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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PKNOX2

Z-value: 0.76

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Transcription factors associated with PKNOX2

Gene Symbol Gene ID Gene Info
PKNOX2
ENSG00000165495.11 PBX/knotted 1 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PKNOX2hg19_v2_chr11_+_125034586_1250346040.651.6e-01Click!

Activity profile of PKNOX2 motif

Sorted Z-values of PKNOX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_99837856 0.27 ENST00000518165.1
ENST00000419617.2
STK3
serine/threonine kinase 3
chr2_+_113321939 0.26 ENST00000458012.2
POLR1B
polymerase (RNA) I polypeptide B, 128kDa
chr5_+_72509751 0.25 ENST00000515556.1
ENST00000513379.1
ENST00000427584.2
RP11-60A8.1
RP11-60A8.1
chr16_+_2880157 0.24 ENST00000382280.3
ZG16B
zymogen granule protein 16B
chr19_+_41281060 0.23 ENST00000594436.1
ENST00000597784.1
MIA
melanoma inhibitory activity
chr18_+_3449330 0.22 ENST00000549253.1
TGIF1
TGFB-induced factor homeobox 1
chr15_+_96904487 0.22 ENST00000600790.1
AC087477.1
Uncharacterized protein
chr19_+_57050317 0.22 ENST00000301318.3
ENST00000591844.1
ZFP28
ZFP28 zinc finger protein
chr13_+_20268547 0.22 ENST00000601204.1
AL354808.2
AL354808.2
chr10_+_94608218 0.22 ENST00000371543.1
EXOC6
exocyst complex component 6
chr6_+_17600576 0.21 ENST00000259963.3
FAM8A1
family with sequence similarity 8, member A1
chr2_-_202316169 0.20 ENST00000430254.1
TRAK2
trafficking protein, kinesin binding 2
chr12_+_113495492 0.20 ENST00000257600.3
DTX1
deltex homolog 1 (Drosophila)
chr3_-_52719888 0.19 ENST00000458294.1
PBRM1
polybromo 1
chr5_-_132073111 0.19 ENST00000403231.1
KIF3A
kinesin family member 3A
chr18_-_52626622 0.18 ENST00000591504.1
CCDC68
coiled-coil domain containing 68
chr16_+_2880369 0.18 ENST00000572863.1
ZG16B
zymogen granule protein 16B
chr11_+_74660278 0.18 ENST00000263672.6
ENST00000530257.1
ENST00000526361.1
ENST00000532972.1
SPCS2
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr22_-_31885514 0.18 ENST00000397525.1
EIF4ENIF1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr19_+_41281282 0.17 ENST00000263369.3
MIA
melanoma inhibitory activity
chr2_+_202316392 0.16 ENST00000194530.3
ENST00000392249.2
STRADB
STE20-related kinase adaptor beta
chr6_+_111195973 0.16 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
AMD1
adenosylmethionine decarboxylase 1
chr9_-_123639304 0.16 ENST00000436309.1
PHF19
PHD finger protein 19
chr14_+_61995722 0.16 ENST00000556347.1
RP11-47I22.4
RP11-47I22.4
chr5_-_81046841 0.16 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
SSBP2
single-stranded DNA binding protein 2
chr4_-_157892167 0.16 ENST00000541126.1
PDGFC
platelet derived growth factor C
chr3_+_52719936 0.15 ENST00000418458.1
ENST00000394799.2
GNL3
guanine nucleotide binding protein-like 3 (nucleolar)
chr2_+_196440692 0.15 ENST00000458054.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr13_-_48575376 0.15 ENST00000434484.1
SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chr17_-_29151794 0.15 ENST00000324238.6
CRLF3
cytokine receptor-like factor 3
chr8_+_57124245 0.15 ENST00000521831.1
ENST00000355315.3
ENST00000303759.3
ENST00000517636.1
ENST00000517933.1
ENST00000518801.1
ENST00000523975.1
ENST00000396723.5
ENST00000523061.1
ENST00000521524.1
CHCHD7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr3_-_101395936 0.15 ENST00000461821.1
ZBTB11
zinc finger and BTB domain containing 11
chr4_-_157892055 0.15 ENST00000422544.2
PDGFC
platelet derived growth factor C
chr6_+_41021027 0.15 ENST00000244669.2
APOBEC2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr5_-_139283982 0.14 ENST00000340391.3
NRG2
neuregulin 2
chr3_+_186692745 0.14 ENST00000438590.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr9_+_6758109 0.14 ENST00000536108.1
KDM4C
lysine (K)-specific demethylase 4C
chr8_+_11666649 0.13 ENST00000528643.1
ENST00000525777.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr11_-_111741994 0.13 ENST00000398006.2
ALG9
ALG9, alpha-1,2-mannosyltransferase
chr2_+_191208196 0.13 ENST00000392329.2
ENST00000322522.4
ENST00000430311.1
ENST00000541441.1
INPP1
inositol polyphosphate-1-phosphatase
chr5_+_125758865 0.13 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr17_-_29151686 0.13 ENST00000544695.1
CRLF3
cytokine receptor-like factor 3
chr6_+_150070831 0.13 ENST00000367380.5
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr16_-_1275257 0.12 ENST00000234798.4
TPSG1
tryptase gamma 1
chr15_+_68346501 0.12 ENST00000249636.6
PIAS1
protein inhibitor of activated STAT, 1
chr17_-_27405875 0.12 ENST00000359450.6
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr12_+_62654155 0.11 ENST00000312635.6
ENST00000393654.3
ENST00000549237.1
USP15
ubiquitin specific peptidase 15
chr10_+_28822636 0.11 ENST00000442148.1
ENST00000448193.1
WAC
WW domain containing adaptor with coiled-coil
chr5_+_125758813 0.11 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr17_+_8316442 0.11 ENST00000582812.1
NDEL1
nudE neurodevelopment protein 1-like 1
chr2_+_64681219 0.11 ENST00000238875.5
LGALSL
lectin, galactoside-binding-like
chr2_-_242842587 0.11 ENST00000404031.1
AC131097.4
Protein LOC285095
chr3_-_33481835 0.11 ENST00000283629.3
UBP1
upstream binding protein 1 (LBP-1a)
chr14_-_54421190 0.11 ENST00000417573.1
BMP4
bone morphogenetic protein 4
chr6_-_101329191 0.10 ENST00000324723.6
ENST00000369162.2
ENST00000522650.1
ASCC3
activating signal cointegrator 1 complex subunit 3
chr2_+_191208601 0.10 ENST00000413239.1
ENST00000431594.1
ENST00000444194.1
INPP1
inositol polyphosphate-1-phosphatase
chr6_-_101329157 0.10 ENST00000369143.2
ASCC3
activating signal cointegrator 1 complex subunit 3
chr6_+_150070857 0.10 ENST00000544496.1
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chrX_-_80377162 0.10 ENST00000430960.1
ENST00000447319.1
HMGN5
high mobility group nucleosome binding domain 5
chr6_+_138188378 0.09 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr18_-_67872891 0.09 ENST00000454359.1
ENST00000437017.1
RTTN
rotatin
chr16_+_2880254 0.09 ENST00000570670.1
ZG16B
zymogen granule protein 16B
chr15_+_59908633 0.09 ENST00000559626.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr18_-_54318353 0.09 ENST00000590954.1
ENST00000540155.1
TXNL1
thioredoxin-like 1
chr3_+_113667354 0.09 ENST00000491556.1
ZDHHC23
zinc finger, DHHC-type containing 23
chrX_-_128788914 0.09 ENST00000429967.1
ENST00000307484.6
APLN
apelin
chr3_-_52719810 0.09 ENST00000424867.1
ENST00000394830.3
ENST00000431678.1
ENST00000450271.1
PBRM1
polybromo 1
chr9_-_99637820 0.08 ENST00000289032.8
ENST00000535338.1
ZNF782
zinc finger protein 782
chr3_-_33482002 0.08 ENST00000283628.5
ENST00000456378.1
UBP1
upstream binding protein 1 (LBP-1a)
chrX_+_16804544 0.08 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chr22_+_17082732 0.08 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
TPTEP1
transmembrane phosphatase with tensin homology pseudogene 1
chr14_+_24600484 0.08 ENST00000267426.5
FITM1
fat storage-inducing transmembrane protein 1
chr18_-_54305658 0.08 ENST00000586262.1
ENST00000217515.6
TXNL1
thioredoxin-like 1
chr2_+_64681103 0.08 ENST00000464281.1
LGALSL
lectin, galactoside-binding-like
chr9_+_125027127 0.08 ENST00000441707.1
ENST00000373723.5
ENST00000373729.1
MRRF
mitochondrial ribosome recycling factor
chr4_-_157892498 0.08 ENST00000502773.1
PDGFC
platelet derived growth factor C
chr9_-_132805430 0.08 ENST00000446176.2
ENST00000355681.3
ENST00000420781.1
FNBP1
formin binding protein 1
chr5_-_81046904 0.08 ENST00000515395.1
SSBP2
single-stranded DNA binding protein 2
chr5_-_81046922 0.07 ENST00000514493.1
ENST00000320672.4
SSBP2
single-stranded DNA binding protein 2
chr9_+_133454943 0.07 ENST00000319725.9
FUBP3
far upstream element (FUSE) binding protein 3
chr12_+_69201923 0.07 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr6_+_37225540 0.07 ENST00000373491.3
TBC1D22B
TBC1 domain family, member 22B
chr11_-_132813627 0.07 ENST00000374778.4
OPCML
opioid binding protein/cell adhesion molecule-like
chr20_+_43514320 0.07 ENST00000372839.3
ENST00000428262.1
ENST00000445830.1
YWHAB
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
chrX_-_80377118 0.07 ENST00000373250.3
HMGN5
high mobility group nucleosome binding domain 5
chr2_-_202316260 0.07 ENST00000332624.3
TRAK2
trafficking protein, kinesin binding 2
chr3_+_32147997 0.07 ENST00000282541.5
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr11_-_46867780 0.07 ENST00000529230.1
ENST00000415402.1
ENST00000312055.5
CKAP5
cytoskeleton associated protein 5
chr2_-_18770812 0.06 ENST00000359846.2
ENST00000304081.4
ENST00000600945.1
ENST00000532967.1
ENST00000444297.2
NT5C1B
NT5C1B-RDH14
5'-nucleotidase, cytosolic IB
NT5C1B-RDH14 readthrough
chr8_+_133787586 0.06 ENST00000395379.1
ENST00000395386.2
ENST00000337920.4
PHF20L1
PHD finger protein 20-like 1
chr18_+_3449821 0.06 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1
TGFB-induced factor homeobox 1
chr6_-_37225391 0.06 ENST00000356757.2
TMEM217
transmembrane protein 217
chr11_-_71810258 0.06 ENST00000544594.1
LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr5_+_118406796 0.06 ENST00000503802.1
DMXL1
Dmx-like 1
chr4_-_83483094 0.06 ENST00000508701.1
ENST00000454948.3
TMEM150C
transmembrane protein 150C
chr2_-_190446738 0.06 ENST00000427419.1
ENST00000455320.1
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr16_+_57481382 0.06 ENST00000564655.1
ENST00000567072.1
ENST00000567933.1
ENST00000563166.1
COQ9
coenzyme Q9
chr1_-_179112189 0.06 ENST00000512653.1
ENST00000344730.3
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr16_-_57481278 0.06 ENST00000567751.1
ENST00000568940.1
ENST00000563341.1
ENST00000565961.1
ENST00000569370.1
ENST00000567518.1
ENST00000565786.1
ENST00000394391.4
CIAPIN1
cytokine induced apoptosis inhibitor 1
chr9_+_6758024 0.05 ENST00000442236.2
KDM4C
lysine (K)-specific demethylase 4C
chr11_-_119247004 0.05 ENST00000531070.1
USP2
ubiquitin specific peptidase 2
chr1_+_66258846 0.05 ENST00000341517.4
PDE4B
phosphodiesterase 4B, cAMP-specific
chr18_+_3450161 0.05 ENST00000551402.1
ENST00000577543.1
TGIF1
TGFB-induced factor homeobox 1
chr1_-_35658736 0.05 ENST00000357214.5
SFPQ
splicing factor proline/glutamine-rich
chr1_+_110577229 0.05 ENST00000369795.3
ENST00000369794.2
STRIP1
striatin interacting protein 1
chr16_-_30457048 0.05 ENST00000500504.2
ENST00000542752.1
SEPHS2
selenophosphate synthetase 2
chr18_+_54318616 0.05 ENST00000254442.3
WDR7
WD repeat domain 7
chr10_+_70661014 0.05 ENST00000373585.3
DDX50
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr8_+_72755796 0.05 ENST00000524152.1
RP11-383H13.1
Protein LOC100132891; cDNA FLJ53548
chr12_+_62654119 0.05 ENST00000353364.3
ENST00000549523.1
ENST00000280377.5
USP15
ubiquitin specific peptidase 15
chr2_-_61765732 0.05 ENST00000443240.1
ENST00000436018.1
XPO1
exportin 1 (CRM1 homolog, yeast)
chr11_+_120207787 0.05 ENST00000397843.2
ENST00000356641.3
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr1_+_113263199 0.05 ENST00000361886.3
FAM19A3
family with sequence similarity 19 (chemokine (C-C motif)-like), member A3
chr16_+_2880296 0.05 ENST00000571723.1
ZG16B
zymogen granule protein 16B
chr14_-_21994337 0.05 ENST00000537235.1
ENST00000450879.2
SALL2
spalt-like transcription factor 2
chrX_-_77225135 0.05 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr19_+_41281416 0.04 ENST00000597140.1
MIA
melanoma inhibitory activity
chr9_-_123639600 0.04 ENST00000373896.3
PHF19
PHD finger protein 19
chr5_+_118407053 0.04 ENST00000311085.8
ENST00000539542.1
DMXL1
Dmx-like 1
chr7_-_156803329 0.04 ENST00000252971.6
MNX1
motor neuron and pancreas homeobox 1
chr4_+_169418255 0.04 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr17_-_40337470 0.04 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr2_-_61765315 0.04 ENST00000406957.1
ENST00000401558.2
XPO1
exportin 1 (CRM1 homolog, yeast)
chr21_-_32931290 0.04 ENST00000286827.3
TIAM1
T-cell lymphoma invasion and metastasis 1
chr3_+_185080908 0.04 ENST00000265026.3
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr1_-_201081579 0.04 ENST00000367338.3
ENST00000362061.3
CACNA1S
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr2_+_219524473 0.04 ENST00000439945.1
ENST00000431802.1
BCS1L
BC1 (ubiquinol-cytochrome c reductase) synthesis-like
chr11_-_132812987 0.04 ENST00000541867.1
OPCML
opioid binding protein/cell adhesion molecule-like
chr1_+_161736072 0.04 ENST00000367942.3
ATF6
activating transcription factor 6
chr8_-_37594944 0.04 ENST00000330539.1
RP11-863K10.7
Uncharacterized protein
chr8_-_20161466 0.03 ENST00000381569.1
LZTS1
leucine zipper, putative tumor suppressor 1
chr4_-_46391367 0.03 ENST00000503806.1
ENST00000356504.1
ENST00000514090.1
ENST00000506961.1
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr15_-_37392086 0.03 ENST00000561208.1
MEIS2
Meis homeobox 2
chr17_-_35969409 0.03 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
SYNRG
synergin, gamma
chr5_-_52405564 0.03 ENST00000510818.2
ENST00000396954.3
ENST00000508922.1
ENST00000361377.4
ENST00000582677.1
ENST00000584946.1
ENST00000450852.3
MOCS2
molybdenum cofactor synthesis 2
chr2_-_74780176 0.03 ENST00000409549.1
LOXL3
lysyl oxidase-like 3
chr3_+_183899770 0.03 ENST00000442686.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr4_+_128703295 0.03 ENST00000296464.4
ENST00000508549.1
HSPA4L
heat shock 70kDa protein 4-like
chr5_-_94620239 0.03 ENST00000515393.1
MCTP1
multiple C2 domains, transmembrane 1
chr10_+_49514698 0.03 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
MAPK8
mitogen-activated protein kinase 8
chr3_-_52719912 0.03 ENST00000420148.1
PBRM1
polybromo 1
chr11_+_129245796 0.02 ENST00000281437.4
BARX2
BARX homeobox 2
chr10_-_101945771 0.02 ENST00000370408.2
ENST00000407654.3
ERLIN1
ER lipid raft associated 1
chr4_+_3076388 0.02 ENST00000355072.5
HTT
huntingtin
chr3_+_23244780 0.02 ENST00000396703.1
UBE2E2
ubiquitin-conjugating enzyme E2E 2
chr10_+_51565188 0.02 ENST00000430396.2
ENST00000374087.4
ENST00000414907.2
NCOA4
nuclear receptor coactivator 4
chr7_-_148580563 0.02 ENST00000476773.1
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr4_+_140222609 0.02 ENST00000296543.5
ENST00000398947.1
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr9_+_87285539 0.02 ENST00000359847.3
NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr8_+_31496809 0.02 ENST00000518104.1
ENST00000519301.1
NRG1
neuregulin 1
chr1_-_234667504 0.02 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
RP5-855F14.1
chr10_-_124768300 0.01 ENST00000368886.5
IKZF5
IKAROS family zinc finger 5 (Pegasus)
chr7_-_104909435 0.01 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr2_+_128848740 0.01 ENST00000375990.3
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr16_+_57481349 0.01 ENST00000262507.6
ENST00000565964.1
COQ9
coenzyme Q9
chr5_+_125759140 0.01 ENST00000543198.1
GRAMD3
GRAM domain containing 3
chr17_-_26220366 0.01 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYRM9
RP1-66C13.4
LYR motif containing 9
Uncharacterized protein
chr2_+_113033164 0.01 ENST00000409871.1
ENST00000343936.4
ZC3H6
zinc finger CCCH-type containing 6
chr4_+_166300084 0.01 ENST00000402744.4
CPE
carboxypeptidase E
chr11_-_59383617 0.01 ENST00000263847.1
OSBP
oxysterol binding protein
chr9_+_128510454 0.01 ENST00000491787.3
ENST00000447726.2
PBX3
pre-B-cell leukemia homeobox 3
chr2_+_128848881 0.01 ENST00000259253.6
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr12_+_49621658 0.01 ENST00000541364.1
TUBA1C
tubulin, alpha 1c
chr4_-_184241927 0.01 ENST00000323319.5
CLDN22
claudin 22
chr18_+_54318566 0.00 ENST00000589935.1
ENST00000357574.3
WDR7
WD repeat domain 7
chr6_+_42123141 0.00 ENST00000418175.1
ENST00000541991.1
ENST00000053469.4
ENST00000394237.1
ENST00000372963.1
GUCA1A
RP1-139D8.6
guanylate cyclase activator 1A (retina)
RP1-139D8.6
chr1_-_100598444 0.00 ENST00000535161.1
ENST00000287482.5
SASS6
spindle assembly 6 homolog (C. elegans)
chr11_-_8832521 0.00 ENST00000530438.1
ST5
suppression of tumorigenicity 5
chr4_-_149365827 0.00 ENST00000344721.4
NR3C2
nuclear receptor subfamily 3, group C, member 2
chr22_+_30279144 0.00 ENST00000401950.2
ENST00000333027.3
ENST00000445401.1
ENST00000323630.5
ENST00000351488.3
MTMR3
myotubularin related protein 3
chr16_+_50776021 0.00 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
CYLD
cylindromatosis (turban tumor syndrome)
chr9_-_73477826 0.00 ENST00000396285.1
ENST00000396292.4
ENST00000396280.5
ENST00000358082.3
ENST00000408909.2
ENST00000377097.3
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chrX_+_2924654 0.00 ENST00000381130.2
ARSH
arylsulfatase family, member H
chr2_-_219524193 0.00 ENST00000450560.1
ENST00000449707.1
ENST00000432460.1
ENST00000411696.2
ZNF142
zinc finger protein 142

Network of associatons between targets according to the STRING database.

First level regulatory network of PKNOX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.0 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.2 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.0 0.2 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.1 GO:0051466 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466) regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.1 GO:0034148 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of osteoclast proliferation(GO:0090291) negative regulation of CD40 signaling pathway(GO:2000349)
0.0 0.1 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.1 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 0.1 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.0 0.3 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0072192 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.1 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.4 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.1 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.1 GO:0070839 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
0.0 0.3 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.0 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.0 GO:1903979 negative regulation of microglial cell activation(GO:1903979)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.0 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.0 GO:0019008 molybdopterin synthase complex(GO:0019008)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0019808 polyamine binding(GO:0019808)
0.0 0.2 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.1 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.1 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 0.1 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.2 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.0 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.0 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)