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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for OTX2_CRX

Z-value: 0.50

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Transcription factors associated with OTX2_CRX

Gene Symbol Gene ID Gene Info
OTX2
ENSG00000165588.12 orthodenticle homeobox 2
CRX
ENSG00000105392.11 cone-rod homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CRXhg19_v2_chr19_+_48325097_483252110.236.7e-01Click!

Activity profile of OTX2_CRX motif

Sorted Z-values of OTX2_CRX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_44092784 0.45 ENST00000458412.1
HYPK
huntingtin interacting protein K
chrX_+_69488174 0.31 ENST00000480877.2
ENST00000307959.8
ARR3
arrestin 3, retinal (X-arrestin)
chr7_-_100171270 0.27 ENST00000538735.1
SAP25
Sin3A-associated protein, 25kDa
chr17_+_74536164 0.25 ENST00000586148.1
PRCD
progressive rod-cone degeneration
chr17_-_38859996 0.25 ENST00000264651.2
KRT24
keratin 24
chr17_-_40264692 0.24 ENST00000591220.1
ENST00000251642.3
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chrX_+_69488155 0.22 ENST00000374495.3
ARR3
arrestin 3, retinal (X-arrestin)
chr16_-_31076332 0.20 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
ZNF668
zinc finger protein 668
chr15_-_74494779 0.19 ENST00000571341.1
STRA6
stimulated by retinoic acid 6
chr5_+_133451254 0.18 ENST00000517851.1
ENST00000521639.1
ENST00000522375.1
ENST00000378560.4
ENST00000432532.2
ENST00000520958.1
ENST00000518915.1
ENST00000395023.1
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr7_-_128415844 0.17 ENST00000249389.2
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr19_-_51538148 0.17 ENST00000319590.4
ENST00000250351.4
KLK12
kallikrein-related peptidase 12
chrX_+_15767971 0.17 ENST00000479740.1
ENST00000454127.2
CA5B
carbonic anhydrase VB, mitochondrial
chr5_+_5140436 0.16 ENST00000511368.1
ENST00000274181.7
ADAMTS16
ADAM metallopeptidase with thrombospondin type 1 motif, 16
chr11_-_36619771 0.16 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
RAG2
recombination activating gene 2
chr8_-_25281747 0.16 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr12_+_85673868 0.15 ENST00000316824.3
ALX1
ALX homeobox 1
chr18_+_32290218 0.15 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
DTNA
dystrobrevin, alpha
chr7_-_17500294 0.13 ENST00000439046.1
AC019117.2
AC019117.2
chrX_+_153769446 0.13 ENST00000422680.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr19_-_51538118 0.13 ENST00000529888.1
KLK12
kallikrein-related peptidase 12
chr6_+_148593425 0.12 ENST00000367469.1
SASH1
SAM and SH3 domain containing 1
chr14_-_22005197 0.12 ENST00000541965.1
SALL2
spalt-like transcription factor 2
chr9_-_98268883 0.11 ENST00000551630.1
ENST00000548420.1
PTCH1
patched 1
chr1_-_165414414 0.11 ENST00000359842.5
RXRG
retinoid X receptor, gamma
chr6_-_33297013 0.11 ENST00000453407.1
DAXX
death-domain associated protein
chr19_-_55866104 0.11 ENST00000326529.4
COX6B2
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chrX_-_15619076 0.11 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr7_-_97881429 0.10 ENST00000420697.1
ENST00000379795.3
ENST00000415086.1
ENST00000542604.1
ENST00000447648.2
TECPR1
tectonin beta-propeller repeat containing 1
chr6_+_35310312 0.10 ENST00000448077.2
ENST00000360694.3
ENST00000418635.2
ENST00000444397.1
PPARD
peroxisome proliferator-activated receptor delta
chr3_+_49058444 0.09 ENST00000326925.6
ENST00000395458.2
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr16_-_31076273 0.09 ENST00000426488.2
ZNF668
zinc finger protein 668
chr1_+_200863949 0.09 ENST00000413687.2
C1orf106
chromosome 1 open reading frame 106
chr17_-_39661947 0.09 ENST00000590425.1
KRT13
keratin 13
chr5_-_88179302 0.09 ENST00000504921.2
MEF2C
myocyte enhancer factor 2C
chr10_+_103986085 0.08 ENST00000370005.3
ELOVL3
ELOVL fatty acid elongase 3
chr17_-_4643161 0.08 ENST00000574412.1
CXCL16
chemokine (C-X-C motif) ligand 16
chr17_-_43210580 0.08 ENST00000538093.1
ENST00000590644.1
PLCD3
phospholipase C, delta 3
chr6_+_35310391 0.08 ENST00000337400.2
ENST00000311565.4
ENST00000540939.1
PPARD
peroxisome proliferator-activated receptor delta
chr15_-_74495188 0.08 ENST00000563965.1
ENST00000395105.4
STRA6
stimulated by retinoic acid 6
chr19_-_55866061 0.07 ENST00000588572.2
ENST00000593184.1
ENST00000589467.1
COX6B2
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr1_-_26633480 0.07 ENST00000450041.1
UBXN11
UBX domain protein 11
chr3_+_49057876 0.07 ENST00000326912.4
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr11_+_72975524 0.07 ENST00000540342.1
ENST00000542092.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr2_-_14541060 0.07 ENST00000418420.1
ENST00000417751.1
LINC00276
long intergenic non-protein coding RNA 276
chr1_-_117664317 0.07 ENST00000256649.4
ENST00000369464.3
ENST00000485032.1
TRIM45
tripartite motif containing 45
chr4_+_124571409 0.07 ENST00000514823.1
ENST00000511919.1
ENST00000508111.1
RP11-93L9.1
long intergenic non-protein coding RNA 1091
chr2_+_183943464 0.06 ENST00000354221.4
DUSP19
dual specificity phosphatase 19
chr5_-_41794313 0.06 ENST00000512084.1
OXCT1
3-oxoacid CoA transferase 1
chr3_-_49058479 0.06 ENST00000440857.1
DALRD3
DALR anticodon binding domain containing 3
chr11_+_72975559 0.06 ENST00000349767.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr17_-_39661849 0.06 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
KRT13
keratin 13
chr16_+_58010339 0.06 ENST00000290871.5
ENST00000441824.2
TEPP
testis, prostate and placenta expressed
chr5_-_149324306 0.06 ENST00000255266.5
PDE6A
phosphodiesterase 6A, cGMP-specific, rod, alpha
chr10_-_94003003 0.06 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chrX_-_124097620 0.06 ENST00000371130.3
ENST00000422452.2
TENM1
teneurin transmembrane protein 1
chr19_+_48325097 0.05 ENST00000221996.7
ENST00000539067.1
CRX
cone-rod homeobox
chr18_-_70532906 0.05 ENST00000299430.2
ENST00000397929.1
NETO1
neuropilin (NRP) and tolloid (TLL)-like 1
chr5_+_50679506 0.05 ENST00000511384.1
ISL1
ISL LIM homeobox 1
chr6_+_130339710 0.05 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr2_-_175711133 0.05 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chr19_-_51537982 0.05 ENST00000525263.1
KLK12
kallikrein-related peptidase 12
chrX_-_153363125 0.05 ENST00000407218.1
ENST00000453960.2
MECP2
methyl CpG binding protein 2 (Rett syndrome)
chr5_-_88179017 0.05 ENST00000514028.1
ENST00000514015.1
ENST00000503075.1
ENST00000437473.2
MEF2C
myocyte enhancer factor 2C
chr20_-_18774614 0.05 ENST00000412553.1
LINC00652
long intergenic non-protein coding RNA 652
chr3_+_49059038 0.05 ENST00000451378.2
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr11_+_101983176 0.05 ENST00000524575.1
YAP1
Yes-associated protein 1
chrX_+_153769409 0.05 ENST00000440286.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr14_+_96722152 0.05 ENST00000216629.6
BDKRB1
bradykinin receptor B1
chr16_-_58004992 0.05 ENST00000564448.1
ENST00000251102.8
ENST00000311183.4
CNGB1
cyclic nucleotide gated channel beta 1
chr9_-_127358087 0.05 ENST00000475178.1
NR6A1
nuclear receptor subfamily 6, group A, member 1
chr1_+_164528437 0.04 ENST00000485769.1
PBX1
pre-B-cell leukemia homeobox 1
chr19_-_42931567 0.04 ENST00000244289.4
LIPE
lipase, hormone-sensitive
chr11_+_72975578 0.04 ENST00000393592.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr17_-_4689727 0.04 ENST00000328739.5
ENST00000354194.4
VMO1
vitelline membrane outer layer 1 homolog (chicken)
chr17_+_16945820 0.04 ENST00000577514.1
MPRIP
myosin phosphatase Rho interacting protein
chrX_-_49089771 0.04 ENST00000376251.1
ENST00000323022.5
ENST00000376265.2
CACNA1F
calcium channel, voltage-dependent, L type, alpha 1F subunit
chr18_-_64271363 0.04 ENST00000262150.2
CDH19
cadherin 19, type 2
chr14_-_71107921 0.04 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
CTD-2540L5.5
CTD-2540L5.6
chr9_-_131486367 0.04 ENST00000372663.4
ENST00000406904.2
ENST00000452105.1
ENST00000372672.2
ENST00000372667.5
ZDHHC12
zinc finger, DHHC-type containing 12
chr5_-_524445 0.04 ENST00000514375.1
ENST00000264938.3
SLC9A3
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
chr1_+_180875711 0.04 ENST00000434447.1
RP11-46A10.2
RP11-46A10.2
chr7_-_128171123 0.03 ENST00000608477.1
RP11-212P7.2
RP11-212P7.2
chr20_-_31124186 0.03 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr13_-_49975632 0.03 ENST00000457041.1
ENST00000355854.4
CAB39L
calcium binding protein 39-like
chr17_+_43318434 0.03 ENST00000587489.1
FMNL1
formin-like 1
chr14_-_101034407 0.03 ENST00000443071.2
ENST00000557378.1
BEGAIN
brain-enriched guanylate kinase-associated
chr7_-_78400598 0.03 ENST00000536571.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr5_-_88120083 0.03 ENST00000509373.1
MEF2C
myocyte enhancer factor 2C
chr3_+_50649302 0.03 ENST00000446044.1
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr1_+_11751748 0.03 ENST00000294485.5
DRAXIN
dorsal inhibitory axon guidance protein
chrX_+_28605516 0.03 ENST00000378993.1
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr14_-_22005343 0.03 ENST00000327430.3
SALL2
spalt-like transcription factor 2
chr1_-_186430222 0.03 ENST00000391997.2
PDC
phosducin
chr22_-_41258074 0.03 ENST00000307221.4
DNAJB7
DnaJ (Hsp40) homolog, subfamily B, member 7
chr15_+_63050785 0.03 ENST00000472902.1
TLN2
talin 2
chr2_-_225362533 0.03 ENST00000451538.1
CUL3
cullin 3
chr12_+_81101277 0.03 ENST00000228641.3
MYF6
myogenic factor 6 (herculin)
chr3_-_9291063 0.03 ENST00000383836.3
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr19_-_3479086 0.03 ENST00000587847.1
C19orf77
chromosome 19 open reading frame 77
chr19_+_56166360 0.03 ENST00000308924.4
U2AF2
U2 small nuclear RNA auxiliary factor 2
chr6_-_42690312 0.03 ENST00000230381.5
PRPH2
peripherin 2 (retinal degeneration, slow)
chr19_+_11457175 0.03 ENST00000458408.1
ENST00000586451.1
ENST00000588592.1
CCDC159
coiled-coil domain containing 159
chr17_+_72931876 0.03 ENST00000328801.4
OTOP3
otopetrin 3
chr5_-_58882219 0.03 ENST00000505453.1
ENST00000360047.5
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_-_50649192 0.03 ENST00000443053.2
ENST00000348721.3
CISH
cytokine inducible SH2-containing protein
chr21_+_33245548 0.03 ENST00000270112.2
HUNK
hormonally up-regulated Neu-associated kinase
chr11_-_8680383 0.03 ENST00000299550.6
TRIM66
tripartite motif containing 66
chr12_-_86650077 0.03 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr19_+_18208603 0.03 ENST00000262811.6
MAST3
microtubule associated serine/threonine kinase 3
chr9_+_34992846 0.03 ENST00000443266.1
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr10_-_74114714 0.03 ENST00000338820.3
ENST00000394903.2
ENST00000444643.2
DNAJB12
DnaJ (Hsp40) homolog, subfamily B, member 12
chr9_-_139361503 0.03 ENST00000453963.1
SEC16A
SEC16 homolog A (S. cerevisiae)
chr22_-_30867973 0.03 ENST00000402286.1
ENST00000401751.1
ENST00000539629.1
ENST00000403066.1
ENST00000215812.4
SEC14L3
SEC14-like 3 (S. cerevisiae)
chr14_-_23395623 0.02 ENST00000556043.1
PRMT5
protein arginine methyltransferase 5
chr19_+_7710774 0.02 ENST00000602355.1
STXBP2
syntaxin binding protein 2
chrM_+_10758 0.02 ENST00000361381.2
MT-ND4
mitochondrially encoded NADH dehydrogenase 4
chr3_-_190580404 0.02 ENST00000442080.1
GMNC
geminin coiled-coil domain containing
chr8_-_114449112 0.02 ENST00000455883.2
ENST00000352409.3
ENST00000297405.5
CSMD3
CUB and Sushi multiple domains 3
chr12_-_54779511 0.02 ENST00000551109.1
ENST00000546970.1
ZNF385A
zinc finger protein 385A
chr17_-_4689649 0.02 ENST00000441199.2
ENST00000416307.2
VMO1
vitelline membrane outer layer 1 homolog (chicken)
chr21_+_17443434 0.02 ENST00000400178.2
LINC00478
long intergenic non-protein coding RNA 478
chr10_-_21806759 0.02 ENST00000444772.3
SKIDA1
SKI/DACH domain containing 1
chr16_+_81272287 0.02 ENST00000425577.2
ENST00000564552.1
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr13_-_95131923 0.02 ENST00000377028.5
ENST00000446125.1
DCT
dopachrome tautomerase
chr19_-_44124019 0.02 ENST00000300811.3
ZNF428
zinc finger protein 428
chr12_-_66275350 0.02 ENST00000536648.1
RP11-366L20.2
Uncharacterized protein
chrX_-_153363188 0.02 ENST00000303391.6
MECP2
methyl CpG binding protein 2 (Rett syndrome)
chr19_-_55865908 0.02 ENST00000590900.1
COX6B2
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr7_-_111424462 0.02 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr1_+_62439037 0.02 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr14_-_101034811 0.02 ENST00000553553.1
BEGAIN
brain-enriched guanylate kinase-associated
chr8_-_10512569 0.02 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr6_-_66417107 0.02 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
EYS
eyes shut homolog (Drosophila)
chr12_-_53171128 0.02 ENST00000332411.2
KRT76
keratin 76
chrX_+_135279179 0.02 ENST00000370676.3
FHL1
four and a half LIM domains 1
chr21_+_17443521 0.02 ENST00000456342.1
LINC00478
long intergenic non-protein coding RNA 478
chr14_-_67981916 0.02 ENST00000357461.2
TMEM229B
transmembrane protein 229B
chr6_-_30658745 0.02 ENST00000376420.5
ENST00000376421.5
NRM
nurim (nuclear envelope membrane protein)
chr5_+_150040403 0.02 ENST00000517768.1
ENST00000297130.4
MYOZ3
myozenin 3
chr19_+_40877583 0.02 ENST00000596470.1
PLD3
phospholipase D family, member 3
chr15_+_79603479 0.02 ENST00000424155.2
ENST00000536821.1
TMED3
transmembrane emp24 protein transport domain containing 3
chrX_-_10588459 0.02 ENST00000380782.2
MID1
midline 1 (Opitz/BBB syndrome)
chr8_+_55528627 0.02 ENST00000220676.1
RP1
retinitis pigmentosa 1 (autosomal dominant)
chr7_+_80231466 0.02 ENST00000309881.7
ENST00000534394.1
CD36
CD36 molecule (thrombospondin receptor)
chr2_-_188312971 0.02 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
CALCRL
calcitonin receptor-like
chr1_-_151965048 0.02 ENST00000368809.1
S100A10
S100 calcium binding protein A10
chr2_+_33661382 0.02 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr11_+_128563652 0.02 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr8_-_145701718 0.02 ENST00000377317.4
FOXH1
forkhead box H1
chr4_-_68829226 0.02 ENST00000396188.2
TMPRSS11A
transmembrane protease, serine 11A
chr2_-_200715573 0.02 ENST00000420922.2
FTCDNL1
formiminotransferase cyclodeaminase N-terminal like
chr19_-_11457162 0.02 ENST00000590482.1
TMEM205
transmembrane protein 205
chr20_+_4702548 0.02 ENST00000305817.2
PRND
prion protein 2 (dublet)
chr6_-_154568815 0.02 ENST00000519344.1
IPCEF1
interaction protein for cytohesin exchange factors 1
chr6_+_106535455 0.02 ENST00000424894.1
PRDM1
PR domain containing 1, with ZNF domain
chr11_+_124735282 0.02 ENST00000397801.1
ROBO3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr1_+_81771806 0.02 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr3_+_111393501 0.02 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr18_+_616672 0.02 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr10_-_21186144 0.02 ENST00000377119.1
NEBL
nebulette
chr3_-_47950745 0.02 ENST00000429422.1
MAP4
microtubule-associated protein 4
chr5_-_33984741 0.02 ENST00000382102.3
ENST00000509381.1
ENST00000342059.3
ENST00000345083.5
SLC45A2
solute carrier family 45, member 2
chr11_-_128712362 0.02 ENST00000392664.2
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr10_+_24528108 0.02 ENST00000438429.1
KIAA1217
KIAA1217
chr13_-_79980315 0.02 ENST00000438737.2
RBM26
RNA binding motif protein 26
chr17_-_43209862 0.02 ENST00000322765.5
PLCD3
phospholipase C, delta 3
chr20_-_49307897 0.02 ENST00000535356.1
FAM65C
family with sequence similarity 65, member C
chr4_-_68829144 0.02 ENST00000508048.1
TMPRSS11A
transmembrane protease, serine 11A
chr11_-_111794446 0.01 ENST00000527950.1
CRYAB
crystallin, alpha B
chr11_-_71753188 0.01 ENST00000543009.1
NUMA1
nuclear mitotic apparatus protein 1
chr10_+_52750930 0.01 ENST00000401604.2
PRKG1
protein kinase, cGMP-dependent, type I
chr12_+_58138664 0.01 ENST00000257910.3
TSPAN31
tetraspanin 31
chr11_-_128894053 0.01 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr6_-_30899924 0.01 ENST00000359086.3
SFTA2
surfactant associated 2
chrM_+_8527 0.01 ENST00000361899.2
MT-ATP6
mitochondrially encoded ATP synthase 6
chrX_-_33357558 0.01 ENST00000288447.4
DMD
dystrophin
chr17_-_60885659 0.01 ENST00000311269.5
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr11_+_20044096 0.01 ENST00000533917.1
NAV2
neuron navigator 2
chr4_+_110769258 0.01 ENST00000594814.1
LRIT3
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3
chr10_-_104178857 0.01 ENST00000020673.5
PSD
pleckstrin and Sec7 domain containing
chrX_-_100129128 0.01 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
NOX1
NADPH oxidase 1
chr9_+_75229616 0.01 ENST00000340019.3
TMC1
transmembrane channel-like 1
chr5_+_145718587 0.01 ENST00000230732.4
POU4F3
POU class 4 homeobox 3
chr10_-_126849588 0.01 ENST00000411419.2
CTBP2
C-terminal binding protein 2
chr1_+_164528866 0.01 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr18_+_616711 0.01 ENST00000579494.1
CLUL1
clusterin-like 1 (retinal)
chr7_+_136553370 0.01 ENST00000445907.2
CHRM2
cholinergic receptor, muscarinic 2
chr7_-_83824169 0.01 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr17_-_60885700 0.01 ENST00000583600.1
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr1_+_209757051 0.01 ENST00000009105.1
ENST00000423146.1
ENST00000361322.2
CAMK1G
calcium/calmodulin-dependent protein kinase IG
chr3_+_191046810 0.01 ENST00000392455.3
ENST00000392456.3
CCDC50
coiled-coil domain containing 50
chr1_+_55505184 0.01 ENST00000302118.5
PCSK9
proprotein convertase subtilisin/kexin type 9
chr19_-_59066452 0.01 ENST00000312547.2
CHMP2A
charged multivesicular body protein 2A
chr12_+_70133152 0.01 ENST00000550536.1
ENST00000362025.5
RAB3IP
RAB3A interacting protein
chr18_-_21891460 0.01 ENST00000357041.4
OSBPL1A
oxysterol binding protein-like 1A
chr10_+_129785574 0.01 ENST00000430713.2
ENST00000471218.1
PTPRE
protein tyrosine phosphatase, receptor type, E
chr15_+_54901540 0.01 ENST00000539562.2
UNC13C
unc-13 homolog C (C. elegans)
chr9_+_18474098 0.01 ENST00000327883.7
ENST00000431052.2
ENST00000380570.4
ADAMTSL1
ADAMTS-like 1
chr1_+_202431859 0.01 ENST00000391959.3
ENST00000367270.4
PPP1R12B
protein phosphatase 1, regulatory subunit 12B

Network of associatons between targets according to the STRING database.

First level regulatory network of OTX2_CRX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.3 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.2 GO:1990637 response to prolactin(GO:1990637)
0.0 0.1 GO:0072738 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.0 0.1 GO:0003051 brain renin-angiotensin system(GO:0002035) angiotensin-mediated drinking behavior(GO:0003051)
0.0 0.2 GO:0048619 embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.2 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.2 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.0 GO:0021524 visceral motor neuron differentiation(GO:0021524) cardiac cell fate determination(GO:0060913)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0002046 opsin binding(GO:0002046)
0.0 0.2 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.0 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.0 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors