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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HSFY2

Z-value: 0.92

Motif logo

Transcription factors associated with HSFY2

Gene Symbol Gene ID Gene Info
ENSG00000169953.11 heat shock transcription factor Y-linked 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HSFY2hg19_v2_chrY_-_20935572_209356210.473.4e-01Click!

Activity profile of HSFY2 motif

Sorted Z-values of HSFY2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_80263506 0.64 ENST00000335661.6
BCL2-related protein A1
chr6_+_63921351 0.45 ENST00000370659.1
FK506 binding protein 1C
chr1_-_94344686 0.41 ENST00000528680.1
deoxynucleotidyltransferase, terminal, interacting protein 2
chr13_+_20268547 0.41 ENST00000601204.1
AL354808.2
chr1_-_89458287 0.36 ENST00000370485.2
cysteine conjugate-beta lyase 2
chr10_+_35416223 0.35 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
cAMP responsive element modulator
chr9_-_25678856 0.35 ENST00000358022.3
tumor suppressor candidate 1
chr1_-_89458415 0.34 ENST00000321792.5
ENST00000370491.3
RNA binding motif protein, X-linked-like 1
cysteine conjugate-beta lyase 2
chr3_+_145782358 0.34 ENST00000422482.1
HCG1786590; PRO2533; Uncharacterized protein
chr2_-_169769787 0.33 ENST00000451987.1
SPC25, NDC80 kinetochore complex component
chr7_-_91509972 0.33 ENST00000425936.1
mitochondrial transcription termination factor
chr11_+_125757556 0.32 ENST00000526028.1
hydrolethalus syndrome 1
chr12_+_27619743 0.32 ENST00000298876.4
ENST00000416383.1
single-pass membrane protein with coiled-coil domains 2
chr12_-_100486668 0.32 ENST00000550544.1
ENST00000551980.1
ENST00000548045.1
ENST00000545232.2
ENST00000551973.1
UHRF1 binding protein 1-like
chr15_+_45694567 0.32 ENST00000559860.1
spermatogenesis associated 5-like 1
chr7_-_35840198 0.32 ENST00000412856.1
ENST00000437235.3
ENST00000424194.1
AC007551.3
chr5_+_68485363 0.31 ENST00000283006.2
ENST00000515001.1
centromere protein H
chr4_+_146402346 0.31 ENST00000514778.1
ENST00000507594.1
SMAD family member 1
chr14_+_21525981 0.30 ENST00000308227.2
ribonuclease, RNase A family, 8
chr6_-_73935163 0.30 ENST00000370388.3
KH homology domain containing 1-like
chr1_-_197115818 0.29 ENST00000367409.4
ENST00000294732.7
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr15_+_96904487 0.29 ENST00000600790.1
Uncharacterized protein
chr15_-_35280426 0.28 ENST00000559564.1
ENST00000356321.4
zinc finger protein 770
chr14_+_39944025 0.28 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
chr16_-_18923035 0.27 ENST00000563836.1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr8_+_120428546 0.27 ENST00000259526.3
nephroblastoma overexpressed
chr3_-_186262166 0.27 ENST00000307944.5
crystallin, gamma S
chr3_-_165555200 0.27 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
butyrylcholinesterase
chr7_+_99425633 0.26 ENST00000354829.2
ENST00000421837.2
ENST00000417625.1
ENST00000342499.4
ENST00000444905.1
ENST00000415413.1
ENST00000312017.5
ENST00000222382.5
cytochrome P450, family 3, subfamily A, polypeptide 43
chr14_+_39583427 0.26 ENST00000308317.6
ENST00000396249.2
ENST00000250379.8
ENST00000534684.2
ENST00000527381.1
gem (nuclear organelle) associated protein 2
chr1_+_234509413 0.26 ENST00000366613.1
ENST00000366612.1
cytochrome c oxidase assembly factor 6 homolog (S. cerevisiae)
chr3_-_129375556 0.26 ENST00000510323.1
transmembrane and coiled-coil domain family 1
chr19_-_43421989 0.25 ENST00000292125.2
ENST00000187910.2
pregnancy specific beta-1-glycoprotein 6
chr6_-_107077347 0.25 ENST00000369063.3
ENST00000539449.1
reticulon 4 interacting protein 1
chr2_+_74056147 0.25 ENST00000394070.2
ENST00000536064.1
STAM binding protein
chr6_-_72129806 0.24 ENST00000413945.1
ENST00000602878.1
ENST00000436803.1
ENST00000421704.1
ENST00000441570.1
long intergenic non-protein coding RNA 472
chr8_-_61429315 0.24 ENST00000530725.1
ENST00000532232.1
RP11-163N6.2
chr10_-_104866395 0.24 ENST00000458345.1
5'-nucleotidase, cytosolic II
chr10_-_90611566 0.23 ENST00000371930.4
ankyrin repeat domain 22
chr14_+_22600515 0.23 ENST00000390456.3
T cell receptor alpha variable 8-7 (non-functional)
chr2_+_181988620 0.23 ENST00000428474.1
ENST00000424655.1
AC104820.2
chr6_-_26033796 0.23 ENST00000259791.2
histone cluster 1, H2ab
chr5_+_68485433 0.22 ENST00000502689.1
centromere protein H
chr2_+_74056066 0.22 ENST00000339566.3
ENST00000409707.1
ENST00000452725.1
ENST00000432295.2
ENST00000424659.1
ENST00000394073.1
STAM binding protein
chrX_+_155110956 0.22 ENST00000286448.6
ENST00000262640.6
ENST00000460621.1
vesicle-associated membrane protein 7
chr3_-_20227619 0.22 ENST00000425061.1
ENST00000443724.1
ENST00000421451.1
ENST00000452020.1
ENST00000417364.1
ENST00000306698.2
ENST00000419233.2
ENST00000263753.4
ENST00000383774.1
ENST00000437051.1
ENST00000412868.1
ENST00000429446.3
ENST00000442720.1
shugoshin-like 1 (S. pombe)
chr9_-_79009414 0.22 ENST00000376736.1
riboflavin kinase
chr9_+_116343192 0.22 ENST00000471324.2
regulator of G-protein signaling 3
chr18_+_57567180 0.22 ENST00000316660.6
ENST00000269518.9
phorbol-12-myristate-13-acetate-induced protein 1
chr5_+_667759 0.22 ENST00000594226.1
Uncharacterized protein
chr19_-_33182616 0.22 ENST00000592431.1
CTD-2538C1.2
chr10_-_105110890 0.21 ENST00000369847.3
polycomb group ring finger 6
chr18_+_39535152 0.21 ENST00000262039.4
ENST00000398870.3
ENST00000586545.1
phosphatidylinositol 3-kinase, catalytic subunit type 3
chr20_+_62697564 0.21 ENST00000458442.1
transcription elongation factor A (SII), 2
chr4_+_130017268 0.21 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
chromosome 4 open reading frame 33
chr12_-_111142729 0.20 ENST00000546713.1
hydrogen voltage-gated channel 1
chr3_+_186383741 0.20 ENST00000232003.4
histidine-rich glycoprotein
chr13_-_30160925 0.20 ENST00000450494.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr2_-_27435634 0.20 ENST00000430186.1
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chrX_+_100353153 0.20 ENST00000423383.1
ENST00000218507.5
ENST00000403304.2
ENST00000435570.1
centromere protein I
chr7_+_79764104 0.20 ENST00000351004.3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr1_-_38157877 0.19 ENST00000477060.1
ENST00000491981.1
ENST00000488137.1
chromosome 1 open reading frame 109
chr9_+_131901710 0.19 ENST00000524946.2
protein phosphatase 2A activator, regulatory subunit 4
chr1_-_53163992 0.19 ENST00000371538.3
cytochrome c oxidase assembly factor 7
chr3_-_155011483 0.19 ENST00000489090.1
RP11-451G4.2
chr1_-_226496898 0.19 ENST00000481685.1
lin-9 homolog (C. elegans)
chr1_-_222763240 0.18 ENST00000352967.4
ENST00000391882.1
ENST00000543857.1
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
chr15_-_57025759 0.18 ENST00000267807.7
zinc finger protein 280D
chr5_+_68860949 0.18 ENST00000507595.1
general transcription factor IIH, polypeptide 2C
chr17_+_68047418 0.18 ENST00000586373.1
ENST00000588782.1
long intergenic non-protein coding RNA 1028
chr3_+_3168600 0.18 ENST00000251607.6
ENST00000339437.6
ENST00000280591.6
ENST00000420393.1
tRNA nucleotidyl transferase, CCA-adding, 1
chr6_+_26538566 0.18 ENST00000377575.2
high mobility group nucleosomal binding domain 4
chr12_+_66217911 0.18 ENST00000403681.2
high mobility group AT-hook 2
chr7_+_23637763 0.18 ENST00000410069.1
coiled-coil domain containing 126
chr5_-_37371278 0.17 ENST00000231498.3
nucleoporin 155kDa
chr10_-_95462265 0.17 ENST00000536233.1
ENST00000359204.4
ENST00000371430.2
ENST00000394100.2
fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1
chr18_+_39535239 0.17 ENST00000585528.1
phosphatidylinositol 3-kinase, catalytic subunit type 3
chr12_+_117013656 0.17 ENST00000556529.1
microtubule-associated protein 1 light chain 3 beta 2
chr18_-_61329118 0.17 ENST00000332821.8
ENST00000283752.5
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr11_+_17281900 0.17 ENST00000530527.1
nucleobindin 2
chrX_+_21857717 0.17 ENST00000379484.5
membrane-bound transcription factor peptidase, site 2
chr6_+_160211481 0.16 ENST00000367034.4
mitochondrial ribosomal protein L18
chrX_+_52841228 0.16 ENST00000351072.1
ENST00000425386.1
ENST00000375503.3
X antigen family, member 5
chr1_-_52456352 0.16 ENST00000371655.3
RAB3B, member RAS oncogene family
chr19_-_1876156 0.16 ENST00000565797.1
CTB-31O20.2
chr10_+_105881779 0.16 ENST00000369729.3
SWI5-dependent recombination repair 1
chr8_+_144120648 0.16 ENST00000395172.1
chromosome 8 open reading frame 31
chr8_+_48920960 0.16 ENST00000523111.2
ENST00000523432.1
ENST00000521346.1
ENST00000517630.1
ubiquitin-conjugating enzyme E2 variant 2
chr6_+_53976285 0.16 ENST00000514433.1
muscular LMNA-interacting protein
chr15_+_45694523 0.16 ENST00000305560.6
spermatogenesis associated 5-like 1
chr4_-_68995571 0.16 ENST00000356291.2
transmembrane protease, serine 11F
chr3_+_138067314 0.16 ENST00000423968.2
muscle RAS oncogene homolog
chr1_-_110950255 0.15 ENST00000483260.1
ENST00000474861.2
ENST00000602318.1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
chr8_-_120259055 0.15 ENST00000522828.1
ENST00000523307.1
ENST00000524129.1
ENST00000521048.1
ENST00000522187.1
RP11-4K16.2
chr19_-_52489923 0.15 ENST00000593596.1
ENST00000243644.4
ENST00000594929.1
ENST00000601430.1
zinc finger protein 350
chr1_+_93646238 0.15 ENST00000448243.1
ENST00000370276.1
coiled-coil domain containing 18
chr4_-_68749699 0.15 ENST00000545541.1
transmembrane protease, serine 11D
chr7_+_105172532 0.15 ENST00000257700.2
RAD50 interactor 1
chr11_-_92930556 0.15 ENST00000529184.1
solute carrier family 36 (proton/amino acid symporter), member 4
chr14_+_104394770 0.15 ENST00000409874.4
ENST00000339063.5
tudor domain containing 9
chr11_+_102980126 0.15 ENST00000375735.2
dynein, cytoplasmic 2, heavy chain 1
chr14_-_39639523 0.15 ENST00000330149.5
ENST00000554018.1
ENST00000347691.5
trafficking protein particle complex 6B
chr12_-_8088773 0.15 ENST00000544291.1
solute carrier family 2 (facilitated glucose transporter), member 3
chr17_-_46178741 0.15 ENST00000581003.1
ENST00000225603.4
chromobox homolog 1
chr19_+_36705504 0.15 ENST00000456324.1
zinc finger protein 146
chr6_-_26285737 0.14 ENST00000377727.1
ENST00000289352.1
histone cluster 1, H4h
chr3_-_64431146 0.14 ENST00000569824.1
ENST00000485770.1
prickle homolog 2 (Drosophila)
RP11-14D22.2
chr13_-_34250861 0.14 ENST00000445227.1
ENST00000454681.2
RP11-141M1.3
chr3_+_25831567 0.14 ENST00000280701.3
ENST00000420173.2
3-oxoacyl-ACP synthase, mitochondrial
chr3_-_148804275 0.14 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
helicase-like transcription factor
chr12_-_21910775 0.14 ENST00000539782.1
lactate dehydrogenase B
chr8_+_59323823 0.14 ENST00000399598.2
UBX domain protein 2B
chr10_-_36812323 0.14 ENST00000543053.1
nicotinamide phosphoribosyltransferase-like
chr20_-_52612705 0.14 ENST00000434986.2
breast carcinoma amplified sequence 1
chr10_+_17272608 0.13 ENST00000421459.2
vimentin
chr11_+_86748998 0.13 ENST00000525018.1
ENST00000355734.4
transmembrane protein 135
chr7_-_93520191 0.13 ENST00000545378.1
tissue factor pathway inhibitor 2
chr3_+_101280677 0.13 ENST00000309922.6
ENST00000495642.1
tRNA methyltransferase 10 homolog C (S. cerevisiae)
chr3_+_122044084 0.13 ENST00000264474.3
ENST00000479204.1
cystatin A (stefin A)
chr10_-_91403625 0.13 ENST00000322191.6
ENST00000342512.3
ENST00000371774.2
pantothenate kinase 1
chr12_+_12878829 0.13 ENST00000326765.6
apolipoprotein L domain containing 1
chr17_-_8113542 0.13 ENST00000578549.1
ENST00000535053.1
ENST00000582368.1
aurora kinase B
chr11_-_61101247 0.13 ENST00000543627.1
damage-specific DNA binding protein 1, 127kDa
chr3_-_111852061 0.13 ENST00000488580.1
ENST00000460387.2
ENST00000484193.1
ENST00000487901.1
germinal center-associated, signaling and motility
chr1_+_155583012 0.13 ENST00000462250.2
misato 1, mitochondrial distribution and morphology regulator
chr20_+_30327063 0.13 ENST00000300403.6
ENST00000340513.4
TPX2, microtubule-associated
chr10_-_70092671 0.13 ENST00000358769.2
ENST00000432941.1
ENST00000495025.2
phenazine biosynthesis-like protein domain containing
chr7_-_102789629 0.13 ENST00000417955.1
ENST00000341533.4
ENST00000425379.1
N-acyl phosphatidylethanolamine phospholipase D
chr2_-_61244550 0.13 ENST00000421319.1
pseudouridylate synthase 10
chr11_-_33774944 0.12 ENST00000532057.1
ENST00000531080.1
F-box protein 3
chr8_-_63998590 0.12 ENST00000260116.4
tocopherol (alpha) transfer protein
chr12_+_12510045 0.12 ENST00000314565.4
loss of heterozygosity, 12, chromosomal region 1
chr19_-_43422019 0.12 ENST00000402603.4
ENST00000594375.1
pregnancy specific beta-1-glycoprotein 6
chr8_+_7705398 0.12 ENST00000400125.2
ENST00000434307.2
ENST00000326558.5
ENST00000351436.4
ENST00000528033.1
sperm associated antigen 11A
chr1_-_169337176 0.12 ENST00000472647.1
ENST00000367811.3
NME/NM23 family member 7
chr18_+_3247779 0.12 ENST00000578611.1
ENST00000583449.1
myosin, light chain 12A, regulatory, non-sarcomeric
chr12_+_69753448 0.12 ENST00000247843.2
ENST00000548020.1
ENST00000549685.1
ENST00000552955.1
YEATS domain containing 4
chr8_-_7320974 0.12 ENST00000528943.1
ENST00000359758.5
ENST00000361111.2
ENST00000398462.2
ENST00000297498.2
ENST00000317900.5
sperm associated antigen 11B
chr4_-_75695366 0.12 ENST00000512743.1
betacellulin
chr1_+_42928945 0.12 ENST00000428554.2
coiled-coil domain containing 30
chr14_+_39734482 0.12 ENST00000554392.1
ENST00000555716.1
ENST00000341749.3
ENST00000557038.1
CTAGE family, member 5
chr7_-_2349579 0.12 ENST00000435060.1
sorting nexin 8
chr13_-_46716969 0.12 ENST00000435666.2
lymphocyte cytosolic protein 1 (L-plastin)
chr5_+_154238149 0.12 ENST00000519430.1
ENST00000520671.1
ENST00000521583.1
ENST00000518028.1
ENST00000519404.1
ENST00000519394.1
ENST00000518775.1
CCR4-NOT transcription complex, subunit 8
chr3_-_187455680 0.12 ENST00000438077.1
B-cell CLL/lymphoma 6
chr12_+_62860581 0.12 ENST00000393632.2
ENST00000393630.3
ENST00000280379.6
ENST00000546600.1
ENST00000552738.1
ENST00000393629.2
ENST00000552115.1
MON2 homolog (S. cerevisiae)
chr12_-_88535747 0.11 ENST00000309041.7
centrosomal protein 290kDa
chr20_+_814377 0.11 ENST00000304189.2
ENST00000381939.1
family with sequence similarity 110, member A
chr1_-_10532531 0.11 ENST00000377036.2
ENST00000377038.3
DNA fragmentation factor, 45kDa, alpha polypeptide
chr17_+_30469579 0.11 ENST00000354266.3
ENST00000581094.1
ENST00000394692.2
ras homolog family member T1
chr4_+_52917451 0.11 ENST00000295213.4
ENST00000419395.2
spermatogenesis associated 18
chrX_-_48693955 0.11 ENST00000218230.5
proprotein convertase subtilisin/kexin type 1 inhibitor
chr1_-_94344754 0.11 ENST00000436063.2
deoxynucleotidyltransferase, terminal, interacting protein 2
chr13_+_25875662 0.11 ENST00000381736.3
ENST00000463407.1
ENST00000381718.3
nucleoporin like 1
chr1_-_85358850 0.11 ENST00000370611.3
lysophosphatidic acid receptor 3
chr4_-_106629796 0.11 ENST00000416543.1
ENST00000515819.1
ENST00000420368.2
ENST00000503746.1
ENST00000340139.5
ENST00000433009.1
integrator complex subunit 12
chr11_+_124824000 0.11 ENST00000529051.1
ENST00000344762.5
coiled-coil domain containing 15
chr18_+_21033239 0.11 ENST00000581585.1
ENST00000577501.1
RIO kinase 3
chr4_+_113558272 0.11 ENST00000509061.1
ENST00000508577.1
ENST00000513553.1
La ribonucleoprotein domain family, member 7
chr10_+_105881906 0.10 ENST00000369727.3
ENST00000336358.5
SWI5-dependent recombination repair 1
chr15_+_41186637 0.10 ENST00000558474.1
vacuolar protein sorting 18 homolog (S. cerevisiae)
chr3_-_57678772 0.10 ENST00000311128.5
DENN/MADD domain containing 6A
chr19_+_44716768 0.10 ENST00000586048.1
zinc finger protein 227
chr5_+_134240588 0.10 ENST00000254908.6
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
chr9_-_6015607 0.10 ENST00000259569.5
RAN binding protein 6
chr7_+_138818490 0.10 ENST00000430935.1
ENST00000495038.1
ENST00000474035.2
ENST00000478836.2
ENST00000464848.1
ENST00000343187.4
tetratricopeptide repeat domain 26
chr12_-_46121554 0.10 ENST00000609803.1
long intergenic non-protein coding RNA 938
chr18_-_59274139 0.10 ENST00000586949.1
RP11-879F14.2
chrX_-_153979315 0.10 ENST00000369575.3
ENST00000369568.4
ENST00000424127.2
GRB2-associated binding protein 3
chr4_+_187148556 0.10 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
kallikrein B, plasma (Fletcher factor) 1
chr6_+_73331520 0.10 ENST00000342056.2
ENST00000355194.4
potassium voltage-gated channel, KQT-like subfamily, member 5
chr3_-_57233966 0.10 ENST00000473921.1
ENST00000295934.3
HESX homeobox 1
chr12_-_48597170 0.10 ENST00000310248.2
olfactory receptor, family 10, subfamily AD, member 1
chr1_+_28052456 0.10 ENST00000373954.6
ENST00000419687.2
family with sequence similarity 76, member A
chr6_+_53976235 0.10 ENST00000502396.1
ENST00000358276.5
muscular LMNA-interacting protein
chr20_+_9049303 0.10 ENST00000407043.2
ENST00000441846.1
phospholipase C, beta 4
chr2_+_46926048 0.10 ENST00000306503.5
suppressor of cytokine signaling 5
chr13_-_41706864 0.10 ENST00000379485.1
ENST00000499385.2
kelch repeat and BTB (POZ) domain containing 6
chr12_+_123459127 0.10 ENST00000397389.2
ENST00000538755.1
ENST00000536150.1
ENST00000545056.1
ENST00000545612.1
ENST00000538628.1
ENST00000545317.1
2-oxoglutarate and iron-dependent oxygenase domain containing 2
chr4_-_113558014 0.10 ENST00000503172.1
ENST00000505019.1
ENST00000309071.5
chromosome 4 open reading frame 21
chr15_-_85197501 0.10 ENST00000434634.2
WD repeat domain 73
chr1_-_111991850 0.10 ENST00000411751.2
WD repeat domain 77
chr11_+_112047087 0.10 ENST00000526088.1
ENST00000532593.1
ENST00000531169.1
beta-carotene oxygenase 2
chr2_+_73114489 0.10 ENST00000234454.5
sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
chr2_+_109335929 0.10 ENST00000283195.6
RAN binding protein 2
chr7_-_95025661 0.10 ENST00000542556.1
ENST00000265627.5
ENST00000427422.1
ENST00000451904.1
paraoxonase 1
paraoxonase 3
chr3_-_146262428 0.10 ENST00000486631.1
phospholipid scramblase 1
chr15_+_74919779 0.09 ENST00000566926.1
CDC-like kinase 3
chr1_+_209859510 0.09 ENST00000367028.2
ENST00000261465.1
hydroxysteroid (11-beta) dehydrogenase 1
chr9_+_131901661 0.09 ENST00000423100.1
protein phosphatase 2A activator, regulatory subunit 4
chr2_+_196522032 0.09 ENST00000418005.1
solute carrier family 39 (zinc transporter), member 10
chr9_-_130889990 0.09 ENST00000449878.1
prostaglandin E synthase 2
chr14_-_31926623 0.09 ENST00000356180.4
D-tyrosyl-tRNA deacylase 2 (putative)
chr19_+_58193337 0.09 ENST00000601064.1
ENST00000282296.5
ENST00000356715.4
zinc finger protein 551
chr9_+_96793076 0.09 ENST00000375360.3
protein tyrosine phosphatase domain containing 1
chr17_-_5487768 0.09 ENST00000269280.4
ENST00000345221.3
ENST00000262467.5
NLR family, pyrin domain containing 1
chr5_-_156569850 0.09 ENST00000524219.1
hepatitis A virus cellular receptor 2
chr12_+_121647868 0.09 ENST00000359949.7
ENST00000541532.1
ENST00000543171.1
ENST00000538701.1
purinergic receptor P2X, ligand-gated ion channel, 4
chr4_-_169931393 0.09 ENST00000504480.1
ENST00000306193.3
carbonyl reductase 4
chr1_-_118727781 0.09 ENST00000336338.5
sperm associated antigen 17

Network of associatons between targets according to the STRING database.

First level regulatory network of HSFY2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.3 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.2 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.1 0.2 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
0.1 0.2 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 0.2 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.2 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.2 GO:2000685 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.2 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.0 0.3 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.0 0.2 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.2 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.2 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.4 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.3 GO:0009820 alkaloid metabolic process(GO:0009820)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.2 GO:1903998 response to isolation stress(GO:0035900) regulation of eating behavior(GO:1903998) negative regulation of feeding behavior(GO:2000252)
0.0 0.2 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.0 0.7 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.1 GO:0002519 natural killer cell tolerance induction(GO:0002519) regulation of tolerance induction dependent upon immune response(GO:0002652) negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859)
0.0 0.1 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.0 0.2 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:1904468 negative regulation of tumor necrosis factor secretion(GO:1904468) calcium ion regulated lysosome exocytosis(GO:1990927)
0.0 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:0072434 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.1 GO:0090210 vitamin E metabolic process(GO:0042360) regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.0 0.4 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 0.1 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.1 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.1 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.0 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.2 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.1 GO:0060127 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.0 0.1 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.1 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.0 0.1 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.1 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.2 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
0.0 0.2 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.0 0.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.0 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.0 GO:0050904 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) diapedesis(GO:0050904)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.0 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.0 GO:0060057 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.0 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.2 GO:0015827 tryptophan transport(GO:0015827)
0.0 0.0 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:0007059 chromosome segregation(GO:0007059)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 0.1 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.0 0.0 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.1 GO:0010710 regulation of collagen catabolic process(GO:0010710)
0.0 0.1 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.4 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.0 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.0 0.1 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.3 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.1 0.2 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.3 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.2 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.1 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.0 0.1 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 0.3 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.0 0.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.3 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0070685 macropinocytic cup(GO:0070685)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.0 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.0 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.0 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.0 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.2 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 0.2 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.1 0.7 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.3 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.1 0.3 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.2 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.2 GO:0035501 MH1 domain binding(GO:0035501)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.1 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0008124 phenylalanine 4-monooxygenase activity(GO:0004505) 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.0 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.3 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.1 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.1 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.1 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.6 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.0 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.0 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.0 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.0 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.0 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.3 GO:0070330 aromatase activity(GO:0070330)
0.0 0.3 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.0 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.2 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.1 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.2 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.9 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin