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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for KLF12

Z-value: 1.17

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Transcription factors associated with KLF12

Gene Symbol Gene ID Gene Info
KLF12
ENSG00000118922.12 Kruppel like factor 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF12hg19_v2_chr13_-_74708372_74708409-0.256.3e-01Click!

Activity profile of KLF12 motif

Sorted Z-values of KLF12 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_11627248 0.99 ENST00000510095.1
RP11-281P23.2
RP11-281P23.2
chr17_-_40264321 0.84 ENST00000430773.1
ENST00000413196.2
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr1_+_153750622 0.73 ENST00000532853.1
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr14_+_77425972 0.68 ENST00000553613.1
RP11-7F17.7
RP11-7F17.7
chr1_-_47655686 0.65 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr2_+_89952792 0.59 ENST00000390265.2
IGKV1D-33
immunoglobulin kappa variable 1D-33
chr9_+_131084846 0.55 ENST00000608951.1
COQ4
coenzyme Q4
chr6_+_27775899 0.55 ENST00000358739.3
HIST1H2AI
histone cluster 1, H2ai
chr16_-_67978016 0.53 ENST00000264005.5
LCAT
lecithin-cholesterol acyltransferase
chr2_+_90458201 0.53 ENST00000603238.1
CH17-132F21.1
Uncharacterized protein
chr9_-_34637806 0.50 ENST00000477726.1
SIGMAR1
sigma non-opioid intracellular receptor 1
chr19_+_10812108 0.49 ENST00000250237.5
ENST00000592254.1
QTRT1
queuine tRNA-ribosyltransferase 1
chr11_-_64856497 0.48 ENST00000524632.1
ENST00000530719.1
AP003068.6
transmembrane protein 262
chr16_-_2168079 0.47 ENST00000488185.2
PKD1
polycystic kidney disease 1 (autosomal dominant)
chr17_-_80797886 0.42 ENST00000572562.1
ZNF750
zinc finger protein 750
chr12_-_120907374 0.40 ENST00000550458.1
SRSF9
serine/arginine-rich splicing factor 9
chr2_-_85828867 0.39 ENST00000425160.1
TMEM150A
transmembrane protein 150A
chr14_+_65170820 0.39 ENST00000555982.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr20_+_44637526 0.38 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr12_-_121973974 0.37 ENST00000538379.1
ENST00000541318.1
ENST00000541511.1
KDM2B
lysine (K)-specific demethylase 2B
chr1_+_24117627 0.33 ENST00000400061.1
LYPLA2
lysophospholipase II
chr7_+_70229899 0.33 ENST00000443672.1
AUTS2
autism susceptibility candidate 2
chr5_-_180235755 0.33 ENST00000502678.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr2_+_234104079 0.32 ENST00000417661.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr11_-_57089774 0.32 ENST00000527207.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr11_+_66360665 0.32 ENST00000310190.4
CCS
copper chaperone for superoxide dismutase
chr16_-_1843694 0.32 ENST00000569769.1
SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr11_-_102401469 0.31 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr10_+_104404644 0.31 ENST00000462202.2
TRIM8
tripartite motif containing 8
chr19_+_45312347 0.31 ENST00000270233.6
ENST00000591520.1
BCAM
basal cell adhesion molecule (Lutheran blood group)
chr7_+_66800928 0.31 ENST00000430244.1
RP11-166O4.5
RP11-166O4.5
chr17_+_1633755 0.31 ENST00000545662.1
WDR81
WD repeat domain 81
chr11_+_65154070 0.31 ENST00000317568.5
ENST00000531296.1
ENST00000533782.1
ENST00000355991.5
ENST00000416776.2
ENST00000526201.1
FRMD8
FERM domain containing 8
chr15_-_90039805 0.30 ENST00000544600.1
ENST00000268122.4
RHCG
Rh family, C glycoprotein
chr6_-_27775694 0.30 ENST00000377401.2
HIST1H2BL
histone cluster 1, H2bl
chr17_-_47841485 0.30 ENST00000506156.1
ENST00000240364.2
FAM117A
family with sequence similarity 117, member A
chr17_+_38119216 0.29 ENST00000301659.4
GSDMA
gasdermin A
chr17_-_72864739 0.29 ENST00000579893.1
ENST00000544854.1
FDXR
ferredoxin reductase
chr8_-_145086922 0.29 ENST00000530478.1
PARP10
poly (ADP-ribose) polymerase family, member 10
chr6_+_31730773 0.28 ENST00000415669.2
ENST00000425424.1
SAPCD1
suppressor APC domain containing 1
chr19_+_45174994 0.28 ENST00000403660.3
CEACAM19
carcinoembryonic antigen-related cell adhesion molecule 19
chr4_-_168155577 0.28 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr5_+_137801160 0.28 ENST00000239938.4
EGR1
early growth response 1
chr19_-_45909585 0.27 ENST00000593226.1
ENST00000418234.2
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr10_-_77161533 0.27 ENST00000535216.1
ZNF503
zinc finger protein 503
chr12_-_54778444 0.27 ENST00000551771.1
ZNF385A
zinc finger protein 385A
chr5_-_139422654 0.26 ENST00000289409.4
ENST00000358522.3
ENST00000378238.4
ENST00000289422.7
ENST00000361474.1
ENST00000545385.1
ENST00000394770.1
ENST00000541337.1
NRG2
neuregulin 2
chr10_-_71906342 0.26 ENST00000287078.6
ENST00000335494.5
TYSND1
trypsin domain containing 1
chr11_-_62474803 0.26 ENST00000533982.1
ENST00000360796.5
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr7_+_143013198 0.26 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr6_+_31895467 0.26 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr2_+_220309379 0.25 ENST00000451076.1
SPEG
SPEG complex locus
chr17_-_40264692 0.25 ENST00000591220.1
ENST00000251642.3
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr16_+_69140122 0.25 ENST00000219322.3
HAS3
hyaluronan synthase 3
chr19_+_40871734 0.25 ENST00000359274.5
PLD3
phospholipase D family, member 3
chr4_-_74904398 0.24 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr16_+_30671223 0.24 ENST00000568722.1
FBRS
fibrosin
chr2_-_220435963 0.24 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
OBSL1
obscurin-like 1
chr3_+_38032216 0.24 ENST00000416303.1
VILL
villin-like
chr5_-_121413974 0.24 ENST00000231004.4
LOX
lysyl oxidase
chr6_+_31895480 0.23 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2
CFB
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr1_+_239882842 0.23 ENST00000448020.1
CHRM3
cholinergic receptor, muscarinic 3
chr19_-_44097188 0.23 ENST00000594374.1
L34079.2
L34079.2
chr14_+_102276192 0.23 ENST00000557714.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr19_+_19303720 0.22 ENST00000392324.4
RFXANK
regulatory factor X-associated ankyrin-containing protein
chr17_+_1665253 0.22 ENST00000254722.4
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr2_+_12858355 0.22 ENST00000405331.3
TRIB2
tribbles pseudokinase 2
chr17_-_4889508 0.22 ENST00000574606.2
CAMTA2
calmodulin binding transcription activator 2
chr11_+_61159832 0.22 ENST00000334888.5
ENST00000398979.3
TMEM216
transmembrane protein 216
chr3_+_46449049 0.22 ENST00000357392.4
ENST00000400880.3
ENST00000433848.1
CCRL2
chemokine (C-C motif) receptor-like 2
chr19_-_56109119 0.21 ENST00000587678.1
FIZ1
FLT3-interacting zinc finger 1
chr19_+_49109990 0.21 ENST00000321762.1
SPACA4
sperm acrosome associated 4
chr15_+_40531243 0.21 ENST00000558055.1
ENST00000455577.2
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr1_-_203274418 0.21 ENST00000457348.1
RP11-134P9.1
long intergenic non-protein coding RNA 1136
chr19_+_41094612 0.21 ENST00000595726.1
SHKBP1
SH3KBP1 binding protein 1
chr17_-_40828969 0.21 ENST00000591022.1
ENST00000587627.1
ENST00000293349.6
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr17_-_2117600 0.21 ENST00000572369.1
SMG6
SMG6 nonsense mediated mRNA decay factor
chr1_-_119543994 0.21 ENST00000439394.1
ENST00000449439.1
RP4-712E4.1
RP4-712E4.2
RP4-712E4.1
RP4-712E4.2
chr12_+_7060508 0.20 ENST00000541698.1
ENST00000542462.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr11_-_62995986 0.20 ENST00000403374.2
SLC22A25
solute carrier family 22, member 25
chr19_-_46000251 0.20 ENST00000590526.1
ENST00000344680.4
ENST00000245923.4
RTN2
reticulon 2
chr20_+_34287364 0.20 ENST00000374072.1
ENST00000397416.1
ENST00000336695.4
ROMO1
reactive oxygen species modulator 1
chr1_-_114355083 0.20 ENST00000261441.5
RSBN1
round spermatid basic protein 1
chr16_-_31519691 0.20 ENST00000567994.1
ENST00000430477.2
ENST00000570164.1
ENST00000327237.2
C16orf58
chromosome 16 open reading frame 58
chr14_-_85996332 0.19 ENST00000380722.1
RP11-497E19.1
RP11-497E19.1
chr19_+_7600584 0.19 ENST00000600737.1
PNPLA6
patatin-like phospholipase domain containing 6
chr8_+_145691411 0.19 ENST00000301332.2
KIFC2
kinesin family member C2
chr16_+_103816 0.19 ENST00000383018.3
ENST00000417493.1
SNRNP25
small nuclear ribonucleoprotein 25kDa (U11/U12)
chr11_-_57089671 0.19 ENST00000532437.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr12_+_7060414 0.19 ENST00000538715.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr1_+_109792641 0.19 ENST00000271332.3
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2
chr11_-_65374430 0.18 ENST00000532507.1
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr3_-_61237050 0.18 ENST00000476844.1
ENST00000488467.1
ENST00000492590.1
ENST00000468189.1
FHIT
fragile histidine triad
chr2_+_220495800 0.18 ENST00000413743.1
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr19_-_46272106 0.18 ENST00000560168.1
SIX5
SIX homeobox 5
chr19_+_39214797 0.18 ENST00000440400.1
ACTN4
actinin, alpha 4
chr1_+_28918712 0.18 ENST00000373826.3
RAB42
RAB42, member RAS oncogene family
chr10_-_52645416 0.18 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
A1CF
APOBEC1 complementation factor
chr3_+_52454971 0.18 ENST00000465863.1
PHF7
PHD finger protein 7
chr6_+_35773070 0.18 ENST00000373853.1
ENST00000360215.1
LHFPL5
lipoma HMGIC fusion partner-like 5
chr16_-_790982 0.17 ENST00000301694.5
ENST00000251588.2
NARFL
nuclear prelamin A recognition factor-like
chr20_-_36794902 0.17 ENST00000373403.3
TGM2
transglutaminase 2
chr15_-_64673630 0.17 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
KIAA0101
chr4_-_168155169 0.17 ENST00000534949.1
ENST00000535728.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr11_+_45918092 0.17 ENST00000395629.2
MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr6_-_31864977 0.17 ENST00000395728.3
ENST00000375528.4
EHMT2
euchromatic histone-lysine N-methyltransferase 2
chr14_+_52313833 0.17 ENST00000553560.1
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr7_+_2687173 0.17 ENST00000403167.1
TTYH3
tweety family member 3
chr11_+_117070037 0.17 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
TAGLN
transgelin
chr9_+_131085095 0.17 ENST00000372875.3
COQ4
coenzyme Q4
chr22_-_31536480 0.17 ENST00000215885.3
PLA2G3
phospholipase A2, group III
chr16_+_85646763 0.16 ENST00000411612.1
ENST00000253458.7
GSE1
Gse1 coiled-coil protein
chr9_+_131084815 0.16 ENST00000300452.3
ENST00000609948.1
COQ4
coenzyme Q4
chr3_+_193853927 0.16 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr10_-_77161650 0.16 ENST00000372524.4
ZNF503
zinc finger protein 503
chr19_-_51412584 0.16 ENST00000431178.2
KLK4
kallikrein-related peptidase 4
chr4_-_11430221 0.16 ENST00000514690.1
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr2_+_172864490 0.16 ENST00000315796.4
METAP1D
methionyl aminopeptidase type 1D (mitochondrial)
chr11_-_61129335 0.16 ENST00000545361.1
ENST00000539128.1
ENST00000546151.1
ENST00000447532.2
CYB561A3
cytochrome b561 family, member A3
chr1_-_76398077 0.16 ENST00000284142.6
ASB17
ankyrin repeat and SOCS box containing 17
chr7_-_135433534 0.16 ENST00000338588.3
FAM180A
family with sequence similarity 180, member A
chr1_-_151254362 0.16 ENST00000447795.2
RP11-126K1.2
Uncharacterized protein
chr10_-_51371321 0.15 ENST00000602930.1
AGAP8
ArfGAP with GTPase domain, ankyrin repeat and PH domain 8
chr20_+_34287194 0.15 ENST00000374078.1
ENST00000374077.3
ROMO1
reactive oxygen species modulator 1
chr19_-_47164386 0.15 ENST00000391916.2
ENST00000410105.2
DACT3
dishevelled-binding antagonist of beta-catenin 3
chr1_+_162336686 0.15 ENST00000420220.1
C1orf226
chromosome 1 open reading frame 226
chr14_-_74417096 0.15 ENST00000286544.3
FAM161B
family with sequence similarity 161, member B
chr5_+_145718587 0.15 ENST00000230732.4
POU4F3
POU class 4 homeobox 3
chr12_-_117319236 0.15 ENST00000257572.5
HRK
harakiri, BCL2 interacting protein (contains only BH3 domain)
chrX_+_68048803 0.15 ENST00000204961.4
EFNB1
ephrin-B1
chr1_+_1243947 0.15 ENST00000379031.5
PUSL1
pseudouridylate synthase-like 1
chr19_+_19303572 0.15 ENST00000407360.3
ENST00000540981.1
RFXANK
regulatory factor X-associated ankyrin-containing protein
chr22_-_24110063 0.15 ENST00000520222.1
ENST00000401675.3
CHCHD10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr16_+_58010339 0.15 ENST00000290871.5
ENST00000441824.2
TEPP
testis, prostate and placenta expressed
chr15_-_34394119 0.15 ENST00000256545.4
EMC7
ER membrane protein complex subunit 7
chr19_+_46000479 0.15 ENST00000456399.2
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr15_+_40531621 0.14 ENST00000560346.1
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr5_+_139493665 0.14 ENST00000331327.3
PURA
purine-rich element binding protein A
chr19_+_5914213 0.14 ENST00000222125.5
ENST00000452990.2
ENST00000588865.1
CAPS
calcyphosine
chr5_+_159343688 0.14 ENST00000306675.3
ADRA1B
adrenoceptor alpha 1B
chr17_-_39637392 0.14 ENST00000246639.2
ENST00000393989.1
KRT35
keratin 35
chr17_+_2240775 0.14 ENST00000268989.3
ENST00000426855.2
SGSM2
small G protein signaling modulator 2
chrX_-_48325857 0.14 ENST00000376875.1
SLC38A5
solute carrier family 38, member 5
chr17_+_7487146 0.14 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
MPDU1
mannose-P-dolichol utilization defect 1
chr15_+_74218787 0.14 ENST00000261921.7
LOXL1
lysyl oxidase-like 1
chr17_-_79827808 0.14 ENST00000580685.1
ARHGDIA
Rho GDP dissociation inhibitor (GDI) alpha
chr21_-_38445297 0.14 ENST00000430792.1
ENST00000399103.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr12_+_7060432 0.14 ENST00000318974.9
ENST00000456013.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr11_+_20620946 0.14 ENST00000525748.1
SLC6A5
solute carrier family 6 (neurotransmitter transporter), member 5
chr19_+_14063278 0.14 ENST00000254337.6
DCAF15
DDB1 and CUL4 associated factor 15
chr17_-_41174367 0.14 ENST00000587173.1
VAT1
vesicle amine transport 1
chr16_+_28875126 0.14 ENST00000359285.5
ENST00000538342.1
SH2B1
SH2B adaptor protein 1
chr1_+_61330931 0.14 ENST00000371191.1
NFIA
nuclear factor I/A
chr17_+_27071002 0.14 ENST00000262395.5
ENST00000422344.1
ENST00000444415.3
ENST00000262396.6
TRAF4
TNF receptor-associated factor 4
chr10_-_103880209 0.13 ENST00000425280.1
LDB1
LIM domain binding 1
chr17_+_8191815 0.13 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RANGRF
RAN guanine nucleotide release factor
chr17_+_7308172 0.13 ENST00000575301.1
NLGN2
neuroligin 2
chr16_+_30194916 0.13 ENST00000570045.1
ENST00000565497.1
ENST00000570244.1
CORO1A
coronin, actin binding protein, 1A
chr3_-_53381539 0.13 ENST00000606822.1
ENST00000294241.6
ENST00000607628.1
DCP1A
decapping mRNA 1A
chr10_-_32636106 0.13 ENST00000263062.8
ENST00000319778.6
EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr19_+_4474846 0.13 ENST00000589486.1
ENST00000592691.1
HDGFRP2
Hepatoma-derived growth factor-related protein 2
chr9_-_134151915 0.13 ENST00000372271.3
FAM78A
family with sequence similarity 78, member A
chr5_-_1882858 0.13 ENST00000511126.1
ENST00000231357.2
IRX4
iroquois homeobox 4
chr1_-_155177677 0.13 ENST00000368378.3
ENST00000541990.1
ENST00000457183.2
THBS3
thrombospondin 3
chr19_+_50381308 0.12 ENST00000599049.2
TBC1D17
TBC1 domain family, member 17
chr17_+_17584763 0.12 ENST00000353383.1
RAI1
retinoic acid induced 1
chr16_-_30798492 0.12 ENST00000262525.4
ZNF629
zinc finger protein 629
chr16_+_811073 0.12 ENST00000382862.3
ENST00000563651.1
MSLN
mesothelin
chr11_-_118966167 0.12 ENST00000530167.1
H2AFX
H2A histone family, member X
chr19_+_41092680 0.12 ENST00000594298.1
ENST00000597396.1
SHKBP1
SH3KBP1 binding protein 1
chr17_+_57784826 0.12 ENST00000262291.4
VMP1
vacuole membrane protein 1
chr9_+_139886846 0.12 ENST00000371620.3
C9orf142
chromosome 9 open reading frame 142
chr9_-_99064429 0.12 ENST00000375263.3
HSD17B3
hydroxysteroid (17-beta) dehydrogenase 3
chr1_+_16693578 0.12 ENST00000401088.4
ENST00000471507.1
ENST00000401089.3
ENST00000375590.3
ENST00000492354.1
SZRD1
SUZ RNA binding domain containing 1
chr22_-_31742218 0.12 ENST00000266269.5
ENST00000405309.3
ENST00000351933.4
PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr14_-_24020858 0.12 ENST00000419474.3
ZFHX2
zinc finger homeobox 2
chr14_+_65171315 0.11 ENST00000394691.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr19_+_45174724 0.11 ENST00000358777.4
CEACAM19
carcinoembryonic antigen-related cell adhesion molecule 19
chr14_+_96343100 0.11 ENST00000503525.2
LINC00617
long intergenic non-protein coding RNA 617
chr14_-_74416829 0.11 ENST00000534936.1
FAM161B
family with sequence similarity 161, member B
chr3_+_52350335 0.11 ENST00000420323.2
DNAH1
dynein, axonemal, heavy chain 1
chr3_-_51994694 0.11 ENST00000395014.2
PCBP4
poly(rC) binding protein 4
chr10_+_104404218 0.11 ENST00000302424.7
TRIM8
tripartite motif containing 8
chr17_-_36906058 0.11 ENST00000580830.1
PCGF2
polycomb group ring finger 2
chr16_-_19897455 0.11 ENST00000568214.1
ENST00000569479.1
GPRC5B
G protein-coupled receptor, family C, group 5, member B
chr19_+_50380917 0.11 ENST00000535102.2
TBC1D17
TBC1 domain family, member 17
chr17_-_40829026 0.11 ENST00000412503.1
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr11_-_67120974 0.11 ENST00000539074.1
ENST00000312419.3
POLD4
polymerase (DNA-directed), delta 4, accessory subunit
chr16_-_2264779 0.11 ENST00000333503.7
PGP
phosphoglycolate phosphatase
chr3_-_119379427 0.11 ENST00000264231.3
ENST00000468801.1
ENST00000538678.1
POPDC2
popeye domain containing 2
chr1_-_159832438 0.11 ENST00000368100.1
VSIG8
V-set and immunoglobulin domain containing 8
chr2_-_97509749 0.10 ENST00000331001.2
ENST00000318357.4
ANKRD23
ankyrin repeat domain 23
chr5_-_2751762 0.10 ENST00000302057.5
ENST00000382611.6
IRX2
iroquois homeobox 2
chrX_-_74743080 0.10 ENST00000373367.3
ZDHHC15
zinc finger, DHHC-type containing 15
chr6_-_134639180 0.10 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr2_-_208634287 0.10 ENST00000295417.3
FZD5
frizzled family receptor 5
chr2_+_173724771 0.10 ENST00000538974.1
ENST00000540783.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr2_+_36923933 0.10 ENST00000497382.1
ENST00000404084.1
ENST00000379241.3
ENST00000401530.1
VIT
vitrin
chr16_+_28875268 0.10 ENST00000395532.4
SH2B1
SH2B adaptor protein 1
chr2_-_74710078 0.10 ENST00000290418.4
CCDC142
coiled-coil domain containing 142

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 0.5 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.1 0.3 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.3 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.5 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1 0.3 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 0.6 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.3 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.3 GO:0050720 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720)
0.1 0.3 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.2 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.1 0.2 GO:0015747 urate transport(GO:0015747)
0.1 0.5 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1 0.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.6 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 0.2 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 0.3 GO:0010847 regulation of chromatin assembly(GO:0010847) protein auto-ADP-ribosylation(GO:0070213)
0.1 0.2 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.1 0.3 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.4 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.4 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 0.1 GO:1902568 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) regulation of eosinophil activation(GO:1902566) positive regulation of eosinophil activation(GO:1902568)
0.0 1.0 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0035623 renal glucose absorption(GO:0035623)
0.0 0.3 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.1 GO:0018277 protein deamination(GO:0018277)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.4 GO:0051715 cytolysis in other organism(GO:0051715)
0.0 0.2 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.2 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.1 GO:0032796 uropod organization(GO:0032796)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.6 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.0 0.4 GO:0015816 glycine transport(GO:0015816)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0006562 proline catabolic process(GO:0006562) proline catabolic process to glutamate(GO:0010133)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) positive regulation of gastric acid secretion(GO:0060454) response to capsazepine(GO:1901594)
0.0 0.1 GO:0051891 pancreatic A cell differentiation(GO:0003310) positive regulation of cardioblast differentiation(GO:0051891)
0.0 0.1 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.0 0.1 GO:0002118 aggressive behavior(GO:0002118)
0.0 0.1 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.1 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0 0.4 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.1 GO:1904252 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) negative regulation of bile acid biosynthetic process(GO:0070858) acinar cell differentiation(GO:0090425) negative regulation of bile acid metabolic process(GO:1904252) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.2 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.0 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.0 0.1 GO:1901805 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.2 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.2 GO:0044849 estrous cycle(GO:0044849)
0.0 0.5 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.1 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.0 0.3 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.2 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.0 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.0 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.3 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.3 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0036117 hyaluranon cable(GO:0036117)
0.1 0.5 GO:0002133 polycystin complex(GO:0002133)
0.1 0.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.2 GO:0032279 asymmetric synapse(GO:0032279)
0.1 0.2 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.3 GO:1990393 3M complex(GO:1990393)
0.0 0.2 GO:0097361 CIA complex(GO:0097361)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.0 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.0 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.0 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.8 GO:0045171 intercellular bridge(GO:0045171)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005055 laminin receptor activity(GO:0005055)
0.1 0.5 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.3 GO:0016730 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.1 0.5 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 0.3 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.1 0.6 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.3 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.1 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.0 0.1 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.0 GO:0001002 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.0 0.5 GO:0001848 complement binding(GO:0001848)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.0 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 ST GA12 PATHWAY G alpha 12 Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.6 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.6 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac