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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MNT_HEY1_HEY2

Z-value: 0.77

Motif logo

Transcription factors associated with MNT_HEY1_HEY2

Gene Symbol Gene ID Gene Info
ENSG00000070444.10 MAX network transcriptional repressor
ENSG00000164683.12 hes related family bHLH transcription factor with YRPW motif 1
ENSG00000135547.4 hes related family bHLH transcription factor with YRPW motif 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MNThg19_v2_chr17_-_2304365_2304412-0.681.4e-01Click!
HEY1hg19_v2_chr8_-_80680078_80680101-0.513.0e-01Click!
HEY2hg19_v2_chr6_+_126070726_126070768-0.295.8e-01Click!

Activity profile of MNT_HEY1_HEY2 motif

Sorted Z-values of MNT_HEY1_HEY2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_58145889 2.50 ENST00000547853.1
cyclin-dependent kinase 4
chr12_+_112451222 0.84 ENST00000552052.1
endoplasmic reticulum protein 29
chr8_+_104383759 0.61 ENST00000415886.2
collagen triple helix repeat containing 1
chr6_+_138188351 0.57 ENST00000421450.1
tumor necrosis factor, alpha-induced protein 3
chr3_-_53080644 0.57 ENST00000497586.1
Scm-like with four mbt domains 1
chr9_+_96928516 0.57 ENST00000602703.1
RP11-2B6.3
chr1_-_26232951 0.51 ENST00000426559.2
ENST00000455785.2
stathmin 1
chr17_-_6915616 0.50 ENST00000575889.1
Uncharacterized protein
chr1_+_154193325 0.49 ENST00000428931.1
ENST00000441890.1
ENST00000271877.7
ENST00000412596.1
ENST00000368504.1
ENST00000437652.1
ubiquitin associated protein 2-like
chr13_+_27998681 0.48 ENST00000381140.4
general transcription factor IIIA
chr2_-_232328867 0.44 ENST00000453992.1
ENST00000417652.1
ENST00000454824.1
nucleolin
chr20_+_2633269 0.43 ENST00000445139.1
NOP56 ribonucleoprotein
chr1_-_26233423 0.40 ENST00000357865.2
stathmin 1
chr11_-_61560053 0.38 ENST00000537328.1
transmembrane protein 258
chr1_-_26232522 0.38 ENST00000399728.1
stathmin 1
chr4_+_76439649 0.37 ENST00000507557.1
THAP domain containing 6
chr12_-_58146048 0.37 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
cyclin-dependent kinase 4
chr9_-_135545380 0.36 ENST00000544003.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr12_-_49318715 0.36 ENST00000444214.2
FK506 binding protein 11, 19 kDa
chr10_+_104474353 0.35 ENST00000602647.1
ENST00000602439.1
ENST00000602764.1
sideroflexin 2
chr1_-_11865982 0.34 ENST00000418034.1
methylenetetrahydrofolate reductase (NAD(P)H)
chr3_+_52719936 0.34 ENST00000418458.1
ENST00000394799.2
guanine nucleotide binding protein-like 3 (nucleolar)
chr1_+_150254936 0.34 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
chromosome 1 open reading frame 51
chr2_+_198365095 0.33 ENST00000409468.1
heat shock 10kDa protein 1
chr5_-_110074603 0.33 ENST00000515278.2
transmembrane protein 232
chr1_+_154193643 0.33 ENST00000456325.1
ubiquitin associated protein 2-like
chr8_+_104383728 0.32 ENST00000330295.5
collagen triple helix repeat containing 1
chr9_+_129987488 0.32 ENST00000446764.1
GTPase activating Rap/RanGAP domain-like 3
chr3_-_52719546 0.32 ENST00000439181.1
ENST00000449505.1
polybromo 1
chr12_-_58146128 0.30 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
cyclin-dependent kinase 4
chr6_-_39197226 0.30 ENST00000359534.3
potassium channel, subfamily K, member 5
chr7_-_150020216 0.30 ENST00000477367.1
ARP3 actin-related protein 3 homolog C (yeast)
chr11_-_2292182 0.30 ENST00000331289.4
achaete-scute family bHLH transcription factor 2
chr5_-_133706695 0.29 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
cyclin-dependent kinase-like 3
chr15_-_83316254 0.29 ENST00000567678.1
ENST00000450751.2
cytoplasmic polyadenylation element binding protein 1
chr15_+_44084503 0.29 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
small EDRK-rich factor 2
chr2_+_192543153 0.29 ENST00000425611.2
nucleic acid binding protein 1
chr11_+_777562 0.28 ENST00000530083.1
Protein LOC100506518
chr2_+_88991162 0.27 ENST00000283646.4
ribose 5-phosphate isomerase A
chr6_+_73331918 0.27 ENST00000402622.2
ENST00000355635.3
ENST00000403813.2
ENST00000414165.2
potassium voltage-gated channel, KQT-like subfamily, member 5
chr1_-_94344686 0.27 ENST00000528680.1
deoxynucleotidyltransferase, terminal, interacting protein 2
chr3_+_133292851 0.27 ENST00000503932.1
CDV3 homolog (mouse)
chr3_+_119187785 0.27 ENST00000295588.4
ENST00000476573.1
protein O-glucosyltransferase 1
chr16_-_18937072 0.27 ENST00000569122.1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr3_+_32148106 0.26 ENST00000425459.1
ENST00000431009.1
glycerol-3-phosphate dehydrogenase 1-like
chr3_-_52719888 0.26 ENST00000458294.1
polybromo 1
chr6_-_10694766 0.26 ENST00000460742.2
ENST00000259983.3
ENST00000379586.1
chromosome 6 open reading frame 52
chr2_-_10588630 0.26 ENST00000234111.4
ornithine decarboxylase 1
chr17_-_17109579 0.26 ENST00000321560.3
phospholipase D family, member 6
chr5_-_1799965 0.26 ENST00000508987.1
mitochondrial ribosomal protein L36
chrX_+_55744228 0.26 ENST00000262850.7
Ras-related GTP binding B
chr5_-_1799932 0.26 ENST00000382647.7
ENST00000505059.2
mitochondrial ribosomal protein L36
chr17_-_48450534 0.25 ENST00000503633.1
ENST00000442592.3
ENST00000225969.4
mitochondrial ribosomal protein L27
chr3_-_52719810 0.25 ENST00000424867.1
ENST00000394830.3
ENST00000431678.1
ENST00000450271.1
polybromo 1
chr13_-_103451307 0.25 ENST00000376004.4
KDEL (Lys-Asp-Glu-Leu) containing 1
chr17_+_46970127 0.23 ENST00000355938.5
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr15_-_72668185 0.23 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
hexosaminidase A (alpha polypeptide)
chr7_+_116593292 0.22 ENST00000393446.2
ENST00000265437.5
ENST00000393451.3
suppression of tumorigenicity 7
chr6_+_32936942 0.22 ENST00000496118.2
bromodomain containing 2
chr9_+_91926103 0.21 ENST00000314355.6
CDC28 protein kinase regulatory subunit 2
chr10_-_16859361 0.21 ENST00000377921.3
Ras suppressor protein 1
chr2_-_220042825 0.21 ENST00000409789.1
cyclin Pas1/PHO80 domain containing 1
chr1_-_11866034 0.21 ENST00000376590.3
methylenetetrahydrofolate reductase (NAD(P)H)
chr18_+_44497455 0.21 ENST00000592005.1
katanin p60 subunit A-like 2
chr17_+_48450575 0.21 ENST00000338165.4
ENST00000393271.2
ENST00000511519.2
essential meiotic structure-specific endonuclease 1
chr22_-_29663690 0.21 ENST00000406335.1
rhomboid domain containing 3
chr10_+_51827648 0.20 ENST00000351071.6
ENST00000314664.7
ENST00000282633.5
family with sequence similarity 21, member A
chrX_+_23685653 0.20 ENST00000379331.3
peroxiredoxin 4
chr9_+_130890612 0.20 ENST00000443493.1
AL590708.2
chr7_+_116593433 0.20 ENST00000323984.3
ENST00000393449.1
suppression of tumorigenicity 7
chr5_+_65440032 0.20 ENST00000334121.6
splicing regulatory glutamine/lysine-rich protein 1
chr17_-_27053216 0.20 ENST00000292090.3
TLC domain containing 1
chr5_+_176730769 0.20 ENST00000303204.4
ENST00000503216.1
PRELI domain containing 1
chr14_-_65569244 0.20 ENST00000557277.1
ENST00000556892.1
MYC associated factor X
chr8_-_95908902 0.20 ENST00000520509.1
cyclin E2
chr18_-_33077556 0.20 ENST00000589273.1
ENST00000586489.1
INO80 complex subunit C
chr17_+_46970134 0.20 ENST00000503641.1
ENST00000514808.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr17_+_7476136 0.20 ENST00000582169.1
ENST00000578754.1
ENST00000578495.1
ENST00000293831.8
ENST00000380512.5
ENST00000585024.1
ENST00000583802.1
ENST00000577269.1
ENST00000584784.1
ENST00000582746.1
eukaryotic translation initiation factor 4A1
chr17_-_42277203 0.19 ENST00000587097.1
ataxin 7-like 3
chr16_+_72042487 0.19 ENST00000572887.1
ENST00000219240.4
ENST00000574309.1
ENST00000576145.1
dihydroorotate dehydrogenase (quinone)
chrX_+_54556633 0.19 ENST00000336470.4
ENST00000360845.2
guanine nucleotide binding protein-like 3 (nucleolar)-like
chr12_-_123717711 0.19 ENST00000537854.1
M-phase phosphoprotein 9
chr1_+_45140400 0.19 ENST00000453711.1
chromosome 1 open reading frame 228
chr22_-_31741757 0.19 ENST00000215919.3
POZ (BTB) and AT hook containing zinc finger 1
chr14_-_91884150 0.19 ENST00000553403.1
coiled-coil domain containing 88C
chr10_-_44070016 0.19 ENST00000374446.2
ENST00000426961.1
ENST00000535642.1
zinc finger protein 239
chr1_+_1167594 0.19 ENST00000379198.2
UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
chr12_+_95611569 0.18 ENST00000261219.6
ENST00000551472.1
ENST00000552821.1
vezatin, adherens junctions transmembrane protein
chr6_+_7727030 0.18 ENST00000283147.6
bone morphogenetic protein 6
chr19_-_47734448 0.18 ENST00000439096.2
BCL2 binding component 3
chr7_-_155089251 0.18 ENST00000609974.1
AC144652.1
chrX_-_100662881 0.18 ENST00000218516.3
galactosidase, alpha
chr20_+_18118486 0.18 ENST00000432901.3
PET117 homolog (S. cerevisiae)
chr4_+_128651530 0.18 ENST00000281154.4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr2_+_27309605 0.18 ENST00000260599.6
ENST00000260598.5
ENST00000429697.1
ketohexokinase (fructokinase)
chr9_-_37904084 0.18 ENST00000377716.2
ENST00000242275.6
solute carrier family 25, member 51
chr17_-_32906388 0.18 ENST00000357754.1
chromosome 17 open reading frame 102
chr2_+_207024306 0.18 ENST00000236957.5
ENST00000392221.1
ENST00000392222.2
ENST00000445505.1
eukaryotic translation elongation factor 1 beta 2
chr7_+_44836276 0.18 ENST00000451562.1
ENST00000468812.1
ENST00000489459.1
ENST00000355968.6
peptidylprolyl isomerase A (cyclophilin A)
chr17_+_27052892 0.18 ENST00000579671.1
ENST00000579060.1
NIMA-related kinase 8
chr17_+_35306175 0.18 ENST00000225402.5
apoptosis antagonizing transcription factor
chr10_+_26986582 0.17 ENST00000376215.5
ENST00000376203.5
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr12_+_131356582 0.17 ENST00000448750.3
ENST00000541630.1
ENST00000392369.2
ENST00000254675.3
ENST00000535090.1
ENST00000392367.3
RAN, member RAS oncogene family
chr4_+_83351715 0.17 ENST00000273920.3
enolase-phosphatase 1
chr8_+_71581565 0.17 ENST00000408926.3
ENST00000520030.1
XK, Kell blood group complex subunit-related family, member 9
chr17_-_47492164 0.17 ENST00000512041.2
ENST00000446735.1
ENST00000504124.1
prohibitin
chr14_-_81687575 0.17 ENST00000434192.2
general transcription factor IIA, 1, 19/37kDa
chr6_-_167369612 0.17 ENST00000507747.1
RP11-514O12.4
chr1_-_45672221 0.17 ENST00000359600.5
zinc finger, SWIM-type containing 5
chr12_+_54674482 0.17 ENST00000547708.1
ENST00000340913.6
ENST00000551702.1
ENST00000330752.8
ENST00000547276.1
heterogeneous nuclear ribonucleoprotein A1
chr7_+_72742162 0.17 ENST00000431982.2
FK506 binding protein 6, 36kDa
chr11_+_75479850 0.17 ENST00000376262.3
ENST00000604733.1
diacylglycerol O-acyltransferase 2
chr18_+_33877654 0.17 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
formin homology 2 domain containing 3
chr3_-_112280709 0.16 ENST00000402314.2
ENST00000283290.5
ENST00000492886.1
autophagy related 3
chr22_-_36903069 0.16 ENST00000216187.6
ENST00000423980.1
FAD-dependent oxidoreductase domain containing 2
chr16_-_54963026 0.16 ENST00000560208.1
ENST00000557792.1
colorectal neoplasia differentially expressed (non-protein coding)
chr7_-_47621229 0.16 ENST00000434451.1
tensin 3
chr1_-_154193009 0.16 ENST00000368518.1
ENST00000368519.1
ENST00000368521.5
chromosome 1 open reading frame 43
chr14_+_92789498 0.16 ENST00000531433.1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr12_-_9102224 0.16 ENST00000543845.1
ENST00000544245.1
mannose-6-phosphate receptor (cation dependent)
chr3_-_149688971 0.16 ENST00000498307.1
ENST00000489155.1
profilin 2
chr2_+_177053307 0.16 ENST00000331462.4
homeobox D1
chr9_+_133454943 0.16 ENST00000319725.9
far upstream element (FUSE) binding protein 3
chr6_+_151561506 0.16 ENST00000253332.1
A kinase (PRKA) anchor protein 12
chr9_+_6758024 0.16 ENST00000442236.2
lysine (K)-specific demethylase 4C
chr17_-_37886752 0.16 ENST00000577810.1
migration and invasion enhancer 1
chr1_+_11866207 0.16 ENST00000312413.6
ENST00000346436.6
chloride channel, voltage-sensitive 6
chr3_-_150481218 0.16 ENST00000482706.1
siah E3 ubiquitin protein ligase 2
chr17_+_5185552 0.16 ENST00000262477.6
ENST00000408982.2
ENST00000575991.1
ENST00000537505.1
ENST00000546142.2
rabaptin, RAB GTPase binding effector protein 1
chr2_+_10183651 0.16 ENST00000305883.1
Kruppel-like factor 11
chr9_-_127533582 0.16 ENST00000416460.2
nuclear receptor subfamily 6, group A, member 1
chrX_+_55744166 0.16 ENST00000374941.4
ENST00000414239.1
Ras-related GTP binding B
chr17_-_48450265 0.16 ENST00000507088.1
mitochondrial ribosomal protein L27
chr1_-_38218577 0.15 ENST00000540011.1
EPH receptor A10
chr1_-_43833628 0.15 ENST00000413844.2
ENST00000372458.3
ELOVL fatty acid elongase 1
chr5_+_43120985 0.15 ENST00000515326.1
zinc finger protein 131
chr22_+_24891210 0.15 ENST00000382760.2
ureidopropionase, beta
chr1_-_52521831 0.15 ENST00000371626.4
thioredoxin domain containing 12 (endoplasmic reticulum)
chr17_+_30813576 0.15 ENST00000313401.3
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr10_+_104474207 0.15 ENST00000602831.1
ENST00000369893.5
sideroflexin 2
chr5_-_176738883 0.15 ENST00000513169.1
ENST00000423571.2
ENST00000502529.1
ENST00000427908.2
MAX dimerization protein 3
chr6_+_31865552 0.15 ENST00000469372.1
ENST00000497706.1
complement component 2
chr2_+_216176761 0.15 ENST00000540518.1
ENST00000435675.1
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr3_+_186649133 0.15 ENST00000417392.1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr10_-_6019552 0.15 ENST00000379977.3
ENST00000397251.3
ENST00000397248.2
interleukin 15 receptor, alpha
chr6_+_33359582 0.15 ENST00000450504.1
kinesin family member C1
chr11_+_66115304 0.15 ENST00000531602.1
Uncharacterized protein
chr10_-_16859442 0.15 ENST00000602389.1
ENST00000345264.5
Ras suppressor protein 1
chr1_+_19578033 0.15 ENST00000330263.4
mRNA turnover 4 homolog (S. cerevisiae)
chr10_-_99258135 0.15 ENST00000327238.10
ENST00000327277.7
ENST00000355839.6
ENST00000437002.1
ENST00000422685.1
MMS19 nucleotide excision repair homolog (S. cerevisiae)
chr22_+_18593097 0.15 ENST00000426208.1
tubulin, alpha 8
chr19_+_4402659 0.14 ENST00000301280.5
ENST00000585854.1
chromatin assembly factor 1, subunit A (p150)
chr20_+_42839600 0.14 ENST00000439943.1
ENST00000437730.1
OSER1 antisense RNA 1 (head to head)
chr15_-_82555000 0.14 ENST00000557844.1
ENST00000359445.3
ENST00000268206.7
elongation factor Tu GTP binding domain containing 1
chr6_-_114292284 0.14 ENST00000520895.1
ENST00000521163.1
ENST00000524334.1
ENST00000368632.2
ENST00000398283.2
histone deacetylase 2
chr19_+_19516561 0.14 ENST00000457895.2
GATA zinc finger domain containing 2A
chr1_+_45140360 0.14 ENST00000418644.1
ENST00000458657.2
ENST00000441519.1
ENST00000535358.1
ENST00000445071.1
chromosome 1 open reading frame 228
chr4_-_53522703 0.14 ENST00000508499.1
ubiquitin specific peptidase 46
chr9_+_6757634 0.14 ENST00000543771.1
ENST00000401787.3
ENST00000381306.3
ENST00000381309.3
lysine (K)-specific demethylase 4C
chr17_+_46970178 0.14 ENST00000393366.2
ENST00000506855.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr18_+_12948000 0.14 ENST00000585730.1
ENST00000399892.2
ENST00000589446.1
ENST00000587761.1
SEH1-like (S. cerevisiae)
chr18_+_12947981 0.14 ENST00000262124.11
SEH1-like (S. cerevisiae)
chr16_+_29467127 0.14 ENST00000344620.6
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr4_-_5891918 0.14 ENST00000512574.1
collapsin response mediator protein 1
chr10_+_46222648 0.14 ENST00000336378.4
ENST00000540872.1
ENST00000537517.1
ENST00000374362.2
ENST00000359860.4
ENST00000420848.1
family with sequence similarity 21, member C
chr2_+_86116396 0.14 ENST00000455121.3
AC105053.4
chr22_+_27068766 0.14 ENST00000435162.1
ENST00000437071.1
ENST00000440816.1
ENST00000421253.1
CTA-211A9.5
chr3_-_170626418 0.14 ENST00000474096.1
ENST00000295822.2
eukaryotic translation initiation factor 5A2
chr6_+_160390102 0.14 ENST00000356956.1
insulin-like growth factor 2 receptor
chr3_+_186648507 0.14 ENST00000458216.1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr7_+_2393714 0.14 ENST00000431643.1
eukaryotic translation initiation factor 3, subunit B
chr17_+_17876127 0.14 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
leucine rich repeat containing 48
chr15_+_32322685 0.14 ENST00000454250.3
ENST00000306901.3
cholinergic receptor, nicotinic, alpha 7 (neuronal)
chr2_+_74212073 0.14 ENST00000441217.1
AC073046.25
chr8_+_95907993 0.14 ENST00000523378.1
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr6_-_153304697 0.13 ENST00000367241.3
F-box protein 5
chr11_+_18343800 0.13 ENST00000453096.2
general transcription factor IIH, polypeptide 1, 62kDa
chr21_-_40720995 0.13 ENST00000380749.5
high mobility group nucleosome binding domain 1
chr1_+_11333546 0.13 ENST00000376804.2
UbiA prenyltransferase domain containing 1
chr5_-_122759032 0.13 ENST00000510582.3
ENST00000328236.5
ENST00000306481.6
ENST00000508442.2
ENST00000395431.2
centrosomal protein 120kDa
chr11_-_126081532 0.13 ENST00000533628.1
ENST00000298317.4
ENST00000532674.1
RNA pseudouridylate synthase domain containing 4
chr2_+_192542879 0.13 ENST00000409510.1
nucleic acid binding protein 1
chr1_-_212873267 0.13 ENST00000243440.1
basic leucine zipper transcription factor, ATF-like 3
chrX_-_128977875 0.13 ENST00000406492.2
zinc finger, DHHC-type containing 9
chr19_+_1407733 0.13 ENST00000592453.1
DAZ associated protein 1
chr11_+_126081662 0.13 ENST00000528985.1
ENST00000529731.1
ENST00000360194.4
ENST00000530043.1
family with sequence similarity 118, member B
chr18_-_21977748 0.13 ENST00000399441.4
ENST00000319481.3
oxysterol binding protein-like 1A
chr9_+_34646651 0.13 ENST00000378842.3
galactose-1-phosphate uridylyltransferase
chr19_-_14201507 0.13 ENST00000533683.2
sterile alpha motif domain containing 1
chr2_-_232329186 0.13 ENST00000322723.4
nucleolin
chrX_+_134124968 0.13 ENST00000330288.4
small integral membrane protein 10
chr7_+_116593568 0.13 ENST00000446490.1
suppression of tumorigenicity 7
chr20_-_44519839 0.13 ENST00000372518.4
neuralized E3 ubiquitin protein ligase 2
chr1_+_109656579 0.13 ENST00000526264.1
ENST00000369939.3
KIAA1324
chr12_+_130822606 0.13 ENST00000546060.1
ENST00000539400.1
piwi-like RNA-mediated gene silencing 1
chr5_+_151151504 0.13 ENST00000356245.3
ENST00000507878.2
GTPase activating protein (SH3 domain) binding protein 1
chr17_+_76311791 0.13 ENST00000586321.1
AC061992.2
chr12_+_122356488 0.13 ENST00000397454.2
WD repeat domain 66
chr6_-_105584560 0.13 ENST00000336775.5
blood vessel epicardial substance
chr5_+_112227311 0.13 ENST00000391338.1
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1

Network of associatons between targets according to the STRING database.

First level regulatory network of MNT_HEY1_HEY2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.2 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.3 0.8 GO:0090291 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of osteoclast proliferation(GO:0090291) negative regulation of CD40 signaling pathway(GO:2000349)
0.2 1.4 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.2 0.9 GO:0043335 protein unfolding(GO:0043335)
0.1 0.9 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.9 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.6 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.3 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.1 0.2 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.1 0.2 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.1 0.2 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.1 0.3 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.1 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.3 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 0.2 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.1 0.2 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.1 0.4 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 0.2 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.1 0.3 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.1 0.2 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.4 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.7 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.6 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.2 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.1 GO:0048041 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)
0.0 0.1 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.3 GO:0006014 D-ribose metabolic process(GO:0006014) pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.2 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.2 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.2 GO:1903936 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 0.1 GO:0060931 sinoatrial node cell development(GO:0060931)
0.0 0.2 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.2 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.2 GO:0009233 menaquinone metabolic process(GO:0009233)
0.0 0.2 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.0 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.1 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.0 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.2 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.0 0.2 GO:0051029 rRNA transport(GO:0051029)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.1 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.1 GO:0002368 B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.2 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.1 GO:0072720 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.0 0.1 GO:0003420 growth plate cartilage chondrocyte proliferation(GO:0003419) regulation of growth plate cartilage chondrocyte proliferation(GO:0003420)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.2 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.2 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.3 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.6 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.0 0.1 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.1 GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 0.1 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.1 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.1 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.1 GO:0000966 RNA 5'-end processing(GO:0000966)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.1 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.1 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.0 0.3 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.2 GO:0072553 terminal button organization(GO:0072553)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.2 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.0 GO:0001508 action potential(GO:0001508)
0.0 0.0 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0 0.1 GO:0051101 regulation of DNA binding(GO:0051101)
0.0 0.1 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.2 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685) operant conditioning(GO:0035106)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.1 GO:0035377 transepithelial water transport(GO:0035377) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.1 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.0 0.1 GO:2000051 Wnt receptor catabolic process(GO:0038018) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.2 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0 0.1 GO:1902024 histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.0 0.0 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.0 0.1 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.0 0.1 GO:0050893 sensory processing(GO:0050893)
0.0 0.0 GO:0031929 TOR signaling(GO:0031929) regulation of TOR signaling(GO:0032006)
0.0 0.0 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.0 GO:0072034 renal vesicle induction(GO:0072034)
0.0 0.1 GO:0015766 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.2 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.0 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.0 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.0 0.6 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:0048817 negative regulation of hair follicle maturation(GO:0048817)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.0 GO:2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.0 0.2 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.1 GO:0045575 basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.0 0.2 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.0 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.0 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.0 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.1 GO:0036071 N-glycan fucosylation(GO:0036071)
0.0 0.2 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.0 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.0 GO:0048145 regulation of fibroblast proliferation(GO:0048145) positive regulation of fibroblast proliferation(GO:0048146)
0.0 0.0 GO:0016180 snRNA processing(GO:0016180) snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.0 GO:0051006 positive regulation of lipoprotein lipase activity(GO:0051006)
0.0 0.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.1 GO:0038086 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.0 0.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0061724 lipophagy(GO:0061724) negative regulation of exosomal secretion(GO:1903542)
0.0 1.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.1 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.1 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.1 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.1 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.0 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.0 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.0 GO:0046963 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.0 0.1 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.0 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.0 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.0 0.0 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.0 GO:0001501 skeletal system development(GO:0001501)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.0 GO:0031106 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.0 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.0 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.0 0.0 GO:0042412 taurine biosynthetic process(GO:0042412)
0.0 0.0 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.0 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.1 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 0.1 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.0 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.0 GO:2000106 regulation of T cell apoptotic process(GO:0070232) regulation of leukocyte apoptotic process(GO:2000106)
0.0 0.0 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.0 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.1 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 0.1 GO:0032055 negative regulation of translation in response to stress(GO:0032055)
0.0 0.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.2 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 1.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.2 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.0 0.1 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.4 GO:0000154 rRNA modification(GO:0000154)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.0 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.0 0.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.0 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.2 GO:0042565 RNA nuclear export complex(GO:0042565)
0.1 0.4 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.5 GO:0070876 SOSS complex(GO:0070876)
0.1 0.2 GO:0097543 ciliary inversin compartment(GO:0097543)
0.1 0.2 GO:0043614 multi-eIF complex(GO:0043614)
0.0 0.2 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.1 GO:0009346 citrate lyase complex(GO:0009346)
0.0 1.0 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.6 GO:0000124 SAGA complex(GO:0000124)
0.0 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.0 GO:0034448 EGO complex(GO:0034448)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.4 GO:0033391 chromatoid body(GO:0033391)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0005694 chromosome(GO:0005694)
0.0 0.9 GO:0090544 BAF-type complex(GO:0090544)
0.0 1.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:0030689 Noc complex(GO:0030689)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0031674 I band(GO:0031674)
0.0 0.8 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.0 GO:0019034 viral replication complex(GO:0019034)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0005606 laminin-1 complex(GO:0005606) laminin-11 complex(GO:0043260)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 1.1 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.3 GO:0097227 sperm annulus(GO:0097227)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.0 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.1 GO:0035838 growing cell tip(GO:0035838)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.0 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.0 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0001673 male germ cell nucleus(GO:0001673)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.3 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.3 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 0.2 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.1 0.6 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 0.2 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.1 3.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.2 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 0.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 0.2 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.1 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.3 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.1 GO:0003878 ATP citrate synthase activity(GO:0003878)
0.0 0.1 GO:0030984 kininogen binding(GO:0030984)
0.0 0.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.3 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.1 GO:0005055 laminin receptor activity(GO:0005055)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.2 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.2 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.1 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.0 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.2 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.2 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.8 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.1 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0017130 poly(C) RNA binding(GO:0017130)
0.0 0.1 GO:0004766 spermidine synthase activity(GO:0004766)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.1 GO:0008841 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.1 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.2 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.0 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.0 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.0 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.0 0.1 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.0 0.0 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.0 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.3 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.0 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.0 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.0 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.0 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.0 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.2 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.0 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.0 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.4 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 1.1 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.0 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.1 GO:0031386 protein tag(GO:0031386)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.0 GO:0019828 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.0 0.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.9 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.7 PID MYC PATHWAY C-MYC pathway
0.0 0.1 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 3.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.6 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.0 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.1 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.2 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.2 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.2 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation