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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for HOXA10_HOXB9
Z-value: 0.25
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Transcription factors associated with HOXA10_HOXB9
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HOXA10 | hg19_v2_chr7_-_27213893_27213954 | -0.36 | 4.9e-01 | Click! |
| HOXB9 | hg19_v2_chr17_-_46703826_46703845 | -0.24 | 6.4e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr5_-_159766528 Show fit | 0.14 |
ENST00000505287.2
|
cyclin J-like |
|
| chr6_+_12958137 Show fit | 0.13 |
ENST00000457702.2
ENST00000379345.2 |
phosphatase and actin regulator 1 |
|
| chr6_+_26156551 Show fit | 0.13 |
ENST00000304218.3
|
histone cluster 1, H1e |
|
| chr6_+_46761118 Show fit | 0.11 |
ENST00000230588.4
|
meprin A, alpha (PABA peptide hydrolase) |
|
| chr8_-_71157595 Show fit | 0.11 |
ENST00000519724.1
|
nuclear receptor coactivator 2 |
|
| chr6_-_26250835 Show fit | 0.09 |
ENST00000446824.2
|
histone cluster 1, H3f |
|
| chr4_+_71384257 Show fit | 0.09 |
ENST00000339336.4
|
amelotin |
|
| chr7_+_141408153 Show fit | 0.09 |
ENST00000397541.2
|
WEE1 homolog 2 (S. pombe) |
|
| chr1_+_229440129 Show fit | 0.09 |
ENST00000366688.3
|
S-phase response (cyclin related) |
|
| chr2_+_101591314 Show fit | 0.08 |
ENST00000450763.1
|
neuronal PAS domain protein 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of HOXA10_HOXB9
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:1904017 | cellular response to Thyroglobulin triiodothyronine(GO:1904017) |
| 0.0 | 0.1 | GO:0035038 | female pronucleus assembly(GO:0035038) |
| 0.0 | 0.1 | GO:0042488 | positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) positive regulation of tooth mineralization(GO:0070172) |
| 0.0 | 0.1 | GO:0002384 | hepatic immune response(GO:0002384) |
| 0.0 | 0.1 | GO:0098532 | histone H3-K27 trimethylation(GO:0098532) |
| 0.0 | 0.1 | GO:0002636 | positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.0 | 0.1 | GO:1990423 | RZZ complex(GO:1990423) |
| 0.0 | 0.1 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.0 | 0.0 | GO:1990032 | parallel fiber(GO:1990032) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0070119 | ciliary neurotrophic factor binding(GO:0070119) |
| 0.0 | 0.1 | GO:0010861 | thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375) |
| 0.0 | 0.1 | GO:0032564 | adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564) |