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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MZF1

Z-value: 0.43

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Transcription factors associated with MZF1

Gene Symbol Gene ID Gene Info
MZF1
ENSG00000099326.4 myeloid zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MZF1hg19_v2_chr19_-_59084647_590847210.758.4e-02Click!

Activity profile of MZF1 motif

Sorted Z-values of MZF1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_61765315 0.36 ENST00000406957.1
ENST00000401558.2
XPO1
exportin 1 (CRM1 homolog, yeast)
chr3_-_169381166 0.35 ENST00000486748.1
MECOM
MDS1 and EVI1 complex locus
chr19_-_10628098 0.30 ENST00000590601.1
S1PR5
sphingosine-1-phosphate receptor 5
chr4_-_56412713 0.30 ENST00000435527.2
CLOCK
clock circadian regulator
chr2_+_206950095 0.25 ENST00000435627.1
AC007383.3
AC007383.3
chr14_-_71107921 0.25 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
CTD-2540L5.5
CTD-2540L5.6
chrX_-_108868390 0.24 ENST00000372101.2
KCNE1L
KCNE1-like
chr5_+_115177178 0.22 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr3_+_119814070 0.21 ENST00000469070.1
RP11-18H7.1
RP11-18H7.1
chr17_+_2264983 0.20 ENST00000574650.1
SGSM2
small G protein signaling modulator 2
chr18_-_53255766 0.19 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr1_+_6845578 0.19 ENST00000467404.2
ENST00000439411.2
CAMTA1
calmodulin binding transcription activator 1
chrX_-_119694538 0.19 ENST00000371322.5
CUL4B
cullin 4B
chr14_-_36990061 0.18 ENST00000546983.1
NKX2-1
NK2 homeobox 1
chr17_-_56065540 0.18 ENST00000583932.1
VEZF1
vascular endothelial zinc finger 1
chr5_-_81046904 0.18 ENST00000515395.1
SSBP2
single-stranded DNA binding protein 2
chr12_+_65996599 0.17 ENST00000539116.1
ENST00000541391.1
RP11-221N13.3
RP11-221N13.3
chr8_+_145490549 0.17 ENST00000340695.2
SCXA
scleraxis homolog A (mouse)
chr1_-_167906277 0.17 ENST00000271373.4
MPC2
mitochondrial pyruvate carrier 2
chr20_+_2083540 0.17 ENST00000400064.3
STK35
serine/threonine kinase 35
chr1_-_11115877 0.16 ENST00000490101.1
SRM
spermidine synthase
chr17_-_36904437 0.16 ENST00000585100.1
ENST00000360797.2
ENST00000578109.1
ENST00000579882.1
PCGF2
polycomb group ring finger 2
chr17_+_42634844 0.15 ENST00000315323.3
FZD2
frizzled family receptor 2
chr3_-_93692681 0.14 ENST00000348974.4
PROS1
protein S (alpha)
chr15_-_83224682 0.14 ENST00000562833.1
RP11-152F13.10
RP11-152F13.10
chr7_-_112579869 0.14 ENST00000297145.4
C7orf60
chromosome 7 open reading frame 60
chr2_+_145780767 0.14 ENST00000599358.1
ENST00000596278.1
ENST00000596747.1
ENST00000608652.1
ENST00000609705.1
ENST00000608432.1
ENST00000596970.1
ENST00000602041.1
ENST00000601578.1
ENST00000596034.1
ENST00000414195.2
ENST00000594837.1
TEX41
testis expressed 41 (non-protein coding)
chr13_-_52026730 0.14 ENST00000420668.2
INTS6
integrator complex subunit 6
chr16_-_79634595 0.14 ENST00000326043.4
ENST00000393350.1
MAF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr3_-_12200851 0.14 ENST00000287814.4
TIMP4
TIMP metallopeptidase inhibitor 4
chr1_+_78470530 0.14 ENST00000370763.5
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr5_-_81046841 0.14 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
SSBP2
single-stranded DNA binding protein 2
chr15_+_75640068 0.13 ENST00000565051.1
ENST00000564257.1
ENST00000567005.1
NEIL1
nei endonuclease VIII-like 1 (E. coli)
chr14_-_76447494 0.13 ENST00000238682.3
TGFB3
transforming growth factor, beta 3
chr3_-_88108192 0.13 ENST00000309534.6
CGGBP1
CGG triplet repeat binding protein 1
chr1_+_167599532 0.13 ENST00000537350.1
RCSD1
RCSD domain containing 1
chr15_-_71055769 0.13 ENST00000539319.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr7_-_79082867 0.13 ENST00000419488.1
ENST00000354212.4
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr11_-_94965667 0.12 ENST00000542176.1
ENST00000278499.2
SESN3
sestrin 3
chr2_-_26251481 0.12 ENST00000599234.1
AC013449.1
Uncharacterized protein
chr7_-_127032363 0.12 ENST00000393312.1
ZNF800
zinc finger protein 800
chr6_-_31869769 0.12 ENST00000375527.2
ZBTB12
zinc finger and BTB domain containing 12
chr5_-_81046922 0.12 ENST00000514493.1
ENST00000320672.4
SSBP2
single-stranded DNA binding protein 2
chr4_+_30721968 0.12 ENST00000361762.2
PCDH7
protocadherin 7
chr2_+_149402989 0.12 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr9_+_34653861 0.12 ENST00000556792.1
ENST00000318041.9
ENST00000378817.4
IL11RA
interleukin 11 receptor, alpha
chr14_-_77495007 0.12 ENST00000238647.3
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr17_+_38465441 0.12 ENST00000577646.1
ENST00000254066.5
RARA
retinoic acid receptor, alpha
chr17_+_29421987 0.12 ENST00000431387.4
NF1
neurofibromin 1
chr17_-_49337392 0.12 ENST00000376381.2
ENST00000586178.1
MBTD1
mbt domain containing 1
chr11_+_86748957 0.12 ENST00000526733.1
ENST00000532959.1
TMEM135
transmembrane protein 135
chr5_-_149465990 0.12 ENST00000543093.1
CSF1R
colony stimulating factor 1 receptor
chr1_-_67390474 0.12 ENST00000371023.3
ENST00000371022.3
ENST00000371026.3
ENST00000431318.1
WDR78
WD repeat domain 78
chr12_+_57522439 0.12 ENST00000338962.4
LRP1
low density lipoprotein receptor-related protein 1
chr17_+_26369865 0.12 ENST00000582037.1
NLK
nemo-like kinase
chr6_-_86353510 0.12 ENST00000444272.1
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr12_+_57522692 0.11 ENST00000554174.1
LRP1
low density lipoprotein receptor-related protein 1
chr10_+_102672712 0.11 ENST00000370271.3
ENST00000370269.3
ENST00000609386.1
FAM178A
family with sequence similarity 178, member A
chr19_+_13135439 0.11 ENST00000586873.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr2_-_61765732 0.11 ENST00000443240.1
ENST00000436018.1
XPO1
exportin 1 (CRM1 homolog, yeast)
chr4_+_184427235 0.11 ENST00000412117.1
ENST00000434682.2
ING2
inhibitor of growth family, member 2
chr18_-_658244 0.11 ENST00000585033.1
ENST00000323813.3
C18orf56
chromosome 18 open reading frame 56
chr22_-_31742218 0.11 ENST00000266269.5
ENST00000405309.3
ENST00000351933.4
PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr22_+_40440804 0.11 ENST00000441751.1
ENST00000301923.9
TNRC6B
trinucleotide repeat containing 6B
chr11_+_130184888 0.11 ENST00000602376.1
ENST00000532116.3
ENST00000602310.1
RP11-121M22.1
RP11-121M22.1
chr5_+_32531893 0.10 ENST00000512913.1
SUB1
SUB1 homolog (S. cerevisiae)
chr8_+_22250334 0.10 ENST00000520832.1
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr7_-_112579673 0.10 ENST00000432572.1
C7orf60
chromosome 7 open reading frame 60
chr11_+_86511549 0.10 ENST00000533902.2
PRSS23
protease, serine, 23
chr15_-_74043816 0.10 ENST00000379822.4
C15orf59
chromosome 15 open reading frame 59
chr2_+_46769798 0.10 ENST00000238738.4
RHOQ
ras homolog family member Q
chr10_+_21823243 0.10 ENST00000307729.7
ENST00000377091.2
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr14_+_32546145 0.10 ENST00000556611.1
ENST00000539826.2
ARHGAP5
Rho GTPase activating protein 5
chr7_+_114562172 0.10 ENST00000393486.1
ENST00000257724.3
MDFIC
MyoD family inhibitor domain containing
chr11_-_35547277 0.10 ENST00000527605.1
PAMR1
peptidase domain containing associated with muscle regeneration 1
chr7_-_127032741 0.10 ENST00000393313.1
ENST00000265827.3
ENST00000434602.1
ZNF800
zinc finger protein 800
chr12_+_6881678 0.10 ENST00000441671.2
ENST00000203629.2
LAG3
lymphocyte-activation gene 3
chrX_-_13835461 0.10 ENST00000316715.4
ENST00000356942.5
GPM6B
glycoprotein M6B
chr4_-_153274078 0.10 ENST00000263981.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr1_+_150229554 0.10 ENST00000369111.4
CA14
carbonic anhydrase XIV
chr9_-_6007787 0.10 ENST00000399933.3
ENST00000381461.2
ENST00000513355.2
KIAA2026
KIAA2026
chr1_-_159915386 0.10 ENST00000361509.3
ENST00000368094.1
IGSF9
immunoglobulin superfamily, member 9
chr1_+_6845497 0.10 ENST00000473578.1
ENST00000557126.1
CAMTA1
calmodulin binding transcription activator 1
chrX_+_123095546 0.10 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
STAG2
stromal antigen 2
chr2_+_220325977 0.10 ENST00000396686.1
ENST00000396689.2
SPEG
SPEG complex locus
chr2_-_172017393 0.09 ENST00000442919.2
TLK1
tousled-like kinase 1
chr3_-_168864315 0.09 ENST00000475754.1
ENST00000484519.1
MECOM
MDS1 and EVI1 complex locus
chr19_-_59084647 0.09 ENST00000594234.1
ENST00000596039.1
MZF1
myeloid zinc finger 1
chr1_-_221915418 0.09 ENST00000323825.3
ENST00000366899.3
DUSP10
dual specificity phosphatase 10
chr19_-_49371711 0.09 ENST00000355496.5
ENST00000263265.6
PLEKHA4
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr8_-_75233563 0.09 ENST00000342232.4
JPH1
junctophilin 1
chr11_-_35547151 0.09 ENST00000378878.3
ENST00000529303.1
ENST00000278360.3
PAMR1
peptidase domain containing associated with muscle regeneration 1
chr17_-_48943706 0.09 ENST00000499247.2
TOB1
transducer of ERBB2, 1
chrX_-_119695279 0.09 ENST00000336592.6
CUL4B
cullin 4B
chr2_-_61697862 0.09 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr2_-_45236540 0.09 ENST00000303077.6
SIX2
SIX homeobox 2
chr2_+_220325441 0.09 ENST00000396688.1
SPEG
SPEG complex locus
chr1_+_67390578 0.09 ENST00000371018.3
ENST00000355977.6
ENST00000357692.2
ENST00000401041.1
ENST00000371016.1
ENST00000371014.1
ENST00000371012.2
MIER1
mesoderm induction early response 1, transcriptional regulator
chr1_-_150208412 0.09 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr17_+_73089382 0.09 ENST00000538213.2
ENST00000584118.1
SLC16A5
solute carrier family 16 (monocarboxylate transporter), member 5
chr8_-_101733794 0.09 ENST00000523555.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chrX_+_123095860 0.09 ENST00000428941.1
STAG2
stromal antigen 2
chr11_+_86748863 0.09 ENST00000340353.7
TMEM135
transmembrane protein 135
chr3_-_50360165 0.09 ENST00000428028.1
HYAL2
hyaluronoglucosaminidase 2
chr12_-_7077125 0.09 ENST00000545555.2
PHB2
prohibitin 2
chr3_+_110790590 0.08 ENST00000485303.1
PVRL3
poliovirus receptor-related 3
chrX_-_135849484 0.08 ENST00000370620.1
ENST00000535227.1
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr10_+_21823079 0.08 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr14_-_64010046 0.08 ENST00000337537.3
PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr17_+_79990058 0.08 ENST00000584341.1
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr4_+_129730947 0.08 ENST00000452328.2
ENST00000504089.1
PHF17
jade family PHD finger 1
chr16_+_22019404 0.08 ENST00000542527.2
ENST00000569656.1
ENST00000562695.1
C16orf52
chromosome 16 open reading frame 52
chr17_+_29421900 0.08 ENST00000358273.4
ENST00000356175.3
NF1
neurofibromin 1
chr11_+_86749035 0.08 ENST00000305494.5
ENST00000535167.1
TMEM135
transmembrane protein 135
chr17_-_46667594 0.08 ENST00000476342.1
ENST00000460160.1
ENST00000472863.1
HOXB3
homeobox B3
chr17_-_7193711 0.08 ENST00000571464.1
YBX2
Y box binding protein 2
chr2_+_61108650 0.08 ENST00000295025.8
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr8_+_104831472 0.08 ENST00000262231.10
ENST00000507740.1
RIMS2
regulating synaptic membrane exocytosis 2
chr5_+_82767284 0.08 ENST00000265077.3
VCAN
versican
chr11_+_86511569 0.08 ENST00000441050.1
PRSS23
protease, serine, 23
chr1_+_156052354 0.08 ENST00000368301.2
LMNA
lamin A/C
chr3_-_182698381 0.08 ENST00000292782.4
DCUN1D1
DCN1, defective in cullin neddylation 1, domain containing 1
chrX_+_123095890 0.08 ENST00000435215.1
STAG2
stromal antigen 2
chr2_+_46926326 0.08 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr11_+_47279504 0.08 ENST00000441012.2
ENST00000437276.1
ENST00000436029.1
ENST00000467728.1
ENST00000405853.3
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr1_+_160370344 0.08 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr19_+_13135790 0.08 ENST00000358552.3
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr14_+_32546485 0.08 ENST00000345122.3
ENST00000432921.1
ENST00000433497.1
ARHGAP5
Rho GTPase activating protein 5
chr17_+_39968926 0.08 ENST00000585664.1
ENST00000585922.1
ENST00000429461.1
FKBP10
FK506 binding protein 10, 65 kDa
chr13_+_76123883 0.08 ENST00000377595.3
UCHL3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr4_-_168155577 0.07 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr3_-_93692781 0.07 ENST00000394236.3
PROS1
protein S (alpha)
chr19_-_38916839 0.07 ENST00000433821.2
ENST00000426920.2
ENST00000587753.1
ENST00000454404.2
ENST00000293062.9
RASGRP4
RAS guanyl releasing protein 4
chr22_+_38321840 0.07 ENST00000454685.1
MICALL1
MICAL-like 1
chr3_-_178865747 0.07 ENST00000435560.1
RP11-360P21.2
RP11-360P21.2
chr16_-_67260901 0.07 ENST00000341546.3
ENST00000409509.1
ENST00000433915.1
ENST00000454102.2
LRRC29
AC040160.1
leucine rich repeat containing 29
Uncharacterized protein; cDNA FLJ57407, weakly similar to Mus musculus leucine rich repeat containing 29 (Lrrc29), mRNA
chr3_+_73045936 0.07 ENST00000356692.5
ENST00000488810.1
ENST00000394284.3
ENST00000295862.9
ENST00000495566.1
PPP4R2
protein phosphatase 4, regulatory subunit 2
chr20_-_42816206 0.07 ENST00000372980.3
JPH2
junctophilin 2
chr15_-_71055878 0.07 ENST00000322954.6
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr8_-_38126635 0.07 ENST00000529359.1
PPAPDC1B
phosphatidic acid phosphatase type 2 domain containing 1B
chr19_-_42759300 0.07 ENST00000222329.4
ERF
Ets2 repressor factor
chr9_-_122131696 0.07 ENST00000373964.2
ENST00000265922.3
BRINP1
bone morphogenetic protein/retinoic acid inducible neural-specific 1
chr19_+_34745442 0.07 ENST00000299505.6
ENST00000588470.1
ENST00000589583.1
ENST00000588338.2
KIAA0355
KIAA0355
chr6_-_52860171 0.07 ENST00000370963.4
GSTA4
glutathione S-transferase alpha 4
chr1_-_113162040 0.07 ENST00000358039.4
ENST00000369668.2
ST7L
suppression of tumorigenicity 7 like
chr6_+_87865262 0.07 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292
zinc finger protein 292
chr8_-_21988558 0.07 ENST00000312841.8
HR
hair growth associated
chr14_+_32546274 0.07 ENST00000396582.2
ARHGAP5
Rho GTPase activating protein 5
chr3_-_169381183 0.07 ENST00000494292.1
MECOM
MDS1 and EVI1 complex locus
chr16_+_28505955 0.07 ENST00000564831.1
ENST00000328423.5
ENST00000431282.1
APOBR
apolipoprotein B receptor
chr2_+_219283815 0.07 ENST00000248444.5
ENST00000454069.1
ENST00000392114.2
VIL1
villin 1
chr4_+_140222609 0.07 ENST00000296543.5
ENST00000398947.1
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr18_+_19321281 0.07 ENST00000261537.6
MIB1
mindbomb E3 ubiquitin protein ligase 1
chr3_-_48601206 0.07 ENST00000273610.3
UCN2
urocortin 2
chr10_+_98592009 0.07 ENST00000540664.1
ENST00000371103.3
LCOR
ligand dependent nuclear receptor corepressor
chr4_+_174089904 0.07 ENST00000265000.4
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr2_+_121493717 0.07 ENST00000418323.1
GLI2
GLI family zinc finger 2
chr3_+_110790715 0.07 ENST00000319792.3
PVRL3
poliovirus receptor-related 3
chr9_-_74525847 0.07 ENST00000377041.2
ABHD17B
abhydrolase domain containing 17B
chr9_-_119449483 0.07 ENST00000288520.5
ENST00000358637.4
ENST00000341734.4
ASTN2
astrotactin 2
chr7_+_130794878 0.07 ENST00000416992.2
MKLN1
muskelin 1, intracellular mediator containing kelch motifs
chrX_-_109561294 0.07 ENST00000372059.2
ENST00000262844.5
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr1_+_93913665 0.07 ENST00000271234.7
ENST00000370256.4
ENST00000260506.8
FNBP1L
formin binding protein 1-like
chr15_-_33447055 0.07 ENST00000559047.1
ENST00000561249.1
FMN1
formin 1
chr11_-_96076334 0.07 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr15_-_49103184 0.06 ENST00000399334.3
ENST00000325747.5
CEP152
centrosomal protein 152kDa
chr1_+_154301264 0.06 ENST00000341822.2
ATP8B2
ATPase, aminophospholipid transporter, class I, type 8B, member 2
chr5_+_49962495 0.06 ENST00000515175.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr17_+_38278530 0.06 ENST00000398532.4
MSL1
male-specific lethal 1 homolog (Drosophila)
chr2_-_206950781 0.06 ENST00000403263.1
INO80D
INO80 complex subunit D
chr13_+_95364963 0.06 ENST00000438290.2
SOX21-AS1
SOX21 antisense RNA 1 (head to head)
chr14_-_36990354 0.06 ENST00000518149.1
NKX2-1
NK2 homeobox 1
chr15_-_37392724 0.06 ENST00000424352.2
MEIS2
Meis homeobox 2
chr19_-_4065730 0.06 ENST00000601588.1
ZBTB7A
zinc finger and BTB domain containing 7A
chr15_-_66084621 0.06 ENST00000564674.1
DENND4A
DENN/MADD domain containing 4A
chr13_-_31736027 0.06 ENST00000380406.5
ENST00000320027.5
ENST00000380405.4
HSPH1
heat shock 105kDa/110kDa protein 1
chr5_-_94620239 0.06 ENST00000515393.1
MCTP1
multiple C2 domains, transmembrane 1
chr1_+_24117662 0.06 ENST00000420982.1
ENST00000374505.2
LYPLA2
lysophospholipase II
chr2_+_45878407 0.06 ENST00000421201.1
PRKCE
protein kinase C, epsilon
chr3_+_9944303 0.06 ENST00000421412.1
ENST00000295980.3
IL17RE
interleukin 17 receptor E
chr16_-_67260691 0.06 ENST00000447579.1
ENST00000393992.1
ENST00000424285.1
LRRC29
leucine rich repeat containing 29
chr1_-_53018654 0.06 ENST00000257177.4
ENST00000355809.4
ENST00000528642.1
ENST00000470626.1
ENST00000371544.3
ZCCHC11
zinc finger, CCHC domain containing 11
chr17_-_37764128 0.06 ENST00000302584.4
NEUROD2
neuronal differentiation 2
chr4_-_84035905 0.06 ENST00000311507.4
PLAC8
placenta-specific 8
chr4_-_153457197 0.06 ENST00000281708.4
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr7_-_100061869 0.06 ENST00000332375.3
C7orf61
chromosome 7 open reading frame 61
chr19_-_46272462 0.06 ENST00000317578.6
SIX5
SIX homeobox 5
chr19_+_3708338 0.06 ENST00000590545.1
TJP3
tight junction protein 3
chr4_+_88928777 0.06 ENST00000237596.2
PKD2
polycystic kidney disease 2 (autosomal dominant)
chr4_-_76598296 0.06 ENST00000395719.3
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr8_+_95653840 0.06 ENST00000520385.1
ESRP1
epithelial splicing regulatory protein 1
chr17_+_46132037 0.06 ENST00000582155.1
ENST00000583378.1
ENST00000536222.1
NFE2L1
nuclear factor, erythroid 2-like 1
chr12_+_53443963 0.06 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr22_-_46373004 0.06 ENST00000339464.4
WNT7B
wingless-type MMTV integration site family, member 7B
chr8_+_55466915 0.06 ENST00000522711.2
RP11-53M11.3
RP11-53M11.3
chr1_+_89149905 0.06 ENST00000316005.7
ENST00000370521.3
ENST00000370505.3
PKN2
protein kinase N2
chr7_-_17980091 0.06 ENST00000409389.1
ENST00000409604.1
ENST00000428135.3
SNX13
sorting nexin 13
chr3_+_181429704 0.06 ENST00000431565.2
ENST00000325404.1
SOX2
SRY (sex determining region Y)-box 2
chr15_-_51058005 0.06 ENST00000261854.5
SPPL2A
signal peptide peptidase like 2A
chr4_-_89205879 0.06 ENST00000608933.1
ENST00000315194.4
ENST00000514204.1
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K

Network of associatons between targets according to the STRING database.

First level regulatory network of MZF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.2 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.5 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.1 GO:0042704 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.0 0.3 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.1 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.0 0.3 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.2 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.0 0.1 GO:1904799 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0 0.1 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.2 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.1 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.1 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.1 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587) kidney smooth muscle tissue development(GO:0072194)
0.0 0.1 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536) regulation of respiratory burst involved in inflammatory response(GO:0060264) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.0 GO:2000137 negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137)
0.0 0.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.2 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.3 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.1 GO:0035261 external genitalia morphogenesis(GO:0035261)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.1 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.1 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) transformation of host cell by virus(GO:0019087) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.1 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.0 GO:1904247 regulation of polynucleotide adenylyltransferase activity(GO:1904245) positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.1 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.5 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.2 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.3 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.3 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.0 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.0 0.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.0 GO:0002588 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.0 0.0 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.1 GO:0042335 cuticle development(GO:0042335)
0.0 0.0 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.0 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.1 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.0 GO:0072179 regulation of pronephros size(GO:0035565) pronephric nephron tubule development(GO:0039020) nephric duct formation(GO:0072179) mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212)
0.0 0.0 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.1 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.4 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.0 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.0 GO:0005584 collagen type I trimer(GO:0005584)
0.0 0.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.1 0.2 GO:0004766 spermidine synthase activity(GO:0004766)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.1 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.1 GO:0097001 ceramide binding(GO:0097001)
0.0 0.0 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.1 GO:0048763 HLH domain binding(GO:0043398) calcium-induced calcium release activity(GO:0048763)
0.0 0.3 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.0 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.0 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.0 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.0 GO:0031433 telethonin binding(GO:0031433)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.3 PID S1P S1P4 PATHWAY S1P4 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway