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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ISX

Z-value: 0.67

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Transcription factors associated with ISX

Gene Symbol Gene ID Gene Info
ISX
ENSG00000175329.8 intestine specific homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ISXhg19_v2_chr22_+_35462129_35462156-0.187.4e-01Click!

Activity profile of ISX motif

Sorted Z-values of ISX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_153044083 0.70 ENST00000341611.2
SPRR2B
small proline-rich protein 2B
chr7_+_37723336 0.65 ENST00000450180.1
GPR141
G protein-coupled receptor 141
chr16_-_55866997 0.59 ENST00000360526.3
ENST00000361503.4
CES1
carboxylesterase 1
chr17_-_18266818 0.43 ENST00000583780.1
SHMT1
serine hydroxymethyltransferase 1 (soluble)
chr8_-_82395461 0.42 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chr6_+_3259148 0.34 ENST00000419065.2
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr22_+_46476192 0.32 ENST00000443490.1
FLJ27365
hsa-mir-4763
chr16_-_55867146 0.28 ENST00000422046.2
CES1
carboxylesterase 1
chr11_+_77532233 0.25 ENST00000525409.1
AAMDC
adipogenesis associated, Mth938 domain containing
chr18_-_67624412 0.22 ENST00000580335.1
CD226
CD226 molecule
chr7_+_142985467 0.22 ENST00000392925.2
CASP2
caspase 2, apoptosis-related cysteine peptidase
chr4_-_171012844 0.22 ENST00000502392.1
AADAT
aminoadipate aminotransferase
chr2_+_90248739 0.21 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chr7_-_112635675 0.19 ENST00000447785.1
ENST00000451962.1
AC018464.3
AC018464.3
chr5_-_147286065 0.19 ENST00000318315.4
ENST00000515291.1
C5orf46
chromosome 5 open reading frame 46
chr15_-_75199213 0.18 ENST00000562698.1
FAM219B
family with sequence similarity 219, member B
chr7_-_92107229 0.18 ENST00000603053.1
ERVW-1
endogenous retrovirus group W, member 1
chr16_+_31724618 0.18 ENST00000530881.1
ENST00000529515.1
ZNF720
zinc finger protein 720
chr20_-_35580104 0.17 ENST00000373694.5
SAMHD1
SAM domain and HD domain 1
chr4_+_147145709 0.17 ENST00000504313.1
RP11-6L6.2
Uncharacterized protein
chr1_+_155278625 0.17 ENST00000368356.4
ENST00000356657.6
FDPS
farnesyl diphosphate synthase
chr14_-_24711470 0.16 ENST00000559969.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr14_-_24711806 0.16 ENST00000540705.1
ENST00000538777.1
ENST00000558566.1
ENST00000559019.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr6_+_30687978 0.16 ENST00000327892.8
ENST00000435534.1
TUBB
tubulin, beta class I
chr4_-_19458597 0.16 ENST00000505347.1
RP11-3J1.1
RP11-3J1.1
chr5_+_53686658 0.16 ENST00000512618.1
LINC01033
long intergenic non-protein coding RNA 1033
chr14_-_24711865 0.15 ENST00000399423.4
ENST00000267415.7
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr1_+_32666188 0.15 ENST00000421922.2
CCDC28B
coiled-coil domain containing 28B
chr9_+_34646651 0.15 ENST00000378842.3
GALT
galactose-1-phosphate uridylyltransferase
chr4_-_48018680 0.15 ENST00000513178.1
CNGA1
cyclic nucleotide gated channel alpha 1
chr17_+_46970127 0.14 ENST00000355938.5
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr17_+_46970134 0.14 ENST00000503641.1
ENST00000514808.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr1_+_155278539 0.13 ENST00000447866.1
FDPS
farnesyl diphosphate synthase
chr5_+_150226085 0.13 ENST00000522154.1
IRGM
immunity-related GTPase family, M
chr10_-_104001231 0.13 ENST00000370002.3
PITX3
paired-like homeodomain 3
chr14_-_24711764 0.13 ENST00000557921.1
ENST00000558476.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr5_-_177580855 0.13 ENST00000514354.1
ENST00000511078.1
NHP2
NHP2 ribonucleoprotein
chr1_-_36916011 0.13 ENST00000356637.5
ENST00000354267.3
ENST00000235532.5
OSCP1
organic solute carrier partner 1
chr6_-_31125850 0.13 ENST00000507751.1
ENST00000448162.2
ENST00000502557.1
ENST00000503420.1
ENST00000507892.1
ENST00000507226.1
ENST00000513222.1
ENST00000503934.1
ENST00000396263.2
ENST00000508683.1
ENST00000428174.1
ENST00000448141.2
ENST00000507829.1
ENST00000455279.2
ENST00000376266.5
CCHCR1
coiled-coil alpha-helical rod protein 1
chr19_-_52307357 0.12 ENST00000594900.1
FPR1
formyl peptide receptor 1
chr6_-_85474219 0.12 ENST00000369663.5
TBX18
T-box 18
chr6_+_160542870 0.12 ENST00000324965.4
ENST00000457470.2
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr2_-_228244013 0.12 ENST00000304568.3
TM4SF20
transmembrane 4 L six family member 20
chr5_+_177631497 0.11 ENST00000358344.3
HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr20_-_17662705 0.11 ENST00000455029.2
RRBP1
ribosome binding protein 1
chr9_+_34646624 0.11 ENST00000450095.2
ENST00000556278.1
GALT
GALT
galactose-1-phosphate uridylyltransferase
Uncharacterized protein
chr1_+_28261533 0.11 ENST00000411604.1
ENST00000373888.4
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr1_-_21620877 0.11 ENST00000527991.1
ECE1
endothelin converting enzyme 1
chrX_-_153363125 0.11 ENST00000407218.1
ENST00000453960.2
MECP2
methyl CpG binding protein 2 (Rett syndrome)
chr17_-_77005813 0.11 ENST00000590370.1
ENST00000591625.1
CANT1
calcium activated nucleotidase 1
chr6_-_39693111 0.11 ENST00000373215.3
ENST00000538893.1
ENST00000287152.7
ENST00000373216.3
KIF6
kinesin family member 6
chr14_-_88200641 0.10 ENST00000556168.1
RP11-1152H15.1
RP11-1152H15.1
chr2_-_96700664 0.10 ENST00000359548.4
ENST00000377137.3
ENST00000439254.1
ENST00000453542.1
GPAT2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr19_-_10227503 0.10 ENST00000593054.1
EIF3G
eukaryotic translation initiation factor 3, subunit G
chr17_+_42785976 0.10 ENST00000393547.2
ENST00000398338.3
DBF4B
DBF4 homolog B (S. cerevisiae)
chr7_+_148982396 0.10 ENST00000418158.2
ZNF783
zinc finger family member 783
chr10_-_1095050 0.10 ENST00000381344.3
IDI1
isopentenyl-diphosphate delta isomerase 1
chr5_+_177631523 0.10 ENST00000506339.1
ENST00000355836.5
ENST00000514633.1
ENST00000515193.1
ENST00000506259.1
ENST00000504898.1
HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr17_+_40440481 0.10 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
STAT5A
signal transducer and activator of transcription 5A
chr2_+_204571375 0.10 ENST00000374478.4
CD28
CD28 molecule
chr5_-_177580933 0.10 ENST00000274606.3
NHP2
NHP2 ribonucleoprotein
chr19_-_3557570 0.10 ENST00000355415.2
MFSD12
major facilitator superfamily domain containing 12
chr2_-_198540719 0.10 ENST00000295049.4
RFTN2
raftlin family member 2
chr20_-_50419055 0.10 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr14_-_73925225 0.10 ENST00000356296.4
ENST00000355058.3
ENST00000359560.3
ENST00000557597.1
ENST00000554394.1
ENST00000555238.1
ENST00000535282.1
ENST00000555987.1
ENST00000555394.1
ENST00000554546.1
NUMB
numb homolog (Drosophila)
chr17_-_42277203 0.10 ENST00000587097.1
ATXN7L3
ataxin 7-like 3
chr10_-_99205607 0.09 ENST00000477692.2
ENST00000485122.2
ENST00000370886.5
ENST00000370885.4
ENST00000370902.3
ENST00000370884.5
EXOSC1
exosome component 1
chr12_-_51422017 0.09 ENST00000394904.3
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr6_+_160542821 0.09 ENST00000366963.4
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr3_+_111393501 0.09 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr17_-_12920994 0.09 ENST00000609101.1
ELAC2
elaC ribonuclease Z 2
chr12_+_3000073 0.09 ENST00000397132.2
TULP3
tubby like protein 3
chr6_+_34204642 0.08 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr4_-_89442940 0.08 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr17_-_40337470 0.08 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr11_+_63953587 0.08 ENST00000305218.4
ENST00000538945.1
STIP1
stress-induced-phosphoprotein 1
chr16_+_3070313 0.08 ENST00000326577.4
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr4_-_138453606 0.08 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr6_+_31126291 0.08 ENST00000376257.3
ENST00000376255.4
TCF19
transcription factor 19
chr16_+_89160217 0.08 ENST00000317447.4
ENST00000537290.1
ACSF3
acyl-CoA synthetase family member 3
chr9_-_4666421 0.08 ENST00000381895.5
SPATA6L
spermatogenesis associated 6-like
chr1_+_28261492 0.08 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr11_-_26744908 0.08 ENST00000533617.1
SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr5_+_140557371 0.07 ENST00000239444.2
PCDHB8
protocadherin beta 8
chr7_-_2883928 0.07 ENST00000275364.3
GNA12
guanine nucleotide binding protein (G protein) alpha 12
chr12_+_7014126 0.07 ENST00000415834.1
ENST00000436789.1
LRRC23
leucine rich repeat containing 23
chr6_+_53948328 0.07 ENST00000370876.2
MLIP
muscular LMNA-interacting protein
chr5_-_177580777 0.07 ENST00000314397.4
NHP2
NHP2 ribonucleoprotein
chr1_-_43833628 0.07 ENST00000413844.2
ENST00000372458.3
ELOVL1
ELOVL fatty acid elongase 1
chr14_-_104181771 0.07 ENST00000554913.1
ENST00000554974.1
ENST00000553361.1
ENST00000555055.1
ENST00000555964.1
ENST00000556682.1
ENST00000445556.1
ENST00000553332.1
ENST00000352127.7
XRCC3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr2_-_227050079 0.07 ENST00000423838.1
AC068138.1
AC068138.1
chr14_-_81425828 0.07 ENST00000555529.1
ENST00000556042.1
ENST00000556981.1
CEP128
centrosomal protein 128kDa
chr17_+_59489112 0.06 ENST00000335108.2
C17orf82
chromosome 17 open reading frame 82
chr8_+_22132810 0.06 ENST00000356766.6
PIWIL2
piwi-like RNA-mediated gene silencing 2
chr4_-_141348763 0.06 ENST00000509477.1
CLGN
calmegin
chr5_-_137374288 0.06 ENST00000514310.1
FAM13B
family with sequence similarity 13, member B
chr17_+_46970178 0.06 ENST00000393366.2
ENST00000506855.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr12_+_7013897 0.06 ENST00000007969.8
ENST00000323702.5
LRRC23
leucine rich repeat containing 23
chrX_+_19362011 0.06 ENST00000379806.5
ENST00000545074.1
ENST00000540249.1
ENST00000423505.1
ENST00000417819.1
ENST00000422285.2
ENST00000355808.5
ENST00000379805.3
PDHA1
pyruvate dehydrogenase (lipoamide) alpha 1
chr12_-_57039739 0.06 ENST00000552959.1
ENST00000551020.1
ENST00000553007.2
ENST00000552919.1
ENST00000552104.1
ENST00000262030.3
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr16_-_31106048 0.06 ENST00000300851.6
VKORC1
vitamin K epoxide reductase complex, subunit 1
chr17_+_73452695 0.06 ENST00000582186.1
ENST00000582455.1
ENST00000581252.1
ENST00000579208.1
KIAA0195
KIAA0195
chr19_+_42811093 0.06 ENST00000595750.1
PRR19
proline rich 19
chr20_+_55967129 0.06 ENST00000371219.2
RBM38
RNA binding motif protein 38
chrX_-_24690771 0.06 ENST00000379145.1
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr6_-_33385655 0.05 ENST00000440279.3
ENST00000607266.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr5_+_53751445 0.05 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr17_-_77005801 0.05 ENST00000392446.5
CANT1
calcium activated nucleotidase 1
chr12_-_10978957 0.05 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr6_-_33385902 0.05 ENST00000374500.5
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr16_+_3070356 0.05 ENST00000341627.5
ENST00000575124.1
ENST00000575836.1
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr16_+_3333443 0.05 ENST00000572748.1
ENST00000573578.1
ENST00000574253.1
ZNF263
zinc finger protein 263
chr17_+_36508826 0.05 ENST00000580660.1
SOCS7
suppressor of cytokine signaling 7
chr17_-_79650689 0.05 ENST00000574938.1
ENST00000570561.1
ENST00000573392.1
ENST00000576135.1
ARL16
ADP-ribosylation factor-like 16
chr3_+_186288454 0.05 ENST00000265028.3
DNAJB11
DnaJ (Hsp40) homolog, subfamily B, member 11
chr15_+_64680003 0.05 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr17_-_12920907 0.05 ENST00000609757.1
ENST00000581499.2
ENST00000580504.1
ELAC2
elaC ribonuclease Z 2
chr17_-_38821373 0.05 ENST00000394052.3
KRT222
keratin 222
chr1_-_150849174 0.05 ENST00000515192.1
ARNT
aryl hydrocarbon receptor nuclear translocator
chr6_-_33385854 0.05 ENST00000488478.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr1_-_150849047 0.05 ENST00000354396.2
ENST00000505755.1
ARNT
aryl hydrocarbon receptor nuclear translocator
chr8_+_38831683 0.04 ENST00000302495.4
HTRA4
HtrA serine peptidase 4
chr4_+_110736659 0.04 ENST00000394631.3
ENST00000226796.6
GAR1
GAR1 ribonucleoprotein
chrX_-_153363188 0.04 ENST00000303391.6
MECP2
methyl CpG binding protein 2 (Rett syndrome)
chr1_+_222910625 0.04 ENST00000360827.2
FAM177B
family with sequence similarity 177, member B
chr12_+_26348246 0.04 ENST00000422622.2
SSPN
sarcospan
chr16_-_31106211 0.04 ENST00000532364.1
ENST00000529564.1
ENST00000319788.7
ENST00000354895.4
ENST00000394975.2
RP11-196G11.1
VKORC1
Uncharacterized protein
vitamin K epoxide reductase complex, subunit 1
chr7_-_2883650 0.04 ENST00000544127.1
GNA12
guanine nucleotide binding protein (G protein) alpha 12
chr17_+_78965624 0.04 ENST00000325167.5
CHMP6
charged multivesicular body protein 6
chrX_+_43515467 0.04 ENST00000338702.3
ENST00000542639.1
MAOA
monoamine oxidase A
chr14_-_20801427 0.04 ENST00000557665.1
ENST00000358932.4
ENST00000353689.4
CCNB1IP1
cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
chrX_+_77154935 0.04 ENST00000481445.1
COX7B
cytochrome c oxidase subunit VIIb
chrX_+_8432871 0.04 ENST00000381032.1
ENST00000453306.1
ENST00000444481.1
VCX3B
variable charge, X-linked 3B
chr8_+_22132847 0.04 ENST00000521356.1
PIWIL2
piwi-like RNA-mediated gene silencing 2
chr7_+_144052381 0.04 ENST00000498580.1
ENST00000056217.5
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr17_-_79650818 0.04 ENST00000397498.4
ARL16
ADP-ribosylation factor-like 16
chr1_+_151735431 0.04 ENST00000321531.5
ENST00000315067.8
OAZ3
ornithine decarboxylase antizyme 3
chr16_+_1359511 0.04 ENST00000397514.3
ENST00000397515.2
ENST00000567383.1
ENST00000403747.2
ENST00000566587.1
UBE2I
ubiquitin-conjugating enzyme E2I
chr18_-_67624160 0.04 ENST00000581982.1
ENST00000280200.4
CD226
CD226 molecule
chr1_-_209824643 0.04 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr19_-_36001113 0.04 ENST00000434389.1
DMKN
dermokine
chr17_+_78518617 0.04 ENST00000537330.1
ENST00000570891.1
RPTOR
regulatory associated protein of MTOR, complex 1
chr17_+_45286387 0.03 ENST00000572316.1
ENST00000354968.1
ENST00000576874.1
ENST00000536623.2
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr12_+_70574088 0.03 ENST00000552324.1
RP11-320P7.2
RP11-320P7.2
chr22_+_29138013 0.03 ENST00000216027.3
ENST00000398941.2
HSCB
HscB mitochondrial iron-sulfur cluster co-chaperone
chr1_-_205819245 0.03 ENST00000367136.4
PM20D1
peptidase M20 domain containing 1
chr22_-_24303340 0.03 ENST00000404172.3
ENST00000290765.4
GSTT2B
glutathione S-transferase theta 2B (gene/pseudogene)
chr17_+_79650962 0.03 ENST00000329138.4
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr11_+_119205222 0.03 ENST00000311413.4
RNF26
ring finger protein 26
chr6_+_36562132 0.03 ENST00000373715.6
ENST00000339436.7
SRSF3
serine/arginine-rich splicing factor 3
chr6_-_33385870 0.03 ENST00000488034.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr22_+_24322322 0.03 ENST00000215780.5
ENST00000402588.3
GSTT2
glutathione S-transferase theta 2
chr6_+_73076432 0.03 ENST00000414192.2
RIMS1
regulating synaptic membrane exocytosis 1
chrX_-_6453159 0.03 ENST00000381089.3
ENST00000398729.1
VCX3A
variable charge, X-linked 3A
chr19_-_46285736 0.03 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
DMPK
dystrophia myotonica-protein kinase
chr17_+_79651007 0.03 ENST00000572392.1
ENST00000577012.1
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr1_+_28261621 0.03 ENST00000549094.1
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr21_+_35014783 0.03 ENST00000381291.4
ENST00000381285.4
ENST00000399367.3
ENST00000399352.1
ENST00000399355.2
ENST00000399349.1
ITSN1
intersectin 1 (SH3 domain protein)
chr19_+_12902289 0.03 ENST00000302754.4
JUNB
jun B proto-oncogene
chr3_+_28390637 0.03 ENST00000420223.1
ENST00000383768.2
ZCWPW2
zinc finger, CW type with PWWP domain 2
chr14_-_73924954 0.03 ENST00000555307.1
ENST00000554818.1
NUMB
numb homolog (Drosophila)
chr4_+_155702496 0.03 ENST00000510397.1
RBM46
RNA binding motif protein 46
chr12_+_7014064 0.03 ENST00000443597.2
LRRC23
leucine rich repeat containing 23
chr1_-_75100539 0.03 ENST00000420661.2
C1orf173
chromosome 1 open reading frame 173
chr17_-_18266660 0.03 ENST00000582653.1
ENST00000352886.6
SHMT1
serine hydroxymethyltransferase 1 (soluble)
chr18_-_67623906 0.03 ENST00000583955.1
CD226
CD226 molecule
chr10_+_124914285 0.03 ENST00000407911.2
BUB3
BUB3 mitotic checkpoint protein
chrX_+_8433376 0.03 ENST00000440654.2
ENST00000381029.4
VCX3B
variable charge, X-linked 3B
chrY_+_14813160 0.03 ENST00000338981.3
USP9Y
ubiquitin specific peptidase 9, Y-linked
chr9_+_71357171 0.03 ENST00000440050.1
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr9_+_125315391 0.03 ENST00000373688.2
OR1N2
olfactory receptor, family 1, subfamily N, member 2
chr12_-_22063787 0.02 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr1_-_150849208 0.02 ENST00000358595.5
ARNT
aryl hydrocarbon receptor nuclear translocator
chr4_-_177190364 0.02 ENST00000296525.3
ASB5
ankyrin repeat and SOCS box containing 5
chr17_-_27418537 0.02 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr11_-_62414070 0.02 ENST00000540933.1
ENST00000346178.4
ENST00000356638.3
ENST00000534779.1
ENST00000525994.1
GANAB
glucosidase, alpha; neutral AB
chr2_-_183387283 0.02 ENST00000435564.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr1_-_36915880 0.02 ENST00000445843.3
OSCP1
organic solute carrier partner 1
chr9_+_1050331 0.02 ENST00000382255.3
ENST00000382251.3
ENST00000412350.2
DMRT2
doublesex and mab-3 related transcription factor 2
chr13_-_88323514 0.02 ENST00000441617.1
MIR4500HG
MIR4500 host gene (non-protein coding)
chr16_+_89160269 0.02 ENST00000540697.1
ENST00000406948.3
ENST00000378345.4
ENST00000541755.2
ACSF3
acyl-CoA synthetase family member 3
chr7_-_36764004 0.02 ENST00000431169.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr10_+_124913930 0.02 ENST00000368858.5
BUB3
BUB3 mitotic checkpoint protein
chr1_+_44115814 0.02 ENST00000372396.3
KDM4A
lysine (K)-specific demethylase 4A
chr17_-_7307358 0.02 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
TMEM256
TMEM256-PLSCR3
transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chr21_+_35014706 0.02 ENST00000399353.1
ENST00000444491.1
ENST00000381318.3
ITSN1
intersectin 1 (SH3 domain protein)
chr22_-_50523760 0.02 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr17_+_42786051 0.02 ENST00000315005.3
DBF4B
DBF4 homolog B (S. cerevisiae)
chr17_-_74733404 0.02 ENST00000508921.3
ENST00000583836.1
ENST00000358156.6
ENST00000392485.2
ENST00000359995.5
SRSF2
serine/arginine-rich splicing factor 2
chr6_-_30080863 0.02 ENST00000540829.1
TRIM31
tripartite motif containing 31
chr11_-_108093329 0.02 ENST00000278612.8
NPAT
nuclear protein, ataxia-telangiectasia locus
chr12_+_3000037 0.02 ENST00000544943.1
ENST00000448120.2
TULP3
tubby like protein 3
chr5_-_95297678 0.02 ENST00000237853.4
ELL2
elongation factor, RNA polymerase II, 2
chr6_+_29795595 0.02 ENST00000360323.6
ENST00000376818.3
ENST00000376815.3
HLA-G
major histocompatibility complex, class I, G
chr3_-_186288097 0.02 ENST00000446782.1
TBCCD1
TBCC domain containing 1
chr4_-_174255400 0.02 ENST00000506267.1
HMGB2
high mobility group box 2
chr4_+_108911036 0.02 ENST00000505878.1
HADH
hydroxyacyl-CoA dehydrogenase
chr2_+_124782857 0.02 ENST00000431078.1
CNTNAP5
contactin associated protein-like 5
chr3_+_113775576 0.02 ENST00000485050.1
ENST00000281273.4
QTRTD1
queuine tRNA-ribosyltransferase domain containing 1
chr5_-_159846399 0.02 ENST00000297151.4
SLU7
SLU7 splicing factor homolog (S. cerevisiae)

Network of associatons between targets according to the STRING database.

First level regulatory network of ISX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.1 0.3 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.1 0.3 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.1 0.6 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.1 0.3 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.1 0.2 GO:0009405 pathogenesis(GO:0009405)
0.0 0.3 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.1 GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.0 0.2 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.1 GO:0060829 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.0 0.2 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512) L-kynurenine metabolic process(GO:0097052)
0.0 0.2 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.3 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.1 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.2 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0060434 bronchus morphogenesis(GO:0060434)
0.0 0.1 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.4 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.0 0.1 GO:0090410 malonate catabolic process(GO:0090410)
0.0 0.1 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0 0.1 GO:0050992 dimethylallyl diphosphate biosynthetic process(GO:0050992) dimethylallyl diphosphate metabolic process(GO:0050993)
0.0 0.0 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.1 GO:0015692 lead ion transport(GO:0015692)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.0 0.3 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0036338 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.1 GO:1990298 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1 0.2 GO:0047536 2-aminoadipate transaminase activity(GO:0047536)
0.1 0.2 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.1 0.3 GO:0070905 serine binding(GO:0070905)
0.1 0.3 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.1 GO:0090409 malonyl-CoA synthetase activity(GO:0090409)
0.0 0.1 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.0 0.2 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.3 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.0 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism