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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for KLF15

Z-value: 1.03

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Transcription factors associated with KLF15

Gene Symbol Gene ID Gene Info
KLF15
ENSG00000163884.3 Kruppel like factor 15

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF15hg19_v2_chr3_-_126076264_126076305-0.786.9e-02Click!

Activity profile of KLF15 motif

Sorted Z-values of KLF15 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_48757278 0.73 ENST00000404752.1
ENST00000406226.1
STON1
stonin 1
chr10_+_35416223 0.62 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr3_-_185826718 0.55 ENST00000413301.1
ENST00000421809.1
ETV5
ets variant 5
chr14_-_65439132 0.55 ENST00000533601.2
RAB15
RAB15, member RAS oncogene family
chr10_+_112631699 0.49 ENST00000444997.1
PDCD4
programmed cell death 4 (neoplastic transformation inhibitor)
chr10_-_22292675 0.49 ENST00000376946.1
DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr5_+_61601965 0.45 ENST00000401507.3
KIF2A
kinesin heavy chain member 2A
chr5_+_61602055 0.45 ENST00000381103.2
KIF2A
kinesin heavy chain member 2A
chr11_-_46142615 0.43 ENST00000529734.1
ENST00000323180.6
PHF21A
PHD finger protein 21A
chr5_+_61602236 0.43 ENST00000514082.1
ENST00000407818.3
KIF2A
kinesin heavy chain member 2A
chr7_+_74379083 0.42 ENST00000361825.7
GATSL1
GATS protein-like 1
chr22_+_29469100 0.40 ENST00000327813.5
ENST00000407188.1
KREMEN1
kringle containing transmembrane protein 1
chr13_-_45151259 0.39 ENST00000493016.1
TSC22D1
TSC22 domain family, member 1
chr12_-_123215306 0.37 ENST00000356987.2
ENST00000436083.2
HCAR1
hydroxycarboxylic acid receptor 1
chr10_+_112631547 0.37 ENST00000280154.7
ENST00000393104.2
PDCD4
programmed cell death 4 (neoplastic transformation inhibitor)
chr14_+_32546274 0.37 ENST00000396582.2
ARHGAP5
Rho GTPase activating protein 5
chr14_+_32546145 0.36 ENST00000556611.1
ENST00000539826.2
ARHGAP5
Rho GTPase activating protein 5
chr11_+_1874200 0.31 ENST00000311604.3
LSP1
lymphocyte-specific protein 1
chr14_-_65438865 0.30 ENST00000267512.5
RAB15
RAB15, member RAS oncogene family
chr1_-_8763278 0.30 ENST00000468247.1
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr6_-_18264406 0.27 ENST00000515742.1
DEK
DEK oncogene
chr15_+_76352178 0.27 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr14_-_36990061 0.27 ENST00000546983.1
NKX2-1
NK2 homeobox 1
chr7_+_94285637 0.27 ENST00000482108.1
ENST00000488574.1
PEG10
paternally expressed 10
chr4_+_39640787 0.26 ENST00000532680.1
RP11-539G18.2
RP11-539G18.2
chr6_-_143832793 0.26 ENST00000438118.2
FUCA2
fucosidase, alpha-L- 2, plasma
chr6_+_149068464 0.25 ENST00000367463.4
UST
uronyl-2-sulfotransferase
chr19_-_47975106 0.25 ENST00000539381.1
ENST00000594353.1
ENST00000542837.1
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr12_+_26274917 0.25 ENST00000538142.1
SSPN
sarcospan
chr10_+_21823079 0.25 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr17_+_55334364 0.24 ENST00000322684.3
ENST00000579590.1
MSI2
musashi RNA-binding protein 2
chr9_-_6015607 0.24 ENST00000259569.5
RANBP6
RAN binding protein 6
chr13_-_52026730 0.24 ENST00000420668.2
INTS6
integrator complex subunit 6
chr21_-_27107283 0.23 ENST00000284971.3
ENST00000400099.1
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr1_+_198126209 0.22 ENST00000367383.1
NEK7
NIMA-related kinase 7
chr7_-_99869799 0.22 ENST00000436886.2
GATS
GATS, stromal antigen 3 opposite strand
chr21_+_27107672 0.21 ENST00000400075.3
GABPA
GA binding protein transcription factor, alpha subunit 60kDa
chr6_-_18264706 0.21 ENST00000244776.7
ENST00000503715.1
DEK
DEK oncogene
chr5_-_111093081 0.21 ENST00000453526.2
ENST00000509427.1
NREP
neuronal regeneration related protein
chr14_+_32546485 0.21 ENST00000345122.3
ENST00000432921.1
ENST00000433497.1
ARHGAP5
Rho GTPase activating protein 5
chr7_-_143059780 0.21 ENST00000409578.1
ENST00000409346.1
FAM131B
family with sequence similarity 131, member B
chr19_-_49565254 0.21 ENST00000593537.1
NTF4
neurotrophin 4
chr18_-_45935663 0.21 ENST00000589194.1
ENST00000591279.1
ENST00000590855.1
ENST00000587107.1
ENST00000588970.1
ENST00000586525.1
ENST00000592387.1
ENST00000590800.1
ZBTB7C
zinc finger and BTB domain containing 7C
chr18_-_21977748 0.20 ENST00000399441.4
ENST00000319481.3
OSBPL1A
oxysterol binding protein-like 1A
chr12_+_57853918 0.20 ENST00000532291.1
ENST00000543426.1
ENST00000228682.2
ENST00000546141.1
GLI1
GLI family zinc finger 1
chr2_+_242254753 0.20 ENST00000428524.1
ENST00000445030.1
ENST00000407017.1
SEPT2
septin 2
chr17_-_19290483 0.20 ENST00000395592.2
ENST00000299610.4
MFAP4
microfibrillar-associated protein 4
chr8_-_22014255 0.20 ENST00000424267.2
LGI3
leucine-rich repeat LGI family, member 3
chr11_+_22646739 0.20 ENST00000428556.2
AC103801.2
AC103801.2
chr11_-_46142505 0.20 ENST00000524497.1
ENST00000418153.2
PHF21A
PHD finger protein 21A
chr9_+_86595626 0.20 ENST00000445877.1
ENST00000325875.3
RMI1
RecQ mediated genome instability 1
chr12_-_48213735 0.20 ENST00000417902.1
ENST00000417107.1
HDAC7
histone deacetylase 7
chrX_-_48693955 0.20 ENST00000218230.5
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr9_-_84303269 0.20 ENST00000418319.1
TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr5_+_42423872 0.20 ENST00000230882.4
ENST00000357703.3
GHR
growth hormone receptor
chr9_+_2621950 0.20 ENST00000382096.1
VLDLR
very low density lipoprotein receptor
chr16_+_29817841 0.19 ENST00000322945.6
ENST00000562337.1
ENST00000566906.2
ENST00000563402.1
ENST00000219782.6
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr6_+_32936942 0.19 ENST00000496118.2
BRD2
bromodomain containing 2
chr20_+_48909240 0.19 ENST00000371639.3
RP11-290F20.1
RP11-290F20.1
chr3_+_37903432 0.19 ENST00000443503.2
CTDSPL
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr1_+_33283043 0.19 ENST00000373476.1
ENST00000373475.5
ENST00000529027.1
ENST00000398243.3
S100PBP
S100P binding protein
chr13_-_49107205 0.19 ENST00000544904.1
ENST00000430805.2
ENST00000544492.1
RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr10_+_21823243 0.19 ENST00000307729.7
ENST00000377091.2
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr10_-_25012115 0.19 ENST00000446003.1
ARHGAP21
Rho GTPase activating protein 21
chr2_+_242254679 0.18 ENST00000428282.1
ENST00000360051.3
SEPT2
septin 2
chr12_+_57522692 0.18 ENST00000554174.1
LRP1
low density lipoprotein receptor-related protein 1
chr6_-_18265050 0.18 ENST00000397239.3
DEK
DEK oncogene
chr3_+_195943369 0.18 ENST00000296327.5
SLC51A
solute carrier family 51, alpha subunit
chr10_-_15210615 0.18 ENST00000378150.1
NMT2
N-myristoyltransferase 2
chr17_-_41984835 0.17 ENST00000520406.1
ENST00000518478.1
ENST00000522172.1
ENST00000461854.1
ENST00000521178.1
ENST00000520305.1
ENST00000523501.1
ENST00000520241.1
MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr17_-_15168624 0.17 ENST00000312280.3
ENST00000494511.1
ENST00000580584.1
PMP22
peripheral myelin protein 22
chr18_-_51750948 0.17 ENST00000583046.1
ENST00000398398.2
MBD2
methyl-CpG binding domain protein 2
chr9_+_125703282 0.17 ENST00000373647.4
ENST00000402311.1
RABGAP1
RAB GTPase activating protein 1
chr19_+_18284477 0.17 ENST00000407280.3
IFI30
interferon, gamma-inducible protein 30
chr3_-_149293990 0.17 ENST00000472417.1
WWTR1
WW domain containing transcription regulator 1
chr19_-_55866061 0.17 ENST00000588572.2
ENST00000593184.1
ENST00000589467.1
COX6B2
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr1_+_206680879 0.16 ENST00000355294.4
ENST00000367117.3
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr15_-_79237433 0.16 ENST00000220166.5
CTSH
cathepsin H
chr4_-_170947446 0.16 ENST00000507601.1
ENST00000512698.1
MFAP3L
microfibrillar-associated protein 3-like
chr11_-_46142948 0.16 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr19_-_14049184 0.16 ENST00000339560.5
PODNL1
podocan-like 1
chr21_-_27107344 0.16 ENST00000457143.2
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr11_-_82782861 0.16 ENST00000524635.1
ENST00000526205.1
ENST00000527633.1
ENST00000533486.1
ENST00000533276.2
RAB30
RAB30, member RAS oncogene family
chr2_-_233792837 0.16 ENST00000373552.4
ENST00000409079.1
NGEF
neuronal guanine nucleotide exchange factor
chr7_-_94285472 0.16 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
SGCE
sarcoglycan, epsilon
chr19_+_1354930 0.16 ENST00000591337.1
MUM1
melanoma associated antigen (mutated) 1
chr7_-_150675372 0.16 ENST00000262186.5
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr13_+_25670268 0.16 ENST00000281589.3
PABPC3
poly(A) binding protein, cytoplasmic 3
chr1_-_85666688 0.15 ENST00000341460.5
SYDE2
synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
chr21_-_27107198 0.15 ENST00000400094.1
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr6_-_74231303 0.15 ENST00000309268.6
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr12_+_19282643 0.15 ENST00000317589.4
ENST00000355397.3
ENST00000359180.3
ENST00000309364.4
ENST00000540972.1
ENST00000429027.2
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr10_-_129924611 0.15 ENST00000368654.3
MKI67
marker of proliferation Ki-67
chr7_-_94285511 0.15 ENST00000265735.7
SGCE
sarcoglycan, epsilon
chr19_+_11039391 0.15 ENST00000270502.6
C19orf52
chromosome 19 open reading frame 52
chr22_+_22673051 0.15 ENST00000390289.2
IGLV5-52
immunoglobulin lambda variable 5-52
chr2_+_242254507 0.15 ENST00000391973.2
SEPT2
septin 2
chr7_+_116139744 0.15 ENST00000343213.2
CAV2
caveolin 2
chr8_+_38758845 0.15 ENST00000519640.1
PLEKHA2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr7_-_98030360 0.15 ENST00000005260.8
BAIAP2L1
BAI1-associated protein 2-like 1
chr19_-_47975417 0.15 ENST00000236877.6
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr9_+_101867387 0.15 ENST00000374990.2
ENST00000552516.1
TGFBR1
transforming growth factor, beta receptor 1
chr7_-_28220354 0.15 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr18_-_57364588 0.15 ENST00000439986.4
CCBE1
collagen and calcium binding EGF domains 1
chr10_+_35415851 0.15 ENST00000374726.3
CREM
cAMP responsive element modulator
chr10_-_79397547 0.15 ENST00000481070.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr3_+_9851558 0.15 ENST00000430718.1
TTLL3
tubulin tyrosine ligase-like family, member 3
chr16_+_23847339 0.15 ENST00000303531.7
PRKCB
protein kinase C, beta
chr11_-_77531858 0.14 ENST00000360355.2
RSF1
remodeling and spacing factor 1
chr1_-_40367668 0.14 ENST00000397332.2
ENST00000429311.1
MYCL
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr12_+_53443963 0.14 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr17_-_41985096 0.14 ENST00000269095.4
ENST00000523220.1
MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chrX_+_16737718 0.14 ENST00000380155.3
SYAP1
synapse associated protein 1
chr6_+_24495067 0.14 ENST00000357578.3
ENST00000546278.1
ENST00000491546.1
ALDH5A1
aldehyde dehydrogenase 5 family, member A1
chr2_-_160472052 0.14 ENST00000437839.1
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr17_+_77681075 0.14 ENST00000397549.2
CTD-2116F7.1
CTD-2116F7.1
chr13_-_51101468 0.14 ENST00000428276.1
RP11-175B12.2
RP11-175B12.2
chr7_-_92157760 0.14 ENST00000248633.4
PEX1
peroxisomal biogenesis factor 1
chr11_-_62457371 0.14 ENST00000317449.4
LRRN4CL
LRRN4 C-terminal like
chr2_+_242255275 0.14 ENST00000391971.2
SEPT2
septin 2
chr16_+_30418910 0.13 ENST00000566625.1
ZNF771
zinc finger protein 771
chr3_+_9851384 0.13 ENST00000419081.1
ENST00000438596.1
ENST00000417065.1
ENST00000439814.1
ENST00000418745.1
TTLL3
tubulin tyrosine ligase-like family, member 3
chr5_-_137071756 0.13 ENST00000394937.3
ENST00000309755.4
KLHL3
kelch-like family member 3
chr7_-_92157747 0.13 ENST00000428214.1
ENST00000438045.1
PEX1
peroxisomal biogenesis factor 1
chr3_-_188665428 0.13 ENST00000444488.1
TPRG1-AS1
TPRG1 antisense RNA 1
chr17_-_46178527 0.13 ENST00000393408.3
CBX1
chromobox homolog 1
chr3_+_12838161 0.13 ENST00000456430.2
CAND2
cullin-associated and neddylation-dissociated 2 (putative)
chr11_-_110167352 0.13 ENST00000533991.1
ENST00000528498.1
ENST00000405097.1
ENST00000528900.1
ENST00000530301.1
ENST00000343115.4
RDX
radixin
chr15_+_40544749 0.13 ENST00000559617.1
ENST00000560684.1
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr18_+_74207477 0.13 ENST00000532511.1
RP11-17M16.1
uncharacterized protein LOC400658
chr12_+_53491220 0.13 ENST00000548547.1
ENST00000301464.3
IGFBP6
insulin-like growth factor binding protein 6
chr7_-_100493744 0.13 ENST00000428317.1
ENST00000441605.1
ACHE
acetylcholinesterase (Yt blood group)
chr19_+_589893 0.13 ENST00000251287.2
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr21_-_40720995 0.13 ENST00000380749.5
HMGN1
high mobility group nucleosome binding domain 1
chr8_+_109455830 0.13 ENST00000524143.1
EMC2
ER membrane protein complex subunit 2
chr7_-_155160629 0.13 ENST00000378120.5
BLACE
B-cell acute lymphoblastic leukemia expressed
chr2_+_97481974 0.13 ENST00000377060.3
ENST00000305510.3
CNNM3
cyclin M3
chr11_-_110167331 0.13 ENST00000534683.1
RDX
radixin
chr6_-_74230741 0.12 ENST00000316292.9
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr14_+_59655369 0.12 ENST00000360909.3
ENST00000351081.1
ENST00000556135.1
DAAM1
dishevelled associated activator of morphogenesis 1
chr11_-_102323740 0.12 ENST00000398136.2
TMEM123
transmembrane protein 123
chr3_-_149688502 0.12 ENST00000481767.1
ENST00000475518.1
PFN2
profilin 2
chr11_-_82782952 0.12 ENST00000534141.1
RAB30
RAB30, member RAS oncogene family
chr17_+_78234625 0.12 ENST00000508628.2
ENST00000582970.1
ENST00000456466.1
ENST00000319921.4
RNF213
ring finger protein 213
chr1_-_93426998 0.12 ENST00000370310.4
FAM69A
family with sequence similarity 69, member A
chr1_+_46049706 0.12 ENST00000527470.1
ENST00000525515.1
ENST00000537798.1
ENST00000402363.3
ENST00000528238.1
ENST00000350030.3
ENST00000470768.1
ENST00000372052.4
ENST00000351223.3
NASP
nuclear autoantigenic sperm protein (histone-binding)
chr6_+_168227552 0.12 ENST00000400825.4
MLLT4
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
chr17_-_46178649 0.12 ENST00000495350.1
ENST00000402583.1
CBX1
chromobox homolog 1
chr17_+_45771420 0.12 ENST00000578982.1
TBKBP1
TBK1 binding protein 1
chr13_-_49107303 0.12 ENST00000344532.3
RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr3_-_124774802 0.12 ENST00000311127.4
HEG1
heart development protein with EGF-like domains 1
chrX_-_65858865 0.12 ENST00000374719.3
ENST00000450752.1
ENST00000451436.2
EDA2R
ectodysplasin A2 receptor
chr13_+_98628886 0.12 ENST00000490680.1
ENST00000539640.1
ENST00000403772.3
IPO5
importin 5
chr12_+_53443680 0.12 ENST00000314250.6
ENST00000451358.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr4_+_79697495 0.12 ENST00000502871.1
ENST00000335016.5
BMP2K
BMP2 inducible kinase
chr7_-_154863264 0.12 ENST00000395731.2
ENST00000543018.1
HTR5A-AS1
HTR5A antisense RNA 1
chr12_+_69633407 0.12 ENST00000551516.1
CPSF6
cleavage and polyadenylation specific factor 6, 68kDa
chr20_+_13202418 0.12 ENST00000262487.4
ISM1
isthmin 1, angiogenesis inhibitor
chr9_+_131451480 0.11 ENST00000322030.8
SET
SET nuclear oncogene
chr8_+_97274119 0.11 ENST00000455950.2
PTDSS1
phosphatidylserine synthase 1
chr16_+_55357672 0.11 ENST00000290552.7
IRX6
iroquois homeobox 6
chrX_+_21958674 0.11 ENST00000404933.2
SMS
spermine synthase
chr10_-_25012597 0.11 ENST00000396432.2
ARHGAP21
Rho GTPase activating protein 21
chr4_-_41216492 0.11 ENST00000503503.1
ENST00000509446.1
ENST00000503264.1
ENST00000508707.1
ENST00000508593.1
APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr6_-_143832820 0.11 ENST00000002165.6
FUCA2
fucosidase, alpha-L- 2, plasma
chr2_+_46926326 0.11 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chrX_+_21959108 0.11 ENST00000457085.1
SMS
spermine synthase
chr16_-_30022293 0.11 ENST00000565273.1
ENST00000567332.2
ENST00000350119.4
DOC2A
double C2-like domains, alpha
chr3_-_185542761 0.11 ENST00000457616.2
ENST00000346192.3
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr8_-_74884459 0.11 ENST00000522337.1
TCEB1
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
chr10_-_133795416 0.11 ENST00000540159.1
ENST00000368636.4
BNIP3
BCL2/adenovirus E1B 19kDa interacting protein 3
chr2_-_220173685 0.11 ENST00000423636.2
ENST00000442029.1
ENST00000412847.1
PTPRN
protein tyrosine phosphatase, receptor type, N
chr5_-_73937244 0.11 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ENC1
ectodermal-neural cortex 1 (with BTB domain)
chr12_-_31744031 0.11 ENST00000389082.5
DENND5B
DENN/MADD domain containing 5B
chr5_+_139027877 0.11 ENST00000302517.3
CXXC5
CXXC finger protein 5
chr1_+_206730484 0.11 ENST00000304534.8
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr14_+_93673574 0.11 ENST00000554232.1
ENST00000556871.1
ENST00000555113.1
UBR7
ubiquitin protein ligase E3 component n-recognin 7 (putative)
chr12_-_58131931 0.11 ENST00000547588.1
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr1_+_173837488 0.11 ENST00000427304.1
ENST00000432989.1
ENST00000367702.1
ZBTB37
zinc finger and BTB domain containing 37
chr4_-_114682597 0.10 ENST00000394524.3
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chrX_+_11776278 0.10 ENST00000312196.4
ENST00000337339.2
MSL3
male-specific lethal 3 homolog (Drosophila)
chr15_+_45003675 0.10 ENST00000558401.1
ENST00000559916.1
ENST00000544417.1
B2M
beta-2-microglobulin
chr8_+_109455845 0.10 ENST00000220853.3
EMC2
ER membrane protein complex subunit 2
chr14_+_60716159 0.10 ENST00000325658.3
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr14_-_104028595 0.10 ENST00000337322.4
ENST00000445922.2
BAG5
BCL2-associated athanogene 5
chr3_-_168865522 0.10 ENST00000464456.1
MECOM
MDS1 and EVI1 complex locus
chr5_+_102594403 0.10 ENST00000319933.2
C5orf30
chromosome 5 open reading frame 30
chr1_-_228604454 0.10 ENST00000456946.2
TRIM17
tripartite motif containing 17
chr4_+_174089951 0.10 ENST00000512285.1
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr21_-_40685536 0.10 ENST00000341322.4
BRWD1
bromodomain and WD repeat domain containing 1
chr2_-_176867534 0.10 ENST00000445472.1
KIAA1715
KIAA1715
chr19_-_10047219 0.10 ENST00000264833.4
OLFM2
olfactomedin 2
chr2_-_230786378 0.10 ENST00000430954.1
TRIP12
thyroid hormone receptor interactor 12
chr6_+_43543942 0.10 ENST00000372226.1
ENST00000443535.1
POLH
polymerase (DNA directed), eta
chr18_-_74207146 0.10 ENST00000443185.2
ZNF516
zinc finger protein 516
chr2_+_33172012 0.10 ENST00000404816.2
LTBP1
latent transforming growth factor beta binding protein 1
chr2_+_242255297 0.10 ENST00000401990.1
ENST00000407971.1
ENST00000436795.1
ENST00000411484.1
ENST00000434955.1
ENST00000402092.2
ENST00000441533.1
ENST00000443492.1
ENST00000437066.1
ENST00000429791.1
SEPT2
septin 2
chr2_-_107503558 0.10 ENST00000361686.4
ENST00000409087.3
ST6GAL2
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
chr13_+_98795664 0.10 ENST00000376581.5
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr17_+_19912640 0.10 ENST00000395527.4
ENST00000583482.2
ENST00000583528.1
ENST00000583463.1
SPECC1
sperm antigen with calponin homology and coiled-coil domains 1

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF15

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.1 0.2 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.1 0.6 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.2 GO:0008052 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.1 0.3 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.1 0.2 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 0.2 GO:1905071 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.1 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.3 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.2 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.3 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.2 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0 0.2 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.3 GO:0034436 glycoprotein transport(GO:0034436)
0.0 0.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.0 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.7 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.1 GO:1903991 positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.0 0.4 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.2 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.1 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.0 0.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.3 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.1 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.1 GO:1901490 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) regulation of lymphangiogenesis(GO:1901490)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.3 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.1 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.0 0.1 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.1 GO:0061324 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.3 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.0 0.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.1 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.1 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.1 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.0 0.2 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) positive regulation of dopamine receptor signaling pathway(GO:0060161) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.1 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.0 0.1 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0003072 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.0 0.1 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.0 0.1 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626) cellular response to cobalt ion(GO:0071279) negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.1 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.4 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.2 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 0.0 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.0 0.1 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.1 GO:0090270 fibroblast growth factor production(GO:0090269) regulation of fibroblast growth factor production(GO:0090270)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.6 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.0 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.0 GO:0043634 polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.2 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.4 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.1 GO:0060032 notochord regression(GO:0060032)
0.0 0.1 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.0 1.3 GO:0090307 mitotic spindle assembly(GO:0090307)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.0 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.1 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.1 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.1 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0 0.2 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.0 GO:0050894 determination of affect(GO:0050894)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0070195 growth hormone receptor complex(GO:0070195)
0.1 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.2 GO:0031213 RSF complex(GO:0031213)
0.0 0.8 GO:0097227 sperm annulus(GO:0097227)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 1.3 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.4 GO:0001940 male pronucleus(GO:0001940)
0.0 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0051286 cell tip(GO:0051286)
0.0 0.3 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.1 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.8 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.3 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 0.2 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 0.2 GO:0016768 spermine synthase activity(GO:0016768)
0.1 0.3 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.1 0.2 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.1 0.3 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.1 0.2 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.3 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0050436 microfibril binding(GO:0050436)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.0 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0086039 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.0 0.1 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.2 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.9 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.0 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.0 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.1 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.0 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.1 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.2 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 REACTOME KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway