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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for MYF6
Z-value: 1.08
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Transcription factors associated with MYF6
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| MYF6 | hg19_v2_chr12_+_81101277_81101321 | -0.69 | 1.3e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of MYF6
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | GO:0002076 | osteoblast development(GO:0002076) |
| 0.2 | 1.1 | GO:1902462 | regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462) |
| 0.0 | 1.1 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.1 | 0.9 | GO:0034465 | response to carbon monoxide(GO:0034465) |
| 0.0 | 0.8 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
| 0.0 | 0.7 | GO:0070257 | positive regulation of mucus secretion(GO:0070257) |
| 0.0 | 0.7 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.1 | 0.6 | GO:0036378 | calcitriol biosynthetic process from calciol(GO:0036378) |
| 0.1 | 0.6 | GO:0044805 | late nucleophagy(GO:0044805) |
| 0.0 | 0.6 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.1 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.1 | 0.6 | GO:0043260 | laminin-11 complex(GO:0043260) |
| 0.0 | 0.6 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
| 0.1 | 0.5 | GO:0016011 | dystroglycan complex(GO:0016011) |
| 0.0 | 0.5 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 0.0 | 0.5 | GO:0016471 | vacuolar proton-transporting V-type ATPase complex(GO:0016471) |
| 0.0 | 0.4 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.0 | 0.4 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.1 | 0.3 | GO:0070931 | Golgi-associated vesicle lumen(GO:0070931) |
| 0.0 | 0.3 | GO:1990357 | terminal web(GO:1990357) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 1.3 | GO:0001087 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.0 | 1.2 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.0 | 1.1 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.1 | 0.9 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.1 | 0.9 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
| 0.1 | 0.8 | GO:0018479 | benzaldehyde dehydrogenase (NAD+) activity(GO:0018479) |
| 0.1 | 0.7 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 0.0 | 0.7 | GO:0039706 | co-receptor binding(GO:0039706) |
| 0.0 | 0.7 | GO:0042043 | neurexin family protein binding(GO:0042043) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 1.5 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.0 | 1.3 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 0.2 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
| 0.0 | 0.2 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 0.7 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.0 | 0.6 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.0 | 0.6 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.5 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.0 | 0.5 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.0 | 0.5 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.0 | 0.4 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.0 | 0.3 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.0 | 0.3 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |