.6
ENST00000559123.1
PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr1_-_111746966 0.06 ENST00000369752.5
DENND2D
DENN/MADD domain containing 2D
chr2_+_234590556 0.06 ENST00000373426.3
UGT1A7
UDP glucuronosyltransferase 1 family, polypeptide A7
chr6_+_152011628 0.06 ENST00000404742.1
ENST00000440973.1
ESR1
estrogen receptor 1
chr17_+_41158742 0.05 ENST00000415816.2
ENST00000438323.2
IFI35
interferon-induced protein 35
chr6_-_99797522 0.05 ENST00000389677.5
FAXC
failed axon connections homolog (Drosophila)
chr9_+_67968793 0.05 ENST00000417488.1
RP11-195B21.3
Protein LOC644249
chr2_-_175260368 0.05 ENST00000342016.3
ENST00000362053.5
CIR1
corepressor interacting with RBPJ, 1
chr6_-_33281979 0.05 ENST00000426633.2
ENST00000467025.1
TAPBP
TAP binding protein (tapasin)
chr1_-_8483723 0.05 ENST00000476556.1
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr6_-_154831779 0.05 ENST00000607772.1
CNKSR3
CNKSR family member 3
chr18_-_53070913 0.05 ENST00000568186.1
ENST00000564228.1
TCF4
transcription factor 4
chr5_-_96143796 0.05 ENST00000296754.3
ERAP1
endoplasmic reticulum aminopeptidase 1
chr2_+_69240302 0.05 ENST00000303714.4
ANTXR1
anthrax toxin receptor 1
chr22_-_31688381 0.05 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr4_+_142558078 0.05 ENST00000529613.1
IL15
interleukin 15
chr8_+_77593448 0.05 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr3_-_149375783 0.04 ENST00000467467.1
ENST00000460517.1
ENST00000360632.3
WWTR1
WW domain containing transcription regulator 1
chr12_-_50561075 0.04 ENST00000422340.2
ENST00000317551.6
CERS5
ceramide synthase 5
chr10_-_131762105 0.04 ENST00000368648.3
ENST00000355311.5
EBF3
early B-cell factor 3
chr1_+_151372010 0.04 ENST00000290541.6
PSMB4
proteasome (prosome, macropain) subunit, beta type, 4
chr9_+_84304628 0.04 ENST00000437181.1
RP11-154D17.1
RP11-154D17.1
chr7_+_134832808 0.04 ENST00000275767.3
TMEM140
transmembrane protein 140
chr5_+_92919043 0.04 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr17_-_56606664 0.04 ENST00000580844.1
SEPT4
septin 4
chr6_+_118869452 0.04 ENST00000357525.5
PLN
phospholamban
chr10_+_18429671 0.04 ENST00000282343.8
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chrX_-_63005405 0.04 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr17_-_56606639 0.04 ENST00000579371.1
SEPT4
septin 4
chr22_-_36635598 0.04 ENST00000454728.1
APOL2
apolipoprotein L, 2
chr19_+_19516561 0.04 ENST00000457895.2
GATAD2A
GATA zinc finger domain containing 2A
chr6_-_29527702 0.04 ENST00000377050.4
UBD
ubiquitin D
chr6_+_53659746 0.04 ENST00000370888.1
LRRC1
leucine rich repeat containing 1
chr7_+_134464376 0.04 ENST00000454108.1
ENST00000361675.2
CALD1
caldesmon 1
chr11_-_96076334 0.04 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr14_+_24605389 0.03 ENST00000382708.3
ENST00000561435.1
PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr5_+_76506706 0.03 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
PDE8B
phosphodiesterase 8B
chr18_+_34124507 0.03 ENST00000591635.1
FHOD3
formin homology 2 domain containing 3
chr2_-_231084617 0.03 ENST00000409815.2
SP110
SP110 nuclear body protein
chr7_+_128355439 0.03 ENST00000315184.5
FAM71F1
family with sequence similarity 71, member F1
chrX_-_139015153 0.03 ENST00000370557.1
ATP11C
ATPase, class VI, type 11C
chr19_-_43032532 0.03 ENST00000403461.1
ENST00000352591.5
ENST00000358394.3
ENST00000403444.3
ENST00000308072.4
ENST00000599389.1
ENST00000351134.3
ENST00000161559.6
CEACAM1
carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
chr17_-_56606705 0.03 ENST00000317268.3
SEPT4
septin 4
chr12_-_95941987 0.03 ENST00000537435.2
USP44
ubiquitin specific peptidase 44
chr1_+_110453608 0.03 ENST00000369801.1
CSF1
colony stimulating factor 1 (macrophage)
chr1_+_110453203 0.03 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1
colony stimulating factor 1 (macrophage)
chr11_+_71709938 0.03 ENST00000393705.4
ENST00000337131.5
ENST00000531053.1
ENST00000404792.1
IL18BP
interleukin 18 binding protein
chr9_+_18474098 0.03 ENST00000327883.7
ENST00000431052.2
ENST00000380570.4
ADAMTSL1
ADAMTS-like 1
chr2_-_223163465 0.03 ENST00000409828.3
ENST00000350526.4
ENST00000258387.5
ENST00000409551.3
ENST00000392069.2
ENST00000344493.4
ENST00000336840.6
ENST00000392070.2
PAX3
paired box 3
chr1_-_151735937 0.03 ENST00000368829.3
ENST00000368830.3
MRPL9
mitochondrial ribosomal protein L9
chrX_+_114874727 0.03 ENST00000543070.1
PLS3
plastin 3
chr6_-_167275991 0.03 ENST00000510118.1
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr20_+_13976015 0.03 ENST00000217246.4
MACROD2
MACRO domain containing 2
chr1_-_161014731 0.03 ENST00000368020.1
USF1
upstream transcription factor 1
chr12_+_57916584 0.03 ENST00000546632.1
ENST00000549623.1
ENST00000431731.2
MBD6
methyl-CpG binding domain protein 6
chr9_+_18474204 0.03 ENST00000276935.6
ADAMTSL1
ADAMTS-like 1
chr10_-_112678692 0.03 ENST00000605742.1
BBIP1
BBSome interacting protein 1
chr6_-_41909191 0.03 ENST00000512426.1
ENST00000372987.4
CCND3
cyclin D3
chr16_-_72206034 0.03 ENST00000537465.1
ENST00000237353.10
PMFBP1
polyamine modulated factor 1 binding protein 1
chr16_+_10972818 0.02 ENST00000576601.1
CIITA
class II, major histocompatibility complex, transactivator
chr2_+_231191875 0.02 ENST00000444636.1
ENST00000415673.2
ENST00000243810.6
ENST00000396563.4
SP140L
SP140 nuclear body protein-like
chr11_-_85338311 0.02 ENST00000376104.2
DLG2
discs, large homolog 2 (Drosophila)
chr10_-_35104185 0.02 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
PARD3
par-3 family cell polarity regulator
chr16_-_3930724 0.02 ENST00000262367.5
CREBBP
CREB binding protein
chr5_+_96212185 0.02 ENST00000379904.4
ERAP2
endoplasmic reticulum aminopeptidase 2
chr2_-_145275228 0.02 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
ZEB2
zinc finger E-box binding homeobox 2
chr4_+_142557717 0.02 ENST00000320650.4
ENST00000296545.7
IL15
interleukin 15
chr4_-_153303658 0.02 ENST00000296555.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr10_-_50747064 0.02 ENST00000355832.5
ENST00000603152.1
ENST00000447839.2
ERCC6
PGBD3
ERCC6-PGBD3
excision repair cross-complementing rodent repair deficiency, complementation group 6
piggyBac transposable element derived 3
ERCC6-PGBD3 readthrough
chr15_+_75491203 0.02 ENST00000562637.1
C15orf39
chromosome 15 open reading frame 39
chr19_+_17186577 0.02 ENST00000595618.1
ENST00000594824.1
MYO9B
myosin IXB
chr8_+_125860939 0.02 ENST00000525292.1
ENST00000528090.1
LINC00964
long intergenic non-protein coding RNA 964
chr18_+_12947126 0.02 ENST00000592170.1
SEH1L
SEH1-like (S. cerevisiae)
chr2_-_231084659 0.02 ENST00000258381.6
ENST00000358662.4
ENST00000455674.1
ENST00000392048.3
SP110
SP110 nuclear body protein
chr10_-_73976884 0.02 ENST00000317126.4
ENST00000545550.1
ASCC1
activating signal cointegrator 1 complex subunit 1
chr3_-_168864427 0.02 ENST00000468789.1
MECOM
MDS1 and EVI1 complex locus
chr22_-_36635684 0.02 ENST00000358502.5
APOL2
apolipoprotein L, 2
chr1_-_182360918 0.02 ENST00000339526.4
GLUL
glutamate-ammonia ligase
chr6_-_137113604 0.02 ENST00000359015.4
MAP3K5
mitogen-activated protein kinase kinase kinase 5
chr6_+_146348782 0.02 ENST00000361719.2
ENST00000392299.2
GRM1
glutamate receptor, metabotropic 1
chr20_+_388679 0.02 ENST00000356286.5
ENST00000475269.1
RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chr14_-_21490417 0.02 ENST00000556366.1
NDRG2
NDRG family member 2
chr8_+_77593474 0.01 ENST00000455469.2
ENST00000050961.6
ZFHX4
zinc finger homeobox 4
chr6_+_127439749 0.01 ENST00000356698.4
RSPO3
R-spondin 3
chr1_+_11832179 0.01 ENST00000312793.5
C1orf167
chromosome 1 open reading frame 167
chr3_+_107241783 0.01 ENST00000415149.2
ENST00000402543.1
ENST00000325805.8
ENST00000427402.1
BBX
bobby sox homolog (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0030421 defecation(GO:0030421)
0.1 0.3 GO:1904139 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) positive regulation of microglial cell migration(GO:1904141)
0.1 0.3 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536) regulation of respiratory burst involved in inflammatory response(GO:0060264) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.2 GO:0045062 extrathymic T cell selection(GO:0045062)
0.0 0.1 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.1 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.0 0.1 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.0 0.1 GO:0060931 sinoatrial node cell development(GO:0060931)
0.0 0.3 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.2 GO:0070383 DNA cytosine deamination(GO:0070383)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0 0.3 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.2 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.0 0.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.2 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.3 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.2 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 0.2 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.0 GO:1902080 negative regulation of calcium-transporting ATPase activity(GO:1901895) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.0 0.0 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.0 GO:0043317 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859) regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.3 GO:0089701 U2AF(GO:0089701)
0.0 0.3 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.2 GO:0042007 interleukin-18 binding(GO:0042007)
0.0 0.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.2 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.2 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 0.3 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.1 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.3 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.2 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.1 GO:0008267 poly-glutamine tract binding(GO:0008267)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions