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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MEF2C

Z-value: 0.61

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Transcription factors associated with MEF2C

Gene Symbol Gene ID Gene Info
MEF2C
ENSG00000081189.9 myocyte enhancer factor 2C

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MEF2Chg19_v2_chr5_-_88179302_88179319-0.621.9e-01Click!

Activity profile of MEF2C motif

Sorted Z-values of MEF2C motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_12108410 0.46 ENST00000527997.1
RP13-631K18.5
RP13-631K18.5
chr16_-_18923035 0.34 ENST00000563836.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr11_+_1860200 0.31 ENST00000381911.1
TNNI2
troponin I type 2 (skeletal, fast)
chr4_-_186696561 0.29 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
SORBS2
sorbin and SH3 domain containing 2
chr5_-_111091948 0.26 ENST00000447165.2
NREP
neuronal regeneration related protein
chr15_-_76352069 0.22 ENST00000305435.10
ENST00000563910.1
NRG4
neuregulin 4
chr13_-_45048386 0.22 ENST00000472477.1
TSC22D1
TSC22 domain family, member 1
chr8_-_72268721 0.21 ENST00000419131.1
ENST00000388743.2
EYA1
eyes absent homolog 1 (Drosophila)
chr11_+_1860682 0.20 ENST00000381906.1
TNNI2
troponin I type 2 (skeletal, fast)
chr8_-_17533838 0.20 ENST00000400046.1
MTUS1
microtubule associated tumor suppressor 1
chr7_+_75931861 0.20 ENST00000248553.6
HSPB1
heat shock 27kDa protein 1
chr8_+_107282389 0.19 ENST00000577661.1
ENST00000445937.1
RP11-395G23.3
OXR1
RP11-395G23.3
oxidation resistance 1
chr1_+_156095951 0.19 ENST00000448611.2
ENST00000368297.1
LMNA
lamin A/C
chr1_-_116383322 0.18 ENST00000429731.1
NHLH2
nescient helix loop helix 2
chr6_+_151358048 0.18 ENST00000450635.1
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chrX_+_123095860 0.18 ENST00000428941.1
STAG2
stromal antigen 2
chr13_+_97928395 0.18 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr3_+_193853927 0.18 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr21_+_35107346 0.17 ENST00000456489.1
ITSN1
intersectin 1 (SH3 domain protein)
chr17_-_27467418 0.16 ENST00000528564.1
MYO18A
myosin XVIIIA
chr3_+_8543561 0.16 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr15_+_100106155 0.16 ENST00000557785.1
ENST00000558049.1
ENST00000449277.2
MEF2A
myocyte enhancer factor 2A
chr11_+_65266507 0.15 ENST00000544868.1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr11_+_1860832 0.15 ENST00000252898.7
TNNI2
troponin I type 2 (skeletal, fast)
chr2_+_145780767 0.15 ENST00000599358.1
ENST00000596278.1
ENST00000596747.1
ENST00000608652.1
ENST00000609705.1
ENST00000608432.1
ENST00000596970.1
ENST00000602041.1
ENST00000601578.1
ENST00000596034.1
ENST00000414195.2
ENST00000594837.1
TEX41
testis expressed 41 (non-protein coding)
chr1_-_152131703 0.15 ENST00000316073.3
RPTN
repetin
chr3_-_121264848 0.15 ENST00000264233.5
POLQ
polymerase (DNA directed), theta
chr15_+_96904487 0.14 ENST00000600790.1
AC087477.1
Uncharacterized protein
chrX_-_109683446 0.14 ENST00000372057.1
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr3_+_113616317 0.14 ENST00000440446.2
ENST00000488680.1
GRAMD1C
GRAM domain containing 1C
chr8_-_72268968 0.14 ENST00000388740.3
EYA1
eyes absent homolog 1 (Drosophila)
chr9_+_130026756 0.14 ENST00000314904.5
ENST00000373387.4
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr8_-_71157595 0.14 ENST00000519724.1
NCOA2
nuclear receptor coactivator 2
chr10_-_62060232 0.14 ENST00000503925.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr4_-_23891693 0.14 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr8_-_73793975 0.14 ENST00000523881.1
RP11-1145L24.1
RP11-1145L24.1
chr7_-_44105158 0.14 ENST00000297283.3
PGAM2
phosphoglycerate mutase 2 (muscle)
chr9_+_127054254 0.14 ENST00000422297.1
NEK6
NIMA-related kinase 6
chr4_+_41362796 0.13 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIMCH1
LIM and calponin homology domains 1
chrX_-_119693745 0.13 ENST00000371323.2
CUL4B
cullin 4B
chr14_+_62462541 0.13 ENST00000430451.2
SYT16
synaptotagmin XVI
chr15_-_52970820 0.13 ENST00000261844.7
ENST00000399202.4
ENST00000562135.1
FAM214A
family with sequence similarity 214, member A
chr9_+_127054217 0.13 ENST00000394199.2
ENST00000546191.1
NEK6
NIMA-related kinase 6
chr12_-_57644952 0.12 ENST00000554578.1
ENST00000546246.2
ENST00000553489.1
ENST00000332782.2
STAC3
SH3 and cysteine rich domain 3
chr1_+_201979743 0.12 ENST00000446188.1
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr13_+_51483814 0.12 ENST00000336617.3
ENST00000422660.1
RNASEH2B
ribonuclease H2, subunit B
chr14_-_23652849 0.12 ENST00000316902.7
ENST00000469263.1
ENST00000525062.1
ENST00000524758.1
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr8_+_1993173 0.11 ENST00000523438.1
MYOM2
myomesin 2
chr2_-_148778258 0.11 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
ORC4
origin recognition complex, subunit 4
chr7_+_120629653 0.11 ENST00000450913.2
ENST00000340646.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr1_-_204436344 0.11 ENST00000367184.2
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr8_-_72268889 0.11 ENST00000388742.4
EYA1
eyes absent homolog 1 (Drosophila)
chr5_-_142065223 0.11 ENST00000378046.1
FGF1
fibroblast growth factor 1 (acidic)
chr22_+_19706958 0.11 ENST00000395109.2
SEPT5
septin 5
chr9_+_100263912 0.11 ENST00000259365.4
TMOD1
tropomodulin 1
chrX_-_138304939 0.11 ENST00000448673.1
FGF13
fibroblast growth factor 13
chr3_-_176914238 0.10 ENST00000430069.1
ENST00000428970.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr1_+_156096336 0.10 ENST00000504687.1
ENST00000473598.2
LMNA
lamin A/C
chr7_+_129906660 0.10 ENST00000222481.4
CPA2
carboxypeptidase A2 (pancreatic)
chr17_+_17685422 0.10 ENST00000395774.1
RAI1
retinoic acid induced 1
chr4_+_129730779 0.10 ENST00000226319.6
PHF17
jade family PHD finger 1
chr4_+_160203650 0.10 ENST00000514565.1
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr1_+_228395755 0.10 ENST00000284548.11
ENST00000570156.2
ENST00000422127.1
ENST00000366707.4
ENST00000366709.4
OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chrX_-_131353461 0.10 ENST00000370874.1
RAP2C
RAP2C, member of RAS oncogene family
chr5_+_67584174 0.10 ENST00000320694.8
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr12_-_57472522 0.10 ENST00000379391.3
ENST00000300128.4
TMEM194A
transmembrane protein 194A
chr17_-_45899126 0.09 ENST00000007414.3
ENST00000392507.3
OSBPL7
oxysterol binding protein-like 7
chr3_-_176914191 0.09 ENST00000437738.1
ENST00000424913.1
ENST00000443315.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr3_+_36421971 0.09 ENST00000457375.2
ENST00000434649.1
STAC
SH3 and cysteine rich domain
chr8_+_101349823 0.09 ENST00000519566.1
KB-1991G8.1
KB-1991G8.1
chr8_+_104831472 0.09 ENST00000262231.10
ENST00000507740.1
RIMS2
regulating synaptic membrane exocytosis 2
chr4_-_15661474 0.09 ENST00000509314.1
ENST00000503196.1
FBXL5
F-box and leucine-rich repeat protein 5
chr15_+_78830023 0.09 ENST00000599596.1
AC027228.1
HCG2005369; Uncharacterized protein
chr9_-_134585221 0.09 ENST00000372190.3
ENST00000427994.1
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr8_+_86999516 0.09 ENST00000521564.1
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr3_+_52448539 0.09 ENST00000461861.1
PHF7
PHD finger protein 7
chr22_-_36031181 0.09 ENST00000594060.1
AL049747.1
AL049747.1
chr14_-_61748550 0.09 ENST00000555868.1
TMEM30B
transmembrane protein 30B
chr2_-_235405679 0.09 ENST00000390645.2
ARL4C
ADP-ribosylation factor-like 4C
chr19_-_893200 0.09 ENST00000269814.4
ENST00000395808.3
ENST00000312090.6
ENST00000325464.1
MED16
mediator complex subunit 16
chr7_-_55583740 0.09 ENST00000453256.1
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr1_+_201979645 0.09 ENST00000367284.5
ENST00000367283.3
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr2_+_109204909 0.09 ENST00000393310.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr14_-_94421923 0.09 ENST00000555507.1
ASB2
ankyrin repeat and SOCS box containing 2
chr11_+_1940925 0.09 ENST00000453458.1
ENST00000381557.2
ENST00000381589.3
ENST00000381579.3
ENST00000381563.4
ENST00000344578.4
TNNT3
troponin T type 3 (skeletal, fast)
chr10_+_32856764 0.08 ENST00000375030.2
ENST00000375028.3
C10orf68
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr15_-_70994612 0.08 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr7_-_124569991 0.08 ENST00000446993.1
ENST00000357628.3
ENST00000393329.1
POT1
protection of telomeres 1
chr5_+_173316341 0.08 ENST00000520867.1
ENST00000334035.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr2_+_30569506 0.08 ENST00000421976.2
AC109642.1
AC109642.1
chr17_-_42200996 0.08 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
HDAC5
histone deacetylase 5
chr11_+_19799327 0.08 ENST00000540292.1
NAV2
neuron navigator 2
chr22_+_25595817 0.08 ENST00000215855.2
ENST00000404334.1
CRYBB3
crystallin, beta B3
chr4_+_160025300 0.08 ENST00000505478.1
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr12_+_116985896 0.08 ENST00000547114.1
RP11-809C9.2
RP11-809C9.2
chr16_+_14280564 0.08 ENST00000572567.1
MKL2
MKL/myocardin-like 2
chr1_-_12677714 0.08 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr6_-_169654139 0.08 ENST00000366787.3
THBS2
thrombospondin 2
chrX_+_135279179 0.08 ENST00000370676.3
FHL1
four and a half LIM domains 1
chr10_+_88428370 0.08 ENST00000372066.3
ENST00000263066.6
ENST00000372056.4
ENST00000310944.6
ENST00000361373.4
ENST00000542786.1
LDB3
LIM domain binding 3
chr20_-_44519839 0.08 ENST00000372518.4
NEURL2
neuralized E3 ubiquitin protein ligase 2
chr4_-_25865159 0.08 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr18_-_19283649 0.08 ENST00000584464.1
ENST00000578270.1
ABHD3
abhydrolase domain containing 3
chr15_-_93353028 0.07 ENST00000557398.2
FAM174B
family with sequence similarity 174, member B
chr12_+_109569155 0.07 ENST00000539864.1
ACACB
acetyl-CoA carboxylase beta
chr11_-_85780853 0.07 ENST00000531930.1
ENST00000528398.1
PICALM
phosphatidylinositol binding clathrin assembly protein
chr14_+_76776957 0.07 ENST00000512784.1
ESRRB
estrogen-related receptor beta
chr1_+_114473350 0.07 ENST00000503968.1
HIPK1
homeodomain interacting protein kinase 1
chr12_-_49393092 0.07 ENST00000421952.2
DDN
dendrin
chr3_-_38071122 0.07 ENST00000334661.4
PLCD1
phospholipase C, delta 1
chr7_+_80267973 0.07 ENST00000394788.3
ENST00000447544.2
CD36
CD36 molecule (thrombospondin receptor)
chr3_-_108248169 0.07 ENST00000273353.3
MYH15
myosin, heavy chain 15
chr14_+_56046914 0.07 ENST00000413890.2
ENST00000395309.3
ENST00000554567.1
ENST00000555498.1
KTN1
kinectin 1 (kinesin receptor)
chr3_+_138067521 0.07 ENST00000494949.1
MRAS
muscle RAS oncogene homolog
chr3_+_8543533 0.07 ENST00000454244.1
LMCD1
LIM and cysteine-rich domains 1
chr10_+_71562180 0.07 ENST00000517713.1
ENST00000522165.1
ENST00000520133.1
COL13A1
collagen, type XIII, alpha 1
chr12_+_14561422 0.07 ENST00000541056.1
ATF7IP
activating transcription factor 7 interacting protein
chr15_+_100106244 0.07 ENST00000557942.1
MEF2A
myocyte enhancer factor 2A
chr4_+_41614909 0.07 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr15_+_78558523 0.07 ENST00000446172.2
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr8_+_1993152 0.07 ENST00000262113.4
MYOM2
myomesin 2
chr20_+_58251716 0.07 ENST00000355648.4
PHACTR3
phosphatase and actin regulator 3
chr14_+_39735411 0.07 ENST00000603904.1
RP11-407N17.3
cTAGE family member 5 isoform 4
chr4_+_86699834 0.06 ENST00000395183.2
ARHGAP24
Rho GTPase activating protein 24
chrX_-_15683147 0.06 ENST00000380342.3
TMEM27
transmembrane protein 27
chr2_+_220299547 0.06 ENST00000312358.7
SPEG
SPEG complex locus
chr5_-_142065612 0.06 ENST00000360966.5
ENST00000411960.1
FGF1
fibroblast growth factor 1 (acidic)
chr18_+_29027696 0.06 ENST00000257189.4
DSG3
desmoglein 3
chr9_-_21995249 0.06 ENST00000494262.1
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr10_-_14880002 0.06 ENST00000465530.1
CDNF
cerebral dopamine neurotrophic factor
chr12_-_22094336 0.06 ENST00000326684.4
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr2_-_148778323 0.06 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4
origin recognition complex, subunit 4
chr8_-_94029882 0.06 ENST00000520686.1
TRIQK
triple QxxK/R motif containing
chr7_-_105332084 0.06 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr1_+_92632542 0.06 ENST00000409154.4
ENST00000370378.4
KIAA1107
KIAA1107
chr2_-_148779106 0.06 ENST00000416719.1
ENST00000264169.2
ORC4
origin recognition complex, subunit 4
chr4_+_113970772 0.06 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2
ankyrin 2, neuronal
chr11_+_12766583 0.06 ENST00000361985.2
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr5_-_16509101 0.06 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr3_+_138067666 0.06 ENST00000475711.1
ENST00000464896.1
MRAS
muscle RAS oncogene homolog
chr4_+_110834033 0.05 ENST00000509793.1
ENST00000265171.5
EGF
epidermal growth factor
chr3_+_154797877 0.05 ENST00000462745.1
ENST00000493237.1
MME
membrane metallo-endopeptidase
chr14_+_56046990 0.05 ENST00000438792.2
ENST00000395314.3
ENST00000395308.1
KTN1
kinectin 1 (kinesin receptor)
chr15_+_100106126 0.05 ENST00000558812.1
ENST00000338042.6
MEF2A
myocyte enhancer factor 2A
chr3_+_4535025 0.05 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr2_+_232575168 0.05 ENST00000440384.1
PTMA
prothymosin, alpha
chr17_-_79900255 0.05 ENST00000330655.3
ENST00000582198.1
MYADML2
PYCR1
myeloid-associated differentiation marker-like 2
pyrroline-5-carboxylate reductase 1
chr3_-_149510553 0.05 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ANKUB1
ankyrin repeat and ubiquitin domain containing 1
chr9_+_127023704 0.05 ENST00000373596.1
ENST00000425237.1
NEK6
NIMA-related kinase 6
chr2_-_157198860 0.05 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr7_-_151217166 0.05 ENST00000496004.1
RHEB
Ras homolog enriched in brain
chr11_+_7597639 0.05 ENST00000533792.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr9_+_116327326 0.05 ENST00000342620.5
RGS3
regulator of G-protein signaling 3
chr7_+_152456829 0.05 ENST00000377776.3
ENST00000256001.8
ENST00000397282.2
ACTR3B
ARP3 actin-related protein 3 homolog B (yeast)
chr8_+_132952112 0.05 ENST00000520362.1
ENST00000519656.1
EFR3A
EFR3 homolog A (S. cerevisiae)
chr3_+_154798162 0.05 ENST00000360490.2
MME
membrane metallo-endopeptidase
chr15_+_80364901 0.05 ENST00000560228.1
ENST00000559835.1
ENST00000559775.1
ENST00000558688.1
ENST00000560392.1
ENST00000560976.1
ENST00000558272.1
ENST00000558390.1
ZFAND6
zinc finger, AN1-type domain 6
chr15_+_40531243 0.05 ENST00000558055.1
ENST00000455577.2
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr2_+_103378472 0.05 ENST00000412401.2
TMEM182
transmembrane protein 182
chrX_-_50386648 0.05 ENST00000460112.3
SHROOM4
shroom family member 4
chr9_+_5231413 0.05 ENST00000239316.4
INSL4
insulin-like 4 (placenta)
chr2_-_190044480 0.05 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr17_-_48785216 0.05 ENST00000285243.6
ANKRD40
ankyrin repeat domain 40
chr14_+_58797974 0.05 ENST00000417477.2
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr1_-_206945830 0.05 ENST00000423557.1
IL10
interleukin 10
chr9_+_97766469 0.05 ENST00000433691.2
C9orf3
chromosome 9 open reading frame 3
chrX_+_131157609 0.04 ENST00000496850.1
MST4
Serine/threonine-protein kinase MST4
chr11_+_45918092 0.04 ENST00000395629.2
MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr4_-_52883786 0.04 ENST00000343457.3
LRRC66
leucine rich repeat containing 66
chr3_+_50316458 0.04 ENST00000316436.3
LSMEM2
leucine-rich single-pass membrane protein 2
chr14_-_65409502 0.04 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr12_-_46766577 0.04 ENST00000256689.5
SLC38A2
solute carrier family 38, member 2
chr10_-_96829246 0.04 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8
chr18_+_12407895 0.04 ENST00000590956.1
ENST00000336990.4
ENST00000440960.1
ENST00000588729.1
SLMO1
slowmo homolog 1 (Drosophila)
chr4_-_140098339 0.04 ENST00000394235.2
ELF2
E74-like factor 2 (ets domain transcription factor)
chr9_+_97766409 0.04 ENST00000425634.2
C9orf3
chromosome 9 open reading frame 3
chr15_+_40531621 0.04 ENST00000560346.1
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr2_+_220144168 0.04 ENST00000392087.2
ENST00000442681.1
ENST00000439026.1
DNAJB2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr7_+_152456904 0.04 ENST00000537264.1
ACTR3B
ARP3 actin-related protein 3 homolog B (yeast)
chr3_-_112360116 0.04 ENST00000206423.3
ENST00000439685.2
CCDC80
coiled-coil domain containing 80
chr7_+_80231466 0.04 ENST00000309881.7
ENST00000534394.1
CD36
CD36 molecule (thrombospondin receptor)
chr14_-_65409438 0.04 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr1_-_150693318 0.04 ENST00000442853.1
ENST00000368995.4
ENST00000368993.2
ENST00000361824.2
ENST00000322343.7
HORMAD1
HORMA domain containing 1
chrX_+_18725758 0.04 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1
protein phosphatase, EF-hand calcium binding domain 1
chrX_+_153046456 0.04 ENST00000393786.3
ENST00000370104.1
ENST00000370108.3
ENST00000370101.3
ENST00000430541.1
ENST00000370100.1
SRPK3
SRSF protein kinase 3
chr11_+_1940786 0.04 ENST00000278317.6
ENST00000381561.4
ENST00000381548.3
ENST00000360603.3
ENST00000381549.3
TNNT3
troponin T type 3 (skeletal, fast)
chr2_+_179149636 0.04 ENST00000409631.1
OSBPL6
oxysterol binding protein-like 6
chr8_-_125827922 0.04 ENST00000533516.1
RP11-1082L8.4
RP11-1082L8.4
chr5_+_140749803 0.04 ENST00000576222.1
PCDHGB3
protocadherin gamma subfamily B, 3
chr4_-_186697044 0.04 ENST00000437304.2
SORBS2
sorbin and SH3 domain containing 2
chr5_-_137475071 0.03 ENST00000265191.2
NME5
NME/NM23 family member 5
chr14_+_100204027 0.03 ENST00000554479.1
ENST00000555145.1
EML1
echinoderm microtubule associated protein like 1
chr10_+_102758105 0.03 ENST00000429732.1
LZTS2
leucine zipper, putative tumor suppressor 2
chr21_+_39628655 0.03 ENST00000398925.1
ENST00000398928.1
ENST00000328656.4
ENST00000443341.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr1_+_230193521 0.03 ENST00000543760.1
GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr1_-_201390846 0.03 ENST00000367312.1
ENST00000555340.2
ENST00000361379.4
TNNI1
troponin I type 1 (skeletal, slow)
chr17_-_42188598 0.03 ENST00000591714.1
HDAC5
histone deacetylase 5
chr16_+_14280742 0.03 ENST00000341243.5
MKL2
MKL/myocardin-like 2
chr11_-_116708302 0.03 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
APOA1
apolipoprotein A-I
chr2_+_109204743 0.03 ENST00000332345.6
LIMS1
LIM and senescent cell antigen-like domains 1

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2C

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:2000974 negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.3 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.2 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.1 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.2 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.3 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.2 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.2 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) positive regulation of mitochondrial DNA metabolic process(GO:1901860) response to methionine(GO:1904640)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.2 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.2 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.0 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.2 GO:0035768 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.0 0.1 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.2 GO:0060613 fat pad development(GO:0060613)
0.0 0.0 GO:0060629 regulation of homologous chromosome segregation(GO:0060629)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.2 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.1 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.1 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.0 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.6 GO:0005861 troponin complex(GO:0005861)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.0 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.6 GO:0031014 troponin T binding(GO:0031014)
0.0 0.2 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation