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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MAF_NRL

Z-value: 1.01

Motif logo

Transcription factors associated with MAF_NRL

Gene Symbol Gene ID Gene Info
ENSG00000178573.6 MAF bZIP transcription factor
ENSG00000129535.8 neural retina leucine zipper

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NRLhg19_v2_chr14_-_24551137_245511780.862.8e-02Click!
MAFhg19_v2_chr16_-_79633799_796338720.843.7e-02Click!

Activity profile of MAF_NRL motif

Sorted Z-values of MAF_NRL motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_2924720 0.72 ENST00000455942.2
solute carrier family 22 (organic cation transporter), member 18 antisense
chr5_-_159766528 0.64 ENST00000505287.2
cyclin J-like
chr16_+_777739 0.61 ENST00000563792.1
hydroxyacylglutathione hydrolase-like
chr14_-_103989033 0.44 ENST00000553878.1
ENST00000557530.1
creatine kinase, brain
chr19_-_18391708 0.44 ENST00000600972.1
jun D proto-oncogene
chr1_-_11115877 0.44 ENST00000490101.1
spermidine synthase
chr20_-_48530230 0.41 ENST00000422556.1
spermatogenesis associated 2
chr8_-_145018905 0.40 ENST00000398774.2
plectin
chr22_+_42196666 0.39 ENST00000402061.3
ENST00000255784.5
coiled-coil domain containing 134
chr19_+_52076425 0.37 ENST00000436511.2
zinc finger protein 175
chr11_-_45928830 0.35 ENST00000449465.1
chromosome 11 open reading frame 94
chr19_+_39897943 0.34 ENST00000600033.1
ZFP36 ring finger protein
chr11_-_128775930 0.33 ENST00000524878.1
chromosome 11 open reading frame 45
chr16_-_1821496 0.33 ENST00000564628.1
ENST00000563498.1
NME/NM23 nucleoside diphosphate kinase 3
chr6_-_13290684 0.32 ENST00000606393.1
RP1-257A7.5
chr17_-_73874654 0.32 ENST00000254816.2
tripartite motif containing 47
chr12_+_47610315 0.31 ENST00000548348.1
ENST00000549500.1
PC-esterase domain containing 1B
chr19_+_7599597 0.31 ENST00000414982.3
ENST00000450331.3
patatin-like phospholipase domain containing 6
chr6_-_33297013 0.30 ENST00000453407.1
death-domain associated protein
chr16_-_4664382 0.30 ENST00000591113.1
UBA-like domain containing 1
chr17_-_4448361 0.30 ENST00000572759.1
MYB binding protein (P160) 1a
chr1_+_24646263 0.28 ENST00000524724.1
grainyhead-like 3 (Drosophila)
chr16_-_67260901 0.28 ENST00000341546.3
ENST00000409509.1
ENST00000433915.1
ENST00000454102.2
leucine rich repeat containing 29
Uncharacterized protein; cDNA FLJ57407, weakly similar to Mus musculus leucine rich repeat containing 29 (Lrrc29), mRNA
chr19_+_39759154 0.28 ENST00000331982.5
interferon, lambda 2
chr17_+_7253667 0.27 ENST00000570504.1
ENST00000574499.1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr5_+_172484377 0.27 ENST00000523161.1
CREB3 regulatory factor
chr5_+_140019004 0.27 ENST00000394671.3
ENST00000511410.1
ENST00000537378.1
transmembrane and coiled-coil domains 6
chr19_+_13122980 0.27 ENST00000590027.1
nuclear factor I/X (CCAAT-binding transcription factor)
chr7_+_2685164 0.26 ENST00000400376.2
tweety family member 3
chr16_-_31076332 0.26 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
zinc finger protein 668
chr17_+_48610074 0.25 ENST00000503690.1
ENST00000514874.1
ENST00000537145.1
ENST00000541226.1
epsin 3
chr8_-_145086922 0.25 ENST00000530478.1
poly (ADP-ribose) polymerase family, member 10
chr1_-_16539094 0.25 ENST00000270747.3
Rho guanine nucleotide exchange factor (GEF) 19
chr19_+_42806250 0.25 ENST00000598490.1
ENST00000341747.3
proline rich 19
chr4_+_160188306 0.24 ENST00000510510.1
Rap guanine nucleotide exchange factor (GEF) 2
chr4_-_168155577 0.24 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr3_-_88108192 0.24 ENST00000309534.6
CGG triplet repeat binding protein 1
chr14_+_96343100 0.24 ENST00000503525.2
long intergenic non-protein coding RNA 617
chr9_-_131486367 0.23 ENST00000372663.4
ENST00000406904.2
ENST00000452105.1
ENST00000372672.2
ENST00000372667.5
zinc finger, DHHC-type containing 12
chr19_+_50887585 0.23 ENST00000440232.2
ENST00000601098.1
ENST00000599857.1
ENST00000593887.1
polymerase (DNA directed), delta 1, catalytic subunit
chr3_-_138553779 0.23 ENST00000461451.1
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr1_-_57431679 0.23 ENST00000371237.4
ENST00000535057.1
ENST00000543257.1
complement component 8, beta polypeptide
chr2_+_120187465 0.22 ENST00000409826.1
ENST00000417645.1
transmembrane protein 37
chr3_-_69591727 0.22 ENST00000459638.1
FERM domain containing 4B
chr2_-_129076151 0.22 ENST00000259241.6
heparan sulfate 6-O-sulfotransferase 1
chr10_+_70980051 0.22 ENST00000354624.5
ENST00000395086.2
hexokinase domain containing 1
chr11_+_393428 0.22 ENST00000533249.1
ENST00000527442.1
plakophilin 3
chr2_-_178129551 0.22 ENST00000430047.1
nuclear factor, erythroid 2-like 2
chr6_-_109703663 0.21 ENST00000368961.5
CD164 molecule, sialomucin
chr7_+_2695726 0.21 ENST00000429448.1
tweety family member 3
chr13_-_111214015 0.21 ENST00000267328.3
RAB20, member RAS oncogene family
chr1_-_16302608 0.20 ENST00000375743.4
ENST00000375733.2
zinc finger and BTB domain containing 17
chr7_-_8302298 0.20 ENST00000446305.1
islet cell autoantigen 1, 69kDa
chr14_+_105927191 0.20 ENST00000550551.1
metastasis associated 1
chr14_-_23834411 0.20 ENST00000429593.2
embryonal Fyn-associated substrate
chr19_-_46285736 0.20 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
dystrophia myotonica-protein kinase
chr8_+_125860939 0.20 ENST00000525292.1
ENST00000528090.1
long intergenic non-protein coding RNA 964
chr15_-_75248954 0.20 ENST00000499788.2
ribonuclease P/MRP 25kDa subunit
chr17_-_28619059 0.20 ENST00000580709.1
bleomycin hydrolase
chr1_+_178694408 0.20 ENST00000324778.5
Ral GEF with PH domain and SH3 binding motif 2
chr5_+_174151536 0.20 ENST00000239243.6
ENST00000507785.1
msh homeobox 2
chr11_-_46638378 0.20 ENST00000529192.1
harbinger transposase derived 1
chr16_-_4664860 0.19 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
ENST00000591401.1
ENST00000283474.7
UBA-like domain containing 1
chr3_+_193853927 0.19 ENST00000232424.3
hes family bHLH transcription factor 1
chr1_-_1763721 0.19 ENST00000437146.1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr17_-_74489215 0.19 ENST00000585701.1
ENST00000591192.1
ENST00000589526.1
rhomboid 5 homolog 2 (Drosophila)
chr1_-_149814478 0.19 ENST00000369161.3
histone cluster 2, H2aa3
chr10_+_5566916 0.19 ENST00000315238.1
calmodulin-like 3
chr19_-_50381606 0.19 ENST00000391830.1
AKT1 substrate 1 (proline-rich)
chr22_+_22676808 0.19 ENST00000390290.2
immunoglobulin lambda variable 1-51
chr1_+_233749739 0.19 ENST00000366621.3
potassium channel, subfamily K, member 1
chr6_-_24799117 0.19 ENST00000565469.1
chromosome 6 open reading frame 229
chr11_-_110968081 0.18 ENST00000603154.1
RP11-89C3.4
chr20_-_60942326 0.18 ENST00000370677.3
ENST00000370692.3
laminin, alpha 5
chr14_+_61447832 0.18 ENST00000354886.2
ENST00000267488.4
solute carrier family 38, member 6
chr1_+_24646002 0.18 ENST00000356046.2
grainyhead-like 3 (Drosophila)
chr9_+_139746792 0.18 ENST00000317446.2
ENST00000445819.1
MAM domain containing 4
chr11_+_111169565 0.18 ENST00000528846.1
colorectal cancer associated 2
chr8_+_128747661 0.18 ENST00000259523.6
v-myc avian myelocytomatosis viral oncogene homolog
chr1_+_45274154 0.18 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTB (POZ) domain containing 19
chr11_-_66103932 0.18 ENST00000311320.4
Ras and Rab interactor 1
chr4_-_57547454 0.18 ENST00000556376.2
HOP homeobox
chr7_+_99816859 0.18 ENST00000317271.2
poliovirus receptor related immunoglobulin domain containing
chr1_+_24645807 0.18 ENST00000361548.4
grainyhead-like 3 (Drosophila)
chr14_+_96342729 0.17 ENST00000504119.1
long intergenic non-protein coding RNA 617
chr14_+_23654525 0.17 ENST00000399910.1
ENST00000492621.1
chromosome 14 open reading frame 164
chr1_+_24645865 0.17 ENST00000342072.4
grainyhead-like 3 (Drosophila)
chr7_-_56160625 0.17 ENST00000446428.1
ENST00000432123.1
ENST00000452681.2
ENST00000537360.1
phosphorylase kinase, gamma 1 (muscle)
chr8_-_10336885 0.17 ENST00000520494.1
RP11-981G7.3
chr19_-_38747172 0.17 ENST00000347262.4
ENST00000591585.1
ENST00000301242.4
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr4_+_8201091 0.17 ENST00000382521.3
ENST00000245105.3
ENST00000457650.2
ENST00000539824.1
SH3 domain and tetratricopeptide repeats 1
chr21_-_31588338 0.17 ENST00000286809.1
claudin 8
chr6_-_3456267 0.17 ENST00000485307.1
solute carrier family 22, member 23
chr16_+_128062 0.17 ENST00000356432.3
ENST00000219431.4
N-methylpurine-DNA glycosylase
chr1_-_22222764 0.17 ENST00000439717.2
ENST00000412328.1
heparan sulfate proteoglycan 2
chr19_+_7599792 0.17 ENST00000600942.1
ENST00000593924.1
patatin-like phospholipase domain containing 6
chr1_+_61869748 0.17 ENST00000357977.5
nuclear factor I/A
chr4_-_57547870 0.16 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOP homeobox
chr10_-_5446786 0.16 ENST00000479328.1
ENST00000380419.3
tubulin, alpha-like 3
chr16_-_4665023 0.16 ENST00000591897.1
UBA-like domain containing 1
chr17_-_63052929 0.16 ENST00000439174.2
guanine nucleotide binding protein (G protein), alpha 13
chr17_-_39674668 0.16 ENST00000393981.3
keratin 15
chr19_+_535835 0.16 ENST00000607527.1
ENST00000606065.1
cell division cycle 34
chr8_-_145025044 0.16 ENST00000322810.4
plectin
chr4_+_154125565 0.16 ENST00000338700.5
tripartite motif containing 2
chr16_+_67233412 0.16 ENST00000477898.1
engulfment and cell motility 3
chr20_-_60942361 0.15 ENST00000252999.3
laminin, alpha 5
chr11_-_1780261 0.15 ENST00000427721.1
RP11-295K3.1
chr6_-_100016678 0.15 ENST00000523799.1
ENST00000520429.1
cyclin C
chr14_+_101295948 0.15 ENST00000452514.2
maternally expressed 3 (non-protein coding)
chr19_-_51538148 0.15 ENST00000319590.4
ENST00000250351.4
kallikrein-related peptidase 12
chr16_-_70712229 0.15 ENST00000562883.2
metastasis suppressor 1-like
chr10_-_81932771 0.15 ENST00000437799.1
annexin A11
chr5_+_140019079 0.15 ENST00000252100.6
transmembrane and coiled-coil domains 6
chr16_+_83986827 0.15 ENST00000393306.1
ENST00000565123.1
oxidative stress induced growth inhibitor 1
chr16_+_3162557 0.15 ENST00000382192.3
ENST00000219091.4
ENST00000444510.2
ENST00000414351.1
zinc finger protein 205
chr1_-_16302565 0.14 ENST00000537142.1
ENST00000448462.2
zinc finger and BTB domain containing 17
chr3_+_50192499 0.14 ENST00000413852.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr2_-_97536490 0.14 ENST00000449330.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr17_-_74276438 0.14 ENST00000532549.1
glutamine rich 2
chr12_-_11422630 0.14 ENST00000381842.3
ENST00000538488.1
proline-rich protein BstNI subfamily 3
chr10_-_98347063 0.14 ENST00000443638.1
transmembrane 9 superfamily member 3
chr3_-_48601206 0.14 ENST00000273610.3
urocortin 2
chr3_-_47484661 0.14 ENST00000495603.2
SREBF chaperone
chr22_-_39150947 0.14 ENST00000411587.2
ENST00000420859.1
ENST00000452294.1
ENST00000456894.1
Sad1 and UNC84 domain containing 2
chr12_+_132628963 0.14 ENST00000330579.1
nucleolar complex associated 4 homolog (S. cerevisiae)
chr15_+_71184931 0.14 ENST00000560369.1
ENST00000260382.5
leucine rich repeat containing 49
chr9_+_139557360 0.14 ENST00000308874.7
ENST00000406555.3
ENST00000492862.2
EGF-like-domain, multiple 7
chr14_+_105957402 0.14 ENST00000421892.1
ENST00000334656.7
ENST00000451719.1
ENST00000392522.3
ENST00000392523.4
ENST00000354560.6
ENST00000450383.1
chromosome 14 open reading frame 80
chr6_-_31938700 0.14 ENST00000495340.1
decapping exoribonuclease
chr19_+_50094866 0.14 ENST00000418929.2
proline rich 12
chrX_-_153775426 0.14 ENST00000393562.2
glucose-6-phosphate dehydrogenase
chr16_-_67260691 0.14 ENST00000447579.1
ENST00000393992.1
ENST00000424285.1
leucine rich repeat containing 29
chr11_-_65429891 0.13 ENST00000527874.1
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr9_-_98279241 0.13 ENST00000437951.1
ENST00000375274.2
ENST00000430669.2
ENST00000468211.2
patched 1
chr19_-_49955050 0.13 ENST00000262265.5
PIH1 domain containing 1
chr7_+_151791095 0.13 ENST00000422997.2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr6_-_33385854 0.13 ENST00000488478.1
cutA divalent cation tolerance homolog (E. coli)
chr17_-_36358166 0.13 ENST00000537432.1
TBC1 domain family, member 3
chr2_+_145780767 0.13 ENST00000599358.1
ENST00000596278.1
ENST00000596747.1
ENST00000608652.1
ENST00000609705.1
ENST00000608432.1
ENST00000596970.1
ENST00000602041.1
ENST00000601578.1
ENST00000596034.1
ENST00000414195.2
ENST00000594837.1
testis expressed 41 (non-protein coding)
chr1_+_163291680 0.13 ENST00000450453.2
ENST00000524800.1
ENST00000442820.1
ENST00000367900.3
NUF2, NDC80 kinetochore complex component
chr16_+_67197288 0.13 ENST00000264009.8
ENST00000421453.1
heat shock transcription factor 4
chr1_+_223354486 0.13 ENST00000446145.1
RP11-239E10.3
chr7_+_29603394 0.13 ENST00000319694.2
proline rich 15
chr11_-_77791156 0.13 ENST00000281031.4
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
chr2_-_23747214 0.13 ENST00000430988.1
Uncharacterized protein
chrX_-_45060135 0.13 ENST00000398000.2
ENST00000377934.4
chromosome X open reading frame 36
chr5_+_132009675 0.13 ENST00000231449.2
ENST00000350025.2
interleukin 4
chr5_-_90610200 0.13 ENST00000511918.1
ENST00000513626.1
ENST00000607854.1
lung cancer associated transcript 1 (non-protein coding)
RP11-213H15.4
chr17_-_76128488 0.13 ENST00000322914.3
transmembrane channel-like 6
chrX_+_53078465 0.12 ENST00000375466.2
G protein-coupled receptor 173
chr16_-_30537839 0.12 ENST00000380412.5
zinc finger protein 768
chr7_+_76139925 0.12 ENST00000394849.1
uroplakin 3B
chr21_-_15918618 0.12 ENST00000400564.1
ENST00000400566.1
SAM domain, SH3 domain and nuclear localization signals 1
chr3_-_123339418 0.12 ENST00000583087.1
myosin light chain kinase
chr6_-_116833500 0.12 ENST00000356128.4
trafficking protein particle complex 3-like
chr11_-_615570 0.12 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
interferon regulatory factor 7
chr17_-_39769005 0.12 ENST00000301653.4
ENST00000593067.1
keratin 16
chr16_+_2510081 0.12 ENST00000361837.4
ENST00000569496.1
ENST00000567489.1
ENST00000563531.1
ENST00000483320.1
chromosome 16 open reading frame 59
chr17_-_73505961 0.12 ENST00000433559.2
CASK interacting protein 2
chr9_-_140351928 0.12 ENST00000339554.3
NMDA receptor synaptonuclear signaling and neuronal migration factor
chr12_+_56615761 0.12 ENST00000447747.1
ENST00000399713.2
nucleic acid binding protein 2
chr19_-_55628927 0.12 ENST00000263433.3
ENST00000376393.2
protein phosphatase 1, regulatory subunit 12C
chr13_-_47471155 0.12 ENST00000543956.1
ENST00000542664.1
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr11_+_82868185 0.12 ENST00000530304.1
ENST00000533018.1
PCF11 cleavage and polyadenylation factor subunit
chr1_-_25573937 0.12 ENST00000417642.2
ENST00000431849.2
chromosome 1 open reading frame 63
chr19_-_44388116 0.12 ENST00000587539.1
zinc finger protein 404
chr22_+_50981079 0.12 ENST00000609268.1
CTA-384D8.34
chr19_+_13228917 0.12 ENST00000586171.1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr21_+_30502806 0.12 ENST00000399928.1
ENST00000399926.1
MAP3K7 C-terminal like
chrX_+_70364667 0.11 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
neuroligin 3
chr11_-_1606513 0.11 ENST00000382171.2
keratin associated protein 5-1
chr15_+_96875657 0.11 ENST00000559679.1
ENST00000394171.2
nuclear receptor subfamily 2, group F, member 2
chr19_+_17579556 0.11 ENST00000442725.1
solute carrier family 27 (fatty acid transporter), member 1
chr19_-_51537982 0.11 ENST00000525263.1
kallikrein-related peptidase 12
chr11_+_10326612 0.11 ENST00000534464.1
ENST00000530439.1
ENST00000524948.1
ENST00000528655.1
ENST00000526492.1
ENST00000525063.1
adrenomedullin
chr5_+_167956121 0.11 ENST00000338333.4
fibrillarin-like 1
chr19_-_51530916 0.11 ENST00000594768.1
kallikrein-related peptidase 11
chr15_-_82338460 0.11 ENST00000558133.1
ENST00000329713.4
mex-3 RNA binding family member B
chr15_-_68497657 0.11 ENST00000448060.2
ENST00000467889.1
calmodulin-like 4
chr12_-_66275350 0.11 ENST00000536648.1
Uncharacterized protein
chr4_+_6642404 0.11 ENST00000507420.1
ENST00000382581.4
Morf4 family associated protein 1
chr5_+_35852797 0.11 ENST00000508941.1
interleukin 7 receptor
chr20_-_22565101 0.11 ENST00000419308.2
forkhead box A2
chr1_-_27480973 0.11 ENST00000545949.1
ENST00000374086.3
solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
chr14_+_93118813 0.11 ENST00000556418.1
Ras and Rab interactor 3
chr10_+_96443204 0.11 ENST00000339022.5
cytochrome P450, family 2, subfamily C, polypeptide 18
chr3_+_13610216 0.11 ENST00000492059.1
fibulin 2
chr2_+_234296792 0.11 ENST00000409813.3
diacylglycerol kinase, delta 130kDa
chr19_-_55628700 0.11 ENST00000592993.1
protein phosphatase 1, regulatory subunit 12C
chr12_+_19358192 0.11 ENST00000538305.1
pleckstrin homology domain containing, family A member 5
chr7_-_94285402 0.11 ENST00000428696.2
ENST00000445866.2
sarcoglycan, epsilon
chr7_-_35013217 0.11 ENST00000446375.1
dpy-19-like 1 (C. elegans)
chr17_+_7341586 0.11 ENST00000575235.1
fibroblast growth factor 11
chr20_+_19738300 0.11 ENST00000432334.1
RP1-122P22.2
chr6_-_166401527 0.11 ENST00000455853.1
ENST00000584911.1
long intergenic non-protein coding RNA 473
chr11_+_101785727 0.11 ENST00000263468.8
KIAA1377
chr3_-_107777208 0.11 ENST00000398258.3
CD47 molecule
chr19_-_39735646 0.11 ENST00000413851.2
interferon, lambda 3
chr1_-_40237020 0.11 ENST00000327582.5
3-oxoacid CoA transferase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of MAF_NRL

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0072738 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.1 0.4 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.4 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.1 0.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.2 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.1 0.2 GO:0035910 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.4 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.1 0.2 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.1 0.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.3 GO:0010847 regulation of chromatin assembly(GO:0010847) protein auto-ADP-ribosylation(GO:0070213)
0.1 0.2 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.2 GO:1903939 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.0 0.1 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.0 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.1 GO:0071288 cellular response to mercury ion(GO:0071288) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.2 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.3 GO:1903786 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.1 GO:0033967 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.3 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.2 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.0 0.1 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.8 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.3 GO:0014820 tonic smooth muscle contraction(GO:0014820)
0.0 0.1 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.0 0.2 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.0 0.1 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.0 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.4 GO:1901166 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.0 0.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.6 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.1 GO:0010728 positive regulation of hydrogen peroxide metabolic process(GO:0010726) regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.0 0.1 GO:1902362 melanocyte proliferation(GO:0097325) melanocyte apoptotic process(GO:1902362)
0.0 0.1 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.3 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.2 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.2 GO:0045007 depurination(GO:0045007)
0.0 0.1 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.3 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.1 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.0 0.1 GO:0002588 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.0 0.1 GO:0048627 myoblast development(GO:0048627)
0.0 0.1 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0060667 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.0 0.5 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:0060381 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.0 0.0 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.0 GO:0019516 lactate oxidation(GO:0019516)
0.0 0.2 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.1 GO:0003335 corneocyte development(GO:0003335)
0.0 0.0 GO:1902566 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) regulation of eosinophil activation(GO:1902566) positive regulation of eosinophil activation(GO:1902568)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.0 GO:0061193 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.0 0.1 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.0 0.0 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.0 0.1 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.1 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:1902462 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.4 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.1 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.1 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.1 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.3 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.0 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.1 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.0 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 0.0 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.0 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.4 GO:0007398 ectoderm development(GO:0007398)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.0 GO:1903035 negative regulation of response to wounding(GO:1903035)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0043260 laminin-11 complex(GO:0043260)
0.1 0.3 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.4 GO:0035976 AP1 complex(GO:0035976)
0.0 0.1 GO:0030689 Noc complex(GO:0030689)
0.0 0.1 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.0 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.4 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.2 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0097196 Shu complex(GO:0097196)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004766 spermidine synthase activity(GO:0004766)
0.1 0.3 GO:1990175 EH domain binding(GO:1990175)
0.1 0.2 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.1 0.2 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.1 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.1 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.0 0.1 GO:0086040 sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086040)
0.0 0.4 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.1 GO:0019961 interferon binding(GO:0019961)
0.0 0.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.2 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0031433 telethonin binding(GO:0031433)
0.0 0.1 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0032090 Pyrin domain binding(GO:0032090)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0004040 amidase activity(GO:0004040)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.1 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.0 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.6 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.1 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.4 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.0 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.0 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor