ISMARA results: LHX6

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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for LHX6

Z-value: 0.81

Motif logo

Transcription factors associated with LHX6

Gene Symbol	Gene ID	Gene Info
LHX6 Ensembl NCBI GeneCards UniProt	ENSG00000106852.11	LIM homeobox 6

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
LHX6	hg19_v2_chr9_-_124990680_124990719	-0.60	2.1e-01	Click!

Activity profile of LHX6 motif

Sorted Z-values of LHX6 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr7_+_37723336 Show fit	1.56	ENST00000450180.1	GPR141 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 141
chr16_-_55866997 Show fit	0.77	ENST00000360526.3 ENST00000361503.4	CES1 Ensembl NCBI GeneCards UniProt Show fit	carboxylesterase 1
chr19_+_36239576 Show fit	0.73	ENST00000587751.1	LIN37 Ensembl NCBI GeneCards UniProt Show fit	lin-37 homolog (C. elegans)
chr2_+_113763031 Show fit	0.53	ENST00000259211.6	IL36A Ensembl NCBI GeneCards UniProt Show fit	interleukin 36, alpha
chr7_+_63505799 Show fit	0.46	ENST00000550760.3	ZNF727 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 727
chr6_-_30685214 Show fit	0.41	ENST00000425072.1	MDC1 Ensembl NCBI GeneCards UniProt Show fit	mediator of DNA-damage checkpoint 1
chr12_-_102133191 Show fit	0.40	ENST00000392924.1 ENST00000266743.2 ENST00000392927.3	SYCP3 Ensembl NCBI GeneCards UniProt Show fit	synaptonemal complex protein 3
chr6_-_30684898 Show fit	0.39	ENST00000422266.1 ENST00000416571.1	MDC1 Ensembl NCBI GeneCards UniProt Show fit	mediator of DNA-damage checkpoint 1
chr19_-_52307357 Show fit	0.35	ENST00000594900.1	FPR1 Ensembl NCBI GeneCards UniProt Show fit	formyl peptide receptor 1
chr10_-_99205607 Show fit	0.34	ENST00000477692.2 ENST00000485122.2 ENST00000370886.5 ENST00000370885.4 ENST00000370902.3 ENST00000370884.5	EXOSC1 Ensembl NCBI GeneCards UniProt Show fit	exosome component 1
chr13_-_81801115 Show fit	0.33	ENST00000567258.1	LINC00564 Ensembl NCBI GeneCards UniProt Show fit	long intergenic non-protein coding RNA 564
chr16_-_55867146 Show fit	0.33	ENST00000422046.2	CES1 Ensembl NCBI GeneCards UniProt Show fit	carboxylesterase 1
chr11_-_102668879 Show fit	0.30	ENST00000315274.6	MMP1 Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 1 (interstitial collagenase)
chr5_-_147286065 Show fit	0.30	ENST00000318315.4 ENST00000515291.1	C5orf46 Ensembl NCBI GeneCards UniProt Show fit	chromosome 5 open reading frame 46
chr1_-_152386732 Show fit	0.29	ENST00000271835.3	CRNN Ensembl NCBI GeneCards UniProt Show fit	cornulin
chr6_-_167040693 Show fit	0.28	ENST00000366863.2	RPS6KA2 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr11_-_102651343 Show fit	0.28	ENST00000279441.4 ENST00000539681.1	MMP10 Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 10 (stromelysin 2)
chr6_+_30687978 Show fit	0.27	ENST00000327892.8 ENST00000435534.1	TUBB Ensembl NCBI GeneCards UniProt Show fit	tubulin, beta class I
chr1_-_173886491 Show fit	0.26	ENST00000367698.3	SERPINC1 Ensembl NCBI GeneCards UniProt Show fit	serpin peptidase inhibitor, clade C (antithrombin), member 1
chr1_+_152943122 Show fit	0.25	ENST00000328051.2	SPRR4 Ensembl NCBI GeneCards UniProt Show fit	small proline-rich protein 4
chr16_+_31724618 Show fit	0.25	ENST00000530881.1 ENST00000529515.1	ZNF720 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 720
chr19_-_54663473 Show fit	0.24	ENST00000222224.3	LENG1 Ensembl NCBI GeneCards UniProt Show fit	leukocyte receptor cluster (LRC) member 1
chr5_+_66300446 Show fit	0.24	ENST00000261569.7	MAST4 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated serine/threonine kinase family member 4
chr14_+_100842735 Show fit	0.24	ENST00000554998.1 ENST00000402312.3 ENST00000335290.6 ENST00000554175.1	WDR25 Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 25
chr18_-_67624412 Show fit	0.23	ENST00000580335.1	CD226 Ensembl NCBI GeneCards UniProt Show fit	CD226 molecule
chr17_-_73937028 Show fit	0.23	ENST00000586631.2	FBF1 Ensembl NCBI GeneCards UniProt Show fit	Fas (TNFRSF6) binding factor 1
chr14_+_66578299 Show fit	0.23	ENST00000554187.1 ENST00000556662.1 ENST00000556291.1 ENST00000557723.1 ENST00000557050.1	RP11-783L4.1 Ensembl NCBI GeneCards UniProt Show fit	RP11-783L4.1
chr5_+_66300464 Show fit	0.23	ENST00000436277.1	MAST4 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated serine/threonine kinase family member 4
chr20_+_32782375 Show fit	0.23	ENST00000568305.1	ASIP Ensembl NCBI GeneCards UniProt Show fit	agouti signaling protein
chr6_-_167040731 Show fit	0.22	ENST00000265678.4	RPS6KA2 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr11_-_76155618 Show fit	0.22	ENST00000530759.1	RP11-111M22.3 Ensembl NCBI GeneCards UniProt Show fit	RP11-111M22.3
chr20_+_5731083 Show fit	0.22	ENST00000445603.1 ENST00000442185.1	C20orf196 Ensembl NCBI GeneCards UniProt Show fit	chromosome 20 open reading frame 196
chr17_-_47841485 Show fit	0.21	ENST00000506156.1 ENST00000240364.2	FAM117A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 117, member A
chr1_-_43833628 Show fit	0.21	ENST00000413844.2 ENST00000372458.3	ELOVL1 Ensembl NCBI GeneCards UniProt Show fit	ELOVL fatty acid elongase 1
chr4_-_103749179 Show fit	0.20	ENST00000502690.1	UBE2D3 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin-conjugating enzyme E2D 3
chr19_-_12833361 Show fit	0.20	ENST00000592287.1	TNPO2 Ensembl NCBI GeneCards UniProt Show fit	transportin 2
chr18_+_5238549 Show fit	0.20	ENST00000580684.1	LINC00667 Ensembl NCBI GeneCards UniProt Show fit	long intergenic non-protein coding RNA 667
chr1_+_81106951 Show fit	0.20	ENST00000443565.1	RP5-887A10.1 Ensembl NCBI GeneCards UniProt Show fit	RP5-887A10.1
chr2_-_152118276 Show fit	0.19	ENST00000409092.1	RBM43 Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 43
chr11_-_102714534 Show fit	0.19	ENST00000299855.5	MMP3 Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr4_+_158493642 Show fit	0.19	ENST00000507108.1 ENST00000455598.1 ENST00000509450.1	RP11-364P22.1 Ensembl NCBI GeneCards UniProt Show fit	RP11-364P22.1
chr6_+_31126291 Show fit	0.18	ENST00000376257.3 ENST00000376255.4	TCF19 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 19
chr10_-_72142345 Show fit	0.18	ENST00000373224.1 ENST00000446961.1 ENST00000358141.2 ENST00000357631.2	LRRC20 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 20
chr12_-_91546926 Show fit	0.18	ENST00000550758.1	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chrX_-_24690771 Show fit	0.17	ENST00000379145.1	PCYT1B Ensembl NCBI GeneCards UniProt Show fit	phosphate cytidylyltransferase 1, choline, beta
chr22_-_42017021 Show fit	0.17	ENST00000263256.6	DESI1 Ensembl NCBI GeneCards UniProt Show fit	desumoylating isopeptidase 1
chr19_-_19302931 Show fit	0.17	ENST00000444486.3 ENST00000514819.3 ENST00000585679.1 ENST00000162023.5	MEF2BNB-MEF2B Ensembl NCBI GeneCards UniProt Show fit MEF2BNB Ensembl NCBI GeneCards UniProt Show fit MEF2B Ensembl NCBI GeneCards UniProt Show fit	MEF2BNB-MEF2B readthrough MEF2B neighbor myocyte enhancer factor 2B
chr16_-_66583994 Show fit	0.17	ENST00000564917.1	TK2 Ensembl NCBI GeneCards UniProt Show fit	thymidine kinase 2, mitochondrial
chr5_-_171881362 Show fit	0.17	ENST00000519643.1	SH3PXD2B Ensembl NCBI GeneCards UniProt Show fit	SH3 and PX domains 2B
chr17_-_72772462 Show fit	0.17	ENST00000582870.1 ENST00000581136.1 ENST00000357814.3 ENST00000579218.1 ENST00000583476.1 ENST00000580301.1 ENST00000583757.1 ENST00000582524.1	NAT9 Ensembl NCBI GeneCards UniProt Show fit	N-acetyltransferase 9 (GCN5-related, putative)
chr6_-_30585009 Show fit	0.17	ENST00000376511.2	PPP1R10 Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1, regulatory subunit 10
chr6_+_29691198 Show fit	0.16	ENST00000440587.2 ENST00000434407.2	HLA-F Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class I, F
chr17_+_37809333 Show fit	0.16	ENST00000443521.1	STARD3 Ensembl NCBI GeneCards UniProt Show fit	StAR-related lipid transfer (START) domain containing 3
chr20_+_18488137 Show fit	0.16	ENST00000450074.1 ENST00000262544.2 ENST00000336714.3 ENST00000377475.3	SEC23B Ensembl NCBI GeneCards UniProt Show fit	Sec23 homolog B (S. cerevisiae)
chr9_+_104296163 Show fit	0.16	ENST00000374819.2 ENST00000479306.1	RNF20 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 20, E3 ubiquitin protein ligase
chr6_+_160183492 Show fit	0.16	ENST00000541436.1	ACAT2 Ensembl NCBI GeneCards UniProt Show fit	acetyl-CoA acetyltransferase 2
chr11_+_5710919 Show fit	0.16	ENST00000379965.3 ENST00000425490.1	TRIM22 Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 22
chr19_-_42916499 Show fit	0.15	ENST00000601189.1 ENST00000599211.1	LIPE Ensembl NCBI GeneCards UniProt Show fit	lipase, hormone-sensitive
chr1_+_28261533 Show fit	0.15	ENST00000411604.1 ENST00000373888.4	SMPDL3B Ensembl NCBI GeneCards UniProt Show fit	sphingomyelin phosphodiesterase, acid-like 3B
chrX_+_19362011 Show fit	0.15	ENST00000379806.5 ENST00000545074.1 ENST00000540249.1 ENST00000423505.1 ENST00000417819.1 ENST00000422285.2 ENST00000355808.5 ENST00000379805.3	PDHA1 Ensembl NCBI GeneCards UniProt Show fit	pyruvate dehydrogenase (lipoamide) alpha 1
chr6_+_26183958 Show fit	0.15	ENST00000356530.3	HIST1H2BE Ensembl NCBI GeneCards UniProt Show fit	histone cluster 1, H2be
chr17_-_7167279 Show fit	0.15	ENST00000571932.2	CLDN7 Ensembl NCBI GeneCards UniProt Show fit	claudin 7
chr3_-_160823040 Show fit	0.15	ENST00000484127.1 ENST00000492353.1 ENST00000473142.1 ENST00000468268.1 ENST00000460353.1 ENST00000320474.4 ENST00000392781.2	B3GALNT1 Ensembl NCBI GeneCards UniProt Show fit	beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr7_-_14029515 Show fit	0.15	ENST00000430479.1 ENST00000405218.2 ENST00000343495.5	ETV1 Ensembl NCBI GeneCards UniProt Show fit	ets variant 1
chr6_-_62996066 Show fit	0.14	ENST00000281156.4	KHDRBS2 Ensembl NCBI GeneCards UniProt Show fit	KH domain containing, RNA binding, signal transduction associated 2
chr12_-_56753858 Show fit	0.14	ENST00000314128.4 ENST00000557235.1 ENST00000418572.2	STAT2 Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 2, 113kDa
chr4_-_19458597 Show fit	0.14	ENST00000505347.1	RP11-3J1.1 Ensembl NCBI GeneCards UniProt Show fit	RP11-3J1.1
chr11_-_33913708 Show fit	0.14	ENST00000257818.2	LMO2 Ensembl NCBI GeneCards UniProt Show fit	LIM domain only 2 (rhombotin-like 1)
chr11_+_67798090 Show fit	0.13	ENST00000313468.5	NDUFS8 Ensembl NCBI GeneCards UniProt Show fit	NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr14_-_100842588 Show fit	0.13	ENST00000556645.1 ENST00000556209.1 ENST00000556504.1 ENST00000556435.1 ENST00000554772.1 ENST00000553581.1 ENST00000553769.2 ENST00000554605.1 ENST00000557722.1 ENST00000553413.1 ENST00000553524.1 ENST00000358655.4	WARS Ensembl NCBI GeneCards UniProt Show fit	tryptophanyl-tRNA synthetase
chr4_-_171012844 Show fit	0.13	ENST00000502392.1	AADAT Ensembl NCBI GeneCards UniProt Show fit	aminoadipate aminotransferase
chr3_+_108541545 Show fit	0.13	ENST00000295756.6	TRAT1 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor associated transmembrane adaptor 1
chrM_+_10758 Show fit	0.12	ENST00000361381.2	MT-ND4 Ensembl NCBI GeneCards UniProt Show fit	mitochondrially encoded NADH dehydrogenase 4
chr6_-_6711235 Show fit	0.12	ENST00000432823.2	RP1-80N2.2 Ensembl NCBI GeneCards UniProt Show fit	RP1-80N2.2
chr10_-_104001231 Show fit	0.12	ENST00000370002.3	PITX3 Ensembl NCBI GeneCards UniProt Show fit	paired-like homeodomain 3
chr17_-_4871085 Show fit	0.12	ENST00000575142.1 ENST00000206020.3	SPAG7 Ensembl NCBI GeneCards UniProt Show fit	sperm associated antigen 7
chr7_-_72971934 Show fit	0.12	ENST00000411832.1	BCL7B Ensembl NCBI GeneCards UniProt Show fit	B-cell CLL/lymphoma 7B
chr6_-_85474219 Show fit	0.12	ENST00000369663.5	TBX18 Ensembl NCBI GeneCards UniProt Show fit	T-box 18
chr6_+_29691056 Show fit	0.11	ENST00000414333.1 ENST00000334668.4 ENST00000259951.7	HLA-F Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class I, F
chr6_-_110501200 Show fit	0.11	ENST00000392586.1 ENST00000419252.1 ENST00000392589.1 ENST00000392588.1 ENST00000359451.2	WASF1 Ensembl NCBI GeneCards UniProt Show fit	WAS protein family, member 1
chr5_+_154181816 Show fit	0.11	ENST00000518677.1	LARP1 Ensembl NCBI GeneCards UniProt Show fit	La ribonucleoprotein domain family, member 1
chr7_-_44613494 Show fit	0.11	ENST00000431640.1 ENST00000258772.5	DDX56 Ensembl NCBI GeneCards UniProt Show fit	DEAD (Asp-Glu-Ala-Asp) box helicase 56
chr10_+_97709725 Show fit	0.11	ENST00000472454.2	RP11-248J23.6 Ensembl NCBI GeneCards UniProt Show fit	Protein LOC100652732
chr1_+_100817262 Show fit	0.11	ENST00000455467.1	CDC14A Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 14A
chr9_+_34646651 Show fit	0.11	ENST00000378842.3	GALT Ensembl NCBI GeneCards UniProt Show fit	galactose-1-phosphate uridylyltransferase
chr16_-_66584059 Show fit	0.11	ENST00000417693.3 ENST00000544898.1 ENST00000569718.1 ENST00000527284.1 ENST00000299697.7 ENST00000451102.2	TK2 Ensembl NCBI GeneCards UniProt Show fit	thymidine kinase 2, mitochondrial
chr6_-_31125850 Show fit	0.11	ENST00000507751.1 ENST00000448162.2 ENST00000502557.1 ENST00000503420.1 ENST00000507892.1 ENST00000507226.1 ENST00000513222.1 ENST00000503934.1 ENST00000396263.2 ENST00000508683.1 ENST00000428174.1 ENST00000448141.2 ENST00000507829.1 ENST00000455279.2 ENST00000376266.5	CCHCR1 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil alpha-helical rod protein 1
chr18_-_67624160 Show fit	0.11	ENST00000581982.1 ENST00000280200.4	CD226 Ensembl NCBI GeneCards UniProt Show fit	CD226 molecule
chr15_-_44116873 Show fit	0.11	ENST00000267812.3	MFAP1 Ensembl NCBI GeneCards UniProt Show fit	microfibrillar-associated protein 1
chr11_+_57435219 Show fit	0.10	ENST00000527985.1 ENST00000287169.3	ZDHHC5 Ensembl NCBI GeneCards UniProt Show fit	zinc finger, DHHC-type containing 5
chr3_+_67705121 Show fit	0.10	ENST00000464420.1 ENST00000482677.1	RP11-81N13.1 Ensembl NCBI GeneCards UniProt Show fit	RP11-81N13.1
chr1_-_36906474 Show fit	0.10	ENST00000433045.2	OSCP1 Ensembl NCBI GeneCards UniProt Show fit	organic solute carrier partner 1
chr15_+_90118723 Show fit	0.10	ENST00000560985.1	TICRR Ensembl NCBI GeneCards UniProt Show fit	TOPBP1-interacting checkpoint and replication regulator
chr3_-_160823158 Show fit	0.10	ENST00000392779.2 ENST00000392780.1 ENST00000494173.1	B3GALNT1 Ensembl NCBI GeneCards UniProt Show fit	beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr4_+_89513574 Show fit	0.10	ENST00000402738.1 ENST00000431413.1 ENST00000422770.1 ENST00000407637.1	HERC3 Ensembl NCBI GeneCards UniProt Show fit	HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr7_-_151330218 Show fit	0.10	ENST00000476632.1	PRKAG2 Ensembl NCBI GeneCards UniProt Show fit	protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr10_+_124914285 Show fit	0.10	ENST00000407911.2	BUB3 Ensembl NCBI GeneCards UniProt Show fit	BUB3 mitotic checkpoint protein
chr20_-_50418972 Show fit	0.10	ENST00000395997.3	SALL4 Ensembl NCBI GeneCards UniProt Show fit	spalt-like transcription factor 4
chr4_+_155702496 Show fit	0.10	ENST00000510397.1	RBM46 Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 46
chr7_+_37723450 Show fit	0.10	ENST00000447769.1	GPR141 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 141
chr16_+_2479390 Show fit	0.10	ENST00000397066.4	CCNF Ensembl NCBI GeneCards UniProt Show fit	cyclin F
chr15_+_90118685 Show fit	0.10	ENST00000268138.7	TICRR Ensembl NCBI GeneCards UniProt Show fit	TOPBP1-interacting checkpoint and replication regulator
chr3_+_179280668 Show fit	0.09	ENST00000429709.2 ENST00000450518.2 ENST00000392662.1 ENST00000490364.1	ACTL6A Ensembl NCBI GeneCards UniProt Show fit	actin-like 6A
chr3_+_43020773 Show fit	0.09	ENST00000488863.1	FAM198A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 198, member A
chr9_+_34646624 Show fit	0.09	ENST00000450095.2 ENST00000556278.1	GALT Ensembl NCBI GeneCards UniProt Show fit GALT Ensembl NCBI GeneCards UniProt Show fit	galactose-1-phosphate uridylyltransferase Uncharacterized protein
chr3_+_85008089 Show fit	0.09	ENST00000383699.3	CADM2 Ensembl NCBI GeneCards UniProt Show fit	cell adhesion molecule 2
chr19_-_14889349 Show fit	0.09	ENST00000315576.3 ENST00000392967.2 ENST00000346057.1 ENST00000353876.1 ENST00000353005.1	EMR2 Ensembl NCBI GeneCards UniProt Show fit	egf-like module containing, mucin-like, hormone receptor-like 2
chr2_+_201936707 Show fit	0.09	ENST00000433898.1 ENST00000454214.1	NDUFB3 Ensembl NCBI GeneCards UniProt Show fit	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chrX_+_77154935 Show fit	0.09	ENST00000481445.1	COX7B Ensembl NCBI GeneCards UniProt Show fit	cytochrome c oxidase subunit VIIb
chr11_-_236326 Show fit	0.09	ENST00000525237.1 ENST00000532956.1 ENST00000525319.1 ENST00000524564.1 ENST00000382743.4	SIRT3 Ensembl NCBI GeneCards UniProt Show fit	sirtuin 3
chr17_-_62208169 Show fit	0.09	ENST00000606895.1	ERN1 Ensembl NCBI GeneCards UniProt Show fit	endoplasmic reticulum to nucleus signaling 1
chr9_+_117904097 Show fit	0.09	ENST00000374016.1	DEC1 Ensembl NCBI GeneCards UniProt Show fit	deleted in esophageal cancer 1
chr9_-_35103105 Show fit	0.09	ENST00000452248.2 ENST00000356493.5	STOML2 Ensembl NCBI GeneCards UniProt Show fit	stomatin (EPB72)-like 2
chr9_-_38424443 Show fit	0.09	ENST00000377694.1	IGFBPL1 Ensembl NCBI GeneCards UniProt Show fit	insulin-like growth factor binding protein-like 1
chr1_+_44115814 Show fit	0.09	ENST00000372396.3	KDM4A Ensembl NCBI GeneCards UniProt Show fit	lysine (K)-specific demethylase 4A
chr7_-_111424462 Show fit	0.09	ENST00000437129.1	DOCK4 Ensembl NCBI GeneCards UniProt Show fit	dedicator of cytokinesis 4
chr12_-_95611149 Show fit	0.09	ENST00000549499.1 ENST00000343958.4 ENST00000546711.1	FGD6 Ensembl NCBI GeneCards UniProt Show fit	FYVE, RhoGEF and PH domain containing 6
chr12_+_95611536 Show fit	0.09	ENST00000549002.1	VEZT Ensembl NCBI GeneCards UniProt Show fit	vezatin, adherens junctions transmembrane protein
chr19_-_12833164 Show fit	0.09	ENST00000356861.5	TNPO2 Ensembl NCBI GeneCards UniProt Show fit	transportin 2
chr9_+_12695702 Show fit	0.09	ENST00000381136.2	TYRP1 Ensembl NCBI GeneCards UniProt Show fit	tyrosinase-related protein 1
chr17_+_42148097 Show fit	0.09	ENST00000269097.4	G6PC3 Ensembl NCBI GeneCards UniProt Show fit	glucose 6 phosphatase, catalytic, 3
chr3_-_47018219 Show fit	0.09	ENST00000292314.2 ENST00000546280.1	CCDC12 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 12
chr20_-_54967187 Show fit	0.08	ENST00000422322.1 ENST00000371356.2 ENST00000451915.1 ENST00000347343.2 ENST00000395911.1 ENST00000395907.1 ENST00000441357.1 ENST00000456249.1 ENST00000420474.1 ENST00000395909.4 ENST00000395914.1 ENST00000312783.6 ENST00000395915.3 ENST00000395913.3	AURKA Ensembl NCBI GeneCards UniProt Show fit	aurora kinase A
chr20_+_30467600 Show fit	0.08	ENST00000375934.4 ENST00000375922.4	TTLL9 Ensembl NCBI GeneCards UniProt Show fit	tubulin tyrosine ligase-like family, member 9
chr13_-_46626820 Show fit	0.08	ENST00000428921.1	ZC3H13 Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCCH-type containing 13
chr3_+_156009623 Show fit	0.08	ENST00000389634.5	KCNAB1 Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr3_+_9439400 Show fit	0.08	ENST00000450326.1 ENST00000402198.1 ENST00000402466.1	SETD5 Ensembl NCBI GeneCards UniProt Show fit	SET domain containing 5
chr17_+_73452695 Show fit	0.08	ENST00000582186.1 ENST00000582455.1 ENST00000581252.1 ENST00000579208.1	KIAA0195 Ensembl NCBI GeneCards UniProt Show fit	KIAA0195
chr18_+_5238055 Show fit	0.08	ENST00000582363.1 ENST00000582008.1 ENST00000580082.1	LINC00667 Ensembl NCBI GeneCards UniProt Show fit	long intergenic non-protein coding RNA 667
chr17_+_42786051 Show fit	0.08	ENST00000315005.3	DBF4B Ensembl NCBI GeneCards UniProt Show fit	DBF4 homolog B (S. cerevisiae)
chr2_+_166095898 Show fit	0.08	ENST00000424833.1 ENST00000375437.2 ENST00000357398.3	SCN2A Ensembl NCBI GeneCards UniProt Show fit	sodium channel, voltage-gated, type II, alpha subunit
chr19_-_10491234 Show fit	0.08	ENST00000524462.1 ENST00000531836.1 ENST00000525621.1	TYK2 Ensembl NCBI GeneCards UniProt Show fit	tyrosine kinase 2
chr5_-_162887071 Show fit	0.08	ENST00000302764.4	NUDCD2 Ensembl NCBI GeneCards UniProt Show fit	NudC domain containing 2
chr12_+_95611569 Show fit	0.08	ENST00000261219.6 ENST00000551472.1 ENST00000552821.1	VEZT Ensembl NCBI GeneCards UniProt Show fit	vezatin, adherens junctions transmembrane protein
chr4_-_138453606 Show fit	0.08	ENST00000412923.2 ENST00000344876.4 ENST00000507846.1 ENST00000510305.1	PCDH18 Ensembl NCBI GeneCards UniProt Show fit	protocadherin 18
chr17_-_40337470 Show fit	0.08	ENST00000293330.1	HCRT Ensembl NCBI GeneCards UniProt Show fit	hypocretin (orexin) neuropeptide precursor
chr11_+_67798114 Show fit	0.08	ENST00000453471.2 ENST00000528492.1 ENST00000526339.1 ENST00000525419.1	NDUFS8 Ensembl NCBI GeneCards UniProt Show fit	NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr16_+_12059091 Show fit	0.08	ENST00000562385.1	TNFRSF17 Ensembl NCBI GeneCards UniProt Show fit	tumor necrosis factor receptor superfamily, member 17
chr22_-_17640110 Show fit	0.08	ENST00000399852.3 ENST00000336737.4	CECR5 Ensembl NCBI GeneCards UniProt Show fit	cat eye syndrome chromosome region, candidate 5
chr10_+_124913930 Show fit	0.08	ENST00000368858.5	BUB3 Ensembl NCBI GeneCards UniProt Show fit	BUB3 mitotic checkpoint protein
chr4_+_15376165 Show fit	0.08	ENST00000382383.3 ENST00000429690.1	C1QTNF7 Ensembl NCBI GeneCards UniProt Show fit	C1q and tumor necrosis factor related protein 7
chr1_-_205819245 Show fit	0.08	ENST00000367136.4	PM20D1 Ensembl NCBI GeneCards UniProt Show fit	peptidase M20 domain containing 1
chr21_-_22175341 Show fit	0.08	ENST00000416768.1 ENST00000452561.1 ENST00000419299.1 ENST00000437238.1	LINC00320 Ensembl NCBI GeneCards UniProt Show fit	long intergenic non-protein coding RNA 320
chr7_-_87342564 Show fit	0.08	ENST00000265724.3 ENST00000416177.1	ABCB1 Ensembl NCBI GeneCards UniProt Show fit	ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr11_+_17298342 Show fit	0.08	ENST00000530964.1	NUCB2 Ensembl NCBI GeneCards UniProt Show fit	nucleobindin 2
chr17_+_12569472 Show fit	0.08	ENST00000343344.4	MYOCD Ensembl NCBI GeneCards UniProt Show fit	myocardin
chr17_+_74261413 Show fit	0.08	ENST00000587913.1	UBALD2 Ensembl NCBI GeneCards UniProt Show fit	UBA-like domain containing 2
chr19_+_41869894 Show fit	0.07	ENST00000413014.2	TMEM91 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 91
chr17_+_80416482 Show fit	0.07	ENST00000309794.11 ENST00000345415.7 ENST00000457415.3 ENST00000584411.1 ENST00000412079.2 ENST00000577432.1	NARF Ensembl NCBI GeneCards UniProt Show fit	nuclear prelamin A recognition factor
chr4_-_174255400 Show fit	0.07	ENST00000506267.1	HMGB2 Ensembl NCBI GeneCards UniProt Show fit	high mobility group box 2
chr11_-_18548426 Show fit	0.07	ENST00000357193.3 ENST00000536719.1	TSG101 Ensembl NCBI GeneCards UniProt Show fit	tumor susceptibility 101
chr19_-_11266437 Show fit	0.07	ENST00000586708.1 ENST00000591396.1 ENST00000592967.1 ENST00000585486.1 ENST00000585567.1	SPC24 Ensembl NCBI GeneCards UniProt Show fit	SPC24, NDC80 kinetochore complex component
chr4_+_74275057 Show fit	0.07	ENST00000511370.1	ALB Ensembl NCBI GeneCards UniProt Show fit	albumin
chr14_+_99947715 Show fit	0.07	ENST00000389879.5 ENST00000557441.1 ENST00000555049.1 ENST00000555842.1	CCNK Ensembl NCBI GeneCards UniProt Show fit	cyclin K
chr16_+_29817399 Show fit	0.07	ENST00000545521.1	MAZ Ensembl NCBI GeneCards UniProt Show fit	MYC-associated zinc finger protein (purine-binding transcription factor)
chr12_-_5352315 Show fit	0.07	ENST00000536518.1	RP11-319E16.1 Ensembl NCBI GeneCards UniProt Show fit	RP11-319E16.1
chr12_-_49075941 Show fit	0.07	ENST00000553086.1 ENST00000548304.1	KANSL2 Ensembl NCBI GeneCards UniProt Show fit	KAT8 regulatory NSL complex subunit 2
chr1_+_151735431 Show fit	0.07	ENST00000321531.5 ENST00000315067.8	OAZ3 Ensembl NCBI GeneCards UniProt Show fit	ornithine decarboxylase antizyme 3
chr6_+_53948328 Show fit	0.07	ENST00000370876.2	MLIP Ensembl NCBI GeneCards UniProt Show fit	muscular LMNA-interacting protein
chr21_-_22175450 Show fit	0.07	ENST00000435279.2	LINC00320 Ensembl NCBI GeneCards UniProt Show fit	long intergenic non-protein coding RNA 320
chr14_+_104182061 Show fit	0.07	ENST00000216602.6	ZFYVE21 Ensembl NCBI GeneCards UniProt Show fit	zinc finger, FYVE domain containing 21
chr3_-_157221128 Show fit	0.07	ENST00000392833.2 ENST00000362010.2	VEPH1 Ensembl NCBI GeneCards UniProt Show fit	ventricular zone expressed PH domain-containing 1
chr3_-_53164423 Show fit	0.07	ENST00000467048.1 ENST00000394738.3 ENST00000296292.3	RFT1 Ensembl NCBI GeneCards UniProt Show fit	RFT1 homolog (S. cerevisiae)
chr14_-_104181771 Show fit	0.07	ENST00000554913.1 ENST00000554974.1 ENST00000553361.1 ENST00000555055.1 ENST00000555964.1 ENST00000556682.1 ENST00000445556.1 ENST00000553332.1 ENST00000352127.7	XRCC3 Ensembl NCBI GeneCards UniProt Show fit	X-ray repair complementing defective repair in Chinese hamster cells 3
chr16_-_66583701 Show fit	0.07	ENST00000527800.1 ENST00000525974.1 ENST00000563369.2	TK2 Ensembl NCBI GeneCards UniProt Show fit	thymidine kinase 2, mitochondrial
chr14_+_104182105 Show fit	0.07	ENST00000311141.2	ZFYVE21 Ensembl NCBI GeneCards UniProt Show fit	zinc finger, FYVE domain containing 21
chr3_+_9439579 Show fit	0.07	ENST00000406341.1	SETD5 Ensembl NCBI GeneCards UniProt Show fit	SET domain containing 5
chr4_+_178649911 Show fit	0.07	ENST00000507870.1	RP11-389E17.1 Ensembl NCBI GeneCards UniProt Show fit	long intergenic non-protein coding RNA 1098
chr5_-_20575959 Show fit	0.06	ENST00000507958.1	CDH18 Ensembl NCBI GeneCards UniProt Show fit	cadherin 18, type 2
chr17_+_72772621 Show fit	0.06	ENST00000335464.5 ENST00000417024.2 ENST00000578764.1 ENST00000582773.1 ENST00000582330.1	TMEM104 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 104
chr3_+_63805017 Show fit	0.06	ENST00000295896.8	C3orf49 Ensembl NCBI GeneCards UniProt Show fit	chromosome 3 open reading frame 49
chr19_-_7694417 Show fit	0.06	ENST00000358368.4 ENST00000534844.1	XAB2 Ensembl NCBI GeneCards UniProt Show fit	XPA binding protein 2
chr13_+_37006421 Show fit	0.06	ENST00000255465.4	CCNA1 Ensembl NCBI GeneCards UniProt Show fit	cyclin A1
chr14_+_21249200 Show fit	0.06	ENST00000304677.2	RNASE6 Ensembl NCBI GeneCards UniProt Show fit	ribonuclease, RNase A family, k6
chr17_-_47045949 Show fit	0.06	ENST00000357424.2	GIP Ensembl NCBI GeneCards UniProt Show fit	gastric inhibitory polypeptide
chr12_+_95611516 Show fit	0.06	ENST00000436874.1	VEZT Ensembl NCBI GeneCards UniProt Show fit	vezatin, adherens junctions transmembrane protein
chr17_+_66511540 Show fit	0.06	ENST00000588188.2	PRKAR1A Ensembl NCBI GeneCards UniProt Show fit	protein kinase, cAMP-dependent, regulatory, type I, alpha
chr20_+_35807512 Show fit	0.06	ENST00000373622.5	RPN2 Ensembl NCBI GeneCards UniProt Show fit	ribophorin II
chr18_+_616672 Show fit	0.06	ENST00000338387.7	CLUL1 Ensembl NCBI GeneCards UniProt Show fit	clusterin-like 1 (retinal)
chr19_+_7694623 Show fit	0.06	ENST00000594797.1 ENST00000456958.3 ENST00000601406.1	PET100 Ensembl NCBI GeneCards UniProt Show fit	PET100 homolog (S. cerevisiae)
chr19_-_10491130 Show fit	0.06	ENST00000530829.1 ENST00000529370.1	TYK2 Ensembl NCBI GeneCards UniProt Show fit	tyrosine kinase 2
chr3_-_42003613 Show fit	0.06	ENST00000414606.1	ULK4 Ensembl NCBI GeneCards UniProt Show fit	unc-51 like kinase 4
chr1_-_1709845 Show fit	0.06	ENST00000341426.5 ENST00000344463.4	NADK Ensembl NCBI GeneCards UniProt Show fit	NAD kinase
chr6_-_33385655 Show fit	0.06	ENST00000440279.3 ENST00000607266.1	CUTA Ensembl NCBI GeneCards UniProt Show fit	cutA divalent cation tolerance homolog (E. coli)
chr13_+_37006398 Show fit	0.06	ENST00000418263.1	CCNA1 Ensembl NCBI GeneCards UniProt Show fit	cyclin A1
chr10_+_13141441 Show fit	0.06	ENST00000263036.5	OPTN Ensembl NCBI GeneCards UniProt Show fit	optineurin
chr10_+_99205894 Show fit	0.06	ENST00000370854.3 ENST00000393760.1 ENST00000414567.1 ENST00000370846.4	ZDHHC16 Ensembl NCBI GeneCards UniProt Show fit	zinc finger, DHHC-type containing 16
chr14_+_74034310 Show fit	0.06	ENST00000538782.1	ACOT2 Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA thioesterase 2
chr7_-_127983877 Show fit	0.06	ENST00000415472.2 ENST00000478061.1 ENST00000223073.2 ENST00000459726.1	RBM28 Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 28
chr20_-_50419055 Show fit	0.06	ENST00000217086.4	SALL4 Ensembl NCBI GeneCards UniProt Show fit	spalt-like transcription factor 4
chr17_-_1531635 Show fit	0.06	ENST00000571650.1	SLC43A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 43 (amino acid system L transporter), member 2
chr17_-_38210644 Show fit	0.06	ENST00000394128.2 ENST00000394127.2 ENST00000356271.3 ENST00000535071.2 ENST00000580885.1 ENST00000543759.2 ENST00000537674.2 ENST00000580517.1 ENST00000578161.1	MED24 Ensembl NCBI GeneCards UniProt Show fit	mediator complex subunit 24
chr16_+_15744078 Show fit	0.06	ENST00000396354.1 ENST00000570727.1	NDE1 Ensembl NCBI GeneCards UniProt Show fit	nudE neurodevelopment protein 1
chr7_-_140714739 Show fit	0.06	ENST00000467334.1 ENST00000324787.5	MRPS33 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein S33
chr12_-_45270077 Show fit	0.06	ENST00000551601.1 ENST00000549027.1 ENST00000452445.2	NELL2 Ensembl NCBI GeneCards UniProt Show fit	NEL-like 2 (chicken)
chr8_-_7220490 Show fit	0.06	ENST00000400078.2	ZNF705G Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 705G
chr6_+_29624758 Show fit	0.06	ENST00000376917.3 ENST00000376902.3 ENST00000533330.2 ENST00000376888.2	MOG Ensembl NCBI GeneCards UniProt Show fit	myelin oligodendrocyte glycoprotein
chr9_+_1050331 Show fit	0.06	ENST00000382255.3 ENST00000382251.3 ENST00000412350.2	DMRT2 Ensembl NCBI GeneCards UniProt Show fit	doublesex and mab-3 related transcription factor 2
chr21_+_35014783 Show fit	0.06	ENST00000381291.4 ENST00000381285.4 ENST00000399367.3 ENST00000399352.1 ENST00000399355.2 ENST00000399349.1	ITSN1 Ensembl NCBI GeneCards UniProt Show fit	intersectin 1 (SH3 domain protein)
chr2_-_74618964 Show fit	0.06	ENST00000417090.1 ENST00000409868.1	DCTN1 Ensembl NCBI GeneCards UniProt Show fit	dynactin 1

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX6

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.1	GO:0090119	vesicle-mediated cholesterol transport(GO:0090119)
0.1	0.3	GO:0046092	deoxycytidine metabolic process(GO:0046092)
0.1	0.2	GO:0006258	UDP-glucose catabolic process(GO:0006258)
0.1	0.4	GO:0002729	positive regulation of natural killer cell cytokine production(GO:0002729)
0.0	0.4	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0	0.1	GO:0060827	regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.0	0.8	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.0	0.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560) positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.0	0.2	GO:0046340	diacylglycerol catabolic process(GO:0046340)
0.0	0.2	GO:0033512	L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0	0.1	GO:1901860	positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.0	0.1	GO:0043438	acetoacetic acid metabolic process(GO:0043438)
0.0	0.2	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.1	GO:0007057	spindle assembly involved in female meiosis I(GO:0007057)
0.0	0.3	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0	0.1	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.0	0.1	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.0	0.2	GO:1904179	positive regulation of adipose tissue development(GO:1904179)
0.0	0.2	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.0	0.1	GO:2000395	positive regulation of viral budding via host ESCRT complex(GO:1903774) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0	0.1	GO:0044179	hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0	0.1	GO:1904933	regulation of cell proliferation in midbrain(GO:1904933)
0.0	0.3	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.1	GO:0071139	resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0	0.2	GO:2001166	regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0	0.1	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0	0.2	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.1	GO:0000349	generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.0	0.2	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.2	GO:0010727	negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0	0.1	GO:0072752	cellular response to rapamycin(GO:0072752)
0.0	0.0	GO:0046901	tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.0	0.3	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.2	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0	0.0	GO:0072356	chromosome passenger complex localization to kinetochore(GO:0072356)
0.0	0.2	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.1	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.0	0.3	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:2000275	regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.0	0.2	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0	0.1	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.2	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.1	GO:1901142	insulin metabolic process(GO:1901142)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0033597	mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.0	0.2	GO:0030936	collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0	0.2	GO:0097123	cyclin A1-CDK2 complex(GO:0097123)
0.0	0.3	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.1	GO:0002944	cyclin K-CDK12 complex(GO:0002944) cyclin K-CDK13 complex(GO:0002945)
0.0	0.3	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.2	GO:0033503	HULC complex(GO:0033503)
0.0	0.1	GO:0042585	germinal vesicle(GO:0042585)
0.0	0.1	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0	0.4	GO:0000800	lateral element(GO:0000800)
0.0	0.3	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.2	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.2	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.0	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	0.2	GO:0097539	ciliary transition fiber(GO:0097539)
0.0	0.1	GO:1990635	proximal dendrite(GO:1990635)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.1	GO:0047374	methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1	0.2	GO:0047273	galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1	0.3	GO:0004137	deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1	0.2	GO:0033878	hormone-sensitive lipase activity(GO:0033878)
0.1	0.2	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.3	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.1	GO:0047536	2-aminoadipate transaminase activity(GO:0047536)
0.0	0.3	GO:0046979	TAP2 binding(GO:0046979)
0.0	0.2	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0	0.2	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0	0.1	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0	0.1	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.2	GO:0031779	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.5	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.0	0.1	GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.0	0.0	GO:0004326	tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.1	GO:0090554	phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0	0.2	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.0	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.3	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)

Gene overrepresentation in C2:CP category:

Total log-likelihood	Term	Description
1.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.8	PID ATM PATHWAY	ATM pathway
0.8	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.3	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.8	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.3	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.8	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.3	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.7	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.3	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.3	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling

Results for LHX6

Z-value: 0.81

Motif logo

Transcription factors associated with LHX6

Activity-expression correlation:

Activity profile of LHX6 motif

Sorted Z-values of LHX6 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX6

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: