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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for POU2F2_POU3F1

Z-value: 1.21

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Transcription factors associated with POU2F2_POU3F1

Gene Symbol Gene ID Gene Info
POU2F2
ENSG00000028277.16 POU class 2 homeobox 2
POU3F1
ENSG00000185668.5 POU class 3 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU2F2hg19_v2_chr19_-_42636543_426366070.424.1e-01Click!
POU3F1hg19_v2_chr1_-_38512450_38512474-0.069.1e-01Click!

Activity profile of POU2F2_POU3F1 motif

Sorted Z-values of POU2F2_POU3F1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_26251835 2.00 ENST00000356350.2
HIST1H2BH
histone cluster 1, H2bh
chr17_+_38171681 1.90 ENST00000225474.2
ENST00000331769.2
ENST00000394148.3
ENST00000577675.1
CSF3
colony stimulating factor 3 (granulocyte)
chr17_+_38171614 1.71 ENST00000583218.1
ENST00000394149.3
CSF3
colony stimulating factor 3 (granulocyte)
chr2_+_89952792 1.20 ENST00000390265.2
IGKV1D-33
immunoglobulin kappa variable 1D-33
chr1_+_149822620 1.17 ENST00000369159.2
HIST2H2AA4
histone cluster 2, H2aa4
chr9_+_136325089 1.01 ENST00000291722.7
ENST00000316948.4
ENST00000540581.1
CACFD1
calcium channel flower domain containing 1
chr1_-_153044083 0.99 ENST00000341611.2
SPRR2B
small proline-rich protein 2B
chr6_-_27860956 0.97 ENST00000359611.2
HIST1H2AM
histone cluster 1, H2am
chr1_-_149814478 0.92 ENST00000369161.3
HIST2H2AA3
histone cluster 2, H2aa3
chr6_+_27861190 0.85 ENST00000303806.4
HIST1H2BO
histone cluster 1, H2bo
chr6_+_31588478 0.83 ENST00000376007.4
ENST00000376033.2
PRRC2A
proline-rich coiled-coil 2A
chr18_-_61311485 0.83 ENST00000436264.1
ENST00000356424.6
ENST00000341074.5
SERPINB4
serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr19_-_17516449 0.80 ENST00000252593.6
BST2
bone marrow stromal cell antigen 2
chr9_-_35658007 0.76 ENST00000602361.1
RMRP
RNA component of mitochondrial RNA processing endoribonuclease
chr7_-_100183742 0.72 ENST00000310300.6
LRCH4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr12_+_7053172 0.72 ENST00000229281.5
C12orf57
chromosome 12 open reading frame 57
chr6_-_27782548 0.68 ENST00000333151.3
HIST1H2AJ
histone cluster 1, H2aj
chr2_+_90248739 0.63 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chr6_-_26124138 0.61 ENST00000314332.5
ENST00000396984.1
HIST1H2BC
histone cluster 1, H2bc
chr12_+_7052974 0.60 ENST00000544681.1
ENST00000537087.1
C12orf57
chromosome 12 open reading frame 57
chr7_-_27153454 0.59 ENST00000522456.1
HOXA3
homeobox A3
chr7_-_17500294 0.58 ENST00000439046.1
AC019117.2
AC019117.2
chr12_+_122064398 0.58 ENST00000330079.7
ORAI1
ORAI calcium release-activated calcium modulator 1
chr6_+_27775899 0.57 ENST00000358739.3
HIST1H2AI
histone cluster 1, H2ai
chr5_+_159895275 0.55 ENST00000517927.1
MIR146A
microRNA 146a
chr6_-_27100529 0.54 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
HIST1H2BJ
histone cluster 1, H2bj
chr12_-_11175219 0.51 ENST00000390673.2
TAS2R19
taste receptor, type 2, member 19
chr17_-_19651598 0.51 ENST00000570414.1
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr11_-_18258342 0.49 ENST00000278222.4
SAA4
serum amyloid A4, constitutive
chr16_-_74808710 0.49 ENST00000219368.3
ENST00000544337.1
FA2H
fatty acid 2-hydroxylase
chr20_+_33292507 0.48 ENST00000414082.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr12_+_7053228 0.48 ENST00000540506.2
C12orf57
chromosome 12 open reading frame 57
chrX_-_24665353 0.47 ENST00000379144.2
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr1_+_32538520 0.47 ENST00000438825.1
ENST00000456834.2
ENST00000373634.4
ENST00000427288.1
TMEM39B
transmembrane protein 39B
chr19_+_56111680 0.47 ENST00000301073.3
ZNF524
zinc finger protein 524
chr14_-_89960395 0.46 ENST00000555034.1
ENST00000553904.1
FOXN3
forkhead box N3
chr17_+_62461569 0.46 ENST00000603557.1
ENST00000605096.1
MILR1
mast cell immunoglobulin-like receptor 1
chr4_-_108204904 0.45 ENST00000510463.1
DKK2
dickkopf WNT signaling pathway inhibitor 2
chr17_-_47841485 0.44 ENST00000506156.1
ENST00000240364.2
FAM117A
family with sequence similarity 117, member A
chr6_-_27114577 0.42 ENST00000356950.1
ENST00000396891.4
HIST1H2BK
histone cluster 1, H2bk
chr19_-_1132207 0.42 ENST00000438103.2
SBNO2
strawberry notch homolog 2 (Drosophila)
chr12_-_10978957 0.42 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr1_+_32538492 0.42 ENST00000336294.5
TMEM39B
transmembrane protein 39B
chr7_-_41742697 0.41 ENST00000242208.4
INHBA
inhibin, beta A
chr6_-_10415218 0.41 ENST00000466073.1
ENST00000498450.1
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr6_+_26183958 0.41 ENST00000356530.3
HIST1H2BE
histone cluster 1, H2be
chr12_+_113344582 0.41 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr14_+_65007177 0.40 ENST00000247207.6
HSPA2
heat shock 70kDa protein 2
chr12_-_122238464 0.40 ENST00000546227.1
RHOF
ras homolog family member F (in filopodia)
chr12_+_122064673 0.39 ENST00000537188.1
ORAI1
ORAI calcium release-activated calcium modulator 1
chr8_+_102064237 0.38 ENST00000514926.1
RP11-302J23.1
RP11-302J23.1
chr17_+_19091325 0.37 ENST00000584923.1
SNORD3A
small nucleolar RNA, C/D box 3A
chr12_+_132312931 0.37 ENST00000360564.1
ENST00000545671.1
ENST00000545790.1
MMP17
matrix metallopeptidase 17 (membrane-inserted)
chr12_+_14927270 0.36 ENST00000544848.1
H2AFJ
H2A histone family, member J
chr11_+_110225855 0.36 ENST00000526605.1
ENST00000526703.1
RP11-347E10.1
RP11-347E10.1
chr19_+_19144384 0.35 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
ARMC6
armadillo repeat containing 6
chr19_+_3572925 0.35 ENST00000333651.6
ENST00000417382.1
ENST00000453933.1
ENST00000262949.7
HMG20B
high mobility group 20B
chr12_+_113344811 0.34 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr19_+_41305085 0.34 ENST00000303961.4
EGLN2
egl-9 family hypoxia-inducible factor 2
chr2_+_90192768 0.34 ENST00000390275.2
IGKV1D-13
immunoglobulin kappa variable 1D-13
chr19_+_11466062 0.33 ENST00000251473.5
ENST00000591329.1
ENST00000586380.1
DKFZP761J1410
Lipid phosphate phosphatase-related protein type 2
chr5_-_141030943 0.32 ENST00000522783.1
ENST00000519800.1
ENST00000435817.2
FCHSD1
FCH and double SH3 domains 1
chr5_-_88120083 0.32 ENST00000509373.1
MEF2C
myocyte enhancer factor 2C
chr19_+_41305330 0.31 ENST00000593972.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chr6_-_10415470 0.31 ENST00000379604.2
ENST00000379613.3
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr10_+_24528108 0.30 ENST00000438429.1
KIAA1217
KIAA1217
chr19_-_44123734 0.30 ENST00000598676.1
ZNF428
zinc finger protein 428
chr12_-_66275350 0.30 ENST00000536648.1
RP11-366L20.2
Uncharacterized protein
chr8_-_33370607 0.29 ENST00000360742.5
ENST00000523305.1
TTI2
TELO2 interacting protein 2
chr6_+_26217159 0.29 ENST00000303910.2
HIST1H2AE
histone cluster 1, H2ae
chrX_-_55020511 0.29 ENST00000375006.3
ENST00000374992.2
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr19_-_41903161 0.29 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
EXOSC5
exosome component 5
chr3_-_87039662 0.29 ENST00000494229.1
VGLL3
vestigial like 3 (Drosophila)
chr19_-_893200 0.28 ENST00000269814.4
ENST00000395808.3
ENST00000312090.6
ENST00000325464.1
MED16
mediator complex subunit 16
chr19_-_44124019 0.28 ENST00000300811.3
ZNF428
zinc finger protein 428
chr19_+_17858509 0.28 ENST00000594202.1
ENST00000252771.7
ENST00000389133.4
FCHO1
FCH domain only 1
chr17_+_63096903 0.28 ENST00000582940.1
RP11-160O5.1
RP11-160O5.1
chr11_-_62358972 0.27 ENST00000278279.3
TUT1
terminal uridylyl transferase 1, U6 snRNA-specific
chr17_+_40118805 0.26 ENST00000591072.1
ENST00000587679.1
ENST00000393888.1
ENST00000441615.2
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr17_+_40118773 0.26 ENST00000472031.1
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr19_-_19144243 0.26 ENST00000594445.1
ENST00000452918.2
ENST00000600377.1
ENST00000337018.6
SUGP2
SURP and G patch domain containing 2
chr19_+_39903185 0.26 ENST00000409794.3
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr12_-_94673956 0.26 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr1_-_2458026 0.26 ENST00000435556.3
ENST00000378466.3
PANK4
pantothenate kinase 4
chr19_-_50143452 0.25 ENST00000246792.3
RRAS
related RAS viral (r-ras) oncogene homolog
chr19_-_1021113 0.25 ENST00000333175.5
ENST00000356663.3
TMEM259
transmembrane protein 259
chr17_-_7832753 0.25 ENST00000303790.2
KCNAB3
potassium voltage-gated channel, shaker-related subfamily, beta member 3
chr19_-_40791302 0.25 ENST00000392038.2
ENST00000578123.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr1_-_27709793 0.25 ENST00000374027.3
ENST00000374025.3
CD164L2
CD164 sialomucin-like 2
chr1_-_149783914 0.24 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
HIST2H2BF
histone cluster 2, H2bf
chr1_-_209792111 0.24 ENST00000455193.1
LAMB3
laminin, beta 3
chr19_-_44171817 0.24 ENST00000593714.1
PLAUR
plasminogen activator, urokinase receptor
chr15_-_41166414 0.24 ENST00000220507.4
RHOV
ras homolog family member V
chr20_+_33292068 0.23 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr12_-_7245125 0.23 ENST00000542285.1
ENST00000540610.1
C1R
complement component 1, r subcomponent
chr19_-_47164386 0.23 ENST00000391916.2
ENST00000410105.2
DACT3
dishevelled-binding antagonist of beta-catenin 3
chr19_+_19144666 0.23 ENST00000535288.1
ENST00000538663.1
ARMC6
armadillo repeat containing 6
chr19_-_50168962 0.23 ENST00000599223.1
ENST00000593922.1
ENST00000600022.1
ENST00000596765.1
ENST00000599144.1
ENST00000596822.1
ENST00000598108.1
ENST00000601373.1
ENST00000595034.1
ENST00000601291.1
IRF3
interferon regulatory factor 3
chr11_+_64085560 0.22 ENST00000265462.4
ENST00000352435.4
ENST00000347941.4
PRDX5
peroxiredoxin 5
chr1_+_32666188 0.22 ENST00000421922.2
CCDC28B
coiled-coil domain containing 28B
chr17_+_43213004 0.22 ENST00000586346.1
ENST00000398322.3
ENST00000592162.1
ENST00000376955.4
ENST00000321854.8
ACBD4
acyl-CoA binding domain containing 4
chr19_+_11466167 0.22 ENST00000591608.1
DKFZP761J1410
Lipid phosphate phosphatase-related protein type 2
chr17_+_38497640 0.22 ENST00000394086.3
RARA
retinoic acid receptor, alpha
chr17_+_73521763 0.22 ENST00000167462.5
ENST00000375227.4
ENST00000392550.3
ENST00000578363.1
ENST00000579392.1
LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr6_+_43139037 0.21 ENST00000265354.4
SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr8_-_57123815 0.21 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr16_+_4666475 0.21 ENST00000591895.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr5_+_145317356 0.21 ENST00000511217.1
SH3RF2
SH3 domain containing ring finger 2
chr1_+_152975488 0.21 ENST00000542696.1
SPRR3
small proline-rich protein 3
chr19_-_3971050 0.20 ENST00000545797.2
ENST00000596311.1
DAPK3
death-associated protein kinase 3
chr19_+_17516624 0.20 ENST00000596322.1
ENST00000600008.1
ENST00000601885.1
CTD-2521M24.9
CTD-2521M24.9
chr6_-_128222103 0.20 ENST00000434358.1
ENST00000543064.1
ENST00000368248.2
THEMIS
thymocyte selection associated
chr12_+_43086018 0.20 ENST00000550177.1
RP11-25I15.3
RP11-25I15.3
chr16_-_75285762 0.19 ENST00000564028.1
BCAR1
breast cancer anti-estrogen resistance 1
chr3_-_71632894 0.19 ENST00000493089.1
FOXP1
forkhead box P1
chr6_-_11232891 0.19 ENST00000379433.5
ENST00000379446.5
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr1_-_117021430 0.18 ENST00000423907.1
ENST00000434879.1
ENST00000443219.1
RP4-655J12.4
RP4-655J12.4
chr15_+_45406519 0.18 ENST00000323030.5
DUOXA2
dual oxidase maturation factor 2
chr12_+_130646999 0.18 ENST00000539839.1
ENST00000229030.4
FZD10
frizzled family receptor 10
chr22_+_22764088 0.18 ENST00000390299.2
IGLV1-40
immunoglobulin lambda variable 1-40
chr2_+_179318295 0.18 ENST00000442710.1
DFNB59
deafness, autosomal recessive 59
chr12_-_56224546 0.18 ENST00000357606.3
ENST00000547445.1
DNAJC14
DnaJ (Hsp40) homolog, subfamily C, member 14
chr15_+_65337708 0.18 ENST00000334287.2
SLC51B
solute carrier family 51, beta subunit
chr4_-_187517928 0.18 ENST00000512772.1
FAT1
FAT atypical cadherin 1
chr6_+_26273144 0.18 ENST00000377733.2
HIST1H2BI
histone cluster 1, H2bi
chr1_+_156052354 0.18 ENST00000368301.2
LMNA
lamin A/C
chr11_+_537494 0.17 ENST00000270115.7
LRRC56
leucine rich repeat containing 56
chr11_-_62359027 0.17 ENST00000494385.1
ENST00000308436.7
TUT1
terminal uridylyl transferase 1, U6 snRNA-specific
chr19_+_16607122 0.17 ENST00000221671.3
ENST00000594035.1
ENST00000599550.1
ENST00000594813.1
C19orf44
chromosome 19 open reading frame 44
chr5_+_158527630 0.17 ENST00000523301.1
RP11-175K6.1
RP11-175K6.1
chr6_+_34204642 0.17 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr5_-_175965008 0.16 ENST00000537487.1
RNF44
ring finger protein 44
chr11_-_568369 0.16 ENST00000534540.1
ENST00000528245.1
ENST00000500447.1
ENST00000533920.1
MIR210HG
MIR210 host gene (non-protein coding)
chr17_-_19651654 0.16 ENST00000395555.3
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr9_+_35658262 0.16 ENST00000378407.3
ENST00000378406.1
ENST00000426546.2
ENST00000327351.2
ENST00000421582.2
CCDC107
coiled-coil domain containing 107
chr12_-_58212487 0.16 ENST00000549994.1
AVIL
advillin
chr3_-_46068969 0.16 ENST00000542109.1
ENST00000395946.2
XCR1
chemokine (C motif) receptor 1
chr5_-_88120151 0.15 ENST00000506716.1
MEF2C
myocyte enhancer factor 2C
chr11_-_78140882 0.15 ENST00000513207.2
RP11-452H21.4
RP11-452H21.4
chr16_-_75285380 0.15 ENST00000393420.6
ENST00000162330.5
BCAR1
breast cancer anti-estrogen resistance 1
chr19_-_45982076 0.15 ENST00000423698.2
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr2_+_47922958 0.15 ENST00000606499.1
MSH6
mutS homolog 6
chr2_-_61108449 0.15 ENST00000439412.1
ENST00000452343.1
AC010733.4
AC010733.4
chr7_+_16793160 0.14 ENST00000262067.4
TSPAN13
tetraspanin 13
chr19_+_42788172 0.14 ENST00000160740.3
CIC
capicua transcriptional repressor
chr12_+_93096619 0.14 ENST00000397833.3
C12orf74
chromosome 12 open reading frame 74
chr14_+_93389425 0.14 ENST00000216492.5
ENST00000334654.4
CHGA
chromogranin A (parathyroid secretory protein 1)
chr16_+_56691606 0.14 ENST00000334350.6
MT1F
metallothionein 1F
chr15_-_45406348 0.14 ENST00000603300.1
DUOX2
dual oxidase 2
chr2_-_74555350 0.14 ENST00000444570.1
SLC4A5
solute carrier family 4 (sodium bicarbonate cotransporter), member 5
chr17_-_73775839 0.14 ENST00000592643.1
ENST00000591890.1
ENST00000587171.1
ENST00000254810.4
ENST00000589599.1
H3F3B
H3 histone, family 3B (H3.3B)
chr4_+_40194609 0.13 ENST00000508513.1
RHOH
ras homolog family member H
chr4_-_40516560 0.13 ENST00000513473.1
RBM47
RNA binding motif protein 47
chr10_-_29811456 0.13 ENST00000535393.1
SVIL
supervillin
chr3_-_126327398 0.13 ENST00000383572.2
TXNRD3NB
thioredoxin reductase 3 neighbor
chr2_+_68962014 0.13 ENST00000467265.1
ARHGAP25
Rho GTPase activating protein 25
chr6_+_26158343 0.13 ENST00000377777.4
ENST00000289316.2
HIST1H2BD
histone cluster 1, H2bd
chr9_+_136325149 0.13 ENST00000542192.1
CACFD1
calcium channel flower domain containing 1
chr4_-_110223799 0.13 ENST00000399132.1
ENST00000399126.1
ENST00000505591.1
COL25A1
collagen, type XXV, alpha 1
chr19_+_1269324 0.13 ENST00000589710.1
ENST00000588230.1
ENST00000413636.2
ENST00000586472.1
ENST00000589686.1
ENST00000444172.2
ENST00000587323.1
ENST00000320936.5
ENST00000587896.1
ENST00000589235.1
ENST00000591659.1
CIRBP
cold inducible RNA binding protein
chr12_-_51611477 0.13 ENST00000389243.4
POU6F1
POU class 6 homeobox 1
chr21_+_17566643 0.12 ENST00000419952.1
ENST00000445461.2
LINC00478
long intergenic non-protein coding RNA 478
chr19_-_19281054 0.12 ENST00000424583.2
ENST00000410050.1
ENST00000409224.1
ENST00000409447.2
MEF2B
myocyte enhancer factor 2B
chr15_+_67458357 0.12 ENST00000537194.2
SMAD3
SMAD family member 3
chr16_-_30107491 0.12 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
YPEL3
yippee-like 3 (Drosophila)
chr17_-_36358166 0.12 ENST00000537432.1
TBC1D3
TBC1 domain family, member 3
chr12_-_62653903 0.12 ENST00000552075.1
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr6_-_53013620 0.12 ENST00000259803.7
GCM1
glial cells missing homolog 1 (Drosophila)
chr17_+_80858418 0.12 ENST00000574422.1
TBCD
tubulin folding cofactor D
chr2_+_152214098 0.12 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr16_-_19897455 0.12 ENST00000568214.1
ENST00000569479.1
GPRC5B
G protein-coupled receptor, family C, group 5, member B
chr18_-_30716038 0.12 ENST00000581852.1
CCDC178
coiled-coil domain containing 178
chr2_-_214013353 0.12 ENST00000451136.2
ENST00000421754.2
ENST00000374327.4
ENST00000413091.3
IKZF2
IKAROS family zinc finger 2 (Helios)
chr1_-_6052463 0.11 ENST00000378156.4
NPHP4
nephronophthisis 4
chr10_-_103880209 0.11 ENST00000425280.1
LDB1
LIM domain binding 1
chr12_+_93096759 0.11 ENST00000544406.2
C12orf74
chromosome 12 open reading frame 74
chr3_+_50192537 0.11 ENST00000002829.3
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr10_-_98031155 0.11 ENST00000495266.1
BLNK
B-cell linker
chr19_-_40791160 0.11 ENST00000358335.5
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr17_+_40118759 0.11 ENST00000393892.3
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr15_-_45406385 0.11 ENST00000389039.6
DUOX2
dual oxidase 2
chr2_-_225811747 0.11 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr4_+_124320665 0.11 ENST00000394339.2
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr9_+_35658377 0.10 ENST00000378409.3
CCDC107
coiled-coil domain containing 107
chr5_-_2751762 0.10 ENST00000302057.5
ENST00000382611.6
IRX2
iroquois homeobox 2
chr12_+_19358192 0.10 ENST00000538305.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chrX_-_154688276 0.10 ENST00000369445.2
F8A3
coagulation factor VIII-associated 3
chr2_+_207804278 0.10 ENST00000272852.3
CPO
carboxypeptidase O
chr3_+_124303539 0.10 ENST00000428018.2
KALRN
kalirin, RhoGEF kinase
chr22_+_38093005 0.10 ENST00000406386.3
TRIOBP
TRIO and F-actin binding protein
chr12_-_7245080 0.10 ENST00000541042.1
ENST00000540242.1
C1R
complement component 1, r subcomponent
chr17_-_7307358 0.10 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
TMEM256
TMEM256-PLSCR3
transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chr12_+_72080253 0.10 ENST00000549735.1
TMEM19
transmembrane protein 19
chr2_-_166930131 0.10 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr19_-_47291843 0.10 ENST00000542575.2
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr3_-_87040259 0.10 ENST00000383698.3
VGLL3
vestigial like 3 (Drosophila)
chr3_-_192445289 0.10 ENST00000430714.1
ENST00000418610.1
ENST00000448795.1
ENST00000445105.2
FGF12
fibroblast growth factor 12
chr18_-_53089538 0.10 ENST00000566777.1
TCF4
transcription factor 4
chr3_+_187957646 0.10 ENST00000457242.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr16_-_73082274 0.10 ENST00000268489.5
ZFHX3
zinc finger homeobox 3

Network of associatons between targets according to the STRING database.

First level regulatory network of POU2F2_POU3F1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0036343 psychomotor behavior(GO:0036343)
0.3 3.6 GO:0030223 neutrophil differentiation(GO:0030223)
0.3 0.8 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.3 0.8 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731)
0.1 0.7 GO:0021623 optic cup structural organization(GO:0003409) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.1 0.4 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 0.4 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 1.3 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.6 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.2 GO:0061145 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145)
0.1 0.5 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.3 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.4 GO:0071486 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.1 GO:1900738 dense core granule biogenesis(GO:0061110) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) positive regulation of relaxation of muscle(GO:1901079) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.0 1.0 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.5 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.5 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 0.5 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.3 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.8 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 1.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0042335 cuticle development(GO:0042335) hypophysis morphogenesis(GO:0048850)
0.0 0.4 GO:0042756 drinking behavior(GO:0042756)
0.0 0.1 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.0 GO:1900200 mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212)
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.3 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.2 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.2 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.2 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.5 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:1900005 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957) positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.2 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.4 GO:0035290 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.0 0.2 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.0 0.1 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.4 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.1 GO:0061054 negative regulation of mesodermal cell fate specification(GO:0042662) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.0 0.0 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.4 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 1.2 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.5 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 3.0 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.1 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 1.3 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0035547 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.0 GO:1905069 allantois development(GO:1905069)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.1 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.1 GO:0061373 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.1 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.2 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.0 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.2 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.2 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 0.2 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.3 GO:0035729 cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.0 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.2 GO:0031033 myosin filament organization(GO:0031033)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 4.5 GO:0000786 nucleosome(GO:0000786)
0.0 0.6 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.4 GO:0036128 CatSper complex(GO:0036128) meiotic spindle(GO:0072687)
0.0 0.1 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 1.3 GO:0001533 cornified envelope(GO:0001533)
0.0 0.6 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.1 0.5 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 1.0 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.4 GO:0034711 inhibin binding(GO:0034711)
0.1 0.4 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 1.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.3 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.7 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.7 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 1.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.6 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.2 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 0.1 GO:0032143 single thymine insertion binding(GO:0032143)
0.0 0.1 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.5 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.2 GO:0001016 RNA polymerase III regulatory region DNA binding(GO:0001016) thioredoxin peroxidase activity(GO:0008379)
0.0 0.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.4 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 3.4 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 0.4 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.0 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 1.3 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 4.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.4 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism