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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXB8

Z-value: 0.57

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Transcription factors associated with HOXB8

Gene Symbol Gene ID Gene Info
HOXB8
ENSG00000120068.5 homeobox B8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB8hg19_v2_chr17_-_46691990_466920660.572.3e-01Click!

Activity profile of HOXB8 motif

Sorted Z-values of HOXB8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_93692681 0.40 ENST00000348974.4
PROS1
protein S (alpha)
chr4_-_118006697 0.39 ENST00000310754.4
TRAM1L1
translocation associated membrane protein 1-like 1
chr7_+_23637763 0.39 ENST00000410069.1
CCDC126
coiled-coil domain containing 126
chr7_+_135777671 0.36 ENST00000445293.2
ENST00000435996.1
AC009784.3
AC009784.3
chrX_+_3189861 0.35 ENST00000457435.1
ENST00000420429.2
CXorf28
chromosome X open reading frame 28
chr20_+_58571419 0.33 ENST00000244049.3
ENST00000350849.6
ENST00000456106.1
CDH26
cadherin 26
chr1_-_67142710 0.32 ENST00000502413.2
AL139147.1
Uncharacterized protein
chr12_-_10601963 0.31 ENST00000543893.1
KLRC1
killer cell lectin-like receptor subfamily C, member 1
chr11_-_14521349 0.31 ENST00000534234.1
COPB1
coatomer protein complex, subunit beta 1
chr1_-_63988846 0.30 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
ITGB3BP
integrin beta 3 binding protein (beta3-endonexin)
chr9_-_75488984 0.30 ENST00000423171.1
ENST00000449235.1
ENST00000453787.1
RP11-151D14.1
RP11-151D14.1
chr12_-_22063787 0.29 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr4_-_112993808 0.28 ENST00000511219.1
RP11-269F21.3
RP11-269F21.3
chr3_-_55539287 0.27 ENST00000472238.1
RP11-875H7.5
RP11-875H7.5
chr4_-_89442940 0.27 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr12_+_51317788 0.27 ENST00000550502.1
METTL7A
methyltransferase like 7A
chr15_-_83224682 0.26 ENST00000562833.1
RP11-152F13.10
RP11-152F13.10
chr1_+_224544572 0.25 ENST00000366857.5
ENST00000366856.3
CNIH4
cornichon family AMPA receptor auxiliary protein 4
chr1_+_87012922 0.25 ENST00000263723.5
CLCA4
chloride channel accessory 4
chr9_-_15472730 0.25 ENST00000481862.1
PSIP1
PC4 and SFRS1 interacting protein 1
chr6_+_63921351 0.25 ENST00000370659.1
FKBP1C
FK506 binding protein 1C
chr2_-_188312971 0.25 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
CALCRL
calcitonin receptor-like
chr1_+_154378049 0.24 ENST00000512471.1
IL6R
interleukin 6 receptor
chr15_+_49715449 0.24 ENST00000560979.1
FGF7
fibroblast growth factor 7
chr12_+_25205155 0.24 ENST00000550945.1
LRMP
lymphoid-restricted membrane protein
chr5_-_42825983 0.22 ENST00000506577.1
SEPP1
selenoprotein P, plasma, 1
chr12_+_25205568 0.22 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr7_-_77325545 0.22 ENST00000447009.1
ENST00000416650.1
ENST00000440088.1
ENST00000430801.1
ENST00000398043.2
RSBN1L-AS1
RSBN1L antisense RNA 1
chr5_-_132362226 0.22 ENST00000509437.1
ENST00000355372.2
ENST00000513541.1
ENST00000509008.1
ENST00000513848.1
ENST00000504170.1
ENST00000324170.3
ZCCHC10
zinc finger, CCHC domain containing 10
chr5_+_147691979 0.22 ENST00000274565.4
SPINK7
serine peptidase inhibitor, Kazal type 7 (putative)
chr17_+_67498396 0.21 ENST00000588110.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr4_+_83956237 0.21 ENST00000264389.2
COPS4
COP9 signalosome subunit 4
chr17_-_41050716 0.21 ENST00000417193.1
ENST00000301683.3
ENST00000436546.1
ENST00000431109.2
LINC00671
long intergenic non-protein coding RNA 671
chr14_-_71107921 0.21 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
CTD-2540L5.5
CTD-2540L5.6
chr5_+_59726565 0.20 ENST00000412930.2
FKSG52
FKSG52
chr4_+_48833312 0.20 ENST00000508293.1
ENST00000513391.2
OCIAD1
OCIA domain containing 1
chr2_+_29353520 0.20 ENST00000438819.1
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr6_-_119031228 0.20 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L
centrosomal protein 85kDa-like
chr12_-_76461249 0.20 ENST00000551524.1
NAP1L1
nucleosome assembly protein 1-like 1
chr9_-_69229650 0.20 ENST00000416428.1
CBWD6
COBW domain containing 6
chr17_+_58018269 0.19 ENST00000591035.1
RP11-178C3.1
Uncharacterized protein
chr3_-_57233966 0.19 ENST00000473921.1
ENST00000295934.3
HESX1
HESX homeobox 1
chr12_+_25205666 0.19 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr1_+_154377669 0.19 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr19_-_58446721 0.19 ENST00000396147.1
ENST00000595569.1
ENST00000599852.1
ENST00000425570.3
ENST00000601593.1
ZNF418
zinc finger protein 418
chr2_-_27886460 0.19 ENST00000404798.2
ENST00000405491.1
ENST00000464789.2
ENST00000406540.1
SUPT7L
suppressor of Ty 7 (S. cerevisiae)-like
chr1_+_104615595 0.19 ENST00000418362.1
RP11-364B6.1
RP11-364B6.1
chr4_+_71600063 0.19 ENST00000513597.1
RUFY3
RUN and FYVE domain containing 3
chr7_-_35013217 0.19 ENST00000446375.1
DPY19L1
dpy-19-like 1 (C. elegans)
chr8_-_36636676 0.18 ENST00000524132.1
ENST00000519451.1
RP11-962G15.1
RP11-962G15.1
chr13_-_79233314 0.18 ENST00000282003.6
RNF219
ring finger protein 219
chr15_+_76352178 0.17 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr9_+_131684027 0.17 ENST00000426694.1
PHYHD1
phytanoyl-CoA dioxygenase domain containing 1
chr5_+_138209688 0.17 ENST00000518381.1
CTNNA1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr5_+_112849373 0.17 ENST00000161863.4
ENST00000515883.1
YTHDC2
YTH domain containing 2
chr3_+_119298523 0.17 ENST00000357003.3
ADPRH
ADP-ribosylarginine hydrolase
chr19_+_56813305 0.17 ENST00000593151.1
AC006116.20
Uncharacterized protein
chr9_+_72658490 0.17 ENST00000377182.4
MAMDC2
MAM domain containing 2
chr6_-_31514516 0.17 ENST00000303892.5
ENST00000483251.1
ATP6V1G2
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr8_-_27695552 0.17 ENST00000522944.1
ENST00000301905.4
PBK
PDZ binding kinase
chrX_-_80457385 0.17 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
HMGN5
high mobility group nucleosome binding domain 5
chr11_+_27062272 0.17 ENST00000529202.1
ENST00000533566.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr2_-_102003987 0.17 ENST00000324768.5
CREG2
cellular repressor of E1A-stimulated genes 2
chr12_+_41136144 0.17 ENST00000548005.1
ENST00000552248.1
CNTN1
contactin 1
chr7_-_108209897 0.16 ENST00000313516.5
THAP5
THAP domain containing 5
chr4_-_185275104 0.16 ENST00000317596.3
RP11-290F5.2
RP11-290F5.2
chr20_+_12989596 0.16 ENST00000434210.1
ENST00000399002.2
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr11_+_122753391 0.16 ENST00000307257.6
ENST00000227349.2
C11orf63
chromosome 11 open reading frame 63
chr1_+_214776516 0.16 ENST00000366955.3
CENPF
centromere protein F, 350/400kDa
chr15_+_49715293 0.16 ENST00000267843.4
ENST00000560270.1
FGF7
fibroblast growth factor 7
chr15_+_96904487 0.16 ENST00000600790.1
AC087477.1
Uncharacterized protein
chr2_+_190722119 0.16 ENST00000452382.1
PMS1
PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
chr2_-_152146385 0.16 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr16_-_66764119 0.16 ENST00000569320.1
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chrX_+_119737806 0.16 ENST00000371317.5
MCTS1
malignant T cell amplified sequence 1
chr15_-_38519066 0.16 ENST00000561320.1
ENST00000561161.1
RP11-346D14.1
RP11-346D14.1
chr11_+_122733011 0.16 ENST00000533709.1
CRTAM
cytotoxic and regulatory T cell molecule
chr15_+_23255242 0.16 ENST00000450802.3
GOLGA8I
golgin A8 family, member I
chr10_-_4720333 0.16 ENST00000430998.2
LINC00704
long intergenic non-protein coding RNA 704
chr4_-_113627966 0.16 ENST00000505632.1
RP11-148B6.2
RP11-148B6.2
chr8_+_125486939 0.16 ENST00000303545.3
RNF139
ring finger protein 139
chrX_-_100604184 0.15 ENST00000372902.3
TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr3_-_93692781 0.15 ENST00000394236.3
PROS1
protein S (alpha)
chr11_-_59633951 0.15 ENST00000257264.3
TCN1
transcobalamin I (vitamin B12 binding protein, R binder family)
chr4_-_100356551 0.15 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr21_-_30365136 0.15 ENST00000361371.5
ENST00000389194.2
ENST00000389195.2
LTN1
listerin E3 ubiquitin protein ligase 1
chr10_-_98273668 0.15 ENST00000357947.3
TLL2
tolloid-like 2
chr9_+_104161123 0.15 ENST00000374861.3
ENST00000339664.2
ENST00000259395.4
ZNF189
zinc finger protein 189
chr20_+_12989822 0.15 ENST00000378194.4
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr20_-_55934878 0.15 ENST00000543500.1
MTRNR2L3
MT-RNR2-like 3
chr12_+_19593515 0.15 ENST00000360995.4
AEBP2
AE binding protein 2
chr12_+_25205628 0.15 ENST00000554942.1
LRMP
lymphoid-restricted membrane protein
chr5_-_42887494 0.15 ENST00000514218.1
SEPP1
selenoprotein P, plasma, 1
chr1_-_54411255 0.14 ENST00000371377.3
HSPB11
heat shock protein family B (small), member 11
chr8_-_30002179 0.14 ENST00000320542.3
MBOAT4
membrane bound O-acyltransferase domain containing 4
chr4_-_70626430 0.14 ENST00000310613.3
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr12_-_91573132 0.14 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr16_+_50099852 0.14 ENST00000299192.7
ENST00000285767.4
HEATR3
HEAT repeat containing 3
chr15_-_45459704 0.14 ENST00000558039.1
CTD-2651B20.1
CTD-2651B20.1
chr9_+_125133315 0.14 ENST00000223423.4
ENST00000362012.2
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr1_-_152131703 0.14 ENST00000316073.3
RPTN
repetin
chr4_+_74301880 0.14 ENST00000395792.2
ENST00000226359.2
AFP
alpha-fetoprotein
chr11_-_18956556 0.14 ENST00000302797.3
MRGPRX1
MAS-related GPR, member X1
chr16_+_15596123 0.14 ENST00000452191.2
C16orf45
chromosome 16 open reading frame 45
chr7_-_22862406 0.13 ENST00000372879.4
TOMM7
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr1_+_112016414 0.13 ENST00000343534.5
ENST00000369718.3
C1orf162
chromosome 1 open reading frame 162
chr10_+_5238793 0.13 ENST00000263126.1
AKR1C4
aldo-keto reductase family 1, member C4
chr6_-_13621126 0.13 ENST00000600057.1
AL441883.1
Uncharacterized protein
chr16_-_28634874 0.13 ENST00000395609.1
ENST00000350842.4
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr3_-_156272924 0.13 ENST00000467789.1
ENST00000265044.2
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr7_+_74379083 0.13 ENST00000361825.7
GATSL1
GATS protein-like 1
chr7_-_7606626 0.13 ENST00000609497.1
RP5-1159O4.1
RP5-1159O4.1
chr2_+_161993465 0.13 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr12_-_75784669 0.13 ENST00000552497.1
ENST00000551829.1
ENST00000436898.1
ENST00000442339.2
CAPS2
calcyphosine 2
chr4_+_38511367 0.13 ENST00000507056.1
RP11-213G21.1
RP11-213G21.1
chr8_-_42360015 0.13 ENST00000522707.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr16_+_66442411 0.12 ENST00000499966.1
LINC00920
long intergenic non-protein coding RNA 920
chr2_+_54342574 0.12 ENST00000303536.4
ENST00000394666.3
ACYP2
acylphosphatase 2, muscle type
chr13_-_33002151 0.12 ENST00000495479.1
ENST00000343281.4
ENST00000464470.1
ENST00000380139.4
ENST00000380133.2
N4BP2L1
NEDD4 binding protein 2-like 1
chr18_+_74240756 0.12 ENST00000584910.1
ENST00000582452.1
LINC00908
long intergenic non-protein coding RNA 908
chr3_-_46608010 0.12 ENST00000395905.3
LRRC2
leucine rich repeat containing 2
chrX_+_95939638 0.12 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
DIAPH2
diaphanous-related formin 2
chr19_+_2819854 0.12 ENST00000317243.5
ZNF554
zinc finger protein 554
chr18_+_11851383 0.12 ENST00000526991.2
CHMP1B
charged multivesicular body protein 1B
chr13_-_48612067 0.12 ENST00000543413.1
SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chr6_-_33771757 0.12 ENST00000507738.1
ENST00000266003.5
ENST00000430124.2
MLN
motilin
chr12_+_40787194 0.12 ENST00000425730.2
ENST00000454784.4
MUC19
mucin 19, oligomeric
chr1_-_59012365 0.12 ENST00000456980.1
ENST00000482274.2
ENST00000453710.1
ENST00000419242.1
ENST00000358603.2
ENST00000371226.3
ENST00000426139.1
OMA1
OMA1 zinc metallopeptidase
chr1_-_247171347 0.12 ENST00000339986.7
ENST00000487338.2
ZNF695
zinc finger protein 695
chr3_-_150264272 0.12 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
SERP1
stress-associated endoplasmic reticulum protein 1
chr2_-_99871570 0.12 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
LYG2
lysozyme G-like 2
chr4_+_70916119 0.12 ENST00000246896.3
ENST00000511674.1
HTN1
histatin 1
chr10_-_15902449 0.12 ENST00000277632.3
FAM188A
family with sequence similarity 188, member A
chr11_-_111649074 0.12 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr19_+_37960466 0.11 ENST00000589725.1
ZNF570
zinc finger protein 570
chr6_-_45345597 0.11 ENST00000371460.1
ENST00000371459.1
SUPT3H
suppressor of Ty 3 homolog (S. cerevisiae)
chr12_-_3982548 0.11 ENST00000397096.2
ENST00000447133.3
ENST00000450737.2
PARP11
poly (ADP-ribose) polymerase family, member 11
chr3_+_186692745 0.11 ENST00000438590.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr10_+_62538248 0.11 ENST00000448257.2
CDK1
cyclin-dependent kinase 1
chr12_+_128399965 0.11 ENST00000540882.1
ENST00000542089.1
LINC00507
long intergenic non-protein coding RNA 507
chr22_-_29107919 0.11 ENST00000434810.1
ENST00000456369.1
CHEK2
checkpoint kinase 2
chr8_-_125486755 0.11 ENST00000499418.2
ENST00000530778.1
RNF139-AS1
RNF139 antisense RNA 1 (head to head)
chr14_+_51955831 0.11 ENST00000356218.4
FRMD6
FERM domain containing 6
chr11_-_104893863 0.11 ENST00000260315.3
ENST00000526056.1
ENST00000531367.1
ENST00000456094.1
ENST00000444749.2
ENST00000393141.2
ENST00000418434.1
ENST00000393139.2
CASP5
caspase 5, apoptosis-related cysteine peptidase
chr2_-_192016276 0.11 ENST00000413064.1
STAT4
signal transducer and activator of transcription 4
chr14_+_52164820 0.11 ENST00000554167.1
FRMD6
FERM domain containing 6
chr1_+_32379174 0.11 ENST00000391369.1
AL136115.1
HCG2032337; PRO1848; Uncharacterized protein
chr3_+_48264816 0.11 ENST00000296435.2
ENST00000576243.1
CAMP
cathelicidin antimicrobial peptide
chr5_-_137475071 0.11 ENST00000265191.2
NME5
NME/NM23 family member 5
chr3_+_186743261 0.11 ENST00000423451.1
ENST00000446170.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr15_+_92006567 0.11 ENST00000554333.1
RP11-661P17.1
RP11-661P17.1
chr6_+_63921399 0.11 ENST00000356170.3
FKBP1C
FK506 binding protein 1C
chr7_-_105221898 0.11 ENST00000486180.1
ENST00000485614.1
ENST00000480514.1
EFCAB10
EF-hand calcium binding domain 10
chr5_-_33297946 0.11 ENST00000510327.1
CTD-2066L21.3
CTD-2066L21.3
chr6_-_24720226 0.11 ENST00000378102.3
C6orf62
chromosome 6 open reading frame 62
chr12_-_102455902 0.11 ENST00000240079.6
CCDC53
coiled-coil domain containing 53
chr4_+_83956312 0.11 ENST00000509317.1
ENST00000503682.1
ENST00000511653.1
COPS4
COP9 signalosome subunit 4
chr11_+_117947724 0.11 ENST00000534111.1
TMPRSS4
transmembrane protease, serine 4
chr5_+_111755280 0.11 ENST00000600409.1
EPB41L4A-AS2
EPB41L4A antisense RNA 2 (head to head)
chr4_-_140005341 0.11 ENST00000379549.2
ENST00000512627.1
ELF2
E74-like factor 2 (ets domain transcription factor)
chr8_-_93978309 0.10 ENST00000517858.1
ENST00000378861.5
TRIQK
triple QxxK/R motif containing
chr1_+_24646263 0.10 ENST00000524724.1
GRHL3
grainyhead-like 3 (Drosophila)
chr1_-_197115818 0.10 ENST00000367409.4
ENST00000294732.7
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr3_-_46786245 0.10 ENST00000442359.2
PRSS45
protease, serine, 45
chr12_+_56401268 0.10 ENST00000262032.5
IKZF4
IKAROS family zinc finger 4 (Eos)
chr14_-_54908043 0.10 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
CNIH1
cornichon family AMPA receptor auxiliary protein 1
chr4_-_140005443 0.10 ENST00000510408.1
ENST00000420916.2
ENST00000358635.3
ELF2
E74-like factor 2 (ets domain transcription factor)
chr8_-_17941575 0.10 ENST00000417108.2
ASAH1
N-acylsphingosine amidohydrolase (acid ceramidase) 1
chr16_-_21289627 0.10 ENST00000396023.2
ENST00000415987.2
CRYM
crystallin, mu
chr12_-_79849240 0.10 ENST00000550268.1
RP1-78O14.1
RP1-78O14.1
chr11_+_17316870 0.10 ENST00000458064.2
NUCB2
nucleobindin 2
chr17_-_59668550 0.10 ENST00000521764.1
NACA2
nascent polypeptide-associated complex alpha subunit 2
chr19_-_4535233 0.10 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5
perilipin 5
chr5_+_59783540 0.10 ENST00000515734.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr1_+_74663896 0.10 ENST00000370898.3
ENST00000467578.2
ENST00000370894.5
ENST00000482102.2
ENST00000609362.1
ENST00000534056.1
ENST00000557284.2
ENST00000370899.3
ENST00000370895.1
ENST00000534632.1
ENST00000370893.1
ENST00000370891.2
FPGT
FPGT-TNNI3K
TNNI3K
fucose-1-phosphate guanylyltransferase
FPGT-TNNI3K readthrough
TNNI3 interacting kinase
chr19_-_9879293 0.10 ENST00000397902.2
ENST00000592859.1
ENST00000588267.1
ZNF846
zinc finger protein 846
chr2_-_188378368 0.10 ENST00000392365.1
ENST00000435414.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr12_-_10022735 0.10 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr9_+_2029019 0.10 ENST00000382194.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr5_+_54455946 0.10 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
GPX8
glutathione peroxidase 8 (putative)
chr7_+_117824210 0.10 ENST00000422760.1
ENST00000411938.1
NAA38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr11_-_26593779 0.10 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr12_+_117013656 0.10 ENST00000556529.1
MAP1LC3B2
microtubule-associated protein 1 light chain 3 beta 2
chr17_-_65242063 0.10 ENST00000581159.1
HELZ
helicase with zinc finger
chr11_-_96123022 0.10 ENST00000542662.1
CCDC82
coiled-coil domain containing 82
chr17_+_44701402 0.10 ENST00000575068.1
NSF
N-ethylmaleimide-sensitive factor
chr9_-_21482312 0.10 ENST00000448696.3
IFNE
interferon, epsilon
chr19_-_52598958 0.10 ENST00000594440.1
ENST00000426391.2
ENST00000389534.4
ZNF841
zinc finger protein 841
chr1_-_205391178 0.10 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1
LEM domain containing 1
chr12_+_28605426 0.10 ENST00000542801.1
CCDC91
coiled-coil domain containing 91
chr12_+_128399917 0.10 ENST00000544645.1
LINC00507
long intergenic non-protein coding RNA 507
chr5_-_76788024 0.10 ENST00000515253.1
ENST00000414719.2
ENST00000507654.1
ENST00000514559.1
ENST00000511791.1
WDR41
WD repeat domain 41
chr1_+_104159999 0.10 ENST00000414303.2
ENST00000423678.1
AMY2A
amylase, alpha 2A (pancreatic)
chr10_+_94352956 0.10 ENST00000260731.3
KIF11
kinesin family member 11
chr4_+_144106063 0.10 ENST00000510377.1
USP38
ubiquitin specific peptidase 38
chr3_+_108321623 0.10 ENST00000497905.1
ENST00000463306.1
DZIP3
DAZ interacting zinc finger protein 3
chr15_-_52030293 0.10 ENST00000560491.1
ENST00000267838.3
LYSMD2
LysM, putative peptidoglycan-binding, domain containing 2
chr13_+_28519343 0.09 ENST00000381026.3
ATP5EP2
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2
chr4_+_95128748 0.09 ENST00000359052.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr19_+_53517174 0.09 ENST00000602168.1
ERVV-1
endogenous retrovirus group V, member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.4 GO:0060437 lung growth(GO:0060437)
0.1 0.3 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.1 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.6 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.2 GO:0045354 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.2 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.1 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.1 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.2 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.0 0.1 GO:2000437 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.0 0.2 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.1 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.0 0.2 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.2 GO:1900003 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.1 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:2000257 regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.0 0.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0070893 transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895)
0.0 0.2 GO:1901189 arterial endothelial cell fate commitment(GO:0060844) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.1 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.2 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.2 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508) regulation of chromosome condensation(GO:0060623)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.0 GO:0008037 cell recognition(GO:0008037)
0.0 0.1 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.4 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.2 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.0 0.0 GO:2000816 negative regulation of mitotic sister chromatid separation(GO:2000816)
0.0 0.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.3 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.2 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.3 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.0 GO:0007618 mating(GO:0007618)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0070839 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.0 0.0 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.0 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.0 0.0 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.1 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.0 0.3 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.2 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.2 GO:0042448 progesterone metabolic process(GO:0042448)
0.0 0.1 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.0 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.0 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0061015 snRNA import into nucleus(GO:0061015)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.0 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.1 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.2 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.3 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.0 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.0 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.0 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993)
0.0 0.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.0 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.0 GO:0000811 GINS complex(GO:0000811)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.3 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.2 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.3 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.2 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.2 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.2 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.2 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.1 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0070260 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.2 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.1 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.2 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.1 GO:0031862 prostanoid receptor binding(GO:0031862)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.0 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.0 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.0 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.0 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.0 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.4 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus