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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NKX2-5

Z-value: 0.52

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Transcription factors associated with NKX2-5

Gene Symbol Gene ID Gene Info
NKX2-5
ENSG00000183072.9 NK2 homeobox 5

Activity profile of NKX2-5 motif

Sorted Z-values of NKX2-5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_56778635 0.31 ENST00000423391.1
ACTBL2
actin, beta-like 2
chr12_-_123717711 0.29 ENST00000537854.1
MPHOSPH9
M-phase phosphoprotein 9
chr11_-_9482010 0.26 ENST00000596206.1
AC132192.1
LOC644656 protein; Uncharacterized protein
chr8_-_95220775 0.23 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr16_-_30134441 0.20 ENST00000395200.1
MAPK3
mitogen-activated protein kinase 3
chr16_+_31483451 0.17 ENST00000565360.1
ENST00000361773.3
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr12_+_123717967 0.16 ENST00000536130.1
ENST00000546132.1
C12orf65
chromosome 12 open reading frame 65
chr16_-_30134266 0.16 ENST00000484663.1
ENST00000478356.1
MAPK3
mitogen-activated protein kinase 3
chr18_+_19668021 0.16 ENST00000579830.1
RP11-595B24.2
Uncharacterized protein
chr16_+_77233294 0.15 ENST00000378644.4
SYCE1L
synaptonemal complex central element protein 1-like
chr14_+_78227105 0.15 ENST00000439131.2
ENST00000355883.3
ENST00000557011.1
ENST00000556047.1
C14orf178
chromosome 14 open reading frame 178
chrX_-_83442915 0.15 ENST00000262752.2
ENST00000543399.1
RPS6KA6
ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr7_-_24957699 0.14 ENST00000441059.1
ENST00000415162.1
OSBPL3
oxysterol binding protein-like 3
chr17_-_55911970 0.13 ENST00000581805.1
ENST00000580960.1
RP11-60A24.3
RP11-60A24.3
chr1_+_159796534 0.13 ENST00000289707.5
SLAMF8
SLAM family member 8
chr16_-_30134524 0.13 ENST00000395202.1
ENST00000395199.3
ENST00000263025.4
ENST00000322266.5
ENST00000403394.1
MAPK3
mitogen-activated protein kinase 3
chr9_+_35906176 0.13 ENST00000354323.2
HRCT1
histidine rich carboxyl terminus 1
chr2_+_219646462 0.13 ENST00000258415.4
CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1
chr18_+_42260059 0.11 ENST00000426838.4
SETBP1
SET binding protein 1
chr1_+_32671236 0.11 ENST00000537469.1
ENST00000291358.6
IQCC
IQ motif containing C
chr14_+_21467414 0.11 ENST00000554422.1
ENST00000298681.4
SLC39A2
solute carrier family 39 (zinc transporter), member 2
chr1_+_159796589 0.10 ENST00000368104.4
SLAMF8
SLAM family member 8
chr6_-_112115103 0.10 ENST00000462598.3
FYN
FYN oncogene related to SRC, FGR, YES
chr2_+_48541776 0.09 ENST00000413569.1
ENST00000340553.3
FOXN2
forkhead box N2
chr17_-_982198 0.09 ENST00000571945.1
ENST00000536794.2
ABR
active BCR-related
chr16_+_68344877 0.09 ENST00000566657.1
ENST00000565745.1
ENST00000569571.1
ENST00000569047.3
ENST00000449359.3
PRMT7
protein arginine methyltransferase 7
chr7_+_99775366 0.09 ENST00000394018.2
ENST00000416412.1
STAG3
stromal antigen 3
chr1_-_11907829 0.09 ENST00000376480.3
NPPA
natriuretic peptide A
chr12_+_95867727 0.09 ENST00000323666.5
ENST00000546753.1
METAP2
methionyl aminopeptidase 2
chr2_+_152214098 0.08 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chrX_+_86772787 0.08 ENST00000373114.4
KLHL4
kelch-like family member 4
chr6_+_26273144 0.08 ENST00000377733.2
HIST1H2BI
histone cluster 1, H2bi
chr1_+_114472222 0.08 ENST00000369558.1
ENST00000369561.4
HIPK1
homeodomain interacting protein kinase 1
chr10_+_86184676 0.08 ENST00000543283.1
CCSER2
coiled-coil serine-rich protein 2
chr4_-_153700864 0.08 ENST00000304337.2
TIGD4
tigger transposable element derived 4
chr16_+_8814563 0.07 ENST00000425191.2
ENST00000569156.1
ABAT
4-aminobutyrate aminotransferase
chr15_+_42696992 0.07 ENST00000561817.1
CAPN3
calpain 3, (p94)
chr9_+_33265011 0.07 ENST00000419016.2
CHMP5
charged multivesicular body protein 5
chr9_+_118950325 0.07 ENST00000534838.1
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr11_+_18417948 0.07 ENST00000542179.1
LDHA
lactate dehydrogenase A
chr1_-_113160826 0.07 ENST00000538187.1
ENST00000369664.1
ST7L
suppression of tumorigenicity 7 like
chr14_+_23654525 0.07 ENST00000399910.1
ENST00000492621.1
C14orf164
chromosome 14 open reading frame 164
chr17_+_45973516 0.07 ENST00000376741.4
SP2
Sp2 transcription factor
chr2_+_201936707 0.07 ENST00000433898.1
ENST00000454214.1
NDUFB3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr2_-_175499294 0.07 ENST00000392547.2
WIPF1
WAS/WASL interacting protein family, member 1
chr15_+_42697018 0.06 ENST00000397204.4
CAPN3
calpain 3, (p94)
chr12_-_49259643 0.06 ENST00000309739.5
RND1
Rho family GTPase 1
chr4_+_110769258 0.06 ENST00000594814.1
LRIT3
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3
chr7_-_38969150 0.06 ENST00000418457.2
VPS41
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr9_+_33264861 0.06 ENST00000223500.8
CHMP5
charged multivesicular body protein 5
chr22_-_33968239 0.06 ENST00000452586.2
ENST00000421768.1
LARGE
like-glycosyltransferase
chr2_-_96874553 0.06 ENST00000337288.5
ENST00000443962.1
STARD7
StAR-related lipid transfer (START) domain containing 7
chr15_-_42840961 0.06 ENST00000563454.1
ENST00000397130.3
ENST00000570160.1
ENST00000323443.2
LRRC57
leucine rich repeat containing 57
chr5_+_55147205 0.06 ENST00000396836.2
ENST00000396834.1
ENST00000447346.2
ENST00000359040.5
IL31RA
interleukin 31 receptor A
chr6_-_27279949 0.05 ENST00000444565.1
ENST00000377451.2
POM121L2
POM121 transmembrane nucleoporin-like 2
chr6_+_31916733 0.05 ENST00000483004.1
CFB
complement factor B
chr5_-_138730817 0.05 ENST00000434752.2
PROB1
proline-rich basic protein 1
chr7_-_128415844 0.05 ENST00000249389.2
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chrX_-_142722897 0.05 ENST00000338017.4
SLITRK4
SLIT and NTRK-like family, member 4
chr8_-_10588010 0.05 ENST00000304501.1
SOX7
SRY (sex determining region Y)-box 7
chr3_+_125694347 0.05 ENST00000505382.1
ENST00000511082.1
ROPN1B
rhophilin associated tail protein 1B
chr11_-_73689037 0.05 ENST00000544615.1
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr5_+_74062806 0.05 ENST00000296802.5
NSA2
NSA2 ribosome biogenesis homolog (S. cerevisiae)
chr12_+_113354341 0.05 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr3_+_46283863 0.05 ENST00000545097.1
ENST00000541018.1
CCR3
chemokine (C-C motif) receptor 3
chr1_+_26606608 0.05 ENST00000319041.6
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr17_+_46048376 0.05 ENST00000338399.4
CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr11_+_118754475 0.05 ENST00000292174.4
CXCR5
chemokine (C-X-C motif) receptor 5
chr17_+_4699439 0.05 ENST00000270586.3
PSMB6
proteasome (prosome, macropain) subunit, beta type, 6
chrX_+_86772707 0.05 ENST00000373119.4
KLHL4
kelch-like family member 4
chr1_-_26232951 0.05 ENST00000426559.2
ENST00000455785.2
STMN1
stathmin 1
chr3_+_108321623 0.05 ENST00000497905.1
ENST00000463306.1
DZIP3
DAZ interacting zinc finger protein 3
chr11_+_18417813 0.05 ENST00000540430.1
ENST00000379412.5
LDHA
lactate dehydrogenase A
chr10_+_73156664 0.05 ENST00000398809.4
ENST00000398842.3
ENST00000461841.3
ENST00000299366.7
CDH23
cadherin-related 23
chr5_+_140345820 0.05 ENST00000289269.5
PCDHAC2
protocadherin alpha subfamily C, 2
chr2_-_220041617 0.05 ENST00000451647.1
ENST00000360507.5
CNPPD1
cyclin Pas1/PHO80 domain containing 1
chr4_+_113970772 0.05 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2
ankyrin 2, neuronal
chr1_-_160040038 0.04 ENST00000368089.3
KCNJ10
potassium inwardly-rectifying channel, subfamily J, member 10
chr15_-_60683326 0.04 ENST00000559350.1
ENST00000558986.1
ENST00000560389.1
ANXA2
annexin A2
chr3_-_47950745 0.04 ENST00000429422.1
MAP4
microtubule-associated protein 4
chr17_+_53342311 0.04 ENST00000226067.5
HLF
hepatic leukemia factor
chr10_-_81320151 0.04 ENST00000372325.2
ENST00000372327.5
ENST00000417041.1
SFTPA2
surfactant protein A2
chr1_+_211433275 0.04 ENST00000367005.4
RCOR3
REST corepressor 3
chr18_+_42260861 0.04 ENST00000282030.5
SETBP1
SET binding protein 1
chr2_+_201936458 0.04 ENST00000237889.4
NDUFB3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr10_-_27529486 0.04 ENST00000375888.1
ACBD5
acyl-CoA binding domain containing 5
chr3_-_107941209 0.04 ENST00000492106.1
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr17_+_74261413 0.04 ENST00000587913.1
UBALD2
UBA-like domain containing 2
chr15_-_81282133 0.04 ENST00000261758.4
MESDC2
mesoderm development candidate 2
chr1_-_149982624 0.04 ENST00000417191.1
ENST00000369135.4
OTUD7B
OTU domain containing 7B
chr1_+_27153173 0.04 ENST00000374142.4
ZDHHC18
zinc finger, DHHC-type containing 18
chr19_-_10946871 0.04 ENST00000589638.1
TMED1
transmembrane emp24 protein transport domain containing 1
chr9_-_34048873 0.04 ENST00000449054.1
ENST00000379239.4
ENST00000539807.1
ENST00000379238.1
ENST00000418786.2
ENST00000360802.1
ENST00000412543.1
UBAP2
ubiquitin associated protein 2
chr13_+_95364963 0.04 ENST00000438290.2
SOX21-AS1
SOX21 antisense RNA 1 (head to head)
chrX_-_14047996 0.04 ENST00000380523.4
ENST00000398355.3
GEMIN8
gem (nuclear organelle) associated protein 8
chr9_-_14313641 0.04 ENST00000380953.1
NFIB
nuclear factor I/B
chr2_+_136289030 0.04 ENST00000409478.1
ENST00000264160.4
ENST00000329971.3
ENST00000438014.1
R3HDM1
R3H domain containing 1
chr3_+_45984947 0.04 ENST00000304552.4
CXCR6
chemokine (C-X-C motif) receptor 6
chr14_-_68159152 0.03 ENST00000554035.1
RDH11
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
chr17_-_40169659 0.03 ENST00000457167.4
DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr3_+_125687987 0.03 ENST00000514116.1
ENST00000251776.4
ENST00000504401.1
ENST00000513830.1
ENST00000508088.1
ROPN1B
rhophilin associated tail protein 1B
chr11_-_118436707 0.03 ENST00000264020.2
ENST00000264021.3
IFT46
intraflagellar transport 46 homolog (Chlamydomonas)
chr14_-_75179774 0.03 ENST00000555249.1
ENST00000556202.1
ENST00000356357.4
ENST00000338772.5
AREL1
AC007956.1
apoptosis resistant E3 ubiquitin protein ligase 1
Full-length cDNA 5-PRIME end of clone CS0CAP004YO05 of Thymus of Homo sapiens (human); Uncharacterized protein
chr17_-_13505219 0.03 ENST00000284110.1
HS3ST3A1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr3_-_107941230 0.03 ENST00000264538.3
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr5_+_78407602 0.03 ENST00000274353.5
ENST00000524080.1
BHMT
betaine--homocysteine S-methyltransferase
chrX_+_11777671 0.03 ENST00000380693.3
ENST00000380692.2
MSL3
male-specific lethal 3 homolog (Drosophila)
chr12_-_53097247 0.03 ENST00000341809.3
ENST00000537195.1
KRT77
keratin 77
chr8_+_132916318 0.03 ENST00000254624.5
ENST00000522709.1
EFR3A
EFR3 homolog A (S. cerevisiae)
chr19_+_39926791 0.03 ENST00000594990.1
SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr5_-_171615315 0.03 ENST00000176763.5
STK10
serine/threonine kinase 10
chr9_+_133986782 0.03 ENST00000372301.2
AIF1L
allograft inflammatory factor 1-like
chr7_+_99775520 0.03 ENST00000317296.5
ENST00000422690.1
ENST00000439782.1
STAG3
stromal antigen 3
chr4_-_168155417 0.03 ENST00000511269.1
ENST00000506697.1
ENST00000512042.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr17_+_40811283 0.03 ENST00000251412.7
TUBG2
tubulin, gamma 2
chr15_-_74726283 0.03 ENST00000543145.2
SEMA7A
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr12_-_371994 0.03 ENST00000343164.4
ENST00000436453.1
ENST00000445055.2
ENST00000546319.1
SLC6A13
solute carrier family 6 (neurotransmitter transporter), member 13
chr4_+_2470664 0.03 ENST00000314289.8
ENST00000541204.1
ENST00000502316.1
ENST00000507247.1
ENST00000509258.1
ENST00000511859.1
RNF4
ring finger protein 4
chr5_+_140729649 0.03 ENST00000523390.1
PCDHGB1
protocadherin gamma subfamily B, 1
chr16_+_68344981 0.03 ENST00000441236.1
ENST00000348497.4
ENST00000339507.5
PRMT7
protein arginine methyltransferase 7
chr1_-_55352834 0.03 ENST00000371269.3
DHCR24
24-dehydrocholesterol reductase
chr16_-_3149278 0.03 ENST00000575108.1
ENST00000576483.1
ENST00000538082.2
ENST00000576985.1
ZSCAN10
zinc finger and SCAN domain containing 10
chr12_+_4918342 0.03 ENST00000280684.3
ENST00000433855.1
KCNA6
potassium voltage-gated channel, shaker-related subfamily, member 6
chr1_-_23520755 0.02 ENST00000314113.3
HTR1D
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr17_-_40169429 0.02 ENST00000316603.7
ENST00000588641.1
DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr21_+_44313375 0.02 ENST00000354250.2
ENST00000340344.4
NDUFV3
NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
chr11_+_64879317 0.02 ENST00000526809.1
ENST00000279263.7
ENST00000524986.1
ENST00000534371.1
ENST00000540748.1
ENST00000525385.1
ENST00000345348.5
ENST00000531321.1
ENST00000529414.1
ENST00000526085.1
ENST00000530750.1
TM7SF2
transmembrane 7 superfamily member 2
chr5_+_140810132 0.02 ENST00000252085.3
PCDHGA12
protocadherin gamma subfamily A, 12
chr17_+_38333263 0.02 ENST00000456989.2
ENST00000543876.1
ENST00000544503.1
ENST00000264644.6
ENST00000538884.1
RAPGEFL1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr7_-_27224795 0.02 ENST00000006015.3
HOXA11
homeobox A11
chr22_-_50524298 0.02 ENST00000311597.5
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr5_+_179105615 0.02 ENST00000514383.1
CANX
calnexin
chrX_+_40944871 0.02 ENST00000378308.2
ENST00000324545.8
USP9X
ubiquitin specific peptidase 9, X-linked
chr9_+_127020202 0.02 ENST00000373600.3
ENST00000320246.5
NEK6
NIMA-related kinase 6
chr15_+_42696954 0.02 ENST00000337571.4
ENST00000569136.1
CAPN3
calpain 3, (p94)
chr17_-_15244894 0.02 ENST00000338696.2
ENST00000543896.1
ENST00000539245.1
ENST00000539316.1
ENST00000395930.1
TEKT3
tektin 3
chr18_-_13915530 0.02 ENST00000327606.3
MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr11_-_111175739 0.02 ENST00000532918.1
COLCA1
colorectal cancer associated 1
chr20_-_41818373 0.02 ENST00000373187.1
ENST00000356100.2
ENST00000373184.1
ENST00000373190.1
PTPRT
protein tyrosine phosphatase, receptor type, T
chr5_+_75699040 0.02 ENST00000274364.6
IQGAP2
IQ motif containing GTPase activating protein 2
chr12_-_70004942 0.02 ENST00000361484.3
LRRC10
leucine rich repeat containing 10
chr14_+_64565442 0.02 ENST00000553308.1
SYNE2
spectrin repeat containing, nuclear envelope 2
chrX_-_13835398 0.02 ENST00000475307.1
GPM6B
glycoprotein M6B
chr19_+_14672755 0.02 ENST00000594545.1
TECR
trans-2,3-enoyl-CoA reductase
chr3_-_123710893 0.02 ENST00000467907.1
ENST00000459660.1
ENST00000495093.1
ENST00000460743.1
ENST00000405845.3
ENST00000484329.1
ENST00000479867.1
ENST00000496145.1
ROPN1
rhophilin associated tail protein 1
chrX_-_154299501 0.02 ENST00000369476.3
ENST00000369484.3
MTCP1
CMC4
mature T-cell proliferation 1
C-x(9)-C motif containing 4
chr11_+_17756279 0.02 ENST00000265969.6
KCNC1
potassium voltage-gated channel, Shaw-related subfamily, member 1
chr4_+_144354644 0.02 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr17_+_53343171 0.02 ENST00000430986.2
HLF
hepatic leukemia factor
chr17_+_66521936 0.02 ENST00000592800.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr5_-_88180342 0.02 ENST00000502983.1
MEF2C
myocyte enhancer factor 2C
chr2_-_180610767 0.02 ENST00000409343.1
ZNF385B
zinc finger protein 385B
chr22_-_50523760 0.02 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr1_-_207143802 0.02 ENST00000324852.4
ENST00000400962.3
FCAMR
Fc receptor, IgA, IgM, high affinity
chr2_-_27545431 0.02 ENST00000233545.2
MPV17
MpV17 mitochondrial inner membrane protein
chr2_-_85895295 0.02 ENST00000428225.1
ENST00000519937.2
SFTPB
surfactant protein B
chrY_+_16634483 0.02 ENST00000382872.1
NLGN4Y
neuroligin 4, Y-linked
chr16_-_3149229 0.02 ENST00000572431.1
ENST00000572548.1
ZSCAN10
zinc finger and SCAN domain containing 10
chr4_-_186682716 0.02 ENST00000445343.1
SORBS2
sorbin and SH3 domain containing 2
chr7_-_87342564 0.02 ENST00000265724.3
ENST00000416177.1
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr3_-_53164423 0.02 ENST00000467048.1
ENST00000394738.3
ENST00000296292.3
RFT1
RFT1 homolog (S. cerevisiae)
chr14_+_94393605 0.02 ENST00000556222.1
ENST00000554404.1
ENST00000557000.2
FAM181A
family with sequence similarity 181, member A
chr19_+_16999654 0.02 ENST00000248076.3
F2RL3
coagulation factor II (thrombin) receptor-like 3
chr3_-_111314230 0.02 ENST00000317012.4
ZBED2
zinc finger, BED-type containing 2
chr3_+_23847394 0.02 ENST00000306627.3
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr15_+_74421961 0.02 ENST00000565159.1
ENST00000567206.1
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr13_-_95364389 0.02 ENST00000376945.2
SOX21
SRY (sex determining region Y)-box 21
chr1_+_207494853 0.02 ENST00000367064.3
ENST00000367063.2
ENST00000391921.4
ENST00000367067.4
ENST00000314754.8
ENST00000367065.5
ENST00000391920.4
ENST00000367062.4
ENST00000343420.6
CD55
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
chr8_+_76452097 0.02 ENST00000396423.2
HNF4G
hepatocyte nuclear factor 4, gamma
chr17_+_54230819 0.01 ENST00000318698.2
ENST00000566473.2
ANKFN1
ankyrin-repeat and fibronectin type III domain containing 1
chrX_+_71353499 0.01 ENST00000373677.1
NHSL2
NHS-like 2
chr17_+_48624450 0.01 ENST00000006658.6
ENST00000356488.4
ENST00000393244.3
SPATA20
spermatogenesis associated 20
chr9_+_116263639 0.01 ENST00000343817.5
RGS3
regulator of G-protein signaling 3
chr3_+_124223586 0.01 ENST00000393496.1
KALRN
kalirin, RhoGEF kinase
chr1_+_100817262 0.01 ENST00000455467.1
CDC14A
cell division cycle 14A
chr21_+_17791838 0.01 ENST00000453910.1
LINC00478
long intergenic non-protein coding RNA 478
chr19_-_5680499 0.01 ENST00000587589.1
C19orf70
chromosome 19 open reading frame 70
chr9_+_134065519 0.01 ENST00000531600.1
NUP214
nucleoporin 214kDa
chr7_-_37488777 0.01 ENST00000445322.1
ENST00000448602.1
ELMO1
engulfment and cell motility 1
chr18_+_42277095 0.01 ENST00000591940.1
SETBP1
SET binding protein 1
chr3_+_46283916 0.01 ENST00000395940.2
CCR3
chemokine (C-C motif) receptor 3
chr6_+_33378738 0.01 ENST00000374512.3
ENST00000374516.3
PHF1
PHD finger protein 1
chr7_-_27224842 0.01 ENST00000517402.1
HOXA11
homeobox A11
chr15_+_42841008 0.01 ENST00000260372.3
ENST00000568876.1
ENST00000568846.2
ENST00000562398.1
HAUS2
HAUS augmin-like complex, subunit 2
chr1_+_76540386 0.01 ENST00000328299.3
ST6GALNAC3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr12_+_93772402 0.01 ENST00000546925.1
NUDT4
nudix (nucleoside diphosphate linked moiety X)-type motif 4
chr7_-_28220354 0.01 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr15_-_72563585 0.01 ENST00000287196.9
ENST00000260376.7
PARP6
poly (ADP-ribose) polymerase family, member 6
chr9_+_134065506 0.01 ENST00000483497.2
NUP214
nucleoporin 214kDa
chr10_-_101841588 0.01 ENST00000370418.3
CPN1
carboxypeptidase N, polypeptide 1
chr6_-_112115074 0.01 ENST00000368667.2
FYN
FYN oncogene related to SRC, FGR, YES
chr17_+_58755184 0.01 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3
breast carcinoma amplified sequence 3
chr17_+_75447326 0.01 ENST00000591088.1
SEPT9
septin 9
chr15_+_78799895 0.01 ENST00000408962.2
ENST00000388988.4
ENST00000360519.3
HYKK
hydroxylysine kinase
chr12_-_53298841 0.01 ENST00000293308.6
KRT8
keratin 8
chr10_+_75504105 0.01 ENST00000535742.1
ENST00000546025.1
ENST00000345254.4
ENST00000540668.1
ENST00000339365.2
ENST00000411652.2
SEC24C
SEC24 family member C
chrX_+_115567767 0.01 ENST00000371900.4
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr17_-_7493390 0.01 ENST00000538513.2
ENST00000570788.1
ENST00000250055.2
SOX15
SRY (sex determining region Y)-box 15
chr19_-_14945933 0.01 ENST00000322301.3
OR7A5
olfactory receptor, family 7, subfamily A, member 5
chr3_-_39234074 0.01 ENST00000340369.3
ENST00000421646.1
ENST00000396251.1
XIRP1
xin actin-binding repeat containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:2000656 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.0 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.2 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.0 0.1 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.1 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.1 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.0 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0061528 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.0 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.0 GO:0052418 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.0 GO:0006579 amino-acid betaine catabolic process(GO:0006579)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0015322 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.0 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID S1P S1P4 PATHWAY S1P4 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.1 REACTOME OPSINS Genes involved in Opsins