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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HMX3

Z-value: 0.73

Motif logo

Transcription factors associated with HMX3

Gene Symbol Gene ID Gene Info
ENSG00000188620.9 H6 family homeobox 3

Activity profile of HMX3 motif

Sorted Z-values of HMX3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_86861660 0.79 ENST00000486215.1
outer dense fiber of sperm tails 2-like
chr9_-_95055923 0.69 ENST00000430417.1
isoleucyl-tRNA synthetase
chr12_+_51318513 0.50 ENST00000332160.4
methyltransferase like 7A
chr4_+_75174180 0.49 ENST00000413830.1
epithelial mitogen
chr3_+_38537960 0.45 ENST00000453767.1
endo/exonuclease (5'-3'), endonuclease G-like
chr3_-_195076933 0.39 ENST00000423531.1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr5_+_146614579 0.36 ENST00000541094.1
ENST00000398521.3
serine/threonine kinase 32A
chr11_+_63304273 0.36 ENST00000439013.2
ENST00000255688.3
retinoic acid receptor responder (tazarotene induced) 3
chr19_+_9361606 0.35 ENST00000456448.1
olfactory receptor, family 7, subfamily E, member 24
chr7_-_35013217 0.34 ENST00000446375.1
dpy-19-like 1 (C. elegans)
chr5_-_142077569 0.33 ENST00000407758.1
ENST00000441680.2
ENST00000419524.2
fibroblast growth factor 1 (acidic)
chr7_-_77325545 0.32 ENST00000447009.1
ENST00000416650.1
ENST00000440088.1
ENST00000430801.1
ENST00000398043.2
RSBN1L antisense RNA 1
chrX_-_43741594 0.30 ENST00000536181.1
ENST00000378069.4
monoamine oxidase B
chr12_-_10601963 0.30 ENST00000543893.1
killer cell lectin-like receptor subfamily C, member 1
chr8_-_95487272 0.30 ENST00000297592.5
RAD54 homolog B (S. cerevisiae)
chr2_-_55237484 0.30 ENST00000394609.2
reticulon 4
chr9_+_109685630 0.29 ENST00000451160.2
Uncharacterized protein
chr5_+_42756903 0.29 ENST00000361970.5
ENST00000388827.4
coiled-coil domain containing 152
chr12_-_10022735 0.29 ENST00000228438.2
C-type lectin domain family 2, member B
chrX_-_55208866 0.28 ENST00000545075.1
MT-RNR2-like 10
chr8_-_95487331 0.28 ENST00000336148.5
RAD54 homolog B (S. cerevisiae)
chr9_+_123884038 0.28 ENST00000373847.1
centriolin
chr4_+_83956312 0.28 ENST00000509317.1
ENST00000503682.1
ENST00000511653.1
COP9 signalosome subunit 4
chr16_-_56701933 0.28 ENST00000568675.1
ENST00000569500.1
ENST00000444837.2
ENST00000379811.3
metallothionein 1G
chr16_-_70239683 0.28 ENST00000601706.1
Uncharacterized protein
chr15_+_42697065 0.27 ENST00000565559.1
calpain 3, (p94)
chr5_-_42812143 0.27 ENST00000514985.1
selenoprotein P, plasma, 1
chr19_+_58193388 0.27 ENST00000596085.1
ENST00000594684.1
zinc finger protein 551
Uncharacterized protein
chr18_+_76829441 0.27 ENST00000458297.2
ATPase, class II, type 9B
chr1_+_87012922 0.27 ENST00000263723.5
chloride channel accessory 4
chr18_+_61254534 0.26 ENST00000269489.5
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr1_+_160709055 0.26 ENST00000368043.3
ENST00000368042.3
ENST00000458602.2
ENST00000458104.2
SLAM family member 7
chr16_+_57139933 0.26 ENST00000566259.1
copine II
chr2_-_68290106 0.26 ENST00000407324.1
ENST00000355848.3
ENST00000409302.1
ENST00000410067.3
C1D nuclear receptor corepressor
chr20_+_5986727 0.25 ENST00000378863.4
cardiolipin synthase 1
chr6_-_135271219 0.25 ENST00000367847.2
ENST00000367845.2
aldehyde dehydrogenase 8 family, member A1
chr6_-_26199471 0.24 ENST00000341023.1
histone cluster 1, H2ad
chr5_-_102898465 0.24 ENST00000507423.1
ENST00000230792.2
nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr4_-_112993808 0.23 ENST00000511219.1
RP11-269F21.3
chr8_-_71157595 0.23 ENST00000519724.1
nuclear receptor coactivator 2
chr1_-_108231101 0.23 ENST00000544443.1
ENST00000415432.2
vav 3 guanine nucleotide exchange factor
chr18_+_76829385 0.23 ENST00000426216.2
ENST00000307671.7
ENST00000586672.1
ENST00000586722.1
ATPase, class II, type 9B
chr21_+_17791648 0.23 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
long intergenic non-protein coding RNA 478
chr9_+_130159433 0.23 ENST00000451404.1
solute carrier family 2 (facilitated glucose transporter), member 8
chr18_+_61254570 0.23 ENST00000344731.5
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr20_+_19738300 0.22 ENST00000432334.1
RP1-122P22.2
chr7_+_39605966 0.22 ENST00000223273.2
ENST00000448268.1
ENST00000432096.2
Yae1 domain containing 1
chr12_+_25205568 0.22 ENST00000548766.1
ENST00000556887.1
lymphoid-restricted membrane protein
chr2_+_242312264 0.22 ENST00000445489.1
FERM, RhoGEF and pleckstrin domain protein 2
chr12_+_57810198 0.22 ENST00000598001.1
HCG1818482; Uncharacterized protein
chr14_+_96000930 0.22 ENST00000331334.4
glutaredoxin 5
chr7_+_29603394 0.22 ENST00000319694.2
proline rich 15
chrX_+_13671225 0.22 ENST00000545566.1
ENST00000544987.1
ENST00000314720.4
transcription elongation factor A (SII) N-terminal and central domain containing
chr19_+_10222189 0.22 ENST00000321826.4
purinergic receptor P2Y, G-protein coupled, 11
chrX_-_1331527 0.21 ENST00000381567.3
ENST00000381566.1
ENST00000400841.2
cytokine receptor-like factor 2
chr2_+_97454321 0.21 ENST00000540067.1
cyclin M4
chr4_-_39034542 0.21 ENST00000344606.6
transmembrane protein 156
chr5_+_147691979 0.21 ENST00000274565.4
serine peptidase inhibitor, Kazal type 7 (putative)
chr16_+_70258261 0.21 ENST00000594734.1
FKSG63
chr9_-_21482312 0.21 ENST00000448696.3
interferon, epsilon
chr1_-_244006528 0.21 ENST00000336199.5
ENST00000263826.5
v-akt murine thymoma viral oncogene homolog 3
chr3_+_111697843 0.21 ENST00000534857.1
ENST00000273359.3
ENST00000494817.1
abhydrolase domain containing 10
chr14_+_50291993 0.20 ENST00000595378.1
HCG1786899; PRO2610; Uncharacterized protein
chr5_+_95066823 0.20 ENST00000506817.1
ENST00000379982.3
Rho-related BTB domain containing 3
chr5_+_112849373 0.20 ENST00000161863.4
ENST00000515883.1
YTH domain containing 2
chr22_-_29107919 0.19 ENST00000434810.1
ENST00000456369.1
checkpoint kinase 2
chr14_+_23025534 0.19 ENST00000557595.1
Uncharacterized protein
chr2_+_90458201 0.19 ENST00000603238.1
Uncharacterized protein
chr16_+_53412368 0.19 ENST00000565189.1
RP11-44F14.2
chr9_+_71986182 0.19 ENST00000303068.7
family with sequence similarity 189, member A2
chr15_-_60771128 0.19 ENST00000558512.1
ENST00000561114.1
NMDA receptor regulated 2
chr1_+_87012753 0.19 ENST00000370563.3
chloride channel accessory 4
chr19_+_507299 0.19 ENST00000359315.5
tubulin polyglutamylase complex subunit 1
chrX_+_119737806 0.19 ENST00000371317.5
malignant T cell amplified sequence 1
chr21_+_25801041 0.19 ENST00000453784.2
ENST00000423581.1
AP000476.1
chr11_+_65266507 0.19 ENST00000544868.1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr19_+_42212526 0.18 ENST00000598976.1
ENST00000435837.2
ENST00000221992.6
ENST00000405816.1
Uncharacterized protein
carcinoembryonic antigen-related cell adhesion molecule 5
chr19_+_40195101 0.18 ENST00000360675.3
ENST00000601802.1
lectin, galactoside-binding, soluble, 14
chr6_-_35656685 0.18 ENST00000539068.1
ENST00000540787.1
FK506 binding protein 5
chr4_+_83956237 0.18 ENST00000264389.2
COP9 signalosome subunit 4
chr1_+_53480598 0.18 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
sterol carrier protein 2
chr14_+_32798547 0.18 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
A kinase (PRKA) anchor protein 6
chr1_-_152061537 0.18 ENST00000368806.1
trichohyalin-like 1
chr3_-_11685345 0.18 ENST00000430365.2
vestigial like 4 (Drosophila)
chr5_+_169011033 0.18 ENST00000513795.1
spindle apparatus coiled-coil protein 1
chr13_+_108921977 0.18 ENST00000430559.1
ENST00000375887.4
tumor necrosis factor (ligand) superfamily, member 13b
chr4_-_14889791 0.18 ENST00000509654.1
ENST00000515031.1
ENST00000505089.2
long intergenic non-protein coding RNA 504
chr8_+_42396274 0.18 ENST00000438528.3
small integral membrane protein 19
chr7_-_92146729 0.18 ENST00000541751.1
peroxisomal biogenesis factor 1
chr6_-_46138676 0.18 ENST00000371383.2
ENST00000230565.3
ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
chr19_+_52772821 0.18 ENST00000439461.1
zinc finger protein 766
chr4_-_104020968 0.18 ENST00000504285.1
3-hydroxybutyrate dehydrogenase, type 2
chr8_-_27695552 0.17 ENST00000522944.1
ENST00000301905.4
PDZ binding kinase
chr1_-_152779104 0.17 ENST00000606576.1
ENST00000368768.1
late cornified envelope 1C
chr1_+_160709029 0.17 ENST00000444090.2
ENST00000441662.2
SLAM family member 7
chr8_-_6115044 0.17 ENST00000519555.1
RP11-124B13.1
chr2_+_103089756 0.17 ENST00000295269.4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chr14_+_102196739 0.17 ENST00000556973.1
Uncharacterized protein
chr19_+_41281416 0.17 ENST00000597140.1
melanoma inhibitory activity
chr6_+_26124373 0.17 ENST00000377791.2
ENST00000602637.1
histone cluster 1, H2ac
chr4_+_25915896 0.17 ENST00000514384.1
small integral membrane protein 20
chr1_-_110933611 0.17 ENST00000472422.2
ENST00000437429.2
solute carrier family 16, member 4
chr1_+_160709076 0.17 ENST00000359331.4
ENST00000495334.1
SLAM family member 7
chr1_+_171060018 0.17 ENST00000367755.4
ENST00000392085.2
ENST00000542847.1
ENST00000538429.1
ENST00000479749.1
flavin containing monooxygenase 3
chr10_-_61900762 0.17 ENST00000355288.2
ankyrin 3, node of Ranvier (ankyrin G)
chr6_+_134274354 0.17 ENST00000367869.1
TBP-like 1
chr11_-_62323702 0.17 ENST00000530285.1
AHNAK nucleoprotein
chr19_+_45844032 0.17 ENST00000589837.1
kinesin light chain 3
chr12_+_28299014 0.17 ENST00000538586.1
ENST00000536154.1
coiled-coil domain containing 91
chr8_-_121457332 0.16 ENST00000518918.1
mitochondrial ribosomal protein L13
chr12_+_12202785 0.16 ENST00000586576.1
ENST00000464885.2
BCL2-like 14 (apoptosis facilitator)
chr3_+_149535022 0.16 ENST00000466795.1
ring finger protein 13
chr11_-_104893863 0.16 ENST00000260315.3
ENST00000526056.1
ENST00000531367.1
ENST00000456094.1
ENST00000444749.2
ENST00000393141.2
ENST00000418434.1
ENST00000393139.2
caspase 5, apoptosis-related cysteine peptidase
chr1_-_149459549 0.16 ENST00000369175.3
family with sequence similarity 72, member C
chr1_-_160549235 0.16 ENST00000368054.3
ENST00000368048.3
ENST00000311224.4
ENST00000368051.3
ENST00000534968.1
CD84 molecule
chr12_+_128399965 0.16 ENST00000540882.1
ENST00000542089.1
long intergenic non-protein coding RNA 507
chrX_+_105937068 0.16 ENST00000324342.3
ring finger protein 128, E3 ubiquitin protein ligase
chr2_-_111334678 0.16 ENST00000329516.3
ENST00000330331.5
ENST00000446930.1
RANBP2-like and GRIP domain containing 6
chr7_+_39773160 0.16 ENST00000340510.4
long intergenic non-protein coding RNA 265
chr18_-_74839891 0.16 ENST00000581878.1
myelin basic protein
chr20_-_271304 0.15 ENST00000400269.3
ENST00000360321.2
chromosome 20 open reading frame 96
chr17_-_40828969 0.15 ENST00000591022.1
ENST00000587627.1
ENST00000293349.6
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr7_+_33168856 0.15 ENST00000432983.1
Bardet-Biedl syndrome 9
chr9_-_27005686 0.15 ENST00000380055.5
leucine rich repeat containing 19
chr5_+_150404904 0.15 ENST00000521632.1
glutathione peroxidase 3 (plasma)
chrX_+_38420623 0.15 ENST00000378482.2
tetraspanin 7
chr13_-_79233314 0.15 ENST00000282003.6
ring finger protein 219
chr15_-_56757329 0.15 ENST00000260453.3
meiosis-specific nuclear structural 1
chr18_+_2571510 0.15 ENST00000261597.4
ENST00000575515.1
NDC80 kinetochore complex component
chr4_+_159131596 0.15 ENST00000512481.1
transmembrane protein 144
chr5_-_74162605 0.15 ENST00000389156.4
ENST00000510496.1
ENST00000380515.3
family with sequence similarity 169, member A
chrX_+_2670153 0.15 ENST00000509484.2
Xg blood group
chr14_+_89290965 0.15 ENST00000345383.5
ENST00000536576.1
ENST00000346301.4
ENST00000338104.6
ENST00000354441.6
ENST00000380656.2
ENST00000556651.1
ENST00000554686.1
tetratricopeptide repeat domain 8
chr7_-_64023441 0.15 ENST00000309683.6
zinc finger protein 680
chr4_+_83821835 0.15 ENST00000302236.5
THAP domain containing 9
chr10_+_5238793 0.14 ENST00000263126.1
aldo-keto reductase family 1, member C4
chr6_-_35656712 0.14 ENST00000357266.4
ENST00000542713.1
FK506 binding protein 5
chr1_+_62439037 0.14 ENST00000545929.1
InaD-like (Drosophila)
chr3_+_88198838 0.14 ENST00000318887.3
chromosome 3 open reading frame 38
chr20_+_52824367 0.14 ENST00000371419.2
prefoldin subunit 4
chr19_-_44384291 0.14 ENST00000324394.6
zinc finger protein 404
chr4_+_109571740 0.14 ENST00000361564.4
oligosaccharyltransferase complex subunit (non-catalytic)
chr10_-_99030395 0.14 ENST00000355366.5
ENST00000371027.1
Rho GTPase activating protein 19
chr14_-_74025625 0.14 ENST00000553558.1
ENST00000563329.1
ENST00000334988.2
ENST00000560393.1
HEAT repeat containing 4
chr3_-_170588163 0.14 ENST00000295830.8
ribosomal protein L22-like 1
chrX_+_12809463 0.14 ENST00000380663.3
ENST00000380668.5
ENST00000398491.2
ENST00000489404.1
phosphoribosyl pyrophosphate synthetase 2
chr14_+_57857262 0.13 ENST00000555166.1
ENST00000556492.1
ENST00000554703.1
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr1_+_99127225 0.13 ENST00000370189.5
ENST00000529992.1
sorting nexin 7
chr11_-_14521349 0.13 ENST00000534234.1
coatomer protein complex, subunit beta 1
chr8_+_1993173 0.13 ENST00000523438.1
myomesin 2
chr12_+_32115400 0.13 ENST00000381054.3
KIAA1551
chr12_+_7052974 0.13 ENST00000544681.1
ENST00000537087.1
chromosome 12 open reading frame 57
chr4_+_56815102 0.13 ENST00000257287.4
centrosomal protein 135kDa
chr20_-_45530365 0.13 ENST00000414085.1
RP11-323C15.2
chr12_+_128399917 0.13 ENST00000544645.1
long intergenic non-protein coding RNA 507
chr17_-_40829026 0.13 ENST00000412503.1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr6_-_26199499 0.13 ENST00000377831.5
histone cluster 1, H3d
chr3_+_121613265 0.12 ENST00000295605.2
solute carrier family 15 (oligopeptide transporter), member 2
chrX_+_38420783 0.12 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
tetraspanin 7
chr13_-_47471155 0.12 ENST00000543956.1
ENST00000542664.1
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr4_-_120243545 0.12 ENST00000274024.3
fatty acid binding protein 2, intestinal
chr2_+_211342400 0.12 ENST00000417946.1
ENST00000518043.1
ENST00000523702.1
carbamoyl-phosphate synthase 1, mitochondrial
chr7_-_130066571 0.12 ENST00000492389.1
centrosomal protein 41kDa
chr10_-_46089939 0.12 ENST00000453980.3
membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
chr6_-_135271260 0.12 ENST00000265605.2
aldehyde dehydrogenase 8 family, member A1
chr12_+_107712173 0.12 ENST00000280758.5
ENST00000420571.2
BTB (POZ) domain containing 11
chr1_+_117963209 0.12 ENST00000449370.2
mannosidase, alpha, class 1A, member 2
chr1_-_53387352 0.12 ENST00000541281.1
enoyl CoA hydratase domain containing 2
chr12_+_29302119 0.12 ENST00000536681.3
fatty acyl CoA reductase 2
chr5_+_68665608 0.12 ENST00000509734.1
ENST00000354868.5
ENST00000521422.1
ENST00000354312.3
ENST00000345306.6
RAD17 homolog (S. pombe)
chr2_-_134326009 0.12 ENST00000409261.1
ENST00000409213.1
NCK-associated protein 5
chr2_-_211342292 0.12 ENST00000448951.1
LanC lantibiotic synthetase component C-like 1 (bacterial)
chr1_+_186798073 0.12 ENST00000367466.3
ENST00000442353.2
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr19_-_22034809 0.12 ENST00000594012.1
ENST00000595461.1
ENST00000596899.1
zinc finger protein 43
chr5_+_61601965 0.12 ENST00000401507.3
kinesin heavy chain member 2A
chr4_-_47465666 0.12 ENST00000381571.4
COMM domain containing 8
chr1_-_110933663 0.12 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
solute carrier family 16, member 4
chr5_+_61602055 0.12 ENST00000381103.2
kinesin heavy chain member 2A
chr17_-_29641104 0.12 ENST00000577894.1
ENST00000330927.4
ecotropic viral integration site 2B
chr10_-_18948156 0.12 ENST00000414939.1
ENST00000449529.1
ENST00000456217.1
ENST00000444660.1
ARL5B antisense RNA 1
chr6_+_148663729 0.12 ENST00000367467.3
SAM and SH3 domain containing 1
chr15_-_47426320 0.11 ENST00000557832.1
FKSG62
chr5_+_146614679 0.11 ENST00000398523.3
serine/threonine kinase 32A
chr18_-_66382289 0.11 ENST00000443099.2
ENST00000562706.1
ENST00000544714.2
thioredoxin-related transmembrane protein 3
chr12_+_122688090 0.11 ENST00000324189.4
ENST00000546192.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr8_+_134125727 0.11 ENST00000521107.1
thyroglobulin
chr7_-_112430647 0.11 ENST00000312814.6
transmembrane protein 168
chr1_+_170501270 0.11 ENST00000367763.3
ENST00000367762.1
golgin, RAB6-interacting
chr15_+_65843130 0.11 ENST00000569894.1
protein tyrosine phosphatase-like A domain containing 1
chr6_-_26124138 0.11 ENST00000314332.5
ENST00000396984.1
histone cluster 1, H2bc
chr13_-_49987885 0.11 ENST00000409082.1
calcium binding protein 39-like
chr6_+_26217159 0.11 ENST00000303910.2
histone cluster 1, H2ae
chr8_-_17555164 0.11 ENST00000297488.6
microtubule associated tumor suppressor 1
chr19_-_52255107 0.11 ENST00000595042.1
ENST00000304748.4
formyl peptide receptor 1
chr9_-_5833027 0.11 ENST00000339450.5
endoplasmic reticulum metallopeptidase 1
chr1_-_54411255 0.11 ENST00000371377.3
heat shock protein family B (small), member 11
chr14_+_65381079 0.11 ENST00000549115.1
ENST00000607599.1
ENST00000548752.2
ENST00000359118.2
ENST00000552002.2
ENST00000551947.1
ENST00000551093.1
ENST00000542227.1
ENST00000447296.2
ENST00000549987.1
churchill domain containing 1
farnesyltransferase, CAAX box, beta
CHURC1-FNTB readthrough
chr11_-_64684672 0.11 ENST00000377264.3
ENST00000421419.2
autophagy related 2A
chr7_+_91570165 0.11 ENST00000356239.3
ENST00000359028.2
ENST00000358100.2
A kinase (PRKA) anchor protein 9
chr19_+_58193337 0.11 ENST00000601064.1
ENST00000282296.5
ENST00000356715.4
zinc finger protein 551

Network of associatons between targets according to the STRING database.

First level regulatory network of HMX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.2 0.5 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.1 0.2 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 0.2 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.2 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.3 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.1 0.3 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.2 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.0 0.2 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.3 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.0 GO:0042148 strand invasion(GO:0042148)
0.0 0.1 GO:0070409 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.3 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.2 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.4 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.3 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.1 GO:0034059 response to anoxia(GO:0034059)
0.0 0.3 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:0007210 serotonin receptor signaling pathway(GO:0007210) positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.4 GO:1904847 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.2 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.1 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.2 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.2 GO:0035633 maintenance of blood-brain barrier(GO:0035633) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.2 GO:0009820 alkaloid metabolic process(GO:0009820)
0.0 0.2 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.1 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.2 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.2 GO:1900003 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.2 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.0 0.4 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0045354 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.1 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.2 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.2 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.1 GO:0050893 sensory processing(GO:0050893)
0.0 0.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.1 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.3 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.2 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.2 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.2 GO:0070269 ectopic germ cell programmed cell death(GO:0035234) pyroptosis(GO:0070269)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.2 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.3 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.7 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.1 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.6 GO:0006312 mitotic recombination(GO:0006312)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.3 GO:0042117 monocyte activation(GO:0042117)
0.0 0.0 GO:0003095 pressure natriuresis(GO:0003095)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.4 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.0 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.2 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.0 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.1 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.2 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.1 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.0 GO:0010710 regulation of collagen catabolic process(GO:0010710)
0.0 0.0 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.0 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.1 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.0 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.0 0.1 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0098552 side of membrane(GO:0098552)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.7 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 0.6 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.2 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.1 0.2 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.3 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.3 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.1 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.0 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.2 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.2 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.3 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.1 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.2 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.0 0.3 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.1 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0047661 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.1 GO:0047756 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.1 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.5 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.0 GO:0018685 alkane 1-monooxygenase activity(GO:0018685) tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.0 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.0 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins