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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PKNOX1_TGIF2

Z-value: 0.74

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Transcription factors associated with PKNOX1_TGIF2

Gene Symbol Gene ID Gene Info
PKNOX1
ENSG00000160199.10 PBX/knotted 1 homeobox 1
TGIF2
ENSG00000118707.5 TGFB induced factor homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TGIF2hg19_v2_chr20_+_35202909_35203075-0.853.3e-02Click!
PKNOX1hg19_v2_chr21_+_44394620_443947370.236.7e-01Click!

Activity profile of PKNOX1_TGIF2 motif

Sorted Z-values of PKNOX1_TGIF2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_191208601 0.82 ENST00000413239.1
ENST00000431594.1
ENST00000444194.1
INPP1
inositol polyphosphate-1-phosphatase
chr1_-_63988846 0.60 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
ITGB3BP
integrin beta 3 binding protein (beta3-endonexin)
chr18_-_54318353 0.53 ENST00000590954.1
ENST00000540155.1
TXNL1
thioredoxin-like 1
chr9_-_33447584 0.52 ENST00000297991.4
AQP3
aquaporin 3 (Gill blood group)
chr4_-_175443484 0.52 ENST00000514584.1
ENST00000542498.1
ENST00000296521.7
ENST00000422112.2
ENST00000504433.1
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr15_+_96904487 0.50 ENST00000600790.1
AC087477.1
Uncharacterized protein
chr1_+_63989004 0.48 ENST00000371088.4
EFCAB7
EF-hand calcium binding domain 7
chr5_+_150406527 0.47 ENST00000520059.1
GPX3
glutathione peroxidase 3 (plasma)
chr4_-_175443943 0.45 ENST00000296522.6
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr7_+_79765071 0.41 ENST00000457358.2
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr16_-_79634595 0.41 ENST00000326043.4
ENST00000393350.1
MAF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr2_+_29353520 0.39 ENST00000438819.1
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr3_+_186692745 0.38 ENST00000438590.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr6_+_26124373 0.37 ENST00000377791.2
ENST00000602637.1
HIST1H2AC
histone cluster 1, H2ac
chr17_-_77967433 0.35 ENST00000571872.1
TBC1D16
TBC1 domain family, member 16
chr8_-_99837856 0.34 ENST00000518165.1
ENST00000419617.2
STK3
serine/threonine kinase 3
chr19_+_39759154 0.34 ENST00000331982.5
IFNL2
interferon, lambda 2
chr22_+_20905422 0.31 ENST00000424287.1
ENST00000423862.1
MED15
mediator complex subunit 15
chr7_+_142448053 0.28 ENST00000422143.2
TRBV29-1
T cell receptor beta variable 29-1
chr2_-_192015697 0.27 ENST00000409995.1
STAT4
signal transducer and activator of transcription 4
chr1_-_145715565 0.26 ENST00000369288.2
ENST00000369290.1
ENST00000401557.3
CD160
CD160 molecule
chr18_+_3449330 0.25 ENST00000549253.1
TGIF1
TGFB-induced factor homeobox 1
chr11_+_827553 0.24 ENST00000528542.2
ENST00000450448.1
EFCAB4A
EF-hand calcium binding domain 4A
chr12_+_69004619 0.24 ENST00000250559.9
ENST00000393436.5
ENST00000425247.2
ENST00000489473.2
ENST00000422358.2
ENST00000541167.1
ENST00000538283.1
ENST00000341355.5
ENST00000537460.1
ENST00000450214.2
ENST00000545270.1
ENST00000538980.1
ENST00000542018.1
ENST00000543393.1
RAP1B
RAP1B, member of RAS oncogene family
chr18_-_54305658 0.23 ENST00000586262.1
ENST00000217515.6
TXNL1
thioredoxin-like 1
chr1_-_32384693 0.23 ENST00000602683.1
ENST00000470404.1
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr1_-_70671216 0.22 ENST00000370952.3
LRRC40
leucine rich repeat containing 40
chr2_+_191208656 0.22 ENST00000458647.1
INPP1
inositol polyphosphate-1-phosphatase
chr4_-_83483094 0.22 ENST00000508701.1
ENST00000454948.3
TMEM150C
transmembrane protein 150C
chr6_-_41673552 0.22 ENST00000419574.1
ENST00000445214.1
TFEB
transcription factor EB
chr7_+_23637118 0.21 ENST00000448353.1
CCDC126
coiled-coil domain containing 126
chr9_-_99180597 0.21 ENST00000375256.4
ZNF367
zinc finger protein 367
chr2_-_61765315 0.21 ENST00000406957.1
ENST00000401558.2
XPO1
exportin 1 (CRM1 homolog, yeast)
chr3_+_38017264 0.21 ENST00000436654.1
CTDSPL
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr4_+_166300084 0.20 ENST00000402744.4
CPE
carboxypeptidase E
chr18_-_52626622 0.20 ENST00000591504.1
CCDC68
coiled-coil domain containing 68
chr16_-_30457048 0.19 ENST00000500504.2
ENST00000542752.1
SEPHS2
selenophosphate synthetase 2
chr2_+_191208791 0.19 ENST00000423767.1
ENST00000451089.1
INPP1
inositol polyphosphate-1-phosphatase
chr14_+_61995722 0.19 ENST00000556347.1
RP11-47I22.4
RP11-47I22.4
chr2_+_223725723 0.19 ENST00000535678.1
ACSL3
acyl-CoA synthetase long-chain family member 3
chr5_-_42887494 0.19 ENST00000514218.1
SEPP1
selenoprotein P, plasma, 1
chr1_-_205391178 0.19 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1
LEM domain containing 1
chr18_+_54318893 0.19 ENST00000593058.1
WDR7
WD repeat domain 7
chr22_+_20905269 0.19 ENST00000457322.1
MED15
mediator complex subunit 15
chr5_-_55008072 0.19 ENST00000512208.1
SLC38A9
solute carrier family 38, member 9
chr9_-_134615326 0.18 ENST00000438647.1
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr6_-_35656685 0.18 ENST00000539068.1
ENST00000540787.1
FKBP5
FK506 binding protein 5
chr7_+_23637763 0.18 ENST00000410069.1
CCDC126
coiled-coil domain containing 126
chr6_+_111195973 0.18 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
AMD1
adenosylmethionine decarboxylase 1
chr15_+_51200871 0.17 ENST00000560508.1
AP4E1
adaptor-related protein complex 4, epsilon 1 subunit
chr2_-_190446738 0.17 ENST00000427419.1
ENST00000455320.1
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr7_+_39605966 0.17 ENST00000223273.2
ENST00000448268.1
ENST00000432096.2
YAE1D1
Yae1 domain containing 1
chr9_-_100459639 0.17 ENST00000375128.4
XPA
xeroderma pigmentosum, complementation group A
chr17_+_26833250 0.17 ENST00000577936.1
ENST00000579795.1
FOXN1
forkhead box N1
chr13_+_20268547 0.17 ENST00000601204.1
AL354808.2
AL354808.2
chr2_-_102003987 0.16 ENST00000324768.5
CREG2
cellular repressor of E1A-stimulated genes 2
chr5_+_43603229 0.16 ENST00000344920.4
ENST00000512996.2
NNT
nicotinamide nucleotide transhydrogenase
chr13_-_41837620 0.16 ENST00000379477.1
ENST00000452359.1
ENST00000379480.4
ENST00000430347.2
MTRF1
mitochondrial translational release factor 1
chr8_-_17555164 0.16 ENST00000297488.6
MTUS1
microtubule associated tumor suppressor 1
chr5_-_132073111 0.16 ENST00000403231.1
KIF3A
kinesin family member 3A
chr10_-_118764862 0.16 ENST00000260777.10
KIAA1598
KIAA1598
chr1_-_247171347 0.16 ENST00000339986.7
ENST00000487338.2
ZNF695
zinc finger protein 695
chr3_-_142166904 0.16 ENST00000264951.4
XRN1
5'-3' exoribonuclease 1
chr12_+_69201923 0.15 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr11_-_1782625 0.15 ENST00000438213.1
CTSD
cathepsin D
chr6_+_53794780 0.15 ENST00000505762.1
ENST00000511369.1
ENST00000431554.2
MLIP
RP11-411K7.1
muscular LMNA-interacting protein
RP11-411K7.1
chr2_+_10560147 0.15 ENST00000422133.1
HPCAL1
hippocalcin-like 1
chr8_+_97657449 0.15 ENST00000220763.5
CPQ
carboxypeptidase Q
chr14_+_101295948 0.15 ENST00000452514.2
MEG3
maternally expressed 3 (non-protein coding)
chr19_+_11877838 0.15 ENST00000357901.4
ENST00000454339.2
ZNF441
zinc finger protein 441
chr10_-_4720333 0.15 ENST00000430998.2
LINC00704
long intergenic non-protein coding RNA 704
chr3_-_142166796 0.15 ENST00000392981.2
XRN1
5'-3' exoribonuclease 1
chr4_+_128886584 0.15 ENST00000513371.1
C4orf29
chromosome 4 open reading frame 29
chr11_+_27062272 0.15 ENST00000529202.1
ENST00000533566.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr4_-_47839966 0.14 ENST00000273857.4
ENST00000505909.1
ENST00000502252.1
CORIN
corin, serine peptidase
chr2_+_198380289 0.14 ENST00000233892.4
ENST00000409916.1
MOB4
MOB family member 4, phocein
chr11_+_6411636 0.14 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
SMPD1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr4_+_86396321 0.14 ENST00000503995.1
ARHGAP24
Rho GTPase activating protein 24
chr10_+_94608245 0.14 ENST00000443748.2
ENST00000260762.6
EXOC6
exocyst complex component 6
chr2_+_191208196 0.14 ENST00000392329.2
ENST00000322522.4
ENST00000430311.1
ENST00000541441.1
INPP1
inositol polyphosphate-1-phosphatase
chr2_-_61765732 0.14 ENST00000443240.1
ENST00000436018.1
XPO1
exportin 1 (CRM1 homolog, yeast)
chr6_-_101329191 0.14 ENST00000324723.6
ENST00000369162.2
ENST00000522650.1
ASCC3
activating signal cointegrator 1 complex subunit 3
chr3_-_3221358 0.14 ENST00000424814.1
ENST00000450014.1
ENST00000231948.4
ENST00000432408.2
CRBN
cereblon
chr20_-_36156264 0.14 ENST00000445723.1
ENST00000414080.1
BLCAP
bladder cancer associated protein
chr3_-_149093499 0.13 ENST00000472441.1
TM4SF1
transmembrane 4 L six family member 1
chr15_+_49913201 0.13 ENST00000329873.5
ENST00000558653.1
ENST00000559164.1
ENST00000560632.1
ENST00000559405.1
ENST00000251250.6
DTWD1
DTW domain containing 1
chr3_-_143567262 0.13 ENST00000474151.1
ENST00000316549.6
SLC9A9
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr11_+_6411670 0.13 ENST00000530395.1
ENST00000527275.1
SMPD1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr5_-_81046904 0.13 ENST00000515395.1
SSBP2
single-stranded DNA binding protein 2
chr9_+_123884038 0.13 ENST00000373847.1
CNTRL
centriolin
chr4_+_8183793 0.13 ENST00000509119.1
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr2_+_233925064 0.13 ENST00000359570.5
ENST00000538935.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr6_+_41021027 0.13 ENST00000244669.2
APOBEC2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr15_+_49913175 0.12 ENST00000403028.3
DTWD1
DTW domain containing 1
chr12_+_62654155 0.12 ENST00000312635.6
ENST00000393654.3
ENST00000549237.1
USP15
ubiquitin specific peptidase 15
chr15_-_31283798 0.12 ENST00000435680.1
ENST00000425768.1
MTMR10
myotubularin related protein 10
chr12_+_34175398 0.12 ENST00000538927.1
ALG10
ALG10, alpha-1,2-glucosyltransferase
chr8_-_8318847 0.12 ENST00000521218.1
CTA-398F10.2
CTA-398F10.2
chr19_-_11849697 0.12 ENST00000586121.1
ENST00000431998.1
ENST00000341191.6
ENST00000545749.1
ENST00000440527.1
ZNF823
zinc finger protein 823
chr5_-_81046841 0.12 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
SSBP2
single-stranded DNA binding protein 2
chr6_-_119031228 0.12 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L
centrosomal protein 85kDa-like
chr9_-_123639600 0.11 ENST00000373896.3
PHF19
PHD finger protein 19
chrX_-_101397433 0.11 ENST00000372774.3
TCEAL6
transcription elongation factor A (SII)-like 6
chr4_-_114682224 0.11 ENST00000342666.5
ENST00000515496.1
ENST00000514328.1
ENST00000508738.1
ENST00000379773.2
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr13_+_73302047 0.11 ENST00000377814.2
ENST00000377815.3
ENST00000390667.5
BORA
bora, aurora kinase A activator
chr11_+_64052294 0.11 ENST00000536667.1
GPR137
G protein-coupled receptor 137
chr16_+_2588012 0.11 ENST00000354836.5
ENST00000389224.3
PDPK1
3-phosphoinositide dependent protein kinase-1
chr12_+_97306295 0.11 ENST00000457368.2
NEDD1
neural precursor cell expressed, developmentally down-regulated 1
chr7_-_156685841 0.11 ENST00000354505.4
ENST00000540390.1
LMBR1
limb development membrane protein 1
chr17_+_13972807 0.11 ENST00000429152.2
ENST00000261643.3
ENST00000536205.1
ENST00000537334.1
COX10
cytochrome c oxidase assembly homolog 10 (yeast)
chr3_-_142166846 0.11 ENST00000463916.1
ENST00000544157.1
XRN1
5'-3' exoribonuclease 1
chr14_-_92198403 0.11 ENST00000553329.1
ENST00000256343.3
CATSPERB
catsper channel auxiliary subunit beta
chr9_-_86432547 0.11 ENST00000376365.3
ENST00000376371.2
GKAP1
G kinase anchoring protein 1
chr3_+_111260980 0.11 ENST00000438817.2
CD96
CD96 molecule
chr22_-_50219548 0.11 ENST00000404034.1
BRD1
bromodomain containing 1
chr15_+_59908633 0.10 ENST00000559626.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr19_+_36393422 0.10 ENST00000437550.2
HCST
hematopoietic cell signal transducer
chr11_+_27062502 0.10 ENST00000263182.3
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr21_+_38792602 0.10 ENST00000398960.2
ENST00000398956.2
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr11_-_67415048 0.10 ENST00000529256.1
ACY3
aspartoacylase (aminocyclase) 3
chr15_-_37391614 0.10 ENST00000219869.9
MEIS2
Meis homeobox 2
chr22_-_37172111 0.10 ENST00000417951.2
ENST00000430701.1
ENST00000433985.2
IFT27
intraflagellar transport 27 homolog (Chlamydomonas)
chr6_-_4347271 0.10 ENST00000437430.2
RP3-527G5.1
RP3-527G5.1
chr4_-_114682364 0.10 ENST00000511664.1
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr7_+_99971129 0.10 ENST00000394000.2
ENST00000350573.2
PILRA
paired immunoglobin-like type 2 receptor alpha
chr19_-_12551849 0.10 ENST00000595562.1
ENST00000301547.5
CTD-3105H18.16
ZNF443
Uncharacterized protein
zinc finger protein 443
chr19_+_52800410 0.10 ENST00000595962.1
ENST00000598016.1
ENST00000334564.7
ENST00000490272.1
ZNF480
zinc finger protein 480
chr21_-_34144157 0.10 ENST00000331923.4
PAXBP1
PAX3 and PAX7 binding protein 1
chr7_+_70229899 0.09 ENST00000443672.1
AUTS2
autism susceptibility candidate 2
chr1_+_77333117 0.09 ENST00000477717.1
ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr4_+_159593418 0.09 ENST00000507475.1
ENST00000307738.5
ETFDH
electron-transferring-flavoprotein dehydrogenase
chr12_+_11081828 0.09 ENST00000381847.3
ENST00000396400.3
PRH2
proline-rich protein HaeIII subfamily 2
chr2_+_62900986 0.09 ENST00000405015.3
ENST00000413434.1
ENST00000426940.1
ENST00000449820.1
EHBP1
EH domain binding protein 1
chr11_-_71810258 0.09 ENST00000544594.1
LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr16_-_20817753 0.09 ENST00000389345.5
ENST00000300005.3
ENST00000357967.4
ENST00000569729.1
ERI2
ERI1 exoribonuclease family member 2
chr5_-_81046922 0.09 ENST00000514493.1
ENST00000320672.4
SSBP2
single-stranded DNA binding protein 2
chr2_+_113321939 0.08 ENST00000458012.2
POLR1B
polymerase (RNA) I polypeptide B, 128kDa
chr10_-_73848764 0.08 ENST00000317376.4
ENST00000412663.1
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr12_+_57522692 0.08 ENST00000554174.1
LRP1
low density lipoprotein receptor-related protein 1
chr19_+_9296279 0.08 ENST00000344248.2
OR7D2
olfactory receptor, family 7, subfamily D, member 2
chr15_-_77197620 0.08 ENST00000565970.1
ENST00000563290.1
ENST00000565372.1
ENST00000564177.1
ENST00000568382.1
ENST00000563919.1
SCAPER
S-phase cyclin A-associated protein in the ER
chr17_-_71223839 0.08 ENST00000579872.1
ENST00000580032.1
FAM104A
family with sequence similarity 104, member A
chr10_+_28822636 0.08 ENST00000442148.1
ENST00000448193.1
WAC
WW domain containing adaptor with coiled-coil
chr12_-_11036844 0.08 ENST00000428168.2
PRH1
proline-rich protein HaeIII subfamily 1
chr7_-_148580563 0.08 ENST00000476773.1
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr5_-_55008101 0.08 ENST00000506624.1
ENST00000513275.1
ENST00000513993.1
SLC38A9
solute carrier family 38, member 9
chr1_+_186649754 0.08 ENST00000608917.1
RP5-973M2.2
RP5-973M2.2
chr13_+_33160553 0.08 ENST00000315596.10
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr3_+_183899770 0.08 ENST00000442686.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr12_+_69186125 0.08 ENST00000399333.3
AC124890.1
HCG1774533, isoform CRA_a; PRO2268; Uncharacterized protein
chr10_+_94608218 0.08 ENST00000371543.1
EXOC6
exocyst complex component 6
chr15_+_36871983 0.08 ENST00000437989.2
ENST00000569302.1
C15orf41
chromosome 15 open reading frame 41
chr12_-_75784669 0.08 ENST00000552497.1
ENST00000551829.1
ENST00000436898.1
ENST00000442339.2
CAPS2
calcyphosine 2
chr1_+_222886694 0.08 ENST00000426638.1
ENST00000537020.1
ENST00000539697.1
BROX
BRO1 domain and CAAX motif containing
chr8_+_38244638 0.08 ENST00000526356.1
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr2_-_183903133 0.08 ENST00000361354.4
NCKAP1
NCK-associated protein 1
chr21_-_34143971 0.08 ENST00000290178.4
PAXBP1
PAX3 and PAX7 binding protein 1
chr17_+_7621045 0.07 ENST00000570791.1
DNAH2
dynein, axonemal, heavy chain 2
chr16_+_16484691 0.07 ENST00000344087.4
NPIPA7
nuclear pore complex interacting protein family, member A7
chr6_+_42123141 0.07 ENST00000418175.1
ENST00000541991.1
ENST00000053469.4
ENST00000394237.1
ENST00000372963.1
GUCA1A
RP1-139D8.6
guanylate cyclase activator 1A (retina)
RP1-139D8.6
chr16_+_2587965 0.07 ENST00000342085.4
ENST00000566659.1
PDPK1
3-phosphoinositide dependent protein kinase-1
chr4_+_88928777 0.07 ENST00000237596.2
PKD2
polycystic kidney disease 2 (autosomal dominant)
chr2_+_175260451 0.07 ENST00000458563.1
ENST00000409673.3
ENST00000272732.6
ENST00000435964.1
SCRN3
secernin 3
chr3_-_33481835 0.07 ENST00000283629.3
UBP1
upstream binding protein 1 (LBP-1a)
chr9_+_34652164 0.07 ENST00000441545.2
ENST00000553620.1
IL11RA
interleukin 11 receptor, alpha
chr6_+_155334780 0.07 ENST00000538270.1
ENST00000535231.1
TIAM2
T-cell lymphoma invasion and metastasis 2
chr19_-_58951496 0.07 ENST00000254166.3
ZNF132
zinc finger protein 132
chr15_-_37392086 0.07 ENST00000561208.1
MEIS2
Meis homeobox 2
chr10_+_121485588 0.07 ENST00000361976.2
ENST00000369083.3
INPP5F
inositol polyphosphate-5-phosphatase F
chr10_+_114710516 0.07 ENST00000542695.1
ENST00000346198.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr12_+_57522439 0.07 ENST00000338962.4
LRP1
low density lipoprotein receptor-related protein 1
chr5_+_118407053 0.07 ENST00000311085.8
ENST00000539542.1
DMXL1
Dmx-like 1
chr2_-_37068530 0.07 ENST00000593798.1
AC007382.1
Uncharacterized protein
chr1_-_203151933 0.07 ENST00000404436.2
CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr7_+_99971068 0.06 ENST00000198536.2
ENST00000453419.1
PILRA
paired immunoglobin-like type 2 receptor alpha
chr6_-_28220002 0.06 ENST00000377294.2
ZKSCAN4
zinc finger with KRAB and SCAN domains 4
chr18_+_39535239 0.06 ENST00000585528.1
PIK3C3
phosphatidylinositol 3-kinase, catalytic subunit type 3
chr6_-_131949200 0.06 ENST00000539158.1
ENST00000368058.1
MED23
mediator complex subunit 23
chr10_-_124768300 0.06 ENST00000368886.5
IKZF5
IKAROS family zinc finger 5 (Pegasus)
chr13_+_24844857 0.06 ENST00000409126.1
ENST00000343003.6
SPATA13
spermatogenesis associated 13
chr7_+_94536514 0.06 ENST00000413325.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr16_+_29789561 0.06 ENST00000400752.4
ZG16
zymogen granule protein 16
chr10_-_99052382 0.06 ENST00000453547.2
ENST00000316676.8
ENST00000358308.3
ENST00000466484.1
ENST00000358531.4
ARHGAP19-SLIT1
ARHGAP19
ARHGAP19-SLIT1 readthrough (NMD candidate)
Rho GTPase activating protein 19
chr5_-_52405564 0.06 ENST00000510818.2
ENST00000396954.3
ENST00000508922.1
ENST00000361377.4
ENST00000582677.1
ENST00000584946.1
ENST00000450852.3
MOCS2
molybdenum cofactor synthesis 2
chr7_-_7575477 0.06 ENST00000399429.3
COL28A1
collagen, type XXVIII, alpha 1
chr16_+_57139933 0.06 ENST00000566259.1
CPNE2
copine II
chr1_-_247335269 0.06 ENST00000543802.2
ENST00000491356.1
ENST00000472531.1
ENST00000340684.6
ZNF124
zinc finger protein 124
chr1_+_210406121 0.06 ENST00000367012.3
SERTAD4
SERTA domain containing 4
chr16_+_618837 0.06 ENST00000409439.2
PIGQ
phosphatidylinositol glycan anchor biosynthesis, class Q
chr10_-_118765081 0.06 ENST00000392903.2
ENST00000355371.4
KIAA1598
KIAA1598
chr5_-_94620239 0.06 ENST00000515393.1
MCTP1
multiple C2 domains, transmembrane 1
chr22_+_20905286 0.06 ENST00000428629.1
MED15
mediator complex subunit 15
chr18_+_48918368 0.05 ENST00000583982.1
ENST00000578152.1
ENST00000583609.1
ENST00000435144.1
ENST00000580841.1
RP11-267C16.1
RP11-267C16.1
chr5_-_55008136 0.05 ENST00000503891.1
ENST00000507109.1
SLC38A9
solute carrier family 38, member 9
chr12_+_85430110 0.05 ENST00000393212.3
ENST00000393217.2
LRRIQ1
leucine-rich repeats and IQ motif containing 1
chr7_-_91772263 0.05 ENST00000435873.1
CYP51A1
cytochrome P450, family 51, subfamily A, polypeptide 1
chr22_+_50946645 0.05 ENST00000420993.2
ENST00000395698.3
ENST00000395701.3
ENST00000523045.1
ENST00000299821.11
NCAPH2
non-SMC condensin II complex, subunit H2
chr18_-_46987000 0.05 ENST00000442713.2
ENST00000269445.6
DYM
dymeclin
chr4_+_146539415 0.05 ENST00000281317.5
MMAA
methylmalonic aciduria (cobalamin deficiency) cblA type
chr8_-_18541603 0.05 ENST00000428502.2
PSD3
pleckstrin and Sec7 domain containing 3

Network of associatons between targets according to the STRING database.

First level regulatory network of PKNOX1_TGIF2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 0.5 GO:0070295 renal water absorption(GO:0070295)
0.1 0.4 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 0.2 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.1 0.5 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.1 0.2 GO:0030070 insulin processing(GO:0030070)
0.1 0.2 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.2 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535) regulation of positive thymic T cell selection(GO:1902232)
0.1 0.2 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 0.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.2 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0 0.1 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.1 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.0 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.3 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.1 GO:0097359 UDP-glucosylation(GO:0097359)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.1 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.0 0.4 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.1 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.1 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0033488 cholesterol biosynthetic process via 24,25-dihydrolanosterol(GO:0033488)
0.0 0.2 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.0 GO:2000742 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.2 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.6 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.4 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.0 GO:0061110 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.3 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.3 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0006449 regulation of translational termination(GO:0006449)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.4 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.3 1.0 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 0.5 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.2 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.2 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.1 0.2 GO:0019808 polyamine binding(GO:0019808)
0.1 0.2 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.2 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.8 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.2 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 0.4 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.2 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.0 0.4 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.3 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.1 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.5 GO:0008430 selenium binding(GO:0008430)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.1 GO:0048763 HLH domain binding(GO:0043398) calcium-induced calcium release activity(GO:0048763)
0.0 0.1 GO:0008398 sterol 14-demethylase activity(GO:0008398)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.0 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.0 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.0 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 PID S1P S1P4 PATHWAY S1P4 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.6 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.4 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition