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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for IRX5

Z-value: 1.23

Motif logo

Transcription factors associated with IRX5

Gene Symbol Gene ID Gene Info
ENSG00000176842.10 iroquois homeobox 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRX5hg19_v2_chr16_+_54964740_54964789-0.148.0e-01Click!

Activity profile of IRX5 motif

Sorted Z-values of IRX5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_141264597 2.83 ENST00000338517.4
ENST00000394203.3
ENST00000506322.1
short coiled-coil protein
chr14_+_73563735 1.54 ENST00000532192.1
RNA binding motif protein 25
chr6_+_71104588 1.32 ENST00000418403.1
RP11-462G2.1
chr15_+_66585555 0.98 ENST00000319194.5
ENST00000525134.2
ENST00000441424.2
DIS3 mitotic control homolog (S. cerevisiae)-like
chr1_-_186365908 0.96 ENST00000598663.1
Uncharacterized protein
chr13_+_97928395 0.96 ENST00000445661.2
muscleblind-like splicing regulator 2
chr16_+_48657361 0.89 ENST00000565072.1
RP11-42I10.1
chr1_+_158969752 0.82 ENST00000566111.1
interferon, gamma-inducible protein 16
chr14_+_39944025 0.74 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
chr10_-_115904361 0.69 ENST00000428953.1
ENST00000543782.1
chromosome 10 open reading frame 118
chr11_+_31531291 0.64 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
elongator acetyltransferase complex subunit 4
chr17_+_58018269 0.64 ENST00000591035.1
Uncharacterized protein
chr1_-_197115818 0.57 ENST00000367409.4
ENST00000294732.7
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr5_+_136070614 0.57 ENST00000502421.1
CTB-1I21.1
chr1_+_63989004 0.56 ENST00000371088.4
EF-hand calcium binding domain 7
chr12_-_100486668 0.54 ENST00000550544.1
ENST00000551980.1
ENST00000548045.1
ENST00000545232.2
ENST00000551973.1
UHRF1 binding protein 1-like
chr4_-_104119528 0.54 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
centromere protein E, 312kDa
chr7_+_116451100 0.50 ENST00000464223.1
ENST00000484325.1
capping protein (actin filament) muscle Z-line, alpha 2
chr1_-_115124257 0.49 ENST00000369541.3
breast carcinoma amplified sequence 2
chr7_+_116502527 0.49 ENST00000361183.3
capping protein (actin filament) muscle Z-line, alpha 2
chr4_+_71091786 0.49 ENST00000317987.5
follicular dendritic cell secreted protein
chr14_+_56127989 0.48 ENST00000555573.1
kinectin 1 (kinesin receptor)
chr8_-_17555164 0.46 ENST00000297488.6
microtubule associated tumor suppressor 1
chr1_+_53480598 0.46 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
sterol carrier protein 2
chr10_-_18944123 0.46 ENST00000606425.1
Uncharacterized protein
chr13_-_38172863 0.46 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
periostin, osteoblast specific factor
chr8_+_101349823 0.44 ENST00000519566.1
KB-1991G8.1
chr4_-_75695366 0.43 ENST00000512743.1
betacellulin
chr1_+_212475148 0.42 ENST00000537030.3
protein phosphatase 2, regulatory subunit B', alpha
chr12_+_32655048 0.42 ENST00000427716.2
ENST00000266482.3
FYVE, RhoGEF and PH domain containing 4
chr1_-_116383738 0.42 ENST00000320238.3
nescient helix loop helix 2
chr12_-_76462713 0.41 ENST00000552056.1
nucleosome assembly protein 1-like 1
chr3_+_180586536 0.41 ENST00000465551.1
fragile X mental retardation, autosomal homolog 1
chr10_-_96829246 0.41 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
cytochrome P450, family 2, subfamily C, polypeptide 8
chr16_+_76668895 0.40 ENST00000512279.1
RP11-96P7.1
chr4_+_159131630 0.38 ENST00000504569.1
ENST00000509278.1
ENST00000514558.1
ENST00000503200.1
transmembrane protein 144
chr5_+_128300810 0.36 ENST00000262462.4
solute carrier family 27 (fatty acid transporter), member 6
chr14_+_56127960 0.36 ENST00000553624.1
kinectin 1 (kinesin receptor)
chr13_-_34250861 0.35 ENST00000445227.1
ENST00000454681.2
RP11-141M1.3
chr1_+_87012753 0.35 ENST00000370563.3
chloride channel accessory 4
chr7_+_77469439 0.34 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
putative homeodomain transcription factor 2
chr4_-_104119488 0.34 ENST00000514974.1
centromere protein E, 312kDa
chr3_-_27498235 0.34 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr2_+_160590469 0.34 ENST00000409591.1
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
chr11_+_114310237 0.33 ENST00000539119.1
RNA exonuclease 2
chr12_-_58329819 0.33 ENST00000551421.1
RP11-620J15.3
chr11_-_104905840 0.32 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr1_-_244006528 0.32 ENST00000336199.5
ENST00000263826.5
v-akt murine thymoma viral oncogene homolog 3
chr10_+_118349920 0.31 ENST00000531984.1
pancreatic lipase-related protein 1
chr6_-_111804905 0.31 ENST00000358835.3
ENST00000435970.1
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr4_+_144312659 0.31 ENST00000509992.1
GRB2-associated binding protein 1
chr6_-_111804393 0.31 ENST00000368802.3
ENST00000368805.1
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr5_-_93447333 0.30 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
family with sequence similarity 172, member A
chr16_+_19535133 0.30 ENST00000396212.2
ENST00000381396.5
centriolar coiled coil protein 110kDa
chr15_+_65204075 0.29 ENST00000380230.3
ENST00000357698.3
ENST00000395720.1
ENST00000496660.1
ENST00000319580.8
ankyrin repeat and death domain containing 1A
chr2_-_206950996 0.29 ENST00000414320.1
INO80 complex subunit D
chr17_-_29641104 0.29 ENST00000577894.1
ENST00000330927.4
ecotropic viral integration site 2B
chrX_+_12809463 0.29 ENST00000380663.3
ENST00000380668.5
ENST00000398491.2
ENST00000489404.1
phosphoribosyl pyrophosphate synthetase 2
chr5_+_81601166 0.29 ENST00000439350.1
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr12_+_32655110 0.29 ENST00000546442.1
ENST00000583694.1
FYVE, RhoGEF and PH domain containing 4
chr10_-_35379524 0.29 ENST00000374751.3
ENST00000374742.1
ENST00000602371.1
cullin 2
chr18_-_28622774 0.28 ENST00000434452.1
desmocollin 3
chr11_-_35547572 0.28 ENST00000378880.2
peptidase domain containing associated with muscle regeneration 1
chr12_-_10282742 0.28 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
C-type lectin domain family 7, member A
chr2_+_38177575 0.28 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
regulator of microtubule dynamics 2
chr3_-_196987309 0.27 ENST00000453607.1
discs, large homolog 1 (Drosophila)
chr10_+_90484301 0.27 ENST00000404190.1
lipase, family member K
chr12_+_2912363 0.27 ENST00000544366.1
FK506 binding protein 4, 59kDa
chr16_+_19535235 0.27 ENST00000565376.2
ENST00000396208.2
centriolar coiled coil protein 110kDa
chr15_+_41057818 0.27 ENST00000558467.1
GTP cyclohydrolase I feedback regulator
chr12_-_123728548 0.26 ENST00000545406.1
M-phase phosphoprotein 9
chr15_+_66585879 0.26 ENST00000319212.4
DIS3 mitotic control homolog (S. cerevisiae)-like
chrX_-_138790348 0.26 ENST00000414978.1
ENST00000519895.1
MCF.2 cell line derived transforming sequence
chr1_+_196788887 0.26 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
complement factor H-related 1
complement factor H-related 2
chrX_-_83757399 0.26 ENST00000373177.2
ENST00000297977.5
ENST00000506585.2
ENST00000449553.2
highly divergent homeobox
chr15_+_81225699 0.25 ENST00000560027.1
KIAA1199
chr2_-_88125471 0.25 ENST00000398146.3
RANBP2-like and GRIP domain containing 2
chr18_-_32924372 0.25 ENST00000261332.6
ENST00000399061.3
zinc finger protein 24
chr6_+_26217159 0.25 ENST00000303910.2
histone cluster 1, H2ae
chr7_+_13141010 0.24 ENST00000443947.1
AC011288.2
chr12_-_52867569 0.24 ENST00000252250.6
keratin 6C
chr3_-_9994021 0.24 ENST00000411976.2
ENST00000412055.1
proline-rich transmembrane protein 3
chr20_+_54933971 0.24 ENST00000371384.3
ENST00000437418.1
family with sequence similarity 210, member B
chr4_+_130017268 0.23 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
chromosome 4 open reading frame 33
chr18_+_22006580 0.23 ENST00000284202.4
impact RWD domain protein
chr3_-_168865522 0.23 ENST00000464456.1
MDS1 and EVI1 complex locus
chr1_+_87012922 0.23 ENST00000263723.5
chloride channel accessory 4
chr14_-_23623577 0.23 ENST00000422941.2
ENST00000453702.1
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr11_-_6790286 0.22 ENST00000338569.2
olfactory receptor, family 2, subfamily AG, member 2
chr17_-_29641084 0.22 ENST00000544462.1
ecotropic viral integration site 2B
chr4_+_76995855 0.22 ENST00000355810.4
ENST00000349321.3
ADP-ribosyltransferase 3
chr9_-_19065082 0.22 ENST00000415524.1
HAUS augmin-like complex, subunit 6
chr3_+_111630451 0.22 ENST00000495180.1
pleckstrin homology-like domain, family B, member 2
chr10_+_118187379 0.22 ENST00000369230.3
pancreatic lipase-related protein 3
chr12_-_11036844 0.22 ENST00000428168.2
proline-rich protein HaeIII subfamily 1
chr12_-_25102252 0.21 ENST00000261192.7
branched chain amino-acid transaminase 1, cytosolic
chr22_+_20877924 0.21 ENST00000445189.1
mediator complex subunit 15
chr1_-_62190793 0.21 ENST00000371177.2
ENST00000606498.1
TM2 domain containing 1
chr15_-_56757329 0.21 ENST00000260453.3
meiosis-specific nuclear structural 1
chr3_+_160473996 0.20 ENST00000498165.1
protein phosphatase, Mg2+/Mn2+ dependent, 1L
chr6_+_116850174 0.20 ENST00000416171.2
ENST00000368597.2
ENST00000452373.1
ENST00000405399.1
family with sequence similarity 26, member D
chr7_-_55583740 0.19 ENST00000453256.1
vesicular, overexpressed in cancer, prosurvival protein 1
chr6_+_149887377 0.19 ENST00000367419.5
glycoprotein integral membrane 1
chr12_+_5541267 0.18 ENST00000423158.3
neurotrophin 3
chr10_-_91403625 0.17 ENST00000322191.6
ENST00000342512.3
ENST00000371774.2
pantothenate kinase 1
chr9_-_125667618 0.17 ENST00000423239.2
ring finger and CCCH-type domains 2
chr2_+_191792376 0.17 ENST00000409428.1
ENST00000409215.1
glutaminase
chr17_+_18380051 0.17 ENST00000581545.1
ENST00000582333.1
ENST00000328114.6
ENST00000412421.2
ENST00000583322.1
ENST00000584941.1
lectin, galactoside-binding, soluble, 9C
chr1_-_114355083 0.17 ENST00000261441.5
round spermatid basic protein 1
chr8_-_101724989 0.17 ENST00000517403.1
poly(A) binding protein, cytoplasmic 1
chr9_-_3489428 0.17 ENST00000451859.1
regulatory factor X, 3 (influences HLA class II expression)
chr5_+_179135246 0.16 ENST00000508787.1
calnexin
chr12_+_75874460 0.16 ENST00000266659.3
GLI pathogenesis-related 1
chr1_+_220267429 0.16 ENST00000366922.1
ENST00000302637.5
isoleucyl-tRNA synthetase 2, mitochondrial
chr1_+_87458692 0.16 ENST00000370548.2
ENST00000356813.4
Heparan sulfate 2-O-sulfotransferase 1
heparan sulfate 2-O-sulfotransferase 1
chr15_+_92006567 0.16 ENST00000554333.1
RP11-661P17.1
chr6_+_106988986 0.16 ENST00000457437.1
ENST00000535438.1
absent in melanoma 1
chr13_+_50589390 0.16 ENST00000360473.4
ENST00000312942.1
potassium channel regulator
chr19_-_44388116 0.15 ENST00000587539.1
zinc finger protein 404
chr15_-_64665911 0.15 ENST00000606793.1
ENST00000561349.1
ENST00000560278.1
Uncharacterized protein
chr1_+_202317815 0.15 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
protein phosphatase 1, regulatory subunit 12B
chr18_+_6729725 0.15 ENST00000400091.2
ENST00000583410.1
ENST00000584387.1
Rho GTPase activating protein 28
chr2_-_32490801 0.14 ENST00000360906.5
ENST00000342905.6
NLR family, CARD domain containing 4
chr9_+_95909309 0.14 ENST00000366188.2
RP11-370F5.4
chr3_+_186383741 0.14 ENST00000232003.4
histidine-rich glycoprotein
chr5_+_54455946 0.14 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
glutathione peroxidase 8 (putative)
chr6_+_53948221 0.14 ENST00000460844.2
muscular LMNA-interacting protein
chr3_-_20053741 0.14 ENST00000389050.4
protein phosphatase 2C-like domain containing 1
chr5_+_169011033 0.14 ENST00000513795.1
spindle apparatus coiled-coil protein 1
chr19_-_52531600 0.14 ENST00000356322.6
ENST00000270649.6
zinc finger protein 614
chr18_-_44702668 0.14 ENST00000256433.3
immediate early response 3 interacting protein 1
chr2_+_173686303 0.13 ENST00000397087.3
Rap guanine nucleotide exchange factor (GEF) 4
chr19_-_44952635 0.13 ENST00000592308.1
ENST00000588931.1
ENST00000291187.4
zinc finger protein 229
chr8_+_120885949 0.13 ENST00000523492.1
ENST00000286234.5
DEP domain containing MTOR-interacting protein
chr8_-_116504448 0.13 ENST00000518018.1
trichorhinophalangeal syndrome I
chr3_-_3221358 0.13 ENST00000424814.1
ENST00000450014.1
ENST00000231948.4
ENST00000432408.2
cereblon
chr6_+_12008986 0.13 ENST00000491710.1
human immunodeficiency virus type I enhancer binding protein 1
chr18_-_69246167 0.13 ENST00000566582.1
RP11-510D19.1
chr6_-_138833630 0.13 ENST00000533765.1
NHS-like 1
chr21_+_38792602 0.13 ENST00000398960.2
ENST00000398956.2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr10_+_90660832 0.13 ENST00000371924.1
STAM binding protein-like 1
chr13_-_46716969 0.13 ENST00000435666.2
lymphocyte cytosolic protein 1 (L-plastin)
chr8_-_101962777 0.12 ENST00000395951.3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr7_-_99573677 0.12 ENST00000292401.4
alpha-2-glycoprotein 1, zinc-binding
chr19_-_2740036 0.12 ENST00000586572.1
ENST00000269740.4
Uncharacterized protein
solute carrier family 39 (zinc transporter), member 3
chr12_-_120315074 0.12 ENST00000261833.7
ENST00000392521.2
citron (rho-interacting, serine/threonine kinase 21)
chr19_-_52227221 0.12 ENST00000222115.1
ENST00000540069.2
hyaluronan synthase 1
chr4_+_41361616 0.12 ENST00000513024.1
LIM and calponin homology domains 1
chr14_-_95624227 0.12 ENST00000526495.1
dicer 1, ribonuclease type III
chr1_-_160492994 0.11 ENST00000368055.1
ENST00000368057.3
ENST00000368059.3
SLAM family member 6
chr4_+_17616253 0.11 ENST00000237380.7
mediator complex subunit 28
chr7_-_99573640 0.11 ENST00000411734.1
alpha-2-glycoprotein 1, zinc-binding
chr1_-_85156417 0.11 ENST00000422026.1
synovial sarcoma, X breakpoint 2 interacting protein
chr16_+_1578674 0.10 ENST00000253934.5
transmembrane protein 204
chr5_+_169010638 0.10 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
spindle apparatus coiled-coil protein 1
chr4_-_186392898 0.10 ENST00000510617.1
ENST00000307588.3
coiled-coil domain containing 110
chr4_+_26344754 0.09 ENST00000515573.1
recombination signal binding protein for immunoglobulin kappa J region
chr3_-_81792780 0.09 ENST00000489715.1
glucan (1,4-alpha-), branching enzyme 1
chr11_+_114310102 0.09 ENST00000265881.5
RNA exonuclease 2
chr5_+_67576109 0.09 ENST00000522084.1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr1_-_8763278 0.09 ENST00000468247.1
arginine-glutamic acid dipeptide (RE) repeats
chr13_+_24844857 0.09 ENST00000409126.1
ENST00000343003.6
spermatogenesis associated 13
chr14_-_23624511 0.09 ENST00000529705.2
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr13_+_96085847 0.09 ENST00000376873.3
claudin 10
chrX_-_19988382 0.09 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
chromosome X open reading frame 23
chr7_-_111424506 0.08 ENST00000450156.1
ENST00000494651.2
dedicator of cytokinesis 4
chr11_-_22647350 0.08 ENST00000327470.3
Fanconi anemia, complementation group F
chrX_-_15353629 0.08 ENST00000333590.4
ENST00000428964.1
ENST00000542278.1
phosphatidylinositol glycan anchor biosynthesis, class A
chr2_-_32490859 0.08 ENST00000404025.2
NLR family, CARD domain containing 4
chr18_-_69246186 0.08 ENST00000568095.1
RP11-510D19.1
chr12_+_58335360 0.08 ENST00000300145.3
XRCC6 binding protein 1
chr8_+_67976593 0.08 ENST00000262210.5
ENST00000412460.1
centrosome and spindle pole associated protein 1
chr4_+_113558612 0.08 ENST00000505034.1
ENST00000324052.6
La ribonucleoprotein domain family, member 7
chr7_+_133615169 0.08 ENST00000541309.1
exocyst complex component 4
chr14_+_51706886 0.08 ENST00000457354.2
thioredoxin-related transmembrane protein 1
chr1_+_97188188 0.07 ENST00000541987.1
polypyrimidine tract binding protein 2
chr19_-_40596828 0.07 ENST00000414720.2
ENST00000455521.1
ENST00000340963.5
ENST00000595773.1
zinc finger protein 780A
chr3_+_46283944 0.07 ENST00000452454.1
ENST00000457243.1
chemokine (C-C motif) receptor 3
chr17_-_6524159 0.07 ENST00000589033.1
KIAA0753
chr4_+_80584903 0.07 ENST00000506460.1
RP11-452C8.1
chr15_+_49170083 0.07 ENST00000530028.2
EP300 interacting inhibitor of differentiation 1
chr8_+_9009202 0.07 ENST00000518496.1
Uncharacterized protein
chr7_-_112430427 0.07 ENST00000449743.1
ENST00000441474.1
ENST00000454074.1
ENST00000447395.1
transmembrane protein 168
chr4_-_103998439 0.06 ENST00000503230.1
ENST00000503818.1
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr14_+_50291993 0.06 ENST00000595378.1
HCG1786899; PRO2610; Uncharacterized protein
chrX_+_108779004 0.05 ENST00000218004.1
nuclear transport factor 2-like export factor 2
chr8_+_27631903 0.05 ENST00000305188.8
establishment of sister chromatid cohesion N-acetyltransferase 2
chr12_+_56114189 0.05 ENST00000548082.1
retinol dehydrogenase 5 (11-cis/9-cis)
chr19_-_12992274 0.05 ENST00000592506.1
ENST00000222219.3
deoxyribonuclease II, lysosomal
chr2_+_201173667 0.05 ENST00000409755.3
spermatogenesis associated, serine-rich 2-like
chr16_-_58585513 0.05 ENST00000245138.4
ENST00000567285.1
CCR4-NOT transcription complex, subunit 1
chr8_-_67976509 0.05 ENST00000518747.1
COP9 signalosome subunit 5
chr17_-_67264947 0.05 ENST00000586811.1
ATP-binding cassette, sub-family A (ABC1), member 5
chr4_+_189376725 0.05 ENST00000510832.1
ENST00000510005.1
ENST00000503458.1
long intergenic non-protein coding RNA 1060
chr18_+_33709834 0.04 ENST00000358232.6
ENST00000351393.6
ENST00000442325.2
ENST00000423854.2
ENST00000350494.6
ENST00000542824.1
elongator acetyltransferase complex subunit 2
chr19_+_20959098 0.04 ENST00000360204.5
ENST00000594534.1
zinc finger protein 66
chr8_-_108510224 0.04 ENST00000517746.1
ENST00000297450.3
angiopoietin 1
chr1_-_227505289 0.04 ENST00000366765.3
CDC42 binding protein kinase alpha (DMPK-like)
chr12_+_106751436 0.04 ENST00000228347.4
polymerase (RNA) III (DNA directed) polypeptide B
chr17_-_47723943 0.04 ENST00000510476.1
ENST00000503676.1
speckle-type POZ protein

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.2 2.8 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.6 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.9 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.5 GO:0032571 response to vitamin K(GO:0032571)
0.1 0.3 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.1 0.3 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.2 GO:0071262 regulation of eIF2 alpha phosphorylation by amino acid starvation(GO:0060733) regulation of translational initiation in response to starvation(GO:0071262) positive regulation of translational initiation in response to starvation(GO:0071264)
0.1 0.5 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.4 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.1 0.3 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 0.4 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 0.2 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.1 1.3 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.2 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.2 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 2.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.3 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.3 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.2 GO:0070269 pyroptosis(GO:0070269)
0.0 0.2 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 1.0 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.4 GO:0035810 positive regulation of urine volume(GO:0035810)
0.0 0.6 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.3 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.4 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.3 GO:0002643 regulation of tolerance induction(GO:0002643)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.2 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:1905068 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.4 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.9 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.2 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.3 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 1.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.7 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.6 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.1 1.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.6 GO:0072687 meiotic spindle(GO:0072687)
0.1 1.0 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.3 GO:0030891 VCB complex(GO:0030891)
0.0 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0043219 lateral loop(GO:0043219)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0070538 oleic acid binding(GO:0070538)
0.1 1.1 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.3 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.1 0.3 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.3 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1 0.6 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.2 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.2 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.4 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.3 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 1.7 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.6 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.4 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.8 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0008320 protein transmembrane transporter activity(GO:0008320)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling