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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for HMBOX1
Z-value: 0.69
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Transcription factors associated with HMBOX1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HMBOX1 | hg19_v2_chr8_+_28747884_28747938 | 0.50 | 3.2e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of HMBOX1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:1902570 | protein localization to nucleolus(GO:1902570) |
| 0.1 | 0.3 | GO:0002528 | regulation of vascular permeability involved in acute inflammatory response(GO:0002528) |
| 0.0 | 0.2 | GO:0036369 | transcription factor catabolic process(GO:0036369) |
| 0.0 | 0.2 | GO:0031666 | positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666) |
| 0.0 | 0.2 | GO:0089700 | protein kinase D signaling(GO:0089700) |
| 0.0 | 0.2 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
| 0.0 | 0.2 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 0.0 | 0.2 | GO:0032074 | negative regulation of nuclease activity(GO:0032074) |
| 0.0 | 0.2 | GO:0052695 | cellular glucuronidation(GO:0052695) |
| 0.0 | 0.1 | GO:1901873 | regulation of post-translational protein modification(GO:1901873) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.0 | 0.2 | GO:0005927 | muscle tendon junction(GO:0005927) |
| 0.0 | 0.2 | GO:0002177 | manchette(GO:0002177) |
| 0.0 | 0.2 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 0.1 | GO:0031251 | PAN complex(GO:0031251) |
| 0.0 | 0.1 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
| 0.0 | 0.1 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
| 0.0 | 0.1 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.0 | 0.1 | GO:0005715 | late recombination nodule(GO:0005715) |
| 0.0 | 0.1 | GO:0036128 | CatSper complex(GO:0036128) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.0 | 0.3 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.1 | 0.2 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
| 0.0 | 0.2 | GO:0052740 | 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740) |
| 0.0 | 0.2 | GO:0019534 | toxin transporter activity(GO:0019534) |
| 0.0 | 0.2 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.0 | 0.2 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 0.1 | GO:0070546 | L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130) |
| 0.0 | 0.1 | GO:0004513 | neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291) |
| 0.0 | 0.1 | GO:0097363 | protein O-GlcNAc transferase activity(GO:0097363) |