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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXA10_HOXB9

Z-value: 0.25

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Transcription factors associated with HOXA10_HOXB9

Gene Symbol Gene ID Gene Info
ENSG00000253293.3 homeobox A10
ENSG00000170689.8 homeobox B9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA10hg19_v2_chr7_-_27213893_27213954-0.364.9e-01Click!
HOXB9hg19_v2_chr17_-_46703826_46703845-0.246.4e-01Click!

Activity profile of HOXA10_HOXB9 motif

Sorted Z-values of HOXA10_HOXB9 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_159766528 0.14 ENST00000505287.2
cyclin J-like
chr6_+_12958137 0.13 ENST00000457702.2
ENST00000379345.2
phosphatase and actin regulator 1
chr6_+_26156551 0.13 ENST00000304218.3
histone cluster 1, H1e
chr6_+_46761118 0.11 ENST00000230588.4
meprin A, alpha (PABA peptide hydrolase)
chr8_-_71157595 0.11 ENST00000519724.1
nuclear receptor coactivator 2
chr6_-_26250835 0.09 ENST00000446824.2
histone cluster 1, H3f
chr4_+_71384257 0.09 ENST00000339336.4
amelotin
chr7_+_141408153 0.09 ENST00000397541.2
WEE1 homolog 2 (S. pombe)
chr1_+_229440129 0.09 ENST00000366688.3
S-phase response (cyclin related)
chr2_+_101591314 0.08 ENST00000450763.1
neuronal PAS domain protein 2
chr3_-_138048682 0.08 ENST00000383180.2
NME/NM23 family member 9
chr19_+_21106028 0.08 ENST00000597314.1
ENST00000601924.1
zinc finger protein 85
chr7_+_79763271 0.08 ENST00000442586.1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr7_+_128784712 0.08 ENST00000289407.4
tetraspanin 33
chr19_-_3500635 0.08 ENST00000250937.3
deoxyhypusine hydroxylase/monooxygenase
chr14_+_73706308 0.08 ENST00000554301.1
ENST00000555445.1
papilin, proteoglycan-like sulfated glycoprotein
chr10_+_85933494 0.08 ENST00000372126.3
chromosome 10 open reading frame 99
chr1_+_153003671 0.08 ENST00000307098.4
small proline-rich protein 1B
chr18_+_3466248 0.07 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
chr2_+_149974684 0.07 ENST00000450639.1
LY6/PLAUR domain containing 6B
chr11_-_110968081 0.07 ENST00000603154.1
RP11-89C3.4
chr14_-_38028689 0.07 ENST00000553425.1
RP11-356O9.2
chr1_+_154401791 0.07 ENST00000476006.1
interleukin 6 receptor
chr16_-_25122735 0.07 ENST00000563176.1
RP11-449H11.1
chr8_+_145215928 0.07 ENST00000528919.1
maestro heat-like repeat family member 1
chr11_+_63606373 0.06 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MAP/microtubule affinity-regulating kinase 2
chr11_-_65359947 0.06 ENST00000597463.1
Uncharacterized protein
chr6_-_27782548 0.06 ENST00000333151.3
histone cluster 1, H2aj
chrX_+_48620147 0.06 ENST00000303227.6
glyoxalase domain containing 5
chr15_+_93749295 0.06 ENST00000599897.1
AC112693.2
chr14_+_35514323 0.06 ENST00000555211.1
family with sequence similarity 177, member A1
chr13_+_108921977 0.06 ENST00000430559.1
ENST00000375887.4
tumor necrosis factor (ligand) superfamily, member 13b
chr8_+_91233711 0.06 ENST00000523283.1
ENST00000517400.1
long intergenic non-protein coding RNA 534
chr6_+_32812568 0.06 ENST00000414474.1
proteasome (prosome, macropain) subunit, beta type, 9
chr21_+_30503282 0.05 ENST00000399925.1
MAP3K7 C-terminal like
chr17_+_61151306 0.05 ENST00000580068.1
ENST00000580466.1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr14_-_25479811 0.05 ENST00000550887.1
syntaxin binding protein 6 (amisyn)
chr2_-_32390801 0.05 ENST00000608489.1
RP11-563N4.1
chr1_+_151735431 0.05 ENST00000321531.5
ENST00000315067.8
ornithine decarboxylase antizyme 3
chr19_-_10420459 0.05 ENST00000403352.1
ENST00000403903.3
zinc finger, GATA-like protein 1
chr19_+_3185910 0.05 ENST00000588428.1
nicalin
chr11_-_7961141 0.05 ENST00000360759.3
olfactory receptor, family 10, subfamily A, member 3
chr1_+_67773044 0.05 ENST00000262345.1
ENST00000371000.1
interleukin 12 receptor, beta 2
chr12_-_94673956 0.05 ENST00000551941.1
Uncharacterized protein
chr2_+_38177575 0.05 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
regulator of microtubule dynamics 2
chr4_-_140222358 0.05 ENST00000505036.1
ENST00000544855.1
ENST00000539002.1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr4_+_71384300 0.04 ENST00000504451.1
amelotin
chr1_-_242162375 0.04 ENST00000357246.3
microtubule-associated protein 1 light chain 3 gamma
chr4_+_70894130 0.04 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
histatin 3
chr15_+_40886439 0.04 ENST00000532056.1
ENST00000399668.2
cancer susceptibility candidate 5
chr7_+_138915102 0.04 ENST00000486663.1
ubinuclein 2
chr15_+_66797627 0.04 ENST00000565627.1
ENST00000564179.1
zwilch kinetochore protein
chr15_+_67835517 0.04 ENST00000395476.2
mitogen-activated protein kinase kinase 5
chr3_+_140981456 0.04 ENST00000504264.1
acid phosphatase-like 2
chr11_+_61717279 0.04 ENST00000378043.4
bestrophin 1
chr11_+_61717336 0.04 ENST00000378042.3
bestrophin 1
chr5_-_176433565 0.04 ENST00000428382.2
ubiquitin interaction motif containing 1
chr2_-_207078086 0.04 ENST00000442134.1
G protein-coupled receptor 1
chr1_-_186430222 0.04 ENST00000391997.2
phosducin
chr16_-_30621663 0.04 ENST00000287461.3
zinc finger protein 689
chr22_-_22337146 0.03 ENST00000398793.2
topoisomerase (DNA) III beta
chr8_+_91233750 0.03 ENST00000523406.1
long intergenic non-protein coding RNA 534
chr3_-_180707306 0.03 ENST00000479269.1
DnaJ (Hsp40) homolog, subfamily C, member 19
chr10_+_135160844 0.03 ENST00000423766.1
ENST00000458230.1
proline-rich acidic protein 1
chr1_-_23521222 0.03 ENST00000374619.1
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr2_+_90192768 0.03 ENST00000390275.2
immunoglobulin kappa variable 1D-13
chr14_-_68000442 0.03 ENST00000554278.1
transmembrane protein 229B
chr9_+_124413873 0.03 ENST00000408936.3
DAB2 interacting protein
chr9_+_44868935 0.03 ENST00000448436.2
RP11-160N1.10
chr19_-_48759119 0.03 ENST00000522889.1
ENST00000520753.1
ENST00000519940.1
ENST00000519332.1
ENST00000521437.1
ENST00000520007.1
ENST00000521613.1
caspase recruitment domain family, member 8
chr18_-_10855434 0.03 ENST00000579112.1
piezo-type mechanosensitive ion channel component 2
chr1_+_43613612 0.03 ENST00000335282.4
family with sequence similarity 183, member A
chr5_+_140514782 0.03 ENST00000231134.5
protocadherin beta 5
chr19_-_19626838 0.03 ENST00000360913.3
testis-specific serine kinase 6
chr1_-_154178803 0.03 ENST00000368525.3
chromosome 1 open reading frame 189
chr9_-_133814527 0.03 ENST00000451466.1
fibrinogen C domain containing 1
chr12_-_71148413 0.03 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
protein tyrosine phosphatase, receptor type, R
chr20_-_25320367 0.03 ENST00000450393.1
ENST00000491682.1
abhydrolase domain containing 12
chr18_-_52989217 0.03 ENST00000570287.2
transcription factor 4
chr1_-_143767881 0.03 ENST00000419275.1
peptidylprolyl isomerase A (cyclophilin A)-like 4G
chr4_+_88896819 0.03 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
secreted phosphoprotein 1
chr3_+_187957646 0.03 ENST00000457242.1
LIM domain containing preferred translocation partner in lipoma
chr15_-_85197501 0.03 ENST00000434634.2
WD repeat domain 73
chr20_-_36152914 0.03 ENST00000397131.1
bladder cancer associated protein
chr12_+_57810198 0.03 ENST00000598001.1
HCG1818482; Uncharacterized protein
chr12_+_116985896 0.02 ENST00000547114.1
RP11-809C9.2
chr1_-_230991747 0.02 ENST00000523410.1
chromosome 1 open reading frame 198
chr15_+_75639372 0.02 ENST00000566313.1
ENST00000568059.1
ENST00000568881.1
nei endonuclease VIII-like 1 (E. coli)
chr9_+_131062367 0.02 ENST00000601297.1
CDNA: FLJ21673 fis, clone COL09042; HCG2036511; Uncharacterized protein
chrX_+_36053908 0.02 ENST00000378660.2
calponin homology domain containing 2
chr2_-_40657397 0.02 ENST00000408028.2
ENST00000332839.4
ENST00000406391.2
ENST00000542024.1
ENST00000542756.1
ENST00000405901.3
solute carrier family 8 (sodium/calcium exchanger), member 1
chr2_+_138721850 0.02 ENST00000329366.4
ENST00000280097.3
histamine N-methyltransferase
chr9_+_95736758 0.02 ENST00000337352.6
FYVE, RhoGEF and PH domain containing 3
chr19_+_50016610 0.02 ENST00000596975.1
Fc fragment of IgG, receptor, transporter, alpha
chr2_+_27440229 0.02 ENST00000264705.4
ENST00000403525.1
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chrX_+_65384052 0.02 ENST00000336279.5
ENST00000458621.1
hephaestin
chr21_-_35899113 0.02 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
regulator of calcineurin 1
chr4_+_70861647 0.02 ENST00000246895.4
ENST00000381060.2
statherin
chr6_-_10115007 0.02 ENST00000485268.1
orofacial cleft 1 candidate 1
chr10_+_96698406 0.02 ENST00000260682.6
cytochrome P450, family 2, subfamily C, polypeptide 9
chrX_-_45060135 0.02 ENST00000398000.2
ENST00000377934.4
chromosome X open reading frame 36
chr9_-_133814455 0.02 ENST00000448616.1
fibrinogen C domain containing 1
chr11_-_92930556 0.02 ENST00000529184.1
solute carrier family 36 (proton/amino acid symporter), member 4
chr1_+_46152886 0.02 ENST00000372025.4
transmembrane protein 69
chr1_-_226926864 0.02 ENST00000429204.1
ENST00000366784.1
inositol-trisphosphate 3-kinase B
chr11_-_26744908 0.02 ENST00000533617.1
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr11_+_86748957 0.02 ENST00000526733.1
ENST00000532959.1
transmembrane protein 135
chr7_+_18536090 0.02 ENST00000441986.1
histone deacetylase 9
chr4_-_110723194 0.02 ENST00000394635.3
complement factor I
chr22_-_31324215 0.02 ENST00000429468.1
MORC family CW-type zinc finger 2
chrX_+_73164149 0.02 ENST00000602938.1
ENST00000602294.1
ENST00000602920.1
ENST00000602737.1
ENST00000602772.1
JPX transcript, XIST activator (non-protein coding)
chr10_-_73497581 0.02 ENST00000398786.2
chromosome 10 open reading frame 105
chr9_-_104198042 0.02 ENST00000374855.4
aldolase B, fructose-bisphosphate
chr8_+_21906658 0.02 ENST00000523300.1
dematin actin binding protein
chr1_-_161208013 0.02 ENST00000515452.1
ENST00000367983.4
nuclear receptor subfamily 1, group I, member 3
chr8_-_110660975 0.02 ENST00000528045.1
syntabulin (syntaxin-interacting)
chr19_+_19626531 0.02 ENST00000507754.4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr17_-_73663168 0.02 ENST00000578201.1
ENST00000423245.2
RecQ protein-like 5
chr17_-_29624343 0.02 ENST00000247271.4
oligodendrocyte myelin glycoprotein
chr9_+_130026756 0.02 ENST00000314904.5
ENST00000373387.4
GTPase activating Rap/RanGAP domain-like 3
chr18_+_68002675 0.02 ENST00000584919.1
Uncharacterized protein
chr7_-_78400598 0.02 ENST00000536571.1
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_+_28718921 0.02 ENST00000327757.5
ENST00000422425.2
ENST00000404858.1
phospholipase B1
chr11_-_104972158 0.02 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chrX_+_65384182 0.02 ENST00000441993.2
ENST00000419594.1
hephaestin
chr7_+_129984630 0.02 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
carboxypeptidase A5
chr6_+_53948328 0.02 ENST00000370876.2
muscular LMNA-interacting protein
chr8_+_1993173 0.02 ENST00000523438.1
myomesin 2
chr9_+_105757590 0.02 ENST00000374798.3
ENST00000487798.1
cylicin, basic protein of sperm head cytoskeleton 2
chr16_-_21663950 0.02 ENST00000268389.4
immunoglobulin superfamily, member 6
chr15_+_59910132 0.01 ENST00000559200.1
glucosaminyl (N-acetyl) transferase 3, mucin type
chr8_+_77593448 0.01 ENST00000521891.2
zinc finger homeobox 4
chr1_+_160370344 0.01 ENST00000368061.2
VANGL planar cell polarity protein 2
chr17_+_7211656 0.01 ENST00000416016.2
eukaryotic translation initiation factor 5A
chr17_-_46806540 0.01 ENST00000290295.7
homeobox B13
chr20_+_30697298 0.01 ENST00000398022.2
transmembrane 9 superfamily protein member 4
chr2_+_242913327 0.01 ENST00000426962.1
AC093642.3
chr2_+_161993465 0.01 ENST00000457476.1
TRAF family member-associated NFKB activator
chr12_-_49581152 0.01 ENST00000550811.1
tubulin, alpha 1a
chr2_-_152382500 0.01 ENST00000434685.1
nebulin
chr2_+_220143989 0.01 ENST00000336576.5
DnaJ (Hsp40) homolog, subfamily B, member 2
chr13_-_47471155 0.01 ENST00000543956.1
ENST00000542664.1
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr5_-_139937895 0.01 ENST00000336283.6
steroid receptor RNA activator 1
chr3_-_38992052 0.01 ENST00000302328.3
ENST00000450244.1
ENST00000444237.2
sodium channel, voltage-gated, type XI, alpha subunit
chr6_-_31830655 0.01 ENST00000375631.4
sialidase 1 (lysosomal sialidase)
chr10_+_133747955 0.01 ENST00000455566.1
protein phosphatase 2, regulatory subunit B, delta
chr16_+_71560023 0.01 ENST00000572450.1
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr8_+_1993152 0.01 ENST00000262113.4
myomesin 2
chr9_+_82187487 0.01 ENST00000435650.1
ENST00000414465.1
ENST00000376537.4
ENST00000376534.4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr12_-_71551868 0.01 ENST00000247829.3
tetraspanin 8
chr5_+_140767452 0.01 ENST00000519479.1
protocadherin gamma subfamily B, 4
chr12_-_118628315 0.01 ENST00000540561.1
TAO kinase 3
chr8_-_143859197 0.01 ENST00000395192.2
Ly6/neurotoxin 1
chr8_-_8318847 0.01 ENST00000521218.1
CTA-398F10.2
chr1_+_2985726 0.01 ENST00000511072.1
ENST00000378398.3
ENST00000441472.2
ENST00000442529.2
PR domain containing 16
chr15_+_66797455 0.01 ENST00000446801.2
zwilch kinetochore protein
chr1_-_161207986 0.01 ENST00000506209.1
ENST00000367980.2
nuclear receptor subfamily 1, group I, member 3
chr3_+_89156799 0.01 ENST00000452448.2
ENST00000494014.1
EPH receptor A3
chr7_-_130080977 0.01 ENST00000223208.5
centrosomal protein 41kDa
chr3_+_189507523 0.01 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
tumor protein p63
chrX_+_73164167 0.01 ENST00000414209.1
ENST00000602895.1
ENST00000453317.1
ENST00000602546.1
ENST00000602985.1
ENST00000415215.1
JPX transcript, XIST activator (non-protein coding)
chr12_-_21928515 0.01 ENST00000537950.1
potassium inwardly-rectifying channel, subfamily J, member 8
chr3_-_50375657 0.01 ENST00000395126.3
Ras association (RalGDS/AF-6) domain family member 1
chr4_-_119274121 0.01 ENST00000296498.3
protease, serine, 12 (neurotrypsin, motopsin)
chr17_-_73663245 0.01 ENST00000584999.1
ENST00000317905.5
ENST00000420326.2
ENST00000340830.5
RecQ protein-like 5
chr19_-_19626351 0.01 ENST00000585580.3
testis-specific serine kinase 6
chr1_+_73771844 0.01 ENST00000440762.1
ENST00000444827.1
ENST00000415686.1
ENST00000411903.1
RP4-598G3.1
chr4_-_68829226 0.01 ENST00000396188.2
transmembrane protease, serine 11A
chr4_-_68829144 0.01 ENST00000508048.1
transmembrane protease, serine 11A
chr12_+_25205155 0.01 ENST00000550945.1
lymphoid-restricted membrane protein
chr5_+_140261703 0.01 ENST00000409494.1
ENST00000289272.2
protocadherin alpha 13
chr5_-_88120151 0.01 ENST00000506716.1
myocyte enhancer factor 2C
chr12_-_71551652 0.01 ENST00000546561.1
tetraspanin 8
chr16_-_15180257 0.01 ENST00000540462.1
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr5_-_111312622 0.01 ENST00000395634.3
neuronal regeneration related protein
chr9_+_134065506 0.01 ENST00000483497.2
nucleoporin 214kDa
chr22_-_22292934 0.01 ENST00000538191.1
ENST00000424647.1
ENST00000407142.1
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr15_+_101417919 0.01 ENST00000561338.1
aldehyde dehydrogenase 1 family, member A3
chr9_-_28670283 0.01 ENST00000379992.2
leucine rich repeat and Ig domain containing 2
chr15_+_75639296 0.01 ENST00000564500.1
ENST00000355059.4
ENST00000566752.1
nei endonuclease VIII-like 1 (E. coli)
chr11_+_71900572 0.01 ENST00000312293.4
folate receptor 1 (adult)
chr10_+_24755416 0.01 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
chr5_-_86534822 0.01 ENST00000445770.2
Uncharacterized protein
chr6_+_118869452 0.01 ENST00000357525.5
phospholamban
chr9_-_104145795 0.01 ENST00000259407.2
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr18_-_53069419 0.01 ENST00000570177.2
transcription factor 4
chr4_-_69536346 0.01 ENST00000338206.5
UDP glucuronosyltransferase 2 family, polypeptide B15
chr22_-_23922410 0.01 ENST00000249053.3
immunoglobulin lambda-like polypeptide 1
chr20_+_3767547 0.01 ENST00000344256.6
ENST00000379598.5
cell division cycle 25B
chr6_+_12717892 0.01 ENST00000379350.1
phosphatase and actin regulator 1
chr19_+_29704142 0.01 ENST00000587859.1
ENST00000590607.1
CTB-32O4.2
chr13_-_62001982 0.01 ENST00000409186.1
protocadherin 20
chr5_-_20575959 0.01 ENST00000507958.1
cadherin 18, type 2
chr14_-_81425828 0.01 ENST00000555529.1
ENST00000556042.1
ENST00000556981.1
centrosomal protein 128kDa
chr3_-_178984759 0.01 ENST00000349697.2
ENST00000497599.1
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr3_-_108672742 0.01 ENST00000261047.3
guanylate cyclase activator 1C
chr2_+_31456874 0.01 ENST00000541626.1
EH-domain containing 3
chr10_-_50396407 0.01 ENST00000374153.2
ENST00000374151.3
chromosome 10 open reading frame 128
chr17_-_10452929 0.01 ENST00000532183.2
ENST00000397183.2
ENST00000420805.1
myosin, heavy chain 2, skeletal muscle, adult
chr4_-_71532207 0.01 ENST00000543780.1
ENST00000391614.3
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA10_HOXB9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.1 GO:0035038 female pronucleus assembly(GO:0035038)
0.0 0.1 GO:0042488 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:0002636 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:1990423 RZZ complex(GO:1990423)
0.0 0.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.0 GO:1990032 parallel fiber(GO:1990032)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)