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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for HOXA13
Z-value: 0.72
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Transcription factors associated with HOXA13
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_-_41742697 Show fit | 0.66 |
ENST00000242208.4
|
inhibin, beta A |
|
| chr5_+_159895275 Show fit | 0.56 |
ENST00000517927.1
|
microRNA 146a |
|
| chr18_-_73967160 Show fit | 0.47 |
ENST00000579714.1
|
RP11-94B19.7 |
|
| chr15_-_79576156 Show fit | 0.46 |
ENST00000560452.1
ENST00000560872.1 ENST00000560732.1 ENST00000559979.1 ENST00000560533.1 ENST00000559225.1 |
RP11-17L5.4 |
|
| chr11_-_105010320 Show fit | 0.30 |
ENST00000532895.1
ENST00000530950.1 |
caspase recruitment domain family, member 18 |
|
| chr19_-_44809121 Show fit | 0.30 |
ENST00000591609.1
ENST00000589799.1 ENST00000291182.4 ENST00000589248.1 |
zinc finger protein 235 |
|
| chr7_-_17598506 Show fit | 0.29 |
ENST00000451792.1
|
AC017060.1 |
|
| chr4_-_101111615 Show fit | 0.28 |
ENST00000273990.2
|
DNA-damage-inducible transcript 4-like |
|
| chr12_-_53207842 Show fit | 0.27 |
ENST00000458244.2
|
keratin 4 |
|
| chr21_+_17792672 Show fit | 0.27 |
ENST00000602620.1
|
long intergenic non-protein coding RNA 478 |
Network of associatons between targets according to the STRING database.
First level regulatory network of HOXA13
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.7 | GO:0060279 | regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279) |
| 0.0 | 0.5 | GO:0043101 | purine-containing compound salvage(GO:0043101) |
| 0.0 | 0.3 | GO:0050713 | negative regulation of interleukin-1 beta secretion(GO:0050713) |
| 0.0 | 0.3 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.0 | 0.3 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
| 0.1 | 0.2 | GO:0061394 | regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) |
| 0.1 | 0.2 | GO:0051066 | dihydrobiopterin metabolic process(GO:0051066) |
| 0.0 | 0.2 | GO:0030573 | bile acid catabolic process(GO:0030573) |
| 0.0 | 0.2 | GO:0097045 | phosphatidylserine exposure on blood platelet(GO:0097045) |
| 0.0 | 0.2 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.7 | GO:0043512 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
| 0.1 | 0.5 | GO:1902560 | GMP reductase complex(GO:1902560) |
| 0.0 | 0.3 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.0 | 0.2 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.0 | 0.2 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.0 | 0.2 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
| 0.0 | 0.1 | GO:0034680 | integrin alpha10-beta1 complex(GO:0034680) |
| 0.0 | 0.1 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 0.0 | 0.1 | GO:0098839 | postsynaptic density membrane(GO:0098839) |
| 0.0 | 0.1 | GO:0044294 | dendritic growth cone(GO:0044294) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.7 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.1 | 0.5 | GO:0016657 | GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657) |
| 0.0 | 0.5 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.1 | 0.3 | GO:0047006 | 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) |
| 0.0 | 0.3 | GO:0089720 | caspase binding(GO:0089720) |
| 0.1 | 0.2 | GO:0004155 | 6,7-dihydropteridine reductase activity(GO:0004155) |
| 0.1 | 0.2 | GO:0047273 | galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273) |
| 0.0 | 0.2 | GO:0047787 | delta4-3-oxosteroid 5beta-reductase activity(GO:0047787) |
| 0.0 | 0.2 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.0 | 0.2 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.7 | PID ALK1 PATHWAY | ALK1 signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.7 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.0 | 0.5 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.0 | 0.5 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.0 | 0.2 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.0 | 0.2 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |