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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PPARG

Z-value: 0.90

Motif logo

Transcription factors associated with PPARG

Gene Symbol Gene ID Gene Info
ENSG00000132170.15 peroxisome proliferator activated receptor gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PPARGhg19_v2_chr3_+_12329397_12329433-0.711.1e-01Click!

Activity profile of PPARG motif

Sorted Z-values of PPARG motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_153433120 0.83 ENST00000368723.3
S100 calcium binding protein A7
chr19_+_49661037 0.77 ENST00000427978.2
transient receptor potential cation channel, subfamily M, member 4
chr19_-_1592828 0.74 ENST00000592012.1
methyl-CpG binding domain protein 3
chr5_+_131409476 0.71 ENST00000296871.2
colony stimulating factor 2 (granulocyte-macrophage)
chr5_-_150460539 0.64 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
TNFAIP3 interacting protein 1
chr19_+_49660997 0.53 ENST00000598691.1
ENST00000252826.5
transient receptor potential cation channel, subfamily M, member 4
chr19_+_49661079 0.52 ENST00000355712.5
transient receptor potential cation channel, subfamily M, member 4
chr8_-_10336885 0.45 ENST00000520494.1
RP11-981G7.3
chr4_+_57371509 0.44 ENST00000360096.2
ADP-ribosylation factor-like 9
chr14_+_24630465 0.44 ENST00000557894.1
ENST00000559284.1
ENST00000560275.1
interferon regulatory factor 9
chr11_+_65686952 0.42 ENST00000527119.1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr22_+_22676808 0.39 ENST00000390290.2
immunoglobulin lambda variable 1-51
chr12_+_66582919 0.37 ENST00000545837.1
ENST00000457197.2
interleukin-1 receptor-associated kinase 3
chr8_-_145641864 0.36 ENST00000276833.5
solute carrier family 39 (zinc transporter), member 4
chr20_+_43803517 0.36 ENST00000243924.3
peptidase inhibitor 3, skin-derived
chr19_-_2783255 0.34 ENST00000589251.1
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr22_+_23264766 0.33 ENST00000390331.2
immunoglobulin lambda constant 7
chr22_+_50312316 0.33 ENST00000328268.4
cysteine-rich with EGF-like domains 2
chr19_-_1592652 0.33 ENST00000156825.1
ENST00000434436.3
methyl-CpG binding domain protein 3
chr19_-_7698599 0.32 ENST00000311069.5
Purkinje cell protein 2
chr8_-_145642267 0.32 ENST00000301305.3
solute carrier family 39 (zinc transporter), member 4
chr5_-_180242576 0.32 ENST00000514438.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr9_+_140119618 0.31 ENST00000359069.2
chromosome 9 open reading frame 169
chr15_-_34502197 0.31 ENST00000557877.1
katanin p80 subunit B-like 1
chr6_+_31783291 0.30 ENST00000375651.5
ENST00000608703.1
ENST00000458062.2
heat shock 70kDa protein 1A
chr11_+_65687158 0.30 ENST00000532933.1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr6_+_31795506 0.29 ENST00000375650.3
heat shock 70kDa protein 1B
chr5_-_70272055 0.29 ENST00000514857.2
NLR family, apoptosis inhibitory protein
chr5_+_38445641 0.28 ENST00000397210.3
ENST00000506135.1
ENST00000508131.1
EGF-like, fibronectin type III and laminin G domains
chr4_+_74735102 0.27 ENST00000395761.3
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr22_+_31277661 0.27 ENST00000454145.1
ENST00000453621.1
ENST00000431368.1
ENST00000535268.1
oxysterol binding protein 2
chr6_-_112575758 0.27 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
laminin, alpha 4
chr4_-_860950 0.25 ENST00000511980.1
ENST00000510799.1
cyclin G associated kinase
chr19_-_51587502 0.25 ENST00000156499.2
ENST00000391802.1
kallikrein-related peptidase 14
chr14_+_23341513 0.25 ENST00000546834.1
low density lipoprotein receptor-related protein 10
chr15_+_41056218 0.24 ENST00000260447.4
GTP cyclohydrolase I feedback regulator
chr6_-_43478239 0.23 ENST00000372441.1
leucine rich repeat containing 73
chr19_+_7968728 0.23 ENST00000397981.3
ENST00000545011.1
ENST00000397983.3
ENST00000397979.3
mitogen-activated protein kinase kinase 7
chr17_-_79792909 0.22 ENST00000330261.4
ENST00000570394.1
protein phosphatase 1, regulatory subunit 27
chr17_-_76975925 0.21 ENST00000591274.1
ENST00000589906.1
ENST00000591778.1
ENST00000589775.2
ENST00000585407.1
ENST00000262776.3
lectin, galactoside-binding, soluble, 3 binding protein
chr19_+_532049 0.21 ENST00000606136.1
cell division cycle 34
chr9_+_130469257 0.21 ENST00000373295.2
chromosome 9 open reading frame 117
chr10_+_4828815 0.21 ENST00000533295.1
aldo-keto reductase family 1, member E2
chr22_+_50312274 0.20 ENST00000404488.3
cysteine-rich with EGF-like domains 2
chr11_-_65667997 0.20 ENST00000312562.2
ENST00000534222.1
FOS-like antigen 1
chr1_-_206288647 0.19 ENST00000331555.5
chromosome 1 open reading frame 186
chr19_+_751122 0.19 ENST00000215582.6
mitotic spindle positioning
chr1_-_16482554 0.19 ENST00000358432.5
EPH receptor A2
chr19_+_42388437 0.19 ENST00000378152.4
ENST00000337665.4
Rho guanine nucleotide exchange factor (GEF) 1
chr12_-_80084594 0.19 ENST00000548426.1
PRKC, apoptosis, WT1, regulator
chr15_-_41166414 0.19 ENST00000220507.4
ras homolog family member V
chr11_+_65686728 0.19 ENST00000312515.2
ENST00000525501.1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr11_-_9025541 0.19 ENST00000525100.1
ENST00000309166.3
ENST00000531090.1
nuclear receptor interacting protein 3
chr11_-_65686496 0.19 ENST00000449692.3
chromosome 11 open reading frame 68
chr11_+_308143 0.18 ENST00000399817.4
interferon induced transmembrane protein 2
chr8_+_145729465 0.18 ENST00000394955.2
glutamic-pyruvate transaminase (alanine aminotransferase)
chr5_+_176731572 0.18 ENST00000503853.1
PRELI domain containing 1
chr7_+_80253387 0.18 ENST00000438020.1
CD36 molecule (thrombospondin receptor)
chr11_+_844406 0.17 ENST00000397404.1
tetraspanin 4
chr19_+_531713 0.17 ENST00000215574.4
cell division cycle 34
chr3_-_139195350 0.17 ENST00000232217.2
retinol binding protein 2, cellular
chr11_-_1593150 0.17 ENST00000397374.3
dual specificity phosphatase 8
chr22_-_36784035 0.17 ENST00000216181.5
myosin, heavy chain 9, non-muscle
chr19_-_13068012 0.17 ENST00000316939.1
growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr19_+_17970677 0.17 ENST00000222247.5
ribosomal protein L18a
chr2_+_112813134 0.17 ENST00000452614.1
transmembrane protein 87B
chr2_+_120187465 0.17 ENST00000409826.1
ENST00000417645.1
transmembrane protein 37
chr11_-_67210930 0.17 ENST00000453768.2
ENST00000545016.1
ENST00000341356.5
coronin, actin binding protein, 1B
chr9_+_101984577 0.17 ENST00000223641.4
Sec61 beta subunit
chr17_+_18128896 0.17 ENST00000316843.4
lethal giant larvae homolog 1 (Drosophila)
chr19_-_17014408 0.17 ENST00000594249.1
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr8_-_145652336 0.16 ENST00000529182.1
ENST00000526054.1
vacuolar protein sorting 28 homolog (S. cerevisiae)
chr19_+_56154913 0.16 ENST00000270451.5
ENST00000588537.1
zinc finger protein 581
chr14_+_95047725 0.16 ENST00000554760.1
ENST00000554866.1
ENST00000329597.7
ENST00000556775.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr11_+_75479763 0.16 ENST00000228027.7
diacylglycerol O-acyltransferase 2
chr8_+_145203548 0.16 ENST00000534366.1
maestro heat-like repeat family member 1
chr1_+_3385085 0.16 ENST00000445297.1
Rho guanine nucleotide exchange factor (GEF) 16
chr17_-_48450534 0.16 ENST00000503633.1
ENST00000442592.3
ENST00000225969.4
mitochondrial ribosomal protein L27
chr19_-_5680202 0.16 ENST00000590389.1
chromosome 19 open reading frame 70
chr19_-_2783363 0.15 ENST00000221566.2
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr11_-_65686586 0.15 ENST00000438576.2
chromosome 11 open reading frame 68
chr1_+_114473350 0.15 ENST00000503968.1
homeodomain interacting protein kinase 1
chr11_-_7904464 0.15 ENST00000502624.2
ENST00000527565.1
RP11-35J10.5
chr5_-_43483929 0.15 ENST00000500337.2
ENST00000506860.1
ENST00000510130.1
ENST00000397080.3
ENST00000512085.1
chromosome 5 open reading frame 28
chr2_-_74779744 0.15 ENST00000409249.1
lysyl oxidase-like 3
chr16_+_20912075 0.15 ENST00000219168.4
LYR motif containing 1
chr16_+_8768422 0.15 ENST00000268251.8
ENST00000564714.1
4-aminobutyrate aminotransferase
chr16_+_2570340 0.15 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
amidohydrolase domain containing 2
chr6_+_31465892 0.15 ENST00000252229.6
ENST00000427115.1
MHC class I polypeptide-related sequence B
chr3_+_99357319 0.15 ENST00000452013.1
ENST00000261037.3
ENST00000273342.4
collagen, type VIII, alpha 1
chr1_+_153388993 0.14 ENST00000368729.4
S100 calcium binding protein A7A
chr16_+_84209738 0.14 ENST00000564928.1
dynein, axonemal, assembly factor 1
chr19_+_3506261 0.14 ENST00000441788.2
fizzy/cell division cycle 20 related 1 (Drosophila)
chr11_+_60609537 0.14 ENST00000227520.5
coiled-coil domain containing 86
chr6_+_31465849 0.14 ENST00000399150.3
MHC class I polypeptide-related sequence B
chr11_-_64052111 0.14 ENST00000394532.3
ENST00000394531.3
ENST00000309032.3
BCL2-associated agonist of cell death
chr6_-_112575912 0.14 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
laminin, alpha 4
chr19_-_44031341 0.14 ENST00000600651.1
ethylmalonic encephalopathy 1
chr8_-_9009079 0.14 ENST00000519699.1
protein phosphatase 1, regulatory subunit 3B
chr15_+_41186637 0.13 ENST00000558474.1
vacuolar protein sorting 18 homolog (S. cerevisiae)
chr19_+_4343691 0.13 ENST00000597036.1
MPN domain containing
chr19_+_45349630 0.13 ENST00000252483.5
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr15_+_40675132 0.13 ENST00000608100.1
ENST00000557920.1
kinetochore-localized astrin/SPAG5 binding protein
chr1_-_1009683 0.13 ENST00000453464.2
ring finger protein 223
chr11_+_126225789 0.13 ENST00000530591.1
ENST00000534083.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr8_-_145020560 0.13 ENST00000526416.1
plectin
chr1_+_217804661 0.13 ENST00000366933.4
spermatogenesis associated 17
chr11_-_62439727 0.13 ENST00000528862.1
chromosome 11 open reading frame 48
chr22_+_50312379 0.13 ENST00000407217.3
ENST00000403427.3
cysteine-rich with EGF-like domains 2
chr19_-_5680231 0.13 ENST00000587950.1
chromosome 19 open reading frame 70
chr19_+_50016411 0.13 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
Fc fragment of IgG, receptor, transporter, alpha
chr5_+_149865377 0.13 ENST00000522491.1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr22_+_20008678 0.12 ENST00000434168.1
transport and golgi organization 2 homolog (Drosophila)
chr17_-_62097927 0.12 ENST00000578313.1
ENST00000584084.1
ENST00000579788.1
ENST00000579687.1
ENST00000578379.1
ENST00000578892.1
ENST00000412356.1
ENST00000418105.1
intercellular adhesion molecule 2
chr20_+_44563267 0.12 ENST00000372409.3
PDX1 C-terminal inhibiting factor 1
chr21_-_46954529 0.12 ENST00000485649.2
solute carrier family 19 (folate transporter), member 1
chr15_+_41186609 0.12 ENST00000220509.5
vacuolar protein sorting 18 homolog (S. cerevisiae)
chr11_-_65640071 0.12 ENST00000526624.1
EGF containing fibulin-like extracellular matrix protein 2
chr16_+_476379 0.12 ENST00000434585.1
RAB11 family interacting protein 3 (class II)
chr20_-_3748416 0.12 ENST00000399672.1
chromosome 20 open reading frame 27
chr2_-_27357479 0.12 ENST00000406567.3
ENST00000260643.2
prolactin regulatory element binding
chr19_-_55919087 0.12 ENST00000587845.1
ENST00000589978.1
ENST00000264552.9
ubiquitin-conjugating enzyme E2S
chr7_-_100425112 0.12 ENST00000358173.3
EPH receptor B4
chr5_-_179107975 0.12 ENST00000376974.4
chibby homolog 3 (Drosophila)
chr19_-_16653325 0.12 ENST00000546361.2
calcium homeostasis endoplasmic reticulum protein
chr9_-_117150243 0.12 ENST00000374088.3
AT-hook transcription factor
chr11_+_68816356 0.12 ENST00000294309.3
ENST00000542467.1
two pore segment channel 2
chr12_-_129308041 0.11 ENST00000376740.4
solute carrier family 15 (oligopeptide transporter), member 4
chr2_+_232575128 0.11 ENST00000412128.1
prothymosin, alpha
chrX_-_48325857 0.11 ENST00000376875.1
solute carrier family 38, member 5
chr16_-_3137080 0.11 ENST00000574387.1
ENST00000571404.1
RP11-473M20.9
chr22_+_19929130 0.11 ENST00000361682.6
ENST00000403184.1
ENST00000403710.1
ENST00000407537.1
catechol-O-methyltransferase
chr16_+_50730910 0.11 ENST00000300589.2
nucleotide-binding oligomerization domain containing 2
chr9_+_139847347 0.11 ENST00000371632.3
lipocalin 12
chr16_-_89883015 0.11 ENST00000563673.1
ENST00000389301.3
ENST00000568369.1
ENST00000534992.1
ENST00000389302.3
ENST00000543736.1
Fanconi anemia, complementation group A
chr21_-_46293644 0.11 ENST00000330938.3
pituitary tumor-transforming 1 interacting protein
chr22_+_31488433 0.11 ENST00000455608.1
smoothelin
chr19_+_4472230 0.11 ENST00000301284.4
ENST00000586684.1
Hepatoma-derived growth factor-related protein 2
chr16_+_2961973 0.11 ENST00000399667.2
ENST00000416288.2
ENST00000570425.1
ENST00000573525.1
FLYWCH-type zinc finger 1
chr19_-_16653226 0.11 ENST00000198939.6
calcium homeostasis endoplasmic reticulum protein
chr16_-_4850471 0.11 ENST00000592019.1
ENST00000586153.1
rogdi homolog (Drosophila)
chr16_+_29831715 0.11 ENST00000563915.1
ENST00000357402.5
major vault protein
chr2_-_74619152 0.11 ENST00000440727.1
ENST00000409240.1
dynactin 1
chr2_+_220306745 0.11 ENST00000431523.1
ENST00000396698.1
ENST00000396695.2
SPEG complex locus
chr3_+_183873240 0.11 ENST00000431765.1
dishevelled segment polarity protein 3
chr16_+_770975 0.11 ENST00000569529.1
ENST00000564000.1
ENST00000219535.3
family with sequence similarity 173, member A
chr21_+_45366811 0.11 ENST00000398058.1
ENST00000457068.1
ENST00000448845.1
1-acylglycerol-3-phosphate O-acyltransferase 3
chr19_+_4343584 0.11 ENST00000596722.1
MPN domain containing
chr5_+_175223313 0.11 ENST00000359546.4
complexin 2
chr9_-_130679257 0.11 ENST00000361444.3
ENST00000335791.5
ENST00000343609.2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr19_+_35629702 0.11 ENST00000351325.4
FXYD domain containing ion transport regulator 1
chr16_+_57653625 0.11 ENST00000567553.1
ENST00000565314.1
G protein-coupled receptor 56
chr12_-_57352103 0.11 ENST00000398138.3
retinol dehydrogenase 16 (all-trans)
chr17_+_7258442 0.11 ENST00000389982.4
ENST00000576060.1
ENST00000330767.4
transmembrane protein 95
chr12_+_6494285 0.10 ENST00000541102.1
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr20_-_3748363 0.10 ENST00000217195.8
chromosome 20 open reading frame 27
chr17_+_55173955 0.10 ENST00000576591.1
A kinase (PRKA) anchor protein 1
chrX_+_153775821 0.10 ENST00000263518.6
ENST00000470142.1
ENST00000393549.2
ENST00000455588.2
ENST00000369602.3
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr3_+_9958758 0.10 ENST00000383812.4
ENST00000438091.1
ENST00000295981.3
ENST00000436503.1
ENST00000403601.3
ENST00000416074.2
ENST00000455057.1
interleukin 17 receptor C
chr1_-_113247543 0.10 ENST00000414971.1
ENST00000534717.1
ras homolog family member C
chr19_-_44031375 0.10 ENST00000292147.2
ethylmalonic encephalopathy 1
chr22_+_29702996 0.10 ENST00000406549.3
ENST00000360113.2
ENST00000341313.6
ENST00000403764.1
ENST00000471961.1
ENST00000407854.1
growth arrest-specific 2 like 1
chr7_-_150777920 0.10 ENST00000353841.2
ENST00000297532.6
Fas-activated serine/threonine kinase
chr2_+_242681835 0.10 ENST00000437164.1
ENST00000454048.1
ENST00000417686.1
D-2-hydroxyglutarate dehydrogenase
chr10_-_28623368 0.10 ENST00000441595.2
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr8_-_145115584 0.10 ENST00000426825.1
5-oxoprolinase (ATP-hydrolysing)
chr1_+_16693578 0.10 ENST00000401088.4
ENST00000471507.1
ENST00000401089.3
ENST00000375590.3
ENST00000492354.1
SUZ RNA binding domain containing 1
chr17_-_7297833 0.10 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3 readthrough (NMD candidate)
chr2_-_3381561 0.10 ENST00000443925.2
ENST00000441271.1
ENST00000444776.1
ENST00000398659.4
ENST00000382125.4
tumor suppressing subtransferable candidate 1
chr16_+_20912382 0.10 ENST00000396052.2
LYR motif containing 1
chrX_+_152907913 0.10 ENST00000370167.4
dual specificity phosphatase 9
chr15_-_74753443 0.10 ENST00000567435.1
ENST00000564488.1
ENST00000565130.1
ENST00000563081.1
ENST00000565335.1
ENST00000395081.2
ENST00000361351.4
ubiquitin-like 7 (bone marrow stromal cell-derived)
chr16_+_85646763 0.10 ENST00000411612.1
ENST00000253458.7
Gse1 coiled-coil protein
chr1_-_21044489 0.10 ENST00000247986.2
kinesin family member 17
chr9_-_35112376 0.10 ENST00000488109.2
family with sequence similarity 214, member B
chr11_-_64901978 0.10 ENST00000294256.8
ENST00000377190.3
synovial apoptosis inhibitor 1, synoviolin
chrX_-_153775760 0.10 ENST00000440967.1
ENST00000393564.2
ENST00000369620.2
glucose-6-phosphate dehydrogenase
chr21_-_18985158 0.09 ENST00000339775.6
BTG family, member 3
chr18_-_14970301 0.09 ENST00000580867.1
RP11-527H14.3
chr5_+_150639360 0.09 ENST00000523004.1
GM2 ganglioside activator
chr11_+_7506713 0.09 ENST00000329293.3
ENST00000534244.1
olfactomedin-like 1
chr14_+_21467414 0.09 ENST00000554422.1
ENST00000298681.4
solute carrier family 39 (zinc transporter), member 2
chr2_-_74780176 0.09 ENST00000409549.1
lysyl oxidase-like 3
chr1_+_215256467 0.09 ENST00000391894.2
ENST00000444842.2
potassium channel, subfamily K, member 2
chr1_-_27286897 0.09 ENST00000320567.5
chromosome 1 open reading frame 172
chr4_+_77177512 0.09 ENST00000606246.1
family with sequence similarity 47, member E
chr15_+_40674963 0.09 ENST00000448395.2
kinetochore-localized astrin/SPAG5 binding protein
chr17_-_39942940 0.09 ENST00000310706.5
ENST00000393931.3
ENST00000424457.1
ENST00000591690.1
junction plakoglobin
chr13_+_78315295 0.09 ENST00000351546.3
SLAIN motif family, member 1
chr17_-_48474828 0.08 ENST00000576448.1
ENST00000225972.7
leucine rich repeat containing 59
chr17_-_57784755 0.08 ENST00000537860.1
ENST00000393038.2
ENST00000409433.2
peptidyl-tRNA hydrolase 2
chr4_+_87856191 0.08 ENST00000503477.1
AF4/FMR2 family, member 1
chrX_-_48980098 0.08 ENST00000156109.5
G patch domain and KOW motifs
chr1_+_228270361 0.08 ENST00000272102.5
ENST00000540651.1
ADP-ribosylation factor 1
chrX_+_135252050 0.08 ENST00000449474.1
ENST00000345434.3
four and a half LIM domains 1
chr16_+_89984287 0.08 ENST00000555147.1
melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
chr14_+_23340822 0.08 ENST00000359591.4
low density lipoprotein receptor-related protein 10
chr5_-_37835929 0.08 ENST00000381826.4
ENST00000427982.1
glial cell derived neurotrophic factor
chr19_+_1407517 0.08 ENST00000336761.6
ENST00000233078.4
DAZ associated protein 1
chr19_+_42772659 0.08 ENST00000572681.2
capicua transcriptional repressor

Network of associatons between targets according to the STRING database.

First level regulatory network of PPARG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.8 GO:1990736 positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.2 0.7 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.2 0.7 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 0.6 GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.1 0.6 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.5 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.8 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.1 0.2 GO:0014028 notochord formation(GO:0014028)
0.1 0.3 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.1 0.4 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 0.2 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 0.2 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.1 0.2 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.2 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.2 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:0045918 negative regulation of cytolysis(GO:0045918) positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.2 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.0 0.2 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.1 GO:0051685 maintenance of ER location(GO:0051685)
0.0 0.4 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.8 GO:0007620 copulation(GO:0007620)
0.0 1.0 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.2 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.2 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.1 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.0 0.3 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.0 0.2 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.2 GO:0032796 uropod organization(GO:0032796)
0.0 0.1 GO:0019516 lactate oxidation(GO:0019516)
0.0 0.2 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.2 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.1 GO:0060584 detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) positive regulation of protein K63-linked ubiquitination(GO:1902523) negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.1 GO:1902824 cleavage furrow ingression(GO:0036090) positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.2 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.1 GO:1901094 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.0 0.1 GO:0031337 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.0 0.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.2 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.2 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.1 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.1 GO:0001300 chronological cell aging(GO:0001300)
0.0 0.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.1 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.1 GO:0033603 postganglionic parasympathetic fiber development(GO:0021784) positive regulation of dopamine secretion(GO:0033603)
0.0 0.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.0 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.0 0.3 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0009730 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.0 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.2 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.3 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.3 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.0 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.2 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 GO:0034706 sodium channel complex(GO:0034706)
0.1 0.2 GO:0036025 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.0 0.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.2 GO:0097513 myosin II filament(GO:0097513)
0.0 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 1.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0033263 CORVET complex(GO:0033263)
0.0 0.1 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.1 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.0 0.1 GO:0072563 endothelial microparticle(GO:0072563)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.0 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.1 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.0 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.1 0.5 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.6 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.2 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.4 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.2 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.1 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.0 0.2 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.8 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.1 GO:0004458 D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.0 1.8 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.1 GO:0047298 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 1.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0004766 spermidine synthase activity(GO:0004766)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.1 GO:0005199 structural constituent of cell wall(GO:0005199)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.0 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.2 GO:0016918 retinal binding(GO:0016918)
0.0 0.1 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.0 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.5 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels