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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NFAT5

Z-value: 0.73

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Transcription factors associated with NFAT5

Gene Symbol Gene ID Gene Info
NFAT5
ENSG00000102908.16 nuclear factor of activated T cells 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFAT5hg19_v2_chr16_+_69599861_69599887-0.777.6e-02Click!

Activity profile of NFAT5 motif

Sorted Z-values of NFAT5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_103589789 0.55 ENST00000558056.1
ENST00000560869.1
TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr6_+_138188351 0.51 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr14_+_95078714 0.49 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr12_+_26274917 0.43 ENST00000538142.1
SSPN
sarcospan
chr21_+_17792672 0.36 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr1_+_95975672 0.33 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1
RP11-286B14.1
chr4_+_105828492 0.31 ENST00000506148.1
RP11-556I14.1
RP11-556I14.1
chr2_+_47799601 0.30 ENST00000601243.1
AC138655.1
CDNA: FLJ23120 fis, clone LNG07989; HCG1987724; Uncharacterized protein
chr6_+_138188551 0.29 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr10_+_135122906 0.28 ENST00000368554.4
ZNF511
zinc finger protein 511
chr2_-_20101385 0.27 ENST00000431392.1
TTC32
tetratricopeptide repeat domain 32
chr12_+_46777450 0.25 ENST00000551503.1
RP11-96H19.1
RP11-96H19.1
chr14_+_97059070 0.24 ENST00000553378.1
ENST00000555496.1
RP11-433J8.1
RP11-433J8.1
chr13_-_30160925 0.24 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr12_+_120502441 0.23 ENST00000446727.2
CCDC64
coiled-coil domain containing 64
chr12_-_78934441 0.22 ENST00000546865.1
ENST00000547089.1
RP11-171L9.1
RP11-171L9.1
chr19_+_45254529 0.22 ENST00000444487.1
BCL3
B-cell CLL/lymphoma 3
chr14_-_25479811 0.21 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr16_+_89988259 0.21 ENST00000554444.1
ENST00000556565.1
TUBB3
Tubulin beta-3 chain
chr3_-_42003613 0.20 ENST00000414606.1
ULK4
unc-51 like kinase 4
chr3_+_122399697 0.20 ENST00000494811.1
PARP14
poly (ADP-ribose) polymerase family, member 14
chr17_+_45908974 0.20 ENST00000269025.4
LRRC46
leucine rich repeat containing 46
chr19_-_51017127 0.19 ENST00000389208.4
ASPDH
aspartate dehydrogenase domain containing
chr19_+_17905594 0.19 ENST00000599265.1
B3GNT3
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
chr15_-_49170219 0.19 ENST00000558220.1
ENST00000537958.1
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr4_+_17579110 0.19 ENST00000606142.1
LAP3
leucine aminopeptidase 3
chr3_-_9834463 0.18 ENST00000439043.1
TADA3
transcriptional adaptor 3
chr17_+_6915730 0.18 ENST00000548577.1
RNASEK
ribonuclease, RNase K
chr13_-_30996373 0.17 ENST00000420694.1
LINC01058
long intergenic non-protein coding RNA 1058
chr15_+_100348193 0.16 ENST00000558188.1
CTD-2054N24.2
Uncharacterized protein
chr7_+_141478242 0.16 ENST00000247881.2
TAS2R4
taste receptor, type 2, member 4
chrX_+_48755183 0.16 ENST00000376563.1
ENST00000376566.4
PQBP1
polyglutamine binding protein 1
chr17_+_38121772 0.16 ENST00000577447.1
GSDMA
gasdermin A
chr11_-_75062829 0.16 ENST00000393505.4
ARRB1
arrestin, beta 1
chr17_-_39093672 0.15 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr4_+_105828537 0.15 ENST00000515649.1
RP11-556I14.1
RP11-556I14.1
chr3_+_9834758 0.15 ENST00000485273.1
ENST00000433034.1
ENST00000397256.1
ARPC4
ARPC4-TTLL3
actin related protein 2/3 complex, subunit 4, 20kDa
ARPC4-TTLL3 readthrough
chr3_+_184079492 0.15 ENST00000456318.1
ENST00000412877.1
ENST00000438240.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr6_+_138188378 0.15 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr3_+_77088989 0.14 ENST00000461745.1
ROBO2
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr3_+_9834179 0.14 ENST00000498623.2
ARPC4
actin related protein 2/3 complex, subunit 4, 20kDa
chr1_-_246670614 0.14 ENST00000403792.3
SMYD3
SET and MYND domain containing 3
chr4_-_83483360 0.14 ENST00000449862.2
TMEM150C
transmembrane protein 150C
chr6_-_134495992 0.14 ENST00000475719.2
ENST00000367857.5
ENST00000237305.7
SGK1
serum/glucocorticoid regulated kinase 1
chr17_+_18684468 0.13 ENST00000574226.1
ENST00000575261.1
TVP23B
trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
chr19_+_44037546 0.13 ENST00000601282.1
ZNF575
zinc finger protein 575
chr12_+_22778291 0.13 ENST00000545979.1
ETNK1
ethanolamine kinase 1
chr7_+_65670186 0.13 ENST00000304842.5
ENST00000442120.1
TPST1
tyrosylprotein sulfotransferase 1
chr17_+_4853442 0.12 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chrX_+_135579670 0.12 ENST00000218364.4
HTATSF1
HIV-1 Tat specific factor 1
chr4_+_17578815 0.12 ENST00000226299.4
LAP3
leucine aminopeptidase 3
chr6_+_12007897 0.12 ENST00000437559.1
RP11-456H18.2
RP11-456H18.2
chr5_+_140186647 0.12 ENST00000512229.2
ENST00000356878.4
ENST00000530339.1
PCDHA4
protocadherin alpha 4
chr1_+_18958008 0.12 ENST00000420770.2
ENST00000400661.3
PAX7
paired box 7
chr3_+_177159744 0.11 ENST00000439009.1
LINC00578
long intergenic non-protein coding RNA 578
chr8_+_96037205 0.11 ENST00000396124.4
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr3_-_9834375 0.11 ENST00000343450.2
ENST00000301964.2
TADA3
transcriptional adaptor 3
chr18_-_33702078 0.11 ENST00000586829.1
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr3_+_9834227 0.11 ENST00000287613.7
ENST00000397261.3
ARPC4
actin related protein 2/3 complex, subunit 4, 20kDa
chr14_+_100594914 0.11 ENST00000554695.1
EVL
Enah/Vasp-like
chr5_-_96209315 0.11 ENST00000504056.1
CTD-2260A17.2
Uncharacterized protein
chr11_-_2924970 0.11 ENST00000533594.1
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr17_+_68071389 0.11 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr3_+_47866490 0.10 ENST00000457607.1
DHX30
DEAH (Asp-Glu-Ala-His) box helicase 30
chr3_+_25469724 0.10 ENST00000437042.2
RARB
retinoic acid receptor, beta
chr13_+_113030658 0.10 ENST00000414180.1
ENST00000443541.1
SPACA7
sperm acrosome associated 7
chr16_+_2079501 0.10 ENST00000563587.1
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr16_-_67514982 0.10 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
ATP6V0D1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr19_-_46706186 0.10 ENST00000601263.1
ENST00000598754.1
ENST00000594027.1
ENST00000598518.1
ENST00000599817.1
ENST00000595673.1
AC006262.5
AC006262.5
chr5_-_150521192 0.10 ENST00000523714.1
ENST00000521749.1
ANXA6
annexin A6
chr12_-_54813229 0.10 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr3_-_48594248 0.10 ENST00000545984.1
ENST00000232375.3
ENST00000416568.1
ENST00000383734.2
ENST00000541519.1
ENST00000412035.1
PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr1_-_246670519 0.10 ENST00000388985.4
ENST00000490107.1
SMYD3
SET and MYND domain containing 3
chr4_-_83483395 0.10 ENST00000515780.2
TMEM150C
transmembrane protein 150C
chr3_+_8543393 0.10 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1
LIM and cysteine-rich domains 1
chr1_+_201592013 0.10 ENST00000593583.1
AC096677.1
Uncharacterized protein ENSP00000471857
chr11_-_75062730 0.10 ENST00000420843.2
ENST00000360025.3
ARRB1
arrestin, beta 1
chr10_-_135122603 0.10 ENST00000368563.2
TUBGCP2
tubulin, gamma complex associated protein 2
chr17_-_46608272 0.09 ENST00000577092.1
ENST00000239174.6
HOXB1
homeobox B1
chr1_-_145470383 0.09 ENST00000369314.1
ENST00000369313.3
POLR3GL
polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like
chr15_-_102285007 0.09 ENST00000560292.2
RP11-89K11.1
Uncharacterized protein
chr7_-_100888337 0.09 ENST00000223136.4
FIS1
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
chr3_-_47950745 0.09 ENST00000429422.1
MAP4
microtubule-associated protein 4
chr3_+_127770455 0.09 ENST00000464451.1
SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr11_+_65154070 0.09 ENST00000317568.5
ENST00000531296.1
ENST00000533782.1
ENST00000355991.5
ENST00000416776.2
ENST00000526201.1
FRMD8
FERM domain containing 8
chr11_+_131240593 0.09 ENST00000539799.1
NTM
neurotrimin
chr6_-_31926208 0.08 ENST00000454913.1
ENST00000436289.2
NELFE
negative elongation factor complex member E
chr17_+_68071458 0.08 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr6_-_131291572 0.08 ENST00000529208.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr6_+_116832789 0.08 ENST00000368599.3
FAM26E
family with sequence similarity 26, member E
chr13_-_67804445 0.08 ENST00000456367.1
ENST00000377861.3
ENST00000544246.1
PCDH9
protocadherin 9
chr1_-_85870177 0.08 ENST00000542148.1
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr12_+_10365082 0.08 ENST00000545859.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr12_+_101988627 0.08 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1
myosin binding protein C, slow type
chr1_+_155006300 0.08 ENST00000295542.1
ENST00000392480.1
ENST00000423025.2
ENST00000368419.2
DCST1
DC-STAMP domain containing 1
chr10_-_124639062 0.08 ENST00000368898.3
ENST00000368896.1
ENST00000545804.1
FAM24B
CUZD1
family with sequence similarity 24, member B
CUB and zona pellucida-like domains 1
chr3_+_49027308 0.07 ENST00000383729.4
ENST00000343546.4
P4HTM
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr15_+_54901540 0.07 ENST00000539562.2
UNC13C
unc-13 homolog C (C. elegans)
chr6_+_4890226 0.07 ENST00000343762.5
CDYL
chromodomain protein, Y-like
chr11_+_60145948 0.07 ENST00000300184.3
ENST00000358246.1
MS4A7
membrane-spanning 4-domains, subfamily A, member 7
chr7_+_95401851 0.07 ENST00000447467.2
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr12_+_101988774 0.07 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
MYBPC1
myosin binding protein C, slow type
chr4_-_74847800 0.07 ENST00000296029.3
PF4
platelet factor 4
chrX_-_128977875 0.07 ENST00000406492.2
ZDHHC9
zinc finger, DHHC-type containing 9
chr5_-_137090028 0.07 ENST00000314940.4
HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr15_-_75134992 0.07 ENST00000568667.1
ULK3
unc-51 like kinase 3
chr14_+_100848311 0.07 ENST00000542471.2
WDR25
WD repeat domain 25
chr4_-_76861392 0.07 ENST00000505594.1
NAAA
N-acylethanolamine acid amidase
chr7_-_92855762 0.07 ENST00000453812.2
ENST00000394468.2
HEPACAM2
HEPACAM family member 2
chr17_+_6658878 0.07 ENST00000574394.1
XAF1
XIAP associated factor 1
chr16_-_85969774 0.07 ENST00000598933.1
RP11-542M13.3
RP11-542M13.3
chr17_+_17991197 0.07 ENST00000225729.3
DRG2
developmentally regulated GTP binding protein 2
chr2_+_108994466 0.07 ENST00000272452.2
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr12_-_108991778 0.06 ENST00000549447.1
TMEM119
transmembrane protein 119
chr6_+_44094627 0.06 ENST00000259746.9
TMEM63B
transmembrane protein 63B
chr7_+_1127723 0.06 ENST00000397088.3
GPER1
G protein-coupled estrogen receptor 1
chr6_+_130339710 0.06 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr1_+_111889212 0.06 ENST00000369737.4
PIFO
primary cilia formation
chr16_+_2079637 0.06 ENST00000561844.1
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chrX_+_18725758 0.06 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1
protein phosphatase, EF-hand calcium binding domain 1
chr7_+_1126461 0.06 ENST00000297469.3
GPER1
G protein-coupled estrogen receptor 1
chr19_+_49999631 0.06 ENST00000270625.2
ENST00000596873.1
ENST00000594493.1
ENST00000599561.1
RPS11
ribosomal protein S11
chr12_+_53848549 0.06 ENST00000439930.3
ENST00000548933.1
ENST00000562264.1
PCBP2
poly(rC) binding protein 2
chr6_+_152011628 0.06 ENST00000404742.1
ENST00000440973.1
ESR1
estrogen receptor 1
chr1_-_155006254 0.06 ENST00000295536.5
DCST2
DC-STAMP domain containing 2
chr18_+_11103 0.06 ENST00000575820.1
ENST00000572573.1
AP005530.1
AP005530.1
chr14_+_91580357 0.06 ENST00000298858.4
ENST00000521081.1
ENST00000520328.1
ENST00000256324.10
ENST00000524232.1
ENST00000522170.1
ENST00000519950.1
ENST00000523879.1
ENST00000521077.2
ENST00000518665.2
C14orf159
chromosome 14 open reading frame 159
chr17_-_202579 0.06 ENST00000577079.1
ENST00000331302.7
ENST00000536489.2
RPH3AL
rabphilin 3A-like (without C2 domains)
chr19_+_17420340 0.06 ENST00000359866.4
DDA1
DET1 and DDB1 associated 1
chr7_-_100888313 0.06 ENST00000442303.1
FIS1
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
chr1_-_115300592 0.06 ENST00000261443.5
ENST00000534699.1
ENST00000339438.6
ENST00000529046.1
ENST00000525970.1
ENST00000369530.1
ENST00000530886.1
CSDE1
cold shock domain containing E1, RNA-binding
chr14_+_39644425 0.06 ENST00000556530.1
PNN
pinin, desmosome associated protein
chr2_+_48796120 0.06 ENST00000394754.1
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chr12_+_110011571 0.06 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK
mevalonate kinase
chr11_-_67120974 0.06 ENST00000539074.1
ENST00000312419.3
POLD4
polymerase (DNA-directed), delta 4, accessory subunit
chr2_-_223163465 0.06 ENST00000409828.3
ENST00000350526.4
ENST00000258387.5
ENST00000409551.3
ENST00000392069.2
ENST00000344493.4
ENST00000336840.6
ENST00000392070.2
PAX3
paired box 3
chr2_-_242211359 0.05 ENST00000444092.1
HDLBP
high density lipoprotein binding protein
chr6_+_30103885 0.05 ENST00000396581.1
TRIM40
tripartite motif containing 40
chr7_+_1126437 0.05 ENST00000413368.1
ENST00000397092.1
GPER1
G protein-coupled estrogen receptor 1
chr19_+_14142535 0.05 ENST00000263379.2
IL27RA
interleukin 27 receptor, alpha
chr15_+_43885799 0.05 ENST00000449946.1
ENST00000417289.1
CKMT1B
creatine kinase, mitochondrial 1B
chr7_+_128399002 0.05 ENST00000493278.1
CALU
calumenin
chr3_+_8543561 0.05 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr1_-_57045228 0.05 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr7_-_102119342 0.05 ENST00000393794.3
ENST00000292614.5
POLR2J
polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
chr5_+_140261703 0.05 ENST00000409494.1
ENST00000289272.2
PCDHA13
protocadherin alpha 13
chr19_+_42212501 0.05 ENST00000398599.4
CEACAM5
carcinoembryonic antigen-related cell adhesion molecule 5
chr19_+_859425 0.05 ENST00000327726.6
CFD
complement factor D (adipsin)
chr3_-_49131013 0.05 ENST00000424300.1
QRICH1
glutamine-rich 1
chr18_-_52989217 0.05 ENST00000570287.2
TCF4
transcription factor 4
chr1_-_155006224 0.05 ENST00000368424.3
DCST2
DC-STAMP domain containing 2
chr6_+_73331814 0.05 ENST00000370392.1
KCNQ5
potassium voltage-gated channel, KQT-like subfamily, member 5
chr7_+_149570049 0.05 ENST00000421974.2
ENST00000456496.2
ATP6V0E2
ATPase, H+ transporting V0 subunit e2
chr4_-_155511887 0.05 ENST00000302053.3
ENST00000403106.3
FGA
fibrinogen alpha chain
chr12_+_10365404 0.05 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr11_-_18063973 0.05 ENST00000528338.1
TPH1
tryptophan hydroxylase 1
chr17_+_40950900 0.05 ENST00000588527.1
CNTD1
cyclin N-terminal domain containing 1
chr11_+_131781290 0.05 ENST00000425719.2
ENST00000374784.1
NTM
neurotrimin
chr16_-_51185172 0.05 ENST00000251020.4
SALL1
spalt-like transcription factor 1
chr19_-_44100275 0.04 ENST00000422989.1
ENST00000598324.1
IRGQ
immunity-related GTPase family, Q
chr10_-_69455873 0.04 ENST00000433211.2
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr17_+_9745786 0.04 ENST00000304773.5
GLP2R
glucagon-like peptide 2 receptor
chr1_-_169599314 0.04 ENST00000367786.2
ENST00000458599.2
ENST00000367795.2
ENST00000263686.6
SELP
selectin P (granule membrane protein 140kDa, antigen CD62)
chr19_+_48828788 0.04 ENST00000594198.1
ENST00000597279.1
ENST00000593437.1
EMP3
epithelial membrane protein 3
chr11_+_119039069 0.04 ENST00000422249.1
NLRX1
NLR family member X1
chr12_+_119772502 0.04 ENST00000536742.1
ENST00000327554.2
CCDC60
coiled-coil domain containing 60
chr2_-_238305397 0.04 ENST00000409809.1
COL6A3
collagen, type VI, alpha 3
chr7_+_30174574 0.04 ENST00000409688.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr7_-_99698338 0.04 ENST00000354230.3
ENST00000425308.1
MCM7
minichromosome maintenance complex component 7
chr14_-_30396948 0.04 ENST00000331968.5
PRKD1
protein kinase D1
chr15_+_45028520 0.04 ENST00000329464.4
TRIM69
tripartite motif containing 69
chr8_-_128231299 0.04 ENST00000500112.1
CCAT1
colon cancer associated transcript 1 (non-protein coding)
chr2_-_161056762 0.04 ENST00000428609.2
ENST00000409967.2
ITGB6
integrin, beta 6
chr2_+_143635067 0.04 ENST00000264170.4
KYNU
kynureninase
chr20_-_43753104 0.04 ENST00000372785.3
WFDC12
WAP four-disulfide core domain 12
chr10_-_97175444 0.04 ENST00000486141.2
SORBS1
sorbin and SH3 domain containing 1
chr1_-_169599353 0.04 ENST00000367793.2
ENST00000367794.2
ENST00000367792.2
ENST00000367791.2
ENST00000367788.2
SELP
selectin P (granule membrane protein 140kDa, antigen CD62)
chr7_+_70229899 0.04 ENST00000443672.1
AUTS2
autism susceptibility candidate 2
chrX_-_153583257 0.03 ENST00000438732.1
FLNA
filamin A, alpha
chr12_+_53848505 0.03 ENST00000552819.1
ENST00000455667.3
PCBP2
poly(rC) binding protein 2
chr1_-_201346761 0.03 ENST00000455702.1
ENST00000422165.1
ENST00000367318.5
ENST00000367320.2
ENST00000438742.1
ENST00000412633.1
ENST00000458432.2
ENST00000421663.2
ENST00000367322.1
ENST00000509001.1
TNNT2
troponin T type 2 (cardiac)
chr17_-_1613663 0.03 ENST00000330676.6
TLCD2
TLC domain containing 2
chr4_+_69313145 0.03 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chr3_+_63805017 0.03 ENST00000295896.8
C3orf49
chromosome 3 open reading frame 49
chr7_+_95401877 0.03 ENST00000524053.1
ENST00000324972.6
ENST00000537881.1
ENST00000437599.1
ENST00000359388.4
ENST00000413338.1
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr20_-_23731569 0.03 ENST00000304749.2
CST1
cystatin SN
chr2_+_238877424 0.03 ENST00000434655.1
UBE2F
ubiquitin-conjugating enzyme E2F (putative)
chr17_-_40950698 0.03 ENST00000328434.7
COA3
cytochrome c oxidase assembly factor 3
chr6_+_153071925 0.03 ENST00000367244.3
ENST00000367243.3
VIP
vasoactive intestinal peptide
chr1_+_111888890 0.03 ENST00000369738.4
PIFO
primary cilia formation
chr17_+_38083977 0.03 ENST00000578802.1
ENST00000578478.1
ENST00000582263.1
RP11-387H17.4
RP11-387H17.4
chr11_+_119039414 0.02 ENST00000409991.1
ENST00000292199.2
ENST00000409265.4
ENST00000409109.1
NLRX1
NLR family member X1
chr1_-_204436344 0.02 ENST00000367184.2
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr5_-_35230771 0.02 ENST00000342362.5
PRLR
prolactin receptor
chrX_+_70752917 0.02 ENST00000373719.3
OGT
O-linked N-acetylglucosamine (GlcNAc) transferase
chr9_+_70856899 0.02 ENST00000377342.5
ENST00000478048.1
CBWD3
COBW domain containing 3
chr12_-_82152444 0.02 ENST00000549325.1
ENST00000550584.2
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr11_+_73359719 0.02 ENST00000535129.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr15_+_45028753 0.02 ENST00000338264.4
TRIM69
tripartite motif containing 69
chr1_-_16345245 0.02 ENST00000311890.9
HSPB7
heat shock 27kDa protein family, member 7 (cardiovascular)

Network of associatons between targets according to the STRING database.

First level regulatory network of NFAT5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0072573 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of osteoclast proliferation(GO:0090291) negative regulation of CD40 signaling pathway(GO:2000349)
0.1 0.2 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.1 0.2 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 0.2 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264)
0.0 0.8 GO:0051601 exocyst localization(GO:0051601)
0.0 0.3 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.1 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.3 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925) apoptotic process involved in luteolysis(GO:0061364)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.5 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.1 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.0 0.0 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.1 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0021527 skeletal muscle satellite cell differentiation(GO:0014816) spinal cord association neuron differentiation(GO:0021527)
0.0 0.0 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 0.0 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.0 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:0003406 retinal pigment epithelium development(GO:0003406)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.1 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.3 GO:0030914 SAGA complex(GO:0000124) STAGA complex(GO:0030914)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031896 vasopressin receptor binding(GO:0031893) V2 vasopressin receptor binding(GO:0031896)
0.1 0.2 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.0 0.9 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.1 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.0 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0042806 fucose binding(GO:0042806) glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling