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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for IRF2_STAT2_IRF8_IRF1

Z-value: 5.02

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Transcription factors associated with IRF2_STAT2_IRF8_IRF1

Gene Symbol Gene ID Gene Info
ENSG00000168310.6 IRF2
ENSG00000170581.9 STAT2
ENSG00000140968.6 IRF8
ENSG00000125347.9 IRF1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT2hg19_v2_chr12_-_56753858_567539300.945.4e-03Click!
IRF1hg19_v2_chr5_-_131826457_1318265140.592.1e-01Click!
IRF2hg19_v2_chr4_-_185395672_1853957340.167.6e-01Click!

Activity profile of IRF2_STAT2_IRF8_IRF1 motif

Sorted Z-values of IRF2_STAT2_IRF8_IRF1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF2_STAT2_IRF8_IRF1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_79086088 27.05 ENST00000370751.5
ENST00000342282.3
IFI44L
interferon-induced protein 44-like
chr14_+_94577074 26.54 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
IFI27
interferon, alpha-inducible protein 27
chr21_+_42733870 15.45 ENST00000330714.3
ENST00000436410.1
ENST00000435611.1
MX2
myxovirus (influenza virus) resistance 2 (mouse)
chr21_+_42792442 12.87 ENST00000398600.2
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr1_-_27998689 11.50 ENST00000339145.4
ENST00000362020.4
ENST00000361157.6
IFI6
interferon, alpha-inducible protein 6
chr12_+_113416191 10.51 ENST00000342315.4
ENST00000392583.2
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr17_+_6659354 9.89 ENST00000574907.1
XAF1
XIAP associated factor 1
chr13_-_43566301 9.82 ENST00000398762.3
ENST00000313640.7
ENST00000313624.7
EPSTI1
epithelial stromal interaction 1 (breast)
chr6_+_32821924 9.73 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr12_+_113376157 9.28 ENST00000228928.7
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr11_-_615942 9.07 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
IRF7
interferon regulatory factor 7
chr10_+_91152303 8.57 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr12_+_113416340 8.32 ENST00000552756.1
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr12_+_113376249 7.74 ENST00000551007.1
ENST00000548514.1
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr19_-_17516449 7.49 ENST00000252593.6
BST2
bone marrow stromal cell antigen 2
chr1_+_948803 7.47 ENST00000379389.4
ISG15
ISG15 ubiquitin-like modifier
chr10_+_91087651 7.18 ENST00000371818.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr10_+_91092241 6.30 ENST00000371811.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr15_-_80263506 5.87 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr21_+_42798094 5.80 ENST00000398598.3
ENST00000455164.2
ENST00000424365.1
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr17_+_6659153 5.76 ENST00000441631.1
ENST00000438512.1
ENST00000346752.4
ENST00000361842.3
XAF1
XIAP associated factor 1
chr12_+_113344811 5.24 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr11_-_615570 5.13 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chr1_+_79115503 4.67 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr4_-_76944621 4.39 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr12_+_113344582 3.82 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr21_+_42798124 3.81 ENST00000417963.1
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr1_-_114429997 3.44 ENST00000471267.1
ENST00000393320.3
BCL2L15
BCL2-like 15
chr12_+_113416265 3.41 ENST00000449768.2
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr17_-_40264692 3.33 ENST00000591220.1
ENST00000251642.3
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr21_+_42797958 3.27 ENST00000419044.1
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr21_+_42798158 3.24 ENST00000441677.1
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr14_+_24630465 3.21 ENST00000557894.1
ENST00000559284.1
ENST00000560275.1
IRF9
interferon regulatory factor 9
chr3_-_122283100 3.19 ENST00000492382.1
ENST00000462315.1
PARP9
poly (ADP-ribose) polymerase family, member 9
chr17_-_4643114 3.18 ENST00000293778.6
CXCL16
chemokine (C-X-C motif) ligand 16
chr8_-_23540402 3.12 ENST00000523261.1
ENST00000380871.4
NKX3-1
NK3 homeobox 1
chr17_-_40264321 3.08 ENST00000430773.1
ENST00000413196.2
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr3_-_122283079 3.03 ENST00000471785.1
ENST00000466126.1
PARP9
poly (ADP-ribose) polymerase family, member 9
chr9_+_5510558 2.91 ENST00000397747.3
PDCD1LG2
programmed cell death 1 ligand 2
chr17_+_25958174 2.90 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
LGALS9
lectin, galactoside-binding, soluble, 9
chr2_-_163175133 2.86 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chr6_+_116782527 2.81 ENST00000368606.3
ENST00000368605.1
FAM26F
family with sequence similarity 26, member F
chr4_-_122148620 2.78 ENST00000509841.1
TNIP3
TNFAIP3 interacting protein 3
chr2_-_191878874 2.76 ENST00000392322.3
ENST00000392323.2
ENST00000424722.1
ENST00000361099.3
STAT1
signal transducer and activator of transcription 1, 91kDa
chr3_-_122283424 2.76 ENST00000477522.2
ENST00000360356.2
PARP9
poly (ADP-ribose) polymerase family, member 9
chr6_+_126240442 2.72 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7
nuclear receptor coactivator 7
chr17_-_4643161 2.72 ENST00000574412.1
CXCL16
chemokine (C-X-C motif) ligand 16
chr2_-_191878681 2.68 ENST00000409465.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr7_-_92777606 2.45 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr5_-_95158375 2.43 ENST00000512469.2
ENST00000379979.4
ENST00000505427.1
ENST00000508780.1
GLRX
glutaredoxin (thioltransferase)
chr15_+_89182178 2.34 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr9_-_32526299 2.24 ENST00000379882.1
ENST00000379883.2
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr11_+_313503 2.17 ENST00000528780.1
ENST00000328221.5
IFITM1
interferon induced transmembrane protein 1
chr3_+_187086120 2.17 ENST00000259030.2
RTP4
receptor (chemosensory) transporter protein 4
chr2_-_7005785 2.12 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr9_-_32526184 2.11 ENST00000545044.1
ENST00000379868.1
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr8_-_79717750 2.08 ENST00000263851.4
ENST00000379113.2
IL7
interleukin 7
chr11_-_321050 2.07 ENST00000399808.4
IFITM3
interferon induced transmembrane protein 3
chr17_+_41994576 2.02 ENST00000588043.2
FAM215A
family with sequence similarity 215, member A (non-protein coding)
chr6_+_32811885 2.00 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAPSAR1
PSMB9
TAP1 and PSMB8 antisense RNA 1
proteasome (prosome, macropain) subunit, beta type, 9
chr11_-_60719213 1.93 ENST00000227880.3
SLC15A3
solute carrier family 15 (oligopeptide transporter), member 3
chr11_-_18258342 1.91 ENST00000278222.4
SAA4
serum amyloid A4, constitutive
chr17_+_6658878 1.90 ENST00000574394.1
XAF1
XIAP associated factor 1
chr17_-_43339474 1.89 ENST00000331780.4
SPATA32
spermatogenesis associated 32
chr12_-_49318715 1.88 ENST00000444214.2
FKBP11
FK506 binding protein 11, 19 kDa
chr9_+_5510492 1.88 ENST00000397745.2
PDCD1LG2
programmed cell death 1 ligand 2
chr6_-_32821599 1.88 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr7_+_74188309 1.85 ENST00000289473.4
ENST00000433458.1
NCF1
neutrophil cytosolic factor 1
chr6_+_27775899 1.83 ENST00000358739.3
HIST1H2AI
histone cluster 1, H2ai
chr16_+_12059091 1.82 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr11_-_57334732 1.81 ENST00000526659.1
ENST00000527022.1
UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr15_+_89182156 1.79 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr6_+_3259148 1.74 ENST00000419065.2
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr15_+_74287035 1.71 ENST00000395132.2
ENST00000268059.6
ENST00000354026.6
ENST00000268058.3
ENST00000565898.1
ENST00000569477.1
ENST00000569965.1
ENST00000567543.1
ENST00000436891.3
ENST00000435786.2
ENST00000564428.1
ENST00000359928.4
PML
promyelocytic leukemia
chr11_-_102826434 1.63 ENST00000340273.4
ENST00000260302.3
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr1_+_59486059 1.62 ENST00000447329.1
RP4-794H19.4
RP4-794H19.4
chr8_-_145060593 1.61 ENST00000313059.5
ENST00000524918.1
ENST00000313028.7
ENST00000525773.1
PARP10
poly (ADP-ribose) polymerase family, member 10
chr3_-_146262637 1.60 ENST00000472349.1
ENST00000342435.4
PLSCR1
phospholipid scramblase 1
chr3_-_146262352 1.58 ENST00000462666.1
PLSCR1
phospholipid scramblase 1
chr6_-_32811771 1.58 ENST00000395339.3
ENST00000374882.3
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8
chr12_+_102271129 1.56 ENST00000258534.8
DRAM1
DNA-damage regulated autophagy modulator 1
chr12_-_49319265 1.55 ENST00000552878.1
ENST00000453172.2
FKBP11
FK506 binding protein 11, 19 kDa
chr22_-_36635225 1.54 ENST00000529194.1
APOL2
apolipoprotein L, 2
chr19_+_17516494 1.54 ENST00000534306.1
CTD-2521M24.9
CTD-2521M24.9
chr1_+_110453608 1.51 ENST00000369801.1
CSF1
colony stimulating factor 1 (macrophage)
chr3_+_122283175 1.51 ENST00000383661.3
DTX3L
deltex 3-like (Drosophila)
chr21_-_16135411 1.49 ENST00000435315.2
AF127936.5
AF127936.5
chr19_+_17516531 1.48 ENST00000528911.1
ENST00000528604.1
ENST00000595892.1
ENST00000500836.2
ENST00000598546.1
ENST00000600369.1
ENST00000598356.1
ENST00000594426.1
MVB12A
CTD-2521M24.9
multivesicular body subunit 12A
CTD-2521M24.9
chr11_-_57335280 1.46 ENST00000287156.4
UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr11_-_2160180 1.41 ENST00000381406.4
IGF2
insulin-like growth factor 2 (somatomedin A)
chr17_+_4643337 1.40 ENST00000592813.1
ZMYND15
zinc finger, MYND-type containing 15
chr3_-_49851313 1.37 ENST00000333486.3
UBA7
ubiquitin-like modifier activating enzyme 7
chr11_+_72983246 1.36 ENST00000393590.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr3_-_146262428 1.36 ENST00000486631.1
PLSCR1
phospholipid scramblase 1
chr3_+_122283064 1.35 ENST00000296161.4
DTX3L
deltex 3-like (Drosophila)
chr3_+_122399444 1.35 ENST00000474629.2
PARP14
poly (ADP-ribose) polymerase family, member 14
chr17_+_41363854 1.34 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
TMEM106A
transmembrane protein 106A
chr11_-_62607036 1.33 ENST00000311713.7
ENST00000278856.4
WDR74
WD repeat domain 74
chr8_+_72755367 1.31 ENST00000537896.1
RP11-383H13.1
Protein LOC100132891; cDNA FLJ53548
chr17_-_43339453 1.29 ENST00000543122.1
SPATA32
spermatogenesis associated 32
chr9_-_33402506 1.26 ENST00000377425.4
ENST00000537089.1
ENST00000297988.1
ENST00000539936.1
ENST00000541274.1
AQP7
aquaporin 7
chr5_-_159797627 1.24 ENST00000393975.3
C1QTNF2
C1q and tumor necrosis factor related protein 2
chr1_-_89531041 1.23 ENST00000370473.4
GBP1
guanylate binding protein 1, interferon-inducible
chr19_+_36239576 1.23 ENST00000587751.1
LIN37
lin-37 homolog (C. elegans)
chr11_-_321340 1.22 ENST00000526811.1
IFITM3
interferon induced transmembrane protein 3
chr3_-_146262488 1.19 ENST00000487389.1
PLSCR1
phospholipid scramblase 1
chr9_+_74764278 1.18 ENST00000238018.4
ENST00000376989.3
GDA
guanine deaminase
chr6_-_32806483 1.18 ENST00000374899.4
TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr3_-_146262365 1.17 ENST00000448787.2
PLSCR1
phospholipid scramblase 1
chr9_-_100881466 1.17 ENST00000341469.2
ENST00000342043.3
ENST00000375098.3
TRIM14
tripartite motif containing 14
chr8_+_39770803 1.17 ENST00000518237.1
IDO1
indoleamine 2,3-dioxygenase 1
chr6_-_29527702 1.14 ENST00000377050.4
UBD
ubiquitin D
chr1_-_161039647 1.14 ENST00000368013.3
ARHGAP30
Rho GTPase activating protein 30
chr1_+_110453203 1.13 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1
colony stimulating factor 1 (macrophage)
chr19_+_10196781 1.12 ENST00000253110.11
C19orf66
chromosome 19 open reading frame 66
chr6_+_3259122 1.12 ENST00000438998.2
ENST00000380305.4
PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr22_-_36635598 1.10 ENST00000454728.1
APOL2
apolipoprotein L, 2
chr1_-_161039753 1.08 ENST00000368015.1
ARHGAP30
Rho GTPase activating protein 30
chr11_+_5710919 1.07 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chr20_-_47894936 1.07 ENST00000371754.4
ZNFX1
zinc finger, NFX1-type containing 1
chr20_+_6748311 1.06 ENST00000378827.4
BMP2
bone morphogenetic protein 2
chr12_+_102271436 1.06 ENST00000544152.1
DRAM1
DNA-damage regulated autophagy modulator 1
chr15_+_74287118 1.04 ENST00000563500.1
PML
promyelocytic leukemia
chr22_-_50765489 1.04 ENST00000413817.3
DENND6B
DENN/MADD domain containing 6B
chr17_-_4642429 1.04 ENST00000573123.1
CXCL16
chemokine (C-X-C motif) ligand 16
chr16_-_74734672 1.03 ENST00000306247.7
ENST00000575686.1
MLKL
mixed lineage kinase domain-like
chr9_-_21368075 1.02 ENST00000449498.1
IFNA13
interferon, alpha 13
chr14_-_69445968 1.00 ENST00000438964.2
ACTN1
actinin, alpha 1
chr16_-_88851618 1.00 ENST00000301015.9
PIEZO1
piezo-type mechanosensitive ion channel component 1
chr11_-_47270341 0.99 ENST00000529444.1
ENST00000530453.1
ENST00000537863.1
ENST00000529788.1
ENST00000444355.2
ENST00000527256.1
ENST00000529663.1
ENST00000256997.3
ACP2
acid phosphatase 2, lysosomal
chr2_+_33701684 0.99 ENST00000442390.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr17_-_54991369 0.99 ENST00000537230.1
TRIM25
tripartite motif containing 25
chr17_+_41158742 0.96 ENST00000415816.2
ENST00000438323.2
IFI35
interferon-induced protein 35
chr2_-_152118276 0.96 ENST00000409092.1
RBM43
RNA binding motif protein 43
chr4_-_169401628 0.96 ENST00000514748.1
ENST00000512371.1
ENST00000260184.7
ENST00000505890.1
ENST00000511577.1
DDX60L
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
chr1_+_158901329 0.95 ENST00000368140.1
ENST00000368138.3
ENST00000392254.2
ENST00000392252.3
ENST00000368135.4
PYHIN1
pyrin and HIN domain family, member 1
chr13_+_50070491 0.94 ENST00000496612.1
ENST00000357596.3
ENST00000485919.1
ENST00000442195.1
PHF11
PHD finger protein 11
chr14_-_69446034 0.94 ENST00000193403.6
ACTN1
actinin, alpha 1
chr14_-_21562671 0.93 ENST00000554923.1
ZNF219
zinc finger protein 219
chr3_+_121289551 0.93 ENST00000334384.3
ARGFX
arginine-fifty homeobox
chr7_+_42971799 0.93 ENST00000223324.2
MRPL32
mitochondrial ribosomal protein L32
chr5_-_66942617 0.92 ENST00000507298.1
RP11-83M16.5
RP11-83M16.5
chr18_+_3466248 0.91 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
RP11-838N2.4
chr9_+_108424738 0.91 ENST00000334077.3
TAL2
T-cell acute lymphocytic leukemia 2
chr20_-_47894569 0.91 ENST00000371744.1
ENST00000371752.1
ENST00000396105.1
ZNFX1
zinc finger, NFX1-type containing 1
chr11_-_64647144 0.91 ENST00000359393.2
ENST00000433803.1
ENST00000411683.1
EHD1
EH-domain containing 1
chr9_+_26746951 0.91 ENST00000523363.1
RP11-18A15.1
RP11-18A15.1
chr3_+_122399697 0.91 ENST00000494811.1
PARP14
poly (ADP-ribose) polymerase family, member 14
chr17_-_4167142 0.89 ENST00000570535.1
ENST00000574367.1
ENST00000341657.4
ENST00000433651.1
ANKFY1
ankyrin repeat and FYVE domain containing 1
chr22_-_36600727 0.88 ENST00000397275.2
ENST00000328429.4
APOL4
apolipoprotein L, 4
chr7_-_77045617 0.87 ENST00000257626.7
GSAP
gamma-secretase activating protein
chr1_-_161014731 0.87 ENST00000368020.1
USF1
upstream transcription factor 1
chr18_+_55712915 0.87 ENST00000592846.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr6_-_27775694 0.87 ENST00000377401.2
HIST1H2BL
histone cluster 1, H2bl
chr19_+_49977818 0.86 ENST00000594009.1
ENST00000595510.1
FLT3LG
fms-related tyrosine kinase 3 ligand
chr22_+_36649170 0.85 ENST00000438034.1
ENST00000427990.1
ENST00000347595.7
ENST00000397279.4
ENST00000433768.1
ENST00000440669.2
APOL1
apolipoprotein L, 1
chr11_+_34663913 0.84 ENST00000532302.1
EHF
ets homologous factor
chr12_-_24737089 0.84 ENST00000483544.1
LINC00477
long intergenic non-protein coding RNA 477
chr7_-_47621229 0.83 ENST00000434451.1
TNS3
tensin 3
chr16_-_67970990 0.83 ENST00000358514.4
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr7_+_18535321 0.82 ENST00000413380.1
ENST00000430454.1
HDAC9
histone deacetylase 9
chr8_+_143808605 0.82 ENST00000336138.3
THEM6
thioesterase superfamily member 6
chr22_-_30234218 0.81 ENST00000307790.3
ENST00000542393.1
ENST00000397771.2
ASCC2
activating signal cointegrator 1 complex subunit 2
chr2_+_201981119 0.81 ENST00000395148.2
CFLAR
CASP8 and FADD-like apoptosis regulator
chr11_+_59705928 0.81 ENST00000398992.1
OOSP1
oocyte secreted protein 1
chr10_-_135187193 0.79 ENST00000368547.3
ECHS1
enoyl CoA hydratase, short chain, 1, mitochondrial
chr6_-_32806506 0.79 ENST00000374897.2
ENST00000452392.2
TAP2
TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Uncharacterized protein
chr17_+_46918925 0.79 ENST00000502761.1
CALCOCO2
calcium binding and coiled-coil domain 2
chr6_+_26273144 0.78 ENST00000377733.2
HIST1H2BI
histone cluster 1, H2bi
chr7_+_18535893 0.78 ENST00000432645.2
ENST00000441542.2
HDAC9
histone deacetylase 9
chr5_-_95158644 0.78 ENST00000237858.6
GLRX
glutaredoxin (thioltransferase)
chr1_-_154580616 0.78 ENST00000368474.4
ADAR
adenosine deaminase, RNA-specific
chr10_-_128077024 0.77 ENST00000368679.4
ENST00000368676.4
ENST00000448723.1
ADAM12
ADAM metallopeptidase domain 12
chr11_-_4414880 0.75 ENST00000254436.7
ENST00000543625.1
TRIM21
tripartite motif containing 21
chr17_-_74489215 0.75 ENST00000585701.1
ENST00000591192.1
ENST00000589526.1
RHBDF2
rhomboid 5 homolog 2 (Drosophila)
chr7_-_76955563 0.75 ENST00000441833.2
GSAP
gamma-secretase activating protein
chr19_+_17516909 0.74 ENST00000601007.1
ENST00000594913.1
ENST00000599975.1
ENST00000600514.1
CTD-2521M24.9
MVB12A
CTD-2521M24.9
multivesicular body subunit 12A
chr2_-_220252530 0.74 ENST00000521459.1
DNPEP
aspartyl aminopeptidase
chr14_+_24605361 0.74 ENST00000206451.6
ENST00000559123.1
PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr21_+_43933946 0.73 ENST00000352133.2
SLC37A1
solute carrier family 37 (glucose-6-phosphate transporter), member 1
chr11_+_5711010 0.73 ENST00000454828.1
TRIM22
tripartite motif containing 22
chr7_-_112635675 0.73 ENST00000447785.1
ENST00000451962.1
AC018464.3
AC018464.3
chr11_+_308143 0.73 ENST00000399817.4
IFITM2
interferon induced transmembrane protein 2
chr22_-_36635563 0.72 ENST00000451256.2
APOL2
apolipoprotein L, 2
chr7_+_150382781 0.72 ENST00000223293.5
ENST00000474605.1
GIMAP2
GTPase, IMAP family member 2
chr1_-_206306107 0.72 ENST00000436158.1
ENST00000455672.1
RP11-38J22.6
RP11-38J22.6
chr11_-_18343669 0.72 ENST00000396253.3
ENST00000349215.3
ENST00000438420.2
HPS5
Hermansky-Pudlak syndrome 5
chr8_-_27941380 0.72 ENST00000413272.2
ENST00000341513.6
NUGGC
nuclear GTPase, germinal center associated
chr6_+_62284008 0.71 ENST00000544932.1
MTRNR2L9
MT-RNR2-like 9 (pseudogene)
chr3_-_146262293 0.70 ENST00000448205.1
PLSCR1
phospholipid scramblase 1
chr4_+_154622652 0.70 ENST00000260010.6
TLR2
toll-like receptor 2
chr4_+_156587853 0.69 ENST00000506455.1
ENST00000511108.1
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr12_+_48876275 0.69 ENST00000314014.2
C12orf54
chromosome 12 open reading frame 54
chr11_+_308217 0.68 ENST00000602569.1
IFITM2
interferon induced transmembrane protein 2
chr6_-_11232891 0.68 ENST00000379433.5
ENST00000379446.5
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr14_-_24615805 0.68 ENST00000560410.1
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr1_+_158149737 0.67 ENST00000368171.3
CD1D
CD1d molecule
chr1_-_198906528 0.67 ENST00000432296.1
MIR181A1HG
MIR181A1 host gene (non-protein coding)
chr21_-_37451680 0.67 ENST00000399201.1
SETD4
SET domain containing 4
chr10_-_99161033 0.67 ENST00000315563.6
ENST00000370992.4
ENST00000414986.1
RRP12
ribosomal RNA processing 12 homolog (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 14.2 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
2.5 7.5 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731)
2.1 8.6 GO:0051097 negative regulation of helicase activity(GO:0051097)
2.1 44.4 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
2.0 22.2 GO:0018377 protein myristoylation(GO:0018377)
1.4 7.2 GO:0035549 positive regulation of interferon-beta secretion(GO:0035549)
1.4 16.8 GO:0060700 regulation of ribonuclease activity(GO:0060700)
1.4 5.4 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
1.2 6.2 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
1.1 12.0 GO:1904180 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
1.0 12.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
1.0 2.9 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361) natural killer cell tolerance induction(GO:0002519) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562) positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
1.0 3.8 GO:0046967 cytosol to ER transport(GO:0046967)
0.9 4.6 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.8 10.1 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.8 3.9 GO:0060611 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) positive regulation of microglial cell migration(GO:1904141)
0.8 11.5 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.8 7.6 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.7 11.2 GO:0010818 T cell chemotaxis(GO:0010818)
0.6 62.2 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.6 1.7 GO:0006147 guanine catabolic process(GO:0006147)
0.5 2.1 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.5 3.1 GO:2000836 androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
0.5 0.5 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.5 1.0 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.4 3.4 GO:0030578 PML body organization(GO:0030578)
0.4 2.3 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.4 1.1 GO:0060129 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) regulation of calcium-independent cell-cell adhesion(GO:0051040) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.3 1.3 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.3 2.2 GO:0019075 virus maturation(GO:0019075)
0.3 0.9 GO:0050823 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.3 1.2 GO:0036269 swimming behavior(GO:0036269)
0.3 0.8 GO:0006624 vacuolar protein processing(GO:0006624)
0.3 4.7 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.3 1.1 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.3 0.3 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.3 3.8 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 1.0 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.2 0.7 GO:1990108 protein linear deubiquitination(GO:1990108)
0.2 0.6 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.2 1.2 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.2 0.8 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.2 2.3 GO:1903944 negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2 5.9 GO:0008053 mitochondrial fusion(GO:0008053)
0.2 0.9 GO:0002906 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.2 0.5 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685) operant conditioning(GO:0035106)
0.2 0.3 GO:1903216 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.2 0.2 GO:0001302 replicative cell aging(GO:0001302)
0.2 0.5 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.2 1.3 GO:0015793 glycerol transport(GO:0015793)
0.2 0.8 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.2 2.8 GO:0043248 proteasome assembly(GO:0043248)
0.2 0.3 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.1 0.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.9 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 2.4 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 0.3 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 0.4 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 0.8 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 0.4 GO:0036451 cap mRNA methylation(GO:0036451)
0.1 0.4 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 0.7 GO:0021623 optic cup structural organization(GO:0003409) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.1 1.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 12.6 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.1 0.4 GO:0006481 C-terminal protein methylation(GO:0006481)
0.1 0.7 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 1.4 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 1.1 GO:0070842 aggresome assembly(GO:0070842)
0.1 0.9 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.1 0.4 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.1 3.2 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.1 0.7 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
0.1 2.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.2 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.1 0.6 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.1 0.5 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 0.3 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.1 0.2 GO:0003051 brain renin-angiotensin system(GO:0002035) angiotensin-mediated drinking behavior(GO:0003051)
0.1 0.4 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110)
0.1 0.3 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 1.4 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 1.6 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 0.6 GO:0007320 insemination(GO:0007320)
0.1 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 1.3 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.1 2.0 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 0.5 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.2 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 0.3 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.1 0.2 GO:0006059 hexitol metabolic process(GO:0006059)
0.1 0.4 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.3 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 0.4 GO:0015692 lead ion transport(GO:0015692)
0.1 0.2 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.6 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.3 GO:1990927 calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.1 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.1 1.9 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.3 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.1 0.6 GO:0043473 pigmentation(GO:0043473)
0.1 0.2 GO:0045113 regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.1 0.3 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.1 0.3 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.5 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.5 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.1 0.5 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.4 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.3 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 0.3 GO:1902728 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.1 1.1 GO:0021794 thalamus development(GO:0021794)
0.1 1.9 GO:0002360 T cell lineage commitment(GO:0002360)
0.1 0.3 GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1 0.2 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.1 0.4 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 0.2 GO:0061373 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 1.2 GO:0051798 positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.1 0.5 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.2 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.2 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.1 0.4 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.4 GO:0033590 response to cobalamin(GO:0033590) response to erythropoietin(GO:0036017) cellular response to erythropoietin(GO:0036018)
0.1 0.4 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 0.4 GO:0050955 thermoception(GO:0050955)
0.1 1.4 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.1 0.9 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.3 GO:1901526 negative regulation of mitochondrial membrane permeability(GO:0035795) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1 0.2 GO:0045208 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.1 2.0 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 1.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 3.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.7 GO:0050709 negative regulation of protein secretion(GO:0050709)
0.0 13.0 GO:0051607 defense response to virus(GO:0051607)
0.0 0.3 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.7 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.7 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 1.4 GO:0007567 parturition(GO:0007567)
0.0 3.7 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.0 0.1 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.2 GO:0001507 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0 0.1 GO:1990737 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.2 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.2 GO:0021678 third ventricle development(GO:0021678)
0.0 0.8 GO:0021930 cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.0 0.1 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.3 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.2 GO:0048690 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.0 0.2 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 0.0 GO:0002838 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859)
0.0 0.6 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 1.5 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.1 GO:0033037 polysaccharide localization(GO:0033037)
0.0 0.2 GO:0060290 transdifferentiation(GO:0060290)
0.0 1.2 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.3 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.0 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.1 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.3 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.8 GO:0050798 activated T cell proliferation(GO:0050798)
0.0 0.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.6 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.1 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.0 0.3 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.2 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0 1.9 GO:0050918 positive chemotaxis(GO:0050918)
0.0 0.1 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.2 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.7 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.3 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:2000769 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.3 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.2 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.1 GO:1902080 negative regulation of calcium-transporting ATPase activity(GO:1901895) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.0 0.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.3 GO:0035973 aggrephagy(GO:0035973)
0.0 0.2 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.3 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.5 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.2 GO:1902416 regulation of mRNA binding(GO:1902415) positive regulation of mRNA binding(GO:1902416)
0.0 0.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.3 GO:0014029 neural crest formation(GO:0014029)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.3 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.1 GO:0019858 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966) cytosine metabolic process(GO:0019858)
0.0 0.8 GO:0034728 nucleosome organization(GO:0034728)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.5 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 0.1 GO:0097152 mesenchymal cell apoptotic process(GO:0097152)
0.0 0.1 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 0.7 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.2 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0070904 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.2 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.2 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.1 GO:0035989 tendon development(GO:0035989)
0.0 0.2 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.1 GO:0060167 regulation of adenosine receptor signaling pathway(GO:0060167)
0.0 0.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.2 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.1 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.1 GO:1904764 vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0042335 cuticle development(GO:0042335)
0.0 0.1 GO:0060529 ectoderm and mesoderm interaction(GO:0007499) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
0.0 1.3 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.2 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.2 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.7 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.2 GO:0060022 hard palate development(GO:0060022)
0.0 0.2 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.3 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.2 GO:0006559 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.1 GO:0072343 pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.2 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0048839 inner ear development(GO:0048839)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:2000134 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.3 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0 0.3 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772) thiamine diphosphate metabolic process(GO:0042357)
0.0 0.1 GO:0009988 cell-cell recognition(GO:0009988)
0.0 0.1 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.3 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.2 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.3 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.6 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.5 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.0 0.5 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.3 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.0 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.5 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.3 GO:0006825 copper ion transport(GO:0006825)
0.0 0.0 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.0 0.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.5 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 14.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.7 4.8 GO:0042825 TAP complex(GO:0042825)
0.6 3.9 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.5 3.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.4 2.2 GO:0008537 proteasome activator complex(GO:0008537)
0.2 1.0 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.2 24.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.2 0.6 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.2 1.9 GO:0032010 phagolysosome(GO:0032010)
0.2 7.8 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.2 1.2 GO:0036021 endolysosome lumen(GO:0036021)
0.2 0.6 GO:0031084 BLOC-2 complex(GO:0031084)
0.2 0.9 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 0.8 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 2.2 GO:0000813 ESCRT I complex(GO:0000813)
0.1 9.0 GO:0005771 multivesicular body(GO:0005771)
0.1 0.3 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.1 15.2 GO:0005643 nuclear pore(GO:0005643)
0.1 2.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 1.1 GO:0016589 NURF complex(GO:0016589)
0.1 0.5 GO:0071547 piP-body(GO:0071547)
0.1 0.3 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 1.2 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.3 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.9 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.3 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 0.3 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.1 0.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 6.2 GO:0015030 Cajal body(GO:0015030)
0.1 1.4 GO:0005916 fascia adherens(GO:0005916)
0.1 0.4 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 2.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 29.1 GO:0031965 nuclear membrane(GO:0031965)
0.1 0.4 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.8 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.9 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.7 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.2 GO:0097444 spine apparatus(GO:0097444)
0.1 0.2 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.8 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 1.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.2 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 0.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 1.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 1.3 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 1.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 1.4 GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.4 GO:0070552 BRISC complex(GO:0070552)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0042382 paraspeckles(GO:0042382)
0.0 0.9 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.6 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0071020 post-spliceosomal complex(GO:0071020)
0.0 0.3 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 1.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.3 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.6 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 69.3 GO:0005739 mitochondrion(GO:0005739)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.3 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.3 GO:0097443 sorting endosome(GO:0097443)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0042022 interleukin-12 receptor complex(GO:0042022)
0.0 0.8 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0001520 outer dense fiber(GO:0001520)
0.0 1.3 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 1.1 GO:0016235 aggresome(GO:0016235)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 2.2 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.7 GO:0070822 Sin3-type complex(GO:0070822)
0.0 3.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 2.4 GO:0072562 blood microparticle(GO:0072562)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.4 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 1.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.2 GO:0032009 early phagosome(GO:0032009)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.9 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.4 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.9 GO:0005811 lipid particle(GO:0005811)
0.0 4.9 GO:0045121 membrane raft(GO:0045121)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 6.5 GO:0010008 endosome membrane(GO:0010008)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.5 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 48.0 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
1.5 4.6 GO:0008859 exoribonuclease II activity(GO:0008859)
1.1 4.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.7 26.9 GO:0005521 lamin binding(GO:0005521)
0.6 5.5 GO:0046977 TAP binding(GO:0046977) TAP1 binding(GO:0046978)
0.6 7.5 GO:0031386 protein tag(GO:0031386)
0.6 1.7 GO:0008892 guanine deaminase activity(GO:0008892)
0.6 3.9 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.5 2.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.5 2.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.5 3.1 GO:0004882 androgen receptor activity(GO:0004882)
0.4 12.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.4 2.9 GO:0005534 galactose binding(GO:0005534)
0.4 1.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.4 7.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.3 3.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.3 1.7 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.3 8.5 GO:0070403 NAD+ binding(GO:0070403)
0.3 5.9 GO:0051400 BH domain binding(GO:0051400)
0.3 1.3 GO:0015254 glycerol channel activity(GO:0015254)
0.3 7.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 6.9 GO:0008009 chemokine activity(GO:0008009)
0.2 2.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 3.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.2 1.1 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.2 1.7 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 0.8 GO:1902379 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.2 1.7 GO:0071723 lipopeptide binding(GO:0071723)
0.2 1.4 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.2 0.5 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.2 3.8 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.2 0.5 GO:0004995 tachykinin receptor activity(GO:0004995)
0.2 0.6 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.2 1.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.4 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 1.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.4 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.1 0.8 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 16.6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 1.1 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.4 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 67.3 GO:0005525 GTP binding(GO:0005525)
0.1 1.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 12.2 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 0.5 GO:0034584 piRNA binding(GO:0034584)
0.1 3.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.6 GO:0045569 TRAIL binding(GO:0045569)
0.1 0.5 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.8 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 3.1 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.0 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.3 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.1 0.3 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 1.3 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.5 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.3 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.4 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.2 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.4 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 1.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 1.0 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 2.4 GO:0031078 NAD-dependent histone deacetylase activity(GO:0017136) histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) NAD-dependent protein deacetylase activity(GO:0034979)
0.1 1.0 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 0.4 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 0.7 GO:0015288 porin activity(GO:0015288)
0.1 0.2 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.1 0.2 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 1.9 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 0.7 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 2.3 GO:0005123 death receptor binding(GO:0005123)
0.1 0.3 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.8 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 0.8 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 1.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.2 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.1 0.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 1.0 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.5 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 3.0 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.5 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.0 0.1 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 1.0 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.5 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.9 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.1 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.0 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 2.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.3 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.2 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 4.2 GO:0046332 SMAD binding(GO:0046332)
0.0 1.4 GO:0030546 receptor activator activity(GO:0030546)
0.0 0.2 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.6 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.6 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.6 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.2 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 2.1 GO:0001047 core promoter binding(GO:0001047)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 1.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0016517 interleukin-12 receptor activity(GO:0016517)
0.0 0.1 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.3 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.1 GO:0042007 interleukin-18 binding(GO:0042007)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.2 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.4 GO:0070330 aromatase activity(GO:0070330)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 1.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 1.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 2.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.2 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.0 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 1.0 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.5 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.5 GO:0004984 olfactory receptor activity(GO:0004984)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.0 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 19.6 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 2.8 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 6.0 PID BCR 5PATHWAY BCR signaling pathway
0.1 12.0 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 4.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 0.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 0.5 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 3.6 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 2.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 3.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 2.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 2.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 211.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.6 9.1 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.2 11.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 12.9 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.2 4.7 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 2.4 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.1 6.2 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 10.5 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.1 1.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.0 REACTOME DEFENSINS Genes involved in Defensins
0.1 2.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.7 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 3.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 0.5 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 0.8 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.1 1.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.9 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.6 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 2.3 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 1.1 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.7 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.8 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.1 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.3 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.2 REACTOME INTERFERON SIGNALING Genes involved in Interferon Signaling
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation