Project
NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for HOXB2_UNCX_HOXD3
Z-value: 0.90
Motif logo
Transcription factors associated with HOXB2_UNCX_HOXD3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HOXB2 | hg19_v2_chr17_-_46623441_46623441 | 0.68 | 1.3e-01 | Click! |
| HOXD3 | hg19_v2_chr2_+_177015122_177015122 | -0.35 | 5.0e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of HOXB2_UNCX_HOXD3
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | GO:0006999 | nuclear pore organization(GO:0006999) |
| 0.1 | 1.0 | GO:0090234 | regulation of kinetochore assembly(GO:0090234) |
| 0.0 | 0.9 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.0 | 0.8 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
| 0.1 | 0.7 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
| 0.0 | 0.7 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
| 0.0 | 0.7 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.0 | 0.7 | GO:0006590 | thyroid hormone generation(GO:0006590) |
| 0.0 | 0.7 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.1 | 0.6 | GO:0031860 | telomeric 3' overhang formation(GO:0031860) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 0.9 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
| 0.1 | 0.8 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.0 | 0.8 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.0 | 0.7 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.0 | 0.7 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.0 | 0.7 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 0.6 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.0 | 0.6 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.0 | 0.6 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.1 | 1.0 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 0.0 | 1.0 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.3 | 0.8 | GO:0019781 | NEDD8 activating enzyme activity(GO:0019781) |
| 0.0 | 0.8 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.0 | 0.8 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.1 | 0.7 | GO:0070573 | metallodipeptidase activity(GO:0070573) |
| 0.1 | 0.7 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 0.0 | 0.7 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
| 0.0 | 0.7 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.0 | 0.8 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.0 | 0.7 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.0 | 0.4 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.0 | 0.3 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 0.2 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.0 | 0.1 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.0 | 0.0 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.0 | 1.2 | REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
| 0.0 | 1.1 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 0.8 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.0 | 0.7 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.0 | 0.7 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.0 | 0.6 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.0 | 0.6 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 0.5 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.0 | 0.5 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |