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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MIXL1_GSX1_BSX_MEOX2_LHX4

Z-value: 0.97

Motif logo

Transcription factors associated with MIXL1_GSX1_BSX_MEOX2_LHX4

Gene Symbol Gene ID Gene Info
ENSG00000185155.7 MIXL1
ENSG00000169840.4 GSX1
ENSG00000188909.4 BSX
ENSG00000106511.5 MEOX2
ENSG00000121454.4 LHX4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX4hg19_v2_chr1_+_180199393_1801994260.592.1e-01Click!
MIXL1hg19_v2_chr1_+_226411319_226411366-0.513.0e-01Click!

Activity profile of MIXL1_GSX1_BSX_MEOX2_LHX4 motif

Sorted Z-values of MIXL1_GSX1_BSX_MEOX2_LHX4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MIXL1_GSX1_BSX_MEOX2_LHX4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_-_77427676 1.27 ENST00000257663.3
TMEM60
transmembrane protein 60
chr4_-_36245561 1.21 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr3_-_143567262 1.12 ENST00000474151.1
ENST00000316549.6
SLC9A9
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr2_+_17997763 1.11 ENST00000281047.3
MSGN1
mesogenin 1
chr5_-_24645078 0.96 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr16_+_53412368 0.93 ENST00000565189.1
RP11-44F14.2
RP11-44F14.2
chr1_+_62439037 0.93 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr13_-_86373536 0.84 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr5_+_136070614 0.81 ENST00000502421.1
CTB-1I21.1
CTB-1I21.1
chrX_+_22050546 0.76 ENST00000379374.4
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr9_-_3469181 0.73 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr6_+_76330355 0.72 ENST00000483859.2
SENP6
SUMO1/sentrin specific peptidase 6
chr7_+_77428066 0.71 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
PHTF2
putative homeodomain transcription factor 2
chr12_+_28410128 0.67 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr19_-_56110859 0.66 ENST00000221665.3
ENST00000592585.1
FIZ1
FLT3-interacting zinc finger 1
chr5_+_102200948 0.64 ENST00000511477.1
ENST00000506006.1
ENST00000509832.1
PAM
peptidylglycine alpha-amidating monooxygenase
chr2_+_149402989 0.62 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chrX_+_123097014 0.62 ENST00000394478.1
STAG2
stromal antigen 2
chr13_-_38172863 0.62 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN
periostin, osteoblast specific factor
chr2_-_188312971 0.62 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
CALCRL
calcitonin receptor-like
chr5_+_115177178 0.60 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr5_-_148929848 0.59 ENST00000504676.1
ENST00000515435.1
CSNK1A1
casein kinase 1, alpha 1
chr7_+_77428149 0.59 ENST00000415251.2
ENST00000275575.7
PHTF2
putative homeodomain transcription factor 2
chr3_-_108248169 0.59 ENST00000273353.3
MYH15
myosin, heavy chain 15
chr10_-_115904361 0.58 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chr1_-_101360205 0.57 ENST00000450240.1
EXTL2
exostosin-like glycosyltransferase 2
chr16_+_53133070 0.57 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr1_-_101360331 0.56 ENST00000416479.1
ENST00000370113.3
EXTL2
exostosin-like glycosyltransferase 2
chr7_-_99716914 0.56 ENST00000431404.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr8_+_92114873 0.52 ENST00000343709.3
ENST00000448384.2
LRRC69
leucine rich repeat containing 69
chr4_+_146402346 0.52 ENST00000514778.1
ENST00000507594.1
SMAD1
SMAD family member 1
chr18_-_33709268 0.51 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr7_-_83278322 0.51 ENST00000307792.3
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr11_-_111649074 0.51 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr12_+_25205155 0.50 ENST00000550945.1
LRMP
lymphoid-restricted membrane protein
chr3_+_121774202 0.47 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr7_-_84122033 0.47 ENST00000424555.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr5_+_68860949 0.47 ENST00000507595.1
GTF2H2C
general transcription factor IIH, polypeptide 2C
chr5_+_174151536 0.47 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chr13_+_110958124 0.46 ENST00000400163.2
COL4A2
collagen, type IV, alpha 2
chr8_+_22424551 0.46 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chr10_+_94451574 0.45 ENST00000492654.2
HHEX
hematopoietically expressed homeobox
chr2_+_190541153 0.45 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ANKAR
ankyrin and armadillo repeat containing
chr17_+_48823975 0.44 ENST00000513969.1
ENST00000503728.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr17_+_61151306 0.44 ENST00000580068.1
ENST00000580466.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr10_-_105110890 0.42 ENST00000369847.3
PCGF6
polycomb group ring finger 6
chr3_-_151034734 0.41 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr2_-_136678123 0.40 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr1_-_168464875 0.39 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr4_+_169013666 0.39 ENST00000359299.3
ANXA10
annexin A10
chr1_-_48866517 0.38 ENST00000371841.1
SPATA6
spermatogenesis associated 6
chr6_+_127898312 0.37 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr8_-_90996459 0.36 ENST00000517337.1
ENST00000409330.1
NBN
nibrin
chr11_-_26593779 0.36 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr11_-_111794446 0.36 ENST00000527950.1
CRYAB
crystallin, alpha B
chr2_-_61697862 0.35 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr12_+_41136144 0.35 ENST00000548005.1
ENST00000552248.1
CNTN1
contactin 1
chr14_+_39944025 0.34 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
RP11-111A21.1
chr6_-_109702885 0.34 ENST00000504373.1
CD164
CD164 molecule, sialomucin
chr16_-_29910853 0.34 ENST00000308713.5
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr6_-_56492816 0.34 ENST00000522360.1
DST
dystonin
chr6_+_26087509 0.34 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
HFE
hemochromatosis
chr2_-_203735586 0.33 ENST00000454326.1
ENST00000432273.1
ENST00000450143.1
ENST00000411681.1
ICA1L
islet cell autoantigen 1,69kDa-like
chr4_+_183065793 0.33 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chrX_-_55208866 0.33 ENST00000545075.1
MTRNR2L10
MT-RNR2-like 10
chr2_-_214016314 0.33 ENST00000434687.1
ENST00000374319.4
IKZF2
IKAROS family zinc finger 2 (Helios)
chr19_+_11457175 0.32 ENST00000458408.1
ENST00000586451.1
ENST00000588592.1
CCDC159
coiled-coil domain containing 159
chr1_-_152131703 0.32 ENST00000316073.3
RPTN
repetin
chr17_+_72427477 0.32 ENST00000342648.5
ENST00000481232.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr1_-_101360374 0.32 ENST00000535414.1
EXTL2
exostosin-like glycosyltransferase 2
chr12_+_21207503 0.32 ENST00000545916.1
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr7_-_35013217 0.32 ENST00000446375.1
DPY19L1
dpy-19-like 1 (C. elegans)
chr15_+_96904487 0.31 ENST00000600790.1
AC087477.1
Uncharacterized protein
chr5_-_126409159 0.31 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
C5orf63
chromosome 5 open reading frame 63
chr2_-_17981462 0.31 ENST00000402989.1
ENST00000428868.1
SMC6
structural maintenance of chromosomes 6
chr16_-_66864806 0.31 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
NAE1
NEDD8 activating enzyme E1 subunit 1
chr11_-_94965667 0.31 ENST00000542176.1
ENST00000278499.2
SESN3
sestrin 3
chr9_-_131486367 0.31 ENST00000372663.4
ENST00000406904.2
ENST00000452105.1
ENST00000372672.2
ENST00000372667.5
ZDHHC12
zinc finger, DHHC-type containing 12
chr10_-_28571015 0.30 ENST00000375719.3
ENST00000375732.1
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr6_+_55192267 0.30 ENST00000340465.2
GFRAL
GDNF family receptor alpha like
chr1_+_152784447 0.30 ENST00000360090.3
LCE1B
late cornified envelope 1B
chr8_-_17533838 0.30 ENST00000400046.1
MTUS1
microtubule associated tumor suppressor 1
chr8_-_102803163 0.30 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD
neurocalcin delta
chr12_+_122688090 0.29 ENST00000324189.4
ENST00000546192.1
B3GNT4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr12_+_44229846 0.29 ENST00000551577.1
ENST00000266534.3
TMEM117
transmembrane protein 117
chr19_+_50016610 0.29 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr4_+_159727272 0.28 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr1_+_117963209 0.28 ENST00000449370.2
MAN1A2
mannosidase, alpha, class 1A, member 2
chr7_+_99425633 0.28 ENST00000354829.2
ENST00000421837.2
ENST00000417625.1
ENST00000342499.4
ENST00000444905.1
ENST00000415413.1
ENST00000312017.5
ENST00000222382.5
CYP3A43
cytochrome P450, family 3, subfamily A, polypeptide 43
chr8_-_27469196 0.28 ENST00000546343.1
ENST00000560566.1
CLU
clusterin
chr11_-_104972158 0.28 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr12_-_88974236 0.28 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG
KIT ligand
chr18_+_29027696 0.28 ENST00000257189.4
DSG3
desmoglein 3
chr5_-_142780280 0.28 ENST00000424646.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr7_-_99717463 0.28 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr14_-_51027838 0.27 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr16_-_3350614 0.27 ENST00000268674.2
TIGD7
tigger transposable element derived 7
chr4_+_104346194 0.26 ENST00000510200.1
RP11-328K4.1
RP11-328K4.1
chrX_+_37865804 0.26 ENST00000297875.2
ENST00000357972.5
SYTL5
synaptotagmin-like 5
chr2_-_190446738 0.26 ENST00000427419.1
ENST00000455320.1
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr10_-_105110831 0.26 ENST00000337211.4
PCGF6
polycomb group ring finger 6
chr12_-_46121554 0.26 ENST00000609803.1
LINC00938
long intergenic non-protein coding RNA 938
chr7_+_23286182 0.26 ENST00000258733.4
ENST00000381990.2
ENST00000409458.3
ENST00000539136.1
ENST00000453162.2
GPNMB
glycoprotein (transmembrane) nmb
chr5_+_81601166 0.26 ENST00000439350.1
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr19_+_48949087 0.25 ENST00000598711.1
GRWD1
glutamate-rich WD repeat containing 1
chr17_-_71223839 0.25 ENST00000579872.1
ENST00000580032.1
FAM104A
family with sequence similarity 104, member A
chr8_+_42873548 0.25 ENST00000533338.1
ENST00000534420.1
HOOK3
RP11-598P20.5
hook microtubule-tethering protein 3
Uncharacterized protein
chr3_+_186692745 0.25 ENST00000438590.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr4_+_90033968 0.25 ENST00000317005.2
TIGD2
tigger transposable element derived 2
chr6_-_111804905 0.25 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chrX_+_139791917 0.25 ENST00000607004.1
ENST00000370535.3
LINC00632
long intergenic non-protein coding RNA 632
chr12_-_52967600 0.25 ENST00000549343.1
ENST00000305620.2
KRT74
keratin 74
chr4_-_87028478 0.24 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chr2_+_109204909 0.24 ENST00000393310.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr3_-_33686925 0.24 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chr16_-_66764119 0.24 ENST00000569320.1
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr2_-_166702601 0.24 ENST00000428888.1
AC009495.4
AC009495.4
chr12_+_18414446 0.24 ENST00000433979.1
PIK3C2G
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
chr12_-_10282742 0.24 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A
C-type lectin domain family 7, member A
chr17_-_48133054 0.24 ENST00000499842.1
RP11-1094H24.4
RP11-1094H24.4
chr1_+_180601139 0.24 ENST00000367590.4
ENST00000367589.3
XPR1
xenotropic and polytropic retrovirus receptor 1
chr8_+_26150628 0.24 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr12_+_107712173 0.23 ENST00000280758.5
ENST00000420571.2
BTBD11
BTB (POZ) domain containing 11
chr5_+_140602904 0.23 ENST00000515856.2
ENST00000239449.4
PCDHB14
protocadherin beta 14
chr8_-_27468842 0.23 ENST00000523500.1
CLU
clusterin
chr6_-_121655850 0.23 ENST00000422369.1
TBC1D32
TBC1 domain family, member 32
chr8_-_112248400 0.23 ENST00000519506.1
ENST00000522778.1
RP11-946L20.4
RP11-946L20.4
chr8_-_27469383 0.23 ENST00000519742.1
CLU
clusterin
chr14_-_64194745 0.23 ENST00000247225.6
SGPP1
sphingosine-1-phosphate phosphatase 1
chrX_-_13835147 0.23 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr14_+_36295504 0.22 ENST00000216807.7
BRMS1L
breast cancer metastasis-suppressor 1-like
chr12_+_25205568 0.22 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr17_-_57229155 0.22 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr2_+_171034646 0.22 ENST00000409044.3
ENST00000408978.4
MYO3B
myosin IIIB
chr19_-_11457162 0.22 ENST00000590482.1
TMEM205
transmembrane protein 205
chr14_+_62462541 0.22 ENST00000430451.2
SYT16
synaptotagmin XVI
chr4_+_74576019 0.22 ENST00000436089.1
AC112518.3
AC112518.3
chr8_+_97773202 0.22 ENST00000519484.1
CPQ
carboxypeptidase Q
chr10_+_118349920 0.22 ENST00000531984.1
PNLIPRP1
pancreatic lipase-related protein 1
chr9_+_67977438 0.22 ENST00000456982.1
RP11-195B21.3
Protein LOC644249
chr1_+_210501589 0.22 ENST00000413764.2
ENST00000541565.1
HHAT
hedgehog acyltransferase
chr9_-_123639445 0.22 ENST00000312189.6
PHF19
PHD finger protein 19
chr18_+_21572737 0.22 ENST00000304621.6
TTC39C
tetratricopeptide repeat domain 39C
chr11_-_118023594 0.21 ENST00000529878.1
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
chr14_-_23652849 0.21 ENST00000316902.7
ENST00000469263.1
ENST00000525062.1
ENST00000524758.1
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr1_+_212475148 0.21 ENST00000537030.3
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr12_-_118796910 0.21 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr4_+_40198527 0.21 ENST00000381799.5
RHOH
ras homolog family member H
chr11_+_27076764 0.21 ENST00000525090.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr9_-_5830768 0.21 ENST00000381506.3
ERMP1
endoplasmic reticulum metallopeptidase 1
chr5_-_89770582 0.21 ENST00000316610.6
MBLAC2
metallo-beta-lactamase domain containing 2
chr1_+_78470530 0.21 ENST00000370763.5
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr11_+_121447469 0.21 ENST00000532694.1
ENST00000534286.1
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr14_+_57671888 0.21 ENST00000391612.1
AL391152.1
AL391152.1
chr19_-_44388116 0.21 ENST00000587539.1
ZNF404
zinc finger protein 404
chr12_+_19358228 0.20 ENST00000424268.1
ENST00000543806.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr8_-_124279627 0.20 ENST00000357082.4
ZHX1-C8ORF76
ZHX1-C8ORF76 readthrough
chr7_+_116502527 0.20 ENST00000361183.3
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr6_+_26365443 0.20 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2
butyrophilin, subfamily 3, member A2
chr6_-_75994025 0.20 ENST00000518161.1
TMEM30A
transmembrane protein 30A
chr8_-_42358742 0.20 ENST00000517366.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr2_-_99871570 0.20 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
LYG2
lysozyme G-like 2
chr16_-_4852915 0.20 ENST00000322048.7
ROGDI
rogdi homolog (Drosophila)
chr1_+_84609944 0.20 ENST00000370685.3
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr4_+_41614909 0.19 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chrX_+_95939638 0.19 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
DIAPH2
diaphanous-related formin 2
chr10_-_104866395 0.19 ENST00000458345.1
NT5C2
5'-nucleotidase, cytosolic II
chr18_+_32173276 0.19 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA
dystrobrevin, alpha
chrX_+_77166172 0.19 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr11_-_26593677 0.19 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chrX_+_13671225 0.19 ENST00000545566.1
ENST00000544987.1
ENST00000314720.4
TCEANC
transcription elongation factor A (SII) N-terminal and central domain containing
chr16_+_68279256 0.18 ENST00000564827.2
ENST00000566188.1
ENST00000444212.2
ENST00000568082.1
PLA2G15
phospholipase A2, group XV
chr1_+_219347203 0.18 ENST00000366927.3
LYPLAL1
lysophospholipase-like 1
chr6_-_52859046 0.18 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
GSTA4
glutathione S-transferase alpha 4
chr4_-_103749105 0.18 ENST00000394801.4
ENST00000394804.2
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr5_+_137673200 0.18 ENST00000434981.2
FAM53C
family with sequence similarity 53, member C
chr7_-_99716952 0.18 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr7_-_84121858 0.18 ENST00000448879.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr1_+_160370344 0.18 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr3_-_194188956 0.18 ENST00000256031.4
ENST00000446356.1
ATP13A3
ATPase type 13A3
chr18_+_57567180 0.18 ENST00000316660.6
ENST00000269518.9
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr3_-_98619999 0.18 ENST00000449482.1
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr4_+_144312659 0.18 ENST00000509992.1
GAB1
GRB2-associated binding protein 1
chr4_+_95916947 0.18 ENST00000506363.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr9_+_109685630 0.18 ENST00000451160.2
RP11-508N12.4
Uncharacterized protein
chr2_+_191221240 0.18 ENST00000409027.1
ENST00000458193.1
INPP1
inositol polyphosphate-1-phosphatase
chr1_-_68698197 0.18 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr7_-_14029283 0.18 ENST00000433547.1
ENST00000405192.2
ETV1
ets variant 1
chr8_-_102216925 0.18 ENST00000517844.1
ZNF706
zinc finger protein 706
chr1_-_234667504 0.18 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
RP5-855F14.1
chr5_+_137722255 0.18 ENST00000542866.1
KDM3B
lysine (K)-specific demethylase 3B
chr13_+_20268547 0.17 ENST00000601204.1
AL354808.2
AL354808.2
chr1_+_12042015 0.17 ENST00000412236.1
MFN2
mitofusin 2
chr21_+_25801041 0.17 ENST00000453784.2
ENST00000423581.1
AP000476.1
AP000476.1
chr2_-_109605663 0.17 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
EDAR
ectodysplasin A receptor
chrX_-_19988382 0.17 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
CXorf23
chromosome X open reading frame 23
chr4_+_86748898 0.17 ENST00000509300.1
ARHGAP24
Rho GTPase activating protein 24
chr2_+_183982255 0.17 ENST00000455063.1
NUP35
nucleoporin 35kDa
chr4_-_139163491 0.17 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr18_-_53019208 0.17 ENST00000562607.1
TCF4
transcription factor 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0034756 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759)
0.2 0.5 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.2 0.5 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.2 0.5 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.1 0.6 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.1 0.8 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.8 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 0.4 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 0.6 GO:0032571 response to vitamin K(GO:0032571)
0.1 1.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.4 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.4 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.6 GO:0018032 protein amidation(GO:0018032)
0.1 0.7 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 0.4 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.7 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.3 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1 0.3 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.5 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.3 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.2 GO:1902960 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.6 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 0.6 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 0.3 GO:0070839 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
0.1 0.2 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.3 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 1.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.2 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 0.2 GO:0035937 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.1 0.4 GO:0061458 reproductive system development(GO:0061458)
0.1 0.2 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.0 1.1 GO:0007379 segment specification(GO:0007379)
0.0 0.3 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.4 GO:0097338 response to clozapine(GO:0097338)
0.0 0.2 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.6 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.2 GO:0060577 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.0 0.3 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.3 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.4 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.5 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.7 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.1 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.2 GO:0009820 alkaloid metabolic process(GO:0009820)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700) regulation of penile erection(GO:0060405)
0.0 0.3 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.1 GO:0008057 eye pigment granule organization(GO:0008057)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.2 GO:2000691 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.1 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.0 0.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.1 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.0 0.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.2 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.3 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.3 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0002584 negative regulation of antigen processing and presentation of peptide antigen(GO:0002584)
0.0 0.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.3 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.2 GO:0043010 camera-type eye development(GO:0043010)
0.0 0.4 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.2 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.1 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.0 0.2 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.1 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.0 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:2001023 regulation of response to drug(GO:2001023)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.6 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.1 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.1 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.5 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.5 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.2 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.2 GO:0014820 tonic smooth muscle contraction(GO:0014820)
0.0 0.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:1900004 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.0 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.0 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.0 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 1.4 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.4 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.1 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.0 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 0.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.0 GO:0071440 regulation of histone H3-K14 acetylation(GO:0071440) positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.1 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.2 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.2 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.0 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.0 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.1 GO:1903286 regulation of potassium ion import(GO:1903286)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.1 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.6 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.0 GO:0045113 regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.0 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.0 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.1 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.2 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.1 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.0 0.0 GO:0030821 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.0 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.1 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.0 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 0.3 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.0 GO:0042335 cuticle development(GO:0042335)
0.0 0.1 GO:0040013 negative regulation of locomotion(GO:0040013)
0.0 0.1 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.2 GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307)
0.0 0.1 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.0 0.1 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.0 0.2 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0090269 fibroblast growth factor production(GO:0090269) regulation of fibroblast growth factor production(GO:0090270)
0.0 0.0 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.2 GO:0072643 interferon-gamma secretion(GO:0072643)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0097224 sperm connecting piece(GO:0097224)
0.1 0.7 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.4 GO:0097179 protease inhibitor complex(GO:0097179)
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.1 0.4 GO:1990357 terminal web(GO:1990357)
0.1 0.5 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.7 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.2 GO:0071547 piP-body(GO:0071547)
0.0 0.2 GO:0060187 cell pole(GO:0060187)
0.0 0.3 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.5 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.5 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.5 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.7 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.7 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.4 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.6 GO:0032982 myosin filament(GO:0032982)
0.0 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.5 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.7 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.3 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.5 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.0 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 0.1 GO:0097196 Shu complex(GO:0097196)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.0 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 1.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.4 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.2 0.6 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.4 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 0.6 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.8 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 1.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.4 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.3 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.3 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.2 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.1 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.4 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.2 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.1 0.6 GO:0032027 myosin light chain binding(GO:0032027)
0.0 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.0 0.9 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.4 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.7 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.2 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.3 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.2 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.1 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.0 0.3 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.0 0.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.6 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.4 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0016826 N-sulfoglucosamine sulfohydrolase activity(GO:0016250) hydrolase activity, acting on acid sulfur-nitrogen bonds(GO:0016826)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.7 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.4 GO:0070330 aromatase activity(GO:0070330)
0.0 0.1 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.4 GO:0043295 glutathione binding(GO:0043295)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.1 GO:0015265 glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.0 GO:0051393 actinin binding(GO:0042805) alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.0 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 1.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.8 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.5 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.0 GO:0004803 transposase activity(GO:0004803)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.4 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.6 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.8 PID BARD1 PATHWAY BARD1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.1 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.9 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport