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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PAX6

Z-value: 0.52

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Transcription factors associated with PAX6

Gene Symbol Gene ID Gene Info
PAX6
ENSG00000007372.16 paired box 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX6hg19_v2_chr11_-_31839488_318395150.777.2e-02Click!

Activity profile of PAX6 motif

Sorted Z-values of PAX6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_89458287 0.47 ENST00000370485.2
CCBL2
cysteine conjugate-beta lyase 2
chr2_+_149402989 0.34 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr5_+_147691979 0.29 ENST00000274565.4
SPINK7
serine peptidase inhibitor, Kazal type 7 (putative)
chr21_+_39628780 0.28 ENST00000417042.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr16_-_47493041 0.26 ENST00000565940.2
ITFG1
integrin alpha FG-GAP repeat containing 1
chr7_+_112120908 0.24 ENST00000439068.2
ENST00000312849.4
ENST00000429049.1
LSMEM1
leucine-rich single-pass membrane protein 1
chr17_-_39216344 0.23 ENST00000391418.2
KRTAP2-3
keratin associated protein 2-3
chr8_-_95487272 0.23 ENST00000297592.5
RAD54B
RAD54 homolog B (S. cerevisiae)
chr6_-_52859046 0.22 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
GSTA4
glutathione S-transferase alpha 4
chr17_-_58499766 0.21 ENST00000588898.1
USP32
ubiquitin specific peptidase 32
chr12_+_27175476 0.20 ENST00000546323.1
ENST00000282892.3
MED21
mediator complex subunit 21
chr14_+_57671888 0.18 ENST00000391612.1
AL391152.1
AL391152.1
chr11_+_1295809 0.17 ENST00000598274.1
AC136297.1
Uncharacterized protein
chr1_+_26759295 0.17 ENST00000430232.1
DHDDS
dehydrodolichyl diphosphate synthase
chr15_-_65282274 0.17 ENST00000204566.2
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr1_-_89458415 0.16 ENST00000321792.5
ENST00000370491.3
RBMXL1
CCBL2
RNA binding motif protein, X-linked-like 1
cysteine conjugate-beta lyase 2
chr2_+_172778952 0.16 ENST00000392584.1
ENST00000264108.4
HAT1
histone acetyltransferase 1
chr6_+_26225354 0.16 ENST00000360408.1
HIST1H3E
histone cluster 1, H3e
chr12_-_3982548 0.16 ENST00000397096.2
ENST00000447133.3
ENST00000450737.2
PARP11
poly (ADP-ribose) polymerase family, member 11
chr6_-_26033796 0.15 ENST00000259791.2
HIST1H2AB
histone cluster 1, H2ab
chr2_+_109204909 0.15 ENST00000393310.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr8_-_18711866 0.15 ENST00000519851.1
PSD3
pleckstrin and Sec7 domain containing 3
chr10_-_27389320 0.15 ENST00000436985.2
ANKRD26
ankyrin repeat domain 26
chr6_+_26156551 0.15 ENST00000304218.3
HIST1H1E
histone cluster 1, H1e
chr14_+_61995722 0.15 ENST00000556347.1
RP11-47I22.4
RP11-47I22.4
chr13_+_96085847 0.14 ENST00000376873.3
CLDN10
claudin 10
chr16_-_18911366 0.14 ENST00000565224.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr11_-_28129656 0.14 ENST00000263181.6
KIF18A
kinesin family member 18A
chr8_-_121457332 0.14 ENST00000518918.1
MRPL13
mitochondrial ribosomal protein L13
chr12_+_113416340 0.14 ENST00000552756.1
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr18_+_61420169 0.13 ENST00000425392.1
ENST00000336429.2
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr12_-_3982511 0.12 ENST00000427057.2
ENST00000228820.4
PARP11
poly (ADP-ribose) polymerase family, member 11
chr22_-_30642728 0.12 ENST00000403987.3
LIF
leukemia inhibitory factor
chr5_+_118668846 0.11 ENST00000513374.1
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr1_+_207925391 0.11 ENST00000358170.2
ENST00000354848.1
ENST00000322918.5
ENST00000367042.1
ENST00000367041.1
ENST00000357714.1
ENST00000322875.4
ENST00000367047.1
ENST00000441839.2
ENST00000361067.1
ENST00000360212.2
ENST00000480003.1
CD46
CD46 molecule, complement regulatory protein
chr17_+_57297807 0.11 ENST00000284116.4
ENST00000581140.1
ENST00000581276.1
GDPD1
glycerophosphodiester phosphodiesterase domain containing 1
chr4_+_130017268 0.11 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
C4orf33
chromosome 4 open reading frame 33
chr14_+_32547434 0.11 ENST00000556191.1
ENST00000554090.1
ARHGAP5
Rho GTPase activating protein 5
chr18_+_61445007 0.11 ENST00000447428.1
ENST00000546027.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr1_-_87379785 0.11 ENST00000401030.3
ENST00000370554.1
SEP15
Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.
chr18_-_21242729 0.11 ENST00000585908.2
ANKRD29
ankyrin repeat domain 29
chr4_-_88141615 0.11 ENST00000545252.1
ENST00000425278.2
ENST00000498875.2
KLHL8
kelch-like family member 8
chr16_+_84801852 0.11 ENST00000569925.1
ENST00000567526.1
USP10
ubiquitin specific peptidase 10
chr3_-_196910721 0.11 ENST00000443183.1
DLG1
discs, large homolog 1 (Drosophila)
chr2_-_86116093 0.11 ENST00000377332.3
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr5_-_114938090 0.11 ENST00000427199.2
TICAM2
toll-like receptor adaptor molecule 2
chr1_+_203765437 0.10 ENST00000550078.1
ZBED6
zinc finger, BED-type containing 6
chr12_+_69080734 0.10 ENST00000378905.2
NUP107
nucleoporin 107kDa
chr8_+_121457642 0.10 ENST00000305949.1
MTBP
Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa
chr12_+_83080659 0.10 ENST00000321196.3
TMTC2
transmembrane and tetratricopeptide repeat containing 2
chr18_+_61445205 0.09 ENST00000431370.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr4_+_70916119 0.09 ENST00000246896.3
ENST00000511674.1
HTN1
histatin 1
chr18_+_32173276 0.09 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA
dystrobrevin, alpha
chr2_-_176867534 0.09 ENST00000445472.1
KIAA1715
KIAA1715
chr3_-_196910477 0.09 ENST00000447466.1
DLG1
discs, large homolog 1 (Drosophila)
chr15_-_78358465 0.09 ENST00000435468.1
TBC1D2B
TBC1 domain family, member 2B
chr3_+_151531810 0.09 ENST00000232892.7
AADAC
arylacetamide deacetylase
chr1_+_104068562 0.09 ENST00000423855.2
RNPC3
RNA-binding region (RNP1, RRM) containing 3
chr21_-_18985230 0.09 ENST00000457956.1
ENST00000348354.6
BTG3
BTG family, member 3
chr4_-_68749745 0.09 ENST00000283916.6
TMPRSS11D
transmembrane protease, serine 11D
chr3_+_167582561 0.09 ENST00000463642.1
ENST00000464514.1
RP11-298O21.6
RP11-298O21.7
RP11-298O21.6
RP11-298O21.7
chr6_-_42162654 0.09 ENST00000230361.3
GUCA1B
guanylate cyclase activator 1B (retina)
chr3_-_101232019 0.08 ENST00000394095.2
ENST00000394091.1
ENST00000394094.2
ENST00000358203.3
ENST00000348610.3
ENST00000314261.7
SENP7
SUMO1/sentrin specific peptidase 7
chr1_+_161677034 0.08 ENST00000349527.4
ENST00000309691.6
ENST00000294796.4
ENST00000367953.3
ENST00000367950.1
FCRLA
Fc receptor-like A
chr1_+_79115503 0.08 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr8_+_59323823 0.08 ENST00000399598.2
UBXN2B
UBX domain protein 2B
chr14_-_36645674 0.08 ENST00000556013.2
PTCSC3
papillary thyroid carcinoma susceptibility candidate 3 (non-protein coding)
chr22_-_29949657 0.08 ENST00000428374.1
THOC5
THO complex 5
chr4_-_68749699 0.08 ENST00000545541.1
TMPRSS11D
transmembrane protease, serine 11D
chr10_-_118764862 0.08 ENST00000260777.10
KIAA1598
KIAA1598
chr17_-_76824975 0.08 ENST00000586066.2
USP36
ubiquitin specific peptidase 36
chr16_-_79804435 0.08 ENST00000562921.1
ENST00000566729.1
RP11-345M22.2
RP11-345M22.2
chr11_+_14926543 0.08 ENST00000523376.1
CALCB
calcitonin-related polypeptide beta
chr15_-_85201779 0.08 ENST00000360476.3
ENST00000394588.3
NMB
neuromedin B
chr7_+_138943265 0.08 ENST00000483726.1
UBN2
ubinuclein 2
chr5_-_159546396 0.08 ENST00000523662.1
ENST00000456329.3
ENST00000307063.7
PWWP2A
PWWP domain containing 2A
chr1_+_26758790 0.07 ENST00000427245.2
ENST00000525682.2
ENST00000236342.7
ENST00000526219.1
ENST00000374185.3
ENST00000360009.2
DHDDS
dehydrodolichyl diphosphate synthase
chr12_+_111284764 0.07 ENST00000545036.1
ENST00000308208.5
CCDC63
coiled-coil domain containing 63
chr19_+_35820064 0.07 ENST00000341773.6
ENST00000600131.1
ENST00000270311.6
ENST00000595780.1
ENST00000597916.1
ENST00000593867.1
ENST00000600424.1
ENST00000599811.1
ENST00000536635.2
ENST00000085219.5
ENST00000544992.2
ENST00000419549.2
CD22
CD22 molecule
chr5_+_67485704 0.07 ENST00000520762.1
RP11-404L6.2
Uncharacterized protein
chr8_-_121457608 0.07 ENST00000306185.3
MRPL13
mitochondrial ribosomal protein L13
chr7_+_65552756 0.07 ENST00000450043.1
AC068533.7
AC068533.7
chr11_-_117747327 0.07 ENST00000584230.1
ENST00000527429.1
ENST00000584394.1
ENST00000532984.1
FXYD6
FXYD6-FXYD2
FXYD domain containing ion transport regulator 6
FXYD6-FXYD2 readthrough
chr8_-_66474884 0.07 ENST00000520902.1
CTD-3025N20.2
CTD-3025N20.2
chr4_+_76995855 0.07 ENST00000355810.4
ENST00000349321.3
ART3
ADP-ribosyltransferase 3
chr4_-_88141755 0.07 ENST00000273963.5
KLHL8
kelch-like family member 8
chr8_-_19615382 0.07 ENST00000544602.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr10_-_75226166 0.07 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr4_-_65275162 0.07 ENST00000381210.3
ENST00000507440.1
TECRL
trans-2,3-enoyl-CoA reductase-like
chr11_-_57298187 0.07 ENST00000525158.1
ENST00000257245.4
ENST00000525587.1
TIMM10
translocase of inner mitochondrial membrane 10 homolog (yeast)
chr22_-_17702729 0.07 ENST00000449907.2
ENST00000441548.1
ENST00000399839.1
CECR1
cat eye syndrome chromosome region, candidate 1
chr1_+_218683438 0.07 ENST00000443836.1
C1orf143
chromosome 1 open reading frame 143
chr12_+_59194154 0.07 ENST00000548969.1
RP11-362K2.2
Protein LOC100506869
chr7_+_90338547 0.07 ENST00000446790.1
CDK14
cyclin-dependent kinase 14
chr5_+_93954039 0.07 ENST00000265140.5
ANKRD32
ankyrin repeat domain 32
chr7_-_84121858 0.07 ENST00000448879.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr15_-_23034322 0.07 ENST00000539711.2
ENST00000560039.1
ENST00000398013.3
ENST00000337451.3
ENST00000359727.4
ENST00000398014.2
NIPA2
non imprinted in Prader-Willi/Angelman syndrome 2
chr11_-_61849656 0.07 ENST00000524942.1
RP11-810P12.5
RP11-810P12.5
chr14_+_56127960 0.06 ENST00000553624.1
KTN1
kinectin 1 (kinesin receptor)
chr20_+_48807351 0.06 ENST00000303004.3
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr12_-_85306562 0.06 ENST00000551612.1
ENST00000450363.3
ENST00000552192.1
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr2_-_176867501 0.06 ENST00000535310.1
KIAA1715
KIAA1715
chr2_-_29093132 0.06 ENST00000306108.5
TRMT61B
tRNA methyltransferase 61 homolog B (S. cerevisiae)
chr3_-_18486354 0.06 ENST00000493952.2
ENST00000440737.1
SATB1
SATB homeobox 1
chr19_+_35939154 0.06 ENST00000599180.2
FFAR2
free fatty acid receptor 2
chr12_-_56352368 0.06 ENST00000549404.1
PMEL
premelanosome protein
chr5_+_140602904 0.06 ENST00000515856.2
ENST00000239449.4
PCDHB14
protocadherin beta 14
chr8_-_79470728 0.06 ENST00000522807.1
ENST00000519242.1
ENST00000522302.1
RP11-594N15.2
RP11-594N15.2
chr1_-_110933611 0.06 ENST00000472422.2
ENST00000437429.2
SLC16A4
solute carrier family 16, member 4
chr3_-_142297668 0.06 ENST00000350721.4
ENST00000383101.3
ATR
ataxia telangiectasia and Rad3 related
chr20_-_32308028 0.06 ENST00000409299.3
ENST00000217398.3
ENST00000344022.3
PXMP4
peroxisomal membrane protein 4, 24kDa
chr12_+_111284805 0.06 ENST00000552694.1
CCDC63
coiled-coil domain containing 63
chr1_-_43282945 0.06 ENST00000537227.1
CCDC23
coiled-coil domain containing 23
chr7_-_152373216 0.06 ENST00000359321.1
XRCC2
X-ray repair complementing defective repair in Chinese hamster cells 2
chr10_-_16563870 0.06 ENST00000298943.3
C1QL3
complement component 1, q subcomponent-like 3
chr14_+_66578299 0.05 ENST00000554187.1
ENST00000556662.1
ENST00000556291.1
ENST00000557723.1
ENST00000557050.1
RP11-783L4.1
RP11-783L4.1
chr9_-_116861337 0.05 ENST00000374118.3
KIF12
kinesin family member 12
chr1_+_114522049 0.05 ENST00000369551.1
ENST00000320334.4
OLFML3
olfactomedin-like 3
chr10_-_27389392 0.05 ENST00000376087.4
ANKRD26
ankyrin repeat domain 26
chr6_-_31846744 0.05 ENST00000414427.1
ENST00000229729.6
ENST00000375562.4
SLC44A4
solute carrier family 44, member 4
chr8_-_54934708 0.05 ENST00000520534.1
ENST00000518784.1
ENST00000522635.1
TCEA1
transcription elongation factor A (SII), 1
chr7_+_102292796 0.05 ENST00000436228.2
SPDYE2B
speedy/RINGO cell cycle regulator family member E2B
chr1_-_156722015 0.05 ENST00000368209.5
HDGF
hepatoma-derived growth factor
chr3_-_111852128 0.05 ENST00000308910.4
GCSAM
germinal center-associated, signaling and motility
chr2_-_136743169 0.05 ENST00000264161.4
DARS
aspartyl-tRNA synthetase
chr2_-_162931052 0.05 ENST00000360534.3
DPP4
dipeptidyl-peptidase 4
chr16_-_18937726 0.05 ENST00000389467.3
ENST00000446231.2
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr7_+_90338712 0.05 ENST00000265741.3
ENST00000406263.1
CDK14
cyclin-dependent kinase 14
chr1_-_43282906 0.05 ENST00000372521.4
CCDC23
coiled-coil domain containing 23
chr2_+_192110199 0.05 ENST00000304164.4
MYO1B
myosin IB
chr13_+_25875662 0.05 ENST00000381736.3
ENST00000463407.1
ENST00000381718.3
NUPL1
nucleoporin like 1
chr7_-_97501733 0.05 ENST00000444334.1
ENST00000422745.1
ENST00000394308.3
ENST00000451771.1
ENST00000175506.4
ASNS
asparagine synthetase (glutamine-hydrolyzing)
chr1_+_87380299 0.05 ENST00000370551.4
ENST00000370550.5
HS2ST1
heparan sulfate 2-O-sulfotransferase 1
chr12_+_58937907 0.05 ENST00000546977.1
RP11-362K2.2
Protein LOC100506869
chr18_+_18822185 0.05 ENST00000424526.1
ENST00000400483.4
ENST00000431264.1
GREB1L
growth regulation by estrogen in breast cancer-like
chrX_-_6146876 0.05 ENST00000381095.3
NLGN4X
neuroligin 4, X-linked
chr6_+_88299833 0.04 ENST00000392844.3
ENST00000257789.4
ENST00000546266.1
ENST00000417380.2
ORC3
origin recognition complex, subunit 3
chr13_-_24007815 0.04 ENST00000382298.3
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chrX_-_13835147 0.04 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr10_-_13523073 0.04 ENST00000440282.1
BEND7
BEN domain containing 7
chr11_+_128563652 0.04 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr7_+_133615169 0.04 ENST00000541309.1
EXOC4
exocyst complex component 4
chr4_+_187148556 0.04 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr21_-_16135411 0.04 ENST00000435315.2
AF127936.5
AF127936.5
chr12_+_83080724 0.04 ENST00000548305.1
TMTC2
transmembrane and tetratricopeptide repeat containing 2
chrX_-_53461288 0.04 ENST00000375298.4
ENST00000375304.5
HSD17B10
hydroxysteroid (17-beta) dehydrogenase 10
chr4_-_174320687 0.04 ENST00000296506.3
SCRG1
stimulator of chondrogenesis 1
chr19_-_10047219 0.04 ENST00000264833.4
OLFM2
olfactomedin 2
chr1_-_87380002 0.04 ENST00000331835.5
SEP15
Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.
chr5_-_98262240 0.04 ENST00000284049.3
CHD1
chromodomain helicase DNA binding protein 1
chr6_-_134373732 0.04 ENST00000275230.5
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr11_-_11374904 0.04 ENST00000528848.2
CSNK2A3
casein kinase 2, alpha 3 polypeptide
chr8_+_22428457 0.04 ENST00000517962.1
SORBS3
sorbin and SH3 domain containing 3
chr11_-_117747607 0.04 ENST00000540359.1
ENST00000539526.1
FXYD6
FXYD domain containing ion transport regulator 6
chr3_+_172034218 0.04 ENST00000366261.2
AC092964.1
Uncharacterized protein
chr1_-_204183071 0.04 ENST00000308302.3
GOLT1A
golgi transport 1A
chr9_+_129097520 0.04 ENST00000436593.3
MVB12B
multivesicular body subunit 12B
chr12_+_78224667 0.04 ENST00000549464.1
NAV3
neuron navigator 3
chr2_+_179184955 0.04 ENST00000315022.2
OSBPL6
oxysterol binding protein-like 6
chr4_+_129349188 0.04 ENST00000511497.1
RP11-420A23.1
RP11-420A23.1
chr3_-_171489085 0.04 ENST00000418087.1
PLD1
phospholipase D1, phosphatidylcholine-specific
chr16_+_31128978 0.04 ENST00000448516.2
ENST00000219797.4
KAT8
K(lysine) acetyltransferase 8
chr2_-_70520539 0.04 ENST00000482975.2
ENST00000438261.1
SNRPG
small nuclear ribonucleoprotein polypeptide G
chr1_+_167298281 0.03 ENST00000367862.5
POU2F1
POU class 2 homeobox 1
chr6_-_64029879 0.03 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
LGSN
lengsin, lens protein with glutamine synthetase domain
chr2_+_238877424 0.03 ENST00000434655.1
UBE2F
ubiquitin-conjugating enzyme E2F (putative)
chr1_-_229644034 0.03 ENST00000366678.3
ENST00000261396.3
ENST00000537506.1
NUP133
nucleoporin 133kDa
chr2_+_192109911 0.03 ENST00000418908.1
ENST00000339514.4
ENST00000392318.3
MYO1B
myosin IB
chr18_-_37380230 0.03 ENST00000591629.1
LINC00669
long intergenic non-protein coding RNA 669
chr1_-_110933663 0.03 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4
solute carrier family 16, member 4
chr21_+_39628655 0.03 ENST00000398925.1
ENST00000398928.1
ENST00000328656.4
ENST00000443341.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr10_+_35894338 0.03 ENST00000321660.1
GJD4
gap junction protein, delta 4, 40.1kDa
chr4_+_87928140 0.03 ENST00000307808.6
AFF1
AF4/FMR2 family, member 1
chr12_+_6949964 0.03 ENST00000541978.1
ENST00000435982.2
GNB3
guanine nucleotide binding protein (G protein), beta polypeptide 3
chr9_+_93589734 0.03 ENST00000375746.1
SYK
spleen tyrosine kinase
chr2_+_191334212 0.03 ENST00000444317.1
ENST00000535751.1
MFSD6
major facilitator superfamily domain containing 6
chr20_+_32250079 0.03 ENST00000375222.3
C20orf144
chromosome 20 open reading frame 144
chrX_-_106449656 0.03 ENST00000372466.4
ENST00000421752.1
ENST00000372461.3
NUP62CL
nucleoporin 62kDa C-terminal like
chr9_-_13279563 0.03 ENST00000541718.1
MPDZ
multiple PDZ domain protein
chr19_+_51628165 0.03 ENST00000250360.3
ENST00000440804.3
SIGLEC9
sialic acid binding Ig-like lectin 9
chr20_-_62178857 0.03 ENST00000217188.1
SRMS
src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
chr1_-_86174065 0.03 ENST00000370574.3
ENST00000431532.2
ZNHIT6
zinc finger, HIT-type containing 6
chr7_-_97501706 0.03 ENST00000455086.1
ENST00000453600.1
ASNS
asparagine synthetase (glutamine-hydrolyzing)
chrX_+_37545012 0.03 ENST00000378616.3
XK
X-linked Kx blood group (McLeod syndrome)
chr11_+_28129795 0.03 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
METTL15
methyltransferase like 15
chr2_-_85625857 0.03 ENST00000453973.1
CAPG
capping protein (actin filament), gelsolin-like
chr1_+_26758849 0.03 ENST00000533087.1
ENST00000531312.1
ENST00000525165.1
ENST00000525326.1
ENST00000525546.1
ENST00000436153.2
ENST00000530781.1
DHDDS
dehydrodolichyl diphosphate synthase
chr11_+_65554493 0.03 ENST00000335987.3
OVOL1
ovo-like zinc finger 1
chr6_-_41039567 0.03 ENST00000468811.1
OARD1
O-acyl-ADP-ribose deacylase 1
chr15_+_52043758 0.03 ENST00000249700.4
ENST00000539962.2
TMOD2
tropomodulin 2 (neuronal)
chr6_+_42896865 0.03 ENST00000372836.4
ENST00000394142.3
CNPY3
canopy FGF signaling regulator 3
chrX_-_138914394 0.02 ENST00000327569.3
ENST00000361648.2
ENST00000370543.1
ENST00000359686.2
ATP11C
ATPase, class VI, type 11C
chr19_-_36019123 0.02 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
SBSN
suprabasin
chr2_+_228190066 0.02 ENST00000436237.1
ENST00000443428.2
ENST00000418961.1
MFF
mitochondrial fission factor
chr1_+_203651937 0.02 ENST00000341360.2
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr3_-_111852061 0.02 ENST00000488580.1
ENST00000460387.2
ENST00000484193.1
ENST00000487901.1
GCSAM
germinal center-associated, signaling and motility
chr4_+_139694701 0.02 ENST00000502606.1
RP11-98O2.1
RP11-98O2.1
chr11_+_134094508 0.02 ENST00000281187.5
ENST00000525095.2
VPS26B
vacuolar protein sorting 26 homolog B (S. pombe)
chr15_+_52155001 0.02 ENST00000544199.1
TMOD3
tropomodulin 3 (ubiquitous)
chr12_-_47473425 0.02 ENST00000550413.1
AMIGO2
adhesion molecule with Ig-like domain 2

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 0.3 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.3 GO:1902572 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.1 GO:0035668 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0002877 acute inflammatory response to non-antigenic stimulus(GO:0002525) regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.2 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.1 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.1 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.0 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.0 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.0 0.1 GO:0048880 sensory system development(GO:0048880)
0.0 0.1 GO:0070981 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0018377 protein myristoylation(GO:0018377)
0.0 0.1 GO:1904884 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 0.1 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.1 GO:0036343 psychomotor behavior(GO:0036343)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.0 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.1 GO:0000788 nuclear nucleosome(GO:0000788)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.1 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.1 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705)
0.0 0.1 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism