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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NKX2-8

Z-value: 0.68

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Transcription factors associated with NKX2-8

Gene Symbol Gene ID Gene Info
ENSG00000136327.6 NK2 homeobox 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-8hg19_v2_chr14_-_37051798_37051831-0.157.7e-01Click!

Activity profile of NKX2-8 motif

Sorted Z-values of NKX2-8 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_27998689 0.82 ENST00000339145.4
ENST00000362020.4
ENST00000361157.6
interferon, alpha-inducible protein 6
chr2_-_25451065 0.53 ENST00000606328.1
RP11-458N5.1
chr17_+_67590125 0.53 ENST00000591334.1
AC003051.1
chrX_+_115567767 0.42 ENST00000371900.4
solute carrier family 6 (amino acid transporter), member 14
chr5_-_176056974 0.39 ENST00000510387.1
ENST00000506696.1
synuclein, beta
chr1_+_10057274 0.38 ENST00000294435.7
retinol binding protein 7, cellular
chr3_+_177545563 0.32 ENST00000434309.1
RP11-91K9.1
chr22_+_38609538 0.31 ENST00000407965.1
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr6_+_43968306 0.31 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
chromosome 6 open reading frame 223
chr14_-_24732403 0.28 ENST00000206765.6
transglutaminase 1
chr2_-_36779411 0.28 ENST00000406220.1
Uncharacterized protein
chr3_+_172361483 0.27 ENST00000598405.1
HCG1787166; PRO1163; Uncharacterized protein
chr16_+_23194033 0.25 ENST00000300061.2
sodium channel, non-voltage-gated 1, gamma subunit
chr6_+_41010293 0.25 ENST00000373161.1
ENST00000373158.2
ENST00000470917.1
translocator protein 2
chr2_+_119699864 0.23 ENST00000541757.1
ENST00000412481.1
macrophage receptor with collagenous structure
chr17_+_76210367 0.22 ENST00000592734.1
ENST00000587746.1
baculoviral IAP repeat containing 5
chr2_-_159313214 0.20 ENST00000409889.1
ENST00000283233.5
ENST00000536771.1
coiled-coil domain containing 148
chr3_+_126423045 0.20 ENST00000290913.3
ENST00000508789.1
coiled-coil-helix-coiled-coil-helix domain containing 6
chr14_-_24732368 0.20 ENST00000544573.1
transglutaminase 1
chr7_-_127671674 0.19 ENST00000478726.1
leucine rich repeat containing 4
chr12_+_49658855 0.19 ENST00000549183.1
tubulin, alpha 1c
chr2_+_119699742 0.17 ENST00000327097.4
macrophage receptor with collagenous structure
chr8_+_107593198 0.17 ENST00000517686.1
oxidation resistance 1
chr14_+_58894404 0.17 ENST00000554463.1
ENST00000555833.1
KIAA0586
chr11_-_128457446 0.16 ENST00000392668.4
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr3_-_16524357 0.16 ENST00000432519.1
raftlin, lipid raft linker 1
chr1_-_95007193 0.16 ENST00000370207.4
ENST00000334047.7
coagulation factor III (thromboplastin, tissue factor)
chr1_+_228337553 0.15 ENST00000366714.2
gap junction protein, gamma 2, 47kDa
chr2_+_101591314 0.15 ENST00000450763.1
neuronal PAS domain protein 2
chr2_-_68547061 0.15 ENST00000263655.3
cannabinoid receptor interacting protein 1
chr4_+_76481258 0.15 ENST00000311623.4
ENST00000435974.2
chromosome 4 open reading frame 26
chr21_+_33671160 0.15 ENST00000303645.5
melanocortin 2 receptor accessory protein
chr3_+_239652 0.15 ENST00000435603.1
cell adhesion molecule L1-like
chr18_-_72920372 0.14 ENST00000581620.1
ENST00000582437.1
zinc binding alcohol dehydrogenase domain containing 2
chr12_+_13349711 0.14 ENST00000538364.1
ENST00000396301.3
epithelial membrane protein 1
chr7_-_766879 0.14 ENST00000537384.1
ENST00000417852.1
protein kinase, cAMP-dependent, regulatory, type I, beta
chr12_+_66218903 0.14 ENST00000393577.3
high mobility group AT-hook 2
chr8_+_105602961 0.13 ENST00000521923.1
Uncharacterized protein
chr3_+_67048721 0.13 ENST00000295568.4
ENST00000484414.1
ENST00000460576.1
ENST00000417314.2
kelch repeat and BTB (POZ) domain containing 8
chr18_+_44497455 0.13 ENST00000592005.1
katanin p60 subunit A-like 2
chr17_+_61086917 0.13 ENST00000424789.2
ENST00000389520.4
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chrX_+_48681768 0.12 ENST00000430858.1
histone deacetylase 6
chr22_+_39101728 0.12 ENST00000216044.5
ENST00000484657.1
GTP binding protein 1
chr8_-_29120604 0.12 ENST00000521515.1
kinesin family member 13B
chr15_-_60683326 0.12 ENST00000559350.1
ENST00000558986.1
ENST00000560389.1
annexin A2
chr22_-_32341336 0.11 ENST00000248984.3
chromosome 22 open reading frame 24
chr15_-_35047166 0.10 ENST00000290374.4
gap junction protein, delta 2, 36kDa
chr12_+_7941989 0.10 ENST00000229307.4
Nanog homeobox
chr4_-_100485143 0.10 ENST00000394877.3
tRNA methyltransferase 10 homolog A (S. cerevisiae)
chr8_-_29120580 0.10 ENST00000524189.1
kinesin family member 13B
chr16_+_58426296 0.10 ENST00000426538.2
ENST00000328514.7
ENST00000318129.5
GINS complex subunit 3 (Psf3 homolog)
chrM_+_8366 0.10 ENST00000361851.1
mitochondrially encoded ATP synthase 8
chrX_-_69479654 0.10 ENST00000374519.2
pyrimidinergic receptor P2Y, G-protein coupled, 4
chr19_-_39881669 0.10 ENST00000221266.7
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr10_-_135171178 0.10 ENST00000368551.1
fucose mutarotase
chr18_+_3450161 0.09 ENST00000551402.1
ENST00000577543.1
TGFB-induced factor homeobox 1
chr1_+_180165672 0.09 ENST00000443059.1
quiescin Q6 sulfhydryl oxidase 1
chr5_-_95158644 0.09 ENST00000237858.6
glutaredoxin (thioltransferase)
chr21_+_33671264 0.09 ENST00000339944.4
melanocortin 2 receptor accessory protein
chr3_-_52739670 0.09 ENST00000497953.1
glycosyltransferase 8 domain containing 1
chr3_-_114790179 0.09 ENST00000462705.1
zinc finger and BTB domain containing 20
chr7_-_95025661 0.09 ENST00000542556.1
ENST00000265627.5
ENST00000427422.1
ENST00000451904.1
paraoxonase 1
paraoxonase 3
chr11_+_59705928 0.09 ENST00000398992.1
oocyte secreted protein 1
chr20_-_48747662 0.09 ENST00000371656.2
transmembrane protein 189
chr18_+_13382553 0.09 ENST00000586222.1
low density lipoprotein receptor class A domain containing 4
chr8_+_23430157 0.09 ENST00000399967.3
FP15737
chr6_-_133084580 0.09 ENST00000525270.1
ENST00000530536.1
ENST00000524919.1
vanin 2
chr4_-_7873713 0.08 ENST00000382543.3
actin filament associated protein 1
chr5_+_35852797 0.08 ENST00000508941.1
interleukin 7 receptor
chr16_+_67034466 0.08 ENST00000535696.1
carboxylesterase 4A
chr16_+_67034456 0.08 ENST00000540579.1
carboxylesterase 4A
chr14_-_58894332 0.08 ENST00000395159.2
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr8_-_81083341 0.08 ENST00000519303.2
tumor protein D52
chr4_-_819901 0.08 ENST00000304062.6
complexin 1
chr16_+_29674540 0.08 ENST00000436527.1
ENST00000360121.3
ENST00000449759.1
sialophorin
quinolinate phosphoribosyltransferase
chr17_+_7591639 0.07 ENST00000396463.2
WD repeat containing, antisense to TP53
chr12_-_10320190 0.07 ENST00000543993.1
ENST00000339968.6
oxidized low density lipoprotein (lectin-like) receptor 1
chr7_-_127672146 0.07 ENST00000476782.1
leucine rich repeat containing 4
chr14_-_58894223 0.07 ENST00000555593.1
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr11_+_18417948 0.07 ENST00000542179.1
lactate dehydrogenase A
chr4_-_100485183 0.07 ENST00000394876.2
tRNA methyltransferase 10 homolog A (S. cerevisiae)
chr10_-_14596140 0.07 ENST00000496330.1
family with sequence similarity 107, member B
chr1_+_151512775 0.07 ENST00000368849.3
ENST00000392712.3
ENST00000353024.3
ENST00000368848.2
ENST00000538902.1
tuftelin 1
chr12_+_60058458 0.07 ENST00000548610.1
solute carrier family 16 (monocarboxylate transporter), member 7
chr1_+_55464600 0.06 ENST00000371265.4
Bartter syndrome, infantile, with sensorineural deafness (Barttin)
chr3_+_111717511 0.06 ENST00000478951.1
ENST00000393917.2
transgelin 3
chr6_-_137113604 0.06 ENST00000359015.4
mitogen-activated protein kinase kinase kinase 5
chr17_-_9808887 0.06 ENST00000226193.5
recoverin
chr7_+_18330035 0.06 ENST00000413509.2
histone deacetylase 9
chr16_-_3767506 0.06 ENST00000538171.1
TNF receptor-associated protein 1
chr11_-_72353451 0.06 ENST00000376450.3
phosphodiesterase 2A, cGMP-stimulated
chr2_+_204801471 0.06 ENST00000316386.6
ENST00000435193.1
inducible T-cell co-stimulator
chrM_+_8527 0.06 ENST00000361899.2
mitochondrially encoded ATP synthase 6
chr11_-_72353494 0.06 ENST00000544570.1
phosphodiesterase 2A, cGMP-stimulated
chr6_+_30844192 0.06 ENST00000502955.1
ENST00000505066.1
discoidin domain receptor tyrosine kinase 1
chr9_+_131873842 0.06 ENST00000417728.1
protein phosphatase 2A activator, regulatory subunit 4
chr7_+_30634297 0.06 ENST00000389266.3
glycyl-tRNA synthetase
chr20_+_47835884 0.06 ENST00000371764.4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
chr1_+_41157361 0.06 ENST00000427410.2
ENST00000447388.3
ENST00000425457.2
ENST00000453631.1
ENST00000456393.2
nuclear transcription factor Y, gamma
chr12_-_49504449 0.06 ENST00000547675.1
limb development membrane protein 1-like
chr8_-_144679264 0.05 ENST00000531953.1
ENST00000526133.1
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr3_-_8811288 0.05 ENST00000316793.3
ENST00000431493.1
oxytocin receptor
chr21_-_35899113 0.05 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
regulator of calcineurin 1
chr19_+_34856141 0.05 ENST00000586425.1
glucose-6-phosphate isomerase
chr4_-_153601136 0.05 ENST00000504064.1
ENST00000304385.3
transmembrane protein 154
chr1_+_154401791 0.05 ENST00000476006.1
interleukin 6 receptor
chr19_-_38720354 0.05 ENST00000416611.1
D4, zinc and double PHD fingers family 1
chrX_-_63450480 0.05 ENST00000362002.2
ankyrin repeat and SOCS box containing 12
chr16_-_66952779 0.05 ENST00000570262.1
ENST00000394055.3
ENST00000299752.4
cadherin 16, KSP-cadherin
chr16_-_30441293 0.05 ENST00000565758.1
ENST00000567983.1
ENST00000319285.4
dCTP pyrophosphatase 1
chr3_+_111717600 0.05 ENST00000273368.4
transgelin 3
chr5_+_176692466 0.05 ENST00000508029.1
ENST00000503056.1
nuclear receptor binding SET domain protein 1
chr2_-_151905288 0.05 ENST00000409243.1
HCG1817310; Uncharacterized protein
chr16_-_3767551 0.05 ENST00000246957.5
TNF receptor-associated protein 1
chr6_-_32806506 0.05 ENST00000374897.2
ENST00000452392.2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Uncharacterized protein
chr18_-_44497308 0.05 ENST00000585916.1
ENST00000324794.7
ENST00000545673.1
protein inhibitor of activated STAT, 2
chr19_-_44259053 0.05 ENST00000601170.1
SMG9 nonsense mediated mRNA decay factor
chr1_+_74701062 0.05 ENST00000326637.3
TNNI3 interacting kinase
chrX_-_64196307 0.05 ENST00000545618.1
zinc finger, C4H2 domain containing
chr8_+_128426535 0.05 ENST00000465342.2
POU class 5 homeobox 1B
chr15_-_77363375 0.05 ENST00000559494.1
tetraspanin 3
chr17_-_62502399 0.05 ENST00000450599.2
ENST00000585060.1
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr6_+_34433844 0.05 ENST00000244458.2
ENST00000374043.2
protein kinase C and casein kinase substrate in neurons 1
chr8_-_125551278 0.04 ENST00000519232.1
ENST00000523888.1
ENST00000522810.1
ENST00000519548.1
ENST00000517678.1
ENST00000605953.1
ENST00000276692.6
TatD DNase domain containing 1
chr20_-_57089934 0.04 ENST00000439429.1
ENST00000371149.3
adenomatosis polyposis coli down-regulated 1-like
chr17_-_62502639 0.04 ENST00000225792.5
ENST00000581697.1
ENST00000584279.1
ENST00000577922.1
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr2_+_62132800 0.04 ENST00000538736.1
copper metabolism (Murr1) domain containing 1
chr17_+_37784749 0.04 ENST00000394265.1
ENST00000394267.2
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr16_-_66952742 0.04 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
cadherin 16, KSP-cadherin
chrX_-_9754333 0.04 ENST00000447366.1
G protein-coupled receptor 143
chr11_-_67141640 0.04 ENST00000533438.1
cardiotrophin-like cytokine factor 1
chr3_-_196242233 0.04 ENST00000397537.2
single-pass membrane protein with coiled-coil domains 1
chr1_-_217262969 0.04 ENST00000361525.3
estrogen-related receptor gamma
chr12_+_13349650 0.04 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
epithelial membrane protein 1
chr6_-_32145861 0.04 ENST00000336984.6
1-acylglycerol-3-phosphate O-acyltransferase 1
chr2_-_151395525 0.04 ENST00000439275.1
Rho family GTPase 3
chr10_-_118032697 0.04 ENST00000439649.3
GDNF family receptor alpha 1
chr3_-_116163830 0.04 ENST00000333617.4
limbic system-associated membrane protein
chr15_+_74911430 0.04 ENST00000562670.1
ENST00000564096.1
CDC-like kinase 3
chr19_+_52074502 0.04 ENST00000545217.1
ENST00000262259.2
ENST00000596504.1
zinc finger protein 175
chr3_-_58613323 0.04 ENST00000474531.1
ENST00000465970.1
family with sequence similarity 107, member A
chr3_-_73673991 0.04 ENST00000308537.4
ENST00000263666.4
PDZ domain containing ring finger 3
chr10_+_71078595 0.04 ENST00000359426.6
hexokinase 1
chr1_+_16083098 0.04 ENST00000496928.2
ENST00000508310.1
filamin binding LIM protein 1
chr17_-_62503015 0.04 ENST00000581806.1
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr17_+_73455788 0.04 ENST00000581519.1
KIAA0195
chr1_-_94147385 0.04 ENST00000260502.6
breast cancer anti-estrogen resistance 3
chr19_+_34856078 0.04 ENST00000589399.1
ENST00000589640.1
ENST00000591204.1
glucose-6-phosphate isomerase
chr19_-_44259136 0.03 ENST00000270066.6
SMG9 nonsense mediated mRNA decay factor
chrX_-_110039286 0.03 ENST00000434224.1
chordin-like 1
chr1_-_217262933 0.03 ENST00000359162.2
estrogen-related receptor gamma
chr15_-_77363513 0.03 ENST00000267970.4
tetraspanin 3
chr5_-_179107975 0.03 ENST00000376974.4
chibby homolog 3 (Drosophila)
chr8_+_67341239 0.03 ENST00000320270.2
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr1_+_224301787 0.03 ENST00000366862.5
ENST00000424254.2
F-box protein 28
chr4_-_100484825 0.03 ENST00000273962.3
ENST00000514547.1
ENST00000455368.2
tRNA methyltransferase 10 homolog A (S. cerevisiae)
chr14_+_76618242 0.03 ENST00000557542.1
ENST00000557263.1
ENST00000557207.1
ENST00000312858.5
ENST00000261530.7
G patch domain containing 2-like
chr3_+_173302222 0.03 ENST00000361589.4
neuroligin 1
chr1_+_12040238 0.03 ENST00000444836.1
ENST00000235329.5
mitofusin 2
chr15_+_86686953 0.03 ENST00000421325.2
ATP/GTP binding protein-like 1
chr6_+_143772060 0.03 ENST00000367591.4
peroxisomal biogenesis factor 3
chr12_-_49504655 0.03 ENST00000551782.1
ENST00000267102.8
limb development membrane protein 1-like
chr17_+_46184911 0.03 ENST00000580219.1
ENST00000452859.2
ENST00000393405.2
ENST00000439357.2
ENST00000359238.2
sorting nexin 11
chrX_-_48776292 0.03 ENST00000376509.4
pim-2 oncogene
chrX_-_110655306 0.03 ENST00000371993.2
doublecortin
chr2_-_136288740 0.03 ENST00000264159.6
ENST00000536680.1
zinc finger, RAN-binding domain containing 3
chr3_-_187455680 0.03 ENST00000438077.1
B-cell CLL/lymphoma 6
chr17_-_46178527 0.03 ENST00000393408.3
chromobox homolog 1
chr12_-_118406777 0.03 ENST00000339824.5
kinase suppressor of ras 2
chr2_+_207024306 0.03 ENST00000236957.5
ENST00000392221.1
ENST00000392222.2
ENST00000445505.1
eukaryotic translation elongation factor 1 beta 2
chr6_+_69942298 0.03 ENST00000238918.8
brain-specific angiogenesis inhibitor 3
chr15_-_77363441 0.03 ENST00000346495.2
ENST00000424443.3
ENST00000561277.1
tetraspanin 3
chr17_+_62503073 0.02 ENST00000580188.1
ENST00000581056.1
centrosomal protein 95kDa
chr12_-_75603202 0.02 ENST00000393288.2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr17_-_33390667 0.02 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr8_+_27182862 0.02 ENST00000521164.1
ENST00000346049.5
protein tyrosine kinase 2 beta
chr11_-_104827425 0.02 ENST00000393150.3
caspase 4, apoptosis-related cysteine peptidase
chr13_+_46039037 0.02 ENST00000349995.5
component of oligomeric golgi complex 3
chr15_+_40453204 0.02 ENST00000287598.6
ENST00000412359.3
BUB1 mitotic checkpoint serine/threonine kinase B
chr17_+_7591747 0.02 ENST00000534050.1
WD repeat containing, antisense to TP53
chr19_-_11347173 0.02 ENST00000587656.1
dedicator of cytokinesis 6
chr3_-_53164423 0.02 ENST00000467048.1
ENST00000394738.3
ENST00000296292.3
RFT1 homolog (S. cerevisiae)
chr7_-_92855762 0.02 ENST00000453812.2
ENST00000394468.2
HEPACAM family member 2
chr1_-_104239302 0.02 ENST00000446703.1
amylase, alpha 1B (salivary)
chr3_-_114343768 0.02 ENST00000393785.2
zinc finger and BTB domain containing 20
chr2_-_68547019 0.02 ENST00000409862.1
cannabinoid receptor interacting protein 1
chr7_-_156803329 0.02 ENST00000252971.6
motor neuron and pancreas homeobox 1
chr17_-_79623597 0.02 ENST00000574024.1
ENST00000331056.5
phosphodiesterase 6G, cGMP-specific, rod, gamma
chr1_+_41157421 0.02 ENST00000372654.1
nuclear transcription factor Y, gamma
chr1_-_155006224 0.02 ENST00000368424.3
DC-STAMP domain containing 2
chr22_+_21213771 0.02 ENST00000439214.1
synaptosomal-associated protein, 29kDa
chr12_-_12837423 0.02 ENST00000540510.1
G protein-coupled receptor 19
chr15_-_99057551 0.02 ENST00000558256.1
family with sequence similarity 169, member B
chr2_-_207023918 0.02 ENST00000455934.2
ENST00000449699.1
ENST00000454195.1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr1_+_76251912 0.02 ENST00000370826.3
Rab geranylgeranyltransferase, beta subunit
chr7_+_30811004 0.02 ENST00000265299.6
family with sequence similarity 188, member B
chr5_+_74011328 0.02 ENST00000513336.1
hexosaminidase B (beta polypeptide)
chr11_+_64808675 0.02 ENST00000529996.1
SAC3 domain containing 1
chr6_-_55740352 0.02 ENST00000370830.3
bone morphogenetic protein 5
chr18_-_56296182 0.02 ENST00000361673.3
alpha-kinase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:1904180 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.1 0.5 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 0.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.1 GO:0031049 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.0 0.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.1 GO:0070845 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.1 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.1 GO:0044035 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.2 GO:0030578 PML body organization(GO:0030578)
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.1 GO:0060455 positive regulation of norepinephrine secretion(GO:0010701) negative regulation of gastric acid secretion(GO:0060455)
0.0 0.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.0 0.1 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0 0.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.0 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.1 GO:0015966 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.0 0.3 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.1 GO:0060180 female mating behavior(GO:0060180)
0.0 0.4 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.1 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.1 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.3 GO:0007567 parturition(GO:0007567)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.1 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.1 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.0 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 0.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.1 GO:0035501 MH1 domain binding(GO:0035501)
0.0 0.1 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.1 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.0 0.4 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.1 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.3 GO:0016918 retinal binding(GO:0016918)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.2 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.0 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.0 GO:0035643 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.4 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly