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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PAX8

Z-value: 0.84

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Transcription factors associated with PAX8

Gene Symbol Gene ID Gene Info
PAX8
ENSG00000125618.12 paired box 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX8hg19_v2_chr2_-_114036488_1140365270.612.0e-01Click!

Activity profile of PAX8 motif

Sorted Z-values of PAX8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_92821922 1.08 ENST00000538965.1
ENST00000378487.2
CLLU1OS
chronic lymphocytic leukemia up-regulated 1 opposite strand
chr1_-_153013588 1.06 ENST00000360379.3
SPRR2D
small proline-rich protein 2D
chrX_-_153141783 0.77 ENST00000458029.1
L1CAM
L1 cell adhesion molecule
chr12_+_72058130 0.64 ENST00000547843.1
THAP2
THAP domain containing, apoptosis associated protein 2
chr2_-_37068530 0.62 ENST00000593798.1
AC007382.1
Uncharacterized protein
chr11_-_105010320 0.43 ENST00000532895.1
ENST00000530950.1
CARD18
caspase recruitment domain family, member 18
chr6_+_8652370 0.43 ENST00000503668.1
HULC
hepatocellular carcinoma up-regulated long non-coding RNA
chr10_+_12391685 0.42 ENST00000378845.1
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr14_-_57197224 0.38 ENST00000554597.1
ENST00000556696.1
RP11-1085N6.3
Uncharacterized protein
chr1_+_218683438 0.37 ENST00000443836.1
C1orf143
chromosome 1 open reading frame 143
chr12_+_7167980 0.37 ENST00000360817.5
ENST00000402681.3
C1S
complement component 1, s subcomponent
chr3_-_110612323 0.34 ENST00000383686.2
RP11-553A10.1
Uncharacterized protein
chrX_-_84363974 0.32 ENST00000395409.3
ENST00000332921.5
ENST00000509231.1
SATL1
spermidine/spermine N1-acetyl transferase-like 1
chr10_+_135340859 0.32 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr9_-_117853297 0.30 ENST00000542877.1
ENST00000537320.1
ENST00000341037.4
TNC
tenascin C
chr6_-_6711235 0.29 ENST00000432823.2
RP1-80N2.2
RP1-80N2.2
chr4_+_123653882 0.29 ENST00000433287.1
BBS12
Bardet-Biedl syndrome 12
chr1_-_52520828 0.28 ENST00000610127.1
TXNDC12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr17_-_73267214 0.28 ENST00000580717.1
ENST00000577542.1
ENST00000579612.1
ENST00000245551.5
MIF4GD
MIF4G domain containing
chr22_-_44258280 0.28 ENST00000540422.1
SULT4A1
sulfotransferase family 4A, member 1
chr11_-_9482010 0.26 ENST00000596206.1
AC132192.1
LOC644656 protein; Uncharacterized protein
chr17_+_7462103 0.26 ENST00000396545.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr6_+_24126350 0.26 ENST00000378491.4
ENST00000378478.1
ENST00000378477.2
NRSN1
neurensin 1
chr17_-_73267304 0.25 ENST00000579297.1
ENST00000580571.1
MIF4GD
MIF4G domain containing
chr17_-_73267281 0.24 ENST00000578305.1
ENST00000325102.8
MIF4GD
MIF4G domain containing
chr6_-_44233361 0.24 ENST00000275015.5
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr19_+_34891252 0.24 ENST00000606020.1
RP11-618P17.4
Uncharacterized protein
chr1_-_119682812 0.23 ENST00000537870.1
WARS2
tryptophanyl tRNA synthetase 2, mitochondrial
chr17_+_7461613 0.23 ENST00000438470.1
ENST00000436057.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr19_+_35417939 0.23 ENST00000601142.1
ENST00000426813.2
ZNF30
zinc finger protein 30
chr19_+_42041860 0.22 ENST00000483481.2
ENST00000494375.2
AC006129.4
AC006129.4
chr19_-_55791563 0.21 ENST00000588971.1
ENST00000255631.5
ENST00000587551.1
HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr17_+_7461580 0.21 ENST00000483039.1
ENST00000396542.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr12_-_123201337 0.21 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr11_-_102401469 0.21 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr2_-_106013207 0.20 ENST00000447958.1
FHL2
four and a half LIM domains 2
chr20_-_36794938 0.20 ENST00000453095.1
TGM2
transglutaminase 2
chr13_-_24471194 0.20 ENST00000382137.3
ENST00000382057.3
C1QTNF9B
C1q and tumor necrosis factor related protein 9B
chr19_+_782755 0.19 ENST00000606242.1
ENST00000586061.1
AC006273.5
AC006273.5
chr12_-_86650077 0.19 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr15_+_67420441 0.19 ENST00000558894.1
SMAD3
SMAD family member 3
chr6_+_43739697 0.19 ENST00000230480.6
VEGFA
vascular endothelial growth factor A
chr6_-_134639180 0.18 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr21_-_44582378 0.18 ENST00000433840.1
AP001631.10
AP001631.10
chr13_+_31309645 0.18 ENST00000380490.3
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr1_-_182573514 0.17 ENST00000367558.5
RGS16
regulator of G-protein signaling 16
chr7_+_129984630 0.17 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
CPA5
carboxypeptidase A5
chr14_+_75230011 0.17 ENST00000552421.1
ENST00000325680.7
ENST00000238571.3
YLPM1
YLP motif containing 1
chr11_-_2170786 0.17 ENST00000300632.5
IGF2
insulin-like growth factor 2 (somatomedin A)
chr11_+_59705928 0.16 ENST00000398992.1
OOSP1
oocyte secreted protein 1
chr8_-_121825088 0.16 ENST00000520717.1
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr6_+_161123270 0.16 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
PLG
plasminogen
chr8_+_86851932 0.16 ENST00000517368.1
CTA-392E5.1
CTA-392E5.1
chr4_+_123653807 0.16 ENST00000314218.3
ENST00000542236.1
BBS12
Bardet-Biedl syndrome 12
chr10_+_103912137 0.15 ENST00000603742.1
ENST00000488254.2
ENST00000461421.1
ENST00000476468.1
ENST00000370007.5
NOLC1
nucleolar and coiled-body phosphoprotein 1
chr3_+_190105909 0.15 ENST00000456423.1
CLDN16
claudin 16
chr12_-_123187890 0.15 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr6_+_14117872 0.15 ENST00000379153.3
CD83
CD83 molecule
chr11_+_82904746 0.15 ENST00000393389.3
ENST00000528722.1
ANKRD42
ankyrin repeat domain 42
chr3_-_161090660 0.15 ENST00000359175.4
SPTSSB
serine palmitoyltransferase, small subunit B
chr2_+_185463093 0.15 ENST00000302277.6
ZNF804A
zinc finger protein 804A
chr1_+_41448820 0.15 ENST00000372616.1
CTPS1
CTP synthase 1
chr9_+_42704004 0.14 ENST00000457288.1
CBWD7
COBW domain containing 7
chrX_+_129535937 0.14 ENST00000305536.6
ENST00000370947.1
RBMX2
RNA binding motif protein, X-linked 2
chr15_-_89010607 0.14 ENST00000312475.4
MRPL46
mitochondrial ribosomal protein L46
chr6_+_135502408 0.14 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr11_-_47870091 0.14 ENST00000526870.1
NUP160
nucleoporin 160kDa
chr17_-_72588422 0.14 ENST00000375352.1
CD300LD
CD300 molecule-like family member d
chr12_-_56236690 0.14 ENST00000322569.4
MMP19
matrix metallopeptidase 19
chr17_-_34257731 0.13 ENST00000431884.2
ENST00000425909.3
ENST00000394528.3
ENST00000430160.2
RDM1
RAD52 motif 1
chr22_-_31324215 0.13 ENST00000429468.1
MORC2
MORC family CW-type zinc finger 2
chr17_-_73266616 0.13 ENST00000579194.1
ENST00000581777.1
MIF4GD
MIF4G domain containing
chrM_+_4431 0.13 ENST00000361453.3
MT-ND2
mitochondrially encoded NADH dehydrogenase 2
chr1_+_186649754 0.13 ENST00000608917.1
RP5-973M2.2
RP5-973M2.2
chr7_+_6713376 0.13 ENST00000399484.3
ENST00000544825.1
ENST00000401847.1
AC073343.1
Uncharacterized protein
chr7_-_76255444 0.12 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr1_+_100817262 0.12 ENST00000455467.1
CDC14A
cell division cycle 14A
chr1_+_207038699 0.12 ENST00000367098.1
IL20
interleukin 20
chr19_+_42301079 0.12 ENST00000596544.1
CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3
chr17_+_6918093 0.12 ENST00000439424.2
C17orf49
chromosome 17 open reading frame 49
chr5_-_176943917 0.12 ENST00000330503.7
DDX41
DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
chr4_-_144826682 0.12 ENST00000358615.4
ENST00000437468.2
GYPE
glycophorin E (MNS blood group)
chr8_+_31496809 0.12 ENST00000518104.1
ENST00000519301.1
NRG1
neuregulin 1
chr11_-_62609281 0.12 ENST00000525239.1
ENST00000538098.2
WDR74
WD repeat domain 74
chr8_-_66474884 0.11 ENST00000520902.1
CTD-3025N20.2
CTD-3025N20.2
chr7_-_144533074 0.11 ENST00000360057.3
ENST00000378099.3
TPK1
thiamin pyrophosphokinase 1
chr1_-_186649543 0.11 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr17_-_39216344 0.11 ENST00000391418.2
KRTAP2-3
keratin associated protein 2-3
chr19_-_51538148 0.11 ENST00000319590.4
ENST00000250351.4
KLK12
kallikrein-related peptidase 12
chr12_-_56236734 0.11 ENST00000548629.1
MMP19
matrix metallopeptidase 19
chr14_-_75083313 0.11 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2
CTD-2207P18.2
chr17_-_1508379 0.11 ENST00000412517.3
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr2_+_90248739 0.11 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chr19_+_18794470 0.11 ENST00000321949.8
ENST00000338797.6
CRTC1
CREB regulated transcription coactivator 1
chr11_-_58343319 0.11 ENST00000395074.2
LPXN
leupaxin
chr14_-_91710852 0.10 ENST00000535815.1
ENST00000529102.1
GPR68
G protein-coupled receptor 68
chr7_+_149535455 0.10 ENST00000223210.4
ENST00000460379.1
ZNF862
zinc finger protein 862
chr5_+_69321074 0.10 ENST00000380751.5
ENST00000380750.3
ENST00000503931.1
ENST00000506542.1
SERF1B
small EDRK-rich factor 1B (centromeric)
chr19_-_52254050 0.10 ENST00000600815.1
FPR1
formyl peptide receptor 1
chr20_+_4152356 0.10 ENST00000379460.2
SMOX
spermine oxidase
chr16_-_31519691 0.10 ENST00000567994.1
ENST00000430477.2
ENST00000570164.1
ENST00000327237.2
C16orf58
chromosome 16 open reading frame 58
chr17_-_73781567 0.10 ENST00000586607.1
H3F3B
H3 histone, family 3B (H3.3B)
chr22_+_38082330 0.10 ENST00000359114.4
NOL12
nucleolar protein 12
chr17_+_9745786 0.09 ENST00000304773.5
GLP2R
glucagon-like peptide 2 receptor
chr17_+_7461849 0.09 ENST00000338784.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr11_-_74022658 0.09 ENST00000427714.2
ENST00000331597.4
P4HA3
prolyl 4-hydroxylase, alpha polypeptide III
chr4_+_123747834 0.09 ENST00000264498.3
FGF2
fibroblast growth factor 2 (basic)
chr21_-_27462351 0.09 ENST00000448850.1
APP
amyloid beta (A4) precursor protein
chr1_-_71513471 0.09 ENST00000370931.3
ENST00000356595.4
ENST00000306666.5
ENST00000370932.2
ENST00000351052.5
ENST00000414819.1
ENST00000370924.4
PTGER3
prostaglandin E receptor 3 (subtype EP3)
chr19_+_40476912 0.09 ENST00000157812.2
PSMC4
proteasome (prosome, macropain) 26S subunit, ATPase, 4
chr14_+_66578299 0.09 ENST00000554187.1
ENST00000556662.1
ENST00000556291.1
ENST00000557723.1
ENST00000557050.1
RP11-783L4.1
RP11-783L4.1
chr19_-_6057282 0.09 ENST00000592281.1
RFX2
regulatory factor X, 2 (influences HLA class II expression)
chrY_-_20935572 0.09 ENST00000382852.1
ENST00000344884.4
ENST00000304790.3
HSFY2
heat shock transcription factor, Y linked 2
chr19_+_42300548 0.09 ENST00000344550.4
CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3
chr14_-_54425475 0.09 ENST00000559642.1
BMP4
bone morphogenetic protein 4
chr6_+_30844192 0.09 ENST00000502955.1
ENST00000505066.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr6_+_160542870 0.09 ENST00000324965.4
ENST00000457470.2
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr12_-_6960407 0.08 ENST00000540683.1
ENST00000229265.6
ENST00000535406.1
ENST00000422785.3
CDCA3
cell division cycle associated 3
chr19_-_51537982 0.08 ENST00000525263.1
KLK12
kallikrein-related peptidase 12
chr3_-_127842612 0.08 ENST00000417360.1
ENST00000322623.5
RUVBL1
RuvB-like AAA ATPase 1
chr12_+_53689309 0.08 ENST00000351500.3
ENST00000550846.1
ENST00000334478.4
ENST00000549759.1
PFDN5
prefoldin subunit 5
chr3_-_15540055 0.08 ENST00000605797.1
ENST00000435459.2
COLQ
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr8_+_27168988 0.08 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
PTK2B
protein tyrosine kinase 2 beta
chr7_+_95115210 0.08 ENST00000428113.1
ENST00000325885.5
ASB4
ankyrin repeat and SOCS box containing 4
chr11_+_117857063 0.08 ENST00000227752.3
ENST00000541785.1
ENST00000545409.1
IL10RA
interleukin 10 receptor, alpha
chr11_-_129062093 0.08 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr3_-_110612059 0.08 ENST00000485473.1
RP11-553A10.1
Uncharacterized protein
chr8_-_7220490 0.08 ENST00000400078.2
ZNF705G
zinc finger protein 705G
chr4_+_36283213 0.08 ENST00000357504.3
DTHD1
death domain containing 1
chr7_+_75677354 0.08 ENST00000461263.2
ENST00000315758.5
ENST00000443006.1
MDH2
malate dehydrogenase 2, NAD (mitochondrial)
chr12_+_57828521 0.08 ENST00000309668.2
INHBC
inhibin, beta C
chr12_-_56236711 0.08 ENST00000409200.3
MMP19
matrix metallopeptidase 19
chrY_+_20708557 0.08 ENST00000307393.2
ENST00000309834.4
ENST00000382856.2
HSFY1
heat shock transcription factor, Y-linked 1
chr13_+_76362974 0.08 ENST00000497947.2
LMO7
LIM domain 7
chr11_-_47870019 0.08 ENST00000378460.2
NUP160
nucleoporin 160kDa
chr1_-_119683251 0.08 ENST00000369426.5
ENST00000235521.4
WARS2
tryptophanyl tRNA synthetase 2, mitochondrial
chr3_-_107941209 0.08 ENST00000492106.1
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr15_-_60683326 0.08 ENST00000559350.1
ENST00000558986.1
ENST00000560389.1
ANXA2
annexin A2
chr4_-_23735183 0.08 ENST00000507666.1
RP11-380P13.2
RP11-380P13.2
chr19_-_37701386 0.08 ENST00000527838.1
ENST00000591492.1
ENST00000532828.2
ZNF585B
zinc finger protein 585B
chr17_+_38444115 0.08 ENST00000580824.1
ENST00000577249.1
CDC6
cell division cycle 6
chr11_-_18063973 0.07 ENST00000528338.1
TPH1
tryptophan hydroxylase 1
chr19_-_55791540 0.07 ENST00000433386.2
HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr1_-_25256368 0.07 ENST00000308873.6
RUNX3
runt-related transcription factor 3
chr4_+_71600144 0.07 ENST00000502653.1
RUFY3
RUN and FYVE domain containing 3
chr16_+_66413128 0.07 ENST00000563425.2
CDH5
cadherin 5, type 2 (vascular endothelium)
chr16_-_87350970 0.07 ENST00000567970.1
C16orf95
chromosome 16 open reading frame 95
chr19_+_9938562 0.07 ENST00000586895.1
ENST00000358666.3
ENST00000590068.1
ENST00000593087.1
UBL5
ubiquitin-like 5
chr17_-_8301132 0.07 ENST00000399398.2
RNF222
ring finger protein 222
chr19_-_44860820 0.07 ENST00000354340.4
ENST00000337401.4
ENST00000587909.1
ZNF112
zinc finger protein 112
chr9_-_92020841 0.07 ENST00000433650.1
SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr4_+_75230853 0.07 ENST00000244869.2
EREG
epiregulin
chr6_+_135502466 0.07 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr4_+_119809984 0.06 ENST00000307142.4
ENST00000448416.2
ENST00000429713.2
SYNPO2
synaptopodin 2
chr7_-_47520869 0.06 ENST00000415929.1
TNS3
tensin 3
chr19_+_41856816 0.06 ENST00000539627.1
TMEM91
transmembrane protein 91
chr15_+_45021183 0.06 ENST00000559390.1
TRIM69
tripartite motif containing 69
chr9_+_118950325 0.06 ENST00000534838.1
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr11_+_60609537 0.06 ENST00000227520.5
CCDC86
coiled-coil domain containing 86
chr17_-_67057047 0.06 ENST00000495634.1
ENST00000453985.2
ENST00000585714.1
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr6_+_135502501 0.06 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr12_-_129308487 0.06 ENST00000266771.5
SLC15A4
solute carrier family 15 (oligopeptide transporter), member 4
chr6_+_36853607 0.06 ENST00000480824.2
ENST00000355190.3
ENST00000373685.1
C6orf89
chromosome 6 open reading frame 89
chr13_-_103426112 0.06 ENST00000376032.4
ENST00000376029.3
TEX30
testis expressed 30
chr16_-_30773372 0.06 ENST00000545825.1
ENST00000541260.1
C16orf93
chromosome 16 open reading frame 93
chr1_-_8585945 0.06 ENST00000377464.1
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr11_+_9482512 0.06 ENST00000396602.2
ENST00000530463.1
ENST00000533542.1
ENST00000532577.1
ENST00000396597.3
ZNF143
zinc finger protein 143
chr3_-_112329110 0.06 ENST00000479368.1
CCDC80
coiled-coil domain containing 80
chr5_+_140027355 0.06 ENST00000417647.2
ENST00000507593.1
ENST00000508301.1
IK
IK cytokine, down-regulator of HLA II
chr5_-_133510456 0.06 ENST00000520417.1
SKP1
S-phase kinase-associated protein 1
chr13_-_25746416 0.05 ENST00000515384.1
ENST00000357816.2
AMER2
APC membrane recruitment protein 2
chr11_-_8816375 0.05 ENST00000530580.1
ST5
suppression of tumorigenicity 5
chr17_-_27278304 0.05 ENST00000577226.1
PHF12
PHD finger protein 12
chr10_+_24738355 0.05 ENST00000307544.6
KIAA1217
KIAA1217
chr2_-_132589601 0.05 ENST00000437330.1
AC103564.7
AC103564.7
chr1_+_180165672 0.05 ENST00000443059.1
QSOX1
quiescin Q6 sulfhydryl oxidase 1
chr9_+_27109392 0.05 ENST00000406359.4
TEK
TEK tyrosine kinase, endothelial
chr17_+_7461781 0.05 ENST00000349228.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chrX_-_153141302 0.05 ENST00000361699.4
ENST00000543994.1
ENST00000370057.3
ENST00000538883.1
ENST00000361981.3
L1CAM
L1 cell adhesion molecule
chr3_+_150264458 0.05 ENST00000487799.1
ENST00000460851.1
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr11_+_20044375 0.05 ENST00000525322.1
ENST00000530408.1
NAV2
neuron navigator 2
chr8_-_53322303 0.05 ENST00000276480.7
ST18
suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)
chr19_+_16296191 0.05 ENST00000589852.1
ENST00000263384.7
ENST00000588367.1
ENST00000587351.1
FAM32A
family with sequence similarity 32, member A
chr4_-_16077741 0.05 ENST00000447510.2
ENST00000540805.1
ENST00000539194.1
PROM1
prominin 1
chr12_+_122516626 0.05 ENST00000319080.7
MLXIP
MLX interacting protein
chr6_-_31628512 0.05 ENST00000375911.1
C6orf47
chromosome 6 open reading frame 47
chr18_-_29264467 0.05 ENST00000383131.3
ENST00000237019.7
B4GALT6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr20_-_5931109 0.05 ENST00000203001.2
TRMT6
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr5_+_140235469 0.05 ENST00000506939.2
ENST00000307360.5
PCDHA10
protocadherin alpha 10
chr17_-_33760269 0.05 ENST00000452764.3
SLFN12
schlafen family member 12
chr10_-_5638048 0.05 ENST00000478294.1
RP13-463N16.6
RP13-463N16.6
chr13_-_95131923 0.05 ENST00000377028.5
ENST00000446125.1
DCT
dopachrome tautomerase
chr8_-_53322347 0.05 ENST00000517580.1
ST18
suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)
chr12_-_10251603 0.04 ENST00000457018.2
CLEC1A
C-type lectin domain family 1, member A
chr19_+_29097595 0.04 ENST00000587961.1
AC079466.1
AC079466.1
chr4_-_10686475 0.04 ENST00000226951.6
CLNK
cytokine-dependent hematopoietic cell linker
chr3_-_8811288 0.04 ENST00000316793.3
ENST00000431493.1
OXTR
oxytocin receptor
chr19_-_51538118 0.04 ENST00000529888.1
KLK12
kallikrein-related peptidase 12
chr15_+_34638066 0.04 ENST00000333756.4
NUTM1
NUT midline carcinoma, family member 1
chr2_-_175712479 0.04 ENST00000443238.1
CHN1
chimerin 1

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.3 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.1 0.3 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.9 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 0.3 GO:0010193 response to ozone(GO:0010193)
0.1 0.2 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.2 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.1 0.3 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.4 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.1 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.0 0.2 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.1 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.1 GO:0042660 positive regulation of cell fate specification(GO:0042660)
0.0 0.3 GO:0001554 luteolysis(GO:0001554)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.4 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.1 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0052417 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.1 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.1 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 0.1 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.1 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.2 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.1 GO:2000007 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.1 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.1 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.1 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 1.0 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.4 GO:0042755 eating behavior(GO:0042755)
0.0 0.1 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.1 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.2 GO:0044849 estrous cycle(GO:0044849)
0.0 0.0 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.1 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693) semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.0 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.8 GO:0045773 positive regulation of axon extension(GO:0045773)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.8 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0044292 dendrite terminus(GO:0044292)
0.0 1.0 GO:0001533 cornified envelope(GO:0001533)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0097449 astrocyte projection(GO:0097449)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004145 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.1 0.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.2 GO:1904854 proteasome core complex binding(GO:1904854)
0.1 0.3 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.1 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.4 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0052894 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.0 0.1 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.3 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.3 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.1 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation