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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for HNF4A
Z-value: 0.82
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Transcription factors associated with HNF4A
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HNF4A | hg19_v2_chr20_+_43029911_43029941 | -0.20 | 7.0e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of HNF4A
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.9 | GO:0097156 | fasciculation of motor neuron axon(GO:0097156) |
| 0.0 | 0.6 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 0.2 | 0.5 | GO:0048203 | vesicle targeting, trans-Golgi to endosome(GO:0048203) |
| 0.2 | 0.5 | GO:0042704 | detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704) |
| 0.0 | 0.5 | GO:0007340 | acrosome reaction(GO:0007340) |
| 0.1 | 0.4 | GO:0015910 | peroxisomal long-chain fatty acid import(GO:0015910) |
| 0.1 | 0.4 | GO:1990569 | UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569) |
| 0.0 | 0.4 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 0.0 | 0.3 | GO:0006438 | valyl-tRNA aminoacylation(GO:0006438) |
| 0.0 | 0.3 | GO:0010960 | magnesium ion homeostasis(GO:0010960) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 0.2 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.0 | 0.2 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.0 | 0.1 | GO:0034669 | integrin alpha4-beta7 complex(GO:0034669) |
| 0.0 | 0.1 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 0.0 | 0.1 | GO:0071006 | U2-type catalytic step 1 spliceosome(GO:0071006) |
| 0.0 | 0.1 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
| 0.0 | 0.0 | GO:0036398 | TCR signalosome(GO:0036398) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.9 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
| 0.1 | 0.6 | GO:0004882 | androgen receptor activity(GO:0004882) |
| 0.1 | 0.5 | GO:0035650 | AP-1 adaptor complex binding(GO:0035650) |
| 0.1 | 0.5 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 0.1 | 0.4 | GO:0005462 | UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462) |
| 0.1 | 0.4 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.0 | 0.3 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
| 0.0 | 0.3 | GO:0004832 | valine-tRNA ligase activity(GO:0004832) |
| 0.0 | 0.3 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.0 | 0.3 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 0.3 | PID CONE PATHWAY | Visual signal transduction: Cones |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.0 | 0.3 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.0 | 0.3 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 0.0 | 0.2 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |