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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXB6_PRRX2

Z-value: 1.13

Motif logo

Transcription factors associated with HOXB6_PRRX2

Gene Symbol Gene ID Gene Info
ENSG00000108511.8 HOXB6
ENSG00000167157.9 PRRX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PRRX2hg19_v2_chr9_+_132427883_132427951-0.721.1e-01Click!
HOXB6hg19_v2_chr17_-_46682321_46682362-0.592.1e-01Click!

Activity profile of HOXB6_PRRX2 motif

Sorted Z-values of HOXB6_PRRX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB6_PRRX2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_-_84122033 2.23 ENST00000424555.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr9_-_3469181 1.58 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr7_-_84121858 1.49 ENST00000448879.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr1_+_61869748 0.99 ENST00000357977.5
NFIA
nuclear factor I/A
chr17_+_39846114 0.97 ENST00000586699.1
EIF1
eukaryotic translation initiation factor 1
chr14_-_54418598 0.94 ENST00000609748.1
ENST00000558961.1
BMP4
bone morphogenetic protein 4
chr4_-_153274078 0.93 ENST00000263981.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr5_-_24645078 0.93 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr4_-_36245561 0.93 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr18_-_53089723 0.92 ENST00000561992.1
ENST00000562512.2
TCF4
transcription factor 4
chr18_-_53019208 0.88 ENST00000562607.1
TCF4
transcription factor 4
chr4_+_108815402 0.88 ENST00000503385.1
SGMS2
sphingomyelin synthase 2
chr8_-_95449155 0.86 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr4_-_176733897 0.82 ENST00000393658.2
GPM6A
glycoprotein M6A
chr9_+_2159850 0.79 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_-_55237484 0.78 ENST00000394609.2
RTN4
reticulon 4
chrX_-_45629661 0.77 ENST00000602507.1
ENST00000602461.1
RP6-99M1.2
RP6-99M1.2
chr8_-_102803163 0.73 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD
neurocalcin delta
chr15_+_96904487 0.69 ENST00000600790.1
AC087477.1
Uncharacterized protein
chr13_-_36050819 0.69 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr1_+_84630053 0.67 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr8_+_104831472 0.67 ENST00000262231.10
ENST00000507740.1
RIMS2
regulating synaptic membrane exocytosis 2
chr20_+_5987890 0.67 ENST00000378868.4
CRLS1
cardiolipin synthase 1
chr9_+_2158485 0.67 ENST00000417599.1
ENST00000382185.1
ENST00000382183.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_+_168250194 0.65 ENST00000367821.3
TBX19
T-box 19
chr8_-_72268721 0.64 ENST00000419131.1
ENST00000388743.2
EYA1
eyes absent homolog 1 (Drosophila)
chr15_+_49715449 0.63 ENST00000560979.1
FGF7
fibroblast growth factor 7
chr9_+_2158443 0.63 ENST00000302401.3
ENST00000324954.5
ENST00000423555.1
ENST00000382186.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr17_+_4692230 0.59 ENST00000331264.7
GLTPD2
glycolipid transfer protein domain containing 2
chr12_+_2912363 0.57 ENST00000544366.1
FKBP4
FK506 binding protein 4, 59kDa
chr6_+_144606817 0.55 ENST00000433557.1
UTRN
utrophin
chr1_+_62439037 0.54 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr2_-_111291587 0.51 ENST00000437167.1
RGPD6
RANBP2-like and GRIP domain containing 6
chr15_+_96869165 0.51 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr4_+_160188306 0.51 ENST00000510510.1
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr13_-_86373536 0.51 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr11_-_85430088 0.51 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chr11_-_85430204 0.49 ENST00000389958.3
ENST00000527794.1
SYTL2
synaptotagmin-like 2
chr5_-_1882858 0.48 ENST00000511126.1
ENST00000231357.2
IRX4
iroquois homeobox 4
chr8_-_72268968 0.48 ENST00000388740.3
EYA1
eyes absent homolog 1 (Drosophila)
chr12_+_28410128 0.47 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr15_+_36994210 0.46 ENST00000562489.1
C15orf41
chromosome 15 open reading frame 41
chr8_+_42873548 0.45 ENST00000533338.1
ENST00000534420.1
HOOK3
RP11-598P20.5
hook microtubule-tethering protein 3
Uncharacterized protein
chr1_-_116383738 0.45 ENST00000320238.3
NHLH2
nescient helix loop helix 2
chrX_-_119693745 0.45 ENST00000371323.2
CUL4B
cullin 4B
chr1_-_152131703 0.44 ENST00000316073.3
RPTN
repetin
chr12_+_80838126 0.44 ENST00000266688.5
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chrX_+_123097014 0.43 ENST00000394478.1
STAG2
stromal antigen 2
chr16_+_86612112 0.43 ENST00000320241.3
FOXL1
forkhead box L1
chr1_-_68698197 0.43 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr3_+_69985734 0.43 ENST00000314557.6
ENST00000394351.3
MITF
microphthalmia-associated transcription factor
chr14_-_54423529 0.43 ENST00000245451.4
ENST00000559087.1
BMP4
bone morphogenetic protein 4
chr1_+_84629976 0.42 ENST00000446538.1
ENST00000370684.1
ENST00000436133.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_+_167298281 0.42 ENST00000367862.5
POU2F1
POU class 2 homeobox 1
chr1_+_205682497 0.42 ENST00000598338.1
AC119673.1
AC119673.1
chr3_+_69928256 0.41 ENST00000394355.2
MITF
microphthalmia-associated transcription factor
chr7_-_27183263 0.41 ENST00000222726.3
HOXA5
homeobox A5
chr5_+_67586465 0.41 ENST00000336483.5
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr15_+_49715293 0.41 ENST00000267843.4
ENST00000560270.1
FGF7
fibroblast growth factor 7
chr5_+_102200948 0.41 ENST00000511477.1
ENST00000506006.1
ENST00000509832.1
PAM
peptidylglycine alpha-amidating monooxygenase
chr9_+_67977438 0.40 ENST00000456982.1
RP11-195B21.3
Protein LOC644249
chr3_-_196911002 0.40 ENST00000452595.1
DLG1
discs, large homolog 1 (Drosophila)
chr2_-_99871570 0.40 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
LYG2
lysozyme G-like 2
chr5_+_138209688 0.39 ENST00000518381.1
CTNNA1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr12_-_10601963 0.39 ENST00000543893.1
KLRC1
killer cell lectin-like receptor subfamily C, member 1
chr2_+_210444748 0.38 ENST00000392194.1
MAP2
microtubule-associated protein 2
chr2_+_210444298 0.38 ENST00000445941.1
MAP2
microtubule-associated protein 2
chr6_-_56716686 0.38 ENST00000520645.1
DST
dystonin
chr15_-_33447055 0.38 ENST00000559047.1
ENST00000561249.1
FMN1
formin 1
chr2_+_17997763 0.37 ENST00000281047.3
MSGN1
mesogenin 1
chr8_-_42358742 0.37 ENST00000517366.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr15_+_96876340 0.37 ENST00000453270.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr4_-_184243561 0.36 ENST00000514470.1
ENST00000541814.1
CLDN24
claudin 24
chr16_-_3422283 0.36 ENST00000399974.3
MTRNR2L4
MT-RNR2-like 4
chr3_+_69812701 0.36 ENST00000472437.1
MITF
microphthalmia-associated transcription factor
chr20_+_52105495 0.35 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr2_-_136678123 0.35 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr3_-_57233966 0.34 ENST00000473921.1
ENST00000295934.3
HESX1
HESX homeobox 1
chr11_-_85430163 0.34 ENST00000529581.1
ENST00000533577.1
SYTL2
synaptotagmin-like 2
chr1_-_68698222 0.34 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr4_+_129730947 0.34 ENST00000452328.2
ENST00000504089.1
PHF17
jade family PHD finger 1
chr18_-_53089538 0.33 ENST00000566777.1
TCF4
transcription factor 4
chr1_+_95616933 0.33 ENST00000604203.1
RP11-57H12.6
TMEM56-RWDD3 readthrough
chr11_+_12108410 0.33 ENST00000527997.1
RP13-631K18.5
RP13-631K18.5
chr18_-_24237339 0.33 ENST00000580191.1
KCTD1
potassium channel tetramerization domain containing 1
chr9_+_109685630 0.33 ENST00000451160.2
RP11-508N12.4
Uncharacterized protein
chr9_+_2015335 0.32 ENST00000349721.2
ENST00000357248.2
ENST00000450198.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_+_66662690 0.32 ENST00000488550.1
MEIS1
Meis homeobox 1
chr8_-_72268889 0.32 ENST00000388742.4
EYA1
eyes absent homolog 1 (Drosophila)
chr14_+_62462541 0.32 ENST00000430451.2
SYT16
synaptotagmin XVI
chr9_+_130026756 0.31 ENST00000314904.5
ENST00000373387.4
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr2_+_66662249 0.31 ENST00000560281.2
MEIS1
Meis homeobox 1
chr2_+_171034646 0.31 ENST00000409044.3
ENST00000408978.4
MYO3B
myosin IIIB
chr10_-_33623310 0.31 ENST00000395995.1
ENST00000374823.5
ENST00000374821.5
ENST00000374816.3
NRP1
neuropilin 1
chr4_+_160203650 0.30 ENST00000514565.1
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr3_-_196910721 0.30 ENST00000443183.1
DLG1
discs, large homolog 1 (Drosophila)
chr4_+_30723003 0.30 ENST00000543491.1
PCDH7
protocadherin 7
chr3_+_107243204 0.30 ENST00000456817.1
ENST00000458458.1
BBX
bobby sox homolog (Drosophila)
chr6_-_31107127 0.30 ENST00000259845.4
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr4_+_104346194 0.30 ENST00000510200.1
RP11-328K4.1
RP11-328K4.1
chr5_+_59783540 0.29 ENST00000515734.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr5_-_124082279 0.29 ENST00000513986.1
ZNF608
zinc finger protein 608
chr3_+_88188254 0.29 ENST00000309495.5
ZNF654
zinc finger protein 654
chr6_+_90272488 0.29 ENST00000485637.1
ENST00000522705.1
ANKRD6
ankyrin repeat domain 6
chr3_+_25469802 0.28 ENST00000330688.4
RARB
retinoic acid receptor, beta
chr4_+_129731074 0.28 ENST00000512960.1
ENST00000503785.1
ENST00000514740.1
PHF17
jade family PHD finger 1
chr5_-_111092930 0.28 ENST00000257435.7
NREP
neuronal regeneration related protein
chr10_-_21806759 0.28 ENST00000444772.3
SKIDA1
SKI/DACH domain containing 1
chr13_-_38172863 0.28 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN
periostin, osteoblast specific factor
chr2_+_190541153 0.28 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ANKAR
ankyrin and armadillo repeat containing
chr4_+_41614909 0.28 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr4_+_95174445 0.28 ENST00000509418.1
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr6_+_45296391 0.28 ENST00000371436.6
ENST00000576263.1
RUNX2
runt-related transcription factor 2
chr1_+_84630645 0.28 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr4_-_111563076 0.28 ENST00000354925.2
ENST00000511990.1
PITX2
paired-like homeodomain 2
chr2_+_210443993 0.28 ENST00000392193.1
MAP2
microtubule-associated protein 2
chr13_+_31774073 0.28 ENST00000343307.4
B3GALTL
beta 1,3-galactosyltransferase-like
chr9_-_13165457 0.27 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ
multiple PDZ domain protein
chr1_+_78470530 0.27 ENST00000370763.5
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr2_+_162101247 0.27 ENST00000439050.1
ENST00000436506.1
AC009299.3
AC009299.3
chr5_-_111093167 0.27 ENST00000446294.2
ENST00000419114.2
NREP
neuronal regeneration related protein
chr20_+_58571419 0.27 ENST00000244049.3
ENST00000350849.6
ENST00000456106.1
CDH26
cadherin 26
chr14_-_77495007 0.27 ENST00000238647.3
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr6_-_56507586 0.26 ENST00000439203.1
ENST00000518935.1
ENST00000446842.2
ENST00000370765.6
ENST00000244364.6
DST
dystonin
chr6_-_33160231 0.26 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2
collagen, type XI, alpha 2
chr17_+_57233087 0.26 ENST00000578777.1
ENST00000577457.1
ENST00000582995.1
PRR11
proline rich 11
chr8_-_90993869 0.26 ENST00000517772.1
NBN
nibrin
chr2_+_191792376 0.26 ENST00000409428.1
ENST00000409215.1
GLS
glutaminase
chr2_+_103089756 0.26 ENST00000295269.4
SLC9A4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chr20_+_32150140 0.25 ENST00000344201.3
ENST00000346541.3
ENST00000397800.1
ENST00000397798.2
ENST00000492345.1
CBFA2T2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr2_-_177502659 0.25 ENST00000295549.4
AC017048.3
long intergenic non-protein coding RNA 1116
chr4_+_74301880 0.25 ENST00000395792.2
ENST00000226359.2
AFP
alpha-fetoprotein
chr4_-_99578776 0.25 ENST00000515287.1
TSPAN5
tetraspanin 5
chr16_+_70695570 0.25 ENST00000597002.1
FLJ00418
FLJ00418
chr15_+_96875657 0.24 ENST00000559679.1
ENST00000394171.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr7_-_27179814 0.24 ENST00000522788.1
ENST00000521779.1
HOXA3
homeobox A3
chr5_+_59783941 0.24 ENST00000506884.1
ENST00000504876.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr7_-_111428957 0.24 ENST00000417165.1
DOCK4
dedicator of cytokinesis 4
chr7_-_27170352 0.24 ENST00000428284.2
ENST00000360046.5
HOXA4
homeobox A4
chr6_+_155537771 0.24 ENST00000275246.7
TIAM2
T-cell lymphoma invasion and metastasis 2
chr4_+_170581213 0.23 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chrX_-_117119243 0.23 ENST00000539496.1
ENST00000469946.1
KLHL13
kelch-like family member 13
chr3_+_69812877 0.23 ENST00000457080.1
ENST00000328528.6
MITF
microphthalmia-associated transcription factor
chr22_+_50925213 0.23 ENST00000395733.3
ENST00000216075.6
ENST00000395732.3
MIOX
myo-inositol oxygenase
chr12_+_25205446 0.23 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP
lymphoid-restricted membrane protein
chr6_+_149721495 0.23 ENST00000326669.4
SUMO4
small ubiquitin-like modifier 4
chr1_-_108507631 0.23 ENST00000527011.1
ENST00000370056.4
VAV3
vav 3 guanine nucleotide exchange factor
chr2_+_66662510 0.23 ENST00000272369.9
ENST00000407092.2
MEIS1
Meis homeobox 1
chr5_+_173316341 0.22 ENST00000520867.1
ENST00000334035.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr4_-_23891693 0.22 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr8_-_80993010 0.22 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
TPD52
tumor protein D52
chr8_+_97773202 0.22 ENST00000519484.1
CPQ
carboxypeptidase Q
chr1_-_23886285 0.22 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr7_-_27169801 0.22 ENST00000511914.1
HOXA4
homeobox A4
chr5_-_130868688 0.22 ENST00000504575.1
ENST00000513227.1
RAPGEF6
Rap guanine nucleotide exchange factor (GEF) 6
chr2_+_145780767 0.22 ENST00000599358.1
ENST00000596278.1
ENST00000596747.1
ENST00000608652.1
ENST00000609705.1
ENST00000608432.1
ENST00000596970.1
ENST00000602041.1
ENST00000601578.1
ENST00000596034.1
ENST00000414195.2
ENST00000594837.1
TEX41
testis expressed 41 (non-protein coding)
chr16_+_53133070 0.22 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr11_-_13461790 0.22 ENST00000530907.1
BTBD10
BTB (POZ) domain containing 10
chr3_-_196987309 0.22 ENST00000453607.1
DLG1
discs, large homolog 1 (Drosophila)
chr7_+_102553430 0.22 ENST00000339431.4
ENST00000249377.4
LRRC17
leucine rich repeat containing 17
chr11_-_16419067 0.22 ENST00000533411.1
SOX6
SRY (sex determining region Y)-box 6
chr3_-_196910477 0.22 ENST00000447466.1
DLG1
discs, large homolog 1 (Drosophila)
chr4_-_68620053 0.21 ENST00000420975.2
ENST00000226413.4
GNRHR
gonadotropin-releasing hormone receptor
chr8_-_37594944 0.21 ENST00000330539.1
RP11-863K10.7
Uncharacterized protein
chr11_-_85430356 0.21 ENST00000526999.1
SYTL2
synaptotagmin-like 2
chr5_-_124081008 0.21 ENST00000306315.5
ZNF608
zinc finger protein 608
chr1_-_108231101 0.21 ENST00000544443.1
ENST00000415432.2
VAV3
vav 3 guanine nucleotide exchange factor
chr3_+_152017360 0.21 ENST00000485910.1
ENST00000463374.1
MBNL1
muscleblind-like splicing regulator 1
chr5_+_174151536 0.21 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chr5_-_124084493 0.21 ENST00000509799.1
ZNF608
zinc finger protein 608
chr5_+_39105358 0.21 ENST00000593965.1
AC008964.1
AC008964.1
chr6_+_111195973 0.21 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
AMD1
adenosylmethionine decarboxylase 1
chr10_+_111765562 0.21 ENST00000360162.3
ADD3
adducin 3 (gamma)
chr2_-_175462934 0.21 ENST00000392546.2
ENST00000436221.1
WIPF1
WAS/WASL interacting protein family, member 1
chr1_+_212475148 0.21 ENST00000537030.3
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr14_-_92413727 0.21 ENST00000267620.10
FBLN5
fibulin 5
chr8_-_17533838 0.21 ENST00000400046.1
MTUS1
microtubule associated tumor suppressor 1
chr12_-_118796910 0.21 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr17_+_75316336 0.21 ENST00000591934.1
SEPT9
septin 9
chr3_+_161214596 0.21 ENST00000327928.4
OTOL1
otolin 1
chr6_-_42418999 0.20 ENST00000340840.2
ENST00000354325.2
TRERF1
transcriptional regulating factor 1
chr7_-_83278322 0.20 ENST00000307792.3
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr2_-_224467093 0.20 ENST00000305409.2
SCG2
secretogranin II
chr8_-_133637624 0.20 ENST00000522789.1
LRRC6
leucine rich repeat containing 6
chr7_+_116451100 0.20 ENST00000464223.1
ENST00000484325.1
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr9_-_5830768 0.20 ENST00000381506.3
ERMP1
endoplasmic reticulum metallopeptidase 1
chr10_-_98031310 0.20 ENST00000427367.2
ENST00000413476.2
BLNK
B-cell linker
chr4_-_139163491 0.20 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr12_-_102591604 0.20 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr1_-_57045228 0.20 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr19_-_56110859 0.19 ENST00000221665.3
ENST00000592585.1
FIZ1
FLT3-interacting zinc finger 1
chr17_+_58018269 0.19 ENST00000591035.1
RP11-178C3.1
Uncharacterized protein
chr10_-_116418053 0.19 ENST00000277895.5
ABLIM1
actin binding LIM protein 1
chr4_+_15683369 0.19 ENST00000503617.1
FAM200B
family with sequence similarity 200, member B
chr1_+_174844645 0.19 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chr3_-_123339343 0.19 ENST00000578202.1
MYLK
myosin light chain kinase
chr8_+_26150628 0.19 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr12_+_21207503 0.19 ENST00000545916.1
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr6_-_116381918 0.19 ENST00000606080.1
FRK
fyn-related kinase
chr2_-_164592497 0.19 ENST00000333129.3
ENST00000409634.1
FIGN
fidgetin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.6 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.3 1.1 GO:0009956 radial pattern formation(GO:0009956)
0.3 1.4 GO:2000007 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.3 1.0 GO:0060437 lung growth(GO:0060437)
0.2 1.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.2 0.8 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.2 1.5 GO:0097338 response to clozapine(GO:0097338)
0.1 1.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 1.1 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.1 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.5 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 1.6 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.4 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.1 0.4 GO:0060127 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.1 0.1 GO:0097168 mesenchymal stem cell proliferation(GO:0097168)
0.1 0.8 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.1 0.3 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.3 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.7 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.1 0.4 GO:0060023 soft palate development(GO:0060023)
0.1 0.5 GO:0018032 protein amidation(GO:0018032)
0.1 1.0 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 0.2 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1 0.9 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.8 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.2 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.1 0.3 GO:0006959 humoral immune response(GO:0006959)
0.1 0.6 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.8 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.2 GO:0060913 cardiac cell fate determination(GO:0060913)
0.1 0.2 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) positive regulation of mitochondrial DNA metabolic process(GO:1901860) response to methionine(GO:1904640)
0.1 0.6 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.4 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.4 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.1 0.2 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.1 0.4 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 1.1 GO:0072189 ureter development(GO:0072189)
0.1 0.3 GO:0032571 response to vitamin K(GO:0032571)
0.1 0.2 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 0.3 GO:0046543 development of secondary sexual characteristics(GO:0045136) development of secondary female sexual characteristics(GO:0046543)
0.1 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.4 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 0.4 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.1 0.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.2 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.3 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.6 GO:0043010 camera-type eye development(GO:0043010)
0.1 0.2 GO:0010159 specification of organ position(GO:0010159)
0.0 0.8 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.2 GO:2000173 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0 0.2 GO:0035711 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711)
0.0 0.1 GO:0035150 regulation of tube size(GO:0035150) regulation of blood vessel size(GO:0050880)
0.0 0.3 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.0 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.2 GO:0010157 response to chlorate(GO:0010157)
0.0 0.2 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.1 GO:0002525 acute inflammatory response to non-antigenic stimulus(GO:0002525) regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.0 0.1 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.2 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.3 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.1 GO:0031106 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.0 0.1 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535) regulation of positive thymic T cell selection(GO:1902232)
0.0 0.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.1 GO:0050787 detoxification of mercury ion(GO:0050787)
0.0 0.9 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0 0.1 GO:0015747 urate transport(GO:0015747)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.1 GO:0060022 hard palate development(GO:0060022)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.6 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.2 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.0 0.2 GO:0030183 B cell differentiation(GO:0030183)
0.0 1.6 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.5 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.2 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.2 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.1 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.0 0.1 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.1 GO:0042245 RNA repair(GO:0042245)
0.0 0.1 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.5 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:0030856 regulation of epithelial cell differentiation(GO:0030856)
0.0 0.5 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.2 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.2 GO:1905066 positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.2 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:1901420 negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
0.0 0.1 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.1 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.0 0.3 GO:0021983 pituitary gland development(GO:0021983)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0090325 regulation of locomotion involved in locomotory behavior(GO:0090325)
0.0 0.0 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916) otic vesicle morphogenesis(GO:0071600)
0.0 0.1 GO:0021984 adenohypophysis development(GO:0021984)
0.0 0.1 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.5 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.2 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.1 GO:0050773 regulation of dendrite development(GO:0050773)
0.0 0.3 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.5 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0045446 endothelial cell differentiation(GO:0045446)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0046108 uridine metabolic process(GO:0046108)
0.0 0.1 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.5 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.0 GO:0035283 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.3 GO:0007379 segment specification(GO:0007379)
0.0 0.1 GO:0070839 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.0 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.3 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.0 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.2 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.2 GO:0009798 axis specification(GO:0009798)
0.0 0.0 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.0 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.2 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.1 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.1 GO:0030969 mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) mRNA endonucleolytic cleavage involved in unfolded protein response(GO:0070055) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.1 GO:0001835 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.1 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.2 GO:0060613 fat pad development(GO:0060613)
0.0 0.1 GO:0090493 dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0 2.4 GO:0007286 spermatid development(GO:0007286)
0.0 0.1 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.5 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.0 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.1 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.1 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.1 GO:0021942 regulation of definitive erythrocyte differentiation(GO:0010724) radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.0 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.4 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.1 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.3 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.4 GO:0072663 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.0 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0015811 L-cystine transport(GO:0015811)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 1.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.8 GO:0031673 H zone(GO:0031673)
0.1 0.9 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 2.4 GO:0071564 npBAF complex(GO:0071564)
0.1 1.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.4 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.5 GO:0070695 FHF complex(GO:0070695)
0.1 1.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.2 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.1 0.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.2 GO:1990032 parallel fiber(GO:1990032)
0.0 1.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.7 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.3 GO:0097443 sorting endosome(GO:0097443)
0.0 0.2 GO:0071565 nBAF complex(GO:0071565)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0097422 tubular endosome(GO:0097422)
0.0 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.4 GO:0070938 contractile ring(GO:0070938)
0.0 0.8 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.0 GO:0031430 M band(GO:0031430) A band(GO:0031672)
0.0 0.0 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.0 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 3.8 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.0 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.0 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.0 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.0 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.1 GO:0043296 apical junction complex(GO:0043296)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.2 3.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 0.7 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 3.0 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.6 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 1.0 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.9 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 1.1 GO:0097016 L27 domain binding(GO:0097016)
0.1 1.2 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.5 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.4 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.2 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.1 0.2 GO:0019808 polyamine binding(GO:0019808)
0.1 1.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.8 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 1.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.4 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.0 0.3 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 1.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 2.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0005334 norepinephrine:sodium symporter activity(GO:0005334)
0.0 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 1.0 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.3 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.9 GO:0002162 dystroglycan binding(GO:0002162)
0.0 1.5 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 1.1 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.3 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.2 GO:0005119 smoothened binding(GO:0005119)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.7 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0003712 transcription cofactor activity(GO:0003712)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.0 0.1 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.0 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.5 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.4 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.2 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.5 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0045295 gamma-catenin binding(GO:0045295)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.3 PID MYC PATHWAY C-MYC pathway
0.0 1.4 PID IL3 PATHWAY IL3-mediated signaling events
0.0 2.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 4.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 2.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.8 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.7 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 3.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.1 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.0 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.9 PID AURORA B PATHWAY Aurora B signaling
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.9 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.9 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 2.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.5 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.0 0.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.5 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle