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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PGR

Z-value: 0.49

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Transcription factors associated with PGR

Gene Symbol Gene ID Gene Info
PGR
ENSG00000082175.10 progesterone receptor

Activity profile of PGR motif

Sorted Z-values of PGR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_22766766 0.55 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr3_+_52454971 0.39 ENST00000465863.1
PHF7
PHD finger protein 7
chr7_-_75241096 0.27 ENST00000420909.1
HIP1
huntingtin interacting protein 1
chr17_+_67590125 0.24 ENST00000591334.1
AC003051.1
AC003051.1
chr5_+_148443049 0.22 ENST00000515304.1
ENST00000507318.1
CTC-529P8.1
CTC-529P8.1
chr17_+_46970134 0.22 ENST00000503641.1
ENST00000514808.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr15_+_31658349 0.21 ENST00000558844.1
KLF13
Kruppel-like factor 13
chr6_+_30951487 0.21 ENST00000486149.2
ENST00000376296.3
MUC21
mucin 21, cell surface associated
chr17_-_7760457 0.18 ENST00000576384.1
LSMD1
LSM domain containing 1
chr16_+_58497274 0.18 ENST00000564207.1
NDRG4
NDRG family member 4
chr12_-_53575120 0.17 ENST00000542115.1
CSAD
cysteine sulfinic acid decarboxylase
chr17_+_67759813 0.17 ENST00000587241.1
AC003051.1
AC003051.1
chr19_-_41903161 0.17 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
EXOSC5
exosome component 5
chr17_+_46970127 0.16 ENST00000355938.5
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr5_-_95018660 0.16 ENST00000395899.3
ENST00000274432.8
SPATA9
spermatogenesis associated 9
chr3_-_139195350 0.15 ENST00000232217.2
RBP2
retinol binding protein 2, cellular
chr16_-_28506840 0.15 ENST00000569430.1
CLN3
ceroid-lipofuscinosis, neuronal 3
chr17_+_25958174 0.15 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
LGALS9
lectin, galactoside-binding, soluble, 9
chr9_-_34665983 0.15 ENST00000416454.1
ENST00000544078.2
ENST00000421828.2
ENST00000423809.1
RP11-195F19.5
HCG2040265, isoform CRA_a; Uncharacterized protein; cDNA FLJ50015
chr7_-_127671674 0.15 ENST00000478726.1
LRRC4
leucine rich repeat containing 4
chr10_+_69865866 0.15 ENST00000354393.2
MYPN
myopalladin
chr8_+_40010989 0.13 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chrX_-_133792480 0.13 ENST00000359237.4
PLAC1
placenta-specific 1
chr6_+_27107053 0.13 ENST00000354348.2
HIST1H4I
histone cluster 1, H4i
chr17_-_15522826 0.13 ENST00000395906.3
CDRT1
CMT1A duplicated region transcript 1
chr4_+_79567314 0.13 ENST00000503539.1
ENST00000504675.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr11_-_615570 0.13 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chr3_-_114035026 0.13 ENST00000570269.1
RP11-553L6.5
RP11-553L6.5
chr15_+_67841330 0.13 ENST00000354498.5
MAP2K5
mitogen-activated protein kinase kinase 5
chrX_+_109602039 0.13 ENST00000520821.1
RGAG1
retrotransposon gag domain containing 1
chr17_-_27188984 0.13 ENST00000582320.2
MIR144
microRNA 451b
chr1_+_209859510 0.12 ENST00000367028.2
ENST00000261465.1
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr16_+_86600857 0.12 ENST00000320354.4
FOXC2
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr12_-_122238464 0.12 ENST00000546227.1
RHOF
ras homolog family member F (in filopodia)
chr20_+_35090150 0.12 ENST00000340491.4
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr17_+_38119216 0.11 ENST00000301659.4
GSDMA
gasdermin A
chr17_-_15554940 0.11 ENST00000455584.2
RP11-385D13.1
Uncharacterized protein
chr15_-_74726283 0.11 ENST00000543145.2
SEMA7A
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr15_-_45406385 0.11 ENST00000389039.6
DUOX2
dual oxidase 2
chr12_-_7244469 0.11 ENST00000538050.1
ENST00000536053.2
C1R
complement component 1, r subcomponent
chr1_-_205290865 0.11 ENST00000367157.3
NUAK2
NUAK family, SNF1-like kinase, 2
chr6_-_75915757 0.11 ENST00000322507.8
COL12A1
collagen, type XII, alpha 1
chr2_-_216300784 0.11 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1
fibronectin 1
chr13_+_78315466 0.10 ENST00000314070.5
ENST00000462234.1
SLAIN1
SLAIN motif family, member 1
chr17_+_73997796 0.10 ENST00000586261.1
CDK3
cyclin-dependent kinase 3
chr4_+_117220016 0.10 ENST00000604093.1
MTRNR2L13
MT-RNR2-like 13 (pseudogene)
chr8_-_116681686 0.10 ENST00000519815.1
TRPS1
trichorhinophalangeal syndrome I
chr4_+_79567362 0.10 ENST00000512322.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr2_-_220034745 0.10 ENST00000455516.2
ENST00000396775.3
ENST00000295738.7
SLC23A3
solute carrier family 23, member 3
chr3_+_125985620 0.10 ENST00000511512.1
ENST00000512435.1
RP11-71E19.1
RP11-71E19.1
chr2_+_9778872 0.09 ENST00000478468.1
RP11-521D12.1
RP11-521D12.1
chr6_-_154831779 0.09 ENST00000607772.1
CNKSR3
CNKSR family member 3
chr14_+_24674926 0.09 ENST00000339917.5
ENST00000556621.1
ENST00000287913.6
ENST00000428351.2
ENST00000555092.1
TSSK4
testis-specific serine kinase 4
chr6_-_32908792 0.09 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr8_-_143851203 0.09 ENST00000521396.1
ENST00000317543.7
LYNX1
Ly6/neurotoxin 1
chr2_-_25451065 0.09 ENST00000606328.1
RP11-458N5.1
RP11-458N5.1
chr5_-_121413974 0.09 ENST00000231004.4
LOX
lysyl oxidase
chr7_-_14026063 0.08 ENST00000443608.1
ENST00000438956.1
ETV1
ets variant 1
chr1_+_41174988 0.08 ENST00000372652.1
NFYC
nuclear transcription factor Y, gamma
chr17_+_61086917 0.08 ENST00000424789.2
ENST00000389520.4
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr17_+_46970178 0.08 ENST00000393366.2
ENST00000506855.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr15_+_54305101 0.08 ENST00000260323.11
ENST00000545554.1
ENST00000537900.1
UNC13C
unc-13 homolog C (C. elegans)
chr2_+_64681103 0.08 ENST00000464281.1
LGALSL
lectin, galactoside-binding-like
chr11_+_123396528 0.08 ENST00000322282.7
ENST00000529750.1
GRAMD1B
GRAM domain containing 1B
chr6_-_32908765 0.08 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr13_+_78315528 0.08 ENST00000496045.1
SLAIN1
SLAIN motif family, member 1
chr20_+_25388293 0.08 ENST00000262460.4
ENST00000429262.2
GINS1
GINS complex subunit 1 (Psf1 homolog)
chr11_-_10920838 0.08 ENST00000503469.2
CTD-2003C8.2
CTD-2003C8.2
chr6_-_24489842 0.08 ENST00000230036.1
GPLD1
glycosylphosphatidylinositol specific phospholipase D1
chr5_-_115872142 0.08 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr2_+_96991935 0.08 ENST00000361124.4
ENST00000420728.1
ENST00000542887.1
ITPRIPL1
inositol 1,4,5-trisphosphate receptor interacting protein-like 1
chr12_-_91505608 0.08 ENST00000266718.4
LUM
lumican
chr2_-_175711924 0.08 ENST00000444573.1
CHN1
chimerin 1
chr2_+_64681219 0.08 ENST00000238875.5
LGALSL
lectin, galactoside-binding-like
chr9_-_37034028 0.08 ENST00000520281.1
ENST00000446742.1
ENST00000522003.1
ENST00000523145.1
ENST00000414447.1
ENST00000377847.2
ENST00000377853.2
ENST00000377852.2
ENST00000523241.1
ENST00000520154.1
ENST00000358127.4
PAX5
paired box 5
chr5_-_180242576 0.08 ENST00000514438.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr3_+_187871060 0.07 ENST00000448637.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr8_+_22844913 0.07 ENST00000519685.1
RHOBTB2
Rho-related BTB domain containing 2
chr20_-_25320367 0.07 ENST00000450393.1
ENST00000491682.1
ABHD12
abhydrolase domain containing 12
chr11_-_65625014 0.07 ENST00000534784.1
CFL1
cofilin 1 (non-muscle)
chr6_+_30853002 0.07 ENST00000421124.2
ENST00000512725.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr2_+_232135245 0.07 ENST00000446447.1
ARMC9
armadillo repeat containing 9
chr17_-_46608272 0.07 ENST00000577092.1
ENST00000239174.6
HOXB1
homeobox B1
chr4_-_40516560 0.07 ENST00000513473.1
RBM47
RNA binding motif protein 47
chrX_-_130037198 0.07 ENST00000370935.1
ENST00000338144.3
ENST00000394363.1
ENOX2
ecto-NOX disulfide-thiol exchanger 2
chr11_-_75379479 0.07 ENST00000434603.2
MAP6
microtubule-associated protein 6
chr21_-_28215332 0.07 ENST00000517777.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr11_+_123396307 0.07 ENST00000456860.2
GRAMD1B
GRAM domain containing 1B
chr21_+_39668831 0.07 ENST00000419868.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr15_+_31619013 0.07 ENST00000307145.3
KLF13
Kruppel-like factor 13
chr7_-_5821314 0.07 ENST00000425013.2
ENST00000389902.3
RNF216
ring finger protein 216
chr8_-_26371608 0.07 ENST00000522362.2
PNMA2
paraneoplastic Ma antigen 2
chr17_+_41150793 0.07 ENST00000586277.1
RPL27
ribosomal protein L27
chr17_+_72667239 0.07 ENST00000402449.4
RAB37
RAB37, member RAS oncogene family
chr22_+_30279144 0.07 ENST00000401950.2
ENST00000333027.3
ENST00000445401.1
ENST00000323630.5
ENST00000351488.3
MTMR3
myotubularin related protein 3
chr5_+_66124590 0.07 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr2_+_113885138 0.07 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr19_-_51529849 0.07 ENST00000600362.1
ENST00000453757.3
ENST00000601671.1
KLK11
kallikrein-related peptidase 11
chr11_+_64851666 0.07 ENST00000525509.1
ENST00000294258.3
ENST00000526334.1
ZFPL1
zinc finger protein-like 1
chr15_+_94899183 0.06 ENST00000557742.1
MCTP2
multiple C2 domains, transmembrane 2
chr1_+_95975672 0.06 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1
RP11-286B14.1
chr7_-_92855762 0.06 ENST00000453812.2
ENST00000394468.2
HEPACAM2
HEPACAM family member 2
chr3_+_185046676 0.06 ENST00000428617.1
ENST00000443863.1
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr5_-_138718973 0.06 ENST00000353963.3
ENST00000348729.3
SLC23A1
solute carrier family 23 (ascorbic acid transporter), member 1
chr10_+_95372289 0.06 ENST00000371447.3
PDE6C
phosphodiesterase 6C, cGMP-specific, cone, alpha prime
chr3_-_128294929 0.06 ENST00000356020.2
C3orf27
chromosome 3 open reading frame 27
chr6_-_132834184 0.06 ENST00000367941.2
ENST00000367937.4
STX7
syntaxin 7
chr13_+_78315348 0.06 ENST00000441784.1
SLAIN1
SLAIN motif family, member 1
chr20_-_60573188 0.06 ENST00000474089.1
TAF4
TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
chrX_-_130037162 0.06 ENST00000432489.1
ENOX2
ecto-NOX disulfide-thiol exchanger 2
chr2_+_27440229 0.06 ENST00000264705.4
ENST00000403525.1
CAD
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr2_-_85641162 0.06 ENST00000447219.2
ENST00000409670.1
ENST00000409724.1
CAPG
capping protein (actin filament), gelsolin-like
chr11_+_64851729 0.06 ENST00000526791.1
ENST00000526945.1
ZFPL1
zinc finger protein-like 1
chr16_-_3306587 0.06 ENST00000541159.1
ENST00000536379.1
ENST00000219596.1
ENST00000339854.4
MEFV
Mediterranean fever
chr2_-_219537134 0.06 ENST00000295704.2
RNF25
ring finger protein 25
chr18_+_21529811 0.06 ENST00000588004.1
LAMA3
laminin, alpha 3
chr6_+_143447322 0.06 ENST00000458219.1
AIG1
androgen-induced 1
chr19_+_49377575 0.06 ENST00000600406.1
PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr5_-_179107975 0.06 ENST00000376974.4
CBY3
chibby homolog 3 (Drosophila)
chr4_-_7069760 0.06 ENST00000264954.4
GRPEL1
GrpE-like 1, mitochondrial (E. coli)
chr19_-_6333614 0.06 ENST00000301452.4
ACER1
alkaline ceramidase 1
chr5_+_139505520 0.06 ENST00000333305.3
IGIP
IgA-inducing protein
chr8_+_118532937 0.06 ENST00000297347.3
MED30
mediator complex subunit 30
chr8_+_70476088 0.06 ENST00000525999.1
SULF1
sulfatase 1
chr2_-_163695128 0.06 ENST00000332142.5
KCNH7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chrX_+_54834004 0.06 ENST00000375068.1
MAGED2
melanoma antigen family D, 2
chr6_-_43276535 0.05 ENST00000372569.3
ENST00000274990.4
CRIP3
cysteine-rich protein 3
chr4_-_23735183 0.05 ENST00000507666.1
RP11-380P13.2
RP11-380P13.2
chr6_+_30852738 0.05 ENST00000508312.1
ENST00000512336.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr12_+_56473628 0.05 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr9_+_82188077 0.05 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr1_-_154943212 0.05 ENST00000368445.5
ENST00000448116.2
ENST00000368449.4
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr6_+_112375462 0.05 ENST00000361714.1
WISP3
WNT1 inducible signaling pathway protein 3
chr17_+_22022437 0.05 ENST00000540040.1
MTRNR2L1
MT-RNR2-like 1
chr11_-_65625330 0.05 ENST00000531407.1
CFL1
cofilin 1 (non-muscle)
chr4_-_105416039 0.05 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr11_-_6502580 0.05 ENST00000423813.2
ENST00000396777.3
ARFIP2
ADP-ribosylation factor interacting protein 2
chr1_+_152691998 0.05 ENST00000368775.2
C1orf68
chromosome 1 open reading frame 68
chr4_-_87770416 0.05 ENST00000273905.6
SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter), member 6
chr7_-_27213893 0.05 ENST00000283921.4
HOXA10
homeobox A10
chr11_-_6502534 0.05 ENST00000254584.2
ENST00000525235.1
ENST00000445086.2
ARFIP2
ADP-ribosylation factor interacting protein 2
chr11_-_62358972 0.05 ENST00000278279.3
TUT1
terminal uridylyl transferase 1, U6 snRNA-specific
chrX_+_46940254 0.05 ENST00000336169.3
RGN
regucalcin
chr10_+_97709725 0.05 ENST00000472454.2
RP11-248J23.6
Protein LOC100652732
chrX_-_100641155 0.05 ENST00000372880.1
ENST00000308731.7
BTK
Bruton agammaglobulinemia tyrosine kinase
chr5_+_138629628 0.05 ENST00000508689.1
ENST00000514528.1
MATR3
matrin 3
chr12_+_27398584 0.05 ENST00000543246.1
STK38L
serine/threonine kinase 38 like
chr14_-_75330537 0.05 ENST00000556084.2
ENST00000556489.2
ENST00000445876.1
PROX2
prospero homeobox 2
chr4_-_88450612 0.05 ENST00000418378.1
ENST00000282470.6
SPARCL1
SPARC-like 1 (hevin)
chr2_+_105050794 0.05 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chr5_-_137374288 0.05 ENST00000514310.1
FAM13B
family with sequence similarity 13, member B
chr12_-_71551652 0.05 ENST00000546561.1
TSPAN8
tetraspanin 8
chr11_+_65627974 0.05 ENST00000525768.1
MUS81
MUS81 structure-specific endonuclease subunit
chr2_-_175711978 0.05 ENST00000409089.2
CHN1
chimerin 1
chrX_+_69672136 0.05 ENST00000374355.3
DLG3
discs, large homolog 3 (Drosophila)
chr3_-_114343039 0.05 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chrX_+_23352133 0.05 ENST00000379361.4
PTCHD1
patched domain containing 1
chrX_+_47093171 0.05 ENST00000377078.2
USP11
ubiquitin specific peptidase 11
chr11_-_26744908 0.05 ENST00000533617.1
SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr20_+_23420885 0.05 ENST00000246020.2
CSTL1
cystatin-like 1
chr11_-_88796803 0.05 ENST00000418177.2
ENST00000455756.2
GRM5
glutamate receptor, metabotropic 5
chr6_-_159466136 0.05 ENST00000367066.3
ENST00000326965.6
TAGAP
T-cell activation RhoGTPase activating protein
chr20_-_52612468 0.05 ENST00000422805.1
BCAS1
breast carcinoma amplified sequence 1
chr7_-_129845313 0.05 ENST00000397622.2
TMEM209
transmembrane protein 209
chr6_-_128222103 0.04 ENST00000434358.1
ENST00000543064.1
ENST00000368248.2
THEMIS
thymocyte selection associated
chr8_+_124968225 0.04 ENST00000399018.1
FER1L6
fer-1-like 6 (C. elegans)
chr1_+_41447609 0.04 ENST00000543104.1
CTPS1
CTP synthase 1
chr9_-_34729457 0.04 ENST00000378788.3
FAM205A
family with sequence similarity 205, member A
chr10_-_104178857 0.04 ENST00000020673.5
PSD
pleckstrin and Sec7 domain containing
chr14_+_23709555 0.04 ENST00000430154.2
C14orf164
chromosome 14 open reading frame 164
chr20_+_31446729 0.04 ENST00000400522.4
EFCAB8
EF-hand calcium binding domain 8
chr3_-_114343768 0.04 ENST00000393785.2
ZBTB20
zinc finger and BTB domain containing 20
chr6_+_167412835 0.04 ENST00000349556.4
FGFR1OP
FGFR1 oncogene partner
chr10_+_90562705 0.04 ENST00000539337.1
LIPM
lipase, family member M
chr1_-_154943002 0.04 ENST00000606391.1
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr11_-_115127611 0.04 ENST00000545094.1
CADM1
cell adhesion molecule 1
chr19_+_19431490 0.04 ENST00000392313.6
ENST00000262815.8
ENST00000609122.1
MAU2
MAU2 sister chromatid cohesion factor
chr5_+_138629337 0.04 ENST00000394805.3
ENST00000512876.1
ENST00000513678.1
MATR3
matrin 3
chr17_-_7760779 0.04 ENST00000335155.5
ENST00000575071.1
LSMD1
LSM domain containing 1
chr19_-_48059113 0.04 ENST00000391901.3
ENST00000314121.4
ENST00000448976.1
ZNF541
zinc finger protein 541
chr7_-_37026108 0.04 ENST00000396045.3
ELMO1
engulfment and cell motility 1
chr19_-_19144243 0.04 ENST00000594445.1
ENST00000452918.2
ENST00000600377.1
ENST00000337018.6
SUGP2
SURP and G patch domain containing 2
chr8_-_67974552 0.04 ENST00000357849.4
COPS5
COP9 signalosome subunit 5
chr6_+_108487245 0.04 ENST00000368986.4
NR2E1
nuclear receptor subfamily 2, group E, member 1
chrX_-_78622805 0.04 ENST00000373298.2
ITM2A
integral membrane protein 2A
chr16_+_50582222 0.04 ENST00000268459.3
NKD1
naked cuticle homolog 1 (Drosophila)
chr12_+_53848505 0.04 ENST00000552819.1
ENST00000455667.3
PCBP2
poly(rC) binding protein 2
chr2_-_158182410 0.04 ENST00000419116.2
ENST00000410096.1
ERMN
ermin, ERM-like protein
chr10_+_90562487 0.04 ENST00000404743.4
LIPM
lipase, family member M
chr6_-_10413112 0.04 ENST00000465858.1
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr20_+_34129770 0.04 ENST00000348547.2
ENST00000357394.4
ENST00000447986.1
ENST00000279052.6
ENST00000416206.1
ENST00000411577.1
ENST00000413587.1
ERGIC3
ERGIC and golgi 3
chr17_+_7761013 0.04 ENST00000571846.1
CYB5D1
cytochrome b5 domain containing 1
chr5_-_156536126 0.04 ENST00000522593.1
HAVCR2
hepatitis A virus cellular receptor 2
chr3_+_169539710 0.04 ENST00000340806.6
LRRIQ4
leucine-rich repeats and IQ motif containing 4
chr4_+_79567057 0.04 ENST00000503259.1
ENST00000507802.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr3_+_137906109 0.04 ENST00000481646.1
ENST00000469044.1
ENST00000491704.1
ENST00000461600.1
ARMC8
armadillo repeat containing 8
chr6_-_53013620 0.04 ENST00000259803.7
GCM1
glial cells missing homolog 1 (Drosophila)
chr4_-_71532207 0.04 ENST00000543780.1
ENST00000391614.3
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr17_+_65027509 0.04 ENST00000375684.1
AC005544.1
Uncharacterized protein
chr7_+_73442457 0.04 ENST00000438880.1
ENST00000414324.1
ENST00000380562.4
ELN
elastin

Network of associatons between targets according to the STRING database.

First level regulatory network of PGR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637)
0.1 0.3 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 0.3 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.0 0.2 GO:0042412 taurine biosynthetic process(GO:0042412)
0.0 0.1 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) glomerular endothelium development(GO:0072011) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.0 0.2 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.1 GO:1904235 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.0 0.2 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.1 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.1 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.1 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.1 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0 0.1 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.3 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.0 GO:0002519 natural killer cell tolerance induction(GO:0002519)
0.0 0.1 GO:0010982 negative regulation of triglyceride catabolic process(GO:0010897) regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0 0.1 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.1 GO:0042335 cuticle development(GO:0042335) hypophysis morphogenesis(GO:0048850)
0.0 0.1 GO:0051510 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.1 GO:1903625 negative regulation of sperm motility(GO:1901318) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0 0.1 GO:0002368 B cell cytokine production(GO:0002368)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.0 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.0 GO:0048691 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.0 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.0 GO:0002118 aggressive behavior(GO:0002118)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.2 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 0.1 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.0 0.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.1 GO:0071633 dihydroceramidase activity(GO:0071633)
0.0 0.0 GO:0048257 3'-flap endonuclease activity(GO:0048257)
0.0 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 ST STAT3 PATHWAY STAT3 Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease