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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PDX1

Z-value: 0.64

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Transcription factors associated with PDX1

Gene Symbol Gene ID Gene Info
PDX1
ENSG00000139515.5 pancreatic and duodenal homeobox 1

Activity profile of PDX1 motif

Sorted Z-values of PDX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_37723336 0.62 ENST00000450180.1
GPR141
G protein-coupled receptor 141
chr12_-_86650077 0.62 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr5_+_66300464 0.41 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr6_+_43968306 0.40 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223
chromosome 6 open reading frame 223
chr5_-_56778635 0.35 ENST00000423391.1
ACTBL2
actin, beta-like 2
chr2_+_66918558 0.35 ENST00000435389.1
ENST00000428590.1
ENST00000412944.1
AC007392.3
AC007392.3
chr17_-_77924627 0.30 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
TBC1D16
TBC1 domain family, member 16
chr5_+_66300446 0.29 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr8_+_32579321 0.28 ENST00000522402.1
NRG1
neuregulin 1
chr9_-_5339873 0.27 ENST00000223862.1
ENST00000223858.4
RLN1
relaxin 1
chr1_-_152386732 0.26 ENST00000271835.3
CRNN
cornulin
chr15_+_63188009 0.25 ENST00000557900.1
RP11-1069G10.2
RP11-1069G10.2
chr8_+_32579341 0.25 ENST00000519240.1
ENST00000539990.1
NRG1
neuregulin 1
chr4_+_71384257 0.23 ENST00000339336.4
AMTN
amelotin
chr3_+_111718173 0.21 ENST00000494932.1
TAGLN3
transgelin 3
chr7_+_129015484 0.21 ENST00000490911.1
AHCYL2
adenosylhomocysteinase-like 2
chr12_-_52828147 0.21 ENST00000252245.5
KRT75
keratin 75
chr13_-_30683005 0.20 ENST00000413591.1
ENST00000432770.1
LINC00365
long intergenic non-protein coding RNA 365
chr2_+_45168875 0.20 ENST00000260653.3
SIX3
SIX homeobox 3
chr11_+_110001723 0.20 ENST00000528673.1
ZC3H12C
zinc finger CCCH-type containing 12C
chr2_+_138721850 0.20 ENST00000329366.4
ENST00000280097.3
HNMT
histamine N-methyltransferase
chr14_-_69261310 0.20 ENST00000336440.3
ZFP36L1
ZFP36 ring finger protein-like 1
chr13_+_78315466 0.19 ENST00000314070.5
ENST00000462234.1
SLAIN1
SLAIN motif family, member 1
chr4_+_71384300 0.18 ENST00000504451.1
AMTN
amelotin
chr5_+_172068232 0.18 ENST00000520919.1
ENST00000522853.1
ENST00000369800.5
NEURL1B
neuralized E3 ubiquitin protein ligase 1B
chr1_-_149859466 0.18 ENST00000331128.3
HIST2H2AB
histone cluster 2, H2ab
chr12_-_54813229 0.17 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr20_-_31124186 0.17 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr8_-_131399110 0.17 ENST00000521426.1
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr18_-_46784778 0.17 ENST00000582399.1
DYM
dymeclin
chr7_-_92777606 0.16 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr17_-_38928414 0.16 ENST00000335552.4
KRT26
keratin 26
chr8_+_32579271 0.16 ENST00000518084.1
NRG1
neuregulin 1
chr12_-_56321397 0.16 ENST00000557259.1
ENST00000549939.1
WIBG
within bgcn homolog (Drosophila)
chrX_+_10126488 0.15 ENST00000380829.1
ENST00000421085.2
ENST00000454850.1
CLCN4
chloride channel, voltage-sensitive 4
chr13_+_78315528 0.15 ENST00000496045.1
SLAIN1
SLAIN motif family, member 1
chr4_+_147145709 0.15 ENST00000504313.1
RP11-6L6.2
Uncharacterized protein
chr20_+_43990576 0.15 ENST00000372727.1
ENST00000414310.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr12_-_94673956 0.15 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr3_-_98235962 0.14 ENST00000513873.1
CLDND1
claudin domain containing 1
chr3_-_141747950 0.14 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr3_-_100565249 0.14 ENST00000495591.1
ENST00000383691.4
ENST00000466947.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr1_-_169396646 0.14 ENST00000367806.3
CCDC181
coiled-coil domain containing 181
chr14_+_59100774 0.14 ENST00000556859.1
ENST00000421793.1
DACT1
dishevelled-binding antagonist of beta-catenin 1
chr5_-_115890554 0.14 ENST00000509665.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr10_-_135379132 0.14 ENST00000343131.5
SYCE1
synaptonemal complex central element protein 1
chr15_+_67841330 0.13 ENST00000354498.5
MAP2K5
mitogen-activated protein kinase kinase 5
chr14_+_72052983 0.13 ENST00000358550.2
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr15_+_75080883 0.13 ENST00000567571.1
CSK
c-src tyrosine kinase
chr7_+_129015671 0.13 ENST00000466993.1
AHCYL2
adenosylhomocysteinase-like 2
chr12_+_49621658 0.13 ENST00000541364.1
TUBA1C
tubulin, alpha 1c
chr6_-_167040693 0.13 ENST00000366863.2
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr2_+_228736335 0.13 ENST00000440997.1
ENST00000545118.1
DAW1
dynein assembly factor with WDR repeat domains 1
chr9_-_5304432 0.13 ENST00000416837.1
ENST00000308420.3
RLN2
relaxin 2
chr4_-_109541539 0.13 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
RPL34-AS1
RPL34 antisense RNA 1 (head to head)
chr6_+_126221034 0.12 ENST00000433571.1
NCOA7
nuclear receptor coactivator 7
chr20_-_50419055 0.12 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr12_-_16761007 0.12 ENST00000354662.1
ENST00000441439.2
LMO3
LIM domain only 3 (rhombotin-like 2)
chr1_+_199996702 0.12 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr3_+_111717511 0.12 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr15_+_59279851 0.12 ENST00000348370.4
ENST00000434298.1
ENST00000559160.1
RNF111
ring finger protein 111
chr3_+_111718036 0.12 ENST00000455401.2
TAGLN3
transgelin 3
chr12_+_47610315 0.12 ENST00000548348.1
ENST00000549500.1
PCED1B
PC-esterase domain containing 1B
chr1_+_107683644 0.11 ENST00000370067.1
NTNG1
netrin G1
chr3_+_111717600 0.11 ENST00000273368.4
TAGLN3
transgelin 3
chr17_-_40337470 0.11 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr7_-_111424462 0.11 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr4_+_77356248 0.11 ENST00000296043.6
SHROOM3
shroom family member 3
chr6_+_13272904 0.11 ENST00000379335.3
ENST00000379329.1
PHACTR1
phosphatase and actin regulator 1
chr17_+_74846230 0.11 ENST00000592919.1
LINC00868
long intergenic non-protein coding RNA 868
chr4_+_53525573 0.11 ENST00000503051.1
USP46-AS1
USP46 antisense RNA 1
chr7_-_100860851 0.11 ENST00000223127.3
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr19_-_7698599 0.11 ENST00000311069.5
PCP2
Purkinje cell protein 2
chr2_-_166930131 0.11 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr3_+_108541545 0.10 ENST00000295756.6
TRAT1
T cell receptor associated transmembrane adaptor 1
chr4_-_103749179 0.10 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr15_-_100882191 0.10 ENST00000268070.4
ADAMTS17
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chrX_-_106146547 0.10 ENST00000276173.4
ENST00000411805.1
RIPPLY1
ripply transcriptional repressor 1
chr18_+_3447572 0.10 ENST00000548489.2
TGIF1
TGFB-induced factor homeobox 1
chrX_-_19817869 0.10 ENST00000379698.4
SH3KBP1
SH3-domain kinase binding protein 1
chr17_-_8301132 0.10 ENST00000399398.2
RNF222
ring finger protein 222
chr17_-_39165366 0.10 ENST00000391588.1
KRTAP3-1
keratin associated protein 3-1
chr11_+_65554493 0.10 ENST00000335987.3
OVOL1
ovo-like zinc finger 1
chr11_+_15136462 0.10 ENST00000379556.3
ENST00000424273.1
INSC
inscuteable homolog (Drosophila)
chr19_+_11071546 0.10 ENST00000358026.2
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr11_+_115498761 0.09 ENST00000424313.2
AP000997.1
AP000997.1
chr11_-_36619771 0.09 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
RAG2
recombination activating gene 2
chr12_-_51611477 0.09 ENST00000389243.4
POU6F1
POU class 6 homeobox 1
chr11_-_129062093 0.09 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr21_+_17442799 0.09 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
LINC00478
long intergenic non-protein coding RNA 478
chr1_+_28586006 0.09 ENST00000253063.3
SESN2
sestrin 2
chr21_+_17792672 0.09 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr7_-_99716940 0.09 ENST00000440225.1
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr11_-_115630900 0.09 ENST00000537070.1
ENST00000499809.1
ENST00000514294.2
ENST00000535683.1
LINC00900
long intergenic non-protein coding RNA 900
chr13_-_46626820 0.08 ENST00000428921.1
ZC3H13
zinc finger CCCH-type containing 13
chrX_-_110655306 0.08 ENST00000371993.2
DCX
doublecortin
chr1_+_28261533 0.08 ENST00000411604.1
ENST00000373888.4
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr17_+_72931876 0.08 ENST00000328801.4
OTOP3
otopetrin 3
chr4_+_22999152 0.08 ENST00000511453.1
RP11-412P11.1
RP11-412P11.1
chr1_-_221509638 0.08 ENST00000439004.1
RP11-421L10.1
RP11-421L10.1
chr2_+_48541776 0.08 ENST00000413569.1
ENST00000340553.3
FOXN2
forkhead box N2
chr9_+_131037623 0.08 ENST00000495313.1
ENST00000372898.2
SWI5
SWI5 recombination repair homolog (yeast)
chr6_-_100912785 0.08 ENST00000369208.3
SIM1
single-minded family bHLH transcription factor 1
chr11_+_125034586 0.08 ENST00000298282.9
PKNOX2
PBX/knotted 1 homeobox 2
chr8_-_42234745 0.08 ENST00000220812.2
DKK4
dickkopf WNT signaling pathway inhibitor 4
chr4_-_70518941 0.08 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1
UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr12_-_6233828 0.08 ENST00000572068.1
ENST00000261405.5
VWF
von Willebrand factor
chr12_-_16761117 0.08 ENST00000538051.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr8_+_22844913 0.08 ENST00000519685.1
RHOBTB2
Rho-related BTB domain containing 2
chr15_+_28624878 0.08 ENST00000450328.2
GOLGA8F
golgin A8 family, member F
chr4_-_138453606 0.07 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr9_-_28670283 0.07 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chr20_+_60174827 0.07 ENST00000543233.1
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr1_-_2458026 0.07 ENST00000435556.3
ENST00000378466.3
PANK4
pantothenate kinase 4
chr6_-_25042231 0.07 ENST00000510784.2
FAM65B
family with sequence similarity 65, member B
chr11_-_31531121 0.07 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr1_-_21625486 0.07 ENST00000481130.2
ECE1
endothelin converting enzyme 1
chrX_+_133930798 0.07 ENST00000414371.2
FAM122C
family with sequence similarity 122C
chr7_+_99717230 0.07 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chr18_+_55888767 0.07 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr1_+_36621174 0.07 ENST00000429533.2
MAP7D1
MAP7 domain containing 1
chr1_+_36621529 0.07 ENST00000316156.4
MAP7D1
MAP7 domain containing 1
chr8_+_77593448 0.07 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr20_-_50418947 0.07 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr3_-_131756559 0.06 ENST00000505957.1
CPNE4
copine IV
chr1_+_151735431 0.06 ENST00000321531.5
ENST00000315067.8
OAZ3
ornithine decarboxylase antizyme 3
chr20_+_62795827 0.06 ENST00000328439.1
ENST00000536311.1
MYT1
myelin transcription factor 1
chr19_-_7968427 0.06 ENST00000539278.1
AC010336.1
Uncharacterized protein
chr2_-_208031943 0.06 ENST00000421199.1
ENST00000457962.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr8_+_55528627 0.06 ENST00000220676.1
RP1
retinitis pigmentosa 1 (autosomal dominant)
chr4_-_119759795 0.06 ENST00000419654.2
SEC24D
SEC24 family member D
chr10_+_24497704 0.06 ENST00000376456.4
ENST00000458595.1
KIAA1217
KIAA1217
chr5_-_54988559 0.06 ENST00000502247.1
SLC38A9
solute carrier family 38, member 9
chr15_+_43886057 0.06 ENST00000441322.1
ENST00000413657.2
ENST00000453733.1
CKMT1B
creatine kinase, mitochondrial 1B
chr1_+_160160283 0.06 ENST00000368079.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr5_-_140998616 0.06 ENST00000389054.3
ENST00000398562.2
ENST00000389057.5
ENST00000398566.3
ENST00000398557.4
ENST00000253811.6
DIAPH1
diaphanous-related formin 1
chr14_+_100485712 0.06 ENST00000544450.2
EVL
Enah/Vasp-like
chr12_+_81101277 0.06 ENST00000228641.3
MYF6
myogenic factor 6 (herculin)
chrX_-_64196351 0.06 ENST00000374839.3
ZC4H2
zinc finger, C4H2 domain containing
chr15_+_43986069 0.06 ENST00000415044.1
CKMT1A
creatine kinase, mitochondrial 1A
chr18_+_59000815 0.06 ENST00000262717.4
CDH20
cadherin 20, type 2
chr3_+_69985792 0.06 ENST00000531774.1
MITF
microphthalmia-associated transcription factor
chr11_-_8285405 0.05 ENST00000335790.3
ENST00000534484.1
LMO1
LIM domain only 1 (rhombotin 1)
chr2_-_145277569 0.05 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chr1_+_1846519 0.05 ENST00000378604.3
CALML6
calmodulin-like 6
chr7_-_14028488 0.05 ENST00000405358.4
ETV1
ets variant 1
chr7_-_33102338 0.05 ENST00000610140.1
NT5C3A
5'-nucleotidase, cytosolic IIIA
chrX_-_100129128 0.05 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
NOX1
NADPH oxidase 1
chr1_-_94147385 0.05 ENST00000260502.6
BCAR3
breast cancer anti-estrogen resistance 3
chr12_+_72332618 0.05 ENST00000333850.3
TPH2
tryptophan hydroxylase 2
chr4_-_41884620 0.05 ENST00000504870.1
LINC00682
long intergenic non-protein coding RNA 682
chr7_-_33102399 0.05 ENST00000242210.7
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr3_-_112127981 0.05 ENST00000486726.2
RP11-231E6.1
RP11-231E6.1
chr7_+_114055052 0.05 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2
forkhead box P2
chr14_-_47351391 0.05 ENST00000399222.3
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr17_+_43238438 0.05 ENST00000593138.1
ENST00000586681.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr20_+_30697298 0.05 ENST00000398022.2
TM9SF4
transmembrane 9 superfamily protein member 4
chr15_-_55562582 0.05 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr11_-_8290263 0.05 ENST00000428101.2
LMO1
LIM domain only 1 (rhombotin 1)
chr1_-_1709845 0.05 ENST00000341426.5
ENST00000344463.4
NADK
NAD kinase
chr8_-_10512569 0.05 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr1_+_160160346 0.05 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr9_-_16728161 0.05 ENST00000603713.1
ENST00000603313.1
BNC2
basonuclin 2
chr12_-_91576429 0.05 ENST00000552145.1
ENST00000546745.1
DCN
decorin
chr20_-_50418972 0.05 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr13_-_67802549 0.05 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr17_-_27418537 0.04 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr12_-_21928515 0.04 ENST00000537950.1
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr5_+_98109322 0.04 ENST00000513185.1
RGMB
repulsive guidance molecule family member b
chr12_+_56325231 0.04 ENST00000549368.1
DGKA
diacylglycerol kinase, alpha 80kDa
chrM_+_9207 0.04 ENST00000362079.2
MT-CO3
mitochondrially encoded cytochrome c oxidase III
chr5_-_140998481 0.04 ENST00000518047.1
DIAPH1
diaphanous-related formin 1
chr14_+_74034310 0.04 ENST00000538782.1
ACOT2
acyl-CoA thioesterase 2
chr5_-_96478466 0.04 ENST00000274382.4
LIX1
Lix1 homolog (chicken)
chr1_-_151431674 0.04 ENST00000531094.1
POGZ
pogo transposable element with ZNF domain
chr7_+_90012986 0.04 ENST00000416322.1
CLDN12
claudin 12
chr2_-_227050079 0.04 ENST00000423838.1
AC068138.1
AC068138.1
chr4_-_103749205 0.04 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr10_+_119302508 0.04 ENST00000442245.4
EMX2
empty spiracles homeobox 2
chr15_+_43985725 0.04 ENST00000413453.2
CKMT1A
creatine kinase, mitochondrial 1A
chr5_+_60933634 0.04 ENST00000505642.1
C5orf64
chromosome 5 open reading frame 64
chr6_+_34204642 0.04 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr19_+_13049413 0.04 ENST00000316448.5
ENST00000588454.1
CALR
calreticulin
chr21_-_31538971 0.04 ENST00000286808.3
CLDN17
claudin 17
chr21_+_17443434 0.04 ENST00000400178.2
LINC00478
long intergenic non-protein coding RNA 478
chr1_-_201140673 0.04 ENST00000367333.2
TMEM9
transmembrane protein 9
chr14_+_61654271 0.04 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH
protein kinase C, eta
chr12_-_14849470 0.03 ENST00000261170.3
GUCY2C
guanylate cyclase 2C (heat stable enterotoxin receptor)
chrX_-_64196307 0.03 ENST00000545618.1
ZC4H2
zinc finger, C4H2 domain containing
chr12_+_15699286 0.03 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO
protein tyrosine phosphatase, receptor type, O
chr19_+_641178 0.03 ENST00000166133.3
FGF22
fibroblast growth factor 22
chr21_-_35899113 0.03 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1
regulator of calcineurin 1
chr4_-_66536057 0.03 ENST00000273854.3
EPHA5
EPH receptor A5
chr3_-_74570291 0.03 ENST00000263665.6
CNTN3
contactin 3 (plasmacytoma associated)
chr16_+_24621546 0.03 ENST00000566108.1
CTD-2540M10.1
CTD-2540M10.1
chr8_+_38831683 0.03 ENST00000302495.4
HTRA4
HtrA serine peptidase 4
chr15_-_31393910 0.03 ENST00000397795.2
ENST00000256552.6
ENST00000559179.1
TRPM1
transient receptor potential cation channel, subfamily M, member 1
chr15_-_65407524 0.03 ENST00000559089.1
UBAP1L
ubiquitin associated protein 1-like
chr10_-_27529486 0.03 ENST00000375888.1
ACBD5
acyl-CoA binding domain containing 5
chr20_+_43538692 0.03 ENST00000217074.4
ENST00000255136.3
PABPC1L
poly(A) binding protein, cytoplasmic 1-like

Network of associatons between targets according to the STRING database.

First level regulatory network of PDX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.4 GO:0042488 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) positive regulation of tooth mineralization(GO:0070172)
0.0 0.2 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.2 GO:1901545 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.2 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.2 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:1901994 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.1 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0061373 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0045726 regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.0 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.1 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.0 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.0 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.2 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.0 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling