Project
NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for KLF12
Z-value: 1.17
Motif logo
Transcription factors associated with KLF12
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| KLF12 | hg19_v2_chr13_-_74708372_74708409 | -0.25 | 6.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr4_+_11627248 Show fit | 0.99 |
ENST00000510095.1
|
RP11-281P23.2 |
|
| chr17_-_40264321 Show fit | 0.84 |
ENST00000430773.1
ENST00000413196.2 |
DEXH (Asp-Glu-X-His) box polypeptide 58 |
|
| chr1_+_153750622 Show fit | 0.73 |
ENST00000532853.1
|
solute carrier family 27 (fatty acid transporter), member 3 |
|
| chr14_+_77425972 Show fit | 0.68 |
ENST00000553613.1
|
RP11-7F17.7 |
|
| chr1_-_47655686 Show fit | 0.65 |
ENST00000294338.2
|
PDZK1 interacting protein 1 |
|
| chr2_+_89952792 Show fit | 0.59 |
ENST00000390265.2
|
immunoglobulin kappa variable 1D-33 |
|
| chr9_+_131084846 Show fit | 0.55 |
ENST00000608951.1
|
coenzyme Q4 |
|
| chr6_+_27775899 Show fit | 0.55 |
ENST00000358739.3
|
histone cluster 1, H2ai |
|
| chr16_-_67978016 Show fit | 0.53 |
ENST00000264005.5
|
lecithin-cholesterol acyltransferase |
|
| chr2_+_90458201 Show fit | 0.53 |
ENST00000603238.1
|
Uncharacterized protein |
Network of associatons between targets according to the STRING database.
First level regulatory network of KLF12
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.1 | GO:0039534 | negative regulation of MDA-5 signaling pathway(GO:0039534) |
| 0.0 | 1.0 | GO:1901663 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.1 | 0.6 | GO:0033277 | abortive mitotic cell cycle(GO:0033277) |
| 0.1 | 0.6 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) |
| 0.0 | 0.6 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.1 | 0.5 | GO:0072287 | metanephric distal tubule morphogenesis(GO:0072287) |
| 0.1 | 0.5 | GO:0034372 | very-low-density lipoprotein particle remodeling(GO:0034372) regulation of high-density lipoprotein particle assembly(GO:0090107) |
| 0.1 | 0.5 | GO:0021555 | midbrain-hindbrain boundary morphogenesis(GO:0021555) |
| 0.0 | 0.5 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.0 | 0.5 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.1 | 0.6 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.0 | 0.6 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.1 | 0.5 | GO:0002133 | polycystin complex(GO:0002133) |
| 0.0 | 0.5 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.0 | 0.5 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.1 | 0.3 | GO:0036117 | hyaluranon cable(GO:0036117) |
| 0.0 | 0.3 | GO:1990393 | 3M complex(GO:1990393) |
| 0.1 | 0.2 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.1 | 0.2 | GO:0000333 | telomerase catalytic core complex(GO:0000333) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.7 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.1 | 0.6 | GO:0004985 | opioid receptor activity(GO:0004985) |
| 0.0 | 0.6 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 0.5 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
| 0.1 | 0.5 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
| 0.0 | 0.5 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.0 | 0.5 | GO:0001848 | complement binding(GO:0001848) |
| 0.0 | 0.4 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.0 | 0.4 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.1 | 0.3 | GO:0005055 | laminin receptor activity(GO:0005055) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | ST GA12 PATHWAY | G alpha 12 Pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.7 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.0 | 0.7 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 0.6 | REACTOME REGULATION OF IFNA SIGNALING | Genes involved in Regulation of IFNA signaling |
| 0.0 | 0.6 | REACTOME AMINE COMPOUND SLC TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.0 | 0.5 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 0.0 | 0.4 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.0 | 0.3 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.0 | 0.2 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |