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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for KLF3

Z-value: 1.32

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Transcription factors associated with KLF3

Gene Symbol Gene ID Gene Info
KLF3
ENSG00000109787.8 Kruppel like factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF3hg19_v2_chr4_+_38665810_38665827-0.522.9e-01Click!

Activity profile of KLF3 motif

Sorted Z-values of KLF3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_38171681 2.64 ENST00000225474.2
ENST00000331769.2
ENST00000394148.3
ENST00000577675.1
CSF3
colony stimulating factor 3 (granulocyte)
chr6_+_43968306 1.58 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223
chromosome 6 open reading frame 223
chr17_+_38171614 1.46 ENST00000583218.1
ENST00000394149.3
CSF3
colony stimulating factor 3 (granulocyte)
chr20_+_44637526 1.33 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr12_+_113344811 0.90 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr15_+_42565393 0.86 ENST00000561871.1
GANC
glucosidase, alpha; neutral C
chr20_+_43803517 0.84 ENST00000243924.3
PI3
peptidase inhibitor 3, skin-derived
chr5_+_148443049 0.79 ENST00000515304.1
ENST00000507318.1
CTC-529P8.1
CTC-529P8.1
chr19_-_10227503 0.74 ENST00000593054.1
EIF3G
eukaryotic translation initiation factor 3, subunit G
chr2_+_37571717 0.73 ENST00000338415.3
ENST00000404976.1
QPCT
glutaminyl-peptide cyclotransferase
chr11_+_118826999 0.73 ENST00000264031.2
UPK2
uroplakin 2
chr6_+_144471643 0.67 ENST00000367568.4
STX11
syntaxin 11
chr16_+_2079501 0.66 ENST00000563587.1
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr1_+_96208646 0.64 ENST00000603401.1
RP11-286B14.2
RP11-286B14.2
chr19_-_44174330 0.61 ENST00000340093.3
PLAUR
plasminogen activator, urokinase receptor
chr19_+_40873617 0.60 ENST00000599353.1
PLD3
phospholipase D family, member 3
chr12_+_7169887 0.56 ENST00000542978.1
C1S
complement component 1, s subcomponent
chr6_-_133035185 0.54 ENST00000367928.4
VNN1
vanin 1
chr16_+_89989687 0.53 ENST00000315491.7
ENST00000555576.1
ENST00000554336.1
ENST00000553967.1
TUBB3
Tubulin beta-3 chain
chr11_-_60010556 0.52 ENST00000427611.2
MS4A4E
membrane-spanning 4-domains, subfamily A, member 4E
chr1_+_1846519 0.52 ENST00000378604.3
CALML6
calmodulin-like 6
chr19_-_42927251 0.51 ENST00000597001.1
LIPE
lipase, hormone-sensitive
chr1_-_155112883 0.51 ENST00000368399.1
ENST00000368400.4
ENST00000341298.3
DPM3
dolichyl-phosphate mannosyltransferase polypeptide 3
chr17_+_6939362 0.49 ENST00000308027.6
SLC16A13
solute carrier family 16, member 13
chr18_+_61554932 0.48 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr22_-_50970566 0.47 ENST00000405135.1
ENST00000401779.1
ODF3B
outer dense fiber of sperm tails 3B
chr17_+_73750699 0.46 ENST00000584939.1
ITGB4
integrin, beta 4
chr19_-_44174305 0.46 ENST00000601723.1
ENST00000339082.3
PLAUR
plasminogen activator, urokinase receptor
chr8_+_145734433 0.45 ENST00000301327.4
MFSD3
major facilitator superfamily domain containing 3
chr1_+_44457261 0.45 ENST00000372318.3
CCDC24
coiled-coil domain containing 24
chr17_-_62207485 0.44 ENST00000433197.3
ERN1
endoplasmic reticulum to nucleus signaling 1
chr17_+_47210125 0.43 ENST00000393354.2
B4GALNT2
beta-1,4-N-acetyl-galactosaminyl transferase 2
chr2_+_37571845 0.43 ENST00000537448.1
QPCT
glutaminyl-peptide cyclotransferase
chr11_-_61659006 0.43 ENST00000278829.2
FADS3
fatty acid desaturase 3
chr15_+_96897466 0.42 ENST00000558382.1
ENST00000558499.1
RP11-522B15.3
RP11-522B15.3
chr11_+_60691924 0.42 ENST00000544065.1
ENST00000453848.2
ENST00000005286.4
TMEM132A
transmembrane protein 132A
chr22_+_39868786 0.42 ENST00000429402.1
MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr3_+_157261116 0.42 ENST00000468043.1
ENST00000459838.1
ENST00000461040.1
ENST00000449199.2
ENST00000426338.2
C3orf55
chromosome 3 open reading frame 55
chr17_+_73996987 0.42 ENST00000588812.1
ENST00000448471.1
CDK3
cyclin-dependent kinase 3
chr11_+_64052692 0.41 ENST00000377702.4
GPR137
G protein-coupled receptor 137
chr11_-_61658853 0.41 ENST00000525588.1
ENST00000540820.1
FADS3
fatty acid desaturase 3
chr16_-_3086927 0.41 ENST00000572449.1
CCDC64B
coiled-coil domain containing 64B
chr16_-_1843694 0.41 ENST00000569769.1
SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr3_-_4793274 0.41 ENST00000414938.1
EGOT
eosinophil granule ontogeny transcript (non-protein coding)
chr8_-_145060593 0.40 ENST00000313059.5
ENST00000524918.1
ENST00000313028.7
ENST00000525773.1
PARP10
poly (ADP-ribose) polymerase family, member 10
chr11_-_67205538 0.40 ENST00000326294.3
PTPRCAP
protein tyrosine phosphatase, receptor type, C-associated protein
chr12_+_7072354 0.39 ENST00000537269.1
U47924.27
U47924.27
chr13_-_111214015 0.38 ENST00000267328.3
RAB20
RAB20, member RAS oncogene family
chr11_+_65383227 0.38 ENST00000355703.3
PCNXL3
pecanex-like 3 (Drosophila)
chr18_+_42277095 0.38 ENST00000591940.1
SETBP1
SET binding protein 1
chr1_-_209792111 0.38 ENST00000455193.1
LAMB3
laminin, beta 3
chr7_+_73245193 0.37 ENST00000340958.2
CLDN4
claudin 4
chr22_-_50970506 0.37 ENST00000428989.2
ENST00000403326.1
ODF3B
outer dense fiber of sperm tails 3B
chr1_+_44457441 0.37 ENST00000466180.1
CCDC24
coiled-coil domain containing 24
chr16_-_57837129 0.37 ENST00000562984.1
ENST00000564891.1
KIFC3
kinesin family member C3
chr15_+_75074915 0.37 ENST00000567123.1
ENST00000569462.1
CSK
c-src tyrosine kinase
chr8_-_145642267 0.37 ENST00000301305.3
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr17_-_39928106 0.37 ENST00000540235.1
JUP
junction plakoglobin
chr7_+_76139741 0.37 ENST00000334348.3
ENST00000419923.2
ENST00000448265.3
ENST00000443097.2
UPK3B
uroplakin 3B
chrX_-_48326764 0.36 ENST00000413668.1
ENST00000441948.1
SLC38A5
solute carrier family 38, member 5
chr8_-_144699628 0.35 ENST00000529048.1
ENST00000529064.1
TSTA3
tissue specific transplantation antigen P35B
chr19_+_45251804 0.35 ENST00000164227.5
BCL3
B-cell CLL/lymphoma 3
chr5_-_90610200 0.35 ENST00000511918.1
ENST00000513626.1
ENST00000607854.1
LUCAT1
RP11-213H15.4
lung cancer associated transcript 1 (non-protein coding)
RP11-213H15.4
chr11_+_844067 0.35 ENST00000397406.1
ENST00000409543.2
ENST00000525201.1
TSPAN4
tetraspanin 4
chr15_-_41522889 0.35 ENST00000458580.2
ENST00000314992.5
ENST00000558396.1
EXD1
exonuclease 3'-5' domain containing 1
chr10_-_75385711 0.35 ENST00000433394.1
USP54
ubiquitin specific peptidase 54
chr19_-_51529849 0.35 ENST00000600362.1
ENST00000453757.3
ENST00000601671.1
KLK11
kallikrein-related peptidase 11
chr9_-_34665983 0.34 ENST00000416454.1
ENST00000544078.2
ENST00000421828.2
ENST00000423809.1
RP11-195F19.5
HCG2040265, isoform CRA_a; Uncharacterized protein; cDNA FLJ50015
chr12_+_122326630 0.34 ENST00000541212.1
ENST00000340175.5
PSMD9
proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
chr8_-_144897549 0.34 ENST00000356994.2
ENST00000320476.3
SCRIB
scribbled planar cell polarity protein
chr16_-_57831914 0.34 ENST00000421376.2
KIFC3
kinesin family member C3
chr14_-_24733444 0.34 ENST00000560478.1
ENST00000560443.1
TGM1
transglutaminase 1
chr19_+_19303008 0.33 ENST00000353145.1
ENST00000421262.3
ENST00000303088.4
ENST00000456252.3
ENST00000593273.1
RFXANK
regulatory factor X-associated ankyrin-containing protein
chr22_+_38071615 0.33 ENST00000215909.5
LGALS1
lectin, galactoside-binding, soluble, 1
chr11_+_844406 0.33 ENST00000397404.1
TSPAN4
tetraspanin 4
chr1_+_200638629 0.33 ENST00000568695.1
RP11-92G12.3
RP11-92G12.3
chr16_+_67195004 0.33 ENST00000523893.1
FBXL8
F-box and leucine-rich repeat protein 8
chr1_-_63782888 0.32 ENST00000436475.2
LINC00466
long intergenic non-protein coding RNA 466
chr8_-_23712312 0.32 ENST00000290271.2
STC1
stanniocalcin 1
chr15_-_74495188 0.32 ENST00000563965.1
ENST00000395105.4
STRA6
stimulated by retinoic acid 6
chr20_+_34204939 0.32 ENST00000454819.1
SPAG4
sperm associated antigen 4
chr16_+_2083265 0.32 ENST00000565855.1
ENST00000566198.1
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr22_-_31536480 0.32 ENST00000215885.3
PLA2G3
phospholipase A2, group III
chr4_+_84457250 0.31 ENST00000395226.2
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr19_+_8429031 0.31 ENST00000301455.2
ENST00000541807.1
ENST00000393962.2
ANGPTL4
angiopoietin-like 4
chr11_-_65429891 0.31 ENST00000527874.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr19_-_1132207 0.31 ENST00000438103.2
SBNO2
strawberry notch homolog 2 (Drosophila)
chr1_-_27286897 0.31 ENST00000320567.5
C1orf172
chromosome 1 open reading frame 172
chr4_-_155511887 0.31 ENST00000302053.3
ENST00000403106.3
FGA
fibrinogen alpha chain
chr16_+_67233412 0.31 ENST00000477898.1
ELMO3
engulfment and cell motility 3
chr22_-_36850991 0.29 ENST00000442579.1
RP5-1119A7.14
RP5-1119A7.14
chr15_+_90792760 0.29 ENST00000339615.5
ENST00000438251.1
TTLL13
tubulin tyrosine ligase-like family, member 13
chr19_+_1941117 0.29 ENST00000255641.8
CSNK1G2
casein kinase 1, gamma 2
chr8_+_145582633 0.29 ENST00000540505.1
SLC52A2
solute carrier family 52 (riboflavin transporter), member 2
chr16_+_58033450 0.29 ENST00000561743.1
USB1
U6 snRNA biogenesis 1
chr4_+_84457529 0.29 ENST00000264409.4
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr17_+_38119216 0.29 ENST00000301659.4
GSDMA
gasdermin A
chr17_-_39928501 0.28 ENST00000420370.1
JUP
junction plakoglobin
chr19_-_4722705 0.28 ENST00000598360.1
DPP9
dipeptidyl-peptidase 9
chr8_-_123793048 0.28 ENST00000607710.1
RP11-44N11.2
RP11-44N11.2
chr15_-_85197501 0.28 ENST00000434634.2
WDR73
WD repeat domain 73
chr5_+_170210721 0.28 ENST00000265294.4
ENST00000519385.1
ENST00000519598.1
GABRP
gamma-aminobutyric acid (GABA) A receptor, pi
chr8_-_145013711 0.28 ENST00000345136.3
PLEC
plectin
chr17_+_1633755 0.27 ENST00000545662.1
WDR81
WD repeat domain 81
chrX_+_23685653 0.27 ENST00000379331.3
PRDX4
peroxiredoxin 4
chr17_+_18128896 0.27 ENST00000316843.4
LLGL1
lethal giant larvae homolog 1 (Drosophila)
chr17_+_40118805 0.27 ENST00000591072.1
ENST00000587679.1
ENST00000393888.1
ENST00000441615.2
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr22_+_20119320 0.27 ENST00000334554.7
ENST00000320602.7
ENST00000405930.3
ZDHHC8
zinc finger, DHHC-type containing 8
chr17_+_34312621 0.27 ENST00000591669.1
CTB-186H2.3
Uncharacterized protein
chr19_-_40324767 0.27 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
DYRK1B
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr19_-_51523275 0.26 ENST00000309958.3
KLK10
kallikrein-related peptidase 10
chr19_+_14017116 0.26 ENST00000589606.1
CC2D1A
coiled-coil and C2 domain containing 1A
chr3_-_5229982 0.26 ENST00000600805.1
AC026202.1
Uncharacterized protein
chr9_+_107526443 0.26 ENST00000374762.3
NIPSNAP3B
nipsnap homolog 3B (C. elegans)
chr19_+_19303572 0.26 ENST00000407360.3
ENST00000540981.1
RFXANK
regulatory factor X-associated ankyrin-containing protein
chr15_+_75074410 0.26 ENST00000439220.2
CSK
c-src tyrosine kinase
chr20_+_55966444 0.26 ENST00000356208.5
ENST00000440234.2
RBM38
RNA binding motif protein 38
chr19_-_19302931 0.26 ENST00000444486.3
ENST00000514819.3
ENST00000585679.1
ENST00000162023.5
MEF2BNB-MEF2B
MEF2BNB
MEF2B
MEF2BNB-MEF2B readthrough
MEF2B neighbor
myocyte enhancer factor 2B
chr16_+_31483451 0.26 ENST00000565360.1
ENST00000361773.3
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr19_+_39897943 0.25 ENST00000600033.1
ZFP36
ZFP36 ring finger protein
chr10_-_102289611 0.25 ENST00000299166.4
ENST00000370320.4
ENST00000531258.1
ENST00000370322.1
ENST00000535773.1
NDUFB8
SEC31B
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
SEC31 homolog B (S. cerevisiae)
chr7_-_752577 0.25 ENST00000544935.1
ENST00000430040.1
ENST00000456696.2
ENST00000406797.1
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr19_+_16308711 0.25 ENST00000429941.2
ENST00000444449.2
ENST00000589822.1
AP1M1
adaptor-related protein complex 1, mu 1 subunit
chr17_+_36873677 0.25 ENST00000471200.1
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr16_-_79804198 0.25 ENST00000568389.1
RP11-345M22.2
RP11-345M22.2
chr3_-_49203744 0.25 ENST00000321895.6
CCDC71
coiled-coil domain containing 71
chr7_+_872107 0.24 ENST00000405266.1
ENST00000401592.1
ENST00000403868.1
ENST00000425407.2
SUN1
Sad1 and UNC84 domain containing 1
chr11_+_119038897 0.24 ENST00000454811.1
ENST00000449394.1
NLRX1
NLR family member X1
chr18_-_61329118 0.24 ENST00000332821.8
ENST00000283752.5
SERPINB3
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr16_-_57831676 0.24 ENST00000465878.2
ENST00000539578.1
ENST00000561524.1
KIFC3
kinesin family member C3
chr17_+_73997419 0.24 ENST00000425876.2
CDK3
cyclin-dependent kinase 3
chr15_+_67430339 0.24 ENST00000439724.3
SMAD3
SMAD family member 3
chr17_+_40118773 0.24 ENST00000472031.1
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chrX_+_70364667 0.24 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
NLGN3
neuroligin 3
chr11_-_72433346 0.24 ENST00000334211.8
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr19_+_17448348 0.24 ENST00000324894.8
ENST00000358792.7
ENST00000600625.1
GTPBP3
GTP binding protein 3 (mitochondrial)
chr7_+_870547 0.23 ENST00000457598.1
SUN1
Sad1 and UNC84 domain containing 1
chr8_-_145018080 0.23 ENST00000354589.3
PLEC
plectin
chr22_-_36635225 0.23 ENST00000529194.1
APOL2
apolipoprotein L, 2
chr2_+_85132749 0.23 ENST00000233143.4
TMSB10
thymosin beta 10
chr2_+_219187871 0.23 ENST00000258362.3
PNKD
paroxysmal nonkinesigenic dyskinesia
chr11_-_68039364 0.23 ENST00000533310.1
ENST00000304271.6
ENST00000527280.1
C11orf24
chromosome 11 open reading frame 24
chr11_-_441964 0.23 ENST00000332826.6
ANO9
anoctamin 9
chr16_-_57513657 0.23 ENST00000566936.1
ENST00000568617.1
ENST00000567276.1
ENST00000569548.1
ENST00000569250.1
ENST00000564378.1
DOK4
docking protein 4
chr17_+_4699439 0.22 ENST00000270586.3
PSMB6
proteasome (prosome, macropain) subunit, beta type, 6
chrX_+_133941218 0.22 ENST00000370784.4
ENST00000370785.3
FAM122C
family with sequence similarity 122C
chr19_+_35630344 0.22 ENST00000455515.2
FXYD1
FXYD domain containing ion transport regulator 1
chr19_-_2739992 0.22 ENST00000545664.1
ENST00000589363.1
ENST00000455372.2
SLC39A3
solute carrier family 39 (zinc transporter), member 3
chr20_+_3776936 0.22 ENST00000439880.2
CDC25B
cell division cycle 25B
chrX_-_153141302 0.22 ENST00000361699.4
ENST00000543994.1
ENST00000370057.3
ENST00000538883.1
ENST00000361981.3
L1CAM
L1 cell adhesion molecule
chr16_+_30077055 0.22 ENST00000564595.2
ENST00000569798.1
ALDOA
aldolase A, fructose-bisphosphate
chr19_+_16308659 0.22 ENST00000590263.1
ENST00000590756.1
ENST00000541844.1
AP1M1
adaptor-related protein complex 1, mu 1 subunit
chr11_+_59705928 0.22 ENST00000398992.1
OOSP1
oocyte secreted protein 1
chr7_+_65670186 0.21 ENST00000304842.5
ENST00000442120.1
TPST1
tyrosylprotein sulfotransferase 1
chr14_-_24711470 0.21 ENST00000559969.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr1_-_206671061 0.21 ENST00000367119.1
C1orf147
chromosome 1 open reading frame 147
chr1_-_24126051 0.21 ENST00000445705.1
GALE
UDP-galactose-4-epimerase
chr1_-_6445809 0.21 ENST00000377855.2
ACOT7
acyl-CoA thioesterase 7
chr14_-_24711865 0.21 ENST00000399423.4
ENST00000267415.7
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr12_+_120502441 0.21 ENST00000446727.2
CCDC64
coiled-coil domain containing 64
chr11_-_65626753 0.21 ENST00000526975.1
ENST00000531413.1
CFL1
cofilin 1 (non-muscle)
chr3_-_50383096 0.21 ENST00000442887.1
ENST00000360165.3
ZMYND10
zinc finger, MYND-type containing 10
chr14_+_77647966 0.20 ENST00000554766.1
TMEM63C
transmembrane protein 63C
chr19_+_50919056 0.20 ENST00000599632.1
CTD-2545M3.6
CTD-2545M3.6
chr1_+_13910757 0.20 ENST00000376061.4
ENST00000513143.1
PDPN
podoplanin
chr11_+_68816356 0.20 ENST00000294309.3
ENST00000542467.1
TPCN2
two pore segment channel 2
chr3_+_75713481 0.20 ENST00000308062.3
ENST00000464571.1
FRG2C
FSHD region gene 2 family, member C
chr11_-_57194948 0.20 ENST00000533235.1
ENST00000526621.1
ENST00000352187.1
SLC43A3
solute carrier family 43, member 3
chr20_+_3777078 0.20 ENST00000340833.4
CDC25B
cell division cycle 25B
chr11_-_65430251 0.19 ENST00000534283.1
ENST00000527749.1
ENST00000533187.1
ENST00000525693.1
ENST00000534558.1
ENST00000532879.1
ENST00000532999.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr9_+_140149625 0.19 ENST00000343053.4
NELFB
negative elongation factor complex member B
chr7_+_34697846 0.19 ENST00000381553.3
ENST00000465305.1
ENST00000360581.1
ENST00000381542.1
ENST00000359791.1
ENST00000531252.1
NPSR1
neuropeptide S receptor 1
chr16_-_67514982 0.19 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
ATP6V0D1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr19_-_51523412 0.19 ENST00000391805.1
ENST00000599077.1
KLK10
kallikrein-related peptidase 10
chr1_+_67773527 0.19 ENST00000541374.1
ENST00000544434.1
IL12RB2
interleukin 12 receptor, beta 2
chr21_-_47613673 0.19 ENST00000594486.1
AP001468.1
Protein LOC101060037
chr15_+_75074385 0.19 ENST00000220003.9
CSK
c-src tyrosine kinase
chr19_-_4722780 0.19 ENST00000600621.1
DPP9
dipeptidyl-peptidase 9
chr20_+_31499459 0.19 ENST00000439060.1
EFCAB8
EF-hand calcium binding domain 8
chr7_+_76139833 0.19 ENST00000257632.5
UPK3B
uroplakin 3B
chr16_+_8715536 0.19 ENST00000563958.1
ENST00000381920.3
ENST00000564554.1
METTL22
methyltransferase like 22
chr16_+_84209738 0.19 ENST00000564928.1
DNAAF1
dynein, axonemal, assembly factor 1
chr22_-_51017084 0.19 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr17_-_39968855 0.19 ENST00000355468.3
ENST00000590496.1
LEPREL4
leprecan-like 4
chr20_+_62666902 0.19 ENST00000431158.1
LINC00176
long intergenic non-protein coding RNA 176
chr1_+_17914907 0.19 ENST00000375420.3
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr19_+_676385 0.19 ENST00000166139.4
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr3_+_51976338 0.19 ENST00000417220.2
ENST00000431474.1
ENST00000398755.3
PARP3
poly (ADP-ribose) polymerase family, member 3
chr19_+_12902289 0.18 ENST00000302754.4
JUNB
jun B proto-oncogene
chrX_+_140096761 0.18 ENST00000370530.1
SPANXB1
SPANX family, member B1
chr7_-_2272566 0.18 ENST00000402746.1
ENST00000265854.7
ENST00000429779.1
ENST00000399654.2
MAD1L1
MAD1 mitotic arrest deficient-like 1 (yeast)
chr5_+_140501581 0.18 ENST00000194152.1
PCDHB4
protocadherin beta 4
chr1_-_9189144 0.18 ENST00000414642.2
GPR157
G protein-coupled receptor 157
chr11_-_72432950 0.18 ENST00000426523.1
ENST00000429686.1
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr1_-_22215192 0.18 ENST00000374673.3
HSPG2
heparan sulfate proteoglycan 2
chr2_-_26205340 0.18 ENST00000264712.3
KIF3C
kinesin family member 3C
chr7_+_100466433 0.18 ENST00000429658.1
TRIP6
thyroid hormone receptor interactor 6
chr12_+_52404270 0.18 ENST00000552049.1
ENST00000546756.1
GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chrX_-_71526999 0.18 ENST00000453707.2
ENST00000373619.3
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr19_-_51466681 0.18 ENST00000456750.2
KLK6
kallikrein-related peptidase 6

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.3 4.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.2 0.6 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.2 2.5 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.1 0.8 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 0.4 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.1 0.3 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.1 1.0 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.9 GO:0000023 maltose metabolic process(GO:0000023)
0.1 0.5 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.7 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 0.4 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 0.7 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.1 0.4 GO:0042351 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.1 0.4 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.4 GO:0010847 regulation of chromatin assembly(GO:0010847) protein auto-ADP-ribosylation(GO:0070213)
0.1 0.3 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 0.3 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.1 0.2 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.2 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.1 0.7 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.1 0.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.4 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.3 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.2 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.5 GO:1901142 insulin metabolic process(GO:1901142)
0.1 0.2 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.2 GO:0071258 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.1 0.3 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.1 0.3 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.1 GO:1904666 regulation of ubiquitin protein ligase activity(GO:1904666) positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.3 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 0.2 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.2 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.3 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.0 0.3 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.2 GO:0060024 rhythmic synaptic transmission(GO:0060024) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.2 GO:0060611 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) positive regulation of microglial cell migration(GO:1904141)
0.0 0.2 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 0.8 GO:0007620 copulation(GO:0007620)
0.0 0.5 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.3 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.4 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.2 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.5 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.2 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.4 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276) lipid glycosylation(GO:0030259)
0.0 0.1 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.1 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.0 0.1 GO:0090034 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846) regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.0 1.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.5 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.2 GO:0040038 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.5 GO:0007144 female meiosis I(GO:0007144)
0.0 0.6 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.3 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0 0.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.3 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.2 GO:0051510 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.1 GO:2001176 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.0 0.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.0 0.1 GO:0048627 myoblast development(GO:0048627)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.5 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.4 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.2 GO:1902231 positive regulation of keratinocyte apoptotic process(GO:1902174) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.1 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.4 GO:0015816 glycine transport(GO:0015816)
0.0 0.3 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.2 GO:0071926 endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.4 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.1 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.2 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 0.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.2 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.5 GO:0048757 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.3 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.0 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.5 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.1 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.1 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.0 0.1 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.3 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.2 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.1 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.1 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.0 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.0 GO:0002763 positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.0 0.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.3 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.2 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.0 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.0 0.4 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.8 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.0 GO:0060988 lipid tube assembly(GO:0060988)
0.0 0.1 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.7 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.1 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.2 GO:0046951 ketone body biosynthetic process(GO:0046951)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.2 0.7 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.2 0.3 GO:1990923 PET complex(GO:1990923)
0.1 0.5 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.7 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.1 0.5 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.4 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 1.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 1.0 GO:0005915 zonula adherens(GO:0005915)
0.0 0.7 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.2 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 1.0 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.4 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.1 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 2.8 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.7 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.6 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 1.2 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.4 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.2 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.0 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.2 0.5 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.2 0.7 GO:0005199 structural constituent of cell wall(GO:0005199)
0.2 0.6 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.2 1.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.1 0.5 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.4 GO:0042356 GDP-4-dehydro-D-rhamnose reductase activity(GO:0042356) GDP-L-fucose synthase activity(GO:0050577)
0.1 0.5 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.9 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558) maltose alpha-glucosidase activity(GO:0032450)
0.1 0.4 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.3 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.1 0.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.3 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.6 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.2 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.0 0.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.3 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 1.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 1.0 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.5 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.0 0.3 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.8 GO:0043495 protein anchor(GO:0043495)
0.0 0.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.5 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 4.6 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 0.1 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.3 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.1 GO:0016499 orexin receptor activity(GO:0016499)
0.0 0.1 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505) 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.2 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.3 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 3.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.7 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.0 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.1 GO:0048185 activin binding(GO:0048185)
0.0 0.0 GO:0002054 nucleobase binding(GO:0002054)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.7 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.7 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.6 ST GAQ PATHWAY G alpha q Pathway
0.0 0.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 1.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.8 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.5 REACTOME HEMOSTASIS Genes involved in Hemostasis
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.5 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.1 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 2.0 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway