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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PBX3

Z-value: 1.64

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Transcription factors associated with PBX3

Gene Symbol Gene ID Gene Info
PBX3
ENSG00000167081.12 PBX homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PBX3hg19_v2_chr9_+_128509624_1285096580.721.0e-01Click!

Activity profile of PBX3 motif

Sorted Z-values of PBX3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_26859300 1.24 ENST00000494628.2
STIM2
stromal interaction molecule 2
chr12_+_65996599 1.07 ENST00000539116.1
ENST00000541391.1
RP11-221N13.3
RP11-221N13.3
chr7_-_64023441 1.00 ENST00000309683.6
ZNF680
zinc finger protein 680
chr11_-_73720276 0.97 ENST00000348534.4
UCP3
uncoupling protein 3 (mitochondrial, proton carrier)
chr4_-_87515202 0.95 ENST00000502302.1
ENST00000513186.1
MAPK10
mitogen-activated protein kinase 10
chr2_-_61765315 0.95 ENST00000406957.1
ENST00000401558.2
XPO1
exportin 1 (CRM1 homolog, yeast)
chr6_+_63921351 0.92 ENST00000370659.1
FKBP1C
FK506 binding protein 1C
chr20_+_52824367 0.89 ENST00000371419.2
PFDN4
prefoldin subunit 4
chr19_+_21324827 0.85 ENST00000600692.1
ENST00000599296.1
ENST00000594425.1
ENST00000311048.7
ZNF431
zinc finger protein 431
chr19_+_21688366 0.82 ENST00000358491.4
ENST00000597078.1
ZNF429
zinc finger protein 429
chr5_+_150406527 0.82 ENST00000520059.1
GPX3
glutathione peroxidase 3 (plasma)
chr1_-_247171347 0.82 ENST00000339986.7
ENST00000487338.2
ZNF695
zinc finger protein 695
chr19_+_21324863 0.80 ENST00000598331.1
ZNF431
zinc finger protein 431
chr6_-_46138676 0.80 ENST00000371383.2
ENST00000230565.3
ENPP5
ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
chr2_-_61765732 0.75 ENST00000443240.1
ENST00000436018.1
XPO1
exportin 1 (CRM1 homolog, yeast)
chr19_-_20844343 0.75 ENST00000595405.1
ZNF626
zinc finger protein 626
chr16_-_79634595 0.75 ENST00000326043.4
ENST00000393350.1
MAF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr3_-_195163584 0.73 ENST00000439666.1
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr1_+_85527987 0.71 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WDR63
WD repeat domain 63
chr9_+_96928516 0.69 ENST00000602703.1
RP11-2B6.3
RP11-2B6.3
chr19_+_24097675 0.67 ENST00000525354.2
ENST00000334589.5
ENST00000531821.2
ENST00000594466.1
ZNF726
zinc finger protein 726
chr19_-_12476443 0.66 ENST00000242804.4
ENST00000438182.1
ZNF442
zinc finger protein 442
chr19_+_21264943 0.65 ENST00000597424.1
ZNF714
zinc finger protein 714
chr7_+_116502605 0.65 ENST00000458284.2
ENST00000490693.1
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr3_+_111393659 0.65 ENST00000477665.1
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr7_+_64363625 0.64 ENST00000476120.1
ENST00000319636.5
ENST00000545510.1
ZNF273
zinc finger protein 273
chr4_-_23891693 0.63 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr19_-_12163754 0.61 ENST00000547628.1
ZNF878
zinc finger protein 878
chr8_-_80680078 0.61 ENST00000337919.5
ENST00000354724.3
HEY1
hes-related family bHLH transcription factor with YRPW motif 1
chr19_-_19843900 0.61 ENST00000344099.3
ZNF14
zinc finger protein 14
chr14_+_74960423 0.61 ENST00000556816.1
ENST00000298818.8
ENST00000554924.1
ISCA2
iron-sulfur cluster assembly 2
chrX_-_134049233 0.60 ENST00000370779.4
MOSPD1
motile sperm domain containing 1
chr11_-_27494309 0.60 ENST00000389858.4
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr19_+_19976683 0.59 ENST00000592725.1
ZNF253
zinc finger protein 253
chr1_+_100111479 0.59 ENST00000263174.4
PALMD
palmdelphin
chr4_+_331619 0.58 ENST00000505939.1
ENST00000240499.7
ZNF141
zinc finger protein 141
chr12_+_28343353 0.58 ENST00000539107.1
CCDC91
coiled-coil domain containing 91
chr8_+_26240414 0.58 ENST00000380629.2
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr9_+_40028620 0.57 ENST00000426179.1
AL353791.1
AL353791.1
chr19_-_49140692 0.57 ENST00000222122.5
DBP
D site of albumin promoter (albumin D-box) binding protein
chr1_-_152061537 0.57 ENST00000368806.1
TCHHL1
trichohyalin-like 1
chr16_-_29479154 0.56 ENST00000549950.1
RP11-345J4.3
Uncharacterized protein
chr2_+_65663812 0.56 ENST00000606978.1
ENST00000377977.3
ENST00000536804.1
AC074391.1
AC074391.1
chr11_-_27494279 0.56 ENST00000379214.4
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr5_+_2752216 0.56 ENST00000457752.2
C5orf38
chromosome 5 open reading frame 38
chr19_+_22235279 0.55 ENST00000594363.1
ENST00000597927.1
ENST00000594947.1
ZNF257
zinc finger protein 257
chr4_+_331578 0.55 ENST00000512994.1
ZNF141
zinc finger protein 141
chr4_-_89205879 0.55 ENST00000608933.1
ENST00000315194.4
ENST00000514204.1
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr7_+_64838712 0.55 ENST00000328747.7
ENST00000431504.1
ENST00000357512.2
ZNF92
zinc finger protein 92
chr19_+_24097706 0.55 ENST00000322487.7
ENST00000575986.1
ZNF726
zinc finger protein 726
chr17_+_57233087 0.55 ENST00000578777.1
ENST00000577457.1
ENST00000582995.1
PRR11
proline rich 11
chr19_+_21579908 0.54 ENST00000596302.1
ENST00000392288.2
ENST00000594390.1
ENST00000355504.4
ZNF493
zinc finger protein 493
chr7_+_64126535 0.53 ENST00000344930.3
ZNF107
zinc finger protein 107
chr19_+_21264980 0.53 ENST00000596053.1
ENST00000597086.1
ENST00000596143.1
ENST00000596367.1
ENST00000601416.1
ZNF714
zinc finger protein 714
chr8_-_93978309 0.53 ENST00000517858.1
ENST00000378861.5
TRIQK
triple QxxK/R motif containing
chr4_+_175204818 0.52 ENST00000503780.1
CEP44
centrosomal protein 44kDa
chr1_+_60280458 0.52 ENST00000455990.1
ENST00000371208.3
HOOK1
hook microtubule-tethering protein 1
chr7_+_116502527 0.52 ENST00000361183.3
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr19_+_20188830 0.52 ENST00000418063.2
ZNF90
zinc finger protein 90
chr19_-_12662314 0.51 ENST00000339282.7
ENST00000596193.1
ZNF564
zinc finger protein 564
chr6_+_41021027 0.51 ENST00000244669.2
APOBEC2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr12_+_25205155 0.50 ENST00000550945.1
LRMP
lymphoid-restricted membrane protein
chr1_+_6845578 0.50 ENST00000467404.2
ENST00000439411.2
CAMTA1
calmodulin binding transcription activator 1
chr19_+_12075844 0.50 ENST00000592625.1
ENST00000586494.1
ENST00000343949.5
ENST00000545530.1
ENST00000358987.3
ZNF763
zinc finger protein 763
chr1_+_100111580 0.49 ENST00000605497.1
PALMD
palmdelphin
chr18_-_14132422 0.49 ENST00000589498.1
ENST00000590202.1
ZNF519
zinc finger protein 519
chr4_-_175443484 0.49 ENST00000514584.1
ENST00000542498.1
ENST00000296521.7
ENST00000422112.2
ENST00000504433.1
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr3_-_25706368 0.49 ENST00000424225.1
TOP2B
topoisomerase (DNA) II beta 180kDa
chr7_+_64254793 0.49 ENST00000494380.1
ENST00000440155.2
ENST00000440598.1
ENST00000437743.1
ZNF138
zinc finger protein 138
chr19_+_21106081 0.49 ENST00000300540.3
ENST00000595854.1
ENST00000601284.1
ENST00000328178.8
ENST00000599885.1
ENST00000596476.1
ENST00000345030.6
ZNF85
zinc finger protein 85
chr16_-_29275800 0.49 ENST00000567984.1
RP11-426C22.6
RP11-426C22.6
chr19_-_22605136 0.49 ENST00000357774.5
ENST00000601553.1
ENST00000593657.1
ZNF98
zinc finger protein 98
chr7_+_64838786 0.48 ENST00000450302.2
ZNF92
zinc finger protein 92
chr1_-_243417762 0.48 ENST00000522191.1
CEP170
centrosomal protein 170kDa
chr4_-_106817137 0.48 ENST00000510876.1
INTS12
integrator complex subunit 12
chr6_-_41673552 0.47 ENST00000419574.1
ENST00000445214.1
TFEB
transcription factor EB
chr19_-_23433144 0.47 ENST00000418100.1
ENST00000597537.1
ENST00000597037.1
ZNF724P
zinc finger protein 724, pseudogene
chr9_+_74526384 0.46 ENST00000334731.2
ENST00000377031.3
C9orf85
chromosome 9 open reading frame 85
chr10_+_76586348 0.46 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
KAT6B
K(lysine) acetyltransferase 6B
chr1_-_935519 0.46 ENST00000428771.2
HES4
hes family bHLH transcription factor 4
chr8_+_101349823 0.46 ENST00000519566.1
KB-1991G8.1
KB-1991G8.1
chr1_+_62901968 0.45 ENST00000452143.1
ENST00000442679.1
ENST00000371146.1
USP1
ubiquitin specific peptidase 1
chr11_-_59633951 0.45 ENST00000257264.3
TCN1
transcobalamin I (vitamin B12 binding protein, R binder family)
chr19_-_11849697 0.44 ENST00000586121.1
ENST00000431998.1
ENST00000341191.6
ENST00000545749.1
ENST00000440527.1
ZNF823
zinc finger protein 823
chr9_-_119449483 0.44 ENST00000288520.5
ENST00000358637.4
ENST00000341734.4
ASTN2
astrotactin 2
chr19_+_20011731 0.44 ENST00000591366.1
ZNF93
zinc finger protein 93
chrX_-_47930980 0.44 ENST00000442455.3
ENST00000428686.1
ENST00000276054.4
ZNF630
zinc finger protein 630
chr14_+_37131058 0.43 ENST00000361487.6
PAX9
paired box 9
chr1_+_227751231 0.43 ENST00000343776.5
ENST00000608949.1
ENST00000397097.3
ZNF678
zinc finger protein 678
chr4_+_83956312 0.43 ENST00000509317.1
ENST00000503682.1
ENST00000511653.1
COPS4
COP9 signalosome subunit 4
chr4_+_95174445 0.43 ENST00000509418.1
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr11_-_73720122 0.43 ENST00000426995.2
UCP3
uncoupling protein 3 (mitochondrial, proton carrier)
chr8_-_95449155 0.43 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr8_-_90996459 0.43 ENST00000517337.1
ENST00000409330.1
NBN
nibrin
chr9_+_74526532 0.43 ENST00000486911.2
C9orf85
chromosome 9 open reading frame 85
chr19_-_12551849 0.43 ENST00000595562.1
ENST00000301547.5
CTD-3105H18.16
ZNF443
Uncharacterized protein
zinc finger protein 443
chr2_-_45236540 0.42 ENST00000303077.6
SIX2
SIX homeobox 2
chr1_+_7844312 0.42 ENST00000377541.1
PER3
period circadian clock 3
chr7_-_75368248 0.42 ENST00000434438.2
ENST00000336926.6
HIP1
huntingtin interacting protein 1
chr18_-_74844713 0.42 ENST00000397860.3
MBP
myelin basic protein
chr8_-_101964738 0.41 ENST00000523938.1
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr3_+_129207033 0.41 ENST00000507221.1
IFT122
intraflagellar transport 122 homolog (Chlamydomonas)
chr19_-_21512202 0.41 ENST00000356929.3
ZNF708
zinc finger protein 708
chr9_-_134615326 0.41 ENST00000438647.1
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr19_+_2977444 0.40 ENST00000246112.4
ENST00000453329.1
ENST00000482627.1
ENST00000452088.1
TLE6
transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
chr4_-_175443943 0.40 ENST00000296522.6
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr22_-_24126145 0.40 ENST00000598975.1
AP000349.1
Uncharacterized protein
chr9_+_34652164 0.40 ENST00000441545.2
ENST00000553620.1
IL11RA
interleukin 11 receptor, alpha
chr8_-_77912431 0.40 ENST00000357039.4
ENST00000522527.1
PEX2
peroxisomal biogenesis factor 2
chr7_+_72742178 0.39 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FKBP6
FK506 binding protein 6, 36kDa
chrX_-_134049262 0.39 ENST00000370783.3
MOSPD1
motile sperm domain containing 1
chr9_-_3525968 0.39 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
RFX3
regulatory factor X, 3 (influences HLA class II expression)
chr15_+_36994210 0.39 ENST00000562489.1
C15orf41
chromosome 15 open reading frame 41
chr14_+_54976603 0.39 ENST00000557317.1
CGRRF1
cell growth regulator with ring finger domain 1
chr4_+_124374 0.38 ENST00000511079.1
ENST00000513304.1
ENST00000513889.1
ENST00000510175.1
ZNF718
zinc finger protein 718
chr16_+_70680439 0.38 ENST00000288098.2
IL34
interleukin 34
chr22_-_29138386 0.38 ENST00000544772.1
CHEK2
checkpoint kinase 2
chr19_-_23941639 0.38 ENST00000395385.3
ENST00000531570.1
ENST00000528059.1
ZNF681
zinc finger protein 681
chr5_-_81046904 0.37 ENST00000515395.1
SSBP2
single-stranded DNA binding protein 2
chr18_+_12991339 0.37 ENST00000589596.1
ENST00000506447.1
ENST00000325971.8
CEP192
centrosomal protein 192kDa
chr14_-_82000140 0.37 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
SEL1L
sel-1 suppressor of lin-12-like (C. elegans)
chr19_-_49140609 0.36 ENST00000601104.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr3_-_88108192 0.36 ENST00000309534.6
CGGBP1
CGG triplet repeat binding protein 1
chr17_-_27405875 0.36 ENST00000359450.6
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr11_-_3400442 0.36 ENST00000429541.2
ENST00000532539.1
ZNF195
zinc finger protein 195
chr11_+_117014983 0.36 ENST00000527958.1
ENST00000419197.2
ENST00000304808.6
ENST00000529887.2
PAFAH1B2
platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
chr5_-_81046841 0.36 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
SSBP2
single-stranded DNA binding protein 2
chr8_+_38243721 0.36 ENST00000527334.1
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr3_-_148804275 0.36 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
HLTF
helicase-like transcription factor
chr4_+_83956237 0.35 ENST00000264389.2
COPS4
COP9 signalosome subunit 4
chr6_-_119031228 0.35 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L
centrosomal protein 85kDa-like
chrX_+_95939638 0.34 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
DIAPH2
diaphanous-related formin 2
chr19_-_20748541 0.34 ENST00000427401.4
ENST00000594419.1
ZNF737
zinc finger protein 737
chr19_-_23869999 0.34 ENST00000601935.1
ENST00000359788.4
ENST00000600313.1
ENST00000596211.1
ENST00000599168.1
ZNF675
zinc finger protein 675
chrX_-_63425561 0.33 ENST00000374869.3
ENST00000330258.3
AMER1
APC membrane recruitment protein 1
chr13_+_20532900 0.33 ENST00000382871.2
ZMYM2
zinc finger, MYM-type 2
chr17_+_19314432 0.33 ENST00000575165.2
RNF112
ring finger protein 112
chr2_+_201171577 0.33 ENST00000409397.2
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr19_-_23578220 0.33 ENST00000595533.1
ENST00000397082.2
ENST00000599743.1
ENST00000300619.7
ZNF91
zinc finger protein 91
chr5_+_43602750 0.33 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT
nicotinamide nucleotide transhydrogenase
chr17_-_39526052 0.33 ENST00000251646.3
KRT33B
keratin 33B
chr1_+_6845497 0.33 ENST00000473578.1
ENST00000557126.1
CAMTA1
calmodulin binding transcription activator 1
chr5_-_89705537 0.33 ENST00000522864.1
ENST00000522083.1
ENST00000522565.1
ENST00000522842.1
ENST00000283122.3
CETN3
centrin, EF-hand protein, 3
chr2_+_201170999 0.33 ENST00000439395.1
ENST00000444012.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr4_+_52709229 0.33 ENST00000334635.5
ENST00000381441.3
ENST00000381437.4
DCUN1D4
DCN1, defective in cullin neddylation 1, domain containing 4
chr17_-_57232525 0.33 ENST00000583380.1
ENST00000580541.1
ENST00000578105.1
ENST00000437036.2
SKA2
spindle and kinetochore associated complex subunit 2
chr13_-_31191642 0.33 ENST00000405805.1
HMGB1
high mobility group box 1
chr9_-_99180597 0.32 ENST00000375256.4
ZNF367
zinc finger protein 367
chr2_+_20646824 0.32 ENST00000272233.4
RHOB
ras homolog family member B
chr16_-_14788526 0.32 ENST00000438167.3
PLA2G10
phospholipase A2, group X
chr18_-_19284724 0.32 ENST00000580981.1
ENST00000289119.2
ABHD3
abhydrolase domain containing 3
chr1_+_33283043 0.32 ENST00000373476.1
ENST00000373475.5
ENST00000529027.1
ENST00000398243.3
S100PBP
S100P binding protein
chr2_+_14772810 0.32 ENST00000295092.2
ENST00000331243.4
FAM84A
family with sequence similarity 84, member A
chr16_+_89238149 0.32 ENST00000289746.2
CDH15
cadherin 15, type 1, M-cadherin (myotubule)
chr8_-_22014339 0.32 ENST00000306317.2
LGI3
leucine-rich repeat LGI family, member 3
chr13_-_41240717 0.32 ENST00000379561.5
FOXO1
forkhead box O1
chr11_-_14913190 0.32 ENST00000532378.1
CYP2R1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr1_-_247267580 0.32 ENST00000366501.1
ENST00000366500.1
ENST00000476158.2
ENST00000448299.2
ENST00000358785.4
ENST00000343381.6
ZNF669
zinc finger protein 669
chr10_+_5090940 0.32 ENST00000602997.1
AKR1C3
aldo-keto reductase family 1, member C3
chrX_-_80377162 0.31 ENST00000430960.1
ENST00000447319.1
HMGN5
high mobility group nucleosome binding domain 5
chr10_+_89622870 0.31 ENST00000371953.3
PTEN
phosphatase and tensin homolog
chr5_-_2751762 0.31 ENST00000302057.5
ENST00000382611.6
IRX2
iroquois homeobox 2
chr19_-_59084647 0.31 ENST00000594234.1
ENST00000596039.1
MZF1
myeloid zinc finger 1
chr13_-_31736478 0.31 ENST00000445273.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr13_+_20532848 0.31 ENST00000382874.2
ZMYM2
zinc finger, MYM-type 2
chr2_+_201171268 0.31 ENST00000423749.1
ENST00000428692.1
ENST00000457757.1
ENST00000453663.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr7_+_64254766 0.31 ENST00000307355.7
ENST00000359735.3
ZNF138
zinc finger protein 138
chr1_-_200379180 0.30 ENST00000294740.3
ZNF281
zinc finger protein 281
chr19_+_16435625 0.30 ENST00000248071.5
ENST00000592003.1
KLF2
Kruppel-like factor 2
chr14_+_64970427 0.30 ENST00000553583.1
ZBTB1
zinc finger and BTB domain containing 1
chr2_-_40006289 0.30 ENST00000260619.6
ENST00000454352.2
THUMPD2
THUMP domain containing 2
chr1_-_935491 0.30 ENST00000304952.6
HES4
hes family bHLH transcription factor 4
chrX_-_117119243 0.30 ENST00000539496.1
ENST00000469946.1
KLHL13
kelch-like family member 13
chr5_+_59783540 0.29 ENST00000515734.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr5_+_78532003 0.29 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chrX_-_153210107 0.29 ENST00000369997.3
ENST00000393700.3
ENST00000412763.1
RENBP
renin binding protein
chr18_+_596982 0.29 ENST00000579912.1
ENST00000400606.2
ENST00000540035.1
CLUL1
clusterin-like 1 (retinal)
chr19_-_12405689 0.29 ENST00000355684.5
ZNF44
zinc finger protein 44
chr6_-_116989916 0.29 ENST00000368576.3
ENST00000368573.1
ZUFSP
zinc finger with UFM1-specific peptidase domain
chr10_+_89264625 0.28 ENST00000371996.4
ENST00000371994.4
MINPP1
multiple inositol-polyphosphate phosphatase 1
chr12_+_58138664 0.28 ENST00000257910.3
TSPAN31
tetraspanin 31
chr4_-_175204765 0.28 ENST00000513696.1
ENST00000503293.1
FBXO8
F-box protein 8
chr8_-_93978357 0.28 ENST00000522925.1
ENST00000522903.1
ENST00000537541.1
ENST00000518748.1
ENST00000519069.1
ENST00000521988.1
TRIQK
triple QxxK/R motif containing
chr9_+_32566787 0.28 ENST00000451672.1
GVQW1
GVQW motif containing 1
chr8_-_41166953 0.28 ENST00000220772.3
SFRP1
secreted frizzled-related protein 1
chrX_-_72434628 0.28 ENST00000536638.1
ENST00000373517.3
NAP1L2
nucleosome assembly protein 1-like 2
chr14_-_100046444 0.28 ENST00000554996.1
CCDC85C
coiled-coil domain containing 85C
chr16_+_55690002 0.27 ENST00000414754.3
SLC6A2
solute carrier family 6 (neurotransmitter transporter), member 2
chr9_-_33264676 0.27 ENST00000472232.3
ENST00000379704.2
BAG1
BCL2-associated athanogene
chr9_-_98079154 0.27 ENST00000433829.1
FANCC
Fanconi anemia, complementation group C
chr5_-_81046922 0.27 ENST00000514493.1
ENST00000320672.4
SSBP2
single-stranded DNA binding protein 2
chr12_-_57914275 0.27 ENST00000547303.1
ENST00000552740.1
ENST00000547526.1
ENST00000551116.1
ENST00000346473.3
DDIT3
DNA-damage-inducible transcript 3
chr20_+_43343476 0.27 ENST00000372868.2
WISP2
WNT1 inducible signaling pathway protein 2
chr11_-_105892937 0.27 ENST00000301919.4
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
MSANTD4
Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
chrX_-_132549506 0.26 ENST00000370828.3
GPC4
glypican 4
chr2_+_66662690 0.26 ENST00000488550.1
MEIS1
Meis homeobox 1
chr7_-_64467031 0.26 ENST00000394323.2
ERV3-1
endogenous retrovirus group 3, member 1
chr19_+_21265028 0.26 ENST00000291770.7
ZNF714
zinc finger protein 714
chr12_-_91573132 0.26 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr6_+_10723148 0.26 ENST00000541412.1
ENST00000229563.5
TMEM14C
transmembrane protein 14C

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0061290 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.2 0.5 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) positive regulation of mitochondrial DNA metabolic process(GO:1901860) response to methionine(GO:1904640)
0.2 1.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 0.7 GO:0070893 transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895)
0.2 0.5 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.2 0.5 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.2 0.6 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.1 0.4 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.1 0.8 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.1 0.4 GO:0072560 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.1 0.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1 1.2 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.3 GO:2000224 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.1 0.3 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.1 0.3 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.1 0.4 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.3 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 0.6 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.8 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 0.4 GO:0060971 intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) embryonic heart tube left/right pattern formation(GO:0060971)
0.1 0.3 GO:0035711 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711)
0.1 0.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.6 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.3 GO:1903984 negative regulation of ribosome biogenesis(GO:0090071) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.2 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 0.2 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.3 GO:0002572 pro-T cell differentiation(GO:0002572) regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.1 1.4 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 0.5 GO:0070417 cellular response to cold(GO:0070417)
0.1 0.4 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.4 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 1.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.3 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.1 0.2 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.3 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 0.3 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.1 0.2 GO:0042361 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.1 0.5 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.1 1.0 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.4 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.1 0.4 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.2 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.3 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.2 GO:2000690 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.4 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.3 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.1 GO:1904976 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.0 0.7 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.4 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.8 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.3 GO:1903751 intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481) regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.0 0.5 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.3 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.1 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.3 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.3 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.8 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.1 GO:0010160 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.0 0.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0 1.0 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.5 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 1.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.0 0.2 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.3 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.6 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.2 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.3 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.6 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.4 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.1 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.4 GO:0045651 positive regulation of macrophage differentiation(GO:0045651) positive regulation of monocyte differentiation(GO:0045657)
0.0 0.3 GO:0051934 dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0 0.5 GO:0016180 snRNA processing(GO:0016180)
0.0 0.7 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.2 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.4 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.7 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.5 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.4 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.1 GO:0009804 coumarin metabolic process(GO:0009804) biphenyl catabolic process(GO:0070980)
0.0 0.3 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.5 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:1903416 response to glycoside(GO:1903416)
0.0 0.4 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.1 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.2 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.0 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.4 GO:0060187 cell pole(GO:0060187)
0.1 1.4 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.3 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.3 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.1 0.2 GO:0044308 axonal spine(GO:0044308)
0.1 0.4 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.4 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 1.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.5 GO:0070695 FHF complex(GO:0070695)
0.1 0.3 GO:0036338 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.7 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.5 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0033269 internode region of axon(GO:0033269)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0097196 Shu complex(GO:0097196)
0.0 0.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.1 GO:0097637 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.5 GO:0097440 apical dendrite(GO:0097440)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.3 GO:0071682 endocytic vesicle lumen(GO:0071682)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.2 0.8 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.2 0.6 GO:0035939 microsatellite binding(GO:0035939)
0.2 0.6 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.2 0.5 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.3 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.1 0.3 GO:0047017 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.1 1.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.3 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.1 0.3 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 1.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.3 GO:0019808 polyamine binding(GO:0019808)
0.1 0.3 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.1 0.5 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 0.2 GO:0052857 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.1 0.3 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 1.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.3 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.2 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.3 GO:0005334 norepinephrine:sodium symporter activity(GO:0005334)
0.1 0.3 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.5 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.8 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.4 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.8 GO:0008430 selenium binding(GO:0008430)
0.0 0.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 1.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0045142 triplex DNA binding(GO:0045142)
0.0 0.4 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.3 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.4 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.3 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 1.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.3 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.0 GO:0030984 kininogen binding(GO:0030984)
0.0 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.6 GO:0030332 cyclin binding(GO:0030332)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.2 PID FOXO PATHWAY FoxO family signaling
0.0 1.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.5 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.5 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 1.0 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.5 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.9 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.6 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 7.4 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway