Project

NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for NKX2-2

Z-value: 0.54

Motif logo

logo of

Transcription factors associated with NKX2-2

Gene Symbol Gene ID Gene Info
NKX2-2
ENSG00000125820.5 NK2 homeobox 2

Activity profile of NKX2-2 motif

Sorted Z-values of NKX2-2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_37723336 1.42 ENST00000450180.1
GPR141
G protein-coupled receptor 141
chr12_+_78359999 0.73 ENST00000550503.1
NAV3
neuron navigator 3
chr17_+_38171681 0.69 ENST00000225474.2
ENST00000331769.2
ENST00000394148.3
ENST00000577675.1
CSF3
colony stimulating factor 3 (granulocyte)
chr17_-_38859996 0.60 ENST00000264651.2
KRT24
keratin 24
chr17_+_38171614 0.49 ENST00000583218.1
ENST00000394149.3
CSF3
colony stimulating factor 3 (granulocyte)
chr1_-_153363452 0.44 ENST00000368732.1
ENST00000368733.3
S100A8
S100 calcium binding protein A8
chrX_+_115567767 0.41 ENST00000371900.4
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr3_-_152058779 0.34 ENST00000408960.3
TMEM14E
transmembrane protein 14E
chr7_+_37723450 0.28 ENST00000447769.1
GPR141
G protein-coupled receptor 141
chr12_-_49582978 0.26 ENST00000301071.7
TUBA1A
tubulin, alpha 1a
chr3_+_142838091 0.22 ENST00000309575.3
CHST2
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
chr2_-_36779411 0.20 ENST00000406220.1
AC007401.2
Uncharacterized protein
chr19_-_44174330 0.19 ENST00000340093.3
PLAUR
plasminogen activator, urokinase receptor
chr2_+_152214098 0.19 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr1_+_32666188 0.18 ENST00000421922.2
CCDC28B
coiled-coil domain containing 28B
chr5_+_147582348 0.18 ENST00000514389.1
SPINK6
serine peptidase inhibitor, Kazal type 6
chr4_+_89299885 0.17 ENST00000380265.5
ENST00000273960.3
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr14_+_23654525 0.17 ENST00000399910.1
ENST00000492621.1
C14orf164
chromosome 14 open reading frame 164
chr4_-_76957214 0.17 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr3_-_121379739 0.16 ENST00000428394.2
ENST00000314583.3
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr19_-_44174305 0.16 ENST00000601723.1
ENST00000339082.3
PLAUR
plasminogen activator, urokinase receptor
chr14_+_21467414 0.16 ENST00000554422.1
ENST00000298681.4
SLC39A2
solute carrier family 39 (zinc transporter), member 2
chr19_-_51568324 0.15 ENST00000595547.1
ENST00000335422.3
ENST00000595793.1
ENST00000596955.1
KLK13
kallikrein-related peptidase 13
chr3_+_98482175 0.15 ENST00000485391.1
ENST00000492254.1
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr6_-_72129806 0.15 ENST00000413945.1
ENST00000602878.1
ENST00000436803.1
ENST00000421704.1
ENST00000441570.1
LINC00472
long intergenic non-protein coding RNA 472
chr21_+_30968360 0.15 ENST00000333765.4
GRIK1-AS2
GRIK1 antisense RNA 2
chr5_+_167718604 0.15 ENST00000265293.4
WWC1
WW and C2 domain containing 1
chr1_-_26633480 0.14 ENST00000450041.1
UBXN11
UBX domain protein 11
chr5_+_148206156 0.14 ENST00000305988.4
ADRB2
adrenoceptor beta 2, surface
chr19_-_17366257 0.14 ENST00000594059.1
AC010646.3
Uncharacterized protein
chr3_-_114790179 0.14 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr2_-_70409953 0.14 ENST00000419381.1
C2orf42
chromosome 2 open reading frame 42
chr8_-_95220775 0.13 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr5_-_66942617 0.13 ENST00000507298.1
RP11-83M16.5
RP11-83M16.5
chr8_-_133772870 0.12 ENST00000522334.1
ENST00000519016.1
TMEM71
transmembrane protein 71
chr9_+_99690592 0.12 ENST00000354649.3
NUTM2G
NUT family member 2G
chr11_-_7698453 0.12 ENST00000524608.1
CYB5R2
cytochrome b5 reductase 2
chr17_+_61086917 0.12 ENST00000424789.2
ENST00000389520.4
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr5_+_159656437 0.12 ENST00000402432.3
FABP6
fatty acid binding protein 6, ileal
chr14_+_39703112 0.11 ENST00000555143.1
ENST00000280082.3
MIA2
melanoma inhibitory activity 2
chrY_+_15418467 0.11 ENST00000595988.1
AC010877.1
Uncharacterized protein
chr2_-_214015111 0.11 ENST00000433134.1
IKZF2
IKAROS family zinc finger 2 (Helios)
chr1_+_15272271 0.11 ENST00000400797.3
KAZN
kazrin, periplakin interacting protein
chr17_+_18647326 0.11 ENST00000395667.1
ENST00000395665.4
ENST00000308799.4
ENST00000301938.4
FBXW10
F-box and WD repeat domain containing 10
chr12_+_76653682 0.11 ENST00000553247.1
RP11-54A9.1
RP11-54A9.1
chr15_-_60683326 0.11 ENST00000559350.1
ENST00000558986.1
ENST00000560389.1
ANXA2
annexin A2
chr22_-_42086477 0.10 ENST00000402458.1
NHP2L1
NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
chr19_-_39881669 0.10 ENST00000221266.7
PAF1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chrX_-_19817869 0.10 ENST00000379698.4
SH3KBP1
SH3-domain kinase binding protein 1
chr6_+_151561085 0.10 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr11_+_93479588 0.10 ENST00000526335.1
C11orf54
chromosome 11 open reading frame 54
chr18_-_68004529 0.10 ENST00000578633.1
RP11-484N16.1
RP11-484N16.1
chrX_-_130037162 0.10 ENST00000432489.1
ENOX2
ecto-NOX disulfide-thiol exchanger 2
chr4_-_178169927 0.09 ENST00000512516.1
RP11-487E13.1
Uncharacterized protein
chr8_+_11666649 0.09 ENST00000528643.1
ENST00000525777.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr8_-_133772794 0.09 ENST00000519187.1
ENST00000523829.1
ENST00000356838.3
ENST00000377901.4
ENST00000519304.1
TMEM71
transmembrane protein 71
chr10_+_32735030 0.09 ENST00000277657.6
ENST00000362006.5
CCDC7
coiled-coil domain containing 7
chr5_-_78281603 0.09 ENST00000264914.4
ARSB
arylsulfatase B
chr10_-_36812323 0.09 ENST00000543053.1
NAMPTL
nicotinamide phosphoribosyltransferase-like
chr11_-_26743546 0.09 ENST00000280467.6
ENST00000396005.3
SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr8_+_11660227 0.09 ENST00000443614.2
ENST00000525900.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr9_-_85882145 0.09 ENST00000328788.1
FRMD3
FERM domain containing 3
chr17_+_7591639 0.09 ENST00000396463.2
WRAP53
WD repeat containing, antisense to TP53
chr4_-_54518619 0.09 ENST00000507168.1
ENST00000510143.1
LNX1
ligand of numb-protein X 1, E3 ubiquitin protein ligase
chr10_-_112678692 0.09 ENST00000605742.1
BBIP1
BBSome interacting protein 1
chr2_-_203735484 0.09 ENST00000420558.1
ENST00000418208.1
ICA1L
islet cell autoantigen 1,69kDa-like
chr3_-_57326704 0.08 ENST00000487349.1
ENST00000389601.3
ASB14
ankyrin repeat and SOCS box containing 14
chr14_-_38036271 0.08 ENST00000556024.1
RP11-356O9.2
RP11-356O9.2
chr4_-_105416039 0.08 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr2_-_151905288 0.08 ENST00000409243.1
AC023469.1
HCG1817310; Uncharacterized protein
chr3_+_108541545 0.08 ENST00000295756.6
TRAT1
T cell receptor associated transmembrane adaptor 1
chr14_+_94547675 0.08 ENST00000393115.3
ENST00000554166.1
ENST00000556381.1
ENST00000553664.1
ENST00000555341.1
ENST00000557218.1
ENST00000554544.1
ENST00000557066.1
IFI27L1
interferon, alpha-inducible protein 27-like 1
chr10_-_121296045 0.08 ENST00000392865.1
RGS10
regulator of G-protein signaling 10
chr2_+_219110149 0.08 ENST00000456575.1
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr19_-_18433910 0.08 ENST00000594828.3
ENST00000593829.1
LSM4
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr1_+_48569306 0.08 ENST00000601108.1
AL109659.1
HCG1780467; PRO0529; Uncharacterized protein
chr14_-_38028689 0.08 ENST00000553425.1
RP11-356O9.2
RP11-356O9.2
chr7_-_7782204 0.08 ENST00000418534.2
AC007161.5
AC007161.5
chr3_+_167582561 0.08 ENST00000463642.1
ENST00000464514.1
RP11-298O21.6
RP11-298O21.7
RP11-298O21.6
RP11-298O21.7
chr7_+_2394445 0.08 ENST00000360876.4
ENST00000413917.1
ENST00000397011.2
EIF3B
eukaryotic translation initiation factor 3, subunit B
chr20_+_30102231 0.07 ENST00000335574.5
ENST00000340852.5
ENST00000398174.3
ENST00000376127.3
ENST00000344042.5
HM13
histocompatibility (minor) 13
chr18_+_55888767 0.07 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr10_-_36813162 0.07 ENST00000440465.1
NAMPTL
nicotinamide phosphoribosyltransferase-like
chr3_+_101280677 0.07 ENST00000309922.6
ENST00000495642.1
TRMT10C
tRNA methyltransferase 10 homolog C (S. cerevisiae)
chr19_+_39616410 0.07 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
PAK4
p21 protein (Cdc42/Rac)-activated kinase 4
chr16_-_1464688 0.07 ENST00000389221.4
ENST00000508903.2
ENST00000397462.1
ENST00000301712.5
UNKL
unkempt family zinc finger-like
chr22_-_43567750 0.07 ENST00000494035.1
TTLL12
tubulin tyrosine ligase-like family, member 12
chrX_-_153363125 0.07 ENST00000407218.1
ENST00000453960.2
MECP2
methyl CpG binding protein 2 (Rett syndrome)
chrX_-_130037198 0.07 ENST00000370935.1
ENST00000338144.3
ENST00000394363.1
ENOX2
ecto-NOX disulfide-thiol exchanger 2
chr15_-_60690163 0.07 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
ANXA2
annexin A2
chr7_-_944631 0.07 ENST00000453175.2
ADAP1
ArfGAP with dual PH domains 1
chr17_-_29624343 0.07 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr18_-_70931689 0.07 ENST00000581862.1
RP11-169F17.1
Protein LOC400655
chr12_-_28124903 0.07 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH
parathyroid hormone-like hormone
chr5_+_35852797 0.07 ENST00000508941.1
IL7R
interleukin 7 receptor
chr19_-_3971050 0.07 ENST00000545797.2
ENST00000596311.1
DAPK3
death-associated protein kinase 3
chr8_+_11660120 0.07 ENST00000220584.4
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr3_+_75713481 0.07 ENST00000308062.3
ENST00000464571.1
FRG2C
FSHD region gene 2 family, member C
chr1_-_161046266 0.07 ENST00000453926.2
PVRL4
poliovirus receptor-related 4
chrX_+_105066524 0.07 ENST00000243300.9
ENST00000428173.2
NRK
Nik related kinase
chr4_+_80584903 0.06 ENST00000506460.1
RP11-452C8.1
RP11-452C8.1
chr6_-_116833500 0.06 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr6_+_77484663 0.06 ENST00000607287.1
RP11-354K4.2
RP11-354K4.2
chr1_-_159880159 0.06 ENST00000599780.1
AL590560.1
HCG1995379; Uncharacterized protein
chr5_+_140552218 0.06 ENST00000231137.3
PCDHB7
protocadherin beta 7
chr1_-_198906528 0.06 ENST00000432296.1
MIR181A1HG
MIR181A1 host gene (non-protein coding)
chr11_-_64900791 0.06 ENST00000531018.1
SYVN1
synovial apoptosis inhibitor 1, synoviolin
chr1_-_45253377 0.06 ENST00000372207.3
BEST4
bestrophin 4
chr19_-_14889349 0.06 ENST00000315576.3
ENST00000392967.2
ENST00000346057.1
ENST00000353876.1
ENST00000353005.1
EMR2
egf-like module containing, mucin-like, hormone receptor-like 2
chr4_-_40477766 0.06 ENST00000507180.1
RBM47
RNA binding motif protein 47
chr17_+_7591747 0.06 ENST00000534050.1
WRAP53
WD repeat containing, antisense to TP53
chr8_-_99955042 0.06 ENST00000519420.1
STK3
serine/threonine kinase 3
chr5_-_150521192 0.06 ENST00000523714.1
ENST00000521749.1
ANXA6
annexin A6
chr6_-_113754604 0.06 ENST00000421737.1
RP1-124C6.1
RP1-124C6.1
chr14_-_24020858 0.06 ENST00000419474.3
ZFHX2
zinc finger homeobox 2
chr13_-_20357057 0.06 ENST00000338910.4
PSPC1
paraspeckle component 1
chr14_+_94547628 0.06 ENST00000555523.1
IFI27L1
interferon, alpha-inducible protein 27-like 1
chr5_+_147582387 0.06 ENST00000325630.2
SPINK6
serine peptidase inhibitor, Kazal type 6
chr3_-_33686743 0.05 ENST00000333778.6
ENST00000539981.1
CLASP2
cytoplasmic linker associated protein 2
chr13_+_111855399 0.05 ENST00000426768.2
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr10_+_90346519 0.05 ENST00000371939.3
LIPJ
lipase, family member J
chr18_+_32558380 0.05 ENST00000588349.2
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr1_-_41328018 0.05 ENST00000372638.2
CITED4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr21_-_19858196 0.05 ENST00000422787.1
TMPRSS15
transmembrane protease, serine 15
chr12_+_76653611 0.05 ENST00000550380.1
RP11-54A9.1
RP11-54A9.1
chr4_+_95376396 0.05 ENST00000508216.1
ENST00000514743.1
PDLIM5
PDZ and LIM domain 5
chr16_+_23194033 0.05 ENST00000300061.2
SCNN1G
sodium channel, non-voltage-gated 1, gamma subunit
chr7_+_16700806 0.05 ENST00000446596.1
ENST00000438834.1
BZW2
basic leucine zipper and W2 domains 2
chr19_+_49838653 0.05 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37
CD37 molecule
chr1_-_213188772 0.05 ENST00000544555.1
ANGEL2
angel homolog 2 (Drosophila)
chr13_+_25875662 0.05 ENST00000381736.3
ENST00000463407.1
ENST00000381718.3
NUPL1
nucleoporin like 1
chr10_+_81462983 0.05 ENST00000448135.1
ENST00000429828.1
ENST00000372321.1
NUTM2B
NUT family member 2B
chr9_+_103340354 0.05 ENST00000307584.5
MURC
muscle-related coiled-coil protein
chr15_+_56657613 0.05 ENST00000352903.2
ENST00000537232.1
ENST00000561221.2
ENST00000558083.2
TEX9
testis expressed 9
chr6_+_151561506 0.05 ENST00000253332.1
AKAP12
A kinase (PRKA) anchor protein 12
chr16_-_56223480 0.05 ENST00000565155.1
RP11-461O7.1
RP11-461O7.1
chr18_+_3466248 0.05 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
RP11-838N2.4
chr11_+_34654011 0.05 ENST00000531794.1
EHF
ets homologous factor
chr4_-_71532207 0.05 ENST00000543780.1
ENST00000391614.3
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr5_+_154181816 0.05 ENST00000518677.1
LARP1
La ribonucleoprotein domain family, member 1
chr1_+_84630352 0.05 ENST00000450730.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr3_-_33686925 0.05 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chr17_+_15604513 0.05 ENST00000481540.1
ZNF286A
Homo sapiens zinc finger protein 286A (ZNF286A), transcript variant 6, mRNA.
chr4_+_3076388 0.05 ENST00000355072.5
HTT
huntingtin
chr13_+_25875785 0.05 ENST00000381747.3
NUPL1
nucleoporin like 1
chr2_-_151344172 0.05 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr1_+_50459990 0.05 ENST00000448346.1
AL645730.2
AL645730.2
chr2_+_162272605 0.05 ENST00000389554.3
TBR1
T-box, brain, 1
chr18_-_43684230 0.05 ENST00000592989.1
ENST00000589869.1
ATP5A1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr18_+_72201829 0.04 ENST00000582365.1
CNDP1
carnosine dipeptidase 1 (metallopeptidase M20 family)
chr7_+_80253387 0.04 ENST00000438020.1
CD36
CD36 molecule (thrombospondin receptor)
chr12_+_116955659 0.04 ENST00000552992.1
RP11-148B3.1
RP11-148B3.1
chr1_+_61547894 0.04 ENST00000403491.3
NFIA
nuclear factor I/A
chr2_+_103035102 0.04 ENST00000264260.2
IL18RAP
interleukin 18 receptor accessory protein
chr4_-_119759795 0.04 ENST00000419654.2
SEC24D
SEC24 family member D
chr4_+_139230865 0.04 ENST00000502757.1
ENST00000507145.1
ENST00000515282.1
ENST00000510736.1
LINC00499
long intergenic non-protein coding RNA 499
chr9_-_98079965 0.04 ENST00000289081.3
FANCC
Fanconi anemia, complementation group C
chr8_-_102181718 0.04 ENST00000565617.1
KB-1460A1.5
KB-1460A1.5
chr2_+_102953608 0.04 ENST00000311734.2
ENST00000409584.1
IL1RL1
interleukin 1 receptor-like 1
chr21_+_17214724 0.04 ENST00000449491.1
USP25
ubiquitin specific peptidase 25
chr19_+_47634039 0.04 ENST00000597808.1
ENST00000413379.3
ENST00000600706.1
ENST00000540850.1
ENST00000598840.1
ENST00000600753.1
ENST00000270225.7
ENST00000392776.3
SAE1
SUMO1 activating enzyme subunit 1
chr9_-_10612703 0.04 ENST00000463477.1
PTPRD
protein tyrosine phosphatase, receptor type, D
chr10_-_61513146 0.04 ENST00000430431.1
LINC00948
long intergenic non-protein coding RNA 948
chr14_+_32963433 0.04 ENST00000554410.1
AKAP6
A kinase (PRKA) anchor protein 6
chr7_+_18548878 0.04 ENST00000456174.2
HDAC9
histone deacetylase 9
chr2_+_173724771 0.04 ENST00000538974.1
ENST00000540783.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr16_+_30212050 0.04 ENST00000563322.1
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr10_-_104262426 0.04 ENST00000487599.1
ACTR1A
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr2_-_160472052 0.04 ENST00000437839.1
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr10_+_81601114 0.04 ENST00000602967.1
ENST00000429984.3
NUTM2E
NUT family member 2E
chr4_-_140477928 0.04 ENST00000274031.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr1_-_98515395 0.04 ENST00000424528.2
MIR137HG
MIR137 host gene (non-protein coding)
chr2_+_113299990 0.04 ENST00000537335.1
ENST00000417433.2
POLR1B
polymerase (RNA) I polypeptide B, 128kDa
chr4_+_74269956 0.04 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
ALB
albumin
chr5_-_139937895 0.04 ENST00000336283.6
SRA1
steroid receptor RNA activator 1
chr10_-_104262460 0.04 ENST00000446605.2
ENST00000369905.4
ENST00000545684.1
ACTR1A
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr15_-_56209306 0.04 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
NEDD4
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr7_+_2393714 0.04 ENST00000431643.1
EIF3B
eukaryotic translation initiation factor 3, subunit B
chr11_-_8892900 0.04 ENST00000526155.1
ENST00000524757.1
ENST00000527392.1
ENST00000534665.1
ENST00000525169.1
ENST00000527516.1
ENST00000533471.1
ST5
suppression of tumorigenicity 5
chr3_+_189507523 0.04 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
TP63
tumor protein p63
chr16_+_10837643 0.04 ENST00000574334.1
ENST00000283027.5
ENST00000433392.2
NUBP1
nucleotide binding protein 1
chr1_-_202936394 0.04 ENST00000367249.4
CYB5R1
cytochrome b5 reductase 1
chr14_+_56584414 0.04 ENST00000559044.1
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr17_+_56833184 0.03 ENST00000308249.2
PPM1E
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr9_-_139361503 0.03 ENST00000453963.1
SEC16A
SEC16 homolog A (S. cerevisiae)
chr6_+_1080164 0.03 ENST00000314040.1
AL033381.1
Uncharacterized protein; cDNA FLJ34594 fis, clone KIDNE2009109
chr5_+_156887027 0.03 ENST00000435489.2
ENST00000311946.7
NIPAL4
NIPA-like domain containing 4
chrX_-_15333736 0.03 ENST00000380470.3
ASB11
ankyrin repeat and SOCS box containing 11
chrX_+_36053908 0.03 ENST00000378660.2
CHDC2
calponin homology domain containing 2
chr12_+_101869096 0.03 ENST00000551346.1
SPIC
Spi-C transcription factor (Spi-1/PU.1 related)
chr3_+_41241596 0.03 ENST00000450969.1
CTNNB1
catenin (cadherin-associated protein), beta 1, 88kDa
chr12_+_109826524 0.03 ENST00000431443.2
MYO1H
myosin IH
chr7_-_92855762 0.03 ENST00000453812.2
ENST00000394468.2
HEPACAM2
HEPACAM family member 2
chr5_+_118812294 0.03 ENST00000509514.1
HSD17B4
hydroxysteroid (17-beta) dehydrogenase 4
chr3_+_38206975 0.03 ENST00000446845.1
ENST00000311806.3
OXSR1
oxidative stress responsive 1
chr7_+_150065278 0.03 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
REPIN1
replication initiator 1
chr16_+_30212378 0.03 ENST00000569485.1
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr20_+_56964169 0.03 ENST00000475243.1
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr10_+_89420706 0.03 ENST00000427144.2
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr2_-_24270217 0.03 ENST00000295148.4
ENST00000406895.3
C2orf44
chromosome 2 open reading frame 44

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.2 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.4 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.2 GO:0044145 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.5 GO:0032119 sequestering of zinc ion(GO:0032119)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.1 GO:0060723 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.0 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 0.1 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.0 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.0 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.0 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.4 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.8 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.4 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0015322 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.0 0.1 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.0 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.0 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.0 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.0 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.0 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis