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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HNF1A_HNF1B

Z-value: 0.85

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Transcription factors associated with HNF1A_HNF1B

Gene Symbol Gene ID Gene Info
HNF1A
ENSG00000135100.13 HNF1 homeobox A
HNF1B
ENSG00000108753.8 HNF1 homeobox B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HNF1Bhg19_v2_chr17_-_36105009_361050600.711.1e-01Click!
HNF1Ahg19_v2_chr12_+_121416489_1214165520.572.4e-01Click!

Activity profile of HNF1A_HNF1B motif

Sorted Z-values of HNF1A_HNF1B motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_30899924 0.95 ENST00000359086.3
SFTA2
surfactant associated 2
chr4_-_110723335 0.57 ENST00000394634.2
CFI
complement factor I
chr4_-_110723134 0.51 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr3_-_161089289 0.46 ENST00000497137.1
SPTSSB
serine palmitoyltransferase, small subunit B
chr4_-_110723194 0.46 ENST00000394635.3
CFI
complement factor I
chr4_+_74301880 0.46 ENST00000395792.2
ENST00000226359.2
AFP
alpha-fetoprotein
chr16_-_69385681 0.36 ENST00000288025.3
TMED6
transmembrane emp24 protein transport domain containing 6
chr2_-_47572105 0.35 ENST00000419035.1
ENST00000448713.1
ENST00000450550.1
ENST00000413185.2
AC073283.4
AC073283.4
chr11_-_117170403 0.30 ENST00000504995.1
BACE1
beta-site APP-cleaving enzyme 1
chr2_-_47572207 0.27 ENST00000441997.1
AC073283.4
AC073283.4
chr5_+_176513868 0.25 ENST00000292408.4
FGFR4
fibroblast growth factor receptor 4
chr14_+_39703112 0.24 ENST00000555143.1
ENST00000280082.3
MIA2
melanoma inhibitory activity 2
chr22_-_32767017 0.24 ENST00000400234.1
RFPL3S
RFPL3 antisense
chr5_+_125706998 0.24 ENST00000506445.1
GRAMD3
GRAM domain containing 3
chr10_+_101542462 0.24 ENST00000370449.4
ENST00000370434.1
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr14_-_57960545 0.24 ENST00000526336.1
ENST00000216445.3
C14orf105
chromosome 14 open reading frame 105
chr14_+_65170820 0.23 ENST00000555982.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr4_+_39408470 0.23 ENST00000257408.4
KLB
klotho beta
chr11_-_16419067 0.23 ENST00000533411.1
SOX6
SRY (sex determining region Y)-box 6
chr1_-_204183071 0.23 ENST00000308302.3
GOLT1A
golgi transport 1A
chr14_+_38033252 0.23 ENST00000554829.1
RP11-356O9.1
RP11-356O9.1
chr19_+_49467232 0.22 ENST00000599784.1
ENST00000594305.1
CTD-2639E6.9
CTD-2639E6.9
chr11_-_107729287 0.21 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chr19_+_50016610 0.21 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr20_+_42187682 0.20 ENST00000373092.3
ENST00000373077.1
SGK2
serum/glucocorticoid regulated kinase 2
chr12_+_40787194 0.20 ENST00000425730.2
ENST00000454784.4
MUC19
mucin 19, oligomeric
chr7_-_150020814 0.19 ENST00000477871.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr12_+_25205568 0.19 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr4_-_1166954 0.19 ENST00000514490.1
ENST00000431380.1
ENST00000503765.1
SPON2
spondin 2, extracellular matrix protein
chr16_+_22524379 0.18 ENST00000536620.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr16_+_21244986 0.17 ENST00000311620.5
ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr4_-_987164 0.17 ENST00000398520.2
SLC26A1
solute carrier family 26 (anion exchanger), member 1
chr12_+_25205666 0.17 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr4_+_8201091 0.16 ENST00000382521.3
ENST00000245105.3
ENST00000457650.2
ENST00000539824.1
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr3_-_126327398 0.16 ENST00000383572.2
TXNRD3NB
thioredoxin reductase 3 neighbor
chr20_+_42187608 0.16 ENST00000373100.1
SGK2
serum/glucocorticoid regulated kinase 2
chr6_+_131571535 0.16 ENST00000474850.2
AKAP7
A kinase (PRKA) anchor protein 7
chr1_+_162351503 0.16 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chr12_+_25205628 0.16 ENST00000554942.1
LRMP
lymphoid-restricted membrane protein
chr5_+_176513895 0.15 ENST00000503708.1
ENST00000393648.2
ENST00000514472.1
ENST00000502906.1
ENST00000292410.3
ENST00000510911.1
FGFR4
fibroblast growth factor receptor 4
chr2_+_234601512 0.15 ENST00000305139.6
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr16_+_20775358 0.15 ENST00000440284.2
ACSM3
acyl-CoA synthetase medium-chain family member 3
chr2_+_27719697 0.15 ENST00000264717.2
ENST00000424318.2
GCKR
glucokinase (hexokinase 4) regulator
chr19_+_50016411 0.15 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr11_+_560956 0.14 ENST00000397582.3
ENST00000344375.4
ENST00000397583.3
RASSF7
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr12_+_93096619 0.14 ENST00000397833.3
C12orf74
chromosome 12 open reading frame 74
chr10_+_135340859 0.14 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr1_+_18807424 0.14 ENST00000400664.1
KLHDC7A
kelch domain containing 7A
chr3_-_137834436 0.14 ENST00000327532.2
ENST00000467030.1
DZIP1L
DAZ interacting zinc finger protein 1-like
chr10_+_5135981 0.13 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr7_-_44580861 0.13 ENST00000546276.1
ENST00000289547.4
ENST00000381160.3
ENST00000423141.1
NPC1L1
NPC1-like 1
chr16_+_82068873 0.12 ENST00000566213.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr7_-_150020750 0.12 ENST00000539352.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr12_-_91546926 0.12 ENST00000550758.1
DCN
decorin
chr3_-_169587621 0.11 ENST00000523069.1
ENST00000316428.5
ENST00000264676.5
LRRC31
leucine rich repeat containing 31
chr6_-_154751629 0.11 ENST00000424998.1
CNKSR3
CNKSR family member 3
chr11_-_107729504 0.11 ENST00000265836.7
SLC35F2
solute carrier family 35, member F2
chr2_+_133174147 0.11 ENST00000329321.3
GPR39
G protein-coupled receptor 39
chr16_+_81272287 0.10 ENST00000425577.2
ENST00000564552.1
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr4_-_129207942 0.10 ENST00000503588.1
PGRMC2
progesterone receptor membrane component 2
chr8_-_124749609 0.10 ENST00000262219.6
ENST00000419625.1
ANXA13
annexin A13
chr4_-_69434245 0.10 ENST00000317746.2
UGT2B17
UDP glucuronosyltransferase 2 family, polypeptide B17
chr4_-_129208030 0.10 ENST00000503872.1
PGRMC2
progesterone receptor membrane component 2
chr18_-_2982869 0.10 ENST00000584915.1
LPIN2
lipin 2
chr2_-_74555350 0.09 ENST00000444570.1
SLC4A5
solute carrier family 4 (sodium bicarbonate cotransporter), member 5
chr5_+_140571902 0.09 ENST00000239446.4
PCDHB10
protocadherin beta 10
chr3_-_49466686 0.09 ENST00000273598.3
ENST00000436744.2
NICN1
nicolin 1
chr19_-_43099070 0.09 ENST00000244336.5
CEACAM8
carcinoembryonic antigen-related cell adhesion molecule 8
chr19_+_39138320 0.08 ENST00000424234.2
ENST00000390009.3
ENST00000589528.1
ACTN4
actinin, alpha 4
chr7_+_141695633 0.08 ENST00000549489.2
MGAM
maltase-glucoamylase (alpha-glucosidase)
chr3_-_137893721 0.08 ENST00000505015.2
ENST00000260803.4
DBR1
debranching RNA lariats 1
chr16_-_75284758 0.08 ENST00000561970.1
BCAR1
breast cancer anti-estrogen resistance 1
chr16_+_20775024 0.08 ENST00000289416.5
ACSM3
acyl-CoA synthetase medium-chain family member 3
chr4_-_76944621 0.08 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr13_-_41593425 0.08 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr22_-_22337204 0.08 ENST00000430142.1
ENST00000357179.5
TOP3B
topoisomerase (DNA) III beta
chr14_+_21156915 0.08 ENST00000397990.4
ENST00000555597.1
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr16_+_20911174 0.08 ENST00000568663.1
LYRM1
LYR motif containing 1
chr2_-_228244013 0.08 ENST00000304568.3
TM4SF20
transmembrane 4 L six family member 20
chr6_+_31707725 0.07 ENST00000375755.3
ENST00000375742.3
ENST00000375750.3
ENST00000425703.1
ENST00000534153.4
ENST00000375703.3
ENST00000375740.3
MSH5
mutS homolog 5
chr12_-_8693539 0.07 ENST00000299663.3
CLEC4E
C-type lectin domain family 4, member E
chr22_+_45098067 0.07 ENST00000336985.6
ENST00000403696.1
ENST00000457960.1
ENST00000361473.5
PRR5
PRR5-ARHGAP8
proline rich 5 (renal)
PRR5-ARHGAP8 readthrough
chr17_+_79953310 0.07 ENST00000582355.2
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr8_-_87242589 0.07 ENST00000419776.2
ENST00000297524.3
SLC7A13
solute carrier family 7 (anionic amino acid transporter), member 13
chr4_-_987217 0.07 ENST00000361661.2
ENST00000398516.2
SLC26A1
solute carrier family 26 (anion exchanger), member 1
chr5_+_140772381 0.07 ENST00000398604.2
PCDHGA8
protocadherin gamma subfamily A, 8
chr2_+_28718921 0.07 ENST00000327757.5
ENST00000422425.2
ENST00000404858.1
PLB1
phospholipase B1
chr12_-_15865844 0.07 ENST00000543612.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr17_+_1646130 0.07 ENST00000453066.1
ENST00000324015.3
ENST00000450523.2
ENST00000453723.1
ENST00000382061.4
SERPINF2
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr20_+_62371206 0.07 ENST00000266077.2
SLC2A4RG
SLC2A4 regulator
chr17_+_48823896 0.07 ENST00000511974.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr17_-_36904437 0.06 ENST00000585100.1
ENST00000360797.2
ENST00000578109.1
ENST00000579882.1
PCGF2
polycomb group ring finger 2
chrX_+_120181457 0.06 ENST00000328078.1
GLUD2
glutamate dehydrogenase 2
chr22_-_22337154 0.06 ENST00000413067.2
ENST00000437929.1
ENST00000456075.1
ENST00000434517.1
ENST00000424393.1
ENST00000449704.1
ENST00000437103.1
TOP3B
topoisomerase (DNA) III beta
chr9_-_94712434 0.06 ENST00000375708.3
ROR2
receptor tyrosine kinase-like orphan receptor 2
chr7_+_141695671 0.06 ENST00000497673.1
ENST00000475668.2
MGAM
maltase-glucoamylase (alpha-glucosidase)
chr19_+_29097595 0.06 ENST00000587961.1
AC079466.1
AC079466.1
chr6_-_113953705 0.06 ENST00000452675.1
RP11-367G18.1
RP11-367G18.1
chr11_+_1860200 0.06 ENST00000381911.1
TNNI2
troponin I type 2 (skeletal, fast)
chr11_+_20620946 0.06 ENST00000525748.1
SLC6A5
solute carrier family 6 (neurotransmitter transporter), member 5
chr14_+_62585332 0.06 ENST00000554895.1
LINC00643
long intergenic non-protein coding RNA 643
chr14_+_24590560 0.05 ENST00000558325.1
RP11-468E2.6
RP11-468E2.6
chr5_-_59668541 0.05 ENST00000514552.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr6_+_144665237 0.05 ENST00000421035.2
UTRN
utrophin
chr7_-_104567066 0.05 ENST00000453666.1
RP11-325F22.5
RP11-325F22.5
chr9_+_22646189 0.05 ENST00000436786.1
RP11-399D6.2
RP11-399D6.2
chr3_+_183948161 0.05 ENST00000426955.2
VWA5B2
von Willebrand factor A domain containing 5B2
chr19_+_54466179 0.05 ENST00000270458.2
CACNG8
calcium channel, voltage-dependent, gamma subunit 8
chr5_-_111093167 0.05 ENST00000446294.2
ENST00000419114.2
NREP
neuronal regeneration related protein
chr5_+_67586465 0.05 ENST00000336483.5
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr6_+_144904334 0.05 ENST00000367526.4
UTRN
utrophin
chr3_+_75955817 0.05 ENST00000487694.3
ENST00000602589.1
ROBO2
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr12_+_93096759 0.05 ENST00000544406.2
C12orf74
chromosome 12 open reading frame 74
chr1_+_205197304 0.05 ENST00000358024.3
TMCC2
transmembrane and coiled-coil domain family 2
chr16_-_57832004 0.05 ENST00000562503.1
KIFC3
kinesin family member C3
chr1_+_207262881 0.05 ENST00000451804.2
C4BPB
complement component 4 binding protein, beta
chr17_+_73642486 0.05 ENST00000579469.1
SMIM6
small integral membrane protein 6
chr22_+_32439019 0.04 ENST00000266088.4
SLC5A1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr19_+_39138271 0.04 ENST00000252699.2
ACTN4
actinin, alpha 4
chr19_-_38916839 0.04 ENST00000433821.2
ENST00000426920.2
ENST00000587753.1
ENST00000454404.2
ENST00000293062.9
RASGRP4
RAS guanyl releasing protein 4
chr10_-_38146510 0.04 ENST00000395867.3
ZNF248
zinc finger protein 248
chr10_+_111765562 0.04 ENST00000360162.3
ADD3
adducin 3 (gamma)
chr7_-_143956815 0.04 ENST00000493325.1
OR2A7
olfactory receptor, family 2, subfamily A, member 7
chr13_-_103719196 0.04 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr12_+_60058458 0.04 ENST00000548610.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr6_+_126070726 0.04 ENST00000368364.3
HEY2
hes-related family bHLH transcription factor with YRPW motif 2
chr4_+_108815402 0.04 ENST00000503385.1
SGMS2
sphingomyelin synthase 2
chr1_+_17906970 0.04 ENST00000375415.1
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr9_-_123812542 0.04 ENST00000223642.1
C5
complement component 5
chr17_+_41363854 0.04 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
TMEM106A
transmembrane protein 106A
chr21_-_47575481 0.03 ENST00000291670.5
ENST00000397748.1
ENST00000359679.2
ENST00000355384.2
ENST00000397746.3
ENST00000397743.1
FTCD
formimidoyltransferase cyclodeaminase
chr22_-_30968839 0.03 ENST00000445645.1
ENST00000416358.1
ENST00000423371.1
ENST00000411821.1
ENST00000448604.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr1_+_104293028 0.03 ENST00000370079.3
AMY1C
amylase, alpha 1C (salivary)
chr11_-_117695449 0.03 ENST00000292079.2
FXYD2
FXYD domain containing ion transport regulator 2
chr22_-_38506619 0.03 ENST00000332536.5
ENST00000381669.3
BAIAP2L2
BAI1-associated protein 2-like 2
chr14_-_54425475 0.03 ENST00000559642.1
BMP4
bone morphogenetic protein 4
chr10_-_72648541 0.03 ENST00000299299.3
PCBD1
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
chr12_+_20963632 0.03 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr17_+_68071389 0.03 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr7_+_130126012 0.03 ENST00000341441.5
MEST
mesoderm specific transcript
chr3_+_180319918 0.03 ENST00000296015.4
ENST00000491380.1
ENST00000412756.2
ENST00000382584.4
TTC14
tetratricopeptide repeat domain 14
chrX_+_1710484 0.03 ENST00000313871.3
ENST00000381261.3
AKAP17A
A kinase (PRKA) anchor protein 17A
chr6_-_161085291 0.03 ENST00000316300.5
LPA
lipoprotein, Lp(a)
chr4_-_70518941 0.03 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1
UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr22_+_31003133 0.03 ENST00000405742.3
TCN2
transcobalamin II
chr1_-_110284384 0.03 ENST00000540225.1
GSTM3
glutathione S-transferase mu 3 (brain)
chr4_+_3443614 0.03 ENST00000382774.3
ENST00000511533.1
HGFAC
HGF activator
chr2_+_234526272 0.03 ENST00000373450.4
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr10_-_38146482 0.02 ENST00000374648.3
ZNF248
zinc finger protein 248
chr10_-_52645416 0.02 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
A1CF
APOBEC1 complementation factor
chr6_-_116833500 0.02 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr12_-_91574142 0.02 ENST00000547937.1
DCN
decorin
chr4_-_100212132 0.02 ENST00000209668.2
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chrX_-_124097620 0.02 ENST00000371130.3
ENST00000422452.2
TENM1
teneurin transmembrane protein 1
chr11_-_128894053 0.02 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr17_+_41052808 0.02 ENST00000592383.1
ENST00000253801.2
ENST00000585489.1
G6PC
glucose-6-phosphatase, catalytic subunit
chr6_+_54173227 0.02 ENST00000259782.4
ENST00000370864.3
TINAG
tubulointerstitial nephritis antigen
chr17_+_26800296 0.02 ENST00000444914.3
ENST00000314669.5
SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr22_+_31003190 0.02 ENST00000407817.3
TCN2
transcobalamin II
chr19_+_41305085 0.02 ENST00000303961.4
EGLN2
egl-9 family hypoxia-inducible factor 2
chr1_+_66999799 0.02 ENST00000371035.3
ENST00000371036.3
ENST00000371037.4
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr7_-_47579188 0.02 ENST00000398879.1
ENST00000355730.3
ENST00000442536.2
ENST00000458317.2
TNS3
tensin 3
chr7_+_130126165 0.02 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
MEST
mesoderm specific transcript
chr9_+_140125385 0.02 ENST00000361134.2
SLC34A3
solute carrier family 34 (type II sodium/phosphate contransporter), member 3
chr3_+_107318157 0.02 ENST00000406780.1
BBX
bobby sox homolog (Drosophila)
chr19_-_11639910 0.02 ENST00000588998.1
ENST00000586149.1
ECSIT
ECSIT signalling integrator
chr9_+_82186872 0.02 ENST00000376544.3
ENST00000376520.4
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr1_-_36020531 0.02 ENST00000440579.1
ENST00000494948.1
KIAA0319L
KIAA0319-like
chr7_-_27219632 0.02 ENST00000470747.4
RP1-170O19.20
Uncharacterized protein
chr11_-_83393303 0.02 ENST00000398304.1
ENST00000420775.2
DLG2
discs, large homolog 2 (Drosophila)
chr4_-_22444733 0.02 ENST00000508133.1
GPR125
G protein-coupled receptor 125
chr11_-_26744908 0.02 ENST00000533617.1
SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr22_-_30968813 0.02 ENST00000443111.2
ENST00000443136.1
ENST00000426220.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr5_+_175976324 0.02 ENST00000261944.5
CDHR2
cadherin-related family member 2
chr1_+_84630645 0.02 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr12_-_54653313 0.02 ENST00000550411.1
ENST00000439541.2
CBX5
chromobox homolog 5
chr8_+_20054878 0.02 ENST00000276390.2
ENST00000519667.1
ATP6V1B2
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
chr11_+_2405833 0.02 ENST00000527343.1
ENST00000464784.2
CD81
CD81 molecule
chr2_+_234627424 0.02 ENST00000373409.3
UGT1A4
UDP glucuronosyltransferase 1 family, polypeptide A4
chr4_-_74486217 0.02 ENST00000335049.5
ENST00000307439.5
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr4_-_166034029 0.01 ENST00000306480.6
TMEM192
transmembrane protein 192
chr8_-_17752996 0.01 ENST00000381841.2
ENST00000427924.1
FGL1
fibrinogen-like 1
chr16_-_15474904 0.01 ENST00000534094.1
NPIPA5
nuclear pore complex interacting protein family, member A5
chr6_-_127840336 0.01 ENST00000525778.1
SOGA3
SOGA family member 3
chr11_+_46740730 0.01 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
F2
coagulation factor II (thrombin)
chr2_-_169104651 0.01 ENST00000355999.4
STK39
serine threonine kinase 39
chr19_+_6464243 0.01 ENST00000600229.1
ENST00000356762.3
CRB3
crumbs homolog 3 (Drosophila)
chr8_+_104892639 0.01 ENST00000436393.2
RIMS2
regulating synaptic membrane exocytosis 2
chr14_-_94759361 0.01 ENST00000393096.1
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr7_-_150020578 0.01 ENST00000478393.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr3_-_157221128 0.01 ENST00000392833.2
ENST00000362010.2
VEPH1
ventricular zone expressed PH domain-containing 1
chrX_+_48660107 0.01 ENST00000376643.2
HDAC6
histone deacetylase 6
chr1_+_36789335 0.01 ENST00000373137.2
RP11-268J15.5
RP11-268J15.5
chr14_-_65409438 0.01 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr3_-_157221380 0.01 ENST00000468233.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr5_+_40841276 0.01 ENST00000254691.5
CARD6
caspase recruitment domain family, member 6
chr15_+_58430567 0.01 ENST00000536493.1
AQP9
aquaporin 9
chr1_-_207206092 0.01 ENST00000359470.5
ENST00000461135.2
C1orf116
chromosome 1 open reading frame 116
chr16_-_57831676 0.01 ENST00000465878.2
ENST00000539578.1
ENST00000561524.1
KIFC3
kinesin family member C3
chr2_+_234621551 0.01 ENST00000608381.1
ENST00000373414.3
UGT1A1
UGT1A5
UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5

Network of associatons between targets according to the STRING database.

First level regulatory network of HNF1A_HNF1B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 0.2 GO:0050787 detoxification of mercury ion(GO:0050787)
0.1 0.5 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.1 0.2 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.3 GO:1903412 response to bile acid(GO:1903412)
0.0 0.1 GO:2000224 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.1 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.0 0.2 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.2 GO:1904970 brush border assembly(GO:1904970)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.5 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 1.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.2 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0 0.1 GO:0002034 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.0 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.0 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.0 0.2 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.5 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.5 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0047017 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0016160 amylase activity(GO:0016160)
0.0 1.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.0 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505) 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.0 0.0 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.2 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation