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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXC9

Z-value: 1.05

Motif logo

Transcription factors associated with HOXC9

Gene Symbol Gene ID Gene Info
ENSG00000180806.4 homeobox C9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXC9hg19_v2_chr12_+_54393880_54393962-0.315.5e-01Click!

Activity profile of HOXC9 motif

Sorted Z-values of HOXC9 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_71104588 1.18 ENST00000418403.1
RP11-462G2.1
chr12_+_25348186 1.01 ENST00000555711.1
ENST00000556885.1
ENST00000554266.1
ENST00000556351.1
ENST00000556927.1
ENST00000556402.1
ENST00000553788.1
LYR motif containing 5
chr18_+_44812072 0.98 ENST00000598649.1
ENST00000586905.2
CTD-2130O13.1
chr9_-_95055923 0.83 ENST00000430417.1
isoleucyl-tRNA synthetase
chr6_-_52859046 0.78 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
glutathione S-transferase alpha 4
chr6_-_26189304 0.75 ENST00000340756.2
histone cluster 1, H4d
chr17_+_58018269 0.74 ENST00000591035.1
Uncharacterized protein
chr12_+_25348139 0.68 ENST00000557540.2
ENST00000381356.4
LYR motif containing 5
chr12_+_104235229 0.66 ENST00000551650.1
Uncharacterized protein
chr22_+_22676808 0.64 ENST00000390290.2
immunoglobulin lambda variable 1-51
chr6_-_52859968 0.58 ENST00000370959.1
glutathione S-transferase alpha 4
chr17_+_67498396 0.56 ENST00000588110.1
mitogen-activated protein kinase kinase 6
chr16_-_66907139 0.55 ENST00000561579.2
NEDD8 activating enzyme E1 subunit 1
chr5_-_42811986 0.52 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chr12_-_104234966 0.51 ENST00000392876.3
5'-nucleotidase domain containing 3
chr9_-_15472730 0.49 ENST00000481862.1
PC4 and SFRS1 interacting protein 1
chrX_+_150565038 0.48 ENST00000370361.1
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr12_+_25205155 0.48 ENST00000550945.1
lymphoid-restricted membrane protein
chr1_-_197115818 0.48 ENST00000367409.4
ENST00000294732.7
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr11_-_26593779 0.48 ENST00000529533.1
mucin 15, cell surface associated
chr14_+_39944025 0.47 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
chr5_-_42812143 0.45 ENST00000514985.1
selenoprotein P, plasma, 1
chr8_-_81083890 0.45 ENST00000518937.1
tumor protein D52
chr12_+_25205446 0.45 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
lymphoid-restricted membrane protein
chr11_-_14521349 0.44 ENST00000534234.1
coatomer protein complex, subunit beta 1
chr4_-_70626430 0.42 ENST00000310613.3
sulfotransferase family, cytosolic, 1B, member 1
chr2_+_160590469 0.41 ENST00000409591.1
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
chr16_+_67552303 0.41 ENST00000562116.1
family with sequence similarity 65, member A
chr12_+_25205568 0.40 ENST00000548766.1
ENST00000556887.1
lymphoid-restricted membrane protein
chr9_-_75488984 0.40 ENST00000423171.1
ENST00000449235.1
ENST00000453787.1
RP11-151D14.1
chr8_-_17555164 0.40 ENST00000297488.6
microtubule associated tumor suppressor 1
chr22_+_45714361 0.39 ENST00000452238.1
family with sequence similarity 118, member A
chr1_+_63989004 0.38 ENST00000371088.4
EF-hand calcium binding domain 7
chr1_+_152784447 0.38 ENST00000360090.3
late cornified envelope 1B
chr6_-_121655850 0.37 ENST00000422369.1
TBC1 domain family, member 32
chr16_-_66764119 0.37 ENST00000569320.1
dynein, cytoplasmic 1, light intermediate chain 2
chr19_+_21264943 0.37 ENST00000597424.1
zinc finger protein 714
chr11_-_111649074 0.37 ENST00000534218.1
RP11-108O10.2
chr3_-_170587815 0.36 ENST00000466674.1
ribosomal protein L22-like 1
chr8_-_93978309 0.36 ENST00000517858.1
ENST00000378861.5
triple QxxK/R motif containing
chr10_-_96829246 0.36 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
cytochrome P450, family 2, subfamily C, polypeptide 8
chr19_+_21106081 0.36 ENST00000300540.3
ENST00000595854.1
ENST00000601284.1
ENST00000328178.8
ENST00000599885.1
ENST00000596476.1
ENST00000345030.6
zinc finger protein 85
chr3_-_170587974 0.35 ENST00000463836.1
ribosomal protein L22-like 1
chr7_+_138915102 0.35 ENST00000486663.1
ubinuclein 2
chr1_+_32379174 0.33 ENST00000391369.1
HCG2032337; PRO1848; Uncharacterized protein
chr13_+_108921977 0.32 ENST00000430559.1
ENST00000375887.4
tumor necrosis factor (ligand) superfamily, member 13b
chr3_+_87276407 0.32 ENST00000471660.1
ENST00000263780.4
ENST00000494980.1
charged multivesicular body protein 2B
chr8_+_104033296 0.32 ENST00000521514.1
ENST00000518738.1
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
chr17_+_61151306 0.32 ENST00000580068.1
ENST00000580466.1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr2_-_17981462 0.32 ENST00000402989.1
ENST00000428868.1
structural maintenance of chromosomes 6
chr8_-_17579726 0.31 ENST00000381861.3
microtubule associated tumor suppressor 1
chr8_-_71157595 0.31 ENST00000519724.1
nuclear receptor coactivator 2
chr4_+_71600063 0.31 ENST00000513597.1
RUN and FYVE domain containing 3
chr1_-_113615699 0.30 ENST00000421157.1
RP11-31F15.2
chrX_+_13671225 0.30 ENST00000545566.1
ENST00000544987.1
ENST00000314720.4
transcription elongation factor A (SII) N-terminal and central domain containing
chr6_-_109702885 0.30 ENST00000504373.1
CD164 molecule, sialomucin
chr2_-_160568529 0.29 ENST00000418770.1
AC009961.3
chr3_-_170588163 0.29 ENST00000295830.8
ribosomal protein L22-like 1
chr2_+_109204909 0.29 ENST00000393310.1
LIM and senescent cell antigen-like domains 1
chr2_+_162016827 0.29 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TRAF family member-associated NFKB activator
chr3_+_56591184 0.29 ENST00000422222.1
ENST00000394672.3
ENST00000326595.7
coiled-coil domain containing 66
chr14_+_60712463 0.28 ENST00000325642.3
ENST00000529574.1
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr20_+_5987890 0.28 ENST00000378868.4
cardiolipin synthase 1
chr10_+_98592009 0.27 ENST00000540664.1
ENST00000371103.3
ligand dependent nuclear receptor corepressor
chrX_+_105937068 0.27 ENST00000324342.3
ring finger protein 128, E3 ubiquitin protein ligase
chr19_+_21264980 0.27 ENST00000596053.1
ENST00000597086.1
ENST00000596143.1
ENST00000596367.1
ENST00000601416.1
zinc finger protein 714
chr1_-_204183071 0.27 ENST00000308302.3
golgi transport 1A
chr7_+_130126165 0.26 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
mesoderm specific transcript
chr8_+_92114060 0.26 ENST00000518304.1
leucine rich repeat containing 69
chrX_+_123097014 0.26 ENST00000394478.1
stromal antigen 2
chr5_-_139930713 0.26 ENST00000602657.1
steroid receptor RNA activator 1
chr12_+_19358228 0.25 ENST00000424268.1
ENST00000543806.1
pleckstrin homology domain containing, family A member 5
chr14_+_57671888 0.25 ENST00000391612.1
AL391152.1
chr17_+_48823975 0.25 ENST00000513969.1
ENST00000503728.1
LUC7-like 3 (S. cerevisiae)
chr7_+_64838712 0.25 ENST00000328747.7
ENST00000431504.1
ENST00000357512.2
zinc finger protein 92
chr8_-_82608409 0.25 ENST00000518568.1
solute carrier family 10, member 5
chr16_+_58074069 0.24 ENST00000570065.1
matrix metallopeptidase 15 (membrane-inserted)
chr11_+_65266507 0.24 ENST00000544868.1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr10_+_5238793 0.24 ENST00000263126.1
aldo-keto reductase family 1, member C4
chr2_-_109605663 0.24 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
ectodysplasin A receptor
chr3_+_143690640 0.24 ENST00000315691.3
chromosome 3 open reading frame 58
chr19_-_23869999 0.24 ENST00000601935.1
ENST00000359788.4
ENST00000600313.1
ENST00000596211.1
ENST00000599168.1
zinc finger protein 675
chr7_+_7196565 0.23 ENST00000429911.1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr8_-_42396185 0.23 ENST00000518717.1
solute carrier family 20 (phosphate transporter), member 2
chr7_+_64838786 0.23 ENST00000450302.2
zinc finger protein 92
chr8_+_104033277 0.23 ENST00000518857.1
ENST00000395862.3
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
chr8_-_93978216 0.22 ENST00000517751.1
ENST00000524107.1
triple QxxK/R motif containing
chr11_-_26593677 0.22 ENST00000527569.1
mucin 15, cell surface associated
chr6_-_111804905 0.21 ENST00000358835.3
ENST00000435970.1
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr1_+_233086326 0.21 ENST00000366628.5
ENST00000366627.4
nucleoside-triphosphatase, cancer-related
chr2_-_134326009 0.21 ENST00000409261.1
ENST00000409213.1
NCK-associated protein 5
chr2_+_161993465 0.21 ENST00000457476.1
TRAF family member-associated NFKB activator
chr2_-_8723918 0.21 ENST00000454224.1
AC011747.4
chr8_-_80993010 0.21 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
tumor protein D52
chr13_-_30424821 0.20 ENST00000380680.4
ubiquitin-like 3
chr8_-_93978333 0.20 ENST00000524037.1
ENST00000520430.1
ENST00000521617.1
triple QxxK/R motif containing
chr11_+_19798964 0.20 ENST00000527559.2
neuron navigator 2
chr18_+_32558380 0.20 ENST00000588349.2
microtubule-associated protein, RP/EB family, member 2
chr18_+_20378191 0.20 ENST00000583700.1
retinoblastoma binding protein 8
chr2_+_38177575 0.20 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
regulator of microtubule dynamics 2
chr14_+_55494323 0.20 ENST00000339298.2
suppressor of cytokine signaling 4
chr5_-_111093167 0.20 ENST00000446294.2
ENST00000419114.2
neuronal regeneration related protein
chr12_-_63328817 0.20 ENST00000228705.6
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr18_-_32870148 0.19 ENST00000589178.1
ENST00000333206.5
ENST00000592278.1
ENST00000592211.1
ENST00000420878.3
ENST00000383091.2
ENST00000586922.2
zinc finger and SCAN domain containing 30
RP11-158H5.7
chr16_-_48281305 0.19 ENST00000356608.2
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr12_-_110906027 0.19 ENST00000537466.2
ENST00000550974.1
ENST00000228827.3
GPN-loop GTPase 3
chr15_+_45003675 0.19 ENST00000558401.1
ENST00000559916.1
ENST00000544417.1
beta-2-microglobulin
chr3_+_69812701 0.19 ENST00000472437.1
microphthalmia-associated transcription factor
chr2_+_172309634 0.19 ENST00000339506.3
DDB1 and CUL4 associated factor 17
chr4_-_103749105 0.19 ENST00000394801.4
ENST00000394804.2
ubiquitin-conjugating enzyme E2D 3
chr10_-_113943447 0.19 ENST00000369425.1
ENST00000348367.4
ENST00000423155.1
glycerol-3-phosphate acyltransferase, mitochondrial
chr15_+_40987327 0.19 ENST00000423169.2
ENST00000267868.3
ENST00000557850.1
ENST00000532743.1
ENST00000382643.3
RAD51 recombinase
chr4_-_100065440 0.19 ENST00000508393.1
ENST00000265512.7
alcohol dehydrogenase 4 (class II), pi polypeptide
chr19_+_9296279 0.18 ENST00000344248.2
olfactory receptor, family 7, subfamily D, member 2
chr8_-_18711866 0.18 ENST00000519851.1
pleckstrin and Sec7 domain containing 3
chr5_+_136070614 0.18 ENST00000502421.1
CTB-1I21.1
chr4_+_86525299 0.18 ENST00000512201.1
Rho GTPase activating protein 24
chr4_+_106631966 0.18 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
glutathione S-transferase, C-terminal domain containing
chr16_+_53412368 0.18 ENST00000565189.1
RP11-44F14.2
chr8_-_81083731 0.17 ENST00000379096.5
tumor protein D52
chr8_+_52730143 0.17 ENST00000415643.1
Uncharacterized protein
chr2_+_196440692 0.17 ENST00000458054.1
solute carrier family 39 (zinc transporter), member 10
chr8_-_93978357 0.17 ENST00000522925.1
ENST00000522903.1
ENST00000537541.1
ENST00000518748.1
ENST00000519069.1
ENST00000521988.1
triple QxxK/R motif containing
chr14_+_31046959 0.17 ENST00000547532.1
ENST00000555429.1
G2/M-phase specific E3 ubiquitin protein ligase
chr13_-_36050819 0.17 ENST00000379919.4
mab-21-like 1 (C. elegans)
chr3_-_47023455 0.16 ENST00000446836.1
ENST00000425441.1
coiled-coil domain containing 12
chr11_+_114310164 0.16 ENST00000544196.1
ENST00000539754.1
ENST00000539275.1
RNA exonuclease 2
chr9_+_2029019 0.16 ENST00000382194.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_+_210443993 0.16 ENST00000392193.1
microtubule-associated protein 2
chr2_+_210444298 0.16 ENST00000445941.1
microtubule-associated protein 2
chr3_-_25824872 0.16 ENST00000308710.5
N-glycanase 1
chr1_-_147599549 0.16 ENST00000369228.5
neuroblastoma breakpoint family, member 24
chr3_+_113251143 0.16 ENST00000264852.4
ENST00000393830.3
SID1 transmembrane family, member 1
chr2_+_109271481 0.16 ENST00000542845.1
ENST00000393314.2
LIM and senescent cell antigen-like domains 1
chr19_-_20748541 0.16 ENST00000427401.4
ENST00000594419.1
zinc finger protein 737
chr12_-_15815626 0.15 ENST00000540613.1
epidermal growth factor receptor pathway substrate 8
chr16_-_56485257 0.15 ENST00000300291.5
nudix (nucleoside diphosphate linked moiety X)-type motif 21
chrX_+_105936982 0.15 ENST00000418562.1
ring finger protein 128, E3 ubiquitin protein ligase
chrX_+_41193407 0.15 ENST00000457138.2
ENST00000441189.2
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr2_+_219472488 0.15 ENST00000450993.2
phospholipase C, delta 4
chr10_-_128110441 0.15 ENST00000456514.1
long intergenic non-protein coding RNA 601
chr6_-_146057144 0.15 ENST00000367519.3
epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
chr7_+_130126012 0.15 ENST00000341441.5
mesoderm specific transcript
chr22_-_24126145 0.15 ENST00000598975.1
Uncharacterized protein
chr3_+_41241596 0.14 ENST00000450969.1
catenin (cadherin-associated protein), beta 1, 88kDa
chr19_+_21265028 0.14 ENST00000291770.7
zinc finger protein 714
chr12_+_19358192 0.14 ENST00000538305.1
pleckstrin homology domain containing, family A member 5
chr1_-_212965104 0.14 ENST00000422588.2
ENST00000366975.6
ENST00000366977.3
ENST00000366976.1
NSL1, MIS12 kinetochore complex component
chr11_-_104972158 0.14 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr16_+_71560023 0.14 ENST00000572450.1
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr18_-_74839891 0.14 ENST00000581878.1
myelin basic protein
chr2_+_128458514 0.14 ENST00000310981.4
SFT2 domain containing 3
chr2_-_200320768 0.14 ENST00000428695.1
SATB homeobox 2
chr17_+_44803922 0.14 ENST00000465370.1
N-ethylmaleimide-sensitive factor
chr2_+_162016916 0.14 ENST00000405852.1
TRAF family member-associated NFKB activator
chr9_+_80912059 0.14 ENST00000347159.2
ENST00000376588.3
phosphoserine aminotransferase 1
chr9_-_98189055 0.14 ENST00000433644.2
RP11-435O5.2
chr12_+_25205628 0.14 ENST00000554942.1
lymphoid-restricted membrane protein
chrX_-_13835147 0.14 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chrX_-_13321511 0.14 ENST00000412485.1
ENST00000443965.1
GS1-600G8.5
chr5_+_169011033 0.13 ENST00000513795.1
spindle apparatus coiled-coil protein 1
chr10_+_76871353 0.13 ENST00000542569.1
sterile alpha motif domain containing 8
chr3_+_69811858 0.13 ENST00000433517.1
microphthalmia-associated transcription factor
chr5_-_159846066 0.13 ENST00000519349.1
ENST00000520664.1
SLU7 splicing factor homolog (S. cerevisiae)
chr3_+_112709804 0.13 ENST00000383677.3
GTP-binding protein 8 (putative)
chr20_-_36152914 0.13 ENST00000397131.1
bladder cancer associated protein
chr12_-_8803128 0.13 ENST00000543467.1
microfibrillar associated protein 5
chr22_+_21133469 0.13 ENST00000406799.1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr2_-_86850949 0.13 ENST00000237455.4
ring finger protein 103
chr18_+_29027696 0.12 ENST00000257189.4
desmoglein 3
chr2_+_187371440 0.12 ENST00000445547.1
zinc finger CCCH-type containing 15
chr1_+_87012922 0.12 ENST00000263723.5
chloride channel accessory 4
chr13_+_49551020 0.12 ENST00000541916.1
fibronectin type III domain containing 3A
chr5_-_145562147 0.12 ENST00000545646.1
ENST00000274562.9
ENST00000510191.1
ENST00000394434.2
leucyl-tRNA synthetase
chr10_-_13344341 0.12 ENST00000396920.3
phytanoyl-CoA 2-hydroxylase
chr1_-_157069590 0.12 ENST00000454449.2
ets variant 3-like
chr8_-_116504448 0.12 ENST00000518018.1
trichorhinophalangeal syndrome I
chr1_+_150039877 0.12 ENST00000419023.1
vacuolar protein sorting 45 homolog (S. cerevisiae)
chr16_+_68119764 0.12 ENST00000570212.1
ENST00000562926.1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr6_+_111303218 0.12 ENST00000441448.2
ribosome production factor 2 homolog (S. cerevisiae)
chr7_+_102937869 0.12 ENST00000249269.4
ENST00000428154.1
ENST00000420236.2
peptidase (mitochondrial processing) beta
chr2_+_207630081 0.11 ENST00000236980.6
ENST00000418289.1
ENST00000402774.3
ENST00000403094.3
FAST kinase domains 2
chr2_+_109237717 0.11 ENST00000409441.1
LIM and senescent cell antigen-like domains 1
chr3_+_111630451 0.11 ENST00000495180.1
pleckstrin homology-like domain, family B, member 2
chr8_-_93978346 0.11 ENST00000523580.1
triple QxxK/R motif containing
chr7_+_93690435 0.11 ENST00000438538.1
AC003092.1
chr8_+_132916318 0.11 ENST00000254624.5
ENST00000522709.1
EFR3 homolog A (S. cerevisiae)
chr2_+_158114051 0.11 ENST00000259056.4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr17_-_28257080 0.11 ENST00000579954.1
ENST00000540801.1
ENST00000269033.3
ENST00000590153.1
ENST00000582084.1
slingshot protein phosphatase 2
chr10_+_115614370 0.11 ENST00000369301.3
NHL repeat containing 2
chrX_-_131353461 0.11 ENST00000370874.1
RAP2C, member of RAS oncogene family
chr22_-_32766972 0.11 ENST00000382084.4
ENST00000382086.2
RFPL3 antisense
chr17_-_42767092 0.11 ENST00000588687.1
coiled-coil domain containing 43
chr8_-_101718991 0.11 ENST00000517990.1
poly(A) binding protein, cytoplasmic 1
chr4_-_103748880 0.10 ENST00000453744.2
ENST00000349311.8
ubiquitin-conjugating enzyme E2D 3
chr9_-_20382446 0.10 ENST00000380321.1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr1_+_163039143 0.10 ENST00000531057.1
ENST00000527809.1
ENST00000367908.4
regulator of G-protein signaling 4
chr17_+_76494911 0.10 ENST00000598378.1
DNAH17 antisense RNA 1
chrX_+_120181457 0.10 ENST00000328078.1
glutamate dehydrogenase 2
chr2_-_122262593 0.10 ENST00000418989.1
cytoplasmic linker associated protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.2 0.5 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.5 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.3 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.8 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.3 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.1 0.3 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.1 0.2 GO:1903989 positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.1 0.2 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.1 0.2 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 0.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.4 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.2 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.2 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0006429 glutaminyl-tRNA aminoacylation(GO:0006425) leucyl-tRNA aminoacylation(GO:0006429)
0.0 0.4 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 1.4 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.1 GO:1904501 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.0 0.3 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.3 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.2 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.2 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.2 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.4 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.1 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.1 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.2 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.1 GO:0035633 maintenance of blood-brain barrier(GO:0035633) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0042816 vitamin B6 metabolic process(GO:0042816)
0.0 0.3 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.0 0.1 GO:2000525 negative regulation of regulatory T cell differentiation(GO:0045590) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.2 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.3 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.4 GO:0007498 mesoderm development(GO:0007498)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 0.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.4 GO:0002643 regulation of tolerance induction(GO:0002643)
0.0 0.5 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.2 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.3 GO:0009886 post-embryonic morphogenesis(GO:0009886)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.0 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.1 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.6 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 0.2 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.0 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.0 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.1 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 1.6 GO:0007338 single fertilization(GO:0007338)
0.0 0.6 GO:0006958 complement activation, classical pathway(GO:0006958)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 0.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.5 GO:0072687 meiotic spindle(GO:0072687)
0.0 1.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.3 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.2 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.1 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.1 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0070369 Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 1.4 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.2 0.5 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 0.8 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.3 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.1 0.4 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1 0.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.3 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.2 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.1 0.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.2 GO:0000224 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity(GO:0000224)
0.0 0.2 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.1 GO:0004823 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.0 0.1 GO:0048244 phytanoyl-CoA dioxygenase activity(GO:0048244)
0.0 0.5 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 1.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.2 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.0 0.1 GO:0019115 benzaldehyde dehydrogenase activity(GO:0019115)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.0 0.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.2 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.1 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 0.0 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.4 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10