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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PBX1

Z-value: 0.68

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Transcription factors associated with PBX1

Gene Symbol Gene ID Gene Info
PBX1
ENSG00000185630.14 PBX homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PBX1hg19_v2_chr1_+_164600184_164600218-0.503.1e-01Click!

Activity profile of PBX1 motif

Sorted Z-values of PBX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_50981079 0.68 ENST00000609268.1
CTA-384D8.34
CTA-384D8.34
chr22_-_30642728 0.60 ENST00000403987.3
LIF
leukemia inhibitory factor
chr6_-_26250835 0.60 ENST00000446824.2
HIST1H3F
histone cluster 1, H3f
chr6_+_27775899 0.37 ENST00000358739.3
HIST1H2AI
histone cluster 1, H2ai
chr22_-_30642782 0.37 ENST00000249075.3
LIF
leukemia inhibitory factor
chr22_+_29138013 0.31 ENST00000216027.3
ENST00000398941.2
HSCB
HscB mitochondrial iron-sulfur cluster co-chaperone
chr9_+_140135665 0.30 ENST00000340384.4
TUBB4B
tubulin, beta 4B class IVb
chr14_-_24584138 0.27 ENST00000558280.1
ENST00000561028.1
NRL
neural retina leucine zipper
chr2_+_234104079 0.25 ENST00000417661.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr6_+_26199737 0.25 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr16_-_88729473 0.23 ENST00000301012.3
ENST00000569177.1
MVD
mevalonate (diphospho) decarboxylase
chr19_-_5903714 0.22 ENST00000586349.1
ENST00000585661.1
ENST00000308961.4
ENST00000592634.1
ENST00000418389.2
ENST00000252675.5
AC024592.12
NDUFA11
FUT5
Uncharacterized protein
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr11_+_64794991 0.22 ENST00000352068.5
ENST00000525648.1
SNX15
sorting nexin 15
chr10_-_18948208 0.21 ENST00000607346.1
ARL5B-AS1
ARL5B antisense RNA 1
chr14_+_50065459 0.21 ENST00000318317.4
LRR1
leucine rich repeat protein 1
chr16_-_20702578 0.20 ENST00000307493.4
ENST00000219151.4
ACSM1
acyl-CoA synthetase medium-chain family member 1
chr19_+_46498704 0.20 ENST00000595358.1
ENST00000594672.1
ENST00000536603.1
CCDC61
coiled-coil domain containing 61
chr3_+_193853927 0.20 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr10_+_51549498 0.20 ENST00000358559.2
ENST00000298239.6
MSMB
microseminoprotein, beta-
chr6_-_26032288 0.19 ENST00000244661.2
HIST1H3B
histone cluster 1, H3b
chr19_-_49121054 0.19 ENST00000546623.1
ENST00000084795.5
RPL18
ribosomal protein L18
chr4_-_105416039 0.19 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr4_-_69536346 0.18 ENST00000338206.5
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr12_-_53207842 0.18 ENST00000458244.2
KRT4
keratin 4
chr10_+_90484301 0.18 ENST00000404190.1
LIPK
lipase, family member K
chr6_-_26124138 0.18 ENST00000314332.5
ENST00000396984.1
HIST1H2BC
histone cluster 1, H2bc
chr3_+_52570610 0.18 ENST00000307106.3
ENST00000477703.1
ENST00000476842.1
SMIM4
small integral membrane protein 4
chr12_-_106477805 0.18 ENST00000553094.1
ENST00000549704.1
NUAK1
NUAK family, SNF1-like kinase, 1
chr9_-_32573130 0.18 ENST00000350021.2
ENST00000379847.3
NDUFB6
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
chrX_+_109602039 0.18 ENST00000520821.1
RGAG1
retrotransposon gag domain containing 1
chr7_+_120629653 0.17 ENST00000450913.2
ENST00000340646.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr16_-_838329 0.17 ENST00000563560.1
ENST00000569601.1
ENST00000565809.1
ENST00000565377.1
ENST00000007264.2
ENST00000567114.1
RPUSD1
RNA pseudouridylate synthase domain containing 1
chr5_+_159656437 0.17 ENST00000402432.3
FABP6
fatty acid binding protein 6, ileal
chrX_+_125953746 0.17 ENST00000371125.3
CXorf64
chromosome X open reading frame 64
chr12_+_81471816 0.17 ENST00000261206.3
ACSS3
acyl-CoA synthetase short-chain family member 3
chr7_-_27142290 0.17 ENST00000222718.5
HOXA2
homeobox A2
chr5_+_3596168 0.16 ENST00000302006.3
IRX1
iroquois homeobox 1
chr19_-_49955050 0.15 ENST00000262265.5
PIH1D1
PIH1 domain containing 1
chr19_+_10828724 0.15 ENST00000585892.1
ENST00000314646.5
ENST00000359692.6
DNM2
dynamin 2
chr6_-_26199499 0.15 ENST00000377831.5
HIST1H3D
histone cluster 1, H3d
chr3_-_112564797 0.15 ENST00000398214.1
ENST00000448932.1
CD200R1L
CD200 receptor 1-like
chr11_+_114166536 0.14 ENST00000299964.3
NNMT
nicotinamide N-methyltransferase
chr2_+_12857015 0.14 ENST00000155926.4
TRIB2
tribbles pseudokinase 2
chr10_+_69865866 0.14 ENST00000354393.2
MYPN
myopalladin
chr11_-_2162162 0.14 ENST00000381389.1
IGF2
insulin-like growth factor 2 (somatomedin A)
chr10_+_69869237 0.13 ENST00000373675.3
MYPN
myopalladin
chr2_+_12857043 0.13 ENST00000381465.2
TRIB2
tribbles pseudokinase 2
chr9_-_131486367 0.13 ENST00000372663.4
ENST00000406904.2
ENST00000452105.1
ENST00000372672.2
ENST00000372667.5
ZDHHC12
zinc finger, DHHC-type containing 12
chr14_-_64971893 0.13 ENST00000555220.1
ZBTB25
zinc finger and BTB domain containing 25
chr6_-_110736742 0.13 ENST00000368924.3
ENST00000368923.3
DDO
D-aspartate oxidase
chr15_-_60683326 0.13 ENST00000559350.1
ENST00000558986.1
ENST00000560389.1
ANXA2
annexin A2
chr4_+_77356248 0.12 ENST00000296043.6
SHROOM3
shroom family member 3
chr5_-_141703713 0.12 ENST00000511815.1
SPRY4
sprouty homolog 4 (Drosophila)
chr7_+_134331550 0.12 ENST00000344924.3
ENST00000418040.1
ENST00000393132.2
BPGM
2,3-bisphosphoglycerate mutase
chr19_+_19030478 0.12 ENST00000247003.4
DDX49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr19_-_11266437 0.12 ENST00000586708.1
ENST00000591396.1
ENST00000592967.1
ENST00000585486.1
ENST00000585567.1
SPC24
SPC24, NDC80 kinetochore complex component
chr11_+_844406 0.12 ENST00000397404.1
TSPAN4
tetraspanin 4
chr10_+_124320195 0.12 ENST00000359586.6
DMBT1
deleted in malignant brain tumors 1
chr16_-_63651939 0.12 ENST00000563855.1
ENST00000568932.1
ENST00000564290.1
RP11-368L12.1
RP11-368L12.1
chr19_+_41698927 0.12 ENST00000310054.4
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr2_+_219110149 0.12 ENST00000456575.1
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr12_+_48722763 0.11 ENST00000335017.1
H1FNT
H1 histone family, member N, testis-specific
chr11_-_118966167 0.11 ENST00000530167.1
H2AFX
H2A histone family, member X
chr17_-_15519008 0.11 ENST00000261644.8
CDRT1
CMT1A duplicated region transcript 1
chr12_-_91573249 0.11 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN
decorin
chr6_-_36725157 0.11 ENST00000393189.2
CPNE5
copine V
chrX_+_1734051 0.11 ENST00000381229.4
ENST00000381233.3
ASMT
acetylserotonin O-methyltransferase
chr19_+_19030497 0.11 ENST00000438170.2
DDX49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr2_+_62132800 0.11 ENST00000538736.1
COMMD1
copper metabolism (Murr1) domain containing 1
chr14_+_23709555 0.10 ENST00000430154.2
C14orf164
chromosome 14 open reading frame 164
chr11_+_44117219 0.10 ENST00000532479.1
ENST00000527014.1
EXT2
exostosin glycosyltransferase 2
chr8_-_91095099 0.10 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr6_-_167040731 0.10 ENST00000265678.4
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr1_+_205473720 0.10 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
CDK18
cyclin-dependent kinase 18
chr3_-_71114066 0.10 ENST00000485326.2
FOXP1
forkhead box P1
chr14_+_50065376 0.10 ENST00000298288.6
LRR1
leucine rich repeat protein 1
chr2_-_190044480 0.10 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chrX_-_1331527 0.10 ENST00000381567.3
ENST00000381566.1
ENST00000400841.2
CRLF2
cytokine receptor-like factor 2
chrX_+_140084756 0.10 ENST00000449283.1
SPANXB2
SPANX family, member B2
chr9_-_14308004 0.10 ENST00000493697.1
NFIB
nuclear factor I/B
chr18_-_56985776 0.09 ENST00000587244.1
CPLX4
complexin 4
chr15_-_44069513 0.09 ENST00000433927.1
ELL3
elongation factor RNA polymerase II-like 3
chr18_+_44526786 0.09 ENST00000245121.5
ENST00000356157.7
KATNAL2
katanin p60 subunit A-like 2
chr4_+_187148556 0.09 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr1_-_3713042 0.09 ENST00000378251.1
LRRC47
leucine rich repeat containing 47
chr15_+_44069276 0.09 ENST00000381359.1
SERF2
small EDRK-rich factor 2
chr17_+_8191815 0.09 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RANGRF
RAN guanine nucleotide release factor
chr7_-_102184083 0.09 ENST00000379357.5
POLR2J3
polymerase (RNA) II (DNA directed) polypeptide J3
chr8_-_37411648 0.09 ENST00000519738.1
RP11-150O12.1
RP11-150O12.1
chrX_+_139791917 0.09 ENST00000607004.1
ENST00000370535.3
LINC00632
long intergenic non-protein coding RNA 632
chr19_+_49999631 0.08 ENST00000270625.2
ENST00000596873.1
ENST00000594493.1
ENST00000599561.1
RPS11
ribosomal protein S11
chr7_-_559853 0.08 ENST00000405692.2
PDGFA
platelet-derived growth factor alpha polypeptide
chr17_+_72983674 0.08 ENST00000337231.5
CDR2L
cerebellar degeneration-related protein 2-like
chr21_+_39668478 0.08 ENST00000398927.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr2_+_201997595 0.08 ENST00000470178.2
CFLAR
CASP8 and FADD-like apoptosis regulator
chr19_+_12203100 0.08 ENST00000596883.1
ZNF788
zinc finger family member 788
chr3_-_161090660 0.08 ENST00000359175.4
SPTSSB
serine palmitoyltransferase, small subunit B
chr7_-_72971934 0.08 ENST00000411832.1
BCL7B
B-cell CLL/lymphoma 7B
chr20_-_45976816 0.07 ENST00000441977.1
ZMYND8
zinc finger, MYND-type containing 8
chr17_-_40828969 0.07 ENST00000591022.1
ENST00000587627.1
ENST00000293349.6
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chrM_+_10053 0.07 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chr6_-_167040693 0.07 ENST00000366863.2
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr22_-_22337146 0.07 ENST00000398793.2
TOP3B
topoisomerase (DNA) III beta
chr8_+_99076750 0.07 ENST00000545282.1
C8orf47
chromosome 8 open reading frame 47
chr19_-_39881669 0.07 ENST00000221266.7
PAF1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr11_-_32816156 0.07 ENST00000531481.1
ENST00000335185.5
CCDC73
coiled-coil domain containing 73
chr19_+_782755 0.07 ENST00000606242.1
ENST00000586061.1
AC006273.5
AC006273.5
chr22_+_35695793 0.07 ENST00000456128.1
ENST00000449058.2
ENST00000411850.1
ENST00000425375.1
ENST00000436462.2
ENST00000382034.5
TOM1
target of myb1 (chicken)
chr18_-_14132422 0.07 ENST00000589498.1
ENST00000590202.1
ZNF519
zinc finger protein 519
chr11_+_61717279 0.07 ENST00000378043.4
BEST1
bestrophin 1
chr6_+_151561085 0.07 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr1_-_206288647 0.07 ENST00000331555.5
C1orf186
chromosome 1 open reading frame 186
chr19_+_5681153 0.07 ENST00000579559.1
ENST00000577222.1
HSD11B1L
RPL36
hydroxysteroid (11-beta) dehydrogenase 1-like
ribosomal protein L36
chr5_+_166711804 0.07 ENST00000518659.1
ENST00000545108.1
TENM2
teneurin transmembrane protein 2
chr3_-_149510553 0.07 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ANKUB1
ankyrin repeat and ubiquitin domain containing 1
chr22_-_22337204 0.06 ENST00000430142.1
ENST00000357179.5
TOP3B
topoisomerase (DNA) III beta
chr17_+_78518617 0.06 ENST00000537330.1
ENST00000570891.1
RPTOR
regulatory associated protein of MTOR, complex 1
chr11_+_61717336 0.06 ENST00000378042.3
BEST1
bestrophin 1
chr5_-_171881362 0.06 ENST00000519643.1
SH3PXD2B
SH3 and PX domains 2B
chr6_-_27114577 0.06 ENST00000356950.1
ENST00000396891.4
HIST1H2BK
histone cluster 1, H2bk
chr4_-_57844989 0.06 ENST00000264230.4
NOA1
nitric oxide associated 1
chr9_-_123676827 0.06 ENST00000546084.1
TRAF1
TNF receptor-associated factor 1
chr11_-_126870655 0.06 ENST00000525144.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr4_-_185776789 0.06 ENST00000510284.1
RP11-701P16.5
RP11-701P16.5
chr10_+_24738355 0.06 ENST00000307544.6
KIAA1217
KIAA1217
chr16_+_19078911 0.06 ENST00000321998.5
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chrX_+_53123314 0.06 ENST00000605526.1
ENST00000604062.1
ENST00000604369.1
ENST00000366185.2
ENST00000604849.1
RP11-258C19.5
long intergenic non-protein coding RNA 1155
chr3_-_178103144 0.06 ENST00000417383.1
ENST00000418585.1
ENST00000411727.1
ENST00000439810.1
RP11-33A14.1
RP11-33A14.1
chr11_-_34938039 0.06 ENST00000395787.3
APIP
APAF1 interacting protein
chr5_+_98109322 0.06 ENST00000513185.1
RGMB
repulsive guidance molecule family member b
chr1_-_54405773 0.06 ENST00000371376.1
HSPB11
heat shock protein family B (small), member 11
chr1_-_28241226 0.06 ENST00000373912.3
ENST00000373909.3
RPA2
replication protein A2, 32kDa
chr17_+_21030260 0.06 ENST00000579303.1
DHRS7B
dehydrogenase/reductase (SDR family) member 7B
chr17_+_7328925 0.06 ENST00000333870.3
ENST00000574034.1
C17orf74
chromosome 17 open reading frame 74
chr12_-_121342170 0.06 ENST00000353487.2
SPPL3
signal peptide peptidase like 3
chr7_+_80275953 0.06 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36
CD36 molecule (thrombospondin receptor)
chrX_-_110655306 0.05 ENST00000371993.2
DCX
doublecortin
chr3_-_12587055 0.05 ENST00000564146.3
C3orf83
chromosome 3 open reading frame 83
chr12_-_95510743 0.05 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr9_+_130565147 0.05 ENST00000373247.2
ENST00000373245.1
ENST00000393706.2
ENST00000373228.1
FPGS
folylpolyglutamate synthase
chr17_-_40829026 0.05 ENST00000412503.1
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr3_-_71353892 0.05 ENST00000484350.1
FOXP1
forkhead box P1
chr12_+_12870055 0.05 ENST00000228872.4
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr3_+_179280668 0.05 ENST00000429709.2
ENST00000450518.2
ENST00000392662.1
ENST00000490364.1
ACTL6A
actin-like 6A
chr13_+_74805561 0.05 ENST00000419499.1
LINC00402
long intergenic non-protein coding RNA 402
chr4_-_186570679 0.05 ENST00000451974.1
SORBS2
sorbin and SH3 domain containing 2
chr14_+_104182061 0.05 ENST00000216602.6
ZFYVE21
zinc finger, FYVE domain containing 21
chr16_-_29499154 0.05 ENST00000354563.5
RP11-231C14.4
Uncharacterized protein
chr11_+_66384053 0.05 ENST00000310137.4
ENST00000393979.3
ENST00000409372.1
ENST00000443702.1
ENST00000409738.4
ENST00000514361.3
ENST00000503028.2
ENST00000412278.2
ENST00000500635.2
RBM14
RBM4
RBM14-RBM4
RNA binding motif protein 14
RNA binding motif protein 4
RBM14-RBM4 readthrough
chr12_-_56615485 0.05 ENST00000549038.1
ENST00000552244.1
RNF41
ring finger protein 41
chr8_+_98788057 0.05 ENST00000517924.1
LAPTM4B
lysosomal protein transmembrane 4 beta
chr14_-_74551172 0.05 ENST00000553458.1
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chrX_-_92928557 0.05 ENST00000373079.3
ENST00000475430.2
NAP1L3
nucleosome assembly protein 1-like 3
chr18_-_48346415 0.05 ENST00000431965.2
ENST00000436348.2
MRO
maestro
chr7_+_80275752 0.05 ENST00000419819.2
CD36
CD36 molecule (thrombospondin receptor)
chr17_+_73663402 0.05 ENST00000355423.3
SAP30BP
SAP30 binding protein
chr12_-_56615693 0.05 ENST00000394013.2
ENST00000345093.4
ENST00000551711.1
ENST00000552656.1
RNF41
ring finger protein 41
chr14_+_29236269 0.05 ENST00000313071.4
FOXG1
forkhead box G1
chr19_+_14640372 0.05 ENST00000215567.5
ENST00000598298.1
ENST00000596073.1
ENST00000600083.1
ENST00000436007.2
TECR
trans-2,3-enoyl-CoA reductase
chrX_+_55649833 0.05 ENST00000339140.3
FOXR2
forkhead box R2
chr15_-_54025300 0.05 ENST00000559418.1
WDR72
WD repeat domain 72
chr19_-_11266471 0.05 ENST00000592540.1
SPC24
SPC24, NDC80 kinetochore complex component
chr15_-_60695071 0.05 ENST00000557904.1
ANXA2
annexin A2
chr16_+_19222479 0.04 ENST00000568433.1
SYT17
synaptotagmin XVII
chr5_+_140207536 0.04 ENST00000529310.1
ENST00000527624.1
PCDHA6
protocadherin alpha 6
chr16_-_69788816 0.04 ENST00000268802.5
NOB1
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr12_+_101988627 0.04 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1
myosin binding protein C, slow type
chr3_-_4927447 0.04 ENST00000449914.1
AC018816.3
Uncharacterized protein
chr6_-_26199471 0.04 ENST00000341023.1
HIST1H2AD
histone cluster 1, H2ad
chr11_+_44117099 0.04 ENST00000533608.1
EXT2
exostosin glycosyltransferase 2
chr4_-_184241927 0.04 ENST00000323319.5
CLDN22
claudin 22
chr11_+_47279155 0.04 ENST00000444396.1
ENST00000457932.1
ENST00000412937.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr14_+_24584372 0.04 ENST00000559396.1
ENST00000558638.1
ENST00000561041.1
ENST00000559288.1
ENST00000558408.1
DCAF11
DDB1 and CUL4 associated factor 11
chr3_+_122785895 0.04 ENST00000316218.7
PDIA5
protein disulfide isomerase family A, member 5
chr17_+_7758374 0.04 ENST00000301599.6
ENST00000574668.1
TMEM88
transmembrane protein 88
chr4_-_6557336 0.04 ENST00000507294.1
PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma
chr12_-_109221160 0.04 ENST00000326470.5
SSH1
slingshot protein phosphatase 1
chr5_+_151151471 0.04 ENST00000394123.3
ENST00000543466.1
G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr12_+_101988774 0.04 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
MYBPC1
myosin binding protein C, slow type
chr19_-_44306590 0.04 ENST00000377950.3
LYPD5
LY6/PLAUR domain containing 5
chr10_-_91102410 0.04 ENST00000282673.4
LIPA
lipase A, lysosomal acid, cholesterol esterase
chr1_-_173176452 0.04 ENST00000281834.3
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr7_+_20370746 0.04 ENST00000222573.4
ITGB8
integrin, beta 8
chr22_+_31795509 0.04 ENST00000331457.4
DRG1
developmentally regulated GTP binding protein 1
chr4_-_73434498 0.04 ENST00000286657.4
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr8_-_6115044 0.04 ENST00000519555.1
RP11-124B13.1
RP11-124B13.1
chr2_-_242626127 0.04 ENST00000445261.1
DTYMK
deoxythymidylate kinase (thymidylate kinase)
chr7_+_75024903 0.03 ENST00000323819.3
ENST00000430211.1
TRIM73
tripartite motif containing 73
chr19_-_39881777 0.03 ENST00000595564.1
ENST00000221265.3
PAF1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr19_-_14640005 0.03 ENST00000596853.1
ENST00000596075.1
ENST00000595992.1
ENST00000396969.4
ENST00000601533.1
ENST00000598692.1
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr6_+_151561506 0.03 ENST00000253332.1
AKAP12
A kinase (PRKA) anchor protein 12
chr8_-_116681221 0.03 ENST00000395715.3
TRPS1
trichorhinophalangeal syndrome I
chr2_-_96971232 0.03 ENST00000323853.5
SNRNP200
small nuclear ribonucleoprotein 200kDa (U5)
chr3_+_129159039 0.03 ENST00000507564.1
ENST00000431818.2
ENST00000504021.1
ENST00000349441.2
ENST00000348417.2
ENST00000440957.2
IFT122
intraflagellar transport 122 homolog (Chlamydomonas)
chr9_+_130565487 0.03 ENST00000373225.3
ENST00000431857.1
FPGS
folylpolyglutamate synthase
chr2_+_79412357 0.03 ENST00000466387.1
CTNNA2
catenin (cadherin-associated protein), alpha 2
chr8_+_7801144 0.03 ENST00000443676.1
ZNF705B
zinc finger protein 705B
chrM_+_14741 0.03 ENST00000361789.2
MT-CYB
mitochondrially encoded cytochrome b
chr12_+_123944070 0.03 ENST00000412157.2
SNRNP35
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr6_+_36839616 0.03 ENST00000359359.2
ENST00000510325.2
C6orf89
chromosome 6 open reading frame 89

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.3 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.1 0.3 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.2 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 0.3 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.2 GO:2000974 negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.2 GO:0021569 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.2 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.0 0.1 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:0052362 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.2 GO:1903939 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.0 0.1 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0072025 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
0.0 0.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.1 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.2 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.2 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.2 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0007320 insemination(GO:0007320)
0.0 0.0 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.1 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.0 GO:2000525 negative regulation of regulatory T cell differentiation(GO:0045590) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.0 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.2 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.0 GO:0034686 integrin alphav-beta8 complex(GO:0034686)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.3 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.2 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.1 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.1 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.0 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0032052 bile acid binding(GO:0032052)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.0 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening