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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NFIA

Z-value: 0.98

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Transcription factors associated with NFIA

Gene Symbol Gene ID Gene Info
NFIA
ENSG00000162599.11 nuclear factor I A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFIAhg19_v2_chr1_+_61548225_61548299-0.582.3e-01Click!

Activity profile of NFIA motif

Sorted Z-values of NFIA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_17598506 1.19 ENST00000451792.1
AC017060.1
AC017060.1
chr7_-_41742697 0.89 ENST00000242208.4
INHBA
inhibin, beta A
chr11_+_64004888 0.58 ENST00000541681.1
VEGFB
vascular endothelial growth factor B
chr12_-_15038779 0.53 ENST00000228938.5
ENST00000539261.1
MGP
matrix Gla protein
chr2_-_214017151 0.52 ENST00000452786.1
IKZF2
IKAROS family zinc finger 2 (Helios)
chr15_-_79576156 0.47 ENST00000560452.1
ENST00000560872.1
ENST00000560732.1
ENST00000559979.1
ENST00000560533.1
ENST00000559225.1
RP11-17L5.4
RP11-17L5.4
chr2_+_173955327 0.46 ENST00000422149.1
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr14_+_77582905 0.44 ENST00000557408.1
TMEM63C
transmembrane protein 63C
chr9_+_108424738 0.41 ENST00000334077.3
TAL2
T-cell acute lymphocytic leukemia 2
chr12_-_53207842 0.39 ENST00000458244.2
KRT4
keratin 4
chrX_-_133792480 0.36 ENST00000359237.4
PLAC1
placenta-specific 1
chr8_+_40010989 0.35 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chr2_-_31637560 0.34 ENST00000379416.3
XDH
xanthine dehydrogenase
chr17_+_65375082 0.34 ENST00000584471.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr1_+_41447609 0.32 ENST00000543104.1
CTPS1
CTP synthase 1
chr7_-_21985489 0.30 ENST00000356195.5
ENST00000447180.1
ENST00000373934.4
ENST00000457951.1
CDCA7L
cell division cycle associated 7-like
chr21_-_28215332 0.29 ENST00000517777.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr17_+_1733251 0.29 ENST00000570451.1
RPA1
replication protein A1, 70kDa
chr17_-_47786375 0.28 ENST00000511657.1
SLC35B1
solute carrier family 35, member B1
chr5_-_137374288 0.27 ENST00000514310.1
FAM13B
family with sequence similarity 13, member B
chr10_-_106240032 0.26 ENST00000447860.1
RP11-127O4.3
RP11-127O4.3
chr4_-_87770416 0.26 ENST00000273905.6
SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter), member 6
chr15_+_36994210 0.25 ENST00000562489.1
C15orf41
chromosome 15 open reading frame 41
chr7_-_151330218 0.25 ENST00000476632.1
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr6_+_43968306 0.24 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223
chromosome 6 open reading frame 223
chr17_-_15168624 0.24 ENST00000312280.3
ENST00000494511.1
ENST00000580584.1
PMP22
peripheral myelin protein 22
chr5_-_55008136 0.24 ENST00000503891.1
ENST00000507109.1
SLC38A9
solute carrier family 38, member 9
chr3_+_109128961 0.23 ENST00000489670.1
RP11-702L6.4
RP11-702L6.4
chr3_+_111718173 0.23 ENST00000494932.1
TAGLN3
transgelin 3
chr14_-_98444386 0.23 ENST00000556462.1
ENST00000556138.1
C14orf64
chromosome 14 open reading frame 64
chr3_+_142342240 0.23 ENST00000497199.1
PLS1
plastin 1
chr1_+_209878182 0.22 ENST00000367027.3
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr3_-_155011483 0.22 ENST00000489090.1
RP11-451G4.2
RP11-451G4.2
chr1_-_204119009 0.22 ENST00000444817.1
ETNK2
ethanolamine kinase 2
chr16_+_82090028 0.22 ENST00000568090.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr3_-_93747425 0.21 ENST00000315099.2
STX19
syntaxin 19
chr7_-_7782204 0.20 ENST00000418534.2
AC007161.5
AC007161.5
chr3_+_172361483 0.20 ENST00000598405.1
AC007919.2
HCG1787166; PRO1163; Uncharacterized protein
chr9_-_5437818 0.20 ENST00000223864.2
PLGRKT
plasminogen receptor, C-terminal lysine transmembrane protein
chr11_-_122931881 0.20 ENST00000526110.1
ENST00000227378.3
HSPA8
heat shock 70kDa protein 8
chr6_-_113754604 0.20 ENST00000421737.1
RP1-124C6.1
RP1-124C6.1
chr2_-_113542063 0.19 ENST00000263339.3
IL1A
interleukin 1, alpha
chr2_-_61244550 0.19 ENST00000421319.1
PUS10
pseudouridylate synthase 10
chr5_+_53751445 0.19 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr11_-_128392085 0.19 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr1_-_205912577 0.19 ENST00000367135.3
ENST00000367134.2
SLC26A9
solute carrier family 26 (anion exchanger), member 9
chr16_-_55866997 0.19 ENST00000360526.3
ENST00000361503.4
CES1
carboxylesterase 1
chr2_+_152214098 0.18 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr2_+_54684327 0.18 ENST00000389980.3
SPTBN1
spectrin, beta, non-erythrocytic 1
chr8_+_86851932 0.18 ENST00000517368.1
CTA-392E5.1
CTA-392E5.1
chr21_-_35340759 0.18 ENST00000607953.1
AP000569.9
AP000569.9
chr17_+_7461580 0.18 ENST00000483039.1
ENST00000396542.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr4_+_153021899 0.18 ENST00000509332.1
ENST00000504144.1
ENST00000499452.2
RP11-18H21.1
RP11-18H21.1
chr16_-_19725899 0.18 ENST00000567367.1
KNOP1
lysine-rich nucleolar protein 1
chr11_+_126262027 0.18 ENST00000526311.1
ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr8_+_32579321 0.18 ENST00000522402.1
NRG1
neuregulin 1
chr8_+_32579271 0.17 ENST00000518084.1
NRG1
neuregulin 1
chr4_-_48271802 0.17 ENST00000381501.3
TEC
tec protein tyrosine kinase
chr7_-_99381798 0.17 ENST00000415003.1
ENST00000354593.2
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4
chr10_+_102821551 0.17 ENST00000370200.5
KAZALD1
Kazal-type serine peptidase inhibitor domain 1
chr2_+_234545148 0.17 ENST00000373445.1
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr1_-_41950342 0.17 ENST00000372587.4
EDN2
endothelin 2
chr12_+_82752275 0.17 ENST00000248306.3
METTL25
methyltransferase like 25
chr1_+_112016414 0.17 ENST00000343534.5
ENST00000369718.3
C1orf162
chromosome 1 open reading frame 162
chr1_+_95975672 0.17 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1
RP11-286B14.1
chr3_-_52488048 0.17 ENST00000232975.3
TNNC1
troponin C type 1 (slow)
chr15_+_41549105 0.17 ENST00000560965.1
CHP1
calcineurin-like EF-hand protein 1
chr7_+_129015484 0.16 ENST00000490911.1
AHCYL2
adenosylhomocysteinase-like 2
chr13_+_78109804 0.16 ENST00000535157.1
SCEL
sciellin
chr4_+_169633310 0.16 ENST00000510998.1
PALLD
palladin, cytoskeletal associated protein
chr11_+_34654011 0.16 ENST00000531794.1
EHF
ets homologous factor
chr16_-_55867146 0.16 ENST00000422046.2
CES1
carboxylesterase 1
chr1_-_243417762 0.16 ENST00000522191.1
CEP170
centrosomal protein 170kDa
chr22_+_25615489 0.16 ENST00000398215.2
CRYBB2
crystallin, beta B2
chr16_-_74455290 0.16 ENST00000339953.5
CLEC18B
C-type lectin domain family 18, member B
chr16_+_67840986 0.16 ENST00000561639.1
ENST00000567852.1
ENST00000565148.1
ENST00000388833.3
ENST00000561654.1
ENST00000431934.2
TSNAXIP1
translin-associated factor X interacting protein 1
chr2_+_33701684 0.16 ENST00000442390.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr4_-_157892167 0.16 ENST00000541126.1
PDGFC
platelet derived growth factor C
chr20_+_43343476 0.16 ENST00000372868.2
WISP2
WNT1 inducible signaling pathway protein 2
chr3_-_123168551 0.16 ENST00000462833.1
ADCY5
adenylate cyclase 5
chr13_-_46425865 0.16 ENST00000400405.2
SIAH3
siah E3 ubiquitin protein ligase family member 3
chr2_-_200320768 0.15 ENST00000428695.1
SATB2
SATB homeobox 2
chr5_-_43313574 0.15 ENST00000325110.6
ENST00000433297.2
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr19_+_13988061 0.15 ENST00000339133.5
ENST00000397555.2
NANOS3
nanos homolog 3 (Drosophila)
chrX_-_71497077 0.15 ENST00000373626.3
RPS4X
ribosomal protein S4, X-linked
chr4_+_146402346 0.15 ENST00000514778.1
ENST00000507594.1
SMAD1
SMAD family member 1
chr16_+_70207686 0.15 ENST00000541793.2
ENST00000314151.8
ENST00000565806.1
ENST00000569347.2
ENST00000536907.2
CLEC18C
C-type lectin domain family 18, member C
chr18_+_55712915 0.15 ENST00000592846.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr2_-_231989808 0.15 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr9_+_5890802 0.15 ENST00000381477.3
ENST00000381476.1
ENST00000381471.1
MLANA
melan-A
chrX_-_71497148 0.15 ENST00000316084.6
RPS4X
ribosomal protein S4, X-linked
chr9_+_84304628 0.15 ENST00000437181.1
RP11-154D17.1
RP11-154D17.1
chr2_-_136288740 0.14 ENST00000264159.6
ENST00000536680.1
ZRANB3
zinc finger, RAN-binding domain containing 3
chr20_+_43343886 0.14 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr3_+_4535155 0.14 ENST00000544951.1
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr3_+_190105909 0.14 ENST00000456423.1
CLDN16
claudin 16
chr16_+_15737124 0.14 ENST00000396355.1
ENST00000396353.2
NDE1
nudE neurodevelopment protein 1
chr11_+_15136462 0.14 ENST00000379556.3
ENST00000424273.1
INSC
inscuteable homolog (Drosophila)
chr17_+_9745786 0.14 ENST00000304773.5
GLP2R
glucagon-like peptide 2 receptor
chr16_-_89119355 0.14 ENST00000537498.1
CTD-2555A7.2
CTD-2555A7.2
chr6_-_2971494 0.13 ENST00000380539.1
SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr5_-_64777733 0.13 ENST00000381055.3
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr2_-_74645669 0.13 ENST00000518401.1
C2orf81
chromosome 2 open reading frame 81
chr5_-_168006324 0.13 ENST00000522176.1
PANK3
pantothenate kinase 3
chr17_-_39459103 0.13 ENST00000391353.1
KRTAP29-1
keratin associated protein 29-1
chr2_+_179184955 0.13 ENST00000315022.2
OSBPL6
oxysterol binding protein-like 6
chr8_+_55471630 0.13 ENST00000522001.1
RP11-53M11.3
RP11-53M11.3
chr1_-_154164534 0.13 ENST00000271850.7
ENST00000368530.2
TPM3
tropomyosin 3
chr2_+_159651821 0.13 ENST00000309950.3
ENST00000409042.1
DAPL1
death associated protein-like 1
chr9_+_130911770 0.13 ENST00000372998.1
LCN2
lipocalin 2
chr19_+_42254885 0.13 ENST00000595740.1
CEACAM6
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
chr14_-_69350920 0.13 ENST00000553290.1
ACTN1
actinin, alpha 1
chr11_+_111749650 0.13 ENST00000528125.1
C11orf1
chromosome 11 open reading frame 1
chr21_+_19617140 0.13 ENST00000299295.2
ENST00000338326.3
CHODL
chondrolectin
chr3_+_150264458 0.13 ENST00000487799.1
ENST00000460851.1
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr8_+_66619277 0.12 ENST00000521247.2
ENST00000527155.1
MTFR1
mitochondrial fission regulator 1
chr16_-_65106110 0.12 ENST00000562882.1
ENST00000567934.1
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr3_+_152017924 0.12 ENST00000465907.2
ENST00000492948.1
ENST00000485509.1
ENST00000464596.1
MBNL1
muscleblind-like splicing regulator 1
chr10_-_126138622 0.12 ENST00000451024.3
NKX1-2
NK1 homeobox 2
chr14_+_70234642 0.12 ENST00000555349.1
ENST00000554021.1
SRSF5
serine/arginine-rich splicing factor 5
chr5_+_132208014 0.12 ENST00000296877.2
LEAP2
liver expressed antimicrobial peptide 2
chr17_+_7462031 0.12 ENST00000380535.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr4_-_101439242 0.12 ENST00000296420.4
EMCN
endomucin
chr21_+_44394742 0.12 ENST00000432907.2
PKNOX1
PBX/knotted 1 homeobox 1
chr3_-_33260283 0.12 ENST00000412539.1
SUSD5
sushi domain containing 5
chr2_-_111291587 0.12 ENST00000437167.1
RGPD6
RANBP2-like and GRIP domain containing 6
chr2_-_227050079 0.12 ENST00000423838.1
AC068138.1
AC068138.1
chr4_+_71108300 0.12 ENST00000304954.3
CSN3
casein kappa
chr11_+_3875757 0.12 ENST00000525403.1
STIM1
stromal interaction molecule 1
chr2_+_135596180 0.12 ENST00000283054.4
ENST00000392928.1
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr3_+_72937182 0.12 ENST00000389617.4
GXYLT2
glucoside xylosyltransferase 2
chr5_-_111093759 0.12 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
NREP
neuronal regeneration related protein
chr9_-_127710292 0.12 ENST00000421514.1
GOLGA1
golgin A1
chr6_+_42989344 0.12 ENST00000244496.5
RRP36
ribosomal RNA processing 36 homolog (S. cerevisiae)
chr17_+_19314505 0.12 ENST00000461366.1
RNF112
ring finger protein 112
chr3_+_150264555 0.12 ENST00000406576.3
ENST00000482093.1
ENST00000273435.5
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr14_-_98444438 0.12 ENST00000512901.2
C14orf64
chromosome 14 open reading frame 64
chr8_+_101349823 0.11 ENST00000519566.1
KB-1991G8.1
KB-1991G8.1
chr3_+_10312604 0.11 ENST00000426850.1
TATDN2
TatD DNase domain containing 2
chr11_-_45928830 0.11 ENST00000449465.1
C11orf94
chromosome 11 open reading frame 94
chr3_-_131736593 0.11 ENST00000514999.1
CPNE4
copine IV
chr1_+_107683436 0.11 ENST00000370068.1
NTNG1
netrin G1
chr8_-_121824374 0.11 ENST00000517992.1
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr6_-_133079022 0.11 ENST00000525289.1
ENST00000326499.6
VNN2
vanin 2
chr12_+_57828521 0.11 ENST00000309668.2
INHBC
inhibin, beta C
chr5_+_36608280 0.11 ENST00000513646.1
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr8_+_9009296 0.11 ENST00000521718.1
RP11-10A14.4
Uncharacterized protein
chr12_+_56325231 0.11 ENST00000549368.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr19_-_13710678 0.11 ENST00000592864.1
CACNA1A
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr1_-_144364246 0.11 ENST00000540273.1
PPIAL4B
peptidylprolyl isomerase A (cyclophilin A)-like 4B
chr1_+_149553003 0.11 ENST00000369222.3
PPIAL4C
peptidylprolyl isomerase A (cyclophilin A)-like 4C
chrX_-_106146547 0.11 ENST00000276173.4
ENST00000411805.1
RIPPLY1
ripply transcriptional repressor 1
chr5_-_43313269 0.10 ENST00000511774.1
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr11_-_61101247 0.10 ENST00000543627.1
DDB1
damage-specific DNA binding protein 1, 127kDa
chr14_-_75083313 0.10 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2
CTD-2207P18.2
chr6_+_30951487 0.10 ENST00000486149.2
ENST00000376296.3
MUC21
mucin 21, cell surface associated
chr17_+_1733276 0.10 ENST00000254719.5
RPA1
replication protein A1, 70kDa
chr1_+_68150744 0.10 ENST00000370986.4
ENST00000370985.3
GADD45A
growth arrest and DNA-damage-inducible, alpha
chr4_-_114900831 0.10 ENST00000315366.7
ARSJ
arylsulfatase family, member J
chr11_-_65625678 0.10 ENST00000308162.5
CFL1
cofilin 1 (non-muscle)
chr2_+_102953608 0.10 ENST00000311734.2
ENST00000409584.1
IL1RL1
interleukin 1 receptor-like 1
chr11_+_28724129 0.10 ENST00000513853.1
RP11-115J23.1
RP11-115J23.1
chr3_+_159570722 0.10 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr3_+_32737027 0.10 ENST00000454516.2
CNOT10
CCR4-NOT transcription complex, subunit 10
chr2_-_242211359 0.10 ENST00000444092.1
HDLBP
high density lipoprotein binding protein
chr15_+_48051920 0.10 ENST00000559196.1
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr13_+_102104952 0.10 ENST00000376180.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr7_-_154863264 0.10 ENST00000395731.2
ENST00000543018.1
HTR5A-AS1
HTR5A antisense RNA 1
chr8_+_32579341 0.10 ENST00000519240.1
ENST00000539990.1
NRG1
neuregulin 1
chr11_-_85397167 0.10 ENST00000316398.3
CCDC89
coiled-coil domain containing 89
chr12_+_6977323 0.10 ENST00000462761.1
TPI1
triosephosphate isomerase 1
chrX_-_19817869 0.10 ENST00000379698.4
SH3KBP1
SH3-domain kinase binding protein 1
chr11_-_111649015 0.10 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr20_+_43029911 0.10 ENST00000443598.2
ENST00000316099.4
ENST00000415691.2
HNF4A
hepatocyte nuclear factor 4, alpha
chr9_+_117085336 0.10 ENST00000259396.8
ENST00000538816.1
ORM1
orosomucoid 1
chr11_-_13461790 0.10 ENST00000530907.1
BTBD10
BTB (POZ) domain containing 10
chr12_-_95510743 0.10 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr1_+_214163033 0.10 ENST00000607425.1
PROX1
prospero homeobox 1
chr10_-_101190202 0.10 ENST00000543866.1
ENST00000370508.5
GOT1
glutamic-oxaloacetic transaminase 1, soluble
chr1_+_110546700 0.10 ENST00000359172.3
ENST00000393614.4
AHCYL1
adenosylhomocysteinase-like 1
chr5_+_36606992 0.10 ENST00000505202.1
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr11_-_118023594 0.10 ENST00000529878.1
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
chrX_-_138287168 0.10 ENST00000436198.1
FGF13
fibroblast growth factor 13
chr8_+_124194875 0.10 ENST00000522648.1
ENST00000276699.6
FAM83A
family with sequence similarity 83, member A
chr5_-_115890554 0.10 ENST00000509665.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr7_+_35756066 0.10 ENST00000449644.1
AC018647.3
AC018647.3
chr7_+_114055052 0.09 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2
forkhead box P2
chr15_+_67458357 0.09 ENST00000537194.2
SMAD3
SMAD family member 3
chr1_-_160253998 0.09 ENST00000392220.2
PEX19
peroxisomal biogenesis factor 19
chr1_-_237167718 0.09 ENST00000464121.2
MT1HL1
metallothionein 1H-like 1
chrX_-_100604184 0.09 ENST00000372902.3
TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr8_-_116504448 0.09 ENST00000518018.1
TRPS1
trichorhinophalangeal syndrome I
chr22_-_42086477 0.09 ENST00000402458.1
NHP2L1
NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
chr1_-_21978312 0.09 ENST00000359708.4
ENST00000290101.4
RAP1GAP
RAP1 GTPase activating protein
chr2_-_65659762 0.09 ENST00000440972.1
SPRED2
sprouty-related, EVH1 domain containing 2
chr11_+_62556596 0.09 ENST00000526546.1
TMEM179B
transmembrane protein 179B
chr3_-_25824872 0.09 ENST00000308710.5
NGLY1
N-glycanase 1
chr3_+_109128837 0.09 ENST00000497996.1
RP11-702L6.4
RP11-702L6.4
chr11_+_111385497 0.09 ENST00000375618.4
ENST00000529167.1
ENST00000332814.6
C11orf88
chromosome 11 open reading frame 88
chr21_+_27543175 0.09 ENST00000608591.1
ENST00000609365.1
AP000230.1
AP000230.1

Network of associatons between targets according to the STRING database.

First level regulatory network of NFIA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 0.3 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.1 0.3 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 0.3 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.1 0.6 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.1 0.3 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.3 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1 0.5 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.2 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.2 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.2 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.3 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.2 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.0 0.2 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.0 0.1 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.0 0.2 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.2 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.3 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.0 GO:0015993 molecular hydrogen transport(GO:0015993)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.2 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.4 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.3 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.2 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.1 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.1 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.2 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.1 GO:2000224 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.0 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.1 GO:0071109 superior temporal gyrus development(GO:0071109)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.2 GO:0030578 PML body organization(GO:0030578)
0.0 0.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524) cardiac cell fate determination(GO:0060913)
0.0 0.1 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.2 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248)
0.0 0.4 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.0 0.1 GO:0033292 T-tubule organization(GO:0033292)
0.0 0.2 GO:2000782 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.2 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.2 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.2 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.5 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.0 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.3 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.0 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110)
0.0 0.1 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.3 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0072553 terminal button organization(GO:0072553)
0.0 0.1 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.0 0.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.1 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.0 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.1 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.0 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.2 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.3 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.2 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.1 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.2 GO:0030728 ovulation(GO:0030728)
0.0 0.0 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.0 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.0 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.0 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.0 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.4 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.2 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:0061589 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.0 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.3 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.3 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.2 GO:0032437 cuticular plate(GO:0032437)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.0 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 0.0 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0034711 inhibin binding(GO:0034711)
0.1 0.6 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.2 GO:0000224 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity(GO:0000224)
0.1 0.3 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1 0.3 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.2 GO:0031705 bombesin receptor binding(GO:0031705)
0.1 0.2 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.2 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.2 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.3 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.3 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0047017 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.0 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0031775 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.4 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.2 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151) transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.0 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.0 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.0 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.0 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.1 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation